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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNRF2-BBS9 (FusionGDB2 ID:103152)

Fusion Gene Summary for ZNRF2-BBS9

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNRF2-BBS9
Fusion gene ID: 103152
HgeneTgene
Gene symbol

ZNRF2

BBS9

Gene ID

223082

27241

Gene namezinc and ring finger 2Bardet-Biedl syndrome 9
SynonymsRNF202B1|C18|D1|PTHB1
Cytomap

7p14.3

7p14.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase ZNRF2RING finger protein 202RING-type E3 ubiquitin transferase ZNRF2protein Ells2zinc and ring finger 2, E3 ubiquitin protein ligasezinc finger/RING finger 2zinc/RING finger protein 2protein PTHB1PTH-responsive osteosarcoma B1 proteinbardet-Biedl syndrome 9 proteinparathyroid hormone-responsive B1 gene protein
Modification date2020031320200320
UniProtAcc.

Q3SYG4

Ensembl transtripts involved in fusion geneENST00000323037, ENST00000459998, 
ENST00000425508, ENST00000482941, 
ENST00000242067, ENST00000350941, 
ENST00000354265, ENST00000355070, 
ENST00000396127, 
Fusion gene scores* DoF score7 X 5 X 5=17514 X 17 X 8=1904
# samples 819
** MAII scorelog2(8/175*10)=-1.12928301694497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1904*10)=-3.324962154977
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNRF2 [Title/Abstract] AND BBS9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNRF2(30395449)-BBS9(33303902), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ZNRF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BBS9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-B6-A409-01AZNRF2chr7

30363353

+BBS9chr7

33423278

+
ChimerDB4PRADTCGA-V1-A9ZK-01AZNRF2chr7

30395449

-BBS9chr7

33303902

+
ChimerDB4PRADTCGA-V1-A9ZKZNRF2chr7

30395449

+BBS9chr7

33303902

+


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Fusion Gene ORF analysis for ZNRF2-BBS9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000323037ENST00000425508ZNRF2chr7

30363353

+BBS9chr7

33423278

+
5CDS-intronENST00000323037ENST00000482941ZNRF2chr7

30363353

+BBS9chr7

33423278

+
5CDS-intronENST00000323037ENST00000482941ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000242067ZNRF2chr7

30363353

+BBS9chr7

33423278

+
In-frameENST00000323037ENST00000242067ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000350941ZNRF2chr7

30363353

+BBS9chr7

33423278

+
In-frameENST00000323037ENST00000350941ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000354265ZNRF2chr7

30363353

+BBS9chr7

33423278

+
In-frameENST00000323037ENST00000354265ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000355070ZNRF2chr7

30363353

+BBS9chr7

33423278

+
In-frameENST00000323037ENST00000355070ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000396127ZNRF2chr7

30363353

+BBS9chr7

33423278

+
In-frameENST00000323037ENST00000396127ZNRF2chr7

30395449

+BBS9chr7

33303902

+
In-frameENST00000323037ENST00000425508ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000242067ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-3CDSENST00000459998ENST00000242067ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000350941ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-3CDSENST00000459998ENST00000350941ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000354265ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-3CDSENST00000459998ENST00000354265ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000355070ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-3CDSENST00000459998ENST00000355070ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000396127ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-3CDSENST00000459998ENST00000396127ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-3CDSENST00000459998ENST00000425508ZNRF2chr7

30395449

+BBS9chr7

33303902

+
intron-intronENST00000459998ENST00000425508ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-intronENST00000459998ENST00000482941ZNRF2chr7

30363353

+BBS9chr7

33423278

+
intron-intronENST00000459998ENST00000482941ZNRF2chr7

30395449

+BBS9chr7

33303902

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000323037ZNRF2chr730363353+ENST00000242067BBS9chr733423278+333316169042490528
ENST00000323037ZNRF2chr730363353+ENST00000355070BBS9chr733423278+333316169042490528
ENST00000323037ZNRF2chr730363353+ENST00000350941BBS9chr733423278+333316169042490528
ENST00000323037ZNRF2chr730363353+ENST00000354265BBS9chr733423278+333316169042490528
ENST00000323037ZNRF2chr730363353+ENST00000396127BBS9chr733423278+333316169042490528
ENST00000323037ZNRF2chr730395449+ENST00000242067BBS9chr733303902+461117229043768954
ENST00000323037ZNRF2chr730395449+ENST00000355070BBS9chr733303902+459617229043753949
ENST00000323037ZNRF2chr730395449+ENST00000350941BBS9chr733303902+449117229043648914
ENST00000323037ZNRF2chr730395449+ENST00000354265BBS9chr733303902+450617229043663919
ENST00000323037ZNRF2chr730395449+ENST00000396127BBS9chr733303902+450617229043663919
ENST00000323037ZNRF2chr730395449+ENST00000425508BBS9chr733303902+217317229042172423

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000323037ENST00000242067ZNRF2chr730363353+BBS9chr733423278+0.0173274840.9826726
ENST00000323037ENST00000355070ZNRF2chr730363353+BBS9chr733423278+0.0173274840.9826726
ENST00000323037ENST00000350941ZNRF2chr730363353+BBS9chr733423278+0.0173274840.9826726
ENST00000323037ENST00000354265ZNRF2chr730363353+BBS9chr733423278+0.0173274840.9826726
ENST00000323037ENST00000396127ZNRF2chr730363353+BBS9chr733423278+0.0173274840.9826726
ENST00000323037ENST00000242067ZNRF2chr730395449+BBS9chr733303902+0.001322650.9986773
ENST00000323037ENST00000355070ZNRF2chr730395449+BBS9chr733303902+0.0012071220.9987929
ENST00000323037ENST00000350941ZNRF2chr730395449+BBS9chr733303902+0.001414070.99858594
ENST00000323037ENST00000354265ZNRF2chr730395449+BBS9chr733303902+0.001293260.9987067
ENST00000323037ENST00000396127ZNRF2chr730395449+BBS9chr733303902+0.0013529380.99864703
ENST00000323037ENST00000425508ZNRF2chr730395449+BBS9chr733303902+0.03220830.9677917

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Fusion Genomic Features for ZNRF2-BBS9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ZNRF2chr730363353+BBS9chr733423277+4.79E-050.9999521
ZNRF2chr730395449+BBS9chr733303901+2.95E-060.999997
ZNRF2chr730363353+BBS9chr733423277+4.79E-050.9999521
ZNRF2chr730395449+BBS9chr733303901+2.95E-060.999997

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ZNRF2-BBS9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:30395449/chr7:33303902)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BBS9

Q3SYG4

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization. {ECO:0000269|PubMed:17574030, ECO:0000269|PubMed:22072986}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNRF2chr7:30363353chr7:33423278ENST00000323037+25124_127188289.0Compositional biasNote=Poly-Gly
HgeneZNRF2chr7:30363353chr7:33423278ENST00000323037+2536_40188289.0Compositional biasNote=Poly-Gly
HgeneZNRF2chr7:30363353chr7:33423278ENST00000323037+2541_97188289.0Compositional biasNote=Ala-rich
HgeneZNRF2chr7:30395449chr7:33303902ENST00000323037+35124_127223289.0Compositional biasNote=Poly-Gly
HgeneZNRF2chr7:30395449chr7:33303902ENST00000323037+3536_40223289.0Compositional biasNote=Poly-Gly
HgeneZNRF2chr7:30395449chr7:33303902ENST00000323037+3541_97223289.0Compositional biasNote=Ala-rich
TgeneBBS9chr7:30363353chr7:33423278ENST000004255080101_4070311.0RegionSeven-bladed beta-propeller

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNRF2chr7:30363353chr7:33423278ENST00000323037+25199_240188289.0Zinc fingerRING-type%3B atypical
HgeneZNRF2chr7:30395449chr7:33303902ENST00000323037+35199_240223289.0Zinc fingerRING-type%3B atypical
TgeneBBS9chr7:30363353chr7:33423278ENST0000024206716231_407596888.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30363353chr7:33423278ENST0000035094114211_407556848.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30363353chr7:33423278ENST0000039612715221_407561853.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30395449chr7:33303902ENST000002420675231_407205888.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30395449chr7:33303902ENST000003509415211_407205848.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30395449chr7:33303902ENST000003961275221_407205853.0RegionSeven-bladed beta-propeller
TgeneBBS9chr7:30395449chr7:33303902ENST000004255085101_407160311.0RegionSeven-bladed beta-propeller


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Fusion Gene Sequence for ZNRF2-BBS9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>103152_103152_1_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000242067_length(transcript)=3333nt_BP=1616nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAACG
ATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGG
AGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAA
TGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAAC
TCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGG
CAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCA
GGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCA
CCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACT
GAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGT
CATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAG
ACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAA
CATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTG
GAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTT
GTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATT
TTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGC
ATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAA
AGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTG
TTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATC
CCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTT
ATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTGCCA

>103152_103152_1_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000242067_length(amino acids)=528AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNERYRIQSEQFEDLWLITNELILRLQEYFEKQGV
KDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGN
LFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLK

--------------------------------------------------------------
>103152_103152_2_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000350941_length(transcript)=3333nt_BP=1616nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAACG
ATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGG
AGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAA
TGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAAC
TCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGG
CAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCA
GGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCA
CCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACT
GAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGT
CATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAG
ACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAA
CATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTG
GAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTT
GTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATT
TTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGC
ATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAA
AGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTG
TTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATC
CCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTT
ATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTGCCA

>103152_103152_2_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000350941_length(amino acids)=528AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNERYRIQSEQFEDLWLITNELILRLQEYFEKQGV
KDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGN
LFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLK

--------------------------------------------------------------
>103152_103152_3_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000354265_length(transcript)=3333nt_BP=1616nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAACG
ATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGG
AGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAA
TGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAAC
TCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGG
CAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCA
GGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCA
CCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACT
GAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGT
CATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAG
ACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAA
CATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTG
GAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTT
GTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATT
TTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGC
ATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAA
AGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTG
TTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATC
CCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTT
ATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTGCCA

>103152_103152_3_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000354265_length(amino acids)=528AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNERYRIQSEQFEDLWLITNELILRLQEYFEKQGV
KDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGN
LFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLK

--------------------------------------------------------------
>103152_103152_4_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000355070_length(transcript)=3333nt_BP=1616nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAACG
ATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGG
AGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAA
TGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAAC
TCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGG
CAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCA
GGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCA
CCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACT
GAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGT
CATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAG
ACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAA
CATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTG
GAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTT
GTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATT
TTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGC
ATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAA
AGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTG
TTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATC
CCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTT
ATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTGCCA

>103152_103152_4_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000355070_length(amino acids)=528AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNERYRIQSEQFEDLWLITNELILRLQEYFEKQGV
KDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGN
LFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLK

--------------------------------------------------------------
>103152_103152_5_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000396127_length(transcript)=3333nt_BP=1616nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAACG
ATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGG
AGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAA
TGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAAC
TCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGG
CAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCA
GGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCA
CCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACT
GAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGT
CATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAG
ACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAA
CATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTG
GAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTT
GTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATT
TTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGC
ATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAA
AGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTG
TTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATC
CCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTT
ATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTGCCA

>103152_103152_5_ZNRF2-BBS9_ZNRF2_chr7_30363353_ENST00000323037_BBS9_chr7_33423278_ENST00000396127_length(amino acids)=528AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNERYRIQSEQFEDLWLITNELILRLQEYFEKQGV
KDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGN
LFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLK

--------------------------------------------------------------
>103152_103152_6_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000242067_length(transcript)=4611nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCATGATTTAAAGGGAGTGATAGTCACTCTGAGTGATGATGG
TCACTTGCAGTGTTCATACCTGGGGACAGATCCTTCTCTGTTCCAAGCTCCAAACGTTCAATCTCGAGAACTAAACTATGATGAACTTGA
TGTAGAAATGAAAGAACTTCAGAAAATCATCAAAGATGTTAACAAATCACAAGGTGTTTGGCCCATGACTGAGAGAGAAGATGACTTGAA
CGTTTCTGTCGTGGTTTCTCCTAACTTTGATTCAGTTTCTCAAGCGACCGATGTTGAGGTGGGAACTGACCTTGTCCCTTCTGTCACGGT
GAAGGTCACACTGCAGAACAGAGTGATATTGCAAAAAGCCAAATTATCAGTCTACGTGCAACCACCATTAGAATTGACTTGTGATCAGTT
CACCTTTGAATTTATGACACCAGATTTGACTAGAACAGTAAGCTTTTCTGTTTATCTGAAAAGAAGTTATACACCATCAGAATTGGAAGG
AAATGCTGTTGTTTCTTATTCCAGACCAACAGATCGAAATCCTGATGGCATTCCGCGAGTTATCCAATGTAAATTTAGACTTCCCCTAAA
GTTAATTTGCCTACCAGGTCAGCCTTCAAAAACTGCAAGCCACAAAATTACTATTGATACCAACAAATCTCCAGTCAGTCTTCTTAGTCT
CTTCCCAGGTTTTGCCAGTCAGTCAGATGATGATCAGGTGAATGTAATGGGTTTTCACTTCTTAGGAGGTGCTCGAATTACTGTTCTTGC
TTCCAAAACTTCTCAACGATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGA
ATATTTTGAAAAACAGGGAGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCA
TTTTGAGCTACGGATAAATGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGC
AAGATTCAAAGATAAAACTCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGC
AGTGGAGGAAAACCAAGGCAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCA
GAAGCTTAGTGCTGACCAGGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGT
GGATGCCGCCATTTCCCACCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACC
CAAAGACACAAGCCAACTGAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGC
AGCCCCACAGACCATGGTCATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGA
ACTGTTTACCAACCACAGACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAG
TTGTTTGGTTGAGAGGAACATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTC
CTAAAGCTCACCTTCCTGGAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAG
TCAGCTGAAACTTGTCTTGTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGAC
ATAGTTTTGGGTTAGATTTTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATG
TATCAAGTTTAATAAAGCATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTAT
TTCTTCAAAGGAAAGGAAAGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATG
AAACTTTCATGTGATTTGTTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGA
AGCTAGTACATTAACATCCCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAG
TTAAAATTTAAGGTTTTTATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAAT

>103152_103152_6_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000242067_length(amino acids)=954AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY
CSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDV
EMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFT
FEFMTPDLTRTVSFSVYLKRSYTPSELEGNAVVSYSRPTDRNPDGIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVSLLSLF
PGFASQSDDDQVNVMGFHFLGGARITVLASKTSQRYRIQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHF
ELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQK
LSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAA

--------------------------------------------------------------
>103152_103152_7_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000350941_length(transcript)=4491nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCATGATTTAAAGGGAGTGATAGTCACTCTGAGTGATGATGG
TCACTTGCAGTGTTCATACCTGGGGACAGATCCTTCTCTGTTCCAAGCTCCAAACGTTCAATCTCGAGAACTAAACTATGATGAACTTGA
TGTAGAAATGAAAGAACTTCAGAAAATCATCAAAGATGTTAACAAATCACAAGGTGTTTGGCCCATGACTGAGAGAGAAGATGACTTGAA
CGTTTCTGTCGTGGTTTCTCCTAACTTTGATTCAGTTTCTCAAGCGACCGATGTTGAGGTGGGAACTGACCTTGTCCCTTCTGTCACGGT
GAAGGTCACACTGCAGAACAGAGTGATATTGCAAAAAGCCAAATTATCAGTCTACGTGCAACCACCATTAGAATTGACTTGTGATCAGTT
CACCTTTGAATTTATGAGCATTCCGCGAGTTATCCAATGTAAATTTAGACTTCCCCTAAAGTTAATTTGCCTACCAGGTCAGCCTTCAAA
AACTGCAAGCCACAAAATTACTATTGATACCAACAAATCTCCAGTCAGTCTTCTTAGTCTCTTCCCAGGTTTTGCCAGTCAGTCAGATGA
TGATCAGGTGAATGTAATGGGTTTTCACTTCTTAGGAGGTGCTCGAATTACTGTTCTTGCTTCCAAAACTTCTCAACGATATCGCATTCA
GAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACAGGGAGTCAAAGATTT
TGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGATAAATGGTGAAAAATT
AGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAAAACTCCTGCCCCTCT
TCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCAAGGCAATCTGTTCCA
GTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGACCAGGTTGCTATTCT
GGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTCCCACCTGTTGAAGAC
TTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCAACTGAAGAAACATAT
CACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCATGGTCATGCCAGGTGG
TTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCACAGACATCTCACTGC
AGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAGGAACATCCCCATCTC
AAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTCCTGGAGATGACATGC
ATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGTCTTGTTTTGCCAGGA
AAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAGATTTTATAATGCAAA
GATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAAAGCATCTCATTGTCA
AATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAGGAAAGGAATTGAAGA
CTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGATTTGTTCTATTAAGCT
AAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAACATCCCCTTTTCATTA
CCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTTTTTATGTGTAAGAAG

>103152_103152_7_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000350941_length(amino acids)=914AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY
CSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDV
EMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFT
FEFMSIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVSLLSLFPGFASQSDDDQVNVMGFHFLGGARITVLASKTSQRYRIQS
EQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQ
HLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLLKTC
LSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMVMPGGCTTIPESDLEERSVEQDSTELFTNHRHLTAE

--------------------------------------------------------------
>103152_103152_8_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000354265_length(transcript)=4506nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCATGATTTAAAGGGAGTGATAGTCACTCTGAGTGATGATGG
TCACTTGCAGTGTTCATACCTGGGGACAGATCCTTCTCTGTTCCAAGCTCCAAACGTTCAATCTCGAGAACTAAACTATGATGAACTTGA
TGTAGAAATGAAAGAACTTCAGAAAATCATCAAAGATGTTAACAAATCACAAGGTGTTTGGCCCATGACTGAGAGAGAAGATGACTTGAA
CGTTTCTGTCGTGGTTTCTCCTAACTTTGATTCAGTTTCTCAAGCGACCGATGTTGAGGTGGGAACTGACCTTGTCCCTTCTGTCACGGT
GAAGGTCACACTGCAGAACAGAGTGATATTGCAAAAAGCCAAATTATCAGTCTACGTGCAACCACCATTAGAATTGACTTGTGATCAGTT
CACCTTTGAATTTATGAGTCTGAATGTTTTAGGCATTCCGCGAGTTATCCAATGTAAATTTAGACTTCCCCTAAAGTTAATTTGCCTACC
AGGTCAGCCTTCAAAAACTGCAAGCCACAAAATTACTATTGATACCAACAAATCTCCAGTCAGTCTTCTTAGTCTCTTCCCAGGTTTTGC
CAGTCAGTCAGATGATGATCAGGTGAATGTAATGGGTTTTCACTTCTTAGGAGGTGCTCGAATTACTGTTCTTGCTTCCAAAACTTCTCA
ACGATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACA
GGGAGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGAT
AAATGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAA
AACTCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCA
AGGCAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGA
CCAGGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTC
CCACCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCA
ACTGAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCAT
GGTCATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCA
CAGACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAG
GAACATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTC
CTGGAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGT
CTTGTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAG
ATTTTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAA
AGCATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAG
GAAAGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGAT
TTGTTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAAC
ATCCCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTT
TTTATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTG

>103152_103152_8_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000354265_length(amino acids)=919AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY
CSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDV
EMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFT
FEFMSLNVLGIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVSLLSLFPGFASQSDDDQVNVMGFHFLGGARITVLASKTSQR
YRIQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKT
PAPLQHLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISH
LLKTCLSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMVMPGGCTTIPESDLEERSVEQDSTELFTNHR

--------------------------------------------------------------
>103152_103152_9_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000355070_length(transcript)=4596nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCATGATTTAAAGGGAGTGATAGTCACTCTGAGTGATGATGG
TCACTTGCAGTGTTCATACCTGGGGACAGATCCTTCTCTGTTCCAAGCTCCAAACGTTCAATCTCGAGAACTAAACTATGATGAACTTGA
TGTAGAAATGAAAGAACTTCAGAAAATCATCAAAGATGTTAACAAATCACAAGGTGTTTGGCCCATGACTGAGAGAGAAGATGACTTGAA
CGTTTCTGTCGTGGTTTCTCCTAACTTTGATTCAGTTTCTCAAGCGACCGATGTTGAGGTGGGAACTGACCTTGTCCCTTCTGTCACGGT
GAAGGTCACACTGCAGAACAGAGTGATATTGCAAAAAGCCAAATTATCAGTCTACGTGCAACCACCATTAGAATTGACTTGTGATCAGTT
CACCTTTGAATTTATGACACCAGATTTGACTAGAACAGTAAGCTTTTCTGTTTATCTGAAAAGAAGTTATACACCATCAGAATTGGAAGG
AAATGCTGTTGTTTCTTATTCCAGACCAACAGGCATTCCGCGAGTTATCCAATGTAAATTTAGACTTCCCCTAAAGTTAATTTGCCTACC
AGGTCAGCCTTCAAAAACTGCAAGCCACAAAATTACTATTGATACCAACAAATCTCCAGTCAGTCTTCTTAGTCTCTTCCCAGGTTTTGC
CAGTCAGTCAGATGATGATCAGGTGAATGTAATGGGTTTTCACTTCTTAGGAGGTGCTCGAATTACTGTTCTTGCTTCCAAAACTTCTCA
ACGATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACA
GGGAGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGAT
AAATGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAA
AACTCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCA
AGGCAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGA
CCAGGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTC
CCACCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCA
ACTGAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCAT
GGTCATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCA
CAGACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAG
GAACATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTC
CTGGAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGT
CTTGTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAG
ATTTTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAA
AGCATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAG
GAAAGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGAT
TTGTTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAAC
ATCCCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTT
TTTATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTG

>103152_103152_9_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000355070_length(amino acids)=949AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY
CSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDV
EMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFT
FEFMTPDLTRTVSFSVYLKRSYTPSELEGNAVVSYSRPTGIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVSLLSLFPGFAS
QSDDDQVNVMGFHFLGGARITVLASKTSQRYRIQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHFELRIN
GEKLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQKLSADQ
VAILEAAFLPLQEDTQELGWEETVDAAISHLLKTCLSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMV

--------------------------------------------------------------
>103152_103152_10_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000396127_length(transcript)=4506nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCATGATTTAAAGGGAGTGATAGTCACTCTGAGTGATGATGG
TCACTTGCAGTGTTCATACCTGGGGACAGATCCTTCTCTGTTCCAAGCTCCAAACGTTCAATCTCGAGAACTAAACTATGATGAACTTGA
TGTAGAAATGAAAGAACTTCAGAAAATCATCAAAGATGTTAACAAATCACAAGGTGTTTGGCCCATGACTGAGAGAGAAGATGACTTGAA
CGTTTCTGTCGTGGTTTCTCCTAACTTTGATTCAGTTTCTCAAGCGACCGATGTTGAGGTGGGAACTGACCTTGTCCCTTCTGTCACGGT
GAAGGTCACACTGCAGAACAGAGTGATATTGCAAAAAGCCAAATTATCAGTCTACGTGCAACCACCATTAGAATTGACTTGTGATCAGTT
CACCTTTGAATTTATGAATCGAAATCCTGATGGCATTCCGCGAGTTATCCAATGTAAATTTAGACTTCCCCTAAAGTTAATTTGCCTACC
AGGTCAGCCTTCAAAAACTGCAAGCCACAAAATTACTATTGATACCAACAAATCTCCAGTCAGTCTTCTTAGTCTCTTCCCAGGTTTTGC
CAGTCAGTCAGATGATGATCAGGTGAATGTAATGGGTTTTCACTTCTTAGGAGGTGCTCGAATTACTGTTCTTGCTTCCAAAACTTCTCA
ACGATATCGCATTCAGAGTGAACAATTTGAAGATCTTTGGCTCATAACCAATGAGCTTATTCTTCGCCTTCAAGAATATTTTGAAAAACA
GGGAGTCAAAGATTTTGCATGTTCTTTTTCGGGATCTATACCCCTTCAAGAATATTTTGAGTTGATTGATCATCATTTTGAGCTACGGAT
AAATGGTGAAAAATTAGAAGAACTCTTATCTGAGAGAGCTGTACAATTTCGGGCCATTCAACGCCGGCTACTAGCAAGATTCAAAGATAA
AACTCCTGCCCCTCTTCAACACCTGGACACCTTGTTAGATGGAACCTACAAGCAGGTAATTGCTCTAGCAGATGCAGTGGAGGAAAACCA
AGGCAATCTGTTCCAGTCATTCACCAGGCTGAAGAGTGCCACCCATTTGGTGATTCTGCTGATCGCGCTGTGGCAGAAGCTTAGTGCTGA
CCAGGTTGCTATTCTGGAAGCGGCATTTCTGCCGCTACAAGAAGACACTCAAGAATTGGGCTGGGAAGAAACGGTGGATGCCGCCATTTC
CCACCTGTTGAAGACTTGCCTGTCGAAGAGTTCTAAGGAGCAGGCTTTGAACCTCAACAGCCAGCTGAACATACCCAAAGACACAAGCCA
ACTGAAGAAACATATCACCTTGCTCTGCGATAGATTATCCAAAGGTGGCCGTCTCTGCCTAAGTACCGATGCAGCAGCCCCACAGACCAT
GGTCATGCCAGGTGGTTGTACTACAATCCCAGAGTCAGACCTAGAAGAAAGATCAGTAGAACAAGACTCTACAGAACTGTTTACCAACCA
CAGACATCTCACTGCAGAGACACCCAGGCCTGAAGTTTCACCCCTCCAAGGAGTCTCGGAATAATTCAAGTAGAGTTGTTTGGTTGAGAG
GAACATCCCCATCTCAAGGCCGAACCTGTGTGAACCTCATGCCAAGCACAGATATAGGGCTGGCGCAGGTGCTTCCTAAAGCTCACCTTC
CTGGAGATGACATGCATAGAAAGAGGGGTTGGGACTTTTTACTTCACTAGGAGAACTTGTAACACCATGGGGAAGTCAGCTGAAACTTGT
CTTGTTTTGCCAGGAAAGGAAGTAGTTGCCTTTGGTCATCCATCTGCTAATAGTCACAGAATACAGTGAAATGACATAGTTTTGGGTTAG
ATTTTATAATGCAAAGATTCAGATCCAAAATAATTTCATACCCCATTTTTTCACAGAATTCTTATATAGTAAATGTATCAAGTTTAATAA
AGCATCTCATTGTCAAATAATATCTTGGATTTTATTTATAATTAGAGGGATTTATGAGTGATTGCTCTACATTATTTCTTCAAAGGAAAG
GAAAGGAATTGAAGACTTTGCTACTCTCTGGTAAGACTTGAATGTGATTATTTTATAAATAAAAGAACCACTATGAAACTTTCATGTGAT
TTGTTCTATTAAGCTAAACGTGGAAGAAGGGAAGTTTTCTAGTATTGTATGAAAATGTTTAAATATTTTCAAGGAAGCTAGTACATTAAC
ATCCCCTTTTCATTACCCCATTGGGTGGCACCTTTTAAAAATCCAGGTTATTAAAGGATTCACACTTTATTACAGTTAAAATTTAAGGTT
TTTATGTGTAAGAAGTGAAAGAAACTTTGCTAATTTCAAGTTCGAATTACAGTTGTGAGATTGATTTATTTAAATAAAAATATGCCTTTG

>103152_103152_10_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000396127_length(amino acids)=919AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY
CSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLGTDPSLFQAPNVQSRELNYDELDV
EMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPNFDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFT
FEFMNRNPDGIPRVIQCKFRLPLKLICLPGQPSKTASHKITIDTNKSPVSLLSLFPGFASQSDDDQVNVMGFHFLGGARITVLASKTSQR
YRIQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHFELRINGEKLEELLSERAVQFRAIQRRLLARFKDKT
PAPLQHLDTLLDGTYKQVIALADAVEENQGNLFQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISH
LLKTCLSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMVMPGGCTTIPESDLEERSVEQDSTELFTNHR

--------------------------------------------------------------
>103152_103152_11_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000425508_length(transcript)=2173nt_BP=1722nt
GCGGGCCACGTGCGGGAGGAGGGGCCGCCTTCTGGTTGGCGCCCGGTGTCCGTTCCTCCTATCGGCGTAGGCCCCGCGAGGAAGACAAGG
GCGCGCCCTGGCTGGGAGGGCGTGGCCAGAGACCTGTCCATCACCGAGTCCACGAGTGGCAGCACCTACCACACCGCAGTACCTTGGCGA
GGCGGAGCAGGGGCAGGCAGGTCGCGGAAGGGGGAGGCGGAGCAAGGCCGGCGGGAGCCAATCGGCCTGGCGGCACGAGGGGGCGGGGGC
GGGGTCAACGCGCGCGACCCAAACACACGGGCCGGGCGCACCCTGCAGCCGCGCCGCTCCGCGGCCTTCCGGCGCGGGGCCGGGGAACCT
CCTCCCCATCTGCGCACCCCCCGCCTTCGCGGCCCAGATCCTCCCGCCAGCCCGGCCCCTCCTTCGCAGGGGGAGCGAGGCGACGGTTGC
CGGGAAGCGCGCGCCACCTCTCCCTCCCATTTTTCGTTCTCCCCTCGCGCGCCACCCGTTTTTCCTCTTTCTCCGTTAATAACAGCTGGG
TGGCTGGGGGAGGAGGGAAGGTGGCCCCGGCGGAGTCTGGGCGGGCGCCTCCCACTCAGCCGCCAGCCGCCGTGGGAGCCGGAGGATGGC
GGCGGTAGCAGCGGCCGCCCGAGAGGAGGCGGTGCCGAGATCGGGGGCGCCGAGCGCGGCAGCAGAGAGCGGTAGCGGCCCGTCGTGGCG
CACCAGAACCGAAACCAGCGGCAGCCGCACGGCCACTTGAGCCGCCCCTTCCTGCTGGAGCCAGCGAGGGGTGCCTGCAGCCGGGACCCC
TTCCTCTCCGCGTCTCCTCGTCTCCCGCGCCCGCGTCAGGCCGTCGGCCTCGCCCGCCGCCCCAAGAAGAGCGCGCCGGGCGCCGACTGC
CCCTCTGGACGCCGGGCGGCGGCCCTGGACGTGCGGGGGCCTCTCTGGGCCGGCCGCGGCGCCTGGGCCCTGCCCTCTAGCTCCCGCGCT
CGCTCCCGCCCTCCCGGCTCTCGGGGCGCAGCGCGCGGGCCCGGCCCGGGGCAGGGCGGACATGGGCGCCAAACAGAGCGGCCCGGCCGC
CGCTAACGGCCGCACGCGCGCGTACTCGGGCTCGGATCTACCTTCCAGTAGCAGCGGAGGCGCCAATGGGACCGCGGGCGGCGGCGGGGG
CGCTCGGGCCGCCGCCGCGGGGAGGTTCCCGGCTCAGGTGCCCAGCGCGCACCAGCCCAGCGCCTCCGGCGGCGCCGCGGCGGCCGCGGC
GGCCCCGGCAGCCCCGGCGGCCCCGCGCAGCCGCTCCCTCGGCGGGGCCGTGGGGAGCGTGGCGTCGGGGGCCCGCGCGGCGCAGTCCCC
CTTCAGCATCCCGAACAGCAGCAGCGGCCCGTACGGCTCGCAGGACTCGGTGCACAGCAGCCCTGAGGACGGCGGCGGCGGCCGGGACCG
GCCGGTGGGCGGGAGCCCCGGCGGGCCGCGCCTGGTGATCGGCTCCTTACCAGCTCACCTCTCGCCGCACATGTTTGGAGGATTTAAGTG
CCCTGTATGCTCAAAATTTGTATCCTCAGATGAAATGGATTTGCATCTTGTAATGTGTTTAACAAAGCCACGAATAACCTATAATGAGGA
TGTACTGAGTAAAGATGCTGGGGAATGTGCAATATGCCTTGAAGAATTGCAGCAGGGAGATACTATAGCACGACTGCCTTGTCTATGCAT
ATATCATAAAGGGTACCAGGTACTTGCTTTTGCAACAGATGCAGATAAAAGGCAGGAGACTGAACAGCAAAAACTTGGTTCTGGAAAAAG
ACTAGTTGTGGATTGGACTCTAAATATTGGAGAGCAAGCCCTTGACATATGTATTGTCTCTTTCAATCAGTCGGCATCCTCTGTTTTTGT
TCTTGGTGAGAGAAACTTTTTTTGCCTTAAGGATAATGGACAAATTCGATTCATGAAGAAGCTTGATTGGAGCCCAAGTTGTTTTCTGCC
ATATTGCTCAGTTTCTGAAGGAACAATAAATACTTTGATTGGAAATCATAATAACATGCTGCATATTTATCAAGATGTGACACTGAAGTG
GGCCACCCAACTTCCCCACATTCCTGTAGCAGTAAGAGTGGGCTGTTTGCAATTTTCTTTATGGAAGCATTTGTTGCCTCGATCTTCCAC

>103152_103152_11_ZNRF2-BBS9_ZNRF2_chr7_30395449_ENST00000323037_BBS9_chr7_33303902_ENST00000425508_length(amino acids)=423AA_BP=2
MDAGRRPWTCGGLSGPAAAPGPCPLAPALAPALPALGAQRAGPARGRADMGAKQSGPAAANGRTRAYSGSDLPSSSSGGANGTAGGGGGA
RAAAAGRFPAQVPSAHQPSASGGAAAAAAAPAAPAAPRSRSLGGAVGSVASGARAAQSPFSIPNSSSGPYGSQDSVHSSPEDGGGGRDRP
VGGSPGGPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDVLSKDAGECAICLEELQQGDTIARLPCLCIY
HKGYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLNIGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNRF2-BBS9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneBBS9chr7:30363353chr7:33423278ENST000002420671623685_765596.3333333333334888.0LZTL1
TgeneBBS9chr7:30363353chr7:33423278ENST000003509411421685_765556.3333333333334848.0LZTL1
TgeneBBS9chr7:30363353chr7:33423278ENST000003961271522685_765561.3333333333334853.0LZTL1
TgeneBBS9chr7:30363353chr7:33423278ENST00000425508010685_7650311.0LZTL1
TgeneBBS9chr7:30395449chr7:33303902ENST00000242067523685_765205.66666666666666888.0LZTL1
TgeneBBS9chr7:30395449chr7:33303902ENST00000350941521685_765205.66666666666666848.0LZTL1
TgeneBBS9chr7:30395449chr7:33303902ENST00000396127522685_765205.66666666666666853.0LZTL1
TgeneBBS9chr7:30395449chr7:33303902ENST00000425508510685_765160.66666666666666311.0LZTL1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNRF2-BBS9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNRF2-BBS9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource