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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:C2orf76-ACOXL (FusionGDB2 ID:11673)

Fusion Gene Summary for C2orf76-ACOXL

check button Fusion gene summary
Fusion gene informationFusion gene name: C2orf76-ACOXL
Fusion gene ID: 11673
HgeneTgene
Gene symbol

C2orf76

ACOXL

Gene ID

130355

55289

Gene namechromosome 2 open reading frame 76acyl-CoA oxidase like
SynonymsAIM29-
Cytomap

2q14.2

2q13

Type of geneprotein-codingprotein-coding
DescriptionUPF0538 protein C2orf76acyl-coenzyme A oxidase-like proteinacyl-CoA oxidase-like protein
Modification date2020031320200313
UniProtAcc.

Q9NUZ1

Ensembl transtripts involved in fusion geneENST00000334816, ENST00000409466, 
ENST00000409523, ENST00000409877, 
ENST00000498049, 		ENST00000496981, 
ENST00000340561, ENST00000389811, 
ENST00000439055, 
Fusion gene scores* DoF score3 X 2 X 3=182 X 2 X 2=8
# samples 33
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/8*10)=1.90689059560852
Context

PubMed: C2orf76 [Title/Abstract] AND ACOXL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC2orf76(120097403)-ACOXL(111542309), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across C2orf76 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACOXL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-85-7696-01AC2orf76chr2

120097403

-ACOXLchr2

111542309

+


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Fusion Gene ORF analysis for C2orf76-ACOXL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000334816ENST00000496981C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5CDS-intronENST00000409466ENST00000496981C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5CDS-intronENST00000409523ENST00000496981C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5CDS-intronENST00000409877ENST00000496981C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5UTR-3CDSENST00000498049ENST00000340561C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5UTR-3CDSENST00000498049ENST00000389811C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5UTR-3CDSENST00000498049ENST00000439055C2orf76chr2

120097403

-ACOXLchr2

111542309

+
5UTR-intronENST00000498049ENST00000496981C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409466ENST00000340561C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409466ENST00000389811C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409466ENST00000439055C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409523ENST00000340561C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409523ENST00000389811C2orf76chr2

120097403

-ACOXLchr2

111542309

+
Frame-shiftENST00000409523ENST00000439055C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000334816ENST00000340561C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000334816ENST00000389811C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000334816ENST00000439055C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000409877ENST00000340561C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000409877ENST00000389811C2orf76chr2

120097403

-ACOXLchr2

111542309

+
In-frameENST00000409877ENST00000439055C2orf76chr2

120097403

-ACOXLchr2

111542309

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000334816C2orf76chr2120097403-ENST00000389811ACOXLchr2111542309+25991842411752503
ENST00000334816C2orf76chr2120097403-ENST00000439055ACOXLchr2111542309+22581842411851536
ENST00000334816C2orf76chr2120097403-ENST00000340561ACOXLchr2111542309+2134184241948235
ENST00000409877C2orf76chr2120097403-ENST00000389811ACOXLchr2111542309+30896747312242503
ENST00000409877C2orf76chr2120097403-ENST00000439055ACOXLchr2111542309+27486747312341536
ENST00000409877C2orf76chr2120097403-ENST00000340561ACOXLchr2111542309+26246747311438235

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000334816ENST00000389811C2orf76chr2120097403-ACOXLchr2111542309+0.0018312770.9981687
ENST00000334816ENST00000439055C2orf76chr2120097403-ACOXLchr2111542309+0.0058747520.99412525
ENST00000334816ENST00000340561C2orf76chr2120097403-ACOXLchr2111542309+0.002936060.99706393
ENST00000409877ENST00000389811C2orf76chr2120097403-ACOXLchr2111542309+0.001172360.99882764
ENST00000409877ENST00000439055C2orf76chr2120097403-ACOXLchr2111542309+0.003330940.9966691
ENST00000409877ENST00000340561C2orf76chr2120097403-ACOXLchr2111542309+0.0024168110.99758315

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Fusion Genomic Features for C2orf76-ACOXL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
C2orf76chr2120097402-ACOXLchr2111542308+1.02E-050.99998987
C2orf76chr2120097402-ACOXLchr2111542308+1.02E-050.99998987

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for C2orf76-ACOXL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:120097403/chr2:111542309)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ACOXL

Q9NUZ1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneACOXLchr2:120097403chr2:111542309ENST00000340561111350_35525280.0Nucleotide bindingFAD
TgeneACOXLchr2:120097403chr2:111542309ENST00000389811119350_35525548.0Nucleotide bindingFAD
TgeneACOXLchr2:120097403chr2:111542309ENST00000439055118350_35525581.0Nucleotide bindingFAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for C2orf76-ACOXL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>11673_11673_1_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000340561_length(transcript)=2134nt_BP=184nt
GCAAACGCCGGGAGTAGCCGAAGGGGACGCCGGGAACAGGAATTTCTTCACATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATC
CGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAATTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAG
CAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAGAAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTG
CGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCCCTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCA
GAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACGCGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGC
CCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATATTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGC
CCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTCCTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCAC
AGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGATATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCT
GCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTATTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGC
ACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGAAGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGGTC
CAGAATCATCTCCCAGAACTGCTGTTCAGCTCCAGCTGGTCTTTATTGAGCCCCTCTTGTGGACCAGGCTAATTTCCTGAAAACTGGTTT
TTGCTAACGTTTCTTACGCTTGCTCGTGAAATCAGCCACTTAACTGTTCTGGGTTTTCCCGTGGCAGATCCCTATAGGCTTCTCACTGCA
CTATCCCAAACTTTTTATCTGAGAATGTTGTGTGGCAAGATGTCTGCAGAGTGCCGCTTAGGAGATGCTGGCCTGGCGTCCACGGGTCTG
CTGTGTATGTCTCTCCAGGCAGATGGCCTGTCTCTGCCTGGCAAGGACGATCTGGGGTGGAAAAACTCTGATCTGAAAGTGAAATCATTG
ACTCCGTTACCATGTTCTGAATTCCCAGATCTCCCTGATATGGAAAGTGAAAATTGGCTTCTATTACACAATGCATCAAAATTCTTTTGT
ATAGGACCAGACCACTGATATCAAGGGCAGTGCACTGACTTTCAGTTCCTCTGCATCCCTTGGTCATGTTCCCACCTTTCAATGGGAACA
GAGAATAAAAATTCCAGCTCTAGGGCCCAGCCTAGTGGCCACCTCTCACGGACAGGCACCCGGCTGCTCAGTGTTATCCAATTACTAGAG
GCCATTCCTAGCATTTCAACTTGGGGAATTAATTTACTATTACTTTATTTTTATCTTTAGAGACAGAGTCTTGCTCTGTCACCCAGACTA
GAGTGTAGTGGCATGATCATAGCTCACTGCAGCCTTGAACTCCTGAGCTCAGGCAATCCTCCTGCCACAGCCACCTGAGTAGCTGGAACT
ATAGGCATGTGCCATCATGCCCAACTAATTTTATTTTTATTTCAGTTGTAGAGATGGAGCCTTACCCTGTTGCCCAGGCTGGTCTCTGAC
TCCTGGTCTCTAGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTAGGATTATAGGTGTGAGCCAACATGCTGTCCCCATTATTGACTGTT
ACCCTAAAGTGTGTGTTGCCTTTCTAGTTTGAGTAGAAAGTCCAGCATTATCTTTTTGGATAATATCCAGGTTTTGCTGTTTCTTTCTTT
ATTTTTCATAATGAGAACATTTGCTCTCTTGCTGACATTGGAGGGCGTCTGTTTACCTCTCCTGTAGGCACACAAAATTCCCAACGTTTA

>11673_11673_1_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000340561_length(amino acids)=235AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK

--------------------------------------------------------------
>11673_11673_2_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000389811_length(transcript)=2599nt_BP=184nt
GCAAACGCCGGGAGTAGCCGAAGGGGACGCCGGGAACAGGAATTTCTTCACATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATC
CGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAATTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAG
CAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAGAAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTG
CGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCCCTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCA
GAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACGCGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGC
CCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATATTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGC
CCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTCCTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCAC
AGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGATATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCT
GCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTATTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGC
ACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGAAGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGCCG
GAGGCAGTTTGGGCCCAAAACCAAGGAAGAGGTGAAGATCATTGAGCACCAAACACAGACCCTGCGGCTGATGCCCCACCTGGCCACAGC
CTTGGCCCTGACCTTCGTCAGCAGGTATGCTGGGGCCCTCCTGGATGAGGATGTCTTCCAGGGAAAGGAGCTGGTCAACAGTCGCTCGCT
GCAGGCTCTGGTGGCGGGGCTGAAGGCCTACAGCACCTGGGAGAACATCCGCTGCCTGCAGGACTGCCGCGAGTGCACTGGAGGCATGGG
TTACATGATGGAAAATCGAATCTCAGGCTTAAAGTGTGACACAGATGTGTTTGCCACTTTTGAAGGTGACGATGTTGTTATGCTTCAGGT
TGTGGGGCGGGAACTGCTGGCCCAATACACCAAACAGTATGAAGAAAAACCACTCTTTGGCCTGCTCCAAAACTGGGCTGAATCTGTGGG
GGACAAGCTGAGAACCAGTTTCCTGGCATTTAACATGGACACAGTTGATGATCTCGCCTTTCTGTTGAAAGCAGTGAAATTTCGTGAAAG
GGTTCTTCAGCGGGGTTTGGTGGCCAGAATTTATTATAAGGTAAAGACCAAGAAGGAGGATTTTTTCCATGCCTGGAACTCGTGTCTGCA
CCACGTGGCTTCTCTGTCCCTGGCACACACTCACCGAGTTACCTTAGAGCAGTTCTCCCTAGCAGTGAAGAGCTGTCCTGACCAAGAGGA
CCAGACTTTGTTAATGAAGTTTTGTCTGTTGTATGGAACCAAGCTGGTGTTTCAGGAGCGGGCCTGGTATTTAGAACATAAATACTTGAC
TCCCATGGCCAGCACGAGGATCAGGAATCAGGAGAGATGCTGAAACACAAACAGGTATAAGACTCAGTCTCCACATGAAGGGAGCTCATA
TCCAAGGACACAAAACCACTTTAAAAACATAAATACTGGCCAGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTATGGGAGGCTGAGGC
GGGCAGATCTCCTGAGCTCAGGAGTTCGACACCATCTTGGGCAACATGGTGAAACCCTGTCTACTAAAATACAAAAAAATTAGCTGGGCG
TGGTGGCATGTGGCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCACGAGAATCGCTTGAGCCCTGGAGTTGGAGGTTGCAGTGAGCAGAG
ATTGCGCCACTGTACTCCAGTTTGGACTACAGAGTGAGACTCCATCTCAAAACAAAACAAAACAACAACAGCAAAAAACAACAAAACAAA
ACACAAATACTCTCACAGGGCATGGAGGTTTTCGAATGAACTTGGCCATAAGAATAAATTCAGAGTTGACAGAACAGACGTCTTAGGAAT
AAATGCCATTCTTATGCTAGACCTTGAAGAGTAGAAAATTAAGAGATGGTGGCCCAATTGAGAGGGGAAAATGCAGTTGAAACTTCAGAC
AGGGTTGATAAAGTGAGGACGATCATAGACATGGAGTACTTAGACATATTAATAAACAATAAAGACTTTACCTGTCTAATGGAAAACCTG
GAGAAGTCGTCAGGAACCAGACTACAGTGGACCCTGGAGAACCTTGAAGAACATTTTTCCTTTTCAGGAAAACGGAGGTTACAGAGAAAA

>11673_11673_2_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000389811_length(amino acids)=503AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK
SARFNAMLAALTPSRLAVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDVFQ
GKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMGYMMENRISGLKCDTDVFATFEGDDVVMLQVVGRELLAQYTKQYEEKPLFG
LLQNWAESVGDKLRTSFLAFNMDTVDDLAFLLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLSLAHTHRVTLEQFSL

--------------------------------------------------------------
>11673_11673_3_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000439055_length(transcript)=2258nt_BP=184nt
GCAAACGCCGGGAGTAGCCGAAGGGGACGCCGGGAACAGGAATTTCTTCACATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATC
CGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAATTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAG
CAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAGAAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTG
CGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCCCTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCA
GAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACGCGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGC
CCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATATTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGC
CCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTCCTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCAC
AGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGATATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCT
GCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTATTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGC
ACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGAAGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGCCG
GAGGCAGTTTGGGCCCAAAACCAAGGAAGAGGTGAAGATCATTGAGCACCAAACACAGACCCTGCGGCTGATGCCCCACCTGGCCACAGC
CTTGGCCCTGACCTTCGTCAGCAGGTATGCTGGGGCCCTCCTGGATGAGGATGTCTTCCAGGGAAAGGAGCTGGTCAACAGTCGCTCGCT
GCAGGCTCTGGTGGCGGGGCTGAAGGCCTACAGCACCTGGGAGAACATCCGCTGCCTGCAGGACTGCCGCGAGTGCACTGGAGGCATGGT
TGTGGGGCGGGAACTGCTGGCCCAATACACCAAACAGTATGAAGAAAAACCACTCTTTGGCCTGCTCCAAAACTGGGCTGAATCTGTGGG
GGACAAGCTGAGAACCAGTTTCCTGGCATTTAACATGGACACAGTTGATGATCTCGCCTTTCTGTTGAAAGCAGTGAAATTTCGTGAAAG
GGTTCTTCAGCGGGGTTTGGTGGCCAGAATTTATTATAAGGTAAAGACCAAGAAGGAGGATTTTTTCCATGCCTGGAACTCGTGTCTGCA
CCACGTGGCTTCTCTGTCCCTGGCACACACTCACCGAGTTACCTTAGAGCAGTTCTCCCTAGCAGTGAAGAGCTGTCCTGACCAAGAGGA
CCAGACTTTGTTAATGAAGTTTTGTCTGTTGTATGGAACCAAGCTGGTGTTTCAGGAGCGGGCCTGGTATTTAGAACATAAATACTTGAC
TCCCATGGCCAGCACGAGGATCAGGAATCAGTTGCTGGATTTGTGCGACTCGGTGAAGGATGATGCCCGGAGGGTGATCTCGACCTTTAA
CATTCCACACACCTACCTCCACGCACCAATCGCCGGAATCTCCAACCCGCGGGCCGCGTGGGCTTTCTACCCTGCACCGCTGCAGCCGCG
GCCACGGGAAGAGGCGCGCTCCCGGCGGCCCAAGCTGGGAGCCAAGCTCTAACGGGTGTGGCGGGAAGTGTGGTGGCCCGCCAGCAGCTG
CCACGACGCTCGCTCCACCGACGCCCAGAGCTGTGGCCGAGGCCGGGGGCTGGCACCCGCTGGGCCGCCACTCTCGGGGATTTTGGTGGC
AAAGCGGAGGTCCCGCCGAGGCTGGCGAGGTGCGCGGCTGGCTGCTAGGAAAGAGATCCAGACGGTCGCCTGGTGCGCTGGATCCCTGTG
CCCTTTCCCTGAAACCCAGCCTGGCCTGACTGCAACCTCTCCCAACTTCAGTGCCGGATCCCCTAGACAATCAGGGTGGGCTCCCCGCTG
CGAGCGCGCCCCACAGCCGGGTGCCGCCAAAGGTCTCCTGCTGTTAGCGGTGACTCACATTCCCAGTGATTTAGAAAAACTGTGGTGCCG

>11673_11673_3_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000334816_ACOXL_chr2_111542309_ENST00000439055_length(amino acids)=536AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK
SARFNAMLAALTPSRLAVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDVFQ
GKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMVVGRELLAQYTKQYEEKPLFGLLQNWAESVGDKLRTSFLAFNMDTVDDLAF
LLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLSLAHTHRVTLEQFSLAVKSCPDQEDQTLLMKFCLLYGTKLVFQER

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>11673_11673_4_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000340561_length(transcript)=2624nt_BP=674nt
ACGGAGACCGAAGAACGGAGGTCCTTATGTTTCTTTTCTTTCCTTAAATCTTGCCCGGCCTGAAGAGGCCGGAAGTTGCATCTCTGGACA
AGTAAACTCTGAGACCTGGGAATGGCGGGCGGGACCCGCTCCTCCCTTGGGGTCTAGAGGAGACCCCCGGAGATGGTCCCTGATGAGCAG
CGTGATGGTGGAAAGCTGGACTGGTCTCCCGAAAGGCGAAGCCGAGGCTTCTTCCTCTGAACTTTTGGCACGTTCTTTGACTTGCTTGTG
GCCGTAGTGTCAGGCCTGTATTGCACATTTATGTCTGTGGTGCATTTCTCCATCTGGGCCAGCTGAGGGGCCCACGGACATAGGGCACCC
ACAATAGGCGTGTGTCTGCTGTGTGTTTGTGTTCGGCCGTCCTGCTTCTCTGTTTCCACACGTACACATGCCCCTGTGTTACTTTGGTTC
ATCTTCTGTACTCTGTCAGTTTTCTGCTGGTCAGAACATCTGTGACTGTGACAGAGCTGTCCAGGATTGCAGTGGATAGGAATTTCTTCA
CATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATCCGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAA
TTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAGCAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAG
AAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTGCGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCC
CTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCAGAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACG
CGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGCCCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATA
TTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGCCCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTC
CTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCACAGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGA
TATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCTGCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTA
TTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGCACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGA
AGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGGTCCAGAATCATCTCCCAGAACTGCTGTTCAGCTCCAGCTGGTCTTTATTGAG
CCCCTCTTGTGGACCAGGCTAATTTCCTGAAAACTGGTTTTTGCTAACGTTTCTTACGCTTGCTCGTGAAATCAGCCACTTAACTGTTCT
GGGTTTTCCCGTGGCAGATCCCTATAGGCTTCTCACTGCACTATCCCAAACTTTTTATCTGAGAATGTTGTGTGGCAAGATGTCTGCAGA
GTGCCGCTTAGGAGATGCTGGCCTGGCGTCCACGGGTCTGCTGTGTATGTCTCTCCAGGCAGATGGCCTGTCTCTGCCTGGCAAGGACGA
TCTGGGGTGGAAAAACTCTGATCTGAAAGTGAAATCATTGACTCCGTTACCATGTTCTGAATTCCCAGATCTCCCTGATATGGAAAGTGA
AAATTGGCTTCTATTACACAATGCATCAAAATTCTTTTGTATAGGACCAGACCACTGATATCAAGGGCAGTGCACTGACTTTCAGTTCCT
CTGCATCCCTTGGTCATGTTCCCACCTTTCAATGGGAACAGAGAATAAAAATTCCAGCTCTAGGGCCCAGCCTAGTGGCCACCTCTCACG
GACAGGCACCCGGCTGCTCAGTGTTATCCAATTACTAGAGGCCATTCCTAGCATTTCAACTTGGGGAATTAATTTACTATTACTTTATTT
TTATCTTTAGAGACAGAGTCTTGCTCTGTCACCCAGACTAGAGTGTAGTGGCATGATCATAGCTCACTGCAGCCTTGAACTCCTGAGCTC
AGGCAATCCTCCTGCCACAGCCACCTGAGTAGCTGGAACTATAGGCATGTGCCATCATGCCCAACTAATTTTATTTTTATTTCAGTTGTA
GAGATGGAGCCTTACCCTGTTGCCCAGGCTGGTCTCTGACTCCTGGTCTCTAGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTAGGATT
ATAGGTGTGAGCCAACATGCTGTCCCCATTATTGACTGTTACCCTAAAGTGTGTGTTGCCTTTCTAGTTTGAGTAGAAAGTCCAGCATTA
TCTTTTTGGATAATATCCAGGTTTTGCTGTTTCTTTCTTTATTTTTCATAATGAGAACATTTGCTCTCTTGCTGACATTGGAGGGCGTCT
GTTTACCTCTCCTGTAGGCACACAAAATTCCCAACGTTTATTTGAAGAAAAAGACAATTATTTGAGTAATTTGAATAAATAAACATTTTA

>11673_11673_4_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000340561_length(amino acids)=235AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK

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>11673_11673_5_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000389811_length(transcript)=3089nt_BP=674nt
ACGGAGACCGAAGAACGGAGGTCCTTATGTTTCTTTTCTTTCCTTAAATCTTGCCCGGCCTGAAGAGGCCGGAAGTTGCATCTCTGGACA
AGTAAACTCTGAGACCTGGGAATGGCGGGCGGGACCCGCTCCTCCCTTGGGGTCTAGAGGAGACCCCCGGAGATGGTCCCTGATGAGCAG
CGTGATGGTGGAAAGCTGGACTGGTCTCCCGAAAGGCGAAGCCGAGGCTTCTTCCTCTGAACTTTTGGCACGTTCTTTGACTTGCTTGTG
GCCGTAGTGTCAGGCCTGTATTGCACATTTATGTCTGTGGTGCATTTCTCCATCTGGGCCAGCTGAGGGGCCCACGGACATAGGGCACCC
ACAATAGGCGTGTGTCTGCTGTGTGTTTGTGTTCGGCCGTCCTGCTTCTCTGTTTCCACACGTACACATGCCCCTGTGTTACTTTGGTTC
ATCTTCTGTACTCTGTCAGTTTTCTGCTGGTCAGAACATCTGTGACTGTGACAGAGCTGTCCAGGATTGCAGTGGATAGGAATTTCTTCA
CATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATCCGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAA
TTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAGCAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAG
AAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTGCGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCC
CTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCAGAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACG
CGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGCCCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATA
TTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGCCCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTC
CTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCACAGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGA
TATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCTGCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTA
TTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGCACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGA
AGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGCCGGAGGCAGTTTGGGCCCAAAACCAAGGAAGAGGTGAAGATCATTGAGCACC
AAACACAGACCCTGCGGCTGATGCCCCACCTGGCCACAGCCTTGGCCCTGACCTTCGTCAGCAGGTATGCTGGGGCCCTCCTGGATGAGG
ATGTCTTCCAGGGAAAGGAGCTGGTCAACAGTCGCTCGCTGCAGGCTCTGGTGGCGGGGCTGAAGGCCTACAGCACCTGGGAGAACATCC
GCTGCCTGCAGGACTGCCGCGAGTGCACTGGAGGCATGGGTTACATGATGGAAAATCGAATCTCAGGCTTAAAGTGTGACACAGATGTGT
TTGCCACTTTTGAAGGTGACGATGTTGTTATGCTTCAGGTTGTGGGGCGGGAACTGCTGGCCCAATACACCAAACAGTATGAAGAAAAAC
CACTCTTTGGCCTGCTCCAAAACTGGGCTGAATCTGTGGGGGACAAGCTGAGAACCAGTTTCCTGGCATTTAACATGGACACAGTTGATG
ATCTCGCCTTTCTGTTGAAAGCAGTGAAATTTCGTGAAAGGGTTCTTCAGCGGGGTTTGGTGGCCAGAATTTATTATAAGGTAAAGACCA
AGAAGGAGGATTTTTTCCATGCCTGGAACTCGTGTCTGCACCACGTGGCTTCTCTGTCCCTGGCACACACTCACCGAGTTACCTTAGAGC
AGTTCTCCCTAGCAGTGAAGAGCTGTCCTGACCAAGAGGACCAGACTTTGTTAATGAAGTTTTGTCTGTTGTATGGAACCAAGCTGGTGT
TTCAGGAGCGGGCCTGGTATTTAGAACATAAATACTTGACTCCCATGGCCAGCACGAGGATCAGGAATCAGGAGAGATGCTGAAACACAA
ACAGGTATAAGACTCAGTCTCCACATGAAGGGAGCTCATATCCAAGGACACAAAACCACTTTAAAAACATAAATACTGGCCAGGTGCAGT
GGCTCATGCCTGTAATCCCAGCACTATGGGAGGCTGAGGCGGGCAGATCTCCTGAGCTCAGGAGTTCGACACCATCTTGGGCAACATGGT
GAAACCCTGTCTACTAAAATACAAAAAAATTAGCTGGGCGTGGTGGCATGTGGCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCACGAGA
ATCGCTTGAGCCCTGGAGTTGGAGGTTGCAGTGAGCAGAGATTGCGCCACTGTACTCCAGTTTGGACTACAGAGTGAGACTCCATCTCAA
AACAAAACAAAACAACAACAGCAAAAAACAACAAAACAAAACACAAATACTCTCACAGGGCATGGAGGTTTTCGAATGAACTTGGCCATA
AGAATAAATTCAGAGTTGACAGAACAGACGTCTTAGGAATAAATGCCATTCTTATGCTAGACCTTGAAGAGTAGAAAATTAAGAGATGGT
GGCCCAATTGAGAGGGGAAAATGCAGTTGAAACTTCAGACAGGGTTGATAAAGTGAGGACGATCATAGACATGGAGTACTTAGACATATT
AATAAACAATAAAGACTTTACCTGTCTAATGGAAAACCTGGAGAAGTCGTCAGGAACCAGACTACAGTGGACCCTGGAGAACCTTGAAGA
ACATTTTTCCTTTTCAGGAAAACGGAGGTTACAGAGAAAAGTATATGTAATGATGCTACAGTAATGTATTTCTGTATAACAAATGACTCC

>11673_11673_5_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000389811_length(amino acids)=503AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK
SARFNAMLAALTPSRLAVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDVFQ
GKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMGYMMENRISGLKCDTDVFATFEGDDVVMLQVVGRELLAQYTKQYEEKPLFG
LLQNWAESVGDKLRTSFLAFNMDTVDDLAFLLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLSLAHTHRVTLEQFSL

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>11673_11673_6_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000439055_length(transcript)=2748nt_BP=674nt
ACGGAGACCGAAGAACGGAGGTCCTTATGTTTCTTTTCTTTCCTTAAATCTTGCCCGGCCTGAAGAGGCCGGAAGTTGCATCTCTGGACA
AGTAAACTCTGAGACCTGGGAATGGCGGGCGGGACCCGCTCCTCCCTTGGGGTCTAGAGGAGACCCCCGGAGATGGTCCCTGATGAGCAG
CGTGATGGTGGAAAGCTGGACTGGTCTCCCGAAAGGCGAAGCCGAGGCTTCTTCCTCTGAACTTTTGGCACGTTCTTTGACTTGCTTGTG
GCCGTAGTGTCAGGCCTGTATTGCACATTTATGTCTGTGGTGCATTTCTCCATCTGGGCCAGCTGAGGGGCCCACGGACATAGGGCACCC
ACAATAGGCGTGTGTCTGCTGTGTGTTTGTGTTCGGCCGTCCTGCTTCTCTGTTTCCACACGTACACATGCCCCTGTGTTACTTTGGTTC
ATCTTCTGTACTCTGTCAGTTTTCTGCTGGTCAGAACATCTGTGACTGTGACAGAGCTGTCCAGGATTGCAGTGGATAGGAATTTCTTCA
CATGGCTCCTGGAGAAGTGACCATCACAGTTCGCCTCATCCGTTCCTTTGAACATCGCAATTTCAAACCTGTAGTGTATCACGGAGTGAA
TTTGGACCAAACTGTAAAGGAATTTATCGTATTTCTAAAGCAAGGCAGAGAAAACAAAGAATTTTGTCAGCCGAAGCCTTGTCATAGGAG
AAGTCCTCTCCATGGCGGACATGGCCACAGGAGTGAAGTGCGGAATAATTTATTGGCTATTTGGTGGTGCTATCAGGAATCTCGGAAGCC
CTGAACATGTTACTAAGTGGTTTCAGCCACTCCAGGAGCAGAAATACACTGGGATGTTTGCAATGACCGAGAGGGGCCATGGGAGCAACG
CGAGAGGGATCCAGACCGAAGCCACCTTTGACCTCTCTGCCCAGGAGTTTGTAATTGACACGCCGTGTGAAAATGCGGAGAAGATGTATA
TTGGAAATGCCATGTACGGGAATTATGCAGCTGTCTTTGCCCAGCTCATCATAGATGGAAGATCTCAAGGGCCCCACTGTTTCATCGTTC
CTGTCCGGGATGAAAACGGAAGCTTGTACCCAGGAGTCACAGCTATTGATATGATGTACAAGGAGGGTCTGCATGGTGTGGACAATGGGA
TATTAATATTTGACAAGGTTCGGATACCCAGGGAGAACCTGCTGGATAAGTTTGGTTCCGTGGCTCCAGATGGACAGTACCATTCGCCTA
TTAGGAACAAGAGTGCAAGATTCAATGCCATGCTGGCAGCACTGACCCCTTCGAGATTAGCTGTGGCTTTCCAAGCTATGGGTGCCATGA
AGCTTGGGTTGACGATAGCCATTCGCTATAGCCACAGCCGGAGGCAGTTTGGGCCCAAAACCAAGGAAGAGGTGAAGATCATTGAGCACC
AAACACAGACCCTGCGGCTGATGCCCCACCTGGCCACAGCCTTGGCCCTGACCTTCGTCAGCAGGTATGCTGGGGCCCTCCTGGATGAGG
ATGTCTTCCAGGGAAAGGAGCTGGTCAACAGTCGCTCGCTGCAGGCTCTGGTGGCGGGGCTGAAGGCCTACAGCACCTGGGAGAACATCC
GCTGCCTGCAGGACTGCCGCGAGTGCACTGGAGGCATGGTTGTGGGGCGGGAACTGCTGGCCCAATACACCAAACAGTATGAAGAAAAAC
CACTCTTTGGCCTGCTCCAAAACTGGGCTGAATCTGTGGGGGACAAGCTGAGAACCAGTTTCCTGGCATTTAACATGGACACAGTTGATG
ATCTCGCCTTTCTGTTGAAAGCAGTGAAATTTCGTGAAAGGGTTCTTCAGCGGGGTTTGGTGGCCAGAATTTATTATAAGGTAAAGACCA
AGAAGGAGGATTTTTTCCATGCCTGGAACTCGTGTCTGCACCACGTGGCTTCTCTGTCCCTGGCACACACTCACCGAGTTACCTTAGAGC
AGTTCTCCCTAGCAGTGAAGAGCTGTCCTGACCAAGAGGACCAGACTTTGTTAATGAAGTTTTGTCTGTTGTATGGAACCAAGCTGGTGT
TTCAGGAGCGGGCCTGGTATTTAGAACATAAATACTTGACTCCCATGGCCAGCACGAGGATCAGGAATCAGTTGCTGGATTTGTGCGACT
CGGTGAAGGATGATGCCCGGAGGGTGATCTCGACCTTTAACATTCCACACACCTACCTCCACGCACCAATCGCCGGAATCTCCAACCCGC
GGGCCGCGTGGGCTTTCTACCCTGCACCGCTGCAGCCGCGGCCACGGGAAGAGGCGCGCTCCCGGCGGCCCAAGCTGGGAGCCAAGCTCT
AACGGGTGTGGCGGGAAGTGTGGTGGCCCGCCAGCAGCTGCCACGACGCTCGCTCCACCGACGCCCAGAGCTGTGGCCGAGGCCGGGGGC
TGGCACCCGCTGGGCCGCCACTCTCGGGGATTTTGGTGGCAAAGCGGAGGTCCCGCCGAGGCTGGCGAGGTGCGCGGCTGGCTGCTAGGA
AAGAGATCCAGACGGTCGCCTGGTGCGCTGGATCCCTGTGCCCTTTCCCTGAAACCCAGCCTGGCCTGACTGCAACCTCTCCCAACTTCA
GTGCCGGATCCCCTAGACAATCAGGGTGGGCTCCCCGCTGCGAGCGCGCCCCACAGCCGGGTGCCGCCAAAGGTCTCCTGCTGTTAGCGG

>11673_11673_6_C2orf76-ACOXL_C2orf76_chr2_120097403_ENST00000409877_ACOXL_chr2_111542309_ENST00000439055_length(amino acids)=536AA_BP=
MADMATGVKCGIIYWLFGGAIRNLGSPEHVTKWFQPLQEQKYTGMFAMTERGHGSNARGIQTEATFDLSAQEFVIDTPCENAEKMYIGNA
MYGNYAAVFAQLIIDGRSQGPHCFIVPVRDENGSLYPGVTAIDMMYKEGLHGVDNGILIFDKVRIPRENLLDKFGSVAPDGQYHSPIRNK
SARFNAMLAALTPSRLAVAFQAMGAMKLGLTIAIRYSHSRRQFGPKTKEEVKIIEHQTQTLRLMPHLATALALTFVSRYAGALLDEDVFQ
GKELVNSRSLQALVAGLKAYSTWENIRCLQDCRECTGGMVVGRELLAQYTKQYEEKPLFGLLQNWAESVGDKLRTSFLAFNMDTVDDLAF
LLKAVKFRERVLQRGLVARIYYKVKTKKEDFFHAWNSCLHHVASLSLAHTHRVTLEQFSLAVKSCPDQEDQTLLMKFCLLYGTKLVFQER

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Fusion Gene PPI Analysis for C2orf76-ACOXL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for C2orf76-ACOXL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for C2orf76-ACOXL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource