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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BTBD11-PROSER1 (FusionGDB2 ID:10437)

Fusion Gene Summary for BTBD11-PROSER1

check button Fusion gene summary
Fusion gene informationFusion gene name: BTBD11-PROSER1
Fusion gene ID: 10437
HgeneTgene
Gene symbol

BTBD11

PROSER1

Gene ID

121551

80209

Gene nameBTB domain containing 11proline and serine rich 1
SynonymsABTB2BC13orf23
Cytomap

12q23.3

13q13.3

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat and BTB/POZ domain-containing protein BTBD11ANK-repeat BTB domain containing proteinBTB (POZ) domain containing 11BTB/POZ domain-containing protein 11proline and serine-rich protein 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000280758, ENST00000420571, 
ENST00000490090, ENST00000357167, 
ENST00000494235, 		ENST00000484434, 
ENST00000350125, ENST00000352251, 
Fusion gene scores* DoF score4 X 4 X 3=486 X 5 X 2=60
# samples 46
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/60*10)=0
Context

PubMed: BTBD11 [Title/Abstract] AND PROSER1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBTBD11(107914413)-PROSER1(39591681), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BTBD11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PROSER1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-EQ-A4SO-01ABTBD11chr12

107914413

+PROSER1chr13

39591681

-


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Fusion Gene ORF analysis for BTBD11-PROSER1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000280758ENST00000484434BTBD11chr12

107914413

+PROSER1chr13

39591681

-
5CDS-intronENST00000420571ENST00000484434BTBD11chr12

107914413

+PROSER1chr13

39591681

-
5CDS-intronENST00000490090ENST00000484434BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000280758ENST00000350125BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000280758ENST00000352251BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000420571ENST00000350125BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000420571ENST00000352251BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000490090ENST00000350125BTBD11chr12

107914413

+PROSER1chr13

39591681

-
In-frameENST00000490090ENST00000352251BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-3CDSENST00000357167ENST00000350125BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-3CDSENST00000357167ENST00000352251BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-3CDSENST00000494235ENST00000350125BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-3CDSENST00000494235ENST00000352251BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-intronENST00000357167ENST00000484434BTBD11chr12

107914413

+PROSER1chr13

39591681

-
intron-intronENST00000494235ENST00000484434BTBD11chr12

107914413

+PROSER1chr13

39591681

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000280758BTBD11chr12107914413+ENST00000352251PROSER1chr1339591681-5417181352839171129
ENST00000280758BTBD11chr12107914413+ENST00000350125PROSER1chr1339591681-5417181352839171129
ENST00000420571BTBD11chr12107914413+ENST00000352251PROSER1chr1339591681-5409180552039091129
ENST00000420571BTBD11chr12107914413+ENST00000350125PROSER1chr1339591681-5409180552039091129
ENST00000490090BTBD11chr12107914413+ENST00000352251PROSER1chr1339591681-48891285033891129
ENST00000490090BTBD11chr12107914413+ENST00000350125PROSER1chr1339591681-48891285033891129

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000280758ENST00000352251BTBD11chr12107914413+PROSER1chr1339591681-0.0052327450.9947673
ENST00000280758ENST00000350125BTBD11chr12107914413+PROSER1chr1339591681-0.0052327450.9947673
ENST00000420571ENST00000352251BTBD11chr12107914413+PROSER1chr1339591681-0.0052022880.9947977
ENST00000420571ENST00000350125BTBD11chr12107914413+PROSER1chr1339591681-0.0052022880.9947977
ENST00000490090ENST00000352251BTBD11chr12107914413+PROSER1chr1339591681-0.0028243880.9971756
ENST00000490090ENST00000350125BTBD11chr12107914413+PROSER1chr1339591681-0.0028243880.9971756

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Fusion Genomic Features for BTBD11-PROSER1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for BTBD11-PROSER1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:107914413/chr13:39591681)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217280_3304281105.0Compositional biasNote=Ala-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217332_3414281105.0Compositional biasNote=His-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215280_330428986.0Compositional biasNote=Ala-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215332_341428986.0Compositional biasNote=His-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215280_3304281008.0Compositional biasNote=Ala-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215332_3414281008.0Compositional biasNote=His-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217168_1884281105.0TransmembraneHelical
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215168_188428986.0TransmembraneHelical
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215168_1884281008.0TransmembraneHelical
TgenePROSER1chr12:107914413chr13:39591681ENST00000352251813388_798243945.0Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115280_3300642.0Compositional biasNote=Ala-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115332_3410642.0Compositional biasNote=His-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17280_3300184.0Compositional biasNote=Ala-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17332_3410184.0Compositional biasNote=His-rich
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217923_9894281105.0DomainBTB
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115923_9890642.0DomainBTB
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215923_989428986.0DomainBTB
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215923_9894281008.0DomainBTB
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17923_9890184.0DomainBTB
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217603_6324281105.0RepeatNote=ANK 1
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217649_6784281105.0RepeatNote=ANK 2
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217687_7164281105.0RepeatNote=ANK 3
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217730_7594281105.0RepeatNote=ANK 4
HgeneBTBD11chr12:107914413chr13:39591681ENST00000280758+217825_8544281105.0RepeatNote=ANK 5
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115603_6320642.0RepeatNote=ANK 1
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115649_6780642.0RepeatNote=ANK 2
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115687_7160642.0RepeatNote=ANK 3
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115730_7590642.0RepeatNote=ANK 4
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115825_8540642.0RepeatNote=ANK 5
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215603_632428986.0RepeatNote=ANK 1
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215649_678428986.0RepeatNote=ANK 2
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215687_716428986.0RepeatNote=ANK 3
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215730_759428986.0RepeatNote=ANK 4
HgeneBTBD11chr12:107914413chr13:39591681ENST00000420571+215825_854428986.0RepeatNote=ANK 5
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215603_6324281008.0RepeatNote=ANK 1
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215649_6784281008.0RepeatNote=ANK 2
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215687_7164281008.0RepeatNote=ANK 3
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215730_7594281008.0RepeatNote=ANK 4
HgeneBTBD11chr12:107914413chr13:39591681ENST00000490090+215825_8544281008.0RepeatNote=ANK 5
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17603_6320184.0RepeatNote=ANK 1
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17649_6780184.0RepeatNote=ANK 2
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17687_7160184.0RepeatNote=ANK 3
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17730_7590184.0RepeatNote=ANK 4
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17825_8540184.0RepeatNote=ANK 5
HgeneBTBD11chr12:107914413chr13:39591681ENST00000357167+115168_1880642.0TransmembraneHelical
HgeneBTBD11chr12:107914413chr13:39591681ENST00000494235+17168_1880184.0TransmembraneHelical
TgenePROSER1chr12:107914413chr13:39591681ENST00000352251813185_386243945.0Compositional biasNote=Pro-rich


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Fusion Gene Sequence for BTBD11-PROSER1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10437_10437_1_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000280758_PROSER1_chr13_39591681_ENST00000350125_length(transcript)=5417nt_BP=1813nt
GGTTCGGCAAGGTTTGCAGCCGCCACGGCCGCTGCTGCGCTCCGGTGCAGGGCAGGCTGGCGCCGAGCGAACCAGGGCCGGGAACTGGGA
GCCGGGAGCCGGGAGCCAGCTGCCCGCGGAGCTGCGGCGGCGGCGGCATCTGGGGTGGTCTCAGTCCCACGAACACCGTGGCCGGCGCCC
GGTGGCTACTGCGCCCAGCGGGGCTCAGGGAAGAGCGGTCTAGACACTTTTTATTTTGGAAGAAAGGGGCAAGCCCCGGCGGGAGCTTCC
TTCCCGGCCTGGCTCGCTCCCCATTGCGCCCAGCTCCGGCCCGGACTCTGGAAGATGACTCCAGGGTCTGCTCTGTATATTCCAGCGGCG
GCAGTTCCGGGAGGCAGCCGAAAGTACTAACAGTTGGTAGCAGCGGCTAGTGGAAAAGTGAGCCAAGGCGGCGCGGACTCGGCTCTCCCC
GCGCCCCGCGGCACTCGCTGCTCCTCGCCGCTCCTTCCCTTTGGCTCCCAGGCGGCTGCAGCATGAAGTGGCGCAGCGATGGCCAGGAGA
GGTAAGAAGCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGCTCCTCCAACTTG
TCTTTGTGCTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCACAGCCGGCACAAC
AGCTTTGACACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTGCTGCCGGACCTA
GACGAGGTCCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTCCCCGGCGGCCTG
CCCAAGGACGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTGAGCCTGCGCTTC
GCCAAGTGCACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCGGCTGCGCTGGCC
GCACTGTCCCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACCTTCTCCGTGGGC
CGCGTGTATCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGCATGGAGAGCCTC
TTCCGGGACATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCCGGCCCAGGCCCG
AGCTCGGGCCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCCTGCAGCGCAGCC
AGCAGCGCCAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCCAACCACCACCAT
CACCACCACCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAGATCTGGGGTCTC
CTGCAGCCCTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCACAGAGACCCACAG
CGGTCAAACAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACGCGCGTAGGCAGC
ATCGCCGAATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGTCAACTCTTTTCT
CCTCATGGTTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCATCAGCATCAGCA
GCTGCCACCGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCACACACCTCAGCCA
TCAATACCAAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACCACTCCTGTTCCT
TCCATTTTTTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACACCACGGTCCACT
CTTGGTTCCAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCTTCTACCAGCAAC
CCAAATTCTGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAACCCGACTCCTGTA
ATTGCTGGTGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTTCTGACATCCAAT
GACACCAATTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTTCAGAACTCTGAC
TCTTCTGCTTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTGGCCCTGTTCCCA
GGCCTGCCGTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCATCAGCTTCCACG
TCAGTGCCAGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCATCTACCCCTGCT
GCAACAACTCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCTGGGAATCCCTCT
CATGGCACTTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGCCTTAATCCTGCA
TTGTCAGGTCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGTTCCTCCACTCCC
ATTGCACCAGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTTAATCCGTCAGTA
TCTCTCCCAGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCAGCTGTTCTCTCA
GGGCTTTCTGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCTGTTACTCAAGGA
CCTCTGTCATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCATTCCCGGGGCTG
CAGGCGCCCTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCAGGATTCGCCTCA
GCATTCAGTTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCTGTTTTTCCAGGC
CTTTTGTCCCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCGGCTGCGCAGTCA
GCATTGTTACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCTTCAGCGCCAGGA
ACACCATTTTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGCAACATCAGAATT
GCCTGAGAACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGGAGAAATTGTGAC
AACAATTTGAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGAGAATGGTATTTA
AAAAGTGTTTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAGAGTAGGTTGAAC
TCTTTATAGCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGGGGGTTGCATGTG
GCCCTGGGGGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTATCCACAAAAGGG
AACTTGAGACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCAGGTAAGTGAAAG
TGGTGCTTAATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAGAAATACAAGTAA
GACTTAGGATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTCTTGGGCCACCTC
TGTTACTTACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGTCAAATGCTTATA
TGAAATATGTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGGTAGTATAACATG
AGTGAATGTCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGTGATTAAAAGTGT
AAACTATAGACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGCTAATGTATTTTA
CTTCAACATAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAACTATGGATATGAC
AAATATTCTGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTTTTATCCAAATTT
AGTTGTAACTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATGAACAGACAGATT
TATGTCTTTAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAATCTATACCCATA

>10437_10437_1_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000280758_PROSER1_chr13_39591681_ENST00000350125_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

--------------------------------------------------------------
>10437_10437_2_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000280758_PROSER1_chr13_39591681_ENST00000352251_length(transcript)=5417nt_BP=1813nt
GGTTCGGCAAGGTTTGCAGCCGCCACGGCCGCTGCTGCGCTCCGGTGCAGGGCAGGCTGGCGCCGAGCGAACCAGGGCCGGGAACTGGGA
GCCGGGAGCCGGGAGCCAGCTGCCCGCGGAGCTGCGGCGGCGGCGGCATCTGGGGTGGTCTCAGTCCCACGAACACCGTGGCCGGCGCCC
GGTGGCTACTGCGCCCAGCGGGGCTCAGGGAAGAGCGGTCTAGACACTTTTTATTTTGGAAGAAAGGGGCAAGCCCCGGCGGGAGCTTCC
TTCCCGGCCTGGCTCGCTCCCCATTGCGCCCAGCTCCGGCCCGGACTCTGGAAGATGACTCCAGGGTCTGCTCTGTATATTCCAGCGGCG
GCAGTTCCGGGAGGCAGCCGAAAGTACTAACAGTTGGTAGCAGCGGCTAGTGGAAAAGTGAGCCAAGGCGGCGCGGACTCGGCTCTCCCC
GCGCCCCGCGGCACTCGCTGCTCCTCGCCGCTCCTTCCCTTTGGCTCCCAGGCGGCTGCAGCATGAAGTGGCGCAGCGATGGCCAGGAGA
GGTAAGAAGCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGCTCCTCCAACTTG
TCTTTGTGCTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCACAGCCGGCACAAC
AGCTTTGACACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTGCTGCCGGACCTA
GACGAGGTCCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTCCCCGGCGGCCTG
CCCAAGGACGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTGAGCCTGCGCTTC
GCCAAGTGCACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCGGCTGCGCTGGCC
GCACTGTCCCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACCTTCTCCGTGGGC
CGCGTGTATCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGCATGGAGAGCCTC
TTCCGGGACATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCCGGCCCAGGCCCG
AGCTCGGGCCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCCTGCAGCGCAGCC
AGCAGCGCCAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCCAACCACCACCAT
CACCACCACCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAGATCTGGGGTCTC
CTGCAGCCCTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCACAGAGACCCACAG
CGGTCAAACAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACGCGCGTAGGCAGC
ATCGCCGAATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGTCAACTCTTTTCT
CCTCATGGTTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCATCAGCATCAGCA
GCTGCCACCGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCACACACCTCAGCCA
TCAATACCAAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACCACTCCTGTTCCT
TCCATTTTTTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACACCACGGTCCACT
CTTGGTTCCAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCTTCTACCAGCAAC
CCAAATTCTGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAACCCGACTCCTGTA
ATTGCTGGTGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTTCTGACATCCAAT
GACACCAATTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTTCAGAACTCTGAC
TCTTCTGCTTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTGGCCCTGTTCCCA
GGCCTGCCGTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCATCAGCTTCCACG
TCAGTGCCAGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCATCTACCCCTGCT
GCAACAACTCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCTGGGAATCCCTCT
CATGGCACTTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGCCTTAATCCTGCA
TTGTCAGGTCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGTTCCTCCACTCCC
ATTGCACCAGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTTAATCCGTCAGTA
TCTCTCCCAGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCAGCTGTTCTCTCA
GGGCTTTCTGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCTGTTACTCAAGGA
CCTCTGTCATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCATTCCCGGGGCTG
CAGGCGCCCTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCAGGATTCGCCTCA
GCATTCAGTTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCTGTTTTTCCAGGC
CTTTTGTCCCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCGGCTGCGCAGTCA
GCATTGTTACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCTTCAGCGCCAGGA
ACACCATTTTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGCAACATCAGAATT
GCCTGAGAACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGGAGAAATTGTGAC
AACAATTTGAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGAGAATGGTATTTA
AAAAGTGTTTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAGAGTAGGTTGAAC
TCTTTATAGCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGGGGGTTGCATGTG
GCCCTGGGGGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTATCCACAAAAGGG
AACTTGAGACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCAGGTAAGTGAAAG
TGGTGCTTAATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAGAAATACAAGTAA
GACTTAGGATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTCTTGGGCCACCTC
TGTTACTTACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGTCAAATGCTTATA
TGAAATATGTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGGTAGTATAACATG
AGTGAATGTCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGTGATTAAAAGTGT
AAACTATAGACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGCTAATGTATTTTA
CTTCAACATAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAACTATGGATATGAC
AAATATTCTGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTTTTATCCAAATTT
AGTTGTAACTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATGAACAGACAGATT
TATGTCTTTAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAATCTATACCCATA

>10437_10437_2_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000280758_PROSER1_chr13_39591681_ENST00000352251_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

--------------------------------------------------------------
>10437_10437_3_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000420571_PROSER1_chr13_39591681_ENST00000350125_length(transcript)=5409nt_BP=1805nt
AAGGTTTGCAGCCGCCACGGCCGCTGCTGCGCTCCGGTGCAGGGCAGGCTGGCGCCGAGCGAACCAGGGCCGGGAACTGGGAGCCGGGAG
CCGGGAGCCAGCTGCCCGCGGAGCTGCGGCGGCGGCGGCATCTGGGGTGGTCTCAGTCCCACGAACACCGTGGCCGGCGCCCGGTGGCTA
CTGCGCCCAGCGGGGCTCAGGGAAGAGCGGTCTAGACACTTTTTATTTTGGAAGAAAGGGGCAAGCCCCGGCGGGAGCTTCCTTCCCGGC
CTGGCTCGCTCCCCATTGCGCCCAGCTCCGGCCCGGACTCTGGAAGATGACTCCAGGGTCTGCTCTGTATATTCCAGCGGCGGCAGTTCC
GGGAGGCAGCCGAAAGTACTAACAGTTGGTAGCAGCGGCTAGTGGAAAAGTGAGCCAAGGCGGCGCGGACTCGGCTCTCCCCGCGCCCCG
CGGCACTCGCTGCTCCTCGCCGCTCCTTCCCTTTGGCTCCCAGGCGGCTGCAGCATGAAGTGGCGCAGCGATGGCCAGGAGAGGTAAGAA
GCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGCTCCTCCAACTTGTCTTTGTG
CTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCACAGCCGGCACAACAGCTTTGA
CACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTGCTGCCGGACCTAGACGAGGT
CCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTCCCCGGCGGCCTGCCCAAGGA
CGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTGAGCCTGCGCTTCGCCAAGTG
CACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCGGCTGCGCTGGCCGCACTGTC
CCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACCTTCTCCGTGGGCCGCGTGTA
TCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGCATGGAGAGCCTCTTCCGGGA
CATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCCGGCCCAGGCCCGAGCTCGGG
CCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCCTGCAGCGCAGCCAGCAGCGC
CAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCCAACCACCACCATCACCACCA
CCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAGATCTGGGGTCTCCTGCAGCC
CTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCACAGAGACCCACAGCGGTCAAA
CAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACGCGCGTAGGCAGCATCGCCGA
ATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGTCAACTCTTTTCTCCTCATGG
TTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCATCAGCATCAGCAGCTGCCAC
CGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCACACACCTCAGCCATCAATACC
AAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACCACTCCTGTTCCTTCCATTTT
TTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACACCACGGTCCACTCTTGGTTC
CAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCTTCTACCAGCAACCCAAATTC
TGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAACCCGACTCCTGTAATTGCTGG
TGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTTCTGACATCCAATGACACCAA
TTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTTCAGAACTCTGACTCTTCTGC
TTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTGGCCCTGTTCCCAGGCCTGCC
GTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCATCAGCTTCCACGTCAGTGCC
AGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCATCTACCCCTGCTGCAACAAC
TCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCTGGGAATCCCTCTCATGGCAC
TTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGCCTTAATCCTGCATTGTCAGG
TCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGTTCCTCCACTCCCATTGCACC
AGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTTAATCCGTCAGTATCTCTCCC
AGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCAGCTGTTCTCTCAGGGCTTTC
TGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCTGTTACTCAAGGACCTCTGTC
ATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCATTCCCGGGGCTGCAGGCGCC
CTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCAGGATTCGCCTCAGCATTCAG
TTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCTGTTTTTCCAGGCCTTTTGTC
CCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCGGCTGCGCAGTCAGCATTGTT
ACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCTTCAGCGCCAGGAACACCATT
TTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGCAACATCAGAATTGCCTGAGA
ACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGGAGAAATTGTGACAACAATTT
GAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGAGAATGGTATTTAAAAAGTGT
TTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAGAGTAGGTTGAACTCTTTATA
GCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGGGGGTTGCATGTGGCCCTGGG
GGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTATCCACAAAAGGGAACTTGAG
ACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCAGGTAAGTGAAAGTGGTGCTT
AATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAGAAATACAAGTAAGACTTAGG
ATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTCTTGGGCCACCTCTGTTACTT
ACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGTCAAATGCTTATATGAAATAT
GTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGGTAGTATAACATGAGTGAATG
TCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGTGATTAAAAGTGTAAACTATA
GACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGCTAATGTATTTTACTTCAACA
TAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAACTATGGATATGACAAATATTC
TGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTTTTATCCAAATTTAGTTGTAA
CTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATGAACAGACAGATTTATGTCTT
TAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAATCTATACCCATAAAACTTCT

>10437_10437_3_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000420571_PROSER1_chr13_39591681_ENST00000350125_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

--------------------------------------------------------------
>10437_10437_4_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000420571_PROSER1_chr13_39591681_ENST00000352251_length(transcript)=5409nt_BP=1805nt
AAGGTTTGCAGCCGCCACGGCCGCTGCTGCGCTCCGGTGCAGGGCAGGCTGGCGCCGAGCGAACCAGGGCCGGGAACTGGGAGCCGGGAG
CCGGGAGCCAGCTGCCCGCGGAGCTGCGGCGGCGGCGGCATCTGGGGTGGTCTCAGTCCCACGAACACCGTGGCCGGCGCCCGGTGGCTA
CTGCGCCCAGCGGGGCTCAGGGAAGAGCGGTCTAGACACTTTTTATTTTGGAAGAAAGGGGCAAGCCCCGGCGGGAGCTTCCTTCCCGGC
CTGGCTCGCTCCCCATTGCGCCCAGCTCCGGCCCGGACTCTGGAAGATGACTCCAGGGTCTGCTCTGTATATTCCAGCGGCGGCAGTTCC
GGGAGGCAGCCGAAAGTACTAACAGTTGGTAGCAGCGGCTAGTGGAAAAGTGAGCCAAGGCGGCGCGGACTCGGCTCTCCCCGCGCCCCG
CGGCACTCGCTGCTCCTCGCCGCTCCTTCCCTTTGGCTCCCAGGCGGCTGCAGCATGAAGTGGCGCAGCGATGGCCAGGAGAGGTAAGAA
GCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGCTCCTCCAACTTGTCTTTGTG
CTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCACAGCCGGCACAACAGCTTTGA
CACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTGCTGCCGGACCTAGACGAGGT
CCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTCCCCGGCGGCCTGCCCAAGGA
CGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTGAGCCTGCGCTTCGCCAAGTG
CACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCGGCTGCGCTGGCCGCACTGTC
CCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACCTTCTCCGTGGGCCGCGTGTA
TCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGCATGGAGAGCCTCTTCCGGGA
CATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCCGGCCCAGGCCCGAGCTCGGG
CCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCCTGCAGCGCAGCCAGCAGCGC
CAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCCAACCACCACCATCACCACCA
CCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAGATCTGGGGTCTCCTGCAGCC
CTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCACAGAGACCCACAGCGGTCAAA
CAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACGCGCGTAGGCAGCATCGCCGA
ATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGTCAACTCTTTTCTCCTCATGG
TTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCATCAGCATCAGCAGCTGCCAC
CGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCACACACCTCAGCCATCAATACC
AAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACCACTCCTGTTCCTTCCATTTT
TTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACACCACGGTCCACTCTTGGTTC
CAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCTTCTACCAGCAACCCAAATTC
TGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAACCCGACTCCTGTAATTGCTGG
TGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTTCTGACATCCAATGACACCAA
TTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTTCAGAACTCTGACTCTTCTGC
TTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTGGCCCTGTTCCCAGGCCTGCC
GTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCATCAGCTTCCACGTCAGTGCC
AGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCATCTACCCCTGCTGCAACAAC
TCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCTGGGAATCCCTCTCATGGCAC
TTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGCCTTAATCCTGCATTGTCAGG
TCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGTTCCTCCACTCCCATTGCACC
AGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTTAATCCGTCAGTATCTCTCCC
AGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCAGCTGTTCTCTCAGGGCTTTC
TGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCTGTTACTCAAGGACCTCTGTC
ATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCATTCCCGGGGCTGCAGGCGCC
CTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCAGGATTCGCCTCAGCATTCAG
TTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCTGTTTTTCCAGGCCTTTTGTC
CCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCGGCTGCGCAGTCAGCATTGTT
ACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCTTCAGCGCCAGGAACACCATT
TTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGCAACATCAGAATTGCCTGAGA
ACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGGAGAAATTGTGACAACAATTT
GAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGAGAATGGTATTTAAAAAGTGT
TTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAGAGTAGGTTGAACTCTTTATA
GCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGGGGGTTGCATGTGGCCCTGGG
GGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTATCCACAAAAGGGAACTTGAG
ACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCAGGTAAGTGAAAGTGGTGCTT
AATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAGAAATACAAGTAAGACTTAGG
ATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTCTTGGGCCACCTCTGTTACTT
ACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGTCAAATGCTTATATGAAATAT
GTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGGTAGTATAACATGAGTGAATG
TCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGTGATTAAAAGTGTAAACTATA
GACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGCTAATGTATTTTACTTCAACA
TAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAACTATGGATATGACAAATATTC
TGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTTTTATCCAAATTTAGTTGTAA
CTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATGAACAGACAGATTTATGTCTT
TAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAATCTATACCCATAAAACTTCT

>10437_10437_4_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000420571_PROSER1_chr13_39591681_ENST00000352251_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

--------------------------------------------------------------
>10437_10437_5_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000490090_PROSER1_chr13_39591681_ENST00000350125_length(transcript)=4889nt_BP=1285nt
ATGGCCAGGAGAGGTAAGAAGCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGC
TCCTCCAACTTGTCTTTGTGCTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCAC
AGCCGGCACAACAGCTTTGACACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTG
CTGCCGGACCTAGACGAGGTCCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTC
CCCGGCGGCCTGCCCAAGGACGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTG
AGCCTGCGCTTCGCCAAGTGCACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCG
GCTGCGCTGGCCGCACTGTCCCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACC
TTCTCCGTGGGCCGCGTGTATCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGC
ATGGAGAGCCTCTTCCGGGACATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCC
GGCCCAGGCCCGAGCTCGGGCCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCC
TGCAGCGCAGCCAGCAGCGCCAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCC
AACCACCACCATCACCACCACCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAG
ATCTGGGGTCTCCTGCAGCCCTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCAC
AGAGACCCACAGCGGTCAAACAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACG
CGCGTAGGCAGCATCGCCGAATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGT
CAACTCTTTTCTCCTCATGGTTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCA
TCAGCATCAGCAGCTGCCACCGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCAC
ACACCTCAGCCATCAATACCAAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACC
ACTCCTGTTCCTTCCATTTTTTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACA
CCACGGTCCACTCTTGGTTCCAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCT
TCTACCAGCAACCCAAATTCTGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAAC
CCGACTCCTGTAATTGCTGGTGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTT
CTGACATCCAATGACACCAATTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTT
CAGAACTCTGACTCTTCTGCTTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTG
GCCCTGTTCCCAGGCCTGCCGTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCA
TCAGCTTCCACGTCAGTGCCAGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCA
TCTACCCCTGCTGCAACAACTCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCT
GGGAATCCCTCTCATGGCACTTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGC
CTTAATCCTGCATTGTCAGGTCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGT
TCCTCCACTCCCATTGCACCAGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTT
AATCCGTCAGTATCTCTCCCAGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCA
GCTGTTCTCTCAGGGCTTTCTGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCT
GTTACTCAAGGACCTCTGTCATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCA
TTCCCGGGGCTGCAGGCGCCCTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCA
GGATTCGCCTCAGCATTCAGTTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCT
GTTTTTCCAGGCCTTTTGTCCCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCG
GCTGCGCAGTCAGCATTGTTACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCT
TCAGCGCCAGGAACACCATTTTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGC
AACATCAGAATTGCCTGAGAACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGG
AGAAATTGTGACAACAATTTGAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGA
GAATGGTATTTAAAAAGTGTTTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAG
AGTAGGTTGAACTCTTTATAGCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGG
GGGTTGCATGTGGCCCTGGGGGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTA
TCCACAAAAGGGAACTTGAGACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCA
GGTAAGTGAAAGTGGTGCTTAATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAG
AAATACAAGTAAGACTTAGGATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTC
TTGGGCCACCTCTGTTACTTACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGT
CAAATGCTTATATGAAATATGTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGG
TAGTATAACATGAGTGAATGTCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGT
GATTAAAAGTGTAAACTATAGACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGC
TAATGTATTTTACTTCAACATAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAAC
TATGGATATGACAAATATTCTGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTT
TTATCCAAATTTAGTTGTAACTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATG
AACAGACAGATTTATGTCTTTAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAA

>10437_10437_5_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000490090_PROSER1_chr13_39591681_ENST00000350125_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

--------------------------------------------------------------
>10437_10437_6_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000490090_PROSER1_chr13_39591681_ENST00000352251_length(transcript)=4889nt_BP=1285nt
ATGGCCAGGAGAGGTAAGAAGCCCGTGGTGAGAACGCTGGAGGATCTGACGCTGGACTCGGGTTATGGTGGCGCGGCGGACTCGGTGCGC
TCCTCCAACTTGTCTTTGTGCTGTTCCGACTCGCACCCGGCGTCCCCGTATGGCGGGAGCTGCTGGCCGCCTCTAGCTGACTCCATGCAC
AGCCGGCACAACAGCTTTGACACTGTCAACACTGCCCTGGTGGAAGACTCCGAGGGGCTGGACTGCGCCGGCCAGCACTGCTCGCGGCTG
CTGCCGGACCTAGACGAGGTCCCCTGGACTCTCCAGGAGCTGGAGGCGCTGCTGCTGCGTTCGCGGGATCCCCGGGCAGGCCCGGCGGTC
CCCGGCGGCCTGCCCAAGGACGCGCTGGCCAAGCTGTCGACGCTGGTGAGCCGGGCGCTGGTGCGCATAGCCAAAGAGGCGCAGCGCCTG
AGCCTGCGCTTCGCCAAGTGCACCAAGTACGAGATCCAGAGCGCCATGGAGATCGTGCTGTCCTGGGGCCTGGCCGCGCACTGTACGGCG
GCTGCGCTGGCCGCACTGTCCCTCTACAACATGAGCAGCGCCGGCGGCGACCGCCTGGGCCGCGGCAAGTCGGCCCGCTGCGGCCTCACC
TTCTCCGTGGGCCGCGTGTATCGCTGGATGGTGGACAGCCGCGTGGCGCTGCGCATCCACGAGCACGCCGCCATCTACCTGACAGCCTGC
ATGGAGAGCCTCTTCCGGGACATCTACTCGCGGGTCGTGGCCTCCGGGGTGCCCCGGAGCTGCAGTGGCCCTGGGTCAGGCTCGGGCTCC
GGCCCAGGCCCGAGCTCGGGCCCTGGTGCGGCCCCCGCGGCGGATAAAGAGCGGGAGGCGCCCGGGGGAGGAGCGGCGAGCGGCGGCGCC
TGCAGCGCAGCCAGCAGCGCCAGCGGGGGCAGCAGCTGTTGCGCCCCGCCGGCCGCCGCGGCCGCCGCAGTCCCGCCGGCAGCCGCCGCC
AACCACCACCATCACCACCACCATGCGCTCCACGAGGCGCCCAAGTTCACCGTGGAGACCCTGGAGCACACGGTCAACAACGACTCGGAG
ATCTGGGGTCTCCTGCAGCCCTACCAGCACCTGATCTGCGGGAAGAACGCCAGCGGGGTGCTGTGCCTACCAGACAGCCTGAATCTTCAC
AGAGACCCACAGCGGTCAAACAAGCCAGGGGAACTGCCCATGTTCAGCCAGTCGGAGCTGAGGACCATCGAGCAGTCTTTGCTGGCCACG
CGCGTAGGCAGCATCGCCGAATTGAAGAATGAAGACCTTTCGAATCCGTCAAAACCTATACAGAATCAAACATTTTCCACCCCAGCAAGT
CAACTCTTTTCTCCTCATGGTTCTAATCCTTCAACACCTGCTGCAACTCCTGTTCCTACTGCATCCCCAGTCAAGGCAATTAATCATCCA
TCAGCATCAGCAGCTGCCACCGTTTCTGGAATGAACCTGCTGAATACTGTCCTTCCTGTGTTCCCAGGGCAGGTCTCCTCAGCCGTTCAC
ACACCTCAGCCATCAATACCAAACCCAACAGTTATCAGAACCCCTTCATTGCCCACTGCACCTGTTACATCCATCCACAGTACAACCACC
ACTCCTGTTCCTTCCATTTTTTCTGGCCTAGTGTCACTGCCAGGTCCTTCTGCCACTCCTACCGCAGCCACTCCTACCCCAGGACCTACA
CCACGGTCCACTCTTGGTTCCAGTGAAGCATTTGCTTCTACTTCTGCACCTTTCACTAGCCTCCCCTTTTCCACCAGCTCTTCTGCTGCT
TCTACCAGCAACCCAAATTCTGCTTCATTGTCATCAGTTTTTGCAGGGCTCCCTTTGCCCTTACCACCAACATCCCAAGGCCTATCCAAC
CCGACTCCTGTAATTGCTGGTGGCTCTACTCCCAGCGTTGCCGGTCCACTTGGTGTGAACAGTCCTCTTTTGTCTGCGTTAAAAGGTTTT
CTGACATCCAATGACACCAATTTAATCAACTCCTCTGCTTTATCCTCTGCTGTCACAAGTGGGCTGGCTTCACTATCTTCTCTTACTCTT
CAGAACTCTGACTCTTCTGCTTCAGCCCCTAACAAGTGCTATGCCCCATCAGCCATCCCTACCCCACAGAGGACTTCCACTCCAGGGTTG
GCCCTGTTCCCAGGCCTGCCGTCTCCCGTGGCTAACTCAACTTCCACTCCCCTGACATTGCCTGTACAGTCTCCTTTAGCCACTGCTGCA
TCAGCTTCCACGTCAGTGCCAGTTAGCTGTGGCTCCTCAGCCTCCCTTTTGCGTGGCCCCCACCCAGGTACCTCAGATCTGCATATTTCA
TCTACCCCTGCTGCAACAACTCTTCCTGTTATGATCAAAACTGAGCCCACAAGTCCTACTCCCTCGGCCTTCAAAGGTCCATCTCATTCT
GGGAATCCCTCTCATGGCACTTTAGGTTTGTCAGGGACATTGGGCCGTGCATATACTTCAACATCCGTGCCCATCAGTTTATCTGCTTGC
CTTAATCCTGCATTGTCAGGTCTCTCCAGCTTGAGTACTCCTTTAAATGGTTCAAATCCTCTTTCCTCTATTTCCCTTCCACCACATGGT
TCCTCCACTCCCATTGCACCAGTATTCACTGCTCTTCCTTCTTTTACTTCTTTGACCAACAATTTTCCTTTAACTGGCAACCCATCTCTT
AATCCGTCAGTATCTCTCCCAGGGTCATTAATAGCCACCTCATCTACCGCTGCCACCTCCACATCTCTCCCTCATCCTAGCTCAACGGCA
GCTGTTCTCTCAGGGCTTTCTGCTTCAGCACCAGTCTCAGCAGCACCTTTCCCCCTCAACCTGTCCACTGCTGTTCCCTCACTTTTCTCT
GTTACTCAAGGACCTCTGTCATCTTCAAATCCCTCCTATCCAGGCTTTTCTGTCTCTAATACCCCAAGCGTTACCCCTGCTCTTCCCTCA
TTCCCGGGGCTGCAGGCGCCCTCTACAGTCGCAGCTGTCACACCACTACCTGTGGCTGCCACAGCCCCATCCCCAGCTCCAGTCCTCCCA
GGATTCGCCTCAGCATTCAGTTCCAATTTCAACTCCGCTCTTGTTGCACAAGCCGGTTTATCATCTGGACTTCAAGCTGCAGGCAGTTCT
GTTTTTCCAGGCCTTTTGTCCCTCCCGGGTATCCCTGGGTTTCCTCAGAATCCTTCACAATCATCCTTGCAAGAATTACAGCATAATGCG
GCTGCGCAGTCAGCATTGTTACAGCAGGTCCATTCAGCTTCGGCTCTGGAAAGCTATCCAGCTCAGCCTGATGGGTTTCCTAGTTATCCT
TCAGCGCCAGGAACACCATTTTCTTTGCAACCAAGCCTGTCCCAGAGTGGGTGGCAGTGAATACTTTTAACTTTTATTCTCCTTCAGAGC
AACATCAGAATTGCCTGAGAACTGCAATGAACAATCTGACAAATGTGAAGCTGGCCAAAAGTCGGAAAATGAGAATGAGGGTAATCCTGG
AGAAATTGTGACAACAATTTGAAAATTGTGGTTGCATTTTAAAGTGTGAACACTCCCCTATGTAAATATGCTGACAATAAATTGTATGGA
GAATGGTATTTAAAAAGTGTTTGGAGACTTTTCACCTGTCCTATAAAATTTTGAATTGTGTATGTGATCTACATAGAAAGAATATTAAAG
AGTAGGTTGAACTCTTTATAGCCGAATACAGCCTTAAATATGCTTGTATAGCATCCACTGGCAGAAGTAATAGTTGTGCCTCAGACTTGG
GGGTTGCATGTGGCCCTGGGGGAGTTACTACCCTTGGTATGCATGAGCGGTTCCTATTAGCATCAGTGGGAACTCAGTACTCTGTATGTA
TCCACAAAAGGGAACTTGAGACCCACAGTTATTCTTAATTTCTGATATTAACAACCGTACATACTGCTGAATTTAACTCAAAATATTTCA
GGTAAGTGAAAGTGGTGCTTAATGTAGACTATAGAATGACTTTCAGGTGTTTTCAACTGAAAGTATATATCCAGAACTGCATCCTTATAG
AAATACAAGTAAGACTTAGGATAATTTGCCTTCAAAACAGTTTTCCTAATCTCAGCAGTATCCAGTGAGTGAAGAACACTTGACTGACTC
TTGGGCCACCTCTGTTACTTACTGTACTATGGAAGCTCCTGGTGAATGTTTACAATTATGGGATGTAGTATTTCTATTTGTACTTTAAGT
CAAATGCTTATATGAAATATGTGACAACAAATAGAGAAGACTGGCTCTGTTAGTAATTATGCAGTATGTACTCTATTTAAGGATCTGTGG
TAGTATAACATGAGTGAATGTCATTAATTTTGAAGTAATAACTGCCACATGTGGGAAGTAGGGGAGTAAGGAGAATGAATTCCAATCTGT
GATTAAAAGTGTAAACTATAGACTCTACTGTAGTACATTTCAGGATCTAGAAGTTTTACTTTTATAAAGATGGTGTCCGGAAGATGTTGC
TAATGTATTTTACTTCAACATAGGGAACAAACTTTTTAAGTATATTAATAAACCTGTATGGTTAGTTTTTAACAGTTTTTTAAAATAAAC
TATGGATATGACAAATATTCTGTGTTTTACTAAGTGCTTGGATAGGCTTTCTAATTTTGTATACGTGCTAGAGTTAATTATTGAACATTT
TTATCCAAATTTAGTTGTAACTCTGTTTATACTACTGATTGCTCATTCGTTTAAATGATATTTTAATGTAAAAGTCATAACCAACATATG
AACAGACAGATTTATGTCTTTAAACACAGAATGTAAGCTATAGTTTAATCTGATACCAGTTGCTGGAAGTTGCCATTTGTTTTTCTTAAA

>10437_10437_6_BTBD11-PROSER1_BTBD11_chr12_107914413_ENST00000490090_PROSER1_chr13_39591681_ENST00000352251_length(amino acids)=1129AA_BP=429
MARRGKKPVVRTLEDLTLDSGYGGAADSVRSSNLSLCCSDSHPASPYGGSCWPPLADSMHSRHNSFDTVNTALVEDSEGLDCAGQHCSRL
LPDLDEVPWTLQELEALLLRSRDPRAGPAVPGGLPKDALAKLSTLVSRALVRIAKEAQRLSLRFAKCTKYEIQSAMEIVLSWGLAAHCTA
AALAALSLYNMSSAGGDRLGRGKSARCGLTFSVGRVYRWMVDSRVALRIHEHAAIYLTACMESLFRDIYSRVVASGVPRSCSGPGSGSGS
GPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSCCAPPAAAAAAVPPAAAANHHHHHHHALHEAPKFTVETLEHTVNNDSE
IWGLLQPYQHLICGKNASGVLCLPDSLNLHRDPQRSNKPGELPMFSQSELRTIEQSLLATRVGSIAELKNEDLSNPSKPIQNQTFSTPAS
QLFSPHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTT
TPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSN
PTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGL
ALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHS
GNPSHGTLGLSGTLGRAYTSTSVPISLSACLNPALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSL
NPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSVTPALPS
FPGLQAPSTVAAVTPLPVAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQHNA

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Fusion Gene PPI Analysis for BTBD11-PROSER1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BTBD11-PROSER1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BTBD11-PROSER1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource