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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNF814-EIF3B (FusionGDB2 ID:103004)

Fusion Gene Summary for ZNF814-EIF3B

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNF814-EIF3B
Fusion gene ID: 103004
HgeneTgene
Gene symbol

ZNF814

EIF3B

Gene ID

730051

8662

Gene namezinc finger protein 814eukaryotic translation initiation factor 3 subunit B
Synonyms-EIF3-ETA|EIF3-P110|EIF3-P116|EIF3S9|PRT1
Cytomap

19q13.43

7p22.3

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein 814eukaryotic translation initiation factor 3 subunit Beukaryotic translation initiation factor 3 subunit 9eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD)eukaryotic translation initiation factor 3, subunit 9 eta, 116kDaprt1 homolog
Modification date2020031320200322
UniProtAcc.

P55884

Ensembl transtripts involved in fusion geneENST00000435989, ENST00000595295, 
ENST00000596604, ENST00000597342, 
ENST00000597807, ENST00000597832, 
ENST00000600634, ENST00000597652, 
ENST00000360876, ENST00000397011, 
Fusion gene scores* DoF score6 X 5 X 4=12016 X 22 X 8=2816
# samples 722
** MAII scorelog2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/2816*10)=-3.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNF814 [Title/Abstract] AND EIF3B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNF814(58400135)-EIF3B(2416585), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF3B

GO:0006413

translational initiation

8995410|17581632

TgeneEIF3B

GO:0006446

regulation of translational initiation

8995410

TgeneEIF3B

GO:0075522

IRES-dependent viral translational initiation

9573242

TgeneEIF3B

GO:0075525

viral translational termination-reinitiation

21347434


check buttonFusion gene breakpoints across ZNF814 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF3B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-FS-A1ZK-06AZNF814chr19

58400135

-EIF3Bchr7

2416585

+


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Fusion Gene ORF analysis for ZNF814-EIF3B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000435989ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000435989ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000595295ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000595295ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000596604ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000596604ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597342ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597342ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597807ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597807ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597832ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000597832ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000600634ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
In-frameENST00000600634ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
intron-3CDSENST00000597652ENST00000360876ZNF814chr19

58400135

-EIF3Bchr7

2416585

+
intron-3CDSENST00000597652ENST00000397011ZNF814chr19

58400135

-EIF3Bchr7

2416585

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000596604ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+112515434570178
ENST00000596604ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+105215434570178
ENST00000597342ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+116319236608190
ENST00000597342ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+109019236608190
ENST00000597832ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+122425397669190
ENST00000597832ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+115125397669190
ENST00000595295ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+102655967446173
ENST00000595295ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+9535519471150
ENST00000600634ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+102251963442173
ENST00000600634ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+9495115467150
ENST00000435989ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+1242271115687190
ENST00000435989ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+1169271115687190
ENST00000597807ZNF814chr1958400135-ENST00000360876EIF3Bchr72416585+117420347619190
ENST00000597807ZNF814chr1958400135-ENST00000397011EIF3Bchr72416585+110120347619190

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000596604ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0052361010.99476385
ENST00000596604ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.005737130.9942629
ENST00000597342ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0058002270.99419975
ENST00000597342ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0051923030.99480766
ENST00000597832ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0049013110.99509865
ENST00000597832ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0046593190.9953407
ENST00000595295ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0043323330.9956677
ENST00000595295ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0041422410.9958578
ENST00000600634ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0044239150.99557614
ENST00000600634ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0045214770.9954786
ENST00000435989ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.0038481080.99615186
ENST00000435989ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0046927480.99530727
ENST00000597807ENST00000360876ZNF814chr1958400135-EIF3Bchr72416585+0.006028460.9939715
ENST00000597807ENST00000397011ZNF814chr1958400135-EIF3Bchr72416585+0.0069877260.99301225

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Fusion Genomic Features for ZNF814-EIF3B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNF814chr1958400134-EIF3Bchr72416584+6.01E-091
ZNF814chr1958400134-EIF3Bchr72416584+6.01E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNF814-EIF3B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:58400135/chr7:2416585)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF3B

P55884

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03001, ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815, ECO:0000269|PubMed:9388245}.; FUNCTION: (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426). {ECO:0000269|PubMed:18056426}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-1315_9112856.0DomainKRAB
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13120_14212856.0Zinc fingerC2H2-type 1%3B degenerate
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13242_26412856.0Zinc fingerC2H2-type 2
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13269_29112856.0Zinc fingerC2H2-type 3
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13296_31812856.0Zinc fingerC2H2-type 4
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13324_34612856.0Zinc fingerC2H2-type 5
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13352_37412856.0Zinc fingerC2H2-type 6
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13380_40212856.0Zinc fingerC2H2-type 7
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13408_43012856.0Zinc fingerC2H2-type 8
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13436_45812856.0Zinc fingerC2H2-type 9
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13464_48612856.0Zinc fingerC2H2-type 10
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13492_51412856.0Zinc fingerC2H2-type 11
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13520_54212856.0Zinc fingerC2H2-type 12
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13548_57012856.0Zinc fingerC2H2-type 13
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13576_59812856.0Zinc fingerC2H2-type 14
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13604_62612856.0Zinc fingerC2H2-type 15
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13632_65412856.0Zinc fingerC2H2-type 16
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13660_68212856.0Zinc fingerC2H2-type 17
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13688_71012856.0Zinc fingerC2H2-type 18
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13716_73812856.0Zinc fingerC2H2-type 19
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13744_76612856.0Zinc fingerC2H2-type 20
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13772_79412856.0Zinc fingerC2H2-type 21
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13800_82212856.0Zinc fingerC2H2-type 22
HgeneZNF814chr19:58400135chr7:2416585ENST00000435989-13828_85012856.0Zinc fingerC2H2-type 23
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319185_268676810.0DomainRRM
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319185_268676791.0DomainRRM
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319285_324676810.0RepeatNote=WD 1
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319325_365676810.0RepeatNote=WD 2
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319366_425676810.0RepeatNote=WD 3
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319426_489676810.0RepeatNote=WD 4
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319490_553676810.0RepeatNote=WD 5
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319554_598676810.0RepeatNote=WD 6
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319599_642676810.0RepeatNote=WD 7
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003608761319643_685676810.0RepeatNote=WD 8
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319285_324676791.0RepeatNote=WD 1
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319325_365676791.0RepeatNote=WD 2
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319366_425676791.0RepeatNote=WD 3
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319426_489676791.0RepeatNote=WD 4
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319490_553676791.0RepeatNote=WD 5
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319554_598676791.0RepeatNote=WD 6
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319599_642676791.0RepeatNote=WD 7
TgeneEIF3Bchr19:58400135chr7:2416585ENST000003970111319643_685676791.0RepeatNote=WD 8


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Fusion Gene Sequence for ZNF814-EIF3B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>103004_103004_1_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000435989_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1242nt_BP=271nt
ATTTTGATTGGTGTTGGATTTATTTGTAGGAGAGGCTCCTGAGCGCTAGGTCCGCACTGTGGTGACTGAACCCAGAAGTCGGGGAGCAGT
TGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCA
TATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCA
GGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCC
CCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCG
TTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGA
GCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGA
GGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGGACTCCGCCTGC
TGTTCCCGCGCTGAGCTACAGGACTCCCGAGTGTGAGCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTC
CTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTT
TTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGC
CGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGC
AGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTA

>103004_103004_1_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000435989_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_2_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000435989_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=1169nt_BP=271nt
ATTTTGATTGGTGTTGGATTTATTTGTAGGAGAGGCTCCTGAGCGCTAGGTCCGCACTGTGGTGACTGAACCCAGAAGTCGGGGAGCAGT
TGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCA
TATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCA
GGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCC
CCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCG
TTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGA
GCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGA
GGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCCGTGTGTGCTGT
GGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGC
CATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTT
TTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCC
TGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCG

>103004_103004_2_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000435989_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_3_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000595295_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1026nt_BP=55nt
CTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGG
ACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAA
GCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGA
GAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTT
GCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCAT
TCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGGACTCCGCCTGCTGTTCCCGCGCTGAGCTACAGGACTCCCGAGTGTGA
GCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGT
GCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGA
TTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGC
GGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGG
GCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTTTTCTCCGCA

>103004_103004_3_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000595295_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=173AA_BP=
MHGGGTRHGGALPVGLRDTSSTARNGDASPSTEMLLGCVQAPWKHHWAQEKVPPVASLSLRSQRRRFQQKTPNKKEVEAGALNPPLQTPG

--------------------------------------------------------------
>103004_103004_4_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000595295_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=953nt_BP=55nt
CTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGG
ACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAA
GCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGA
GAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTT
GCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCAT
TCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTC
CCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGT
GTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTT
AGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTT
GCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGG

>103004_103004_4_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000595295_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=150AA_BP=10
MAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMM

--------------------------------------------------------------
>103004_103004_5_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000596604_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1125nt_BP=154nt
GGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTC
CCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGAC
TTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGA
ACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGA
ATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCG
CCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGA
AGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGGACTCCGCCTGCTGTTCCCGCGCTGAGCTACAGGACTCC
CGAGTGTGAGCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCT
CCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGC
AGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGAC
GCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCC
CCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTT

>103004_103004_5_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000596604_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=178AA_BP=38
MGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKK

--------------------------------------------------------------
>103004_103004_6_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000596604_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=1052nt_BP=154nt
GGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTC
CCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGAC
TTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGA
ACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGA
ATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCG
CCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGA
AGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCC
GCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCA
GCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTC
CGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTT
GAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGC

>103004_103004_6_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000596604_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=178AA_BP=38
MGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKK

--------------------------------------------------------------
>103004_103004_7_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597342_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1163nt_BP=192nt
CGGGGAGCAGTTGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGAC
CGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGG
CTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTG
CTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAA
CAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAA
ATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGAC
GACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGG
ACTCCGCCTGCTGTTCCCGCGCTGAGCTACAGGACTCCCGAGTGTGAGCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAG
CCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATT
GCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCT
GTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTA
CACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGC

>103004_103004_7_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597342_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_8_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597342_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=1090nt_BP=192nt
CGGGGAGCAGTTGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGAC
CGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGG
CTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTG
CTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAA
CAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAA
ATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGAC
GACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCC
GTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGC
CTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCT
TGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTT
TCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCA
CCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTTTTCTCCGCAGGTTGAACATGGAAATAAAAGCAAACTT

>103004_103004_8_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597342_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_9_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597807_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1174nt_BP=203nt
AACCCAGAAGTCGGGGAGCAGTTGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCC
AGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGG
CTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCT
TCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTA
AGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGA
AGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACA
GCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCAC
TGTGGGGACGGACTCCGCCTGCTGTTCCCGCGCTGAGCTACAGGACTCCCGAGTGTGAGCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGT
GTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGG
ATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTT
TGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCA
CGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGG
GAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTTTTCTCCGCAGGTTGAACATGGAAATAAAAGCAAACTTGTAT

>103004_103004_9_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597807_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_10_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597807_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=1101nt_BP=203nt
AACCCAGAAGTCGGGGAGCAGTTGTCCTCCGCTGCACAGAGGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCC
AGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGCCCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGG
CTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCT
TCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTA
AGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGA
AGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACA
GCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCAC
TGTGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGAC
TGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTC
CACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGC
CCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTC
CCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTTTTCTCCGCAGGTTGAACATGGAAATA

>103004_103004_10_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597807_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_11_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597832_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1224nt_BP=253nt
TTTATTTGTAGGAGAGGCTCCTGAGCGCTAGGTCCGCACTGTGGTGACTGAACCCAGAAGTCGGGGAGCAGTTGTCCTCCGCTGCACAGA
GGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGC
CCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTG
GCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCT
GAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGC
CTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAA
AAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTT
CGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGGACTCCGCCTGCTGTTCCCGCGCTGAGCTA
CAGGACTCCCGAGTGTGAGCCGCGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGA
CTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCT
GGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGA
CTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGA
CTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTG

>103004_103004_11_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597832_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_12_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597832_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=1151nt_BP=253nt
TTTATTTGTAGGAGAGGCTCCTGAGCGCTAGGTCCGCACTGTGGTGACTGAACCCAGAAGTCGGGGAGCAGTTGTCCTCCGCTGCACAGA
GGCTACTCTGGAGCTCTGTGACGGCGCCCAGCGTGACCCACTCCTGGGCCAGGATACGGACCGTCGTGCCCATATCTCCTGGCTGGTCGC
CCTATCCTCCCGACTCTGCTTAAAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTG
GCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCT
GAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGC
CTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAA
AAACGAGCGCCTGGAGTTGCGAGGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTT
CGTCACTGAAGAAATCATTCCCCTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTG
CAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTG
TGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGG
CGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGC
ATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCC

>103004_103004_12_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000597832_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=190AA_BP=50
MELCDGAQRDPLLGQDTDRRAHISWLVALSSRLCLKPRGSMAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQ
EQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGVDTDELDSNVDDWEEETIEFFVT

--------------------------------------------------------------
>103004_103004_13_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000600634_EIF3B_chr7_2416585_ENST00000360876_length(transcript)=1022nt_BP=51nt
AAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGC
CTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAA
ATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGA
AGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGA
GGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCC
CTCGGGAATCAGGAGTGACCTGGAGCACTGTGGGGACGGACTCCGCCTGCTGTTCCCGCGCTGAGCTACAGGACTCCCGAGTGTGAGCCG
CGGTTCCTCTGTTGCAGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGCCTCCTCCCTGTGCTC
TCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCTGCAGTGGGGGATTTA
AGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCGACGCCACTGGCGGCA
CCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCATCCCCATTGCGGGCAG
TGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGGTTTTCTCCGCAGGTT

>103004_103004_13_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000600634_EIF3B_chr7_2416585_ENST00000360876_length(amino acids)=173AA_BP=
MHGGGTRHGGALPVGLRDTSSTARNGDASPSTEMLLGCVQAPWKHHWAQEKVPPVASLSLRSQRRRFQQKTPNKKEVEAGALNPPLQTPG

--------------------------------------------------------------
>103004_103004_14_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000600634_EIF3B_chr7_2416585_ENST00000397011_length(transcript)=949nt_BP=51nt
AAACCACGTGGTTCGATGGCTGCCGCGGCTACGCTGAGGCTCTCCGCTCAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGC
CTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAA
ATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGA
AGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGA
GGAGGGGTGGACACTGACGAGCTGGACAGCAACGTGGACGACTGGGAAGAGGAGACCATTGAGTTCTTCGTCACTGAAGAAATCATTCCC
CTCGGGAATCAGGAGTGACCTGGAGCACTGTGCGCAGCCGTGTGTGCTGTGGAGCCGAGGCCGTCCTGCAGGAAGCCGCGTGACTCCCGC
CTCCTCCCTGTGCTCTCTGGCTCTGGACTGTGACTGCGCCTGGATTCTGCCATTGCGACACATTTTTGTGCCTTTCAGCCCCTGGTGTCT
GCAGTGGGGGATTTAAGGCACCCGCTTCCACTTCTTTCTTGTTTGGAGTTTTCTGTTGGAACCGCCGGCGTTGGCTCCGAAGACTTAGCG
ACGCCACTGGCGGCACCTTCTCCTGCGCCCAGTGATGTTTCCACGGTGCCTGTACACAGCCGAGCAGCATTTCCGTTGAAGGACTTGCAT
CCCCATTGCGGGCAGTGCTGGACGTGTCCCGGAGACCCACCGGGAGGGCGCCGCCATGCCTTGTACCCCCACCGTGCAGGTTGTGGCCGG

>103004_103004_14_ZNF814-EIF3B_ZNF814_chr19_58400135_ENST00000600634_EIF3B_chr7_2416585_ENST00000397011_length(amino acids)=150AA_BP=10
MAAAATLRLSAQVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMM

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Fusion Gene PPI Analysis for ZNF814-EIF3B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNF814-EIF3B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNF814-EIF3B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource