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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:C1RL-CHMP7 (FusionGDB2 ID:11441)

Fusion Gene Summary for C1RL-CHMP7

check button Fusion gene summary
Fusion gene informationFusion gene name: C1RL-CHMP7
Fusion gene ID: 11441
HgeneTgene
Gene symbol

C1RL

CHMP7

Gene ID

51279

91782

Gene namecomplement C1r subcomponent likecharged multivesicular body protein 7
SynonymsC1RL1|C1RLP|C1r-LP|CLSPa-
Cytomap

12p13.31

8p21.3

Type of geneprotein-codingprotein-coding
Descriptioncomplement C1r subcomponent-like proteinC1r-like proteinC1r-like serine protease analog proteincomplement C1r-like proteinasecomplement component 1, r subcomponent-likecharged multivesicular body protein 7CHMP family, member 7chromatin-modifying protein 7
Modification date2020031320200313
UniProtAcc

Q9NZP8

Q8WUX9

Ensembl transtripts involved in fusion geneENST00000266542, ENST00000544702, 
ENST00000545337, ENST00000504702, 
ENST00000545280, 		ENST00000520102, 
ENST00000313219, ENST00000397677, 
Fusion gene scores* DoF score5 X 5 X 3=754 X 3 X 3=36
# samples 54
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: C1RL [Title/Abstract] AND CHMP7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC1RL(7260847)-CHMP7(23112760), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across C1RL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHMP7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BR-7851-11AC1RLchr12

7260847

-CHMP7chr8

23112760

+


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Fusion Gene ORF analysis for C1RL-CHMP7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000266542ENST00000520102C1RLchr12

7260847

-CHMP7chr8

23112760

+
5CDS-intronENST00000544702ENST00000520102C1RLchr12

7260847

-CHMP7chr8

23112760

+
5CDS-intronENST00000545337ENST00000520102C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000266542ENST00000313219C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000266542ENST00000397677C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000544702ENST00000313219C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000544702ENST00000397677C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000545337ENST00000313219C1RLchr12

7260847

-CHMP7chr8

23112760

+
In-frameENST00000545337ENST00000397677C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-3CDSENST00000504702ENST00000313219C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-3CDSENST00000504702ENST00000397677C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-3CDSENST00000545280ENST00000313219C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-3CDSENST00000545280ENST00000397677C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-intronENST00000504702ENST00000520102C1RLchr12

7260847

-CHMP7chr8

23112760

+
intron-intronENST00000545280ENST00000520102C1RLchr12

7260847

-CHMP7chr8

23112760

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000266542C1RLchr127260847-ENST00000397677CHMP7chr823112760+2677393931283396
ENST00000266542C1RLchr127260847-ENST00000313219CHMP7chr823112760+2684393931283396
ENST00000544702C1RLchr127260847-ENST00000397677CHMP7chr823112760+2642358581248396
ENST00000544702C1RLchr127260847-ENST00000313219CHMP7chr823112760+2649358581248396
ENST00000545337C1RLchr127260847-ENST00000397677CHMP7chr823112760+2614330301220396
ENST00000545337C1RLchr127260847-ENST00000313219CHMP7chr823112760+2621330301220396

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000266542ENST00000397677C1RLchr127260847-CHMP7chr823112760+0.0040795730.9959204
ENST00000266542ENST00000313219C1RLchr127260847-CHMP7chr823112760+0.0041040340.995896
ENST00000544702ENST00000397677C1RLchr127260847-CHMP7chr823112760+0.0041943150.9958056
ENST00000544702ENST00000313219C1RLchr127260847-CHMP7chr823112760+0.0042226480.99577737
ENST00000545337ENST00000397677C1RLchr127260847-CHMP7chr823112760+0.0044313630.9955687
ENST00000545337ENST00000313219C1RLchr127260847-CHMP7chr823112760+0.0044657840.9955342

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Fusion Genomic Features for C1RL-CHMP7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
C1RLchr127260846-CHMP7chr823112759+0.151923940.8480761
C1RLchr127260846-CHMP7chr823112759+0.151923940.8480761

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for C1RL-CHMP7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:7260847/chr8:23112760)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
C1RL

Q9NZP8

CHMP7

Q8WUX9

FUNCTION: Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. {ECO:0000269|PubMed:15358180, ECO:0000269|PubMed:15385675, ECO:0000269|PubMed:15527420}.FUNCTION: ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). Plays a role in the endosomal sorting pathway (PubMed:16856878). {ECO:0000269|PubMed:16856878, ECO:0000269|PubMed:26040712}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHMP7chr12:7260847chr8:23112760ENST00000313219110243_312157454.0Coiled coilOntology_term=ECO:0000255
TgeneCHMP7chr12:7260847chr8:23112760ENST00000397677211243_312157454.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneC1RLchr12:7260847chr8:23112760ENST00000266542-26165_230100488.0DomainSushi
HgeneC1RLchr12:7260847chr8:23112760ENST00000266542-26245_484100488.0DomainPeptidase S1
HgeneC1RLchr12:7260847chr8:23112760ENST00000266542-2639_163100488.0DomainCUB


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Fusion Gene Sequence for C1RL-CHMP7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>11441_11441_1_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000266542_CHMP7_chr8_23112760_ENST00000313219_length(transcript)=2684nt_BP=393nt
ATTTCCAGGAACTTCCTCCTCCCCCACCGGCCTTCACCTTTTGTTCCCTATCCTGGGCCAGTTCTCTCGCAGGTCCCAGATGTCCAGTTC
CAGATGCCTGGACCCAGAGTGTGGGGGAAATATCTCTGGAGAAGCCCTCACTCCAAAGGCTGTCCAGGCGCAATGTGGTGGCTGCTTCTC
TGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTCCGTCCTCTTGGCCCAAGAGCTACCCCAGCAGCTGACATCCCCCGGGTACCCAGAG
CCGTATGGCAAAGGCCAAGAGAGCAGCACGGACATCAAGGCTCCAGAGGGCTTTGCTGTGAGGCTCGTCTTCCAGGACTTCGACCTGGAG
CCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGAAAAGGCTGAGGAGGTGTATCGTCTGTATCAGAACTCGCCCCTCTCCTCCCACCCC
GTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGCTAACTCCTGCCCAGATGAGAGGACCTTCTACTTGGTGTTGCTGCAGCTGCAGAAG
GAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGAGAAGATTGTGAAGTTTGCCCGAGGGCCACGTGCCAAGGTCTCTCCAGTCAATGAC
GTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGAACAGCTTCTCTCACGCAAAGTGGAGTCCTTATCCCAGGAAGCAGAGAGGTGTAAA
GAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAAGCAGCTGGCACTGAGGTCTCTCAAGGCCAAGCAACGGACAGAGAAGCGCATCGAG
GCCTTGCATGCCAAGCTGGACACTGTTCAAGGCATCCTGGACCGGATCTATGCCTCCCAGACAGATCAGATGGTTTTTAACGCCTACCAG
GCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGATGTCACAGTGGAGAAGGCAGAGAGCCTCGTGGATCAGATCCAAGAGCTCTGTGAC
ACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGGGGTAACAAATGGCTTAGATTTTGACAGTGAAGAACTGGAGAAGGAATTGGACATC
CTCCTTCAGGATACCACCAAAGAACCTTTGGATCTGCCTGACAACCCCCGCAATAGGCATTTTACCAACAGCGTGCCTAACCCTAGGATC
TCAGATGCTGAACTTGAAGCTGAACTTGAGAAACTGTCCTTATCAGAGGGAGGTTTGGTCCCAAGCAGTAAATCTCCAAAAAGGCAATTG
GAACCGACTCTAAAGCCATTGTAGGACCCTCAAGTGAAGGACCCTCATGTAAAAGAGAGACCAGGCTTGCTGGGTGTGTACATAGTTATT
TAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGGAGAAAGGAGAACCACTGATTTTATCTGGATGCTACTACTTACTACAGGACAGATA
GAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCCCAGCTGTATCATGGACCTGCCTTCTCATCTTTATAGTGCCACGATTTATACAGTC
CTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTCTTGCCATTGGCACACTTAGATTTGTCTTCACCCACCAGCTTCGTTCCAGCCCATG
AAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAATCAGTTCCCACTCCCCCCTGCGGTTTTTTAGAGGGGTTTATCCTGTCGCTAATGTC
AGTTAAATAGCTTATTCCTGTCCCACTTGATTTCACTGGTAAGAATGAGAATGAAATACTTAAAGGTTTTATTTGAGGGGACTTAGCTGC
CATTTTATGGAAAAACATGTAGTATAAAAGGTTTTTCTCCAGGGTCATTTGACAGAATTCTCCAGGTGTTCAGAGAAAGAGGTCGCCCCA
AGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGGTGTGGCCGGTGGGCGCTGCCTCTTCATCTGATGGAGCCAGGAGGTCCGCCGGTGG
GGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCTGGGAAGAGGCCCAGTCACTACAGGACCCTGAGATGTCCAGACCCCTTATGCAAAG
AGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTAACTTAAAAATACATATCTATCTTCCAGAACAAGCCACACAACAACACACCTCCCC
TCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGAATTTGGAAAGTGTTTCATTTTGTGGCCTACTGCTCGGGGCAGGGGGGCTGAGCCA
GGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGCCAGATCTGTGGGGAGCTGCCCAGGCCACCCGTGCACCTGTCCTGCTTCCTGCAGT
CCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGACTTGGGGTAGGGGGACAGACGGGAAAGGGTCTGAATGCTCTGGCAATGGCGAGAAG
AAGCGATCGCCACACTGCCACTCTGCTGCCCAGCCACCAGGATTTCTGCCTGGAGCCCTTTGCCCTGTCCCTGCTGCCTGAGGTGGCGTA
GAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGCACAAATCGTTGTTCAATGAATTTCTCTCCAACTCGACCTTGGTAAACGGAAATGT

>11441_11441_1_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000266542_CHMP7_chr8_23112760_ENST00000313219_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------
>11441_11441_2_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000266542_CHMP7_chr8_23112760_ENST00000397677_length(transcript)=2677nt_BP=393nt
ATTTCCAGGAACTTCCTCCTCCCCCACCGGCCTTCACCTTTTGTTCCCTATCCTGGGCCAGTTCTCTCGCAGGTCCCAGATGTCCAGTTC
CAGATGCCTGGACCCAGAGTGTGGGGGAAATATCTCTGGAGAAGCCCTCACTCCAAAGGCTGTCCAGGCGCAATGTGGTGGCTGCTTCTC
TGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTCCGTCCTCTTGGCCCAAGAGCTACCCCAGCAGCTGACATCCCCCGGGTACCCAGAG
CCGTATGGCAAAGGCCAAGAGAGCAGCACGGACATCAAGGCTCCAGAGGGCTTTGCTGTGAGGCTCGTCTTCCAGGACTTCGACCTGGAG
CCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGAAAAGGCTGAGGAGGTGTATCGTCTGTATCAGAACTCGCCCCTCTCCTCCCACCCC
GTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGCTAACTCCTGCCCAGATGAGAGGACCTTCTACTTGGTGTTGCTGCAGCTGCAGAAG
GAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGAGAAGATTGTGAAGTTTGCCCGAGGGCCACGTGCCAAGGTCTCTCCAGTCAATGAC
GTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGAACAGCTTCTCTCACGCAAAGTGGAGTCCTTATCCCAGGAAGCAGAGAGGTGTAAA
GAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAAGCAGCTGGCACTGAGGTCTCTCAAGGCCAAGCAACGGACAGAGAAGCGCATCGAG
GCCTTGCATGCCAAGCTGGACACTGTTCAAGGCATCCTGGACCGGATCTATGCCTCCCAGACAGATCAGATGGTTTTTAACGCCTACCAG
GCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGATGTCACAGTGGAGAAGGCAGAGAGCCTCGTGGATCAGATCCAAGAGCTCTGTGAC
ACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGGGGTAACAAATGGCTTAGATTTTGACAGTGAAGAACTGGAGAAGGAATTGGACATC
CTCCTTCAGGATACCACCAAAGAACCTTTGGATCTGCCTGACAACCCCCGCAATAGGCATTTTACCAACAGCGTGCCTAACCCTAGGATC
TCAGATGCTGAACTTGAAGCTGAACTTGAGAAACTGTCCTTATCAGAGGGAGGTTTGGTCCCAAGCAGTAAATCTCCAAAAAGGCAATTG
GAACCGACTCTAAAGCCATTGTAGGACCCTCAAGTGAAGGACCCTCATGTAAAAGAGAGACCAGGCTTGCTGGGTGTGTACATAGTTATT
TAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGGAGAAAGGAGAACCACTGATTTTATCTGGATGCTACTACTTACTACAGGACAGATA
GAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCCCAGCTGTATCATGGACCTGCCTTCTCATCTTTATAGTGCCACGATTTATACAGTC
CTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTCTTGCCATTGGCACACTTAGATTTGTCTTCACCCACCAGCTTCGTTCCAGCCCATG
AAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAATCAGTTCCCACTCCCCCCTGCGGTTTTTTAGAGGGGTTTATCCTGTCGCTAATGTC
AGTTAAATAGCTTATTCCTGTCCCACTTGATTTCACTGGTAAGAATGAGAATGAAATACTTAAAGGTTTTATTTGAGGGGACTTAGCTGC
CATTTTATGGAAAAACATGTAGTATAAAAGGTTTTTCTCCAGGGTCATTTGACAGAATTCTCCAGGTGTTCAGAGAAAGAGGTCGCCCCA
AGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGGTGTGGCCGGTGGGCGCTGCCTCTTCATCTGATGGAGCCAGGAGGTCCGCCGGTGG
GGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCTGGGAAGAGGCCCAGTCACTACAGGACCCTGAGATGTCCAGACCCCTTATGCAAAG
AGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTAACTTAAAAATACATATCTATCTTCCAGAACAAGCCACACAACAACACACCTCCCC
TCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGAATTTGGAAAGTGTTTCATTTTGTGGCCTACTGCTCGGGGCAGGGGGGCTGAGCCA
GGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGCCAGATCTGTGGGGAGCTGCCCAGGCCACCCGTGCACCTGTCCTGCTTCCTGCAGT
CCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGACTTGGGGTAGGGGGACAGACGGGAAAGGGTCTGAATGCTCTGGCAATGGCGAGAAG
AAGCGATCGCCACACTGCCACTCTGCTGCCCAGCCACCAGGATTTCTGCCTGGAGCCCTTTGCCCTGTCCCTGCTGCCTGAGGTGGCGTA
GAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGCACAAATCGTTGTTCAATGAATTTCTCTCCAACTCGACCTTGGTAAACGGAAATGT

>11441_11441_2_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000266542_CHMP7_chr8_23112760_ENST00000397677_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------
>11441_11441_3_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000544702_CHMP7_chr8_23112760_ENST00000313219_length(transcript)=2649nt_BP=358nt
ACCTTTTGTTCCCTATCCTGGGCCAGTTCTCTCGCAGGTCCCAGATGTCCAGTTCCAGATGCCTGGACCCAGAGTGTGGGGGAAATATCT
CTGGAGAAGCCCTCACTCCAAAGGCTGTCCAGGCGCAATGTGGTGGCTGCTTCTCTGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTC
CGTCCTCTTGGCCCAAGAGCTACCCCAGCAGCTGACATCCCCCGGGTACCCAGAGCCGTATGGCAAAGGCCAAGAGAGCAGCACGGACAT
CAAGGCTCCAGAGGGCTTTGCTGTGAGGCTCGTCTTCCAGGACTTCGACCTGGAGCCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGA
AAAGGCTGAGGAGGTGTATCGTCTGTATCAGAACTCGCCCCTCTCCTCCCACCCCGTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGC
TAACTCCTGCCCAGATGAGAGGACCTTCTACTTGGTGTTGCTGCAGCTGCAGAAGGAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGA
GAAGATTGTGAAGTTTGCCCGAGGGCCACGTGCCAAGGTCTCTCCAGTCAATGACGTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGA
ACAGCTTCTCTCACGCAAAGTGGAGTCCTTATCCCAGGAAGCAGAGAGGTGTAAAGAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAA
GCAGCTGGCACTGAGGTCTCTCAAGGCCAAGCAACGGACAGAGAAGCGCATCGAGGCCTTGCATGCCAAGCTGGACACTGTTCAAGGCAT
CCTGGACCGGATCTATGCCTCCCAGACAGATCAGATGGTTTTTAACGCCTACCAGGCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGA
TGTCACAGTGGAGAAGGCAGAGAGCCTCGTGGATCAGATCCAAGAGCTCTGTGACACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGG
GGTAACAAATGGCTTAGATTTTGACAGTGAAGAACTGGAGAAGGAATTGGACATCCTCCTTCAGGATACCACCAAAGAACCTTTGGATCT
GCCTGACAACCCCCGCAATAGGCATTTTACCAACAGCGTGCCTAACCCTAGGATCTCAGATGCTGAACTTGAAGCTGAACTTGAGAAACT
GTCCTTATCAGAGGGAGGTTTGGTCCCAAGCAGTAAATCTCCAAAAAGGCAATTGGAACCGACTCTAAAGCCATTGTAGGACCCTCAAGT
GAAGGACCCTCATGTAAAAGAGAGACCAGGCTTGCTGGGTGTGTACATAGTTATTTAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGG
AGAAAGGAGAACCACTGATTTTATCTGGATGCTACTACTTACTACAGGACAGATAGAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCC
CAGCTGTATCATGGACCTGCCTTCTCATCTTTATAGTGCCACGATTTATACAGTCCTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTC
TTGCCATTGGCACACTTAGATTTGTCTTCACCCACCAGCTTCGTTCCAGCCCATGAAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAAT
CAGTTCCCACTCCCCCCTGCGGTTTTTTAGAGGGGTTTATCCTGTCGCTAATGTCAGTTAAATAGCTTATTCCTGTCCCACTTGATTTCA
CTGGTAAGAATGAGAATGAAATACTTAAAGGTTTTATTTGAGGGGACTTAGCTGCCATTTTATGGAAAAACATGTAGTATAAAAGGTTTT
TCTCCAGGGTCATTTGACAGAATTCTCCAGGTGTTCAGAGAAAGAGGTCGCCCCAAGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGG
TGTGGCCGGTGGGCGCTGCCTCTTCATCTGATGGAGCCAGGAGGTCCGCCGGTGGGGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCT
GGGAAGAGGCCCAGTCACTACAGGACCCTGAGATGTCCAGACCCCTTATGCAAAGAGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTA
ACTTAAAAATACATATCTATCTTCCAGAACAAGCCACACAACAACACACCTCCCCTCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGA
ATTTGGAAAGTGTTTCATTTTGTGGCCTACTGCTCGGGGCAGGGGGGCTGAGCCAGGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGC
CAGATCTGTGGGGAGCTGCCCAGGCCACCCGTGCACCTGTCCTGCTTCCTGCAGTCCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGAC
TTGGGGTAGGGGGACAGACGGGAAAGGGTCTGAATGCTCTGGCAATGGCGAGAAGAAGCGATCGCCACACTGCCACTCTGCTGCCCAGCC
ACCAGGATTTCTGCCTGGAGCCCTTTGCCCTGTCCCTGCTGCCTGAGGTGGCGTAGAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGC
ACAAATCGTTGTTCAATGAATTTCTCTCCAACTCGACCTTGGTAAACGGAAATGTTGGGGGTGAAGAGAAACAATCACTATTTTTTTCTT

>11441_11441_3_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000544702_CHMP7_chr8_23112760_ENST00000313219_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------
>11441_11441_4_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000544702_CHMP7_chr8_23112760_ENST00000397677_length(transcript)=2642nt_BP=358nt
ACCTTTTGTTCCCTATCCTGGGCCAGTTCTCTCGCAGGTCCCAGATGTCCAGTTCCAGATGCCTGGACCCAGAGTGTGGGGGAAATATCT
CTGGAGAAGCCCTCACTCCAAAGGCTGTCCAGGCGCAATGTGGTGGCTGCTTCTCTGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTC
CGTCCTCTTGGCCCAAGAGCTACCCCAGCAGCTGACATCCCCCGGGTACCCAGAGCCGTATGGCAAAGGCCAAGAGAGCAGCACGGACAT
CAAGGCTCCAGAGGGCTTTGCTGTGAGGCTCGTCTTCCAGGACTTCGACCTGGAGCCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGA
AAAGGCTGAGGAGGTGTATCGTCTGTATCAGAACTCGCCCCTCTCCTCCCACCCCGTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGC
TAACTCCTGCCCAGATGAGAGGACCTTCTACTTGGTGTTGCTGCAGCTGCAGAAGGAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGA
GAAGATTGTGAAGTTTGCCCGAGGGCCACGTGCCAAGGTCTCTCCAGTCAATGACGTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGA
ACAGCTTCTCTCACGCAAAGTGGAGTCCTTATCCCAGGAAGCAGAGAGGTGTAAAGAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAA
GCAGCTGGCACTGAGGTCTCTCAAGGCCAAGCAACGGACAGAGAAGCGCATCGAGGCCTTGCATGCCAAGCTGGACACTGTTCAAGGCAT
CCTGGACCGGATCTATGCCTCCCAGACAGATCAGATGGTTTTTAACGCCTACCAGGCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGA
TGTCACAGTGGAGAAGGCAGAGAGCCTCGTGGATCAGATCCAAGAGCTCTGTGACACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGG
GGTAACAAATGGCTTAGATTTTGACAGTGAAGAACTGGAGAAGGAATTGGACATCCTCCTTCAGGATACCACCAAAGAACCTTTGGATCT
GCCTGACAACCCCCGCAATAGGCATTTTACCAACAGCGTGCCTAACCCTAGGATCTCAGATGCTGAACTTGAAGCTGAACTTGAGAAACT
GTCCTTATCAGAGGGAGGTTTGGTCCCAAGCAGTAAATCTCCAAAAAGGCAATTGGAACCGACTCTAAAGCCATTGTAGGACCCTCAAGT
GAAGGACCCTCATGTAAAAGAGAGACCAGGCTTGCTGGGTGTGTACATAGTTATTTAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGG
AGAAAGGAGAACCACTGATTTTATCTGGATGCTACTACTTACTACAGGACAGATAGAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCC
CAGCTGTATCATGGACCTGCCTTCTCATCTTTATAGTGCCACGATTTATACAGTCCTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTC
TTGCCATTGGCACACTTAGATTTGTCTTCACCCACCAGCTTCGTTCCAGCCCATGAAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAAT
CAGTTCCCACTCCCCCCTGCGGTTTTTTAGAGGGGTTTATCCTGTCGCTAATGTCAGTTAAATAGCTTATTCCTGTCCCACTTGATTTCA
CTGGTAAGAATGAGAATGAAATACTTAAAGGTTTTATTTGAGGGGACTTAGCTGCCATTTTATGGAAAAACATGTAGTATAAAAGGTTTT
TCTCCAGGGTCATTTGACAGAATTCTCCAGGTGTTCAGAGAAAGAGGTCGCCCCAAGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGG
TGTGGCCGGTGGGCGCTGCCTCTTCATCTGATGGAGCCAGGAGGTCCGCCGGTGGGGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCT
GGGAAGAGGCCCAGTCACTACAGGACCCTGAGATGTCCAGACCCCTTATGCAAAGAGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTA
ACTTAAAAATACATATCTATCTTCCAGAACAAGCCACACAACAACACACCTCCCCTCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGA
ATTTGGAAAGTGTTTCATTTTGTGGCCTACTGCTCGGGGCAGGGGGGCTGAGCCAGGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGC
CAGATCTGTGGGGAGCTGCCCAGGCCACCCGTGCACCTGTCCTGCTTCCTGCAGTCCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGAC
TTGGGGTAGGGGGACAGACGGGAAAGGGTCTGAATGCTCTGGCAATGGCGAGAAGAAGCGATCGCCACACTGCCACTCTGCTGCCCAGCC
ACCAGGATTTCTGCCTGGAGCCCTTTGCCCTGTCCCTGCTGCCTGAGGTGGCGTAGAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGC
ACAAATCGTTGTTCAATGAATTTCTCTCCAACTCGACCTTGGTAAACGGAAATGTTGGGGGTGAAGAGAAACAATCACTATTTTTTTCTT

>11441_11441_4_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000544702_CHMP7_chr8_23112760_ENST00000397677_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------
>11441_11441_5_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000545337_CHMP7_chr8_23112760_ENST00000313219_length(transcript)=2621nt_BP=330nt
CTCTCGCAGGTCCCAGATGTCCAGTTCCAGATGCCTGGACCCAGAGTGTGGGGGAAATATCTCTGGAGAAGCCCTCACTCCAAAGGCTGT
CCAGGCGCAATGTGGTGGCTGCTTCTCTGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTCCGTCCTCTTGGCCCAAGAGCTACCCCAG
CAGCTGACATCCCCCGGGTACCCAGAGCCGTATGGCAAAGGCCAAGAGAGCAGCACGGACATCAAGGCTCCAGAGGGCTTTGCTGTGAGG
CTCGTCTTCCAGGACTTCGACCTGGAGCCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGAAAAGGCTGAGGAGGTGTATCGTCTGTAT
CAGAACTCGCCCCTCTCCTCCCACCCCGTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGCTAACTCCTGCCCAGATGAGAGGACCTTC
TACTTGGTGTTGCTGCAGCTGCAGAAGGAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGAGAAGATTGTGAAGTTTGCCCGAGGGCCA
CGTGCCAAGGTCTCTCCAGTCAATGACGTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGAACAGCTTCTCTCACGCAAAGTGGAGTCC
TTATCCCAGGAAGCAGAGAGGTGTAAAGAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAAGCAGCTGGCACTGAGGTCTCTCAAGGCC
AAGCAACGGACAGAGAAGCGCATCGAGGCCTTGCATGCCAAGCTGGACACTGTTCAAGGCATCCTGGACCGGATCTATGCCTCCCAGACA
GATCAGATGGTTTTTAACGCCTACCAGGCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGATGTCACAGTGGAGAAGGCAGAGAGCCTC
GTGGATCAGATCCAAGAGCTCTGTGACACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGGGGTAACAAATGGCTTAGATTTTGACAGT
GAAGAACTGGAGAAGGAATTGGACATCCTCCTTCAGGATACCACCAAAGAACCTTTGGATCTGCCTGACAACCCCCGCAATAGGCATTTT
ACCAACAGCGTGCCTAACCCTAGGATCTCAGATGCTGAACTTGAAGCTGAACTTGAGAAACTGTCCTTATCAGAGGGAGGTTTGGTCCCA
AGCAGTAAATCTCCAAAAAGGCAATTGGAACCGACTCTAAAGCCATTGTAGGACCCTCAAGTGAAGGACCCTCATGTAAAAGAGAGACCA
GGCTTGCTGGGTGTGTACATAGTTATTTAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGGAGAAAGGAGAACCACTGATTTTATCTGG
ATGCTACTACTTACTACAGGACAGATAGAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCCCAGCTGTATCATGGACCTGCCTTCTCAT
CTTTATAGTGCCACGATTTATACAGTCCTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTCTTGCCATTGGCACACTTAGATTTGTCTT
CACCCACCAGCTTCGTTCCAGCCCATGAAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAATCAGTTCCCACTCCCCCCTGCGGTTTTTT
AGAGGGGTTTATCCTGTCGCTAATGTCAGTTAAATAGCTTATTCCTGTCCCACTTGATTTCACTGGTAAGAATGAGAATGAAATACTTAA
AGGTTTTATTTGAGGGGACTTAGCTGCCATTTTATGGAAAAACATGTAGTATAAAAGGTTTTTCTCCAGGGTCATTTGACAGAATTCTCC
AGGTGTTCAGAGAAAGAGGTCGCCCCAAGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGGTGTGGCCGGTGGGCGCTGCCTCTTCATC
TGATGGAGCCAGGAGGTCCGCCGGTGGGGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCTGGGAAGAGGCCCAGTCACTACAGGACCC
TGAGATGTCCAGACCCCTTATGCAAAGAGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTAACTTAAAAATACATATCTATCTTCCAGA
ACAAGCCACACAACAACACACCTCCCCTCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGAATTTGGAAAGTGTTTCATTTTGTGGCCT
ACTGCTCGGGGCAGGGGGGCTGAGCCAGGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGCCAGATCTGTGGGGAGCTGCCCAGGCCAC
CCGTGCACCTGTCCTGCTTCCTGCAGTCCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGACTTGGGGTAGGGGGACAGACGGGAAAGGG
TCTGAATGCTCTGGCAATGGCGAGAAGAAGCGATCGCCACACTGCCACTCTGCTGCCCAGCCACCAGGATTTCTGCCTGGAGCCCTTTGC
CCTGTCCCTGCTGCCTGAGGTGGCGTAGAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGCACAAATCGTTGTTCAATGAATTTCTCTC
CAACTCGACCTTGGTAAACGGAAATGTTGGGGGTGAAGAGAAACAATCACTATTTTTTTCTTTTTTATCTGGTAAATAATTAAAAGAAAA

>11441_11441_5_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000545337_CHMP7_chr8_23112760_ENST00000313219_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------
>11441_11441_6_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000545337_CHMP7_chr8_23112760_ENST00000397677_length(transcript)=2614nt_BP=330nt
CTCTCGCAGGTCCCAGATGTCCAGTTCCAGATGCCTGGACCCAGAGTGTGGGGGAAATATCTCTGGAGAAGCCCTCACTCCAAAGGCTGT
CCAGGCGCAATGTGGTGGCTGCTTCTCTGGGGAGTCCTCCAGGCTTGCCCAACCCGGGGCTCCGTCCTCTTGGCCCAAGAGCTACCCCAG
CAGCTGACATCCCCCGGGTACCCAGAGCCGTATGGCAAAGGCCAAGAGAGCAGCACGGACATCAAGGCTCCAGAGGGCTTTGCTGTGAGG
CTCGTCTTCCAGGACTTCGACCTGGAGCCGTCCCAGGACTGTGCAGGGGACTCTGTCACAGAAAAGGCTGAGGAGGTGTATCGTCTGTAT
CAGAACTCGCCCCTCTCCTCCCACCCCGTGGTGGCCCTGTCAGAGCTCAGCACCCTCTGTGCTAACTCCTGCCCAGATGAGAGGACCTTC
TACTTGGTGTTGCTGCAGCTGCAGAAGGAGAAGAGGGTCACAGTCCTCGAGCAGAACGGGGAGAAGATTGTGAAGTTTGCCCGAGGGCCA
CGTGCCAAGGTCTCTCCAGTCAATGACGTAGATGTTGGGGTGTACCAGCTGATGCAGAGTGAACAGCTTCTCTCACGCAAAGTGGAGTCC
TTATCCCAGGAAGCAGAGAGGTGTAAAGAAGAAGCCCGCCGGGCATGCCGAGCAGGAAAGAAGCAGCTGGCACTGAGGTCTCTCAAGGCC
AAGCAACGGACAGAGAAGCGCATCGAGGCCTTGCATGCCAAGCTGGACACTGTTCAAGGCATCCTGGACCGGATCTATGCCTCCCAGACA
GATCAGATGGTTTTTAACGCCTACCAGGCTGGGGTAGGAGCACTCAAACTCTCCATGAAGGATGTCACAGTGGAGAAGGCAGAGAGCCTC
GTGGATCAGATCCAAGAGCTCTGTGACACCCAGGATGAAGTTTCTCAGACTCTGGCTGGTGGGGTAACAAATGGCTTAGATTTTGACAGT
GAAGAACTGGAGAAGGAATTGGACATCCTCCTTCAGGATACCACCAAAGAACCTTTGGATCTGCCTGACAACCCCCGCAATAGGCATTTT
ACCAACAGCGTGCCTAACCCTAGGATCTCAGATGCTGAACTTGAAGCTGAACTTGAGAAACTGTCCTTATCAGAGGGAGGTTTGGTCCCA
AGCAGTAAATCTCCAAAAAGGCAATTGGAACCGACTCTAAAGCCATTGTAGGACCCTCAAGTGAAGGACCCTCATGTAAAAGAGAGACCA
GGCTTGCTGGGTGTGTACATAGTTATTTAAACAAGAAACTCTCAGAATGTGTTTGGAAGAGGAGAAAGGAGAACCACTGATTTTATCTGG
ATGCTACTACTTACTACAGGACAGATAGAATTTCTGGAAGCGATGCTCCAAAGGCTTGCTCCCAGCTGTATCATGGACCTGCCTTCTCAT
CTTTATAGTGCCACGATTTATACAGTCCTGTGTCTGACCTGTCATTTCATAGCCTGCAGTTCTTGCCATTGGCACACTTAGATTTGTCTT
CACCCACCAGCTTCGTTCCAGCCCATGAAGGGGAAAGATTTGCAGCTTTGCCAAATCTGAATCAGTTCCCACTCCCCCCTGCGGTTTTTT
AGAGGGGTTTATCCTGTCGCTAATGTCAGTTAAATAGCTTATTCCTGTCCCACTTGATTTCACTGGTAAGAATGAGAATGAAATACTTAA
AGGTTTTATTTGAGGGGACTTAGCTGCCATTTTATGGAAAAACATGTAGTATAAAAGGTTTTTCTCCAGGGTCATTTGACAGAATTCTCC
AGGTGTTCAGAGAAAGAGGTCGCCCCAAGTGGCCCAGAGTCGTGACAGTCCGGAGGGGCTGGTGTGGCCGGTGGGCGCTGCCTCTTCATC
TGATGGAGCCAGGAGGTCCGCCGGTGGGGGAAAGGCTTCTTCCGAGGCTTCTGCACTCGCCTGGGAAGAGGCCCAGTCACTACAGGACCC
TGAGATGTCCAGACCCCTTATGCAAAGAGGCAAAATTGTTGCCTTGGCCCCATCATGGAGTAACTTAAAAATACATATCTATCTTCCAGA
ACAAGCCACACAACAACACACCTCCCCTCCTTGAGCCTGGCACACAGCACCGGGCTCTCTGAATTTGGAAAGTGTTTCATTTTGTGGCCT
ACTGCTCGGGGCAGGGGGGCTGAGCCAGGATGTGCAATAGAAGCAGGGGTTGTCCCCTCTGCCAGATCTGTGGGGAGCTGCCCAGGCCAC
CCGTGCACCTGTCCTGCTTCCTGCAGTCCCCACTCCCTGCCTCCTTTGAGGGACTGGGGGACTTGGGGTAGGGGGACAGACGGGAAAGGG
TCTGAATGCTCTGGCAATGGCGAGAAGAAGCGATCGCCACACTGCCACTCTGCTGCCCAGCCACCAGGATTTCTGCCTGGAGCCCTTTGC
CCTGTCCCTGCTGCCTGAGGTGGCGTAGAGCAGAGGAGAAGAATTTGCTCCAGGCCAGGAGCACAAATCGTTGTTCAATGAATTTCTCTC
CAACTCGACCTTGGTAAACGGAAATGTTGGGGGTGAAGAGAAACAATCACTATTTTTTTCTTTTTTATCTGGTAAATAATTAAAAGAAAA

>11441_11441_6_C1RL-CHMP7_C1RL_chr12_7260847_ENST00000545337_CHMP7_chr8_23112760_ENST00000397677_length(amino acids)=396AA_BP=94
MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEP
SQDCAGDSVTEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDV
DVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQA
GVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRIS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for C1RL-CHMP7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for C1RL-CHMP7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for C1RL-CHMP7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource