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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CABIN1-GSTT2 (FusionGDB2 ID:12230) |
Fusion Gene Summary for CABIN1-GSTT2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CABIN1-GSTT2 | Fusion gene ID: 12230 | Hgene | Tgene | Gene symbol | CABIN1 | GSTT2 | Gene ID | 23523 | 2953 |
| Gene name | calcineurin binding protein 1 | glutathione S-transferase theta 2 (gene/pseudogene) | |
| Synonyms | CAIN|KB-318B8.7|PPP3IN | - | |
| Cytomap | 22q11.23 | 22q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | calcineurin-binding protein cabin-1calcineurin binding protein cabin 1calcineurin inhibitor | glutathione S-transferase theta-2GST class-theta-2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q9Y6J0 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000263119, ENST00000398319, ENST00000405822, ENST00000337989, ENST00000485008, | ENST00000215780, ENST00000402588, | |
| Fusion gene scores | * DoF score | 16 X 15 X 8=1920 | 1 X 2 X 1=2 |
| # samples | 18 | 2 | |
| ** MAII score | log2(18/1920*10)=-3.41503749927884 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/2*10)=3.32192809488736 | |
| Context | PubMed: CABIN1 [Title/Abstract] AND GSTT2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CABIN1(24509715)-GSTT2(24323139), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CABIN1 | GO:0006336 | DNA replication-independent nucleosome assembly | 14718166 |
| Fusion gene breakpoints across CABIN1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GSTT2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SKCM | TCGA-GN-A4U4-06A | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| ChimerDB4 | SKCM | TCGA-GN-A4U4 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
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Fusion Gene ORF analysis for CABIN1-GSTT2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000263119 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| 5CDS-intron | ENST00000263119 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| 5CDS-intron | ENST00000398319 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| 5CDS-intron | ENST00000398319 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| 5CDS-intron | ENST00000405822 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| 5CDS-intron | ENST00000405822 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| In-frame | ENST00000263119 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| In-frame | ENST00000263119 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| In-frame | ENST00000398319 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| In-frame | ENST00000398319 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| In-frame | ENST00000405822 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| In-frame | ENST00000405822 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| intron-3CDS | ENST00000337989 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| intron-3CDS | ENST00000337989 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| intron-3CDS | ENST00000485008 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| intron-3CDS | ENST00000485008 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + |
| intron-intron | ENST00000337989 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| intron-intron | ENST00000337989 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| intron-intron | ENST00000485008 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| intron-intron | ENST00000485008 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24302568 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000263119 | CABIN1 | chr22 | 24509715 | + | ENST00000215780 | GSTT2 | chr22 | 24323139 | + | 5359 | 4427 | 121 | 5049 | 1642 |
| ENST00000263119 | CABIN1 | chr22 | 24509715 | + | ENST00000402588 | GSTT2 | chr22 | 24323139 | + | 5008 | 4427 | 121 | 5007 | 1629 |
| ENST00000405822 | CABIN1 | chr22 | 24509715 | + | ENST00000215780 | GSTT2 | chr22 | 24323139 | + | 5089 | 4157 | 88 | 4779 | 1563 |
| ENST00000405822 | CABIN1 | chr22 | 24509715 | + | ENST00000402588 | GSTT2 | chr22 | 24323139 | + | 4738 | 4157 | 88 | 4737 | 1550 |
| ENST00000398319 | CABIN1 | chr22 | 24509715 | + | ENST00000215780 | GSTT2 | chr22 | 24323139 | + | 5617 | 4685 | 379 | 5307 | 1642 |
| ENST00000398319 | CABIN1 | chr22 | 24509715 | + | ENST00000402588 | GSTT2 | chr22 | 24323139 | + | 5266 | 4685 | 379 | 5265 | 1629 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000263119 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.006749579 | 0.9932505 |
| ENST00000263119 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.006242336 | 0.9937577 |
| ENST00000405822 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.004550443 | 0.9954496 |
| ENST00000405822 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.007113725 | 0.99288625 |
| ENST00000398319 | ENST00000215780 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.008172833 | 0.99182713 |
| ENST00000398319 | ENST00000402588 | CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323139 | + | 0.007648262 | 0.9923517 |
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Fusion Genomic Features for CABIN1-GSTT2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323138 | + | 0.002842822 | 0.9971572 |
| CABIN1 | chr22 | 24509715 | + | GSTT2 | chr22 | 24323138 | + | 0.002842822 | 0.9971572 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CABIN1-GSTT2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:24509715/chr22:24323139) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CABIN1 | . |
| FUNCTION: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:9655484}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 1055_1088 | 1433 | 2221.0 | Repeat | Note=TPR 5 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 1106_1139 | 1433 | 2221.0 | Repeat | Note=TPR 6 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 125_157 | 1433 | 2221.0 | Repeat | Note=TPR 3 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 36_69 | 1433 | 2221.0 | Repeat | Note=TPR 1 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 615_648 | 1433 | 2221.0 | Repeat | Note=TPR 4 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000263119 | + | 27 | 37 | 90_123 | 1433 | 2221.0 | Repeat | Note=TPR 2 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 1055_1088 | 1433 | 2221.0 | Repeat | Note=TPR 5 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 1106_1139 | 1433 | 2221.0 | Repeat | Note=TPR 6 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 125_157 | 1433 | 2221.0 | Repeat | Note=TPR 3 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 36_69 | 1433 | 2221.0 | Repeat | Note=TPR 1 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 615_648 | 1433 | 2221.0 | Repeat | Note=TPR 4 |
| Hgene | CABIN1 | chr22:24509715 | chr22:24323139 | ENST00000398319 | + | 27 | 37 | 90_123 | 1433 | 2221.0 | Repeat | Note=TPR 2 |
| Tgene | GSTT2 | chr22:24509715 | chr22:24323139 | ENST00000215780 | 0 | 5 | 88_224 | 37 | 245.0 | Domain | Note=GST C-terminal | |
| Tgene | GSTT2 | chr22:24509715 | chr22:24323139 | ENST00000215780 | 0 | 5 | 53_54 | 37 | 245.0 | Region | Glutathione binding | |
| Tgene | GSTT2 | chr22:24509715 | chr22:24323139 | ENST00000215780 | 0 | 5 | 66_67 | 37 | 245.0 | Region | Glutathione binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GSTT2 | chr22:24509715 | chr22:24323139 | ENST00000215780 | 0 | 5 | 2_82 | 37 | 245.0 | Domain | Note=GST N-terminal |
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Fusion Gene Sequence for CABIN1-GSTT2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >12230_12230_1_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000263119_GSTT2_chr22_24323139_ENST00000215780_length(transcript)=5359nt_BP=4427nt AGCCGGACGGCGCGGTGGTCGGGACAGACTGGCCGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGA GAAGTGATGCTCGTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGA AGGAAGCTTTAAAAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAA ACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAA AGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGAC AGCCATGGAGTTCTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCAT CCGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCT GTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAA GGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGT GAGTGCAGCTGAGACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGA CCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGA GCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCC AGTTAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAAC CAGCTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAA ACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGT AGACTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGA AGTCCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAA GCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAA GTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCC GCTGCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCT GACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCA CTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTA CTGGCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTC CACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGA GGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGT TGTGCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGC CCAGCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGT CCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCT CTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGA CTGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGA GGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTC CCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCG AGTACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTA CTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGC ACTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCT ACTGAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAAC TGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAA CAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGC CCGGGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTG CTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTC ACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAA GCACTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAA GCAGCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGAT CCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCC CGATTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACC CAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCC CTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCA GGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG GGCCACAGAAGAAAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTT CATCTTGACCGAAAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCG TGCCCGTGTTCATGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACT CATTGGGGTCCAGGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGG GGACAGGCCCTTCCTCGCTGGCCAGCAGGTGACACTGGCTGATCTCATGGCCCTGGAGGAGCTGATGCAGCCGGTGGCTCTCGGCTATGA ACTGTTTGAGGGACGGCCACGACTGGCAGCATGGCGTGGACGAGTGGAGGCTTTCCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCAT CATCTTGAGCATCCTGGAACAGGCGGCCAAGAAAACCCTCCCAACACCCTCACCAGAGGCCTATCAGGCTATGCTGCTTCGAATCGCCAG GATCCCCTGAAGGGTCTGGGATGGGGGCCAGGAGATTAGCAACAAGGATTCATTCTGTTACTTACTTGCCCCTTTTTATCTTTCCCTCTT GCCCCAGTCCCTTCTCTCCAGCTTCATGTGAAGCTCTGCACAGACAAGACACTCAGTGTCCTTGGCAGTGCTGCTACTCCTCAGGTGCAG CATACATAACCAGTAAGAGACTAAATCTGCAATATATAAAGAGCTCCTACAAATCAGTAACATGAAGAACACTCAAAAATTGGCAAATGT >12230_12230_1_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000263119_GSTT2_chr22_24323139_ENST00000215780_length(amino acids)=1642AA_BP=1435 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGQHKS KEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKV ERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAK -------------------------------------------------------------- >12230_12230_2_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000263119_GSTT2_chr22_24323139_ENST00000402588_length(transcript)=5008nt_BP=4427nt AGCCGGACGGCGCGGTGGTCGGGACAGACTGGCCGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGA GAAGTGATGCTCGTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGA AGGAAGCTTTAAAAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAA ACATGACCGGTTTGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAA AGAGGGGTTGAAACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGAC AGCCATGGAGTTCTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCAT CCGGATCCCCCTGGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCT GTACACCCTCAGTGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAA GGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGT GAGTGCAGCTGAGACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGA CCTGAAACTTGTGCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGA GCCCCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCC AGTTAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAAC CAGCTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAA ACGGAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGT AGACTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGA AGTCCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAA GCAGGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAA GTTCTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCC GCTGCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCT GACCAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCA CTGCCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTA CTGGCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTC CACCGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGA GGAGATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGT TGTGCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGC CCAGCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGT CCAGCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCT CTCTGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGA CTGCAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGA GGAAGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTC CCTCATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCG AGTACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTA CTGCCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGC ACTGTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCT ACTGAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAAC TGAGGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAA CAAGGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGC CCGGGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTG CTTCCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTC ACGTCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAA GCACTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAA GCAGCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGAT CCACTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCC CGATTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACC CAAAGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCC CTCCTCCTCTGGCCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCA GGCAACGCCGGACGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG GGCCACAGAAGAAAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTT CATCTTGACCGAAAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCG TGCCCGTGTTCATGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACT CATTGGGGTCCAGGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGG GGACAGGCCCTTCCTCGCTGGCCAGCAGCCGGTGGCTCTCGGCTATGAACTGTTTGAGGGACGGCCACGACTGGCAGCATGGCGTGGACG AGTGGAGGCTTTCCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCATCATCTTGAGCATCCTGGAACAGGCGGCCAAGAAAACCCTCCC >12230_12230_2_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000263119_GSTT2_chr22_24323139_ENST00000402588_length(amino acids)=1629AA_BP=1435 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGQHKS KEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKV ERNRTAMDQALQWLEDKFLGDRPFLAGQQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAM -------------------------------------------------------------- >12230_12230_3_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000398319_GSTT2_chr22_24323139_ENST00000215780_length(transcript)=5617nt_BP=4685nt CTCAGCAGAGCCCGGGGCACAGGCCGGAGGGGCTGCAGGCGCGAGGCTGGGTTACGTGAGGAAGCTGGGGGTTTCGCGGGCAGCTTTAGA GCCCCAGTCAGGGAAACCGAGGCCGGGCTTCCTGGCTGCCTCGCGAGCCTCTTCATGGCTCTCGCCGCCGCCCTGAGGTGCCTAGAATGG GTTCCGGCCTCCGGGGAGGTTCCCAGTAACCGCAGGAGCCACCATTGATTTGGCGTCTGCTGGGTGCAAAGCCCAGCGCGCTAACCCTTT ACTCGCGACCTTTCGCTTCACCTTCACAGCAGCCCTGCGAGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTC GTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAA AAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTT TGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAA ACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTT CTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCT GGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAG TGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTT TGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCAGCTGA GACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGACCTGAAACTTGT GCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCCCCCACGTCC CAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGAT CCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGCTTCCCACT GCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACGGAAGAAGAT TTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGA GCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCAGA AGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCAGGACGTGCA TGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAG GTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGA CTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGACCAAAGGCAG AAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGA CCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGC TCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCACCGCCATCCA GGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGAGATTGATAA GAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCT CCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTGCTTCT TCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCAGCAGATGGT GAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAG CAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGC TGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGAAGACACCTT CCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCT GAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAA GGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTGCCTGTACAG CTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTCATGTT TGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAAT TGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAGGTACCCTG CCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTC CAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCG CATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTTCCGTCGGGC CCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACGTCAATTGAA GCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCAC ATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAGCAGCAGCC ACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCACTACCACAA CCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGT TGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCAGA AAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTCCTCCTCTGG CCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGA CGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGG CTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGGGGCCACAGAAGA AAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTTCATCTTGACCGA AAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCGTGCCCGTGTTCA TGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACTCATTGGGGTCCA GGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGGGGACAGGCCCTT CCTCGCTGGCCAGCAGGTGACACTGGCTGATCTCATGGCCCTGGAGGAGCTGATGCAGCCGGTGGCTCTCGGCTATGAACTGTTTGAGGG ACGGCCACGACTGGCAGCATGGCGTGGACGAGTGGAGGCTTTCCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCATCATCTTGAGCAT CCTGGAACAGGCGGCCAAGAAAACCCTCCCAACACCCTCACCAGAGGCCTATCAGGCTATGCTGCTTCGAATCGCCAGGATCCCCTGAAG GGTCTGGGATGGGGGCCAGGAGATTAGCAACAAGGATTCATTCTGTTACTTACTTGCCCCTTTTTATCTTTCCCTCTTGCCCCAGTCCCT TCTCTCCAGCTTCATGTGAAGCTCTGCACAGACAAGACACTCAGTGTCCTTGGCAGTGCTGCTACTCCTCAGGTGCAGCATACATAACCA GTAAGAGACTAAATCTGCAATATATAAAGAGCTCCTACAAATCAGTAACATGAAGAACACTCAAAAATTGGCAAATGTCATCAGTGTTTT >12230_12230_3_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000398319_GSTT2_chr22_24323139_ENST00000215780_length(amino acids)=1642AA_BP=1435 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGQHKS KEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKV ERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAK -------------------------------------------------------------- >12230_12230_4_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000398319_GSTT2_chr22_24323139_ENST00000402588_length(transcript)=5266nt_BP=4685nt CTCAGCAGAGCCCGGGGCACAGGCCGGAGGGGCTGCAGGCGCGAGGCTGGGTTACGTGAGGAAGCTGGGGGTTTCGCGGGCAGCTTTAGA GCCCCAGTCAGGGAAACCGAGGCCGGGCTTCCTGGCTGCCTCGCGAGCCTCTTCATGGCTCTCGCCGCCGCCCTGAGGTGCCTAGAATGG GTTCCGGCCTCCGGGGAGGTTCCCAGTAACCGCAGGAGCCACCATTGATTTGGCGTCTGCTGGGTGCAAAGCCCAGCGCGCTAACCCTTT ACTCGCGACCTTTCGCTTCACCTTCACAGCAGCCCTGCGAGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTC GTGGCAGTGCTGAATCTCTCTGAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAA AAGTCACAAAACCCAGACAAAGGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTT TGAGGAGTCTGCCAAAGCCTACCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAA ACACCCTGGGCTGATACTGAAATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTT CTACTTAGAGGCAGTGATGCTGGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCT GGCTCGCCATGCTTTTGAGGAAGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAG TGATTACACAACATGTCTGTACTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTT TGAGGAGCAGCCTTGTCTCCGGAAGGACTCTCTCAGAATGTTCCTCAAATGTGACATGTCGATTCACGATGTTTCGGTGAGTGCAGCTGA GACACAGGCGATTGTAGATGAGGCCTTGGGGCTGCGAAAAAAGAGGCAAGCGCTGATTGTGCGGGAGAAGGAGCCGGACCTGAAACTTGT GCAGCCCATTCCTTTCTTCACCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCCCCCACGTCC CAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGTTAACGTGAT CCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAGCTTCCCACT GCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACGGAAGAAGAT TTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGACTTCCAGGA GCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGTCCAGTCAGA AGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCAGGACGTGCA TGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTTCTTGGTAAG GTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCTGCTGAGGGA CTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGACCAAAGGCAG AAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTGCCTGGGTGA CCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTGGCTGAAGGC TCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCACCGCCATCCA GGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGAGATTGATAA GAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGTGCATCTGCT CCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCAGCTGCTTCT TCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCAGCAGATGGT GAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTCTGCGGACAG CAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTGCAGCATGGC TGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGAAGACACCTT CCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCTCATGCTGCT GAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGTACTCCAGAA GGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTGCCTGTACAG CTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACTGTTCATGTT TGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACTGAAGAGAAT TGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGAGGTACCCTG CCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAAGGAGCAGTC CAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCGGGCCAGCCG CATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTTCCGTCGGGC CCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACGTCAATTGAA GCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCACTGTTTCAC ATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCAGCAGCAGCC ACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCACTACCACAA CCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGATTCTGGGGT TGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAAAGCTTCAGA AAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTCCTCCTCTGG CCCAGGTCTGACATCCCCACCTTACACAGCCACTCCGATTGACCACGATTACGTCAAATGTAAAAAACCCCACCAGCAGGCAACGCCGGA CGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAGCTTACTGGAAGG CTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGGGGCCACAGAAGA AAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTTCATCTTGACCGA AAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCGTGCCCGTGTTCA TGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACTCATTGGGGTCCA GGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGGGGACAGGCCCTT CCTCGCTGGCCAGCAGCCGGTGGCTCTCGGCTATGAACTGTTTGAGGGACGGCCACGACTGGCAGCATGGCGTGGACGAGTGGAGGCTTT CCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCATCATCTTGAGCATCCTGGAACAGGCGGCCAAGAAAACCCTCCCAACACCCTCACC >12230_12230_4_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000398319_GSTT2_chr22_24323139_ENST00000402588_length(amino acids)=1629AA_BP=1435 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFF TWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLL ETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESF PSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHI KDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQ GDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCT SGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILK VSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEY LGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPK TLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFY MHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGEL PPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAM EALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPGLTSP PYTATPIDHDYVKCKKPHQQATPDDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGQHKS KEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKV ERNRTAMDQALQWLEDKFLGDRPFLAGQQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAM -------------------------------------------------------------- >12230_12230_5_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000405822_GSTT2_chr22_24323139_ENST00000215780_length(transcript)=5089nt_BP=4157nt CGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTCGTGGCAGTGCTGAATCTCTCT GAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGTCACAAAACCCAGACAAA GGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTA CCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAA ATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAGGCAGTGATGCT GGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCTGGCTCGCCATGCTTTTGAGGA AGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTA CTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCG GAAGGACTCTCTCAGAATGTTCCTCAAATGCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCC CCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGT TAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAG CTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACG GAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGA CTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGT CCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCA GGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTT CTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCT GCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGAC CAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTG CCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTG GCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCAC CGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGA GATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGT GCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCA GCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCA GCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTC TGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTG CAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGA AGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCT CATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGT ACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTG CCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACT GTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACT GAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGA GGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAA GGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCG GGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTT CCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACG TCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCA CTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCA GCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCA CTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGA TTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAA AGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTC CTCCTCTGGCCCAGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG GGCCACAGAAGAAAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTT CATCTTGACCGAAAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCG TGCCCGTGTTCATGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACT CATTGGGGTCCAGGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGG GGACAGGCCCTTCCTCGCTGGCCAGCAGGTGACACTGGCTGATCTCATGGCCCTGGAGGAGCTGATGCAGCCGGTGGCTCTCGGCTATGA ACTGTTTGAGGGACGGCCACGACTGGCAGCATGGCGTGGACGAGTGGAGGCTTTCCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCAT CATCTTGAGCATCCTGGAACAGGCGGCCAAGAAAACCCTCCCAACACCCTCACCAGAGGCCTATCAGGCTATGCTGCTTCGAATCGCCAG GATCCCCTGAAGGGTCTGGGATGGGGGCCAGGAGATTAGCAACAAGGATTCATTCTGTTACTTACTTGCCCCTTTTTATCTTTCCCTCTT GCCCCAGTCCCTTCTCTCCAGCTTCATGTGAAGCTCTGCACAGACAAGACACTCAGTGTCCTTGGCAGTGCTGCTACTCCTCAGGTGCAG CATACATAACCAGTAAGAGACTAAATCTGCAATATATAAAGAGCTCCTACAAATCAGTAACATGAAGAACACTCAAAAATTGGCAAATGT >12230_12230_5_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000405822_GSTT2_chr22_24323139_ENST00000215780_length(amino acids)=1563AA_BP=1356 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTP VNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKV DFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHK FLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTH CLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLE EIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAV QQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQE EDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFY CLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTST EVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNC FRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEK QQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTP KASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQ GATEERGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGP LIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHS -------------------------------------------------------------- >12230_12230_6_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000405822_GSTT2_chr22_24323139_ENST00000402588_length(transcript)=4738nt_BP=4157nt CGTTGCTGTGGAGACGCCTGGAGAGTTGTGGACTGGGGCAACCTTTGCCAGTGATGAGAAGTGATGCTCGTGGCAGTGCTGAATCTCTCT GAATATGATTCGAATTGCAGCCTTAAATGCCAGCTCCACCATTGAGGATGATCATGAAGGAAGCTTTAAAAGTCACAAAACCCAGACAAA GGAGGCTCAGGAAGCAGAGGCTTTTGCATTGTACCACAAGGCCCTTGATCTGCAGAAACATGACCGGTTTGAGGAGTCTGCCAAAGCCTA CCATGAGCTCTTGGAGGCGAGCCTGCTGCGGGAGGCAGTTTCATCCGGTGATGAGAAAGAGGGGTTGAAACACCCTGGGCTGATACTGAA ATATTCCACTTATAAGAACTTGGCCCAGCTGGCAGCCCAGCGGGAGGATCTGGAGACAGCCATGGAGTTCTACTTAGAGGCAGTGATGCT GGACTCCACAGATGTCAACCTCTGGTATAAGATTGGACATGTGGCCCTGAGGCTCATCCGGATCCCCCTGGCTCGCCATGCTTTTGAGGA AGGGCTGCGGTGCAATCCTGACCACTGGCCCTGTTTGGATAACCTAATCACTGTCCTGTACACCCTCAGTGATTACACAACATGTCTGTA CTTCATCTGCAAAGCTTTGGAGAAGGATTGCCGGTACAGCAAAGGGCTGGTCCTCAAGGAGAAGATTTTTGAGGAGCAGCCTTGTCTCCG GAAGGACTCTCTCAGAATGTTCCTCAAATGCTGGAAGTGCCTCGGAGAGAGCTTGCTGGCCATGTACAATCATCTCACCACCTGTGAGCC CCCACGTCCCAGCCTTGGCAAAAGGATTGATTTGTCGGACTACCAGGACCCCAGCCAGCCTCTTGAGTCCTCCATGGTGGTGACGCCAGT TAACGTGATCCAGCCAAGCACTGTCAGCACCAACCCAGCTGTGGCTGTCGCCGAGCCTGTGGTCTCCTACACCTCTGTGGCTACAACCAG CTTCCCACTGCACAGTCCTGGTCTGTTGGAGACAGGCGCTCCTGTGGGTGATATTTCTGGGGGAGATAAATCCAAGAAAGGGGTAAAACG GAAGAAGATTTCAGAAGAGAGTGGAGAAACAGCAAAGCGGCGGTCTGCCCGTGTCCGAAACACCAAGTGCAAAAAAGAAGAGAAAGTAGA CTTCCAGGAGCTTCTGATGAAGTTCTTGCCGTCCAGGTTAAGAAAGCTGGACCCTGAGGAGGAAGATGATTCCTTTAATAACTATGAAGT CCAGTCAGAAGCCAAACTGGAAAGCTTCCCAAGCATTGGGCCTCAAAGGCTGTCATTTGACTCAGCCACATTCATGGAATCTGAAAAGCA GGACGTGCATGAGTTCCTGCTGGAGAACCTAACCAACGGGGGCATCCTGGAGCTGATGATGCGCTACCTGAAAGCCATGGGCCACAAGTT CTTGGTAAGGTGGCCTCCAGGCTTGGCGGAGGTCGTGCTCAGCGTCTACCACAGCTGGAGGAGGCACAGCACCAGCCTGCCCAACCCGCT GCTGAGGGACTGCAGCAACAAGCACATCAAGGACATGATGCTGATGTCTCTCTCCTGCATGGAACTCCAGCTGGACCAGTGGCTGCTGAC CAAAGGCAGAAGCTCTGCAGTGTCTCCTCGGAACTGTCCTGCTGGTATGGTGAATGGCAGATTTGGACCTGACTTCCCAGGGACCCACTG CCTGGGTGACCTCCTACAGCTGTCATTTGCCTCGTCCCAGCGCGACCTGTTCGAGGATGGTTGGCTGGAGTTTGTGGTCCGTGTTTACTG GCTGAAGGCTCGCTTCCTGGCGCTGCAGGGAGACATGGAGCAGGCCCTGGAGAACTATGACATCTGCACAGAAATGCTCCAGAGTTCCAC CGCCATCCAGGTGGAGGCAGGGGCTGAACGAAGAGACATTGTCATCCGGCTGCCCAACCTCCATAATGACTCTGTGGTTTCCCTGGAGGA GATTGATAAGAACCTGAAGTCGCTGGAGCGGTGCCAGTCCCTGGAGGAGATTCAGCGGCTGTATGAAGCAGGCGACTACAAGGCTGTTGT GCATCTGCTCCGCCCCACTTTGTGCACCAGTGGGTTTGACCGGGCCAAACACCTGGAGTTTATGACTTCCATTCCTGAGAGGCCAGCCCA GCTGCTTCTTCTGCAGGACTCCTTGCTCCGGCTGAAGGACTATCGGCAGTGTTTTGAGTGTTCCGATGTGGCTCTGAACGAGGCTGTCCA GCAGATGGTGAACTCAGGTGAGGCTGCCGCCAAGGAGGAGTGGGTGGCCACAGTGACCCAACTGCTGATGGGCATCGAGCAGGCCCTCTC TGCGGACAGCAGTGGTAGCATCCTGAAGGTATCATCCTCCACCACTGGCCTTGTGCGGCTCACCAACAACCTCATCCAGGTCATTGACTG CAGCATGGCTGTGCAGGAGGAGGCCAAGGAGCCCCACGTCTCTTCAGTGCTACCCTGGATCATTCTACACCGGATCATCTGGCAGGAGGA AGACACCTTCCATTCTCTGTGCCACCAGCAGCAGCTCCAAAACCCAGCGGAGGAAGGGATGTCAGAGACGCCCATGCTCCCATCCTCCCT CATGCTGCTGAACACAGCCCACGAGTATTTGGGCAGAAGGTCCTGGTGCTGCAATTCAGATGGGGCTCTGCTGCGATTCTATGTGCGAGT ACTCCAGAAGGAACTGGCTGCATCCACCTCTGAAGACACGCACCCTTACAAGGAGGAGCTGGAGACAGCCTTGGAGCAGTGCTTCTACTG CCTGTACAGCTTCCCCAGCAAGAAGAGTAAGGCCAGGTACCTGGAGGAACACTCGGCCCAGCAGGTGGATCTTATATGGGAGGATGCACT GTTCATGTTTGAGTATTTTAAGCCCAAGACCCTTCCTGAATTTGACAGCTATAAGACCAGCACCGTGTCTGCTGACTTGGCCAACCTACT GAAGAGAATTGCCACCATTGTGCCTCGCACAGAGAGGCCAGCCCTTAGCCTGGACAAAGTCTCTGCCTACATTGAGGGAACTTCAACTGA GGTACCCTGCCTCCCAGAGGGGGCTGACCCCTCCCCTCCAGTGGTGAACGAGCTTTACTACCTCCTGGCTGATTATCATTTCAAAAACAA GGAGCAGTCCAAGGCCATCAAGTTCTACATGCATGACATCTGCATCTGCCCCAATAGGTTTGATTCCTGGGCAGGCATGGCTCTGGCCCG GGCCAGCCGCATTCAGGACAAGCTGAACTCCAATGAGCTGAAGAGTGATGGGCCCATTTGGAAGCATGCCACGCCCGTCTTGAACTGCTT CCGTCGGGCCCTGGAGATTGACAGCTCCAACTTGTCCCTATGGATTGAGTATGGCACCATGTCCTATGCCTTGCACTCATTCGCCTCACG TCAATTGAAGCAGTGGAGAGGCGAGCTGCCCCCTGAGCTCGTGCAGCAGATGGAGGGCCGGCGCGACAGCATGCTAGAGACAGCCAAGCA CTGTTTCACATCAGCAGCCCGCTGCGAGGGTGATGGTGACGAGGAGGAGTGGCTCATCCACTACATGCTGGGCAAGGTGGCTGAGAAGCA GCAGCAGCCACCCACCGTTTACTTGCTGCACTACAGGCAGGCTGGCCACTACCTGCACGAGGAGGCTGCCCGCTACCCCAAGAAGATCCA CTACCACAACCCACCTGAGCTGGCCATGGAGGCCCTGGAGGTGTACTTTCGGCTCCATGCTTCCATCCTGAAGCTCCTGGGGAAGCCCGA TTCTGGGGTTGGTGCAGAGGTCCTGGTCAACTTTATGAAGGAGGCTGCAGAAGGACCCTTTGCCAGGGGCGAGGAGAAGAACACACCCAA AGCTTCAGAAAAGGAGAAGGCCTGCCTGGTGGACGAGGACTCCCACTCTTCAGCTGGGACACTGCCGGGCCCCGGAGCCTCCCTCCCCTC CTCCTCTGGCCCAGACCGAAGCCAGGACAGCACAGCCGTAGCACTCTCAGACTCTAGCTCAACGCAGGACTTCTTTAATGAGCCCACCAG CTTACTGGAAGGCTCCAGGAAATCCTACACAGAGAAGAGGCTGCCCATTCTCAGTTCCCAAGCAGGAGCGACGGGTAAAGATCTTCAGGG GGCCACAGAAGAAAGAGGGCAGCACAAGAGCAAGGAGTTCTTGCAGATCAACAGCCTGGGGAAACTGCCGACGCTCAAGGATGGTGATTT CATCTTGACCGAAAGCTCGGCCATCCTGATTTACCTGAGCTGTAAGTACCAGACGCCGGACCACTGGTATCCATCTGACCTGCAGGCTCG TGCCCGTGTTCATGAGTACCTGGGCTGGCATGCCGACTGCATCCGTGGCACCTTTGGTATACCCCTGTGGGTCCAGGTGTTGGGGCCACT CATTGGGGTCCAGGTGCCCAAGGAGAAGGTGGAACGCAACAGGACTGCCATGGACCAGGCCCTGCAATGGCTGGAGGACAAGTTCCTGGG GGACAGGCCCTTCCTCGCTGGCCAGCAGCCGGTGGCTCTCGGCTATGAACTGTTTGAGGGACGGCCACGACTGGCAGCATGGCGTGGACG AGTGGAGGCTTTCCTGGGTGCTGAGCTATGCCAGGAGGCCCACAGCATCATCTTGAGCATCCTGGAACAGGCGGCCAAGAAAACCCTCCC >12230_12230_6_CABIN1-GSTT2_CABIN1_chr22_24509715_ENST00000405822_GSTT2_chr22_24323139_ENST00000402588_length(amino acids)=1550AA_BP=1356 MNMIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEASLLREAVSSGDEKEGLKHPGLIL KYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCL YFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCWKCLGESLLAMYNHLTTCEPPRPSLGKRIDLSDYQDPSQPLESSMVVTP VNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLETGAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKV DFQELLMKFLPSRLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLTNGGILELMMRYLKAMGHK FLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKDMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTH CLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERRDIVIRLPNLHNDSVVSLE EIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSGFDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAV QQMVNSGEAAAKEEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEPHVSSVLPWIILHRIIWQE EDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLGRRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFY CLYSFPSKKSKARYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTERPALSLDKVSAYIEGTST EVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMHDICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNC FRRALEIDSSNLSLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGDGDEEEWLIHYMLGKVAEK QQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTP KASEKEKACLVDEDSHSSAGTLPGPGASLPSSSGPDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQ GATEERGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGP LIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CABIN1-GSTT2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CABIN1-GSTT2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CABIN1-GSTT2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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