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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:AASS-CADPS2 (FusionGDB2 ID:118) |
Fusion Gene Summary for AASS-CADPS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AASS-CADPS2 | Fusion gene ID: 118 | Hgene | Tgene | Gene symbol | AASS | CADPS2 | Gene ID | 10157 | 93664 |
| Gene name | aminoadipate-semialdehyde synthase | calcium dependent secretion activator 2 | |
| Synonyms | LKR/SDH|LKRSDH|LORSDH | CAPS2 | |
| Cytomap | 7q31.32 | 7q31.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alpha-aminoadipic semialdehyde synthase, mitochondrialalpha-aminoadipate semialdehyde synthaseaminoadipic semialdehyde synthaselysine-2-oxoglutarate reductaselysine-ketoglutarate reductase /saccharopine dehydrogenase | calcium-dependent secretion activator 2CAPS-2Ca++-dependent secretion activator 2Ca2+ dependent secretion activator 2Ca2+-dependent activator protein for secretion 2calcium-dependent activator protein for secretion 2 | |
| Modification date | 20200321 | 20200313 | |
| UniProtAcc | . | Q86UW7 | |
| Ensembl transtripts involved in fusion gene | ENST00000393376, ENST00000417368, ENST00000473553, | ENST00000476131, ENST00000313070, ENST00000334010, ENST00000412584, ENST00000449022, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 11 X 9 X 3=297 |
| # samples | 3 | 11 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(11/297*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AASS [Title/Abstract] AND CADPS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | AASS(121726066)-CADPS2(122377122), # samples:1 CADPS2(122303291)-AASS(121773795), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across AASS (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CADPS2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-94-7557-01A | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
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Fusion Gene ORF analysis for AASS-CADPS2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000393376 | ENST00000476131 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5CDS-intron | ENST00000417368 | ENST00000476131 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5UTR-3CDS | ENST00000473553 | ENST00000313070 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5UTR-3CDS | ENST00000473553 | ENST00000334010 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5UTR-3CDS | ENST00000473553 | ENST00000412584 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5UTR-3CDS | ENST00000473553 | ENST00000449022 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| 5UTR-intron | ENST00000473553 | ENST00000476131 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000393376 | ENST00000313070 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000393376 | ENST00000334010 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000393376 | ENST00000412584 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000393376 | ENST00000449022 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000417368 | ENST00000313070 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000417368 | ENST00000334010 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000417368 | ENST00000412584 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| In-frame | ENST00000417368 | ENST00000449022 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000393376 | AASS | chr7 | 121726066 | - | ENST00000313070 | CADPS2 | chr7 | 122377122 | - | 7447 | 2280 | 30 | 5708 | 1892 |
| ENST00000393376 | AASS | chr7 | 121726066 | - | ENST00000334010 | CADPS2 | chr7 | 122377122 | - | 7564 | 2280 | 30 | 5825 | 1931 |
| ENST00000393376 | AASS | chr7 | 121726066 | - | ENST00000412584 | CADPS2 | chr7 | 122377122 | - | 6128 | 2280 | 30 | 5708 | 1892 |
| ENST00000393376 | AASS | chr7 | 121726066 | - | ENST00000449022 | CADPS2 | chr7 | 122377122 | - | 5994 | 2280 | 30 | 5831 | 1933 |
| ENST00000417368 | AASS | chr7 | 121726066 | - | ENST00000313070 | CADPS2 | chr7 | 122377122 | - | 7486 | 2319 | 135 | 5747 | 1870 |
| ENST00000417368 | AASS | chr7 | 121726066 | - | ENST00000334010 | CADPS2 | chr7 | 122377122 | - | 7603 | 2319 | 135 | 5864 | 1909 |
| ENST00000417368 | AASS | chr7 | 121726066 | - | ENST00000412584 | CADPS2 | chr7 | 122377122 | - | 6167 | 2319 | 135 | 5747 | 1870 |
| ENST00000417368 | AASS | chr7 | 121726066 | - | ENST00000449022 | CADPS2 | chr7 | 122377122 | - | 6033 | 2319 | 135 | 5870 | 1911 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000393376 | ENST00000313070 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000124193 | 0.9998758 |
| ENST00000393376 | ENST00000334010 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000163068 | 0.9998369 |
| ENST00000393376 | ENST00000412584 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.00024926 | 0.9997508 |
| ENST00000393376 | ENST00000449022 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000225413 | 0.99977463 |
| ENST00000417368 | ENST00000313070 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000126337 | 0.99987364 |
| ENST00000417368 | ENST00000334010 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000165221 | 0.9998348 |
| ENST00000417368 | ENST00000412584 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000254365 | 0.99974567 |
| ENST00000417368 | ENST00000449022 | AASS | chr7 | 121726066 | - | CADPS2 | chr7 | 122377122 | - | 0.000229544 | 0.99977046 |
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Fusion Genomic Features for AASS-CADPS2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for AASS-CADPS2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:121726066/chr7:122377122) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | CADPS2 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 488_491 | 728 | 927.0 | Nucleotide binding | NADP |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 603_605 | 728 | 927.0 | Nucleotide binding | NADP |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 488_491 | 728 | 927.0 | Nucleotide binding | NADP |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 603_605 | 728 | 927.0 | Nucleotide binding | NADP |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 33_455 | 728 | 927.0 | Region | Note=Lysine-ketoglutarate reductase |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 577_578 | 728 | 927.0 | Region | Saccharopine binding |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 724_726 | 728 | 927.0 | Region | Saccharopine binding |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 33_455 | 728 | 927.0 | Region | Note=Lysine-ketoglutarate reductase |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 577_578 | 728 | 927.0 | Region | Saccharopine binding |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 724_726 | 728 | 927.0 | Region | Saccharopine binding |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000412584 | 0 | 28 | 350_464 | 113 | 1256.0 | Domain | C2 | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000412584 | 0 | 28 | 487_590 | 113 | 1256.0 | Domain | PH | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000412584 | 0 | 28 | 885_1056 | 113 | 1256.0 | Domain | MHD1 | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000449022 | 0 | 30 | 350_464 | 113 | 1297.0 | Domain | C2 | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000449022 | 0 | 30 | 487_590 | 113 | 1297.0 | Domain | PH | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000449022 | 0 | 30 | 885_1056 | 113 | 1297.0 | Domain | MHD1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000393376 | - | 18 | 23 | 477_926 | 728 | 927.0 | Region | Note=Saccharopine dehydrogenase |
| Hgene | AASS | chr7:121726066 | chr7:122377122 | ENST00000417368 | - | 19 | 24 | 477_926 | 728 | 927.0 | Region | Note=Saccharopine dehydrogenase |
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Fusion Gene Sequence for AASS-CADPS2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >118_118_1_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000313070_length(transcript)=7447nt_BP=2280nt CCTCAGATTTCTCAGGAGACCAGAACTGATCTGCCAGCCTTGCTGCCTTTTGTTGCTCTGCTCTTTACATTGTCTTTACAGTCACCAGGT GTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTC CGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAGCACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTG ATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTA ATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCC AATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTG GCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCT TTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGT TTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTA CCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCAT CATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGACAAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGAT ATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTC CTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTACCACACAAACTCGTGGCAATATGTGACATTTCAGCTGAC ACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGAC AGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCACAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATG CTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTG ATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGC ACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTATTAGAATATTTATCAAGAGATGGCAATATAGAAATAACA GTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAG AAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACA AACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAATTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATT GGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCA TATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCATTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTG ATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAATGTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCC ATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCAC ACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAGTTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAA ACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTATGAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTA CAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAACATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGC TTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATTTACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGA ATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTATGAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAA CACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCAGCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTG GCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGATATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTG AATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCGGAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCT GCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGACGTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAA GTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATGGAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAA GCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCTCGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACT GGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCAACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATG GTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTGCGAATGGATAAACCAGCACATATGAAGCATAGTGGATAT CTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTTGTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGC AGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGCTATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAG GGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTTGCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAA GCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAAACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCA GATGCTCAGCTTTATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTT TTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTG TTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTCTGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGT GCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTT TCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTT CCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAAAGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCA GAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATCAATTACACTAGACTCACAGAATATGCCAAAATAGAAGAG ACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAG CATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCAGAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACT GCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAACTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGT AATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTCCGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCA ATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAACAATGGCTCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTG CAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTA GAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTT TGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTCTGTGCCCTGGATGGAGGACAAGAGGTATGTAGAATTTTT CAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAAATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTG GAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCATCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATAT GTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTTGTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAAT GAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATGAAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTC CAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACCTACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACA CTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAGGCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGC ATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCTTTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTT ATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAATAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATG TAGAGTAAAAGGGGAAATGCCAAGATTTTGGGGTTTTTTTGTTTCCTTTTTTTGTTTGTTTGTTTGTTTGTTTTTTTGGAGAAGAGCATC CTCTTTTGTGTAGTTTGACCTAAAAATGAACCTTGGCTCTGCTTGTGATCAGAACATGAACTTTTTTTTTTAAAGAAGATTTGAGCATTT TTCTGTAATCACATCAAAATGATGTTTTCTGTGTAAAGCGAGATACATATTTCTCATAATGCAGCATTGTGAGAAGTCAGTTCGGACCAC TGCACCAACACTGTCGTATCCTTGTTAAAATGGTGTGTACCTTACAAATTATAATTTATGTGCCAGGTTCGTTTTGTACTTAATTTGCTA TTATTGTGATGTGTATAAAATCTTTAATCTTGGTTCTTAGTACTTTGAATTGGTCTACAGGTATATTCCTGGGATGAAAGGATTGCCAAA CCCAAATATAGACTAGATTATCCAATGGGTTTGTGTCTTTGTTCCATTCTCAACATTTCTTCTTTCAACTATAAGTAATCCCCAGGTGTG GGGTAGCAAGTGTGCTTCCGTCAAGATACCATATTCTCCTGCTCCAGTATAACAGCTTGCAGGCAATAAAAATCTATTTGCTCATAACTA CTTCTGTATTTATTAGACTTATATAGAGCAAATGCAGTAAAAGAGGTTTGCAGTGTTTCAAACATCCCAACTATCTGACTCTGTGTTTTT GTTTCTTGAGTTTTTTGTTTGTTTTGTTTGTAATATTTTGTTTTTAATCAAATGAGTAAAAGATAGTAACACTGACTGTTCTTTGTACCT AATAGGCACATACATTGTTAAAAGAATTACTATGACAGCATATTTCCATAGCAGAGGAAATATATATTTCATATATTATTAGTTAATATT AGTAATCAATGTTAACTAATAATTAGTAATGTTAGTAATATTAACTAGTAATTCACATTATTAGTGGTTCTCTCAAAATATTTTCTTGCT AGGGTTTGAGAGATAATTGTATTATGTTGCGTAAGTTCTCTATGAATTATTTTTGTGATATTTCCCAAAACATATTGGCAGATTGTGCTA CTGCATTTATTAATAAGTAATTTTTAAATGAAGGCAGTTAATGCAGAATAAGTGGAGGTATCCCTGCATTTATGAAAACGTTTATTCTGA AACTTTAGAAATGAAACAACTTGGACCTCCAGATTCGTTCTCCCATGGTGTAATAAGTGGTCGTTAGGTACCTAGACTAGCCTTAAAAAT CTATTTAATCTACAGTTACTATTTAGCATTGTTTTGGCTCATTTTCTGGGCCCTAGGGCTAAGATAACAAACAAGGAAATTTCTTCCTTC TTCCGGGATTAAAGACTAACTCTACCAACTCACTATCTTTGAAAGGCAGTTTGGGAATGTTCTCCCTCCTTTTCTTCTCTATTCACACAC CAAATACTATTTTCTCCAAACCCTCAAATGTCCAGTCATGCTATCCCAAACTCTCCAATGGCACCATCCCCAAGCTTGCTGTTCCACGAC >118_118_1_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000313070_length(amino acids)=1892AA_BP=750 MPALLPFVALLFTLSLQSPGVKMLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIH DKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAG MINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHEL KEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAG VEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMIL SDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIE QLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLD HMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLE GYPNRDSTKYAEIYGISSAHTLLRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDF REVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQL DNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENE IQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKEL GRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQ ELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLYADRFQ KHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHY SFAFCASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKC LEKAALINYTRLTEYAKIEETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSW DSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWP EQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEVCRIFQQYHSKIDDL IDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFD QWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEE -------------------------------------------------------------- >118_118_2_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000334010_length(transcript)=7564nt_BP=2280nt CCTCAGATTTCTCAGGAGACCAGAACTGATCTGCCAGCCTTGCTGCCTTTTGTTGCTCTGCTCTTTACATTGTCTTTACAGTCACCAGGT GTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTC CGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAGCACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTG ATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTA ATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCC AATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTG GCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCT TTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGT TTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTA CCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCAT CATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGACAAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGAT ATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTC CTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTACCACACAAACTCGTGGCAATATGTGACATTTCAGCTGAC ACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGAC AGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCACAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATG CTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTG ATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGC ACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTATTAGAATATTTATCAAGAGATGGCAATATAGAAATAACA GTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAG AAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACA AACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAATTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATT GGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCA TATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCATTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTG ATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAATGTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCC ATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCAC ACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAGTTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAA ACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTATGAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTA CAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAACATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGC TTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATTTACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGA ATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTATGAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAA CACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCAGCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTG GCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGATATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTG AATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCGGAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCT GCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGACGTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAA GTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATGGAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAA GCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCTCGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACT GGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCAACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATG GTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTGCGAATGGATAAACCAGCACATATGAAGCATAGTGGATAT CTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTTGTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGC AGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGCTATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAG GGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTTGCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAA GCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAAACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCA GATGCTCAGCTTTCTGAATTTACAGATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGAT CATGCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGC CAAGTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTCTGCTACCTTGCAGAACTGATGGAACAT TCAGAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGA ATTGGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTC AGATACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAAAGGGTTTTAATGAAAGATATTGCCACT CCCATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATCAATTACACTAGACTCACAGAATATGCC AAAATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAG CAGAATGAAGAGCATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCAGAGAAATTTTGGGCTTTATTTACAGTG GATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAACTGCTTAATAATTTCCTCCGAAATGAC ACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTCCGCTATGTGGATCTCATGGAGTCTTCC ATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAAGAATATCGCCAACAGTCTTCCCAATGTAGCTCTTCCA AAAGTTCCAAGTCTGCCTCTTAATCTTCCACAGATTCCTAACATTTCTACTGCTTCGTGGATGCCTTCTTTATATGAGTCCACCAATGGC TCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCAC CACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAA AAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAA CTCTGTGCCCTGGATGGAGGACAAGAGCAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAAATCATTTCACTG TTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCATCCATTCTGTCA TTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTTGTTCGGCAAAAC CAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATGAAAGTCATTTGC GTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACCTACAGGGACTTT CGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAGGCCACAGCCTCT GTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCTTTGCAGAAGGAA GGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAATAAAAATGCTTG TATTTCTTTAAAAAGTAAGCCTGAATGTAGAGTAAAAGGGGAAATGCCAAGATTTTGGGGTTTTTTTGTTTCCTTTTTTTGTTTGTTTGT TTGTTTGTTTTTTTGGAGAAGAGCATCCTCTTTTGTGTAGTTTGACCTAAAAATGAACCTTGGCTCTGCTTGTGATCAGAACATGAACTT TTTTTTTTAAAGAAGATTTGAGCATTTTTCTGTAATCACATCAAAATGATGTTTTCTGTGTAAAGCGAGATACATATTTCTCATAATGCA GCATTGTGAGAAGTCAGTTCGGACCACTGCACCAACACTGTCGTATCCTTGTTAAAATGGTGTGTACCTTACAAATTATAATTTATGTGC CAGGTTCGTTTTGTACTTAATTTGCTATTATTGTGATGTGTATAAAATCTTTAATCTTGGTTCTTAGTACTTTGAATTGGTCTACAGGTA TATTCCTGGGATGAAAGGATTGCCAAACCCAAATATAGACTAGATTATCCAATGGGTTTGTGTCTTTGTTCCATTCTCAACATTTCTTCT TTCAACTATAAGTAATCCCCAGGTGTGGGGTAGCAAGTGTGCTTCCGTCAAGATACCATATTCTCCTGCTCCAGTATAACAGCTTGCAGG CAATAAAAATCTATTTGCTCATAACTACTTCTGTATTTATTAGACTTATATAGAGCAAATGCAGTAAAAGAGGTTTGCAGTGTTTCAAAC ATCCCAACTATCTGACTCTGTGTTTTTGTTTCTTGAGTTTTTTGTTTGTTTTGTTTGTAATATTTTGTTTTTAATCAAATGAGTAAAAGA TAGTAACACTGACTGTTCTTTGTACCTAATAGGCACATACATTGTTAAAAGAATTACTATGACAGCATATTTCCATAGCAGAGGAAATAT ATATTTCATATATTATTAGTTAATATTAGTAATCAATGTTAACTAATAATTAGTAATGTTAGTAATATTAACTAGTAATTCACATTATTA GTGGTTCTCTCAAAATATTTTCTTGCTAGGGTTTGAGAGATAATTGTATTATGTTGCGTAAGTTCTCTATGAATTATTTTTGTGATATTT CCCAAAACATATTGGCAGATTGTGCTACTGCATTTATTAATAAGTAATTTTTAAATGAAGGCAGTTAATGCAGAATAAGTGGAGGTATCC CTGCATTTATGAAAACGTTTATTCTGAAACTTTAGAAATGAAACAACTTGGACCTCCAGATTCGTTCTCCCATGGTGTAATAAGTGGTCG TTAGGTACCTAGACTAGCCTTAAAAATCTATTTAATCTACAGTTACTATTTAGCATTGTTTTGGCTCATTTTCTGGGCCCTAGGGCTAAG ATAACAAACAAGGAAATTTCTTCCTTCTTCCGGGATTAAAGACTAACTCTACCAACTCACTATCTTTGAAAGGCAGTTTGGGAATGTTCT CCCTCCTTTTCTTCTCTATTCACACACCAAATACTATTTTCTCCAAACCCTCAAATGTCCAGTCATGCTATCCCAAACTCTCCAATGGCA CCATCCCCAAGCTTGCTGTTCCACGACACATTGCTCTGTACTTAGTAATTACCCACCCTTCTTTTCCTTTCAATAAAATGTCCATTTCCT >118_118_2_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000334010_length(amino acids)=1931AA_BP=750 MPALLPFVALLFTLSLQSPGVKMLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIH DKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAG MINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHEL KEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAG VEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMIL SDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIE QLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLD HMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLE GYPNRDSTKYAEIYGISSAHTLLRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDF REVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQL DNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENE IQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKEL GRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQ ELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLSEFTDA DRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPT LLHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKV VRKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQP QDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLP QIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRI PASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYV DVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTL -------------------------------------------------------------- >118_118_3_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000412584_length(transcript)=6128nt_BP=2280nt CCTCAGATTTCTCAGGAGACCAGAACTGATCTGCCAGCCTTGCTGCCTTTTGTTGCTCTGCTCTTTACATTGTCTTTACAGTCACCAGGT GTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTC CGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAGCACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTG ATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTA ATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCC AATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTG GCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCT TTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGT TTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTA CCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCAT CATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGACAAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGAT ATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTC CTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTACCACACAAACTCGTGGCAATATGTGACATTTCAGCTGAC ACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGAC AGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCACAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATG CTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTG ATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGC ACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTATTAGAATATTTATCAAGAGATGGCAATATAGAAATAACA GTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAG AAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACA AACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAATTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATT GGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCA TATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCATTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTG ATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAATGTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCC ATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCAC ACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAGTTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAA ACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTATGAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTA CAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAACATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGC TTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATTTACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGA ATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTATGAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAA CACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCAGCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTG GCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGATATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTG AATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCGGAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCT GCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGACGTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAA GTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATGGAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAA GCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCTCGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACT GGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCAACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATG GTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTGCGAATGGATAAACCAGCACATATGAAGCATAGTGGATAT CTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTTGTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGC AGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGCTATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAG GGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTTGCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAA GCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAAACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCA GATGCTCAGCTTTATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTT TTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTG TTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTCTGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGT GCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTT TCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTT CCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAAAGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCA GAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATCAATTACACTAGACTCACAGAATATGCCAAAATAGAAGAG ACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAG CATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCAGAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACT GCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAACTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGT AATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTCCGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCA ATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAACAATGGCTCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTG CAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTA GAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTT TGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTCTGTGCCCTGGATGGAGGACAAGAGTTTGGTAGTCAATGG CAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAAATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTG GAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCATCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATAT GTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTTGTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAAT GAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATGAAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTC CAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACCTACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACA CTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAGGCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGC ATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCTTTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTT ATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAATAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATG TAGAGTAAAAGGGGAAATGCCAAGATTTTGGGGTTTTTTTGTTTCCTTTTTTTGTTTGTTTGTTTGTTTGTTTTTTTGGAGAAGAGCATC CTCTTTTGTGTAGTTTGACCTAAAAATGAACCTTGGCTCTGCTTGTGATCAGAACATGAACTTTTTTTTTTAAAGAAGATTTGAGCATTT TTCTGTAATCACATCAAAATGATGTTTTCTGTGTAAAGCGAGATACATATTTCTCATAATGCAGCATTGTGAGAAGTCAGTTCGGACCAC >118_118_3_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000412584_length(amino acids)=1892AA_BP=750 MPALLPFVALLFTLSLQSPGVKMLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIH DKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAG MINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHEL KEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAG VEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMIL SDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIE QLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLD HMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLE GYPNRDSTKYAEIYGISSAHTLLRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDF REVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQL DNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENE IQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKEL GRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQ ELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLYADRFQ KHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHY SFAFCASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKC LEKAALINYTRLTEYAKIEETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSW DSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWP EQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDL IDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFD QWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQGITMKDSDEEE -------------------------------------------------------------- >118_118_4_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000449022_length(transcript)=5994nt_BP=2280nt CCTCAGATTTCTCAGGAGACCAGAACTGATCTGCCAGCCTTGCTGCCTTTTGTTGCTCTGCTCTTTACATTGTCTTTACAGTCACCAGGT GTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGCCTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTC CGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAGCACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTG ATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCTGGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTA ATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACTTATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCC AATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGATTATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTG GCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGAATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCT TTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTGCAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGT TTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGTAATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTA CCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGAGACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCAT CATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGACAAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGAT ATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAACACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTC CTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTACCACACAAACTCGTGGCAATATGTGACATTTCAGCTGAC ACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCCTTTTGCATGTATGATGCAGACCAGCATATTATTCATGAC AGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCACAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATG CTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTTGAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTG ATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTCCGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGC ACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTATTAGAATATTTATCAAGAGATGGCAATATAGAAATAACA GTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAATATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAG AAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCTTATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACA AACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAATTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATT GGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACAATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCA TATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCATTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTG ATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAATGTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCC ATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGTACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCAC ACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAGTTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAA ACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTATGAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTA CAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAACATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGC TTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATTTACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGA ATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTATGAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAA CACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCAGCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTG GCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGATATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTG AATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCGGAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCT GCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGACGTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAA GTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATGGAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAA GCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCTCGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACT GGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCAACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATG GTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTGCGAATGGATAAACCAGCACATATGAAGCATAGTGGATAT CTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTTGTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGC AGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGCTATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAG GGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTTGCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAA GCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAAACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCA GATGCTCAGCTTTCTGGTAAAGATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGATCAT GCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGCCAA GTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTCTGCTACCTTGCAGAACTGATGGAACATTCA GAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGAATT GGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTCAGA TACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAAAGGGTTTTAATGAAAGATATTGCCACTCCC ATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATCAATTACACTAGACTCACAGAATATGCCAAA ATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAGCAG AATGAAGAGCATCATGCAGAGGGAAGAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCAGAGAAATTTTGGGCTTTATTT ACAGTGGATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAACTGCTTAATAATTTCCTCCGA AATGACACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTCCGCTATGTGGATCTCATGGAG TCTTCCATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAAGAATATCGCCAACAGTCTTCCCAATGTAGCT CTTCCAAAAGTTCCAAGTCTGCCTCTTAATCTTCCACAGATTCCTAACATTTCTACTGCTTCGTGGATGCCTTCTTTATATGAGTCCACC AATGGCTCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTT GCCCACCACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAG CTACAAAAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGC ACCAAACTCTGTGCCCTGGATGGAGGACAAGAGCAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAAATCATT TCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCATCCATT CTGTCATTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTTGTTCGG CAAAACCAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATGAAAGTC ATTTGCGTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACCTACAGG GACTTTCGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAGGCCACA GCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCTTTGCAG AAGGAAGGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAATAAAAA >118_118_4_AASS-CADPS2_AASS_chr7_121726066_ENST00000393376_CADPS2_chr7_122377122_ENST00000449022_length(amino acids)=1933AA_BP=750 MPALLPFVALLFTLSLQSPGVKMLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIH DKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAG MINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHEL KEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAG VEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMIL SDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIE QLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLD HMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLE GYPNRDSTKYAEIYGISSAHTLLRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDF REVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQL DNADEQAAQIRRELDGRLQLADKMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENE IQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKEL GRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQ ELMQLEGYTVDYTDPHPGLQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLSGKDAD RFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTL LHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVV RKCLEKAALINYTRLTEYAKIEETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEA QPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLN LPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDL RIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAK YVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEG -------------------------------------------------------------- >118_118_5_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000313070_length(transcript)=7486nt_BP=2319nt AAACACCTCCTACTTCCCGGCCTTCCATCCCAGTTTCTTCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCGGAAGATTCGAGGCGGCGG GGGACAAGTCGGCGCCCCAGAGCGGACGAGTCACCAGGTGTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGC CTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTCCGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAG CACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCT GGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACT TATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGAT TATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGA ATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTG CAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGT AATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTACCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGA GACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGAC AAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAAC ACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTA CCACACAAACTCGTGGCAATATGTGACATTTCAGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCC TTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCA CAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTT GAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTC CGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGCACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTA TTAGAATATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAAT ATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAGAAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCT TATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAA TTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACA ATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCA TTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTGATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAAT GTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCCATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGT ACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAG TTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAAACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTAT GAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTACAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAAC ATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGCTTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATT TACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGAATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTAT GAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAACACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCA GCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTGGCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGAT ATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTGAATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCG GAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCTGCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGAC GTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAAGTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATG GAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAAGCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCT CGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACTGGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCA ACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATGGTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTG CGAATGGATAAACCAGCACATATGAAGCATAGTGGATATCTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTT GTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGCAGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGC TATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAGGGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTT GCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAAGCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAA ACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCAGATGCTCAGCTTTATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTT ATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTAT TCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTC TGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCT CATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCC CTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAA AGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATC AATTACACTAGACTCACAGAATATGCCAAAATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTG GCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAGCATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCA GAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAA CTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTC CGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAACAATGGCTCA GCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCAC TTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAG GCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTC TGTGCCCTGGATGGAGGACAAGAGGTATGTAGAATTTTTCAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAA ATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCA TCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTT GTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATG AAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACC TACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAG GCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCT TTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAA TAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATGTAGAGTAAAAGGGGAAATGCCAAGATTTTGGGGTTTTTTTGTTTCCTTTTT TTGTTTGTTTGTTTGTTTGTTTTTTTGGAGAAGAGCATCCTCTTTTGTGTAGTTTGACCTAAAAATGAACCTTGGCTCTGCTTGTGATCA GAACATGAACTTTTTTTTTTAAAGAAGATTTGAGCATTTTTCTGTAATCACATCAAAATGATGTTTTCTGTGTAAAGCGAGATACATATT TCTCATAATGCAGCATTGTGAGAAGTCAGTTCGGACCACTGCACCAACACTGTCGTATCCTTGTTAAAATGGTGTGTACCTTACAAATTA TAATTTATGTGCCAGGTTCGTTTTGTACTTAATTTGCTATTATTGTGATGTGTATAAAATCTTTAATCTTGGTTCTTAGTACTTTGAATT GGTCTACAGGTATATTCCTGGGATGAAAGGATTGCCAAACCCAAATATAGACTAGATTATCCAATGGGTTTGTGTCTTTGTTCCATTCTC AACATTTCTTCTTTCAACTATAAGTAATCCCCAGGTGTGGGGTAGCAAGTGTGCTTCCGTCAAGATACCATATTCTCCTGCTCCAGTATA ACAGCTTGCAGGCAATAAAAATCTATTTGCTCATAACTACTTCTGTATTTATTAGACTTATATAGAGCAAATGCAGTAAAAGAGGTTTGC AGTGTTTCAAACATCCCAACTATCTGACTCTGTGTTTTTGTTTCTTGAGTTTTTTGTTTGTTTTGTTTGTAATATTTTGTTTTTAATCAA ATGAGTAAAAGATAGTAACACTGACTGTTCTTTGTACCTAATAGGCACATACATTGTTAAAAGAATTACTATGACAGCATATTTCCATAG CAGAGGAAATATATATTTCATATATTATTAGTTAATATTAGTAATCAATGTTAACTAATAATTAGTAATGTTAGTAATATTAACTAGTAA TTCACATTATTAGTGGTTCTCTCAAAATATTTTCTTGCTAGGGTTTGAGAGATAATTGTATTATGTTGCGTAAGTTCTCTATGAATTATT TTTGTGATATTTCCCAAAACATATTGGCAGATTGTGCTACTGCATTTATTAATAAGTAATTTTTAAATGAAGGCAGTTAATGCAGAATAA GTGGAGGTATCCCTGCATTTATGAAAACGTTTATTCTGAAACTTTAGAAATGAAACAACTTGGACCTCCAGATTCGTTCTCCCATGGTGT AATAAGTGGTCGTTAGGTACCTAGACTAGCCTTAAAAATCTATTTAATCTACAGTTACTATTTAGCATTGTTTTGGCTCATTTTCTGGGC CCTAGGGCTAAGATAACAAACAAGGAAATTTCTTCCTTCTTCCGGGATTAAAGACTAACTCTACCAACTCACTATCTTTGAAAGGCAGTT TGGGAATGTTCTCCCTCCTTTTCTTCTCTATTCACACACCAAATACTATTTTCTCCAAACCCTCAAATGTCCAGTCATGCTATCCCAAAC TCTCCAATGGCACCATCCCCAAGCTTGCTGTTCCACGACACATTGCTCTGTACTTAGTAATTACCCACCCTTCTTTTCCTTTCAATAAAA >118_118_5_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000313070_length(amino acids)=1870AA_BP=728 MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLIL GVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHH LVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVIT SNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYI SYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL LRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLS KETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAD KMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQ GLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVV PKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGG CMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFR ILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSV EEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETM NQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNG KFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEA CVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEVCRIFQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEG VLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQL -------------------------------------------------------------- >118_118_6_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000334010_length(transcript)=7603nt_BP=2319nt AAACACCTCCTACTTCCCGGCCTTCCATCCCAGTTTCTTCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCGGAAGATTCGAGGCGGCGG GGGACAAGTCGGCGCCCCAGAGCGGACGAGTCACCAGGTGTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGC CTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTCCGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAG CACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCT GGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACT TATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGAT TATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGA ATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTG CAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGT AATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTACCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGA GACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGAC AAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAAC ACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTA CCACACAAACTCGTGGCAATATGTGACATTTCAGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCC TTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCA CAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTT GAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTC CGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGCACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTA TTAGAATATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAAT ATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAGAAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCT TATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAA TTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACA ATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCA TTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTGATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAAT GTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCCATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGT ACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAG TTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAAACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTAT GAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTACAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAAC ATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGCTTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATT TACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGAATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTAT GAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAACACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCA GCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTGGCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGAT ATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTGAATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCG GAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCTGCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGAC GTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAAGTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATG GAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAAGCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCT CGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACTGGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCA ACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATGGTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTG CGAATGGATAAACCAGCACATATGAAGCATAGTGGATATCTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTT GTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGCAGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGC TATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAGGGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTT GCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAAGCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAA ACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCAGATGCTCAGCTTTCTGAATTTACAGATGCAGATCGTTTTCAGAAACATGGT ATGGATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTG AATGATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGT CACAGACATCTCTGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCA TTCTGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAG AGACTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTT TCATTACTTGAAAGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAA GCTGCCTTGATCAATTACACTAGACTCACAGAATATGCCAAAATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAG ATTCTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAGCATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTG GCTGAACATGCAGAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTT CCTCTTTTCCAACTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTA CCCTTGGTTGTCCGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTC AAGAATATCGCCAACAGTCTTCCCAATGTAGCTCTTCCAAAAGTTCCAAGTCTGCCTCTTAATCTTCCACAGATTCCTAACATTTCTACT GCTTCGTGGATGCCTTCTTTATATGAGTCCACCAATGGCTCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAAATGTTT GTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAGGCCTGT GTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGCACTATG TTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTCTGTGCCCTGGATGGAGGACAAGAGCAACAGTACCATTCAAAAATAGAT GATCTGATCGACAACAGTGTAAAAGAAATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAGCTGTCA AGGTATGATGAAGGCACTTTCTTTTCATCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCAGGAATG GATCTGGCAGACACCTATATTATGTTTGTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAAAAGTTA TTTGATCAATGGTACAGCAGTTCCATGAAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAGCTGAAG ACGCTCATCAAGATTGTGAAGAAAACCTACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTATGATACT GTGCACAGACGTTTAACAGTAGAGGAGGCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGTGACGAA GAAGAAGAAGGCTGATATCACACAGCTTTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCCTTGTAA TTACATTCATTGTTTGTTTTGGCCAAATAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATGTAGAGTAAAAGGGGAAATGCCAAG ATTTTGGGGTTTTTTTGTTTCCTTTTTTTGTTTGTTTGTTTGTTTGTTTTTTTGGAGAAGAGCATCCTCTTTTGTGTAGTTTGACCTAAA AATGAACCTTGGCTCTGCTTGTGATCAGAACATGAACTTTTTTTTTTAAAGAAGATTTGAGCATTTTTCTGTAATCACATCAAAATGATG TTTTCTGTGTAAAGCGAGATACATATTTCTCATAATGCAGCATTGTGAGAAGTCAGTTCGGACCACTGCACCAACACTGTCGTATCCTTG TTAAAATGGTGTGTACCTTACAAATTATAATTTATGTGCCAGGTTCGTTTTGTACTTAATTTGCTATTATTGTGATGTGTATAAAATCTT TAATCTTGGTTCTTAGTACTTTGAATTGGTCTACAGGTATATTCCTGGGATGAAAGGATTGCCAAACCCAAATATAGACTAGATTATCCA ATGGGTTTGTGTCTTTGTTCCATTCTCAACATTTCTTCTTTCAACTATAAGTAATCCCCAGGTGTGGGGTAGCAAGTGTGCTTCCGTCAA GATACCATATTCTCCTGCTCCAGTATAACAGCTTGCAGGCAATAAAAATCTATTTGCTCATAACTACTTCTGTATTTATTAGACTTATAT AGAGCAAATGCAGTAAAAGAGGTTTGCAGTGTTTCAAACATCCCAACTATCTGACTCTGTGTTTTTGTTTCTTGAGTTTTTTGTTTGTTT TGTTTGTAATATTTTGTTTTTAATCAAATGAGTAAAAGATAGTAACACTGACTGTTCTTTGTACCTAATAGGCACATACATTGTTAAAAG AATTACTATGACAGCATATTTCCATAGCAGAGGAAATATATATTTCATATATTATTAGTTAATATTAGTAATCAATGTTAACTAATAATT AGTAATGTTAGTAATATTAACTAGTAATTCACATTATTAGTGGTTCTCTCAAAATATTTTCTTGCTAGGGTTTGAGAGATAATTGTATTA TGTTGCGTAAGTTCTCTATGAATTATTTTTGTGATATTTCCCAAAACATATTGGCAGATTGTGCTACTGCATTTATTAATAAGTAATTTT TAAATGAAGGCAGTTAATGCAGAATAAGTGGAGGTATCCCTGCATTTATGAAAACGTTTATTCTGAAACTTTAGAAATGAAACAACTTGG ACCTCCAGATTCGTTCTCCCATGGTGTAATAAGTGGTCGTTAGGTACCTAGACTAGCCTTAAAAATCTATTTAATCTACAGTTACTATTT AGCATTGTTTTGGCTCATTTTCTGGGCCCTAGGGCTAAGATAACAAACAAGGAAATTTCTTCCTTCTTCCGGGATTAAAGACTAACTCTA CCAACTCACTATCTTTGAAAGGCAGTTTGGGAATGTTCTCCCTCCTTTTCTTCTCTATTCACACACCAAATACTATTTTCTCCAAACCCT CAAATGTCCAGTCATGCTATCCCAAACTCTCCAATGGCACCATCCCCAAGCTTGCTGTTCCACGACACATTGCTCTGTACTTAGTAATTA >118_118_6_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000334010_length(amino acids)=1909AA_BP=728 MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLIL GVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHH LVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVIT SNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYI SYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL LRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLS KETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAD KMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQ GLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVV PKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGG CMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLSEFTDADRFQKHGMDEFISANPCKLDHA FLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIG TVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKI EETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTL LCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNGSA TSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLC ALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQD ILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVS -------------------------------------------------------------- >118_118_7_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000412584_length(transcript)=6167nt_BP=2319nt AAACACCTCCTACTTCCCGGCCTTCCATCCCAGTTTCTTCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCGGAAGATTCGAGGCGGCGG GGGACAAGTCGGCGCCCCAGAGCGGACGAGTCACCAGGTGTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGC CTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTCCGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAG CACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCT GGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACT TATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGAT TATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGA ATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTG CAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGT AATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTACCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGA GACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGAC AAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAAC ACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTA CCACACAAACTCGTGGCAATATGTGACATTTCAGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCC TTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCA CAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTT GAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTC CGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGCACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTA TTAGAATATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAAT ATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAGAAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCT TATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAA TTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACA ATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCA TTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTGATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAAT GTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCCATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGT ACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAG TTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAAACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTAT GAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTACAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAAC ATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGCTTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATT TACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGAATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTAT GAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAACACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCA GCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTGGCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGAT ATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTGAATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCG GAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCTGCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGAC GTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAAGTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATG GAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAAGCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCT CGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACTGGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCA ACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATGGTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTG CGAATGGATAAACCAGCACATATGAAGCATAGTGGATATCTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTT GTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGCAGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGC TATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAGGGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTT GCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAAGCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAA ACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCAGATGCTCAGCTTTATGCAGATCGTTTTCAGAAACATGGTATGGATGAGTTT ATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAATGATTCCTAT TCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCACAGACATCTC TGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTCTGTGCCTCT CATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGACTCTCTTCC CTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCATTACTTGAA AGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCTGCCTTGATC AATTACACTAGACTCACAGAATATGCCAAAATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATTCTTCATCTG GCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAGCATCATGCAGAGGCATTTGCCTGGTGGCCTGATTTATTGGCTGAACATGCA GAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGATAGTTTTCCTCTTTTCCAA CTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATCTTTGTACCCTTGGTTGTC CGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAGCCTGTCAACAATGGCTCA GCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAAATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCAC TTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAGGCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAG GCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGCACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTC TGTGCCCTGGATGGAGGACAAGAGTTTGGTAGTCAATGGCAACAGTACCATTCAAAAATAGATGATCTGATCGACAACAGTGTAAAAGAA ATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAGCTGTCAAGGTATGATGAAGGCACTTTCTTTTCA TCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCAGGAATGGATCTGGCAGACACCTATATTATGTTT GTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAAAAGTTATTTGATCAATGGTACAGCAGTTCCATG AAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAGCTGAAGACGCTCATCAAGATTGTGAAGAAAACC TACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTATGATACTGTGCACAGACGTTTAACAGTAGAGGAG GCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGTGACGAAGAAGAAGAAGGCTGATATCACACAGCT TTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCCTTGTAATTACATTCATTGTTTGTTTTGGCCAAA TAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATGTAGAGTAAAAGGGGAAATGCCAAGATTTTGGGGTTTTTTTGTTTCCTTTTT TTGTTTGTTTGTTTGTTTGTTTTTTTGGAGAAGAGCATCCTCTTTTGTGTAGTTTGACCTAAAAATGAACCTTGGCTCTGCTTGTGATCA GAACATGAACTTTTTTTTTTAAAGAAGATTTGAGCATTTTTCTGTAATCACATCAAAATGATGTTTTCTGTGTAAAGCGAGATACATATT >118_118_7_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000412584_length(amino acids)=1870AA_BP=728 MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLIL GVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHH LVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVIT SNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYI SYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL LRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLS KETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAD KMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQ GLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVV PKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGG CMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFR ILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSV EEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETM NQASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNG KFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEA CVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEG VLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQL -------------------------------------------------------------- >118_118_8_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000449022_length(transcript)=6033nt_BP=2319nt AAACACCTCCTACTTCCCGGCCTTCCATCCCAGTTTCTTCTAGGAATTCGGAGCCTCCCCTGCAGCGACTCGGAAGATTCGAGGCGGCGG GGGACAAGTCGGCGCCCCAGAGCGGACGAGTCACCAGGTGTCAAGATGCTGCAAGTACATAGGACTGGACTGGGCAGGCTGGGGGTCAGC CTCTCCAAGGGTCTTCACCACAAAGCTGTGTTGGCCGTCCGGAGGGAGGATGTGAACGCCTGGGAGAGAAGGGCCCCGCTAGCTCCCAAG CACATCAAAGGCATCACCAATCTGGGATACAAGGTCTTGATACAGCCTTCGAATCGGCGGGCCATTCATGATAAGGACTATGTCAAAGCT GGTGGCATTCTTCAGGAGGATATTTCTGAAGCTTGTCTAATTTTAGGAGTTAAAAGACCTCCAGAGGAAAAATTAATGTCCAGGAAGACT TATGCATTTTTCTCCCACACAATAAAAGCTCAGGAGGCCAATATGGGCTTGTTGGATGAGATTCTAAAACAGGAAATTCGCCTTATTGAT TATGAGAAAATGGTGGATCATAGAGGAGTACGGGTAGTGGCATTTGGACAGTGGGCTGGTGTGGCAGGAATGATCAACATTTTACATGGA ATGGGTTTAAGGCTCCTTGCTTTGGGACATCACACACCTTTTATGCACATTGGCATGGCTCATAACTACAGGAATAGCAGTCAGGCTGTG CAAGCTGTCCGTGATGCTGGCTATGAAATATCTTTGGGTTTGATGCCTAAGTCAATAGGACCCTTAACATTTGTGTTCACAGGAACTGGT AATGTTTCTAAGGGAGCCCAAGCAATCTTTAATGAGCTACCTTGTGAATATGTGGAGCCCCATGAATTAAAAGAAGTTTCCCAAACTGGA GACCTCAGAAAAGTGTATGGGACGGTGTTAAGTCGTCATCATCATCTTGTCAGGAAAACAGATGCTGTGTATGATCCTGCAGAGTATGAC AAACATCCGGAGCGCTACATAAGTCGTTTTAATACTGATATTGCACCCTATACAACTTGCTTAATTAATGGAATCTACTGGGAACAAAAC ACTCCTCGCCTCCTAACCCGCCAAGATGCTCAGAGTCTCCTGGCTCCGGGCAAGTTCTCACCTGCTGGTGTGGAAGGCTGCCCTGCATTA CCACACAAACTCGTGGCAATATGTGACATTTCAGCTGACACAGGAGGGTCTATAGAGTTTATGACTGAGTGTACAACAATAGAGCATCCC TTTTGCATGTATGATGCAGACCAGCATATTATTCATGACAGTGTTGAAGGCTCGGGGATCCTGATGTGTTCCATTGACAATTTGCCGGCA CAGCTCCCAATTGAAGCTACAGAATGCTTTGGAGACATGCTTTACCCTTATGTTGAAGAAATGATATTATCAGACGCGACACAGCCTCTT GAAAGTCAGAATTTTTCTCCTGTGGTGAGAGATGCAGTGATTACATCCAACGGTACATTACCTGATAAATATAAATATATCCAGACACTC CGGGAGAGCAGGGAACGTGCTCAGTCACTTTCAATGGGCACCAGGAGAAAGGTTTTGGTTCTTGGATCTGGCTACATATCTGAGCCTGTA TTAGAATATTTATCAAGAGATGGCAATATAGAAATAACAGTAGGATCTGACATGAAGAATCAAATTGAACAGTTAGGCAAGAAATATAAT ATTAATCCTGTTAGCATGGACATTTGTAAACAAGAAGAGAAGCTGGGCTTCTTGGTGGCAAAACAGGATCTTGTCATCAGCTTGTTGCCT TATGTATTGCACCCTCTTGTGGCCAAGGCCTGCATCACAAACAAAGTTAACATGGTCACTGCAAGCTACATCACACCAGCACTAAAAGAA TTGGAAAAGAGTGTGGAAGATGCTGGCATCACAATCATTGGTGAATTGGGATTGGACCCTGGTCTGGATCACATGTTAGCAATGGAAACA ATAGATAAAGCCAAGGAAGTGGGAGCCACGATTGAATCATATATTTCCTACTGTGGTGGGCTTCCAGCCCCTGAACATTCAAACAATCCA TTGAGATATAAATTTAGCTGGAGTCCAGTGGGAGTTTTGATGAATGTAATGCAGTCTGCCACCTATCTGCTCGATGGAAAGGTTGTGAAT GTTGCAGGAGGCATCTCCTTTCTTGATGCCGTTACGTCCATGGATTTTTTTCCAGGATTAAATTTGGAAGGCTATCCTAACAGAGACAGT ACGAAATATGCTGAGATTTATGGCATTTCTTCTGCTCACACTTTGTTGCGGGGGACACTGAGATATAAGCTTAACAAACAACAGTTGCAG TTACTGAAAGAACGGTTCCAGGCCTTCCTCAATGGGGAAACCCAAATTGTAGCTGACGAAGCATTTTGCAACGCAGTTCGGAGTTATTAT GAGGTTTTTCTAAAGAGTGACCGAGTGGCCAGAATGGTACAGAGTGGAGGGTGTTCTGCTAATGACTTCAGAGAAGTATTTAAGAAAAAC ATAGAAAAACGTGTGCGGAGTTTGCCAGAAATAGATGGCTTGAGCAAAGAGACAGTGTTGAGCTCATGGATAGCCAAATATGATGCCATT TACAGAGGTGAAGAGGACTTGTGCAAACAGCCAAATAGAATGGCCCTAAGTGCAGTGTCTGAACTTATTCTGAGCAAGGAACAACTCTAT GAAATGTTTCAGCAGATTCTGGGTATTAAAAAACTGGAACACCAGCTCCTTTATAATGCATGTCAGCTGGATAACGCAGATGAACAAGCA GCCCAGATCAGAAGGGAACTTGATGGCCGGCTGCAATTGGCAGATAAAATGGCAAAGGAAAGAAAATTCCCCAAATTTATAGCAAAAGAT ATGGAGAATATGTATATAGAAGAGTTGCGGTCTTCAGTGAATTTGCTAATGGCCAATTTGGAAAGTCTTCCAGTTTCGAAAGGTGGTCCG GAATTTAAATTACAAAAATTAAAACGTTCACAGAACTCTGCATTTTTGGACATAGGAGATGAGAATGAGATTCAGCTGTCAAAGTCCGAC GTGGTACTGTCATTCACCTTAGAGATTGTCATAATGGAAGTGCAAGGCCTGAAGTCAGTTGCTCCCAATCGAATTGTTTACTGTACAATG GAAGTGGAAGGAGAAAAACTTCAGACAGACCAGGCCGAAGCCTCAAGGCCACAATGGGGGACTCAAGGAGATTTCACCACCACCCATCCT CGGCCTGTGGTCAAAGTGAAACTCTTCACAGAAAGCACTGGAGTTCTGGCCCTGGAAGATAAAGAACTGGGAAGGGTGATATTATACCCA ACTTCTAATAGCTCCAAATCAGCTGAATTACACCGAATGGTAGTTCCAAAAAATAGCCAGGATTCTGACTTAAAAATCAAACTGGCAGTG CGAATGGATAAACCAGCACATATGAAGCATAGTGGATATCTGTATGCCCTTGGACAGAAGGTTTGGAAAAGATGGAAAAAACGTTACTTT GTTCTAGTTCAGGTTAGCCAATATACCTTTGCTATGTGCAGTTATAGAGAAAAGAAGTCTGAACCACAAGAATTAATGCAGCTTGAAGGC TATACTGTGGATTATACCGATCCCCACCCAGGCCTTCAGGGTGGTTGTATGTTCTTTAATGCTGTTAAAGAAGGAGATACTGTAATCTTT GCCAGTGATGATGAACAGGACAGAATATTATGGGTTCAAGCCATGTATAGGGCCACAGGTCAATCATATAAACCAGTTCCTGCAATTCAA ACCCAGAAACTGAATCCTAAAGGAGGAACTCTCCATGCAGATGCTCAGCTTTCTGGTAAAGATGCAGATCGTTTTCAGAAACATGGTATG GATGAGTTTATTTCTGCAAACCCCTGCAAGCTTGATCATGCCTTCCTTTTTAGAATACTCCAGAGGCAGACTTTGGATCACAGACTGAAT GATTCCTATTCTTGCTTGGGATGGTTTAGCCCTGGCCAAGTCTTTGTGTTAGATGAGTACTGTGCCCGTTATGGTGTGAGAGGCTGTCAC AGACATCTCTGCTACCTTGCAGAACTGATGGAACATTCAGAAAATGGTGCTGTCATTGACCCTACCCTGCTCCATTACAGCTTTGCATTC TGTGCCTCTCATGTGCACGGCAACAGGCCTGATGGAATTGGGACTGTTTCAGTGGAAGAAAAAGAAAGATTTGAGGAGATAAAAGAGAGA CTCTCTTCCCTTTTAGAAAATCAGATAAGCCATTTCAGATACTGTTTTCCCTTTGGACGACCTGAAGGTGCTCTAAAAGCTACACTTTCA TTACTTGAAAGGGTTTTAATGAAAGATATTGCCACTCCCATACCAGCAGAAGAGGTGAAGAAAGTGGTCAGAAAATGTCTCGAGAAAGCT GCCTTGATCAATTACACTAGACTCACAGAATATGCCAAAATAGAAGAGACCATGAACCAGGCATCTCCTGCTAGAAAGCTGGAAGAGATT CTTCATCTGGCAGAGCTCTGCATAGAAGTCTTACAGCAGAATGAAGAGCATCATGCAGAGGGAAGAGAGGCATTTGCCTGGTGGCCTGAT TTATTGGCTGAACATGCAGAGAAATTTTGGGCTTTATTTACAGTGGATATGGACACTGCACTAGAGGCTCAACCGCAAGACTCCTGGGAT AGTTTTCCTCTTTTCCAACTGCTTAATAATTTCCTCCGAAATGACACACTTTTGTGTAATGGAAAATTTCACAAACACTTGCAAGAAATC TTTGTACCCTTGGTTGTCCGCTATGTGGATCTCATGGAGTCTTCCATCGCCCAGTCAATTCACAGAGGTTTTGAGCAGGAGACATGGCAG CCTGTCAAGAATATCGCCAACAGTCTTCCCAATGTAGCTCTTCCAAAAGTTCCAAGTCTGCCTCTTAATCTTCCACAGATTCCTAACATT TCTACTGCTTCGTGGATGCCTTCTTTATATGAGTCCACCAATGGCTCAGCAACATCAGAAGACCTTTTTTGGAAGCTTGATGCACTGCAA ATGTTTGTCTTTGATCTGCACTGGCCAGAACAGGAATTTGCCCACCACTTAGAGCAAAGACTTAAACTAATGGCCAGTGATATGCTAGAG GCCTGTGTCAAAAGAACAAGAACTGCATTTGAACTCAAGCTACAAAAGGCAAGCAAAACAACTGACTTGCGCATTCCAGCTTCCGTTTGC ACTATGTTTAATGTATTAGTCGATGCCAAAAAGCAAAGCACCAAACTCTGTGCCCTGGATGGAGGACAAGAGCAACAGTACCATTCAAAA ATAGATGATCTGATCGACAACAGTGTAAAAGAAATCATTTCACTGTTAGTTTCAAAGTTTGTTTCAGTGTTGGAAGGCGTGTTGTCTAAG CTGTCAAGGTATGATGAAGGCACTTTCTTTTCATCCATTCTGTCATTCACTGTGAAAGCAGCTGCAAAATATGTTGATGTTCCAAAACCA GGAATGGATCTGGCAGACACCTATATTATGTTTGTTCGGCAAAACCAAGATATTCTTCGAGAAAAGGTCAATGAGGAAATGTATATAGAA AAGTTATTTGATCAATGGTACAGCAGTTCCATGAAAGTCATTTGCGTGTGGTTGACTGATAGATTAGACCTCCAACTCCATATTTACCAG CTGAAGACGCTCATCAAGATTGTGAAGAAAACCTACAGGGACTTTCGATTGCAGGGTGTGTTGGAAGGAACACTGAACAGTAAGACTTAT GATACTGTGCACAGACGTTTAACAGTAGAGGAGGCCACAGCCTCTGTTTCAGAAGGAGGAGGACTTCAGGGCATTACTATGAAAGACAGT GACGAAGAAGAAGAAGGCTGATATCACACAGCTTTGCAGAAGGAAGGAAGACCTTGATCGACATTGTTTTTTATTTTTTTAACCTTGTCC TTGTAATTACATTCATTGTTTGTTTTGGCCAAATAAAAATGCTTGTATTTCTTTAAAAAGTAAGCCTGAATGTAGAGTAAAAGGGGAAAT >118_118_8_AASS-CADPS2_AASS_chr7_121726066_ENST00000417368_CADPS2_chr7_122377122_ENST00000449022_length(amino acids)=1911AA_BP=728 MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLIL GVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHH LVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVIT SNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYI SYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL LRGTLRYKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLS KETVLSSWIAKYDAIYRGEEDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAD KMAKERKFPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDIGDENEIQLSKSDVVLSFTLEIVIMEVQ GLKSVAPNRIVYCTMEVEGEKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVV PKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGG CMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAF LFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGT VSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIE ETMNQASPARKLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRND TLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPNISTASWMPSLYESTNG SATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKASKTTDLRIPASVCTMFNVLVDAKKQSTK LCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQN QDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATAS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for AASS-CADPS2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000412584 | 0 | 28 | 755_1074 | 113.0 | 1256.0 | DRD2 | |
| Tgene | CADPS2 | chr7:121726066 | chr7:122377122 | ENST00000449022 | 0 | 30 | 755_1074 | 113.0 | 1297.0 | DRD2 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for AASS-CADPS2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for AASS-CADPS2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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