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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ZNRF3-ASCC2 (FusionGDB2 ID:103161)

Fusion Gene Summary for ZNRF3-ASCC2

check button Fusion gene summary
Fusion gene informationFusion gene name: ZNRF3-ASCC2
Fusion gene ID: 103161
HgeneTgene
Gene symbol

ZNRF3

ASCC2

Gene ID

84133

84164

Gene namezinc and ring finger 3activating signal cointegrator 1 complex subunit 2
SynonymsBK747E2.3|RNF203ASC1p100|p100
Cytomap

22q12.1

22q12.2

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase ZNRF3CTA-292E10.6RING finger protein 203RING-type E3 ubiquitin transferase ZNRF3novel C3HC4 type Zinc finger (ring finger)zinc/RING finger protein 3activating signal cointegrator 1 complex subunit 2ASC-1 complex subunit P100trip4 complex subunit p100
Modification date2020031320200313
UniProtAcc.

Q9H1I8

Ensembl transtripts involved in fusion geneENST00000544604, ENST00000332811, 
ENST00000402174, ENST00000406323, 
ENST00000478812, ENST00000542393, 
ENST00000307790, ENST00000397771, 
Fusion gene scores* DoF score26 X 11 X 18=514814 X 17 X 6=1428
# samples 3917
** MAII scorelog2(39/5148*10)=-3.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1428*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ZNRF3 [Title/Abstract] AND ASCC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointZNRF3(29280054)-ASCC2(30221246), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneZNRF3

GO:0016567

protein ubiquitination

22575959

TgeneASCC2

GO:0006355

regulation of transcription, DNA-templated

12077347


check buttonFusion gene breakpoints across ZNRF3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASCC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A094-01AZNRF3chr22

29280053

+ASCC2chr22

30221245

-
ChimerDB4BRCATCGA-A8-A094-01AZNRF3chr22

29280053

+ASCC2chr22

30221768

-
ChimerDB4BRCATCGA-A8-A094-01AZNRF3chr22

29280054

-ASCC2chr22

30221246

-
ChimerDB4BRCATCGA-A8-A094-01AZNRF3chr22

29280054

+ASCC2chr22

30221246

-
ChimerDB4BRCATCGA-A8-A094-01AZNRF3chr22

29280054

+ASCC2chr22

30221769

-
ChimerDB4BRCATCGA-A8-A094ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
ChimerDB4BRCATCGA-A8-A094ZNRF3chr22

29280054

+ASCC2chr22

30221769

-


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Fusion Gene ORF analysis for ZNRF3-ASCC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000544604ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
5CDS-intronENST00000544604ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5CDS-intronENST00000544604ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
5CDS-intronENST00000544604ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
5CDS-intronENST00000544604ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5CDS-intronENST00000544604ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
5UTR-3CDSENST00000332811ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
5UTR-3CDSENST00000332811ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5UTR-3CDSENST00000332811ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
5UTR-3CDSENST00000332811ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
5UTR-3CDSENST00000332811ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
5UTR-3CDSENST00000332811ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5UTR-3CDSENST00000332811ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
5UTR-3CDSENST00000332811ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
5UTR-3CDSENST00000332811ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
5UTR-3CDSENST00000332811ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
5UTR-intronENST00000332811ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
5UTR-intronENST00000332811ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5UTR-intronENST00000332811ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
5UTR-intronENST00000332811ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
5UTR-intronENST00000332811ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
5UTR-intronENST00000332811ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
In-frameENST00000544604ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
In-frameENST00000544604ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
In-frameENST00000544604ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
In-frameENST00000544604ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
In-frameENST00000544604ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
In-frameENST00000544604ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
In-frameENST00000544604ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
In-frameENST00000544604ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
In-frameENST00000544604ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
In-frameENST00000544604ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000402174ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000402174ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-3CDSENST00000402174ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000402174ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-3CDSENST00000402174ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000402174ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-3CDSENST00000402174ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000402174ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-3CDSENST00000402174ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000402174ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000406323ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000406323ENST00000307790ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-3CDSENST00000406323ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000406323ENST00000307790ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-3CDSENST00000406323ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000406323ENST00000397771ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-3CDSENST00000406323ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-3CDSENST00000406323ENST00000397771ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-3CDSENST00000406323ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-3CDSENST00000406323ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-intronENST00000402174ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-intronENST00000402174ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-intronENST00000402174ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-intronENST00000402174ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-intronENST00000402174ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-intronENST00000402174ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-intronENST00000406323ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221245

-
intron-intronENST00000406323ENST00000478812ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-intronENST00000406323ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221246

-
intron-intronENST00000406323ENST00000478812ZNRF3chr22

29280054

+ASCC2chr22

30221769

-
intron-intronENST00000406323ENST00000542393ZNRF3chr22

29280053

+ASCC2chr22

30221768

-
intron-intronENST00000406323ENST00000542393ZNRF3chr22

29280054

+ASCC2chr22

30221769

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000544604ZNRF3chr2229280054+ENST00000307790ASCC2chr2230221246-29144751752508777
ENST00000544604ZNRF3chr2229280054+ENST00000397771ASCC2chr2230221246-28804751752508777
ENST00000544604ZNRF3chr2229280054+ENST00000542393ASCC2chr2230221246-25714751752439754
ENST00000544604ZNRF3chr2229280054+ENST00000307790ASCC2chr2230221769-30734751752667830
ENST00000544604ZNRF3chr2229280054+ENST00000397771ASCC2chr2230221769-30394751752667830
ENST00000544604ZNRF3chr2229280053+ENST00000307790ASCC2chr2230221245-29144751752508777
ENST00000544604ZNRF3chr2229280053+ENST00000397771ASCC2chr2230221245-28804751752508777
ENST00000544604ZNRF3chr2229280053+ENST00000542393ASCC2chr2230221245-25714751752439754
ENST00000544604ZNRF3chr2229280053+ENST00000307790ASCC2chr2230221768-30734751752667830
ENST00000544604ZNRF3chr2229280053+ENST00000397771ASCC2chr2230221768-30394751752667830

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000544604ENST00000307790ZNRF3chr2229280054+ASCC2chr2230221246-0.0225020050.977498
ENST00000544604ENST00000397771ZNRF3chr2229280054+ASCC2chr2230221246-0.0220877680.9779122
ENST00000544604ENST00000542393ZNRF3chr2229280054+ASCC2chr2230221246-0.0222069290.9777931
ENST00000544604ENST00000307790ZNRF3chr2229280054+ASCC2chr2230221769-0.0172877760.98271215
ENST00000544604ENST00000397771ZNRF3chr2229280054+ASCC2chr2230221769-0.0173345320.9826654
ENST00000544604ENST00000307790ZNRF3chr2229280053+ASCC2chr2230221245-0.0225020050.977498
ENST00000544604ENST00000397771ZNRF3chr2229280053+ASCC2chr2230221245-0.0220877680.9779122
ENST00000544604ENST00000542393ZNRF3chr2229280053+ASCC2chr2230221245-0.0222069290.9777931
ENST00000544604ENST00000307790ZNRF3chr2229280053+ASCC2chr2230221768-0.0172877760.98271215
ENST00000544604ENST00000397771ZNRF3chr2229280053+ASCC2chr2230221768-0.0173345320.9826654

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Fusion Genomic Features for ZNRF3-ASCC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ZNRF3-ASCC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:29280054/chr22:30221246)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ASCC2

Q9H1I8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). {ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:29144457}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneASCC2chr22:29280053chr22:30221245ENST00000307790220467_51080758.0DomainCUE
TgeneASCC2chr22:29280053chr22:30221245ENST00000397771321467_51080758.0DomainCUE
TgeneASCC2chr22:29280053chr22:30221245ENST00000542393119467_51027682.0DomainCUE
TgeneASCC2chr22:29280053chr22:30221768ENST00000307790120467_51027758.0DomainCUE
TgeneASCC2chr22:29280053chr22:30221768ENST00000397771221467_51027758.0DomainCUE
TgeneASCC2chr22:29280053chr22:30221768ENST00000542393019467_5100682.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221246ENST00000307790220467_51080758.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221246ENST00000397771321467_51080758.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221246ENST00000542393119467_51027682.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221769ENST00000307790120467_51027758.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221769ENST00000397771221467_51027758.0DomainCUE
TgeneASCC2chr22:29280054chr22:30221769ENST00000542393019467_5100682.0DomainCUE

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneZNRF3chr22:29280053chr22:30221245ENST00000332811+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221245ENST00000332811+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221245ENST00000402174+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221245ENST00000402174+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221245ENST00000406323+18241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221245ENST00000406323+1856_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221245ENST00000544604+19241_936100937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221245ENST00000544604+1956_219100937.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221768ENST00000332811+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221768ENST00000332811+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221768ENST00000402174+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221768ENST00000402174+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221768ENST00000406323+18241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221768ENST00000406323+1856_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221768ENST00000544604+19241_936100937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280053chr22:30221768ENST00000544604+1956_219100937.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221246ENST00000332811+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221246ENST00000332811+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221246ENST00000402174+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221246ENST00000402174+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221246ENST00000406323+18241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221246ENST00000406323+1856_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221246ENST00000544604+19241_936100937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221246ENST00000544604+1956_219100937.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221769ENST00000332811+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221769ENST00000332811+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221769ENST00000402174+19241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221769ENST00000402174+1956_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221769ENST00000406323+18241_9360837.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221769ENST00000406323+1856_2190837.0Topological domainExtracellular
HgeneZNRF3chr22:29280054chr22:30221769ENST00000544604+19241_936100937.0Topological domainCytoplasmic
HgeneZNRF3chr22:29280054chr22:30221769ENST00000544604+1956_219100937.0Topological domainExtracellular
HgeneZNRF3chr22:29280053chr22:30221245ENST00000332811+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000402174+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000406323+18220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000544604+19220_240100937.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000332811+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000402174+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000406323+18220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000544604+19220_240100937.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000332811+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000402174+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000406323+18220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000544604+19220_240100937.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000332811+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000402174+19220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000406323+18220_2400837.0TransmembraneHelical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000544604+19220_240100937.0TransmembraneHelical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000332811+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000402174+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000406323+18293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221245ENST00000544604+19293_334100937.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000332811+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000402174+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000406323+18293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280053chr22:30221768ENST00000544604+19293_334100937.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000332811+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000402174+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000406323+18293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221246ENST00000544604+19293_334100937.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000332811+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000402174+19293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000406323+18293_3340837.0Zinc fingerRING-type%3B atypical
HgeneZNRF3chr22:29280054chr22:30221769ENST00000544604+19293_334100937.0Zinc fingerRING-type%3B atypical


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Fusion Gene Sequence for ZNRF3-ASCC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>103161_103161_1_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000307790_length(transcript)=2914nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAGATCACTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCT
GGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAG
TGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCAC
ACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATAC
CTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTT
CTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCT
CTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAA
CATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCC
CGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGC
ATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGT
GACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGC
CATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGA
GTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGA
CAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTC
AGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGC
ACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTA
CGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATT
CACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGC
TCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTA
CCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGC
CAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCA
GGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAA
CCCCTCAACAGCCTCAGCTTTGCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTG
CCTTATGCCACAGCCGAAGAATCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCC
AAGGCAAGCGCCCCAAACCTCGGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAG

>103161_103161_1_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000307790_length(amino acids)=777AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPK
ILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLC
DTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSC
DNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGV
TVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRN
LDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSV
YYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKK

--------------------------------------------------------------
>103161_103161_2_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000397771_length(transcript)=2880nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAGATCACTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCT
GGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAG
TGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCAC
ACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATAC
CTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTT
CTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCT
CTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAA
CATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCC
CGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGC
ATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGT
GACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGC
CATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGA
GTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGA
CAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTC
AGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGC
ACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTA
CGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATT
CACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGC
TCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTA
CCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGC
CAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCA
GGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAA
CCCCTCAACAGCCTCAGCTTTGCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTG
CCTTATGCCACAGCCGAAGAATCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCC
AAGGCAAGCGCCCCAAACCTCGGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAG

>103161_103161_2_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000397771_length(amino acids)=777AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPK
ILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLC
DTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSC
DNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGV
TVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRN
LDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSV
YYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKK

--------------------------------------------------------------
>103161_103161_3_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000542393_length(transcript)=2571nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAATCCTGGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTAC
ACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCA
AGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACAT
TGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTT
TTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCT
TGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCAT
CCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCG
GGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACAT
CCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGG
GGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGC
AGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGG
CTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAG
CCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTT
TGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAA
CGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCT
GCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGA
GCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGA
AGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGC
CTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCA
GGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGAT
CCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTA

>103161_103161_3_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221245_ENST00000542393_length(amino acids)=754AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKILDLCVLFGKGNSPLLQKMIGNI
FTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKH
DFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRF
LRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECM
GAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQND
EFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSD
DELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRET

--------------------------------------------------------------
>103161_103161_4_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221768_ENST00000307790_length(transcript)=3073nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGCACCCCGAGCAGAAGGCAGACCGGTATTTTGTGTTATACAAACCGCCCCCTAAAGACAACATTCC
CGCCCTAGTGGAGGAGTACCTGGAACGCGCCACCTTCGTAGCCAATGACCTCGACTGGCTCCTGGCCTTGCCTCACGATAAATTCTGGTG
CCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATTCGACGAGGGGGTGGCCTCAGC
CCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCACTCACAAGGAATCCAAAGATCA
CTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCTGGACCTCTGCGTGCTCTTTGG
AAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCC
TACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAG
GGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTT
TCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGA
AATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCT
AATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGA
GTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTT
GCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACG
GAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCA
AGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGA
CTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGA
GCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCC
TACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCA
CAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCA
GTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACAC
ATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAG
AACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGT
TCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGC
AGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAA
CCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGG
CACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAACCCCTCAACAGCCTCAGCTTT
GCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTGCCTTATGCCACAGCCGAAGAA
TCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCCAAGGCAAGCGCCCCAAACCTC
GGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAGTCCTGCTAATAAAATTTTTGA

>103161_103161_4_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221768_ENST00000307790_length(amino acids)=830AA_BP=100
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVA
SAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDET
LPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAI
PEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDI
SLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVE
LDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSR
VHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQV
LRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATR

--------------------------------------------------------------
>103161_103161_5_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221768_ENST00000397771_length(transcript)=3039nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGCACCCCGAGCAGAAGGCAGACCGGTATTTTGTGTTATACAAACCGCCCCCTAAAGACAACATTCC
CGCCCTAGTGGAGGAGTACCTGGAACGCGCCACCTTCGTAGCCAATGACCTCGACTGGCTCCTGGCCTTGCCTCACGATAAATTCTGGTG
CCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATTCGACGAGGGGGTGGCCTCAGC
CCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCACTCACAAGGAATCCAAAGATCA
CTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCTGGACCTCTGCGTGCTCTTTGG
AAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCC
TACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAG
GGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTT
TCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGA
AATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCT
AATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGA
GTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTT
GCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACG
GAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCA
AGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGA
CTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGA
GCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCC
TACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCA
CAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCA
GTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACAC
ATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAG
AACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGT
TCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGC
AGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAA
CCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGG
CACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAACCCCTCAACAGCCTCAGCTTT
GCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTGCCTTATGCCACAGCCGAAGAA
TCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCCAAGGCAAGCGCCCCAAACCTC

>103161_103161_5_ZNRF3-ASCC2_ZNRF3_chr22_29280053_ENST00000544604_ASCC2_chr22_30221768_ENST00000397771_length(amino acids)=830AA_BP=100
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVA
SAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDET
LPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAI
PEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDI
SLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVE
LDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSR
VHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQV
LRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATR

--------------------------------------------------------------
>103161_103161_6_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000307790_length(transcript)=2914nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAGATCACTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCT
GGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAG
TGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCAC
ACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATAC
CTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTT
CTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCT
CTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAA
CATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCC
CGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGC
ATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGT
GACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGC
CATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGA
GTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGA
CAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTC
AGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGC
ACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTA
CGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATT
CACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGC
TCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTA
CCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGC
CAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCA
GGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAA
CCCCTCAACAGCCTCAGCTTTGCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTG
CCTTATGCCACAGCCGAAGAATCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCC
AAGGCAAGCGCCCCAAACCTCGGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAG

>103161_103161_6_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000307790_length(amino acids)=777AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPK
ILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLC
DTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSC
DNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGV
TVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRN
LDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSV
YYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKK

--------------------------------------------------------------
>103161_103161_7_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000397771_length(transcript)=2880nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAGATCACTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCT
GGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAG
TGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCAC
ACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATAC
CTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTT
CTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCT
CTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAA
CATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCC
CGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGC
ATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGT
GACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGC
CATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGA
GTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGA
CAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTC
AGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGC
ACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTA
CGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATT
CACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGC
TCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTA
CCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGC
CAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCA
GGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAA
CCCCTCAACAGCCTCAGCTTTGCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTG
CCTTATGCCACAGCCGAAGAATCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCC
AAGGCAAGCGCCCCAAACCTCGGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAG

>103161_103161_7_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000397771_length(amino acids)=777AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPK
ILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLC
DTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSC
DNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGV
TVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRN
LDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSV
YYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKK

--------------------------------------------------------------
>103161_103161_8_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000542393_length(transcript)=2571nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATT
CGACGAGGGGGTGGCCTCAGCCCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCAC
TCACAAGGAATCCAAAATCCTGGACCTCTGCGTGCTCTTTGGAAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTAC
ACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCCTACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCA
AGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAGGGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACAT
TGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTTTCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTT
TTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGAAATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCT
TGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCTAATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCAT
CCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGAGTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCG
GGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTTGCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACAT
CCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACGGAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGG
GGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCAAGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGC
AGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGACTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGG
CTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGAGCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAG
CCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCCTACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTT
TGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCACAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAA
CGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCAGTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCT
GCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACACATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGA
GCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAGAACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGA
AGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGTTCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGC
CTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGCAGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCA
GGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAACCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGAT
CCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGGCACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTA

>103161_103161_8_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221246_ENST00000542393_length(amino acids)=754AA_BP=98
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKILDLCVLFGKGNSPLLQKMIGNI
FTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKH
DFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRF
LRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECM
GAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQND
EFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSD
DELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRET

--------------------------------------------------------------
>103161_103161_9_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221769_ENST00000307790_length(transcript)=3073nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGCACCCCGAGCAGAAGGCAGACCGGTATTTTGTGTTATACAAACCGCCCCCTAAAGACAACATTCC
CGCCCTAGTGGAGGAGTACCTGGAACGCGCCACCTTCGTAGCCAATGACCTCGACTGGCTCCTGGCCTTGCCTCACGATAAATTCTGGTG
CCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATTCGACGAGGGGGTGGCCTCAGC
CCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCACTCACAAGGAATCCAAAGATCA
CTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCTGGACCTCTGCGTGCTCTTTGG
AAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCC
TACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAG
GGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTT
TCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGA
AATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCT
AATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGA
GTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTT
GCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACG
GAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCA
AGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGA
CTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGA
GCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCC
TACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCA
CAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCA
GTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACAC
ATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAG
AACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGT
TCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGC
AGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAA
CCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGG
CACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAACCCCTCAACAGCCTCAGCTTT
GCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTGCCTTATGCCACAGCCGAAGAA
TCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCCAAGGCAAGCGCCCCAAACCTC
GGGCCACAAGACACCACTTCCCCTTTACCCTGGACAGCAGGAAACCTGTATATTCAAAAACACAAAAAGTCCTGCTAATAAAATTTTTGA

>103161_103161_9_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221769_ENST00000307790_length(amino acids)=830AA_BP=100
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVA
SAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDET
LPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAI
PEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDI
SLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVE
LDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSR
VHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQV
LRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATR

--------------------------------------------------------------
>103161_103161_10_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221769_ENST00000397771_length(transcript)=3039nt_BP=475nt
AGATGAAAGGGCCGCGGCGCGACGGCCGGGGGAGCCGAGCTGAGCCTGCGACCCACAAAGCCGCCGCCGCCGCCGCCGTGATGGGGCTGT
GAGGCGTCCGCCCGCGTTCGGTCCTCAGCCGGCCCGCGACTATGCCCGGCCGCGCCCGCCCTCCGCGCCCTCCCGCCGCAGGACCATGAG
GCCGCGCTCGGGCGGGCGCCCAGGGGCCACGGGCCGCCGCCGCCGCCGCCTGCGCCGCCGCCCCCGCGGCCTCCGGTGCAGCCGCCTGCC
GCCGCCGCCGCCGCTGCCGCTGCTGCTCGGGCTGCTGCTGGCGGCCGCGGGGCCCGGCGCGGCGCGGGCCAAGGAGACGGCGTTCGTGGA
GGTGGTGCTGTTCGAGTCGAGCCCAAGCGGCGATTACACCACCTACACCACCGGCCTCACGGGCCGCTTCTCGCGGGCCGGGGCCACGCT
CAGCGCCGAGGGCGAGATCGTGCAGCACCCCGAGCAGAAGGCAGACCGGTATTTTGTGTTATACAAACCGCCCCCTAAAGACAACATTCC
CGCCCTAGTGGAGGAGTACCTGGAACGCGCCACCTTCGTAGCCAATGACCTCGACTGGCTCCTGGCCTTGCCTCACGATAAATTCTGGTG
CCAGGTGATCTTTGACGAGACTCTACAGAAGTGCCTGGACTCCTACCTGCGCTATGTCCCCCGCAAATTCGACGAGGGGGTGGCCTCAGC
CCCTGAGGTTGTTGACATGCAGAAGCGCCTCCATCGAAGTGTTTTTCTCACCTTCCTCCGCATGTCCACTCACAAGGAATCCAAAGATCA
CTTCATTTCCCCTTCTGCGTTTGGAGAAATCCTCTACAATAACTTCCTCTTTGACATTCCAAAGATCCTGGACCTCTGCGTGCTCTTTGG
AAAAGGCAACTCACCACTGCTCCAGAAGATGATAGGAAACATCTTTACACAGCAGCCAAGTTACTACAGTGACCTGGATGAAACCCTGCC
TACCATCCTTCAGGTCTTCAGCAATATCCTCCAGCACTGTGGTTTGCAAGGGGACGGGGCCAATACCACACCCCAGAAGCTTGAGGAGAG
GGGCCGATTGACCCCCAGTGACATGCCTCTCCTGGAATTAAAGGACATTGTTCTCTACCTTTGTGATACCTGCACCACACTTTGGGCCTT
TCTGGATATCTTCCCTTTGGCTTGCCAGACCTTCCAGAAGCACGACTTTTGTTACAGACTAGCTTCCTTCTACGAAGCAGCAATTCCCGA
AATGGAGTCTGCAATTAAGAAGAGGAGGCTTGAAGATAGCAAGCTTCTTGGTGACCTGTGGCAGAGGCTCTCCCATTCCAGGAAGAAGCT
AATGGAGATTTTCCACATCATCCTGAACCAGATCTGCCTCCTTCCCATCCTAGAAAGCAGCTGTGACAACATTCAGGGCTTCATCGAAGA
GTTCCTTCAGATCTTCAGCTCCTTGCTGCAGGAGAAGAGGTTCCTCCGGGACTATGATGCACTCTTCCCCGTGGCCGAAGACATCAGCTT
GCTGCAGCAGGCCTCATCAGTCTTGGACGAGACGCGGACTGCCTACATCCTCCAGGCAGTCGAGAGTGCATGGGAAGGGGTGGACAGACG
GAAAGCCACAGATGCTAAAGACCCATCGGTGATTGAGGAGCCTAATGGGGAGCCTAACGGGGTCACGGTGACAGCAGAGGCAGTCAGTCA
AGCATCATCACATCCGGAGAACTCGGAGGAAGAGGAGTGCATGGGAGCAGCCGCGGCTGTGGGCCCTGCCATGTGTGGGGTGGAACTGGA
CTCTCTCATCTCCCAAGTGAAGGACCTGCTGCCAGACCTTGGTGAGGGCTTCATCCTGGCCTGCCTGGAGTACTACCACTACGACCCAGA
GCAGGTGATCAACAATATCCTGGAGGAGCGGCTGGCCCCCACCCTCAGCCAGCTGGACCGCAACCTAGACAGAGAAATGAAACCAGACCC
TACACCCCTGCTGACGTCTCGCCACAACGTCTTCCAGAATGACGAGTTTGATGTGTTCAGCAGGGACTCAGTAGACCTGAGCCGGGTGCA
CAAGGGCAAGAGCACCAGGAAGGAGGAAAACACGCGGAGTTTGCTGAACGACAAGCGTGCAGTGGCGGCACAGCGGCAGCGCTACGAGCA
GTACAGCGTGGTGGTGGAGGAGGTGCCACTGCAGCCAGGCGAGAGCCTGCCCTACCACAGTGTCTACTACGAGGATGAGTACGATGACAC
ATACGATGGCAACCAGGTGGGCGCCAATGATGCAGACTCTGATGACGAGCTCATCAGCCGCAGGCCATTCACCATCCCTCAGGTGCTGAG
AACCAAAGTGCCTAGAGAAGGGCAGGAGGAGGATGACGACGATGAGGAAGACGATGCTGACGAGGAGGCTCCCAAGCCCGACCATTTTGT
TCAGGACCCTGCAGTGCTGAGAGAGAAGGCAGAAGCCAGGCGCATGGCCTTTCTCGCCAAGAAAGGGTACCGGCATGACAGCTCAACAGC
AGTGGCCGGCAGCCCCCGAGGCCATGGGCAGAGCCGCGAGACAACCCAGGAACGCAGGAAGAAGGAAGCCAACAAGGCGACAAGAGCCAA
CCACAACCGGAGAACCATGGCCGACCGCAAGAGGAGCAAAGGCATGATCCCATCCTGAGACCTGGTGCAGGGCCAGTGGGGAGGCAGCGG
CACCAGACTCACCAGGCCGTGCTCCCATCGCCTGGGGCCTCCTCACTAGGGGCCCCAAGTTCAACTCAACCCCTCAACAGCCTCAGCTTT
GCAGCCCCTGAGAAGGCCGCCTCTCATCTACCAGCCAGCCATGAGCGCCTTCCTGCAGAACACACAGTGCCTTATGCCACAGCCGAAGAA
TCCGTGGGGCCGGCAAGCAGGCACCTTCCCCCAGCTGCGCTAGCGGGAAAGAGATGGGGATGGAGTCCCAAGGCAAGCGCCCCAAACCTC

>103161_103161_10_ZNRF3-ASCC2_ZNRF3_chr22_29280054_ENST00000544604_ASCC2_chr22_30221769_ENST00000397771_length(amino acids)=830AA_BP=100
MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFESSPSGDYTTYTTGLTGRFSRAGA
TLSAEGEIVQHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVA
SAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDET
LPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAI
PEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDI
SLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVE
LDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSR
VHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQV
LRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ZNRF3-ASCC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ZNRF3-ASCC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZNRF3-ASCC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource