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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF780A-SAMD4B (FusionGDB2 ID:102916)

Fusion Gene Summary for ZNF780A-SAMD4B

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF780A-SAMD4B
Fusion gene ID: 102916
HgeneTgene
Gene symbol

ZNF780A

SAMD4B

Gene ID

284323

55095

Gene namezinc finger protein 780Asterile alpha motif domain containing 4B
SynonymsZNF780SMGB|Smaug2
Cytomap

19q13.2

19q13.2

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 780Aprotein Smaug homolog 2SAM domain-containing protein 4Bsmaug 2smaug homolog Bsterile alpha motif domain-containing protein 4B
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000340963, ENST00000414720, 
ENST00000450241, ENST00000455521, 
ENST00000594395, ENST00000595687, 
ENST00000594204, ENST00000596368, 
ENST00000314471, ENST00000598913, 
Fusion gene scores* DoF score4 X 4 X 4=647 X 8 X 5=280
# samples 48
** MAII scorelog2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF780A [Title/Abstract] AND SAMD4B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF780A(40587726)-SAMD4B(39860295), # samples:3
Anticipated loss of major functional domain due to fusion event.ZNF780A-SAMD4B seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
ZNF780A-SAMD4B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNF780A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SAMD4B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4MESOTCGA-MQ-A4LP-01AZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+


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Fusion Gene ORF analysis for ZNF780A-SAMD4B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000340963ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000340963ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000414720ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000414720ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000450241ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000450241ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000455521ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000455521ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000594395ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000594395ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000595687ENST00000594204ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
5CDS-intronENST00000595687ENST00000596368ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000340963ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000340963ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000414720ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000414720ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000450241ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000450241ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000455521ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
Frame-shiftENST00000455521ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
In-frameENST00000594395ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
In-frameENST00000594395ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
In-frameENST00000595687ENST00000314471ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+
In-frameENST00000595687ENST00000598913ZNF780Achr19

40587726

-SAMD4Bchr19

39860295

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000595687ZNF780Achr1940587726-ENST00000598913SAMD4Bchr1939860295+2783442542324756
ENST00000595687ZNF780Achr1940587726-ENST00000314471SAMD4Bchr1939860295+3730442542330758
ENST00000594395ZNF780Achr1940587726-ENST00000598913SAMD4Bchr1939860295+2691350252232735
ENST00000594395ZNF780Achr1940587726-ENST00000314471SAMD4Bchr1939860295+3638350252238737

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000595687ENST00000598913ZNF780Achr1940587726-SAMD4Bchr1939860295+0.037278290.9627217
ENST00000595687ENST00000314471ZNF780Achr1940587726-SAMD4Bchr1939860295+0.0089375320.9910624
ENST00000594395ENST00000598913ZNF780Achr1940587726-SAMD4Bchr1939860295+0.0331140760.966886
ENST00000594395ENST00000314471ZNF780Achr1940587726-SAMD4Bchr1939860295+0.006989470.99301046

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Fusion Genomic Features for ZNF780A-SAMD4B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF780Achr1940587725-SAMD4Bchr1939860294+1.30E-091
ZNF780Achr1940587725-SAMD4Bchr1939860294+1.30E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF780A-SAMD4B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:40587726/chr19:39860295)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-676_7777642.0DomainKRAB
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-696_7793720.3333333333334DomainKRAB
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-566_7778643.0DomainKRAB
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-456_7778643.0DomainKRAB
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-566_7777642.0DomainKRAB
TgeneSAMD4Bchr19:40587726chr19:39860295ENST00000314471416299_37265695.0DomainNote=SAM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-566_7743608.0DomainKRAB
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67165_18777642.0Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67193_21577642.0Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67221_24377642.0Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67249_27177642.0Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67277_29977642.0Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67305_32777642.0Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67333_35577642.0Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67361_38377642.0Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67389_41177642.0Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67417_43977642.0Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67445_46777642.0Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67473_49577642.0Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67501_52377642.0Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67529_55177642.0Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67557_57977642.0Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67585_60777642.0Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000340963-67613_63577642.0Zinc fingerC2H2-type 17
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69165_18793720.3333333333334Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69193_21593720.3333333333334Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69221_24393720.3333333333334Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69249_27193720.3333333333334Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69277_29993720.3333333333334Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69305_32793720.3333333333334Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69333_35593720.3333333333334Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69361_38393720.3333333333334Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69389_41193720.3333333333334Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69417_43993720.3333333333334Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69445_46793720.3333333333334Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69473_49593720.3333333333334Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69501_52393720.3333333333334Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69529_55193720.3333333333334Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69557_57993720.3333333333334Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69585_60793720.3333333333334Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000414720-69613_63593720.3333333333334Zinc fingerC2H2-type 17
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56165_18743608.0Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56193_21543608.0Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56221_24343608.0Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56249_27143608.0Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56277_29943608.0Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56305_32743608.0Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56333_35543608.0Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56361_38343608.0Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56389_41143608.0Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56417_43943608.0Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56445_46743608.0Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56473_49543608.0Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56501_52343608.0Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56529_55143608.0Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56557_57943608.0Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56585_60743608.0Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000450241-56613_63543608.0Zinc fingerC2H2-type 17
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56165_18778643.0Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56193_21578643.0Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56221_24378643.0Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56249_27178643.0Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56277_29978643.0Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56305_32778643.0Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56333_35578643.0Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56361_38378643.0Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56389_41178643.0Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56417_43978643.0Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56445_46778643.0Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56473_49578643.0Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56501_52378643.0Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56529_55178643.0Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56557_57978643.0Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56585_60778643.0Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000455521-56613_63578643.0Zinc fingerC2H2-type 17
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45165_18778643.0Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45193_21578643.0Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45221_24378643.0Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45249_27178643.0Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45277_29978643.0Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45305_32778643.0Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45333_35578643.0Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45361_38378643.0Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45389_41178643.0Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45417_43978643.0Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45445_46778643.0Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45473_49578643.0Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45501_52378643.0Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45529_55178643.0Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45557_57978643.0Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45585_60778643.0Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000594395-45613_63578643.0Zinc fingerC2H2-type 17
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56165_18777642.0Zinc fingerC2H2-type 1
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56193_21577642.0Zinc fingerC2H2-type 2
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56221_24377642.0Zinc fingerC2H2-type 3
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56249_27177642.0Zinc fingerC2H2-type 4
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56277_29977642.0Zinc fingerC2H2-type 5
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56305_32777642.0Zinc fingerC2H2-type 6
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56333_35577642.0Zinc fingerC2H2-type 7
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56361_38377642.0Zinc fingerC2H2-type 8
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56389_41177642.0Zinc fingerC2H2-type 9
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56417_43977642.0Zinc fingerC2H2-type 10
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56445_46777642.0Zinc fingerC2H2-type 11
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56473_49577642.0Zinc fingerC2H2-type 12
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56501_52377642.0Zinc fingerC2H2-type 13
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56529_55177642.0Zinc fingerC2H2-type 14
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56557_57977642.0Zinc fingerC2H2-type 15
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56585_60777642.0Zinc fingerC2H2-type 16
HgeneZNF780Achr19:40587726chr19:39860295ENST00000595687-56613_63577642.0Zinc fingerC2H2-type 17


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Fusion Gene Sequence for ZNF780A-SAMD4B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>102916_102916_1_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000594395_SAMD4B_chr19_39860295_ENST00000314471_length(transcript)=3638nt_BP=350nt
TCGTATTTTTATCCAAAAGAAGGACCTGGAGGAGGATGAGAGCGTTACTGCTGCACACCTAAAGTCAAGGGGGAGAAGCCCGAGGAAGAT
TGACCAGTTTTGTAATTCTAGCAACATGGTCCATGGATCAGTGACATTCAGGGATGTGGCCATTGACTTCTCTCAGGAGGAGTGGGAGTG
CCTGCAGCCTGATCAGAGGACCTTGTACAGGGATGTGATGTTGGAGAACTACAGCCACCTGATCTCACTGGCAGGAAGTTCCATTTCTAA
ACCAGATGTAATTACGTTACTAGAGCAAGAGAAAGAGCCCTGGATGGTTGTAAGGAAAGAAACAAGCAGACGGTATCCAGCCATCGTCAG
CCAGTGGCAGCAGGAGTCCAAAGAGAAGGTGGTGTCCCTCCTGCTGTCCCACCTTCCCCTGCTTCAGCCAGGCAACACAGAGGCCAAGTC
GGAGTACATGAGGCTACTGCAGAAAGTGCTGGCCTACTCAATCGAGAGCAATGCTTTCATCGAGGAGAGTCGCCAGCTGCTTTCCTATGC
CCTCATCCACCCAGCCACCACACTGGAGGACCGCAACGCACTGGCCCTCTGGCTGAGCCACCTGGAAGAGCGGTTGGCTAGTGGCTTCCG
CTCCCGGCCAGAGCCCTCCTACCATTCACGTCAAGGCTCAGATGAGTGGGGGGGCCCTGCAGAGCTAGGCCCTGGGGAGGCAGGGCCAGG
CTGGCAGGACAAGCCACCCCGGGAAAATGGACACGTGCCCTTCCACCCATCCAGCTCAGTGCCGCCAGCCATCAACAGTATTGGGAGCAA
TGCAAACACAGGTCTCCCCTGCCAAATCCACCCTAGCCCACTGAAGCGCTCCATGTCACTCATCCCTACAAGCCCCCAGGTCCCTGGTGA
GTGGCCGAGTCCAGAGGAGCTTGGGGCCCGGGCTGCTTTTACCACGCCCGATCACGCACCTCTCTCGCCCCAGAGCAGCGTGGCCTCCTC
TGGCAGTGAGCAGACAGAGGAGCAGGGCTCCAGCCGGAACACCTTCCAGGAGGATGGCAGTGGCATGAAAGATGTGCCCTCATGGCTCAA
GAGCCTCCGTTTGCACAAGTATGCAGCCCTCTTCTCACAGATGAGCTACGAGGAGATGATGACACTGACTGAGCAGCACCTGGAGTCTCA
GAACGTCACCAAAGGTGCCCGCCACAAGATAGCCCTGAGCATCCAGAAGCTGCGTGAGAGACAGAGCGTCCTCAAGTCCCTAGAGAAGGA
TGTGCTGGAAGGCGGGAACCTACGAAACGCTCTGCAGGAGCTGCAGCAGATCATCATCACTCCCATCAAGGCCTACAGTGTCCTCCAGGC
CACCGTGGCTGCCGCCACCACCACCCCTACTGCCAAGGATGGGGCCCCGGGGGAACCACCGCTGCCAGGTGCTGAGCCTCCCCTAGCCCA
CCCCGGCACAGACAAAGGCACCGAGGCCAAGGACCCTCCAGCTGTGGAGAACTACCCACCTCCACCAGCTCCAGCTCCCACTGATGGCAG
TGAGCCTGCCCCGGCTCCCGTCGCCGACGGAGACATCCCCAGCCAGTTTACACGGGTGATGGGCAAAGTGTGCACCCAACTGCTGGTGTC
CCGACCAGACGAGGAGAACATCACCAGTTACCTCCAGCTCATCGAAAAGTGCCTGACTCATGAGGCTTTCACGGAGACGCAGAAGAAACG
GCTGCTATCCTGGAAACAGCAAGTGCTGAAGCTCCTCCGGACATTCCCGCGCAAAGCCGCACTAGAGATGCAGAACTACCGGCAGCAGAA
AGGCTGGGCATTCGGCTCCAACTCGCTCCCCATAGCTGGCTCTGTGGGGATGGGAGTGGCCCGGCGTACCCAGCGGCAGTTCCCAATGCC
TCCCCGGGCCCTCCCACCCGGCCGGATGGGCCTCCTGAGCCCCTCGGGCATTGGGGGTGTCTCCCCTCGACATGCCCTCACCAGCCCCAG
CCTTGGAGGCCAGGGCCGACAGAACCTGTGGTTTGCCAACCCTGGAGGCAGCAACAGCATGCCCAGTCAGAGCCGCAGCTCTGTGCAGCG
CACCCACTCGCTCCCGGTCCACTCGTCACCCCAGGCCATTCTCATGTTCCCTCCAGACTGCCCGGTTCCTGGGCCTGACCTGGAGATCAA
TCCCACTCTGGAGTCTCTGTGTCTGAGCATGACAGAACACGCCTTGGGTGATGGGACAGACAAAACCTCCACCATCTGACGGGACCCACA
GCCCAGCGCACCCATAGGCTCCCTGGGCGGCGGGCGGGGGCCAACCCCCAACGGGCTTCTCCGCGACAGCGAGAGGGTGGGCTGGCTCAG
CTATATATTCTAATATTTTTCTACTCTCTTACCCTCTTAACTTTTGTTTAACATTGGCACATGCCTTGCTCACTCCCAGGCCCGTCGAGG
GATCTCTGCTGAGGCCCGGGGAGTTGGGGGCAGCCAGGATAAAGGGGGCAGGGACTGGCCAGACTGCCTGCCTCTCTCCTTTCCTTCCTC
ATCCCCACCTGGTCCCATCCCACCCCTGCCTCCTCCAGACCGCTGACCACCTGCCTCTCCCCAAGGGAGCAGACTCCCCAGAGACAAACT
GACCACTACCTTGTGGAGCCTGCTCAGAAACATTTGACATTTGGGGTGACGCGCAGGGCAGAGAACCTGCCCTCCAGAATGTTATTGAGA
GGAGCTGGGGAGAAGGAAGGGGAGCAAGGAGAGGAAGCTCTCTCTCCTCTCCCTGCTTCCCCTTCACCATTCCCCACATTCTGCAAGGAC
AGGAGCCACCTTCCTCTCTCTCACCTCCCCTGGCCCTGTTCACCAGAGGTTCTCTATGATTAATTTCTTAGGCCTATTTAAGATACATAT
TTATATAGTTCTTAACGGTTTTTCTCTGATCATTTCCTCTCATTTTTAGAATCCCCAGGTCTCTCTCAGCCAAGACAGTGGCAGGGAGAG
CCTGAACTTTATGAGGGGAGAGGGCAGAGCCCCCTCCTCCAGACCCTCAAGCTCTAACCCATTTTCCTCCAGCCCTGGCTACCCGGATGA
AGAGGTTGGAGGTGGGCAGCCAGGGTAGCCAGTGAGGTCAGGAAGTCTGTTGCCTTAACGTCCCCTTCCCCACGAACACACACCCTTCTC
CGCTCCCAGGTCTGGTTGGTGAGACTTGGGAGTCAGGAATAAGGGAAAGGGGATTGTTTGGTTTTTGGGTTTTTCCCTAAGCCCCTCCCT
TTTCTTTCAGCCTTTTTCCTTCCCCCATTATGTCATGACCTCACTTAAGTGGAACACTATATCATAACCCAGAGATTCGTCCCAGCCCCA
GAGTCCGACAGACTGTCTGGTCCCTATTCCTAATGAGGGGTTGTGTTGGGGCCCAGGTGGAGGGAGGGGATTTGGGGGTTCAGACTGCGG
GGAAGCCAGGGTCTCCCTCTTCAACGCCCTCCTCCCCCTCAACCCACCTTCCCAACTGGGACATTCTCAAGCTTTTCACACCGAAAAGGA
AAAAAAATGTTATTTTTAGATACATTTTATGAATAACTTTTGTTATGAATATGGCTGGTAACCATTGTGTATGTTATTAAAGATACAAAA

>102916_102916_1_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000594395_SAMD4B_chr19_39860295_ENST00000314471_length(amino acids)=737AA_BP=108
MEEDESVTAAHLKSRGRSPRKIDQFCNSSNMVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLISLAGSSISKPDVITLLE
QEKEPWMVVRKETSRRYPAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTL
EDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQ
IHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYA
ALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTT
PTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENIT
SYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGR
MGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCL

--------------------------------------------------------------
>102916_102916_2_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000594395_SAMD4B_chr19_39860295_ENST00000598913_length(transcript)=2691nt_BP=350nt
TCGTATTTTTATCCAAAAGAAGGACCTGGAGGAGGATGAGAGCGTTACTGCTGCACACCTAAAGTCAAGGGGGAGAAGCCCGAGGAAGAT
TGACCAGTTTTGTAATTCTAGCAACATGGTCCATGGATCAGTGACATTCAGGGATGTGGCCATTGACTTCTCTCAGGAGGAGTGGGAGTG
CCTGCAGCCTGATCAGAGGACCTTGTACAGGGATGTGATGTTGGAGAACTACAGCCACCTGATCTCACTGGCAGGAAGTTCCATTTCTAA
ACCAGATGTAATTACGTTACTAGAGCAAGAGAAAGAGCCCTGGATGGTTGTAAGGAAAGAAACAAGCAGACGGTATCCAGCCATCGTCAG
CCAGTGGCAGCAGGAGTCCAAAGAGAAGGTGGTGTCCCTCCTGCTGTCCCACCTTCCCCTGCTTCAGCCAGGCAACACAGAGGCCAAGTC
GGAGTACATGAGGCTACTGCAGAAAGTGCTGGCCTACTCAATCGAGAGCAATGCTTTCATCGAGGAGAGTCGCCAGCTGCTTTCCTATGC
CCTCATCCACCCAGCCACCACACTGGAGGACCGCAACGCACTGGCCCTCTGGCTGAGCCACCTGGAAGAGCGGTTGGCTAGTGGCTTCCG
CTCCCGGCCAGAGCCCTCCTACCATTCACGTCAAGGCTCAGATGAGTGGGGGGGCCCTGCAGAGCTAGGCCCTGGGGAGGCAGGGCCAGG
CTGGCAGGACAAGCCACCCCGGGAAAATGGACACGTGCCCTTCCACCCATCCAGCTCAGTGCCGCCAGCCATCAACAGTATTGGGAGCAA
TGCAAACACAGGTCTCCCCTGCCAAATCCACCCTAGCCCACTGAAGCGCTCCATGTCACTCATCCCTACAAGCCCCCAGGTCCCTGGTGA
GTGGCCGAGTCCAGAGGAGCTTGGGGCCCGGGCTGCTTTTACCACGCCCGATCACGCACCTCTCTCGCCCCAGAGCAGCGTGGCCTCCTC
TGGCAGTGAGCAGACAGAGGAGCAGGGCTCCAGCCGGAACACCTTCCAGGAGGATGGCAGTGGCATGAAAGATGTGCCCTCATGGCTCAA
GAGCCTCCGTTTGCACAAGTATGCAGCCCTCTTCTCACAGATGAGCTACGAGGAGATGATGACACTGACTGAGCAGCACCTGGAGTCTCA
GAACGTCACCAAAGGTGCCCGCCACAAGATAGCCCTGAGCATCCAGAAGCTGCGTGAGAGACAGAGCGTCCTCAAGTCCCTAGAGAAGGA
TGTGCTGGAAGGCGGGAACCTACGAAACGCTCTGCAGGAGCTGCAGCAGATCATCATCACTCCCATCAAGGCCTACAGTGTCCTCCAGGC
CACCGTGGCTGCCGCCACCACCACCCCTACTGCCAAGGATGGGGCCCCGGGGGAACCACCGCTGCCAGGTGCTGAGCCTCCCCTAGCCCA
CCCCGGCACAGACAAAGGCACCGAGGCCAAGGACCCTCCAGCTGTGGAGAACTACCCACCTCCACCAGCTCCAGCTCCCACTGATGGCAG
TGAGCCTGCCCCGGCTCCCGTCGCCGACGGAGACATCCCCAGCCAGTTTACACGGGTGATGGGCAAAGTGTGCACCCAACTGCTGGTGTC
CCGACCAGACGAGGAGAACATCACCAGTTACCTCCAGCTCATCGAAAAGTGCCTGACTCATGAGGCTTTCACGGAGACGCAGAAGAAACG
GCTGCTATCCTGGAAACAGCAAGTGCTGAAGCTCCTCCGGACATTCCCGCGCAAAGCCGCACTAGAGATGCAGAACTACCGGCAGCAGAA
AGGCTGGGCATTCGGCTCCAACTCGCTCCCCATAGCTGGCTCTGTGGGGATGGGAGTGGCCCGGCGTACCCAGCGGCAGTTCCCAATGCC
TCCCCGGGCCCTCCCACCCGGCCGGATGGGCCTCCTGAGCCCCTCGGGCATTGGGGGTGTCTCCCCTCGACATGCCCTCACCAGCCCCAG
CCTTGGAGGCCAGGGCCGACAGAACCTGTGGTTTGCCAACCCTGGAGGCAGCAACAGCATGCCCAGTCAGAGCCGCAGCTCTGTGCAGCG
CACCCACTCGCTCCCGGTCCACTCGTCACCCCAGGCCATTCTCATGTTCCCTCCAGACTGCCCGGTTCCTGGGCCTGACCTGGAGATCAA
TCCCACTCTGGAGTCTCTGTGTCTGAGCATGACAGAACACGCCTTGGGTGGCCCGTCGAGGGATCTCTGCTGAGGCCCGGGGAGTTGGGG
GCAGCCAGGATAAAGGGGGCAGGGACTGGCCAGACTGCCTGCCTCTCTCCTTTCCTTCCTCATCCCCACCTGGTCCCATCCCACCCCTGC
CTCCTCCAGACCGCTGACCACCTGCCTCTCCCCAAGGGAGCAGACTCCCCAGAGACAAACTGACCACTACCTTGTGGAGCCTGCTCAGAA
ACATTTGACATTTGGGGTGACGCGCAGGGCAGAGAACCTGCCCTCCAGAATGTTATTGAGAGGAGCTGGGGAGAAGGAAGGGGAGCAAGG
AGAGGAAGCTCTCTCTCCTCTCCCTGCTTCCCCTTCACCATTCCCCACATTCTGCAAGGACAGGAGCCACCTTCCTCTCTCTCACCTCCC

>102916_102916_2_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000594395_SAMD4B_chr19_39860295_ENST00000598913_length(amino acids)=735AA_BP=108
MEEDESVTAAHLKSRGRSPRKIDQFCNSSNMVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLISLAGSSISKPDVITLLE
QEKEPWMVVRKETSRRYPAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESNAFIEESRQLLSYALIHPATTL
EDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPSSSVPPAINSIGSNANTGLPCQ
IHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQEDGSGMKDVPSWLKSLRLHKYA
ALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQIIITPIKAYSVLQATVAAATTT
PTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFTRVMGKVCTQLLVSRPDEENIT
SYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGMGVARRTQRQFPMPPRALPPGR
MGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFPPDCPVPGPDLEINPTLESLCL

--------------------------------------------------------------
>102916_102916_3_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000595687_SAMD4B_chr19_39860295_ENST00000314471_length(transcript)=3730nt_BP=442nt
GAGGAAGAGATCTGTGGCTGCGGGAGATCTCTGCGGATTGGGGCTCCAGCCTGACTGACCCGACAGTGCGGGTGGCCTAGGGGGAGGCGC
TCAGATCGTATTTTTATCCAAAAGAAGGACCTGGAGGAGGATGAGAGCGTTACTGCTGCACACCTAAAGTCAAGGGGGAGAAGCCCGAGG
AAGATTGACCAGTTTTGTAATTCTAGCAACATGGTCCATGGATCAGTGACATTCAGGGATGTGGCCATTGACTTCTCTCAGGAGGAGTGG
GAGTGCCTGCAGCCTGATCAGAGGACCTTGTACAGGGATGTGATGTTGGAGAACTACAGCCACCTGATCTCACTGGGAAGTTCCATTTCT
AAACCAGATGTAATTACGTTACTAGAGCAAGAGAAAGAGCCCTGGATGGTTGTAAGGAAAGAAACAAGCAGACGGTATCCAGCCATCGTC
AGCCAGTGGCAGCAGGAGTCCAAAGAGAAGGTGGTGTCCCTCCTGCTGTCCCACCTTCCCCTGCTTCAGCCAGGCAACACAGAGGCCAAG
TCGGAGTACATGAGGCTACTGCAGAAAGTGCTGGCCTACTCAATCGAGAGCAATGCTTTCATCGAGGAGAGTCGCCAGCTGCTTTCCTAT
GCCCTCATCCACCCAGCCACCACACTGGAGGACCGCAACGCACTGGCCCTCTGGCTGAGCCACCTGGAAGAGCGGTTGGCTAGTGGCTTC
CGCTCCCGGCCAGAGCCCTCCTACCATTCACGTCAAGGCTCAGATGAGTGGGGGGGCCCTGCAGAGCTAGGCCCTGGGGAGGCAGGGCCA
GGCTGGCAGGACAAGCCACCCCGGGAAAATGGACACGTGCCCTTCCACCCATCCAGCTCAGTGCCGCCAGCCATCAACAGTATTGGGAGC
AATGCAAACACAGGTCTCCCCTGCCAAATCCACCCTAGCCCACTGAAGCGCTCCATGTCACTCATCCCTACAAGCCCCCAGGTCCCTGGT
GAGTGGCCGAGTCCAGAGGAGCTTGGGGCCCGGGCTGCTTTTACCACGCCCGATCACGCACCTCTCTCGCCCCAGAGCAGCGTGGCCTCC
TCTGGCAGTGAGCAGACAGAGGAGCAGGGCTCCAGCCGGAACACCTTCCAGGAGGATGGCAGTGGCATGAAAGATGTGCCCTCATGGCTC
AAGAGCCTCCGTTTGCACAAGTATGCAGCCCTCTTCTCACAGATGAGCTACGAGGAGATGATGACACTGACTGAGCAGCACCTGGAGTCT
CAGAACGTCACCAAAGGTGCCCGCCACAAGATAGCCCTGAGCATCCAGAAGCTGCGTGAGAGACAGAGCGTCCTCAAGTCCCTAGAGAAG
GATGTGCTGGAAGGCGGGAACCTACGAAACGCTCTGCAGGAGCTGCAGCAGATCATCATCACTCCCATCAAGGCCTACAGTGTCCTCCAG
GCCACCGTGGCTGCCGCCACCACCACCCCTACTGCCAAGGATGGGGCCCCGGGGGAACCACCGCTGCCAGGTGCTGAGCCTCCCCTAGCC
CACCCCGGCACAGACAAAGGCACCGAGGCCAAGGACCCTCCAGCTGTGGAGAACTACCCACCTCCACCAGCTCCAGCTCCCACTGATGGC
AGTGAGCCTGCCCCGGCTCCCGTCGCCGACGGAGACATCCCCAGCCAGTTTACACGGGTGATGGGCAAAGTGTGCACCCAACTGCTGGTG
TCCCGACCAGACGAGGAGAACATCACCAGTTACCTCCAGCTCATCGAAAAGTGCCTGACTCATGAGGCTTTCACGGAGACGCAGAAGAAA
CGGCTGCTATCCTGGAAACAGCAAGTGCTGAAGCTCCTCCGGACATTCCCGCGCAAAGCCGCACTAGAGATGCAGAACTACCGGCAGCAG
AAAGGCTGGGCATTCGGCTCCAACTCGCTCCCCATAGCTGGCTCTGTGGGGATGGGAGTGGCCCGGCGTACCCAGCGGCAGTTCCCAATG
CCTCCCCGGGCCCTCCCACCCGGCCGGATGGGCCTCCTGAGCCCCTCGGGCATTGGGGGTGTCTCCCCTCGACATGCCCTCACCAGCCCC
AGCCTTGGAGGCCAGGGCCGACAGAACCTGTGGTTTGCCAACCCTGGAGGCAGCAACAGCATGCCCAGTCAGAGCCGCAGCTCTGTGCAG
CGCACCCACTCGCTCCCGGTCCACTCGTCACCCCAGGCCATTCTCATGTTCCCTCCAGACTGCCCGGTTCCTGGGCCTGACCTGGAGATC
AATCCCACTCTGGAGTCTCTGTGTCTGAGCATGACAGAACACGCCTTGGGTGATGGGACAGACAAAACCTCCACCATCTGACGGGACCCA
CAGCCCAGCGCACCCATAGGCTCCCTGGGCGGCGGGCGGGGGCCAACCCCCAACGGGCTTCTCCGCGACAGCGAGAGGGTGGGCTGGCTC
AGCTATATATTCTAATATTTTTCTACTCTCTTACCCTCTTAACTTTTGTTTAACATTGGCACATGCCTTGCTCACTCCCAGGCCCGTCGA
GGGATCTCTGCTGAGGCCCGGGGAGTTGGGGGCAGCCAGGATAAAGGGGGCAGGGACTGGCCAGACTGCCTGCCTCTCTCCTTTCCTTCC
TCATCCCCACCTGGTCCCATCCCACCCCTGCCTCCTCCAGACCGCTGACCACCTGCCTCTCCCCAAGGGAGCAGACTCCCCAGAGACAAA
CTGACCACTACCTTGTGGAGCCTGCTCAGAAACATTTGACATTTGGGGTGACGCGCAGGGCAGAGAACCTGCCCTCCAGAATGTTATTGA
GAGGAGCTGGGGAGAAGGAAGGGGAGCAAGGAGAGGAAGCTCTCTCTCCTCTCCCTGCTTCCCCTTCACCATTCCCCACATTCTGCAAGG
ACAGGAGCCACCTTCCTCTCTCTCACCTCCCCTGGCCCTGTTCACCAGAGGTTCTCTATGATTAATTTCTTAGGCCTATTTAAGATACAT
ATTTATATAGTTCTTAACGGTTTTTCTCTGATCATTTCCTCTCATTTTTAGAATCCCCAGGTCTCTCTCAGCCAAGACAGTGGCAGGGAG
AGCCTGAACTTTATGAGGGGAGAGGGCAGAGCCCCCTCCTCCAGACCCTCAAGCTCTAACCCATTTTCCTCCAGCCCTGGCTACCCGGAT
GAAGAGGTTGGAGGTGGGCAGCCAGGGTAGCCAGTGAGGTCAGGAAGTCTGTTGCCTTAACGTCCCCTTCCCCACGAACACACACCCTTC
TCCGCTCCCAGGTCTGGTTGGTGAGACTTGGGAGTCAGGAATAAGGGAAAGGGGATTGTTTGGTTTTTGGGTTTTTCCCTAAGCCCCTCC
CTTTTCTTTCAGCCTTTTTCCTTCCCCCATTATGTCATGACCTCACTTAAGTGGAACACTATATCATAACCCAGAGATTCGTCCCAGCCC
CAGAGTCCGACAGACTGTCTGGTCCCTATTCCTAATGAGGGGTTGTGTTGGGGCCCAGGTGGAGGGAGGGGATTTGGGGGTTCAGACTGC
GGGGAAGCCAGGGTCTCCCTCTTCAACGCCCTCCTCCCCCTCAACCCACCTTCCCAACTGGGACATTCTCAAGCTTTTCACACCGAAAAG
GAAAAAAAATGTTATTTTTAGATACATTTTATGAATAACTTTTGTTATGAATATGGCTGGTAACCATTGTGTATGTTATTAAAGATACAA

>102916_102916_3_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000595687_SAMD4B_chr19_39860295_ENST00000314471_length(amino acids)=758AA_BP=129
MTRQCGWPRGRRSDRIFIQKKDLEEDESVTAAHLKSRGRSPRKIDQFCNSSNMVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLEN
YSHLISLGSSISKPDVITLLEQEKEPWMVVRKETSRRYPAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESN
AFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPS
SSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQE
DGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQI
IITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFT
RVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGM
GVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFP

--------------------------------------------------------------
>102916_102916_4_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000595687_SAMD4B_chr19_39860295_ENST00000598913_length(transcript)=2783nt_BP=442nt
GAGGAAGAGATCTGTGGCTGCGGGAGATCTCTGCGGATTGGGGCTCCAGCCTGACTGACCCGACAGTGCGGGTGGCCTAGGGGGAGGCGC
TCAGATCGTATTTTTATCCAAAAGAAGGACCTGGAGGAGGATGAGAGCGTTACTGCTGCACACCTAAAGTCAAGGGGGAGAAGCCCGAGG
AAGATTGACCAGTTTTGTAATTCTAGCAACATGGTCCATGGATCAGTGACATTCAGGGATGTGGCCATTGACTTCTCTCAGGAGGAGTGG
GAGTGCCTGCAGCCTGATCAGAGGACCTTGTACAGGGATGTGATGTTGGAGAACTACAGCCACCTGATCTCACTGGGAAGTTCCATTTCT
AAACCAGATGTAATTACGTTACTAGAGCAAGAGAAAGAGCCCTGGATGGTTGTAAGGAAAGAAACAAGCAGACGGTATCCAGCCATCGTC
AGCCAGTGGCAGCAGGAGTCCAAAGAGAAGGTGGTGTCCCTCCTGCTGTCCCACCTTCCCCTGCTTCAGCCAGGCAACACAGAGGCCAAG
TCGGAGTACATGAGGCTACTGCAGAAAGTGCTGGCCTACTCAATCGAGAGCAATGCTTTCATCGAGGAGAGTCGCCAGCTGCTTTCCTAT
GCCCTCATCCACCCAGCCACCACACTGGAGGACCGCAACGCACTGGCCCTCTGGCTGAGCCACCTGGAAGAGCGGTTGGCTAGTGGCTTC
CGCTCCCGGCCAGAGCCCTCCTACCATTCACGTCAAGGCTCAGATGAGTGGGGGGGCCCTGCAGAGCTAGGCCCTGGGGAGGCAGGGCCA
GGCTGGCAGGACAAGCCACCCCGGGAAAATGGACACGTGCCCTTCCACCCATCCAGCTCAGTGCCGCCAGCCATCAACAGTATTGGGAGC
AATGCAAACACAGGTCTCCCCTGCCAAATCCACCCTAGCCCACTGAAGCGCTCCATGTCACTCATCCCTACAAGCCCCCAGGTCCCTGGT
GAGTGGCCGAGTCCAGAGGAGCTTGGGGCCCGGGCTGCTTTTACCACGCCCGATCACGCACCTCTCTCGCCCCAGAGCAGCGTGGCCTCC
TCTGGCAGTGAGCAGACAGAGGAGCAGGGCTCCAGCCGGAACACCTTCCAGGAGGATGGCAGTGGCATGAAAGATGTGCCCTCATGGCTC
AAGAGCCTCCGTTTGCACAAGTATGCAGCCCTCTTCTCACAGATGAGCTACGAGGAGATGATGACACTGACTGAGCAGCACCTGGAGTCT
CAGAACGTCACCAAAGGTGCCCGCCACAAGATAGCCCTGAGCATCCAGAAGCTGCGTGAGAGACAGAGCGTCCTCAAGTCCCTAGAGAAG
GATGTGCTGGAAGGCGGGAACCTACGAAACGCTCTGCAGGAGCTGCAGCAGATCATCATCACTCCCATCAAGGCCTACAGTGTCCTCCAG
GCCACCGTGGCTGCCGCCACCACCACCCCTACTGCCAAGGATGGGGCCCCGGGGGAACCACCGCTGCCAGGTGCTGAGCCTCCCCTAGCC
CACCCCGGCACAGACAAAGGCACCGAGGCCAAGGACCCTCCAGCTGTGGAGAACTACCCACCTCCACCAGCTCCAGCTCCCACTGATGGC
AGTGAGCCTGCCCCGGCTCCCGTCGCCGACGGAGACATCCCCAGCCAGTTTACACGGGTGATGGGCAAAGTGTGCACCCAACTGCTGGTG
TCCCGACCAGACGAGGAGAACATCACCAGTTACCTCCAGCTCATCGAAAAGTGCCTGACTCATGAGGCTTTCACGGAGACGCAGAAGAAA
CGGCTGCTATCCTGGAAACAGCAAGTGCTGAAGCTCCTCCGGACATTCCCGCGCAAAGCCGCACTAGAGATGCAGAACTACCGGCAGCAG
AAAGGCTGGGCATTCGGCTCCAACTCGCTCCCCATAGCTGGCTCTGTGGGGATGGGAGTGGCCCGGCGTACCCAGCGGCAGTTCCCAATG
CCTCCCCGGGCCCTCCCACCCGGCCGGATGGGCCTCCTGAGCCCCTCGGGCATTGGGGGTGTCTCCCCTCGACATGCCCTCACCAGCCCC
AGCCTTGGAGGCCAGGGCCGACAGAACCTGTGGTTTGCCAACCCTGGAGGCAGCAACAGCATGCCCAGTCAGAGCCGCAGCTCTGTGCAG
CGCACCCACTCGCTCCCGGTCCACTCGTCACCCCAGGCCATTCTCATGTTCCCTCCAGACTGCCCGGTTCCTGGGCCTGACCTGGAGATC
AATCCCACTCTGGAGTCTCTGTGTCTGAGCATGACAGAACACGCCTTGGGTGGCCCGTCGAGGGATCTCTGCTGAGGCCCGGGGAGTTGG
GGGCAGCCAGGATAAAGGGGGCAGGGACTGGCCAGACTGCCTGCCTCTCTCCTTTCCTTCCTCATCCCCACCTGGTCCCATCCCACCCCT
GCCTCCTCCAGACCGCTGACCACCTGCCTCTCCCCAAGGGAGCAGACTCCCCAGAGACAAACTGACCACTACCTTGTGGAGCCTGCTCAG
AAACATTTGACATTTGGGGTGACGCGCAGGGCAGAGAACCTGCCCTCCAGAATGTTATTGAGAGGAGCTGGGGAGAAGGAAGGGGAGCAA
GGAGAGGAAGCTCTCTCTCCTCTCCCTGCTTCCCCTTCACCATTCCCCACATTCTGCAAGGACAGGAGCCACCTTCCTCTCTCTCACCTC

>102916_102916_4_ZNF780A-SAMD4B_ZNF780A_chr19_40587726_ENST00000595687_SAMD4B_chr19_39860295_ENST00000598913_length(amino acids)=756AA_BP=129
MTRQCGWPRGRRSDRIFIQKKDLEEDESVTAAHLKSRGRSPRKIDQFCNSSNMVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLEN
YSHLISLGSSISKPDVITLLEQEKEPWMVVRKETSRRYPAIVSQWQQESKEKVVSLLLSHLPLLQPGNTEAKSEYMRLLQKVLAYSIESN
AFIEESRQLLSYALIHPATTLEDRNALALWLSHLEERLASGFRSRPEPSYHSRQGSDEWGGPAELGPGEAGPGWQDKPPRENGHVPFHPS
SSVPPAINSIGSNANTGLPCQIHPSPLKRSMSLIPTSPQVPGEWPSPEELGARAAFTTPDHAPLSPQSSVASSGSEQTEEQGSSRNTFQE
DGSGMKDVPSWLKSLRLHKYAALFSQMSYEEMMTLTEQHLESQNVTKGARHKIALSIQKLRERQSVLKSLEKDVLEGGNLRNALQELQQI
IITPIKAYSVLQATVAAATTTPTAKDGAPGEPPLPGAEPPLAHPGTDKGTEAKDPPAVENYPPPPAPAPTDGSEPAPAPVADGDIPSQFT
RVMGKVCTQLLVSRPDEENITSYLQLIEKCLTHEAFTETQKKRLLSWKQQVLKLLRTFPRKAALEMQNYRQQKGWAFGSNSLPIAGSVGM
GVARRTQRQFPMPPRALPPGRMGLLSPSGIGGVSPRHALTSPSLGGQGRQNLWFANPGGSNSMPSQSRSSVQRTHSLPVHSSPQAILMFP

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Fusion Gene PPI Analysis for ZNF780A-SAMD4B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF780A-SAMD4B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF780A-SAMD4B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource