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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF773-SNRPD2 (FusionGDB2 ID:102901)

Fusion Gene Summary for ZNF773-SNRPD2

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF773-SNRPD2
Fusion gene ID: 102901
HgeneTgene
Gene symbol

ZNF773

SNRPD2

Gene ID

374928

6633

Gene namezinc finger protein 773small nuclear ribonucleoprotein D2 polypeptide
SynonymsZNF419BSMD2|SNRPD1|Sm-D2
Cytomap

19q13.43

19q13.32

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 773zinc finger protein 419Bsmall nuclear ribonucleoprotein Sm D2small nuclear ribonucleoprotein D2 polypeptide 16.5kDasnRNP core protein D2
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000282292, ENST00000593916, 
ENST00000598770, ENST00000599847, 
ENST00000391932, ENST00000585392, 
ENST00000587367, ENST00000588301, 
ENST00000588599, ENST00000590212, 
ENST00000587579, ENST00000342669, 
Fusion gene scores* DoF score2 X 3 X 2=1211 X 10 X 4=440
# samples 212
** MAII scorelog2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(12/440*10)=-1.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF773 [Title/Abstract] AND SNRPD2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF773(58016154)-SNRPD2(46190985), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSNRPD2

GO:0000387

spliceosomal snRNP assembly

18984161

TgeneSNRPD2

GO:0000398

mRNA splicing, via spliceosome

28076346


check buttonFusion gene breakpoints across ZNF773 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SNRPD2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-32-1970-01AZNF773chr19

58016154

+SNRPD2chr19

46190985

-
ChimerDB4GBMTCGA-32-1970-01AZNF773chr19

58016768

+SNRPD2chr19

46190985

-


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Fusion Gene ORF analysis for ZNF773-SNRPD2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000282292ENST00000391932ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000391932ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000585392ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000585392ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000587367ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000587367ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000588301ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000588301ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000588599ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000588599ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000590212ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000282292ENST00000590212ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000391932ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000391932ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000585392ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000585392ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000587367ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000587367ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000588301ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000588301ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000588599ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000588599ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000590212ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000593916ENST00000590212ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000391932ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000391932ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000585392ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000585392ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000587367ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000587367ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000588301ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000588301ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000588599ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000588599ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000590212ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000598770ENST00000590212ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000391932ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000391932ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000585392ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000585392ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000587367ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000587367ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000588301ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000588301ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000588599ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000588599ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000590212ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-5UTRENST00000599847ENST00000590212ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-intronENST00000282292ENST00000587579ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-intronENST00000282292ENST00000587579ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-intronENST00000593916ENST00000587579ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-intronENST00000593916ENST00000587579ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-intronENST00000598770ENST00000587579ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-intronENST00000598770ENST00000587579ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
5CDS-intronENST00000599847ENST00000587579ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
5CDS-intronENST00000599847ENST00000587579ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
In-frameENST00000282292ENST00000342669ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
In-frameENST00000282292ENST00000342669ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
In-frameENST00000593916ENST00000342669ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
In-frameENST00000593916ENST00000342669ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
In-frameENST00000598770ENST00000342669ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
In-frameENST00000598770ENST00000342669ZNF773chr19

58016768

+SNRPD2chr19

46190985

-
In-frameENST00000599847ENST00000342669ZNF773chr19

58016154

+SNRPD2chr19

46190985

-
In-frameENST00000599847ENST00000342669ZNF773chr19

58016768

+SNRPD2chr19

46190985

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000593916ZNF773chr1958016154+ENST00000342669SNRPD2chr1946190985-60032641114887
ENST00000598770ZNF773chr1958016154+ENST00000342669SNRPD2chr1946190985-580306119564
ENST00000599847ZNF773chr1958016154+ENST00000342669SNRPD2chr1946190985-57930514233363
ENST00000282292ZNF773chr1958016154+ENST00000342669SNRPD2chr1946190985-57730314033163
ENST00000593916ZNF773chr1958016768+ENST00000342669SNRPD2chr1946190985-69942516645395
ENST00000598770ZNF773chr1958016768+ENST00000342669SNRPD2chr1946190985-67940514643395
ENST00000599847ZNF773chr1958016768+ENST00000342669SNRPD2chr1946190985-67840414243296
ENST00000282292ZNF773chr1958016768+ENST00000342669SNRPD2chr1946190985-67640214043096

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000593916ENST00000342669ZNF773chr1958016154+SNRPD2chr1946190985-0.129781990.87021804
ENST00000598770ENST00000342669ZNF773chr1958016154+SNRPD2chr1946190985-0.176545750.8234543
ENST00000599847ENST00000342669ZNF773chr1958016154+SNRPD2chr1946190985-0.095617060.9043829
ENST00000282292ENST00000342669ZNF773chr1958016154+SNRPD2chr1946190985-0.077769230.9222307
ENST00000593916ENST00000342669ZNF773chr1958016768+SNRPD2chr1946190985-0.1219995840.8780004
ENST00000598770ENST00000342669ZNF773chr1958016768+SNRPD2chr1946190985-0.150963020.84903693
ENST00000599847ENST00000342669ZNF773chr1958016768+SNRPD2chr1946190985-0.0977690150.902231
ENST00000282292ENST00000342669ZNF773chr1958016768+SNRPD2chr1946190985-0.085514090.91448593

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Fusion Genomic Features for ZNF773-SNRPD2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNF773-SNRPD2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:58016154/chr19:46190985)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+3415_8687443.0DomainKRAB
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+3415_8686442.0DomainKRAB

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+2415_8654443.0DomainKRAB
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+2415_8653442.0DomainKRAB
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24191_21354443.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24219_24154443.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24247_26954443.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24275_29754443.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24303_32554443.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24331_35354443.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24359_38154443.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24387_40954443.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58016154chr19:46190985ENST00000282292+24415_43754443.0Zinc fingerC2H2-type 9
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24191_21353442.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24219_24153442.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24247_26953442.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24275_29753442.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24303_32553442.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24331_35353442.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24359_38153442.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24387_40953442.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58016154chr19:46190985ENST00000598770+24415_43753442.0Zinc fingerC2H2-type 9
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34191_21387443.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34219_24187443.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34247_26987443.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34275_29787443.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34303_32587443.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34331_35387443.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34359_38187443.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34387_40987443.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58016768chr19:46190985ENST00000282292+34415_43787443.0Zinc fingerC2H2-type 9
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34191_21386442.0Zinc fingerC2H2-type 1
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34219_24186442.0Zinc fingerC2H2-type 2
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34247_26986442.0Zinc fingerC2H2-type 3
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34275_29786442.0Zinc fingerC2H2-type 4
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34303_32586442.0Zinc fingerC2H2-type 5
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34331_35386442.0Zinc fingerC2H2-type 6
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34359_38186442.0Zinc fingerC2H2-type 7
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34387_40986442.0Zinc fingerC2H2-type 8
HgeneZNF773chr19:58016768chr19:46190985ENST00000598770+34415_43786442.0Zinc fingerC2H2-type 9


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Fusion Gene Sequence for ZNF773-SNRPD2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102901_102901_1_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000282292_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=577nt_BP=303nt
CGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCCCA
GGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCAGGGCT
ATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATGTGA
TGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGAGGTACCCAAGAG
TGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGTCATCGTGGTCCT
GCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGCTGCCATTGGTGT

>102901_102901_1_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000282292_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=63AA_BP=

--------------------------------------------------------------
>102901_102901_2_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000593916_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=600nt_BP=326nt
ACTCAGCTTGCCGGAAGCTGGTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCG
GGTCTGAGGCTCGGTGGCGGCGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCAC
GCTGAGGGACCCCGCTCAGGGCTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCA
GAGGCTCCTCTACCGCAATGTGATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAG
ATGTGGACTGAGGTACCCAAGAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGC
GGGGACTCAGTCATCGTGGTCCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCT

>102901_102901_2_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000593916_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=87AA_BP=1

--------------------------------------------------------------
>102901_102901_3_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000598770_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=580nt_BP=306nt
GTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGG
CGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGG
GCTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATG
TGATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGAGGTACCCAA
GAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGTCATCGTGGT
CCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGCTGCCATTGG

>102901_102901_3_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000598770_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=64AA_BP=

--------------------------------------------------------------
>102901_102901_4_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000599847_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=579nt_BP=305nt
TTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCC
CAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCAGGG
CTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATGT
GATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGAGGTACCCAAG
AGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGTCATCGTGGTC
CTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGCTGCCATTGGT

>102901_102901_4_ZNF773-SNRPD2_ZNF773_chr19_58016154_ENST00000599847_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=63AA_BP=

--------------------------------------------------------------
>102901_102901_5_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000282292_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=676nt_BP=402nt
CGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCCCA
GGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCAGGGCT
ATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATGTGA
TGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGACTTGCATCTTCCAAGACCCATGAAATAACCCAGCTGGAGTCATGGGAGGAGCCCT
TCATGCCTGCTTGGGAAGTTGTGACTTCAGCCATACTGAGAGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGAGGT
ACCCAAGAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGTCAT
CGTGGTCCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGCTGC

>102901_102901_5_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000282292_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=96AA_BP=
MAAATLRDPAQQGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENFTLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAILRGTA

--------------------------------------------------------------
>102901_102901_6_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000593916_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=699nt_BP=425nt
ACTCAGCTTGCCGGAAGCTGGTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCG
GGTCTGAGGCTCGGTGGCGGCGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCAC
GCTGAGGGACCCCGCTCAGGGCTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCA
GAGGCTCCTCTACCGCAATGTGATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGACTTGCATCTTCCAAGACCCATGAAATAACCCA
GCTGGAGTCATGGGAGGAGCCCTTCATGCCTGCTTGGGAAGTTGTGACTTCAGCCATACTGAGAGGCACTGCAACATGGTGCTGGAGAAC
GTGAAGGAGATGTGGACTGAGGTACCCAAGAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATG
TTCCTGCGCGGGGACTCAGTCATCGTGGTCCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTC

>102901_102901_6_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000593916_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=95AA_BP=
MAAATLRDPAQGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENFTLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAILRGTAT

--------------------------------------------------------------
>102901_102901_7_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000598770_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=679nt_BP=405nt
GTTGTTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGG
CGCCCAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGG
GCTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATG
TGATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGACTTGCATCTTCCAAGACCCATGAAATAACCCAGCTGGAGTCATGGGAGGAGC
CCTTCATGCCTGCTTGGGAAGTTGTGACTTCAGCCATACTGAGAGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGA
GGTACCCAAGAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGT
CATCGTGGTCCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGC

>102901_102901_7_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000598770_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=95AA_BP=
MAAATLRDPAQGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENFTLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAILRGTAT

--------------------------------------------------------------
>102901_102901_8_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000599847_SNRPD2_chr19_46190985_ENST00000342669_length(transcript)=678nt_BP=404nt
TTCGCTGCGGCGACCAGCTCCGGAAAGCGCGGTGGGGACGCGCTGTGTTCTCGCAGCTCAGAGGCGGGTCTGAGGCTCGGTGGCGGCGCC
CAGGGTGGCCCGGGCCCTTTCCTCGGTCGTTGTCTCACCGCCACAGGCTCCGATGGCGGCGGCCACGCTGAGGGACCCCGCTCAGCAGGG
CTATGTGACCTTTGAGGACGTGGCTGTCTACTTCTCCCAGGAGGAATGGAGATTGCTTGATGACGCTCAGAGGCTCCTCTACCGCAATGT
GATGCTGGAGAACTTTACACTTCTGGCCTCTCTGGGACTTGCATCTTCCAAGACCCATGAAATAACCCAGCTGGAGTCATGGGAGGAGCC
CTTCATGCCTGCTTGGGAAGTTGTGACTTCAGCCATACTGAGAGGCACTGCAACATGGTGCTGGAGAACGTGAAGGAGATGTGGACTGAG
GTACCCAAGAGTGGCAAGGGCAAGAAGAAGTCCAAGCCAGTCAACAAAGACCGCTACATCTCCAAGATGTTCCTGCGCGGGGACTCAGTC
ATCGTGGTCCTGCGGAACCCGCTCATCGCCGGCAAGTAGGGGCCGCCTGTCTGTTGACAGAACTCACTCCTCTGTCCTATGAAGACCGCT

>102901_102901_8_ZNF773-SNRPD2_ZNF773_chr19_58016768_ENST00000599847_SNRPD2_chr19_46190985_ENST00000342669_length(amino acids)=96AA_BP=
MAAATLRDPAQQGYVTFEDVAVYFSQEEWRLLDDAQRLLYRNVMLENFTLLASLGLASSKTHEITQLESWEEPFMPAWEVVTSAILRGTA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNF773-SNRPD2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF773-SNRPD2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF773-SNRPD2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource