FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:C15orf41-RAC2 (FusionGDB2 ID:10954)

Fusion Gene Summary for C15orf41-RAC2

check button Fusion gene summary
Fusion gene informationFusion gene name: C15orf41-RAC2
Fusion gene ID: 10954
HgeneTgene
Gene symbol

C15orf41

RAC2

Gene ID

84529

5880

Gene namechromosome 15 open reading frame 41Rac family small GTPase 2
SynonymsHH114EN-7|Gx|HSPC022|p21-Rac2
Cytomap

15q14

22q13.1

Type of geneprotein-codingprotein-coding
Descriptionprotein C15orf41uncharacterized protein C15orf41ras-related C3 botulinum toxin substrate 2Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2)ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)small G protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000565792, ENST00000338183, 
ENST00000437989, ENST00000562489, 
ENST00000562877, ENST00000566621, 
ENST00000567389, ENST00000569302, 
ENST00000563167, 		ENST00000249071, 
ENST00000405484, ENST00000406508, 
ENST00000401529, 
Fusion gene scores* DoF score13 X 6 X 8=6247 X 5 X 6=210
# samples 138
** MAII scorelog2(13/624*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C15orf41 [Title/Abstract] AND RAC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC15orf41(37002162)-RAC2(37628958), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRAC2

GO:0060263

regulation of respiratory burst

16636067


check buttonFusion gene breakpoints across C15orf41 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RAC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-ER-A19C-06AC15orf41chr15

37002162

-RAC2chr22

37628958

-
ChimerDB4SKCMTCGA-ER-A19C-06AC15orf41chr15

37002162

+RAC2chr22

37628958

-


Top

Fusion Gene ORF analysis for C15orf41-RAC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000565792ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
3UTR-5UTRENST00000565792ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
3UTR-5UTRENST00000565792ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
3UTR-intronENST00000565792ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000338183ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000338183ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000437989ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000437989ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000562489ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000562489ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000562877ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000562877ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000566621ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000566621ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000567389ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000567389ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000569302ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-5UTRENST00000569302ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000338183ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000437989ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000562489ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000562877ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000566621ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000567389ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
5CDS-intronENST00000569302ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000338183ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000437989ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000562489ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000562877ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000566621ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000567389ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
In-frameENST00000569302ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
intron-3CDSENST00000563167ENST00000249071C15orf41chr15

37002162

+RAC2chr22

37628958

-
intron-5UTRENST00000563167ENST00000405484C15orf41chr15

37002162

+RAC2chr22

37628958

-
intron-5UTRENST00000563167ENST00000406508C15orf41chr15

37002162

+RAC2chr22

37628958

-
intron-intronENST00000563167ENST00000401529C15orf41chr15

37002162

+RAC2chr22

37628958

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000566621C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-22199661181437439
ENST00000437989C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-1986733171204395
ENST00000569302C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-2000747131218401
ENST00000567389C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-1948695961166356
ENST00000562877C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-1887634141105363
ENST00000338183C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-1923670711141356
ENST00000562489C15orf41chr1537002162+ENST00000249071RAC2chr2237628958-151025769728219

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566621ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0065151530.9934849
ENST00000437989ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0053957210.9946043
ENST00000569302ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0052301040.9947699
ENST00000567389ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0054035060.99459654
ENST00000562877ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0052677040.99473226
ENST00000338183ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0052619380.99473804
ENST00000562489ENST00000249071C15orf41chr1537002162+RAC2chr2237628958-0.0064620880.99353796

Top

Fusion Genomic Features for C15orf41-RAC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for C15orf41-RAC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:37002162/chr22:37628958)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAC2chr15:37002162chr22:37628958ENST0000024907117115_11835420.6666666666667Nucleotide bindingGTP
TgeneRAC2chr15:37002162chr22:37628958ENST000002490711757_6135420.6666666666667Nucleotide bindingGTP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAC2chr15:37002162chr22:37628958ENST000002490711732_4035420.6666666666667MotifEffector region
TgeneRAC2chr15:37002162chr22:37628958ENST000002490711710_1735420.6666666666667Nucleotide bindingGTP


Top

Fusion Gene Sequence for C15orf41-RAC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10954_10954_1_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000338183_RAC2_chr22_37628958_ENST00000249071_length(transcript)=1923nt_BP=670nt
AGATTGCATACTCAAGAAGAGGAGGAACATAAAATACGTGATGTCTTCTCTTAAGTCAATCGCAGGCCACTCTGCTGAGCATCTTCTCCC
AGGAGTACCAGAAACACATTAAAAGAACACATGCCAAACATCATACTTCGGAAGCAATTGAAAGTTATTACCAGAGGTACCTGAATGGAG
TGGTGAAAAATGGAGCTGCCCCAGTGCTCCTGGACCTGGCCAATGAGGTGGACTATGCGCCCTCATTAATGGCTCGGCTTATACTGGAGA
GGTTTCTACAGGAACACGAGGAAACTCCACCCTCCAAGTCTATTATAAATAGTATGCTACGGGACCCTTCTCAGATTCCAGATGGAGTTC
TAGCAAATCAGGTCTATCAGTGCATTGTGAACGACTGCTGTTACGGACCACTAGTGGACTGCATCAAGCATGCCATTGGTCATGAGCATG
AGGTCCTGCTGAGAGACTTGCTTCTAGAGAAAAACCTGTCCTTCCTAGATGAAGATCAGCTTCGTGCAAAGGGTTATGACAAAACACCAG
ACTTCATTTTACAAGTACCAGTTGCTGTAGAAGGGCACATAATTCACTGGATTGAAAGCAAAGCCTCATTTGGTGATGAATGTAGCCACC
ACGCCTACCTGCATGACCAGTTCTGGAGCTACTGGAATAGGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACC
TGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCT
CCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCCATCATCCTGG
TGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCC
TGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCA
TCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGA
TGGGTCTGATCCTCCAGGATCCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCCTGTGGCGTTTCTTAGCAGATG
GCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCAGGAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCC
TCATGCTCCTGCCTTCCTGAGGGCCAGAGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTTCCTGCCGTCAGTGCCAACTGCCGCAT
GTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTCTGGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGT
GTACCTTCAGGGATGGGGCTCTTACTCCCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTGCTTGCCAGAGAGTTCCTCTACCCAGC
AAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTGGAACAACATAAAACAAATTTAATTTTCTACGCCTCTGG
GGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTCTGCTGCACTCACAGGATCCTGAGCTG
CACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAAATAGAAAACCCAACTCAACCTGCTTAAG

>10954_10954_1_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000338183_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=356AA_BP=199
MLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLANEVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPS
QIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASF
GDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCP

--------------------------------------------------------------
>10954_10954_2_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000437989_RAC2_chr22_37628958_ENST00000249071_length(transcript)=1986nt_BP=733nt
CTGGTCCCTGGCCCAACATGATACTGACCAAAGCTCAGTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCC
TGAGGAAGCTGAAGCAGAGGTTTCCCAGTCAATCGCAGGCCACTCTGCTGAGCATCTTCTCCCAGGAGTACCAGAAACACATTAAAAGAA
CACATGCCAAACATCATACTTCGGAAGCAATTGAAAGTTATTACCAGAGGTACCTGAATGGAGTGGTGAAAAATGGAGCTGCCCCAGTGC
TCCTGGACCTGGCCAATGAGGTGGACTATGCGCCCTCATTAATGGCTCGGCTTATACTGGAGAGGTTTCTACAGGAACACGAGGAAACTC
CACCCTCCAAGTCTATTATAAATAGTATGCTACGGGACCCTTCTCAGATTCCAGATGGAGTTCTAGCAAATCAGGTCTATCAGTGCATTG
TGAACGACTGCTGTTACGGACCACTAGTGGACTGCATCAAGCATGCCATTGGTCATGAGCATGAGGTCCTGCTGAGAGACTTGCTTCTAG
AGAAAAACCTGTCCTTCCTAGATGAAGATCAGCTTCGTGCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGCTG
TAGAAGGGCACATAATTCACTGGATTGAAAGCAAAGCCTCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCATGACCAGTTCTGGA
GCTACTGGAATAGGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGG
AGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGA
ACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACG
ACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGACTCGG
TGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCA
CGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCCCCACC
CAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTT
CTGTACTGGAGGCCTCCTGAGGCCAGGAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGGGCCAG
AGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTTCCTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTACCCGTTCACTCCAG
TCCCACCCCACGCCTGACTCCCCTCTGGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCTTACTC
CCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTGCTTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTC
CTCTGGCCTCAGTTCTCCTCTTTTGGAACAACATAAAACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATC
TGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTCTGCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTT
TTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAAATAGAAAACCCAACTCAACCTGCTTAAGCAGAAAATAAATTTATTGATTCAAGTT

>10954_10954_2_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000437989_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=395AA_BP=238
MILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLAN
EVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSF
LDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQEDYDRL
RPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLEC

--------------------------------------------------------------
>10954_10954_3_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000562489_RAC2_chr22_37628958_ENST00000249071_length(transcript)=1510nt_BP=257nt
GACTTCAGGTGAAGGACAGGCAGCAGGAGCAGATGAGATTTAGAATACCAAGACTGTGTGTACACGCAGATGTCAGTGGCAGAGAATGAA
GATCAGCTTCGTGCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGCTGTAGAAGGGCACATAATTCACTGGATT
GAAAGCAAAGCCTCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCATGACCAGTTCTGGAGCTACTGGAATAGGTTTGACAACTAT
TCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCTC
TCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAA
GTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAAG
GAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTC
ACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAGC
CTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCCCCACCCAAAGCCTGATGGCACCCCGGCTGGC
CATGCTGTCCCCTCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCAG
GAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGGGCCAGAGGGGAGCCCCAGGACCCATTAAGCC
ACCCCCGTGTTCCTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTCT
GGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCTTACTCCCTCCTGAGGCCAGCTGCTCTAATAT
CGATGGTCCTGCTTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTGG
AACAACATAAAACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAACCAGCCCCTGCCATTTC
TTAAGACTTTCTGCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTG

>10954_10954_3_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000562489_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=219AA_BP=62
MSVAENEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQED
YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVK

--------------------------------------------------------------
>10954_10954_4_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000562877_RAC2_chr22_37628958_ENST00000249071_length(transcript)=1887nt_BP=634nt
AGCTTTCTGTTTAGTTGTGTCAATCGCAGGCCACTCTGCTGAGCATCTTCTCCCAGGAGTACCAGAAACACATTAAAAGAACACATGCCA
AACATCATACTTCGGAAGCAATTGAAAGTTATTACCAGAGGTACCTGAATGGAGTGGTGAAAAATGGAGCTGCCCCAGTGCTCCTGGACC
TGGCCAATGAGGTGGACTATGCGCCCTCATTAATGGCTCGGCTTATACTGGAGAGGTTTCTACAGGAACACGAGGAAACTCCACCCTCCA
AGTCTATTATAAATAGTATGCTACGGGACCCTTCTCAGATTCCAGATGGAGTTCTAGCAAATCAGGTCTATCAGTGCATTGTGAACGACT
GCTGTTACGGACCACTAGTGGACTGCATCAAGCATGCCATTGGTCATGAGCATGAGGTCCTGCTGAGAGACTTGCTTCTAGAGAAAAACC
TGTCCTTCCTAGATGAAGATCAGCTTCGTGCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGCTGTAGAAGGGC
ACATAATTCACTGGATTGAAAGCAAAGCCTCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCATGACCAGTTCTGGAGCTACTGGA
ATAGGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACG
ACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCG
CCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACA
CCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACC
TGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGC
AGAAGCGCGCCTGCAGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCCCCACCCAAAGCCTG
ATGGCACCCCGGCTGGCCATGCTGTCCCCTCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGG
AGGCCTCCTGAGGCCAGGAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGGGCCAGAGGGGAGCC
CCAGGACCCATTAAGCCACCCCCGTGTTCCTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCC
ACGCCTGACTCCCCTCTGGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCTTACTCCCTCCTGAG
GCCAGCTGCTCTAATATCGATGGTCCTGCTTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCT
CAGTTCTCCTCTTTTGGAACAACATAAAACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAA
CCAGCCCCTGCCATTTCTTAAGACTTTCTGCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTT

>10954_10954_4_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000562877_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=363AA_BP=206
MCQSQATLLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLANEVDYAPSLMARLILERFLQEHEETPPSKSIIN
SMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHW
IESKASFGDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFP
EVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRAC

--------------------------------------------------------------
>10954_10954_5_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000566621_RAC2_chr22_37628958_ENST00000249071_length(transcript)=2219nt_BP=966nt
AAGCCAAGCTAGGGCACTCTGGTGTACAGCCAGTCCCCGCCGCGGAGGTGCCGGTGGAGCCTGGGACCGGGCGAGTCTCCGCCCCGCTTT
TGCAGCTAGGGGTGTGTTTCAGGGGGGATTGGGGCAAGCCAAGCAGGCGAGGACCCGGGCCTGTGCCGCTTTGCCTACCCCTCATCCCTC
GGCACCAAGGCTACTTGAGCCCCAGGGTGTTTTTTCCTTGTTCCCGCCACCTCCTGGTCCCTGGCCCAACATGATACTGACCAAAGCTCA
GTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCCTGAGGAAGCTGAAGCAGAGGTTTCCCAGTCAATCGCA
GGCCACTCTGCTGAGCATCTTCTCCCAGGAGTACCAGAAACACATTAAAAGAACACATGCCAAACATCATACTTCGGAAGCAATTGAAAG
TTATTACCAGAGGTACCTGAATGGAGTGGTGAAAAATGGAGCTGCCCCAGTGCTCCTGGACCTGGCCAATGAGGTGGACTATGCGCCCTC
ATTAATGGCTCGGCTTATACTGGAGAGGTTTCTACAGGAACACGAGGAAACTCCACCCTCCAAGTCTATTATAAATAGTATGCTACGGGA
CCCTTCTCAGATTCCAGATGGAGTTCTAGCAAATCAGGTCTATCAGTGCATTGTGAACGACTGCTGTTACGGACCACTAGTGGACTGCAT
CAAGCATGCCATTGGTCATGAGCATGAGGTCCTGCTGAGAGACTTGCTTCTAGAGAAAAACCTGTCCTTCCTAGATGAAGATCAGCTTCG
TGCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGCTGTAGAAGGGCACATAATTCACTGGATTGAAAGCAAAGC
CTCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCATGACCAGTTCTGGAGCTACTGGAATAGGTTTGACAACTATTCAGCCAATGT
GATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACA
GACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCA
CTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCT
GGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGG
CCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAGGG
GTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCC
CTCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCAGGAACGTGCAAA
TTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGGGCCAGAGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTT
CCTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTCTGGAAACTGCAG
GCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCTTACTCCCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTG
CTTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTGGAACAACATAAA
ACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTC
TGCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAAAT

>10954_10954_5_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000566621_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=439AA_BP=282
MGQAKQARTRACAALPTPHPSAPRLLEPQGVFSLFPPPPGPWPNMILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQ
EYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLANEVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPSQIPDGVL
ANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASFGDECSHH
AYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILV

--------------------------------------------------------------
>10954_10954_6_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000567389_RAC2_chr22_37628958_ENST00000249071_length(transcript)=1948nt_BP=695nt
AAGCTCAGCTTTCTGTTTAGTTGTGAGATTGCATACTCAAGAAGAGGAGGAACATAAAATACGTGATGTCTTCTCTTAAGTCAATCGCAG
GCCACTCTGCTGAGCATCTTCTCCCAGGAGTACCAGAAACACATTAAAAGAACACATGCCAAACATCATACTTCGGAAGCAATTGAAAGT
TATTACCAGAGGTACCTGAATGGAGTGGTGAAAAATGGAGCTGCCCCAGTGCTCCTGGACCTGGCCAATGAGGTGGACTATGCGCCCTCA
TTAATGGCTCGGCTTATACTGGAGAGGTTTCTACAGGAACACGAGGAAACTCCACCCTCCAAGTCTATTATAAATAGTATGCTACGGGAC
CCTTCTCAGATTCCAGATGGAGTTCTAGCAAATCAGGTCTATCAGTGCATTGTGAACGACTGCTGTTACGGACCACTAGTGGACTGCATC
AAGCATGCCATTGGTCATGAGCATGAGGTCCTGCTGAGAGACTTGCTTCTAGAGAAAAACCTGTCCTTCCTAGATGAAGATCAGCTTCGT
GCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGCTGTAGAAGGGCACATAATTCACTGGATTGAAAGCAAAGCC
TCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCATGACCAGTTCTGGAGCTACTGGAATAGGTTTGACAACTATTCAGCCAATGTG
ATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAG
ACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCAC
TGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTG
GCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGC
CTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAGGGG
TTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCAGGATCCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCC
TCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCAGGAACGTGCAAAT
TTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCCTTCCTGAGGGCCAGAGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTTC
CTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTACCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTCTGGAAACTGCAGG
CCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGATGGGGCTCTTACTCCCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTGC
TTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTCTCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTGGAACAACATAAAA
CAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCAGCCAATGGAAAATCTGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTCT
GCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGAGAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAAATA

>10954_10954_6_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000567389_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=356AA_BP=199
MLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLANEVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPS
QIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSFLDEDQLRAKGYDKTPDFILQVPVAVEGHIIHWIESKASF
GDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCP

--------------------------------------------------------------
>10954_10954_7_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000569302_RAC2_chr22_37628958_ENST00000249071_length(transcript)=2000nt_BP=747nt
TCCCTGGCCCAACATGATACTGACCAAAGCTCAGTACGACGAGATAGCCCAGTGCCTAGTGTCTGTGCCGCCTACCAGGCAGAGCCTGAG
GAAGCTGAAGCAGAGGTTTCCCAGTCAATCGCAGGCCACTCTGCTGAGCATCTTCTCCCAGGAGTACCAGAAACACATTAAAAGAACACA
TGCCAAACATCATACTTCGGAAGCAATTGAAAGTTATTACCAGAGGTACCTGAATGGAGTGGTGAAAAATGGAGCTGCCCCAGTGCTCCT
GGACCTGGCCAATGAGGTGGACTATGCGCCCTCATTAATGGCTCGGCTTATACTGGAGAGGTTTCTACAGGAACACGAGGAAACTCCACC
CTCCAAGTCTATTATAAATAGTATGCTACGGGACCCTTCTCAGATTCCAGATGGAGTTCTAGCAAATCAGGTCTATCAGTGCATTGTGAA
CGACTGCTGTTACGGACCACTAGTGGACTGCATCAAGCATGCCATTGGTCATGAGCATGAGGTCCTGCTGAGAGACTTGCTTCTAGAGAA
AAACCTGTCCTTCCTAGATGAAGATCAGCTTCGTGCAAAGGGTTATGACAAAACACCAGACTTCATTTTACAAGTACCAGTTGTAATGCT
TTGTCCCTTAGCTGTAGAAGGGCACATAATTCACTGGATTGAAAGCAAAGCCTCATTTGGTGATGAATGTAGCCACCACGCCTACCTGCA
TGACCAGTTCTGGAGCTACTGGAATAGGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGA
CACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCC
AGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCT
GGACCTGCGGGACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAA
GGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCT
GTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCT
CCAGGATCCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCCTGTGGCGTTTCTTAGCAGATGGCTGCAGAGCTTC
GTTGATGGTCTTTTCTGTACTGGAGGCCTCCTGAGGCCAGGAACGTGCAAATTTGCAGGTGCTGCATCCCAAGCCCCTCATGCTCCTGCC
TTCCTGAGGGCCAGAGGGGAGCCCCAGGACCCATTAAGCCACCCCCGTGTTCCTGCCGTCAGTGCCAACTGCCGCATGTGGAAGCATCTA
CCCGTTCACTCCAGTCCCACCCCACGCCTGACTCCCCTCTGGAAACTGCAGGCCAGATGGTTGCTGCCACAACTTGTGTACCTTCAGGGA
TGGGGCTCTTACTCCCTCCTGAGGCCAGCTGCTCTAATATCGATGGTCCTGCTTGCCAGAGAGTTCCTCTACCCAGCAAAAATGAGTGTC
TCAGAAGTGTGCTCCTCTGGCCTCAGTTCTCCTCTTTTGGAACAACATAAAACAAATTTAATTTTCTACGCCTCTGGGGATATCTGCTCA
GCCAATGGAAAATCTGGGTTCAACCAGCCCCTGCCATTTCTTAAGACTTTCTGCTGCACTCACAGGATCCTGAGCTGCACTTACCTGTGA
GAGTCTTCAAACTTTTAAACCTTGCCAGTCAGGACTTTTGCTATTGCAAATAGAAAACCCAACTCAACCTGCTTAAGCAGAAAATAAATT

>10954_10954_7_C15orf41-RAC2_C15orf41_chr15_37002162_ENST00000569302_RAC2_chr22_37628958_ENST00000249071_length(amino acids)=401AA_BP=244
MILTKAQYDEIAQCLVSVPPTRQSLRKLKQRFPSQSQATLLSIFSQEYQKHIKRTHAKHHTSEAIESYYQRYLNGVVKNGAAPVLLDLAN
EVDYAPSLMARLILERFLQEHEETPPSKSIINSMLRDPSQIPDGVLANQVYQCIVNDCCYGPLVDCIKHAIGHEHEVLLRDLLLEKNLSF
LDEDQLRAKGYDKTPDFILQVPVVMLCPLAVEGHIIHWIESKASFGDECSHHAYLHDQFWSYWNRFDNYSANVMVDSKPVNLGLWDTAGQ
EDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for C15orf41-RAC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for C15orf41-RAC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for C15orf41-RAC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource