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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACACA-CYB5A (FusionGDB2 ID:1147)

Fusion Gene Summary for ACACA-CYB5A

check button Fusion gene summary
Fusion gene informationFusion gene name: ACACA-CYB5A
Fusion gene ID: 1147
HgeneTgene
Gene symbol

ACACA

CYB5A

Gene ID

31

1528

Gene nameacetyl-CoA carboxylase alphacytochrome b5 type A
SynonymsACAC|ACACAD|ACC|ACC1|ACCACYB5|MCB5|METAG
Cytomap

17q12

18q22.3

Type of geneprotein-codingprotein-coding
Descriptionacetyl-CoA carboxylase 1ACC-alphaacetyl-Coenzyme A carboxylase alphacytochrome b5cytochrome b5 type A (microsomal)epididymis secretory sperm binding proteintype 1 cyt-b5
Modification date2020031320200313
UniProtAcc

Q13085

P00167

Ensembl transtripts involved in fusion geneENST00000353139, ENST00000394406, 
ENST00000416895, ENST00000588142, 
ENST00000335166, ENST00000360679, 
ENST00000361253, ENST00000589665, 
ENST00000299438, ENST00000579064, 
ENST00000340533, ENST00000397914, 
ENST00000494131, 
Fusion gene scores* DoF score44 X 35 X 17=2618012 X 9 X 7=756
# samples 5113
** MAII scorelog2(51/26180*10)=-5.68182403997375
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/756*10)=-2.53987461119262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACACA [Title/Abstract] AND CYB5A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACACA(35687112)-CYB5A(71930712), # samples:1
ACACA(35687113)-CYB5A(71930712), # samples:1
Anticipated loss of major functional domain due to fusion event.ACACA-CYB5A seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ACACA-CYB5A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ACACA-CYB5A seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ACACA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CYB5A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-8238-01AACACAchr17

35687113

-CYB5Achr18

71930712

-
ChimerDB4STADTCGA-HU-8238ACACAchr17

35687112

-CYB5Achr18

71930712

-


Top

Fusion Gene ORF analysis for ACACA-CYB5A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000353139ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000353139ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000394406ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000394406ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000416895ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000416895ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000588142ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-5UTRENST00000588142ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-intronENST00000353139ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-intronENST00000353139ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-intronENST00000394406ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-intronENST00000394406ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-intronENST00000416895ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-intronENST00000416895ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
5CDS-intronENST00000588142ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
5CDS-intronENST00000588142ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000353139ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
Frame-shiftENST00000416895ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000394406ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
In-frameENST00000588142ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000335166ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000360679ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000361253ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000340533ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000340533ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000397914ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000397914ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000494131ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-3CDSENST00000589665ENST00000494131ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-5UTRENST00000335166ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-5UTRENST00000335166ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-5UTRENST00000360679ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-5UTRENST00000360679ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-5UTRENST00000361253ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-5UTRENST00000361253ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-5UTRENST00000589665ENST00000299438ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-5UTRENST00000589665ENST00000299438ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-intronENST00000335166ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-intronENST00000335166ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-intronENST00000360679ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-intronENST00000360679ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-intronENST00000361253ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-intronENST00000361253ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-
intron-intronENST00000589665ENST00000579064ACACAchr17

35687113

-CYB5Achr18

71930712

-
intron-intronENST00000589665ENST00000579064ACACAchr17

35687112

-CYB5Achr18

71930712

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394406ACACAchr1735687112-ENST00000340533CYB5Achr1871930712-982418113442109
ENST00000394406ACACAchr1735687112-ENST00000494131CYB5Achr1871930712-1005418113442109
ENST00000394406ACACAchr1735687112-ENST00000397914CYB5Achr1871930712-810418113442109
ENST00000588142ACACAchr1735687112-ENST00000340533CYB5Achr1871930712-79122748919398
ENST00000588142ACACAchr1735687112-ENST00000494131CYB5Achr1871930712-814227025183
ENST00000588142ACACAchr1735687112-ENST00000397914CYB5Achr1871930712-61922745919388
ENST00000394406ACACAchr1735687113-ENST00000340533CYB5Achr1871930712-982418113442109
ENST00000394406ACACAchr1735687113-ENST00000494131CYB5Achr1871930712-1005418113442109
ENST00000394406ACACAchr1735687113-ENST00000397914CYB5Achr1871930712-810418113442109
ENST00000588142ACACAchr1735687113-ENST00000340533CYB5Achr1871930712-79122748919398
ENST00000588142ACACAchr1735687113-ENST00000494131CYB5Achr1871930712-814227025183
ENST00000588142ACACAchr1735687113-ENST00000397914CYB5Achr1871930712-61922745919388

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394406ENST00000340533ACACAchr1735687112-CYB5Achr1871930712-0.088529850.9114702
ENST00000394406ENST00000494131ACACAchr1735687112-CYB5Achr1871930712-0.112630550.88736945
ENST00000394406ENST00000397914ACACAchr1735687112-CYB5Achr1871930712-0.0615635330.9384364
ENST00000588142ENST00000340533ACACAchr1735687112-CYB5Achr1871930712-0.0732356160.9267644
ENST00000588142ENST00000494131ACACAchr1735687112-CYB5Achr1871930712-0.0704757050.9295243
ENST00000588142ENST00000397914ACACAchr1735687112-CYB5Achr1871930712-0.0372775160.9627225
ENST00000394406ENST00000340533ACACAchr1735687113-CYB5Achr1871930712-0.088529850.9114702
ENST00000394406ENST00000494131ACACAchr1735687113-CYB5Achr1871930712-0.112630550.88736945
ENST00000394406ENST00000397914ACACAchr1735687113-CYB5Achr1871930712-0.0615635330.9384364
ENST00000588142ENST00000340533ACACAchr1735687113-CYB5Achr1871930712-0.0732356160.9267644
ENST00000588142ENST00000494131ACACAchr1735687113-CYB5Achr1871930712-0.0704757050.9295243
ENST00000588142ENST00000397914ACACAchr1735687113-CYB5Achr1871930712-0.0372775160.9627225

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Fusion Genomic Features for ACACA-CYB5A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ACACA-CYB5A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:35687112/chr18:71930712)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ACACA

Q13085

CYB5A

P00167

FUNCTION: Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656, PubMed:20457939, PubMed:29899443). {ECO:0000269|PubMed:20457939, ECO:0000269|PubMed:20952656, ECO:0000269|PubMed:29899443}.FUNCTION: Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCYB5Achr17:35687112chr18:71930712ENST0000034053305109_13143135.0TransmembraneHelical
TgeneCYB5Achr17:35687112chr18:71930712ENST0000039791404109_13143125.0TransmembraneHelical
TgeneCYB5Achr17:35687112chr18:71930712ENST0000049413106109_13143125.66666666666667TransmembraneHelical
TgeneCYB5Achr17:35687113chr18:71930712ENST0000034053305109_13143135.0TransmembraneHelical
TgeneCYB5Achr17:35687113chr18:71930712ENST0000039791404109_13143125.0TransmembraneHelical
TgeneCYB5Achr17:35687113chr18:71930712ENST0000049413106109_13143125.66666666666667TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-155117_61802269.0DomainBiotin carboxylation
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-1551576_191402269.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-1551918_223402269.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-155275_46602269.0DomainATP-grasp
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-155745_81902269.0DomainBiotinyl-binding
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-356117_6181122384.0DomainBiotin carboxylation
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-3561576_19141122384.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-3561918_22341122384.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-356275_4661122384.0DomainATP-grasp
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-356745_8191122384.0DomainBiotinyl-binding
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-154117_61802289.0DomainBiotin carboxylation
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-1541576_191402289.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-1541918_223402289.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-154275_46602289.0DomainATP-grasp
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-154745_81902289.0DomainBiotinyl-binding
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-356117_618752347.0DomainBiotin carboxylation
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-3561576_1914752347.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-3561918_2234752347.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-356275_466752347.0DomainATP-grasp
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-356745_819752347.0DomainBiotinyl-binding
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-155117_61802269.0DomainBiotin carboxylation
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-1551576_191402269.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-1551918_223402269.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-155275_46602269.0DomainATP-grasp
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-155745_81902269.0DomainBiotinyl-binding
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-356117_6181122384.0DomainBiotin carboxylation
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-3561576_19141122384.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-3561918_22341122384.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-356275_4661122384.0DomainATP-grasp
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-356745_8191122384.0DomainBiotinyl-binding
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-154117_61802289.0DomainBiotin carboxylation
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-1541576_191402289.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-1541918_223402289.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-154275_46602289.0DomainATP-grasp
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-154745_81902289.0DomainBiotinyl-binding
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-356117_618752347.0DomainBiotin carboxylation
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-3561576_1914752347.0DomainCoA carboxyltransferase N-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-3561918_2234752347.0DomainCoA carboxyltransferase C-terminal
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-356275_466752347.0DomainATP-grasp
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-356745_819752347.0DomainBiotinyl-binding
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-155315_32002269.0Nucleotide bindingATP
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-356315_3201122384.0Nucleotide bindingATP
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-154315_32002289.0Nucleotide bindingATP
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-356315_320752347.0Nucleotide bindingATP
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-155315_32002269.0Nucleotide bindingATP
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-356315_3201122384.0Nucleotide bindingATP
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-154315_32002289.0Nucleotide bindingATP
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-356315_320752347.0Nucleotide bindingATP
HgeneACACAchr17:35687112chr18:71930712ENST00000335166-1551576_223402269.0RegionCarboxyltransferase
HgeneACACAchr17:35687112chr18:71930712ENST00000353139-3561576_22341122384.0RegionCarboxyltransferase
HgeneACACAchr17:35687112chr18:71930712ENST00000360679-1541576_223402289.0RegionCarboxyltransferase
HgeneACACAchr17:35687112chr18:71930712ENST00000394406-3561576_2234752347.0RegionCarboxyltransferase
HgeneACACAchr17:35687113chr18:71930712ENST00000335166-1551576_223402269.0RegionCarboxyltransferase
HgeneACACAchr17:35687113chr18:71930712ENST00000353139-3561576_22341122384.0RegionCarboxyltransferase
HgeneACACAchr17:35687113chr18:71930712ENST00000360679-1541576_223402289.0RegionCarboxyltransferase
HgeneACACAchr17:35687113chr18:71930712ENST00000394406-3561576_2234752347.0RegionCarboxyltransferase
TgeneCYB5Achr17:35687112chr18:71930712ENST00000340533059_8543135.0DomainCytochrome b5 heme-binding
TgeneCYB5Achr17:35687112chr18:71930712ENST00000397914049_8543125.0DomainCytochrome b5 heme-binding
TgeneCYB5Achr17:35687112chr18:71930712ENST00000494131069_8543125.66666666666667DomainCytochrome b5 heme-binding
TgeneCYB5Achr17:35687113chr18:71930712ENST00000340533059_8543135.0DomainCytochrome b5 heme-binding
TgeneCYB5Achr17:35687113chr18:71930712ENST00000397914049_8543125.0DomainCytochrome b5 heme-binding
TgeneCYB5Achr17:35687113chr18:71930712ENST00000494131069_8543125.66666666666667DomainCytochrome b5 heme-binding


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Fusion Gene Sequence for ACACA-CYB5A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1147_1147_1_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000340533_length(transcript)=982nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGATGACAGACCAAAGTTAAACAAGCCTCCGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGT
GATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGA
AGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATA
TCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGCCTTTTTATTCATC

>1147_1147_1_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000340533_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_2_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000397914_length(transcript)=810nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGC
CTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAA
GCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAAC

>1147_1147_2_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000397914_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_3_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000494131_length(transcript)=1005nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGATGACAGACCAAAGTTAAACAAGCCTCCGGAACCTTAAAGGCGGTGTTTCAAGGAAACTCTTATCACTACTATTGATTCTAG
TTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAAC
ACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCA
CTTGAAAACAATGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTT
TTCGAGTGTGCCTTTTTATTCATCTACTTTATTTTGATGTTTCCTTAATGTGTAATTTACTTATTATAAGCATGATCTTTTAAAAATATA

>1147_1147_3_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000394406_CYB5A_chr18_71930712_ENST00000494131_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_4_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000340533_length(transcript)=791nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGATG
ACAGACCAAAGTTAAACAAGCCTCCGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCA
TCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTT
TGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATATCTCTTTCTTT
TTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGCCTTTTTATTCATCTACTTTATTTT

>1147_1147_4_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000340533_length(amino acids)=98AA_BP=0
MYRRYIKATATAEMAGITQLVHQLELESIVVIRVSGGLFNFGLSSGWSSPMMNVLDISLASVECPTSSKFSVASPPACSLKTSSPPGCLC

--------------------------------------------------------------
>1147_1147_5_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000397914_length(transcript)=619nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGAAA
CTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATC
GCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAA

>1147_1147_5_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000397914_length(amino acids)=88AA_BP=0

--------------------------------------------------------------
>1147_1147_6_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000494131_length(transcript)=814nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGATG
ACAGACCAAAGTTAAACAAGCCTCCGGAACCTTAAAGGCGGTGTTTCAAGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGT
GGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGA
AGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAA
TGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGC
CTTTTTATTCATCTACTTTATTTTGATGTTTCCTTAATGTGTAATTTACTTATTATAAGCATGATCTTTTAAAAATATATTTGGCTTTTA

>1147_1147_6_ACACA-CYB5A_ACACA_chr17_35687112_ENST00000588142_CYB5A_chr18_71930712_ENST00000494131_length(amino acids)=83AA_BP=

--------------------------------------------------------------
>1147_1147_7_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000340533_length(transcript)=982nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGATGACAGACCAAAGTTAAACAAGCCTCCGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGT
GATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGA
AGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATA
TCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGCCTTTTTATTCATC

>1147_1147_7_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000340533_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_8_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000397914_length(transcript)=810nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGC
CTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAA
GCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAAC

>1147_1147_8_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000397914_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_9_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000494131_length(transcript)=1005nt_BP=418nt
CGGCCTGGTGCTGCACGCCTGTCAGCCATCGCCCGAGCCGCCGGCGTCTCCTCCCGCCCAGCAGTTCCTCCACGCAGGGGCTCCGGAATC
GCCCGACCGCACACGTTGCCACCCTGAGGTCTTTCTGGAAGTGGATATCTACTCAGACAGTAAGAATTATAAGAGCTGTAAGAGCTCATT
TTGGAGGAATAATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAG
ATAACTCAGAGGATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAG
ATACACTCTCTGATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACA
AGCTGGAGGTGACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCT
CCATCCAGATGACAGACCAAAGTTAAACAAGCCTCCGGAACCTTAAAGGCGGTGTTTCAAGGAAACTCTTATCACTACTATTGATTCTAG
TTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAAC
ACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCA
CTTGAAAACAATGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTT
TTCGAGTGTGCCTTTTTATTCATCTACTTTATTTTGATGTTTCCTTAATGTGTAATTTACTTATTATAAGCATGATCTTTTAAAAATATA

>1147_1147_9_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000394406_CYB5A_chr18_71930712_ENST00000494131_length(amino acids)=109AA_BP=
MRSFWKWISTQTVRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGI

--------------------------------------------------------------
>1147_1147_10_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000340533_length(transcript)=791nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGATG
ACAGACCAAAGTTAAACAAGCCTCCGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCA
TCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTT
TGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAATGATTTTAATATATCTCTTTCTTT
TTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGCCTTTTTATTCATCTACTTTATTTT

>1147_1147_10_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000340533_length(amino acids)=98AA_BP=0
MYRRYIKATATAEMAGITQLVHQLELESIVVIRVSGGLFNFGLSSGWSSPMMNVLDISLASVECPTSSKFSVASPPACSLKTSSPPGCLC

--------------------------------------------------------------
>1147_1147_11_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000397914_length(transcript)=619nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGAAA
CTCTTATCACTACTATTGATTCTAGTTCCAGTTGGTGGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATC
GCCTATACATGGCAGAGGACTGAACACCTCCTCAGAAGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAA

>1147_1147_11_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000397914_length(amino acids)=88AA_BP=0

--------------------------------------------------------------
>1147_1147_12_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000494131_length(transcript)=814nt_BP=227nt
ATGGATGAACCATCTCCCTTGGCCCAACCTCTGGAGCTGAACCAGCACTCTCGATTCATAATAGGTTCTGTGTCTGAAGATAACTCAGAG
GATGAGATCAGCAACCTGGTGAAGTTGGACCTACTGGAGGAGAAGGAGGGCTCCTTGTCACCTGCTTCTGTTGGCTCAGATACACTCTCT
GATTTGGGGATCTCTAGCCTACAGGATGGCTTGGCCTTGCACATAAGCATCCTGGTGGGGAAGAAGTTTTAAGGGAACAAGCTGGAGGTG
ACGCTACTGAGAACTTTGAGGATGTCGGGCACTCTACAGATGCCAGGGAAATGTCCAAAACATTCATCATTGGGGAGCTCCATCCAGATG
ACAGACCAAAGTTAAACAAGCCTCCGGAACCTTAAAGGCGGTGTTTCAAGGAAACTCTTATCACTACTATTGATTCTAGTTCCAGTTGGT
GGACCAACTGGGTGATCCCTGCCATCTCTGCAGTGGCCGTCGCCTTGATGTATCGCCTATACATGGCAGAGGACTGAACACCTCCTCAGA
AGTCAGCGCAGGAAGAGCCTGCTTTGGACACGGGAGAAAAGAAGCCATTGCTAACTACTTCAACTGACAGAAACCTTCACTTGAAAACAA
TGATTTTAATATATCTCTTTCTTTTTCTTCCGACATTAGAAACAAAACAAAAAGAACTGTCCTTTCTGCGCTCAAATTTTTCGAGTGTGC
CTTTTTATTCATCTACTTTATTTTGATGTTTCCTTAATGTGTAATTTACTTATTATAAGCATGATCTTTTAAAAATATATTTGGCTTTTA

>1147_1147_12_ACACA-CYB5A_ACACA_chr17_35687113_ENST00000588142_CYB5A_chr18_71930712_ENST00000494131_length(amino acids)=83AA_BP=

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Fusion Gene PPI Analysis for ACACA-CYB5A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACACA-CYB5A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACACA-CYB5A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource