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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CADM1-PARD6G (FusionGDB2 ID:12445)

Fusion Gene Summary for CADM1-PARD6G

check button Fusion gene summary
Fusion gene informationFusion gene name: CADM1-PARD6G
Fusion gene ID: 12445
HgeneTgene
Gene symbol

CADM1

PARD6G

Gene ID

23705

84552

Gene namecell adhesion molecule 1par-6 family cell polarity regulator gamma
SynonymsBL2|IGSF4|IGSF4A|NECL2|Necl-2|RA175|ST17|SYNCAM|TSLC1|sTSLC-1|sgIGSF|synCAM1PAR-6G|PAR6gamma
Cytomap

11q23.3

18q23

Type of geneprotein-codingprotein-coding
Descriptioncell adhesion molecule 1TSLC-1TSLC1/Nectin-like 2/IGSF4immunoglobulin superfamily member 4immunoglobulin superfamily, member 4D variant 1immunoglobulin superfamily, member 4D variant 2nectin-like 2nectin-like protein 2spermatogenic immunoglobulin partitioning defective 6 homolog gammaPAR-6 gamma proteinPAR6Dpar-6 partitioning defective 6 homolog gamma
Modification date2020031320200327
UniProtAcc

Q9BY67

.
Ensembl transtripts involved in fusion geneENST00000537140, ENST00000331581, 
ENST00000452722, ENST00000536727, 
ENST00000537058, ENST00000542447, 
ENST00000353265, ENST00000470488, 
Fusion gene scores* DoF score7 X 5 X 4=14010 X 3 X 8=240
# samples 810
** MAII scorelog2(8/140*10)=-0.807354922057604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/240*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CADM1 [Title/Abstract] AND PARD6G [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCADM1(115374988)-PARD6G(77960815), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCADM1

GO:0001913

T cell mediated cytotoxicity

15811952

HgeneCADM1

GO:0008037

cell recognition

15811952

HgeneCADM1

GO:0042271

susceptibility to natural killer cell mediated cytotoxicity

15811952

HgeneCADM1

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

15811952

HgeneCADM1

GO:0050715

positive regulation of cytokine secretion

15811952

HgeneCADM1

GO:0050798

activated T cell proliferation

15811952

HgeneCADM1

GO:0051606

detection of stimulus

15811952


check buttonFusion gene breakpoints across CADM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PARD6G (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-1910CADM1chr11

115374988

-PARD6Gchr18

77960815

-


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Fusion Gene ORF analysis for CADM1-PARD6G

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000537140ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
5UTR-3CDSENST00000537140ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000331581ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000331581ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000452722ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000452722ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000536727ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000536727ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000537058ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000537058ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000542447ENST00000353265CADM1chr11

115374988

-PARD6Gchr18

77960815

-
In-frameENST00000542447ENST00000470488CADM1chr11

115374988

-PARD6Gchr18

77960815

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000452722CADM1chr11115374988-ENST00000353265PARD6Gchr1877960815-37431451721203343
ENST00000452722CADM1chr11115374988-ENST00000470488PARD6Gchr1877960815-66914539364784
ENST00000542447CADM1chr11115374988-ENST00000353265PARD6Gchr1877960815-38512532801311343
ENST00000542447CADM1chr11115374988-ENST00000470488PARD6Gchr1877960815-7772532361119
ENST00000537058CADM1chr11115374988-ENST00000353265PARD6Gchr1877960815-37431451721203343
ENST00000537058CADM1chr11115374988-ENST00000470488PARD6Gchr1877960815-66914539364784
ENST00000536727CADM1chr11115374988-ENST00000353265PARD6Gchr1877960815-37431451721203343
ENST00000536727CADM1chr11115374988-ENST00000470488PARD6Gchr1877960815-66914539364784
ENST00000331581CADM1chr11115374988-ENST00000353265PARD6Gchr1877960815-38932953221353343
ENST00000331581CADM1chr11115374988-ENST00000470488PARD6Gchr1877960815-81929544403119

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000452722ENST00000353265CADM1chr11115374988-PARD6Gchr1877960815-0.0046101590.9953898
ENST00000452722ENST00000470488CADM1chr11115374988-PARD6Gchr1877960815-0.169879110.83012086
ENST00000542447ENST00000353265CADM1chr11115374988-PARD6Gchr1877960815-0.0046985970.99530137
ENST00000542447ENST00000470488CADM1chr11115374988-PARD6Gchr1877960815-0.265648960.73435104
ENST00000537058ENST00000353265CADM1chr11115374988-PARD6Gchr1877960815-0.0046101590.9953898
ENST00000537058ENST00000470488CADM1chr11115374988-PARD6Gchr1877960815-0.169879110.83012086
ENST00000536727ENST00000353265CADM1chr11115374988-PARD6Gchr1877960815-0.0046101590.9953898
ENST00000536727ENST00000470488CADM1chr11115374988-PARD6Gchr1877960815-0.169879110.83012086
ENST00000331581ENST00000353265CADM1chr11115374988-PARD6Gchr1877960815-0.0047243990.9952756
ENST00000331581ENST00000470488CADM1chr11115374988-PARD6Gchr1877960815-0.269856630.7301433

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Fusion Genomic Features for CADM1-PARD6G


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CADM1-PARD6G


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:115374988/chr18:77960815)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CADM1

Q9BY67

.
FUNCTION: Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner (PubMed:22438059, PubMed:12050160). Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner (By similarity). Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo (PubMed:15811952). In mast cells, may mediate attachment to and promote communication with nerves (PubMed:15905536). CADM1, together with MITF, is essential for development and survival of mast cells in vivo (PubMed:22438059). By interacting with CRTAM and thus promoting the adhesion between CD8+ T-cells and CD8+ dendritic cells, regulates the retention of activated CD8+ T-cell within the draining lymph node (By similarity). Required for the intestinal retention of intraepithelial CD4+ CD8+ T-cells and, to a lesser extent, intraepithelial and lamina propria CD8+ T-cells and CD4+ T-cells (By similarity). Interaction with CRTAM promotes the adhesion to gut-associated CD103+ dendritic cells, which may facilitate the expression of gut-homing and adhesion molecules on T-cells and the conversion of CD4+ T-cells into CD4+ CD8+ T-cells (By similarity). Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons (By similarity). May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa (By similarity). Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells (PubMed:11279526, PubMed:12234973). May contribute to the less invasive phenotypes of lepidic growth tumor cells (PubMed:12920246). {ECO:0000250|UniProtKB:Q8R5M8, ECO:0000269|PubMed:11279526, ECO:0000269|PubMed:12050160, ECO:0000269|PubMed:12234973, ECO:0000269|PubMed:12920246, ECO:0000269|PubMed:15811952, ECO:0000269|PubMed:15905536, ECO:0000269|PubMed:22438059}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePARD6Gchr11:115374988chr18:77960815ENST0000035326503134_15124377.0DomainNote=Pseudo-CRIB
TgenePARD6Gchr11:115374988chr18:77960815ENST0000035326503158_25124377.0DomainPDZ
TgenePARD6Gchr11:115374988chr18:77960815ENST0000047048803134_15124108.0DomainNote=Pseudo-CRIB
TgenePARD6Gchr11:115374988chr18:77960815ENST0000047048803158_25124108.0DomainPDZ

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-112144_23841472.0DomainIg-like C2-type 1
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-112243_32941472.0DomainIg-like C2-type 2
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-11245_13941472.0DomainIg-like V-type
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-110144_23841443.0DomainIg-like C2-type 1
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-110243_32941443.0DomainIg-like C2-type 2
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-11045_13941443.0DomainIg-like V-type
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-111144_23841454.0DomainIg-like C2-type 1
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-111243_32941454.0DomainIg-like C2-type 2
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-11145_13941454.0DomainIg-like V-type
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-19144_23841415.0DomainIg-like C2-type 1
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-19243_32941415.0DomainIg-like C2-type 2
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-1945_13941415.0DomainIg-like V-type
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-112396_44241472.0Topological domainCytoplasmic
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-11245_37441472.0Topological domainExtracellular
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-110396_44241443.0Topological domainCytoplasmic
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-11045_37441443.0Topological domainExtracellular
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-111396_44241454.0Topological domainCytoplasmic
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-11145_37441454.0Topological domainExtracellular
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-19396_44241415.0Topological domainCytoplasmic
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-1945_37441415.0Topological domainExtracellular
HgeneCADM1chr11:115374988chr18:77960815ENST00000331581-112375_39541472.0TransmembraneHelical
HgeneCADM1chr11:115374988chr18:77960815ENST00000452722-110375_39541443.0TransmembraneHelical
HgeneCADM1chr11:115374988chr18:77960815ENST00000537058-111375_39541454.0TransmembraneHelical
HgeneCADM1chr11:115374988chr18:77960815ENST00000542447-19375_39541415.0TransmembraneHelical
TgenePARD6Gchr11:115374988chr18:77960815ENST000003532650318_9824377.0DomainPB1
TgenePARD6Gchr11:115374988chr18:77960815ENST000004704880318_9824108.0DomainPB1


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Fusion Gene Sequence for CADM1-PARD6G


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12445_12445_1_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000331581_PARD6G_chr18_77960815_ENST00000353265_length(transcript)=3893nt_BP=295nt
AGGGGGCGGGGTGGGGGAGGGAGCGAGGCCCTCCGAGAGCCGGGTTGGGCTCGCGGCGCTGTGATTGGTCTGCCCGGACTCCGCCTCCAG
CGCATGTCATTAGCATCTCATTAGCTGTCCGCTCGGGCTCCGGAGGCAGCCAACGCCGCCAGTCTGAGGCAGGTGCCCGACATGGCGAGT
GTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGGCTCCGGCTCCGGCTTCTGCTGTTGCTCTTC
TCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCGTCATAAGCCTGGGAAGTTTGAAGATTTCTA
CAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGATGTGCACGGAGACCTGCTGCCCATCAACAA
TGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCAGAAACGAGAGGAGGCCGAGCGTGGCAGCCT
CGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGCGCTGCGTGATGAAGGACCCCGGCGGCGTGCACACCTGGACATCGGCCT
CCCGCGCGACTTCCGCCCCGTATCATCCATCATCGATGTGGACCTGGTCCCCGAGACGCACCGGCGAGTGCGGCTGCACCGGCACGGCTG
CGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGTGCGCGTGACCCCGCACGGGCTGGAGAAGGTGCCCGGCATCTTCATCTC
GCGCATGGTACCCGGGGGCCTGGCGGAGAGCACCGGGCTGCTGGCTGTGAATGACGAGGTCCTGGAGGTGAACGGCATTGAGGTGGCCGG
GAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAGCCACAACCTCATCGTCACCGTCAAGCCCGCCAACCAGCGCAACAACGT
GGTGCGCGGCGGCCGCGCGTTGGGCAGCTCGGGACCGCCCTCGGACGGCACCGCGGGCTTCGTGGGTCCCCCCGCCCCGCGCGTCCTGCA
GAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGACGTCGTCATCGAGGGCACACTGGAGCCTGCACGTCCCCCCCAGACCCC
GGGCGCGCCCGCAGGCAGCCTCTCCCGGGTCAATGGCGCGGGCCTGGCGCAGCGGCTGCAGCGGGACCTGGCCCTGGACGGCGGCCTCCA
GCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCTGGCGCTGCCGCCAGGCGGCGTGGAGGAGCACGGGCCCGCGGTCACGCT
CTAGACTCCCGAGAGGCCCCCAAATCCTAGCTCCAGTTCCCCGGTAAGGACAGGGACAGGACCTGCAGACTGCATCCGCTCATTTTTTGT
TGTTTTTGTGACCACAAAAACAACGCTGCTCTTTGTTTCAACTTCCGGATATAAAAACACAAGTATTGCCTATTTTTATAGAATTTCGCC
ACAGAACTTAAAATGAACGCCTGTAGAGACACTCTATACCAGGCCTGAGTGCAGGTCTTGGCGCCTTTGCAAAGTGATAGAAAAGATCTG
ACCAAGTGCAAAAAAATGCTTTTTAAAATTTTTACAAATACTTTGTTTTTAAAGTGAAGCTTTAAAATTACTTTTTTAAAATAGTCAAAT
TCATGTTTTTAAGTAAGTTGGCCCATGCAACATATCTCAGCATTCTTGCTGTGCTCTCTGCTGACTTGCAGGCGAGGCCGACTGTGCTGA
TGTACGTGACAAGAGGCTGGTTTTTAATAACGAATGCAGCCAGGTGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCTACGT
GGGCTGATCACGAGGTCAGGAGGTCGAGACCAGCATGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATATAAAAATTAGCCAGGTGT
GGTGGCAGGCGCCTGTAATCCCAGCTACCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAG
ATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCGGGAAAAAAAAAAAATACACCCAAACCTGTCCATGTACAACC
ATGGAGATGAATTCCAGATTTTCACACTGTTCATAGTCATAATTCGGTTGGGACAGGAGAGCTCCCACCAGCACACTTATGGCACCCGCA
GCTGTGGAATTGTTCCGGGGCTTTTTTTTGTTTGTTTTGAGACATAGTGTCTTGTTCTGTCATCCAAGCTGGAGGGATCTCAGCTCACTG
CAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGACAGGCACATGCCACCATACCCAGCTAATTTT
TGTATTTTTAGTAGAGATGGGATTTCACCACGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATACGGTCCCCCCTCAGCCTCC
AAAAATGCTAGGATTATAGACGTGAGCCACAGCACCAGACCAGGGGCTATTTTTGTGACCCACATAGGTGGCCCATTCAGCCTCAAGGGG
AAATCCAGGGTAGGAAGCAGCAGCTCTGCTGGACTGGGCTCAGCAGTCCCATTTGGGATGTAAGCCTCTATTGCCTCTAAGATGACCCTT
TTCCTGTGGGTTGACTGACTCTGAGGGCGATTTCGGAAATGTTTTCAGCAGAAATGAAGGATAAGCATCGCACATGTCCAGCAATGTCTT
TGAGAATGCAGTCATTTGCACGTGAGTTCTCATCTTTGTTTTCTGAAACAGACGTTTCTTTTAGTAAGTCACAATACATGCTAATTTTCA
TTTCTAGAATGGTCACTGGCAGTTCTCACTTTTAACTATAAGAAGTCACGTGGAACTTAGTGATTTTTAACAAATACTAAATTCATCCTC
ACTTTATGTTGATCTTCCAGCAACGTTTATATATTTAGTAATTTTAAAAATTCCTATTTGATACAATTAAATTTTATATAATGTGTTTTG
CTTGAATAAAATGTTACATTTATACTTTGAGAACTCTGACCAAATCTTTCATACAGATACAGGTAAAGAAATATTTTTCTAGGTTGTCGG
AGCTGCGTACCTCCCGCTGCTTCTCCTTGTGGTCCAGCACCACCTGCTGGTCAGTGGCAGAACTGTCCTGACTTCGTGAACATGGAACTG
CTAAGAGGGAAAACTGCATCTCAGCATTTTCATTTTTTCTGAATATTAAGTGAAAAGCAAGTTCTATTTTTAAGAAATAGCTTTTGCTGA
GGAGTTGTGAATTCCTGCACCTGTGTTTGATGTTATTTGTATGCAATGGATTGCTGGCCCTTTGTTCCTAAGCAAGAGAAGACCAAAGAT
GCTTCCCCATGACCTCTCCGGTGAGGATCCGCACCCCCCGGACTTGCTCTCTGATGAAGGGCATGTCGTTCAGTGCCCCAGCAGTCAGAA
GCAGTTTTTGTGGAACTAAAACTAATAATGTTACCCTCACAAAGGAAATGTTCTTTTACTAAGTTATTGCTGATTCTTGAATGTCTGTTA
TATAACTGGGTCGGCTATCAAGAAGGAAGGTTATATTTCTTATCACATTTTAAGTTGTTAAGCAAATGTGAGTTTTTTTTTAAGAAATGA
GGCTTTCACTGAGATTTGTGTGCTATTCATAATTTTAGGAATTACTGCTTAGAACAGCTGCTTGGGTGTATTTTTCTACACAGGTCTGTA
CTTCTGCCACTTTCTCCTTTTAAAAAAACAAAACTATGCATATTATGTATTAAAGTTTTCTTGGTTTTATATATCAGAGAATAAAAACTT

>12445_12445_1_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000331581_PARD6G_chr18_77960815_ENST00000353265_length(amino acids)=343AA_BP=
MDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRD
EGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN
DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVI

--------------------------------------------------------------
>12445_12445_2_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000331581_PARD6G_chr18_77960815_ENST00000470488_length(transcript)=819nt_BP=295nt
AGGGGGCGGGGTGGGGGAGGGAGCGAGGCCCTCCGAGAGCCGGGTTGGGCTCGCGGCGCTGTGATTGGTCTGCCCGGACTCCGCCTCCAG
CGCATGTCATTAGCATCTCATTAGCTGTCCGCTCGGGCTCCGGAGGCAGCCAACGCCGCCAGTCTGAGGCAGGTGCCCGACATGGCGAGT
GTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGGCTCCGGCTCCGGCTTCTGCTGTTGCTCTTC
TCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCGTCATAAGCCTGGGAAGTTTGAAGATTTCTA
CAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGATGTGCACGGAGACCTGCTGCCCATCAACAA
TGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCAGAAACGAGATGACGGAGCCCTGCGACCAGG
AACCTGACTCTTCAGCTCAAATCTTGGTTTGAAAGGGGGACTTCTCTGTGCCCCTGTTGTCGGCATGCCATGGTAGAGAATGGATGGCCC
ACGCAGCTGGCCCCTCATGAGACCCCAGCCATCTCATTCCACTGGGAGCCACGTCAGGACGAAGGAGGACTGGGAGGGGCGTCTGGCTGC
GTGGTGTGGGGCCTGCAGTGTTGTGGCACACGCAGCTTCAGCCAAACATCTAGCCCTGTACCTAGAACTAAGAAATAAAACTATAACATC

>12445_12445_2_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000331581_PARD6G_chr18_77960815_ENST00000470488_length(amino acids)=119AA_BP=83
MGSRRCDWSARTPPPAHVISISLAVRSGSGGSQRRQSEAGARHGECSAAERIPVCGGSGGGGASRAPAPASAVALLRRGTDPHSLGRNSE

--------------------------------------------------------------
>12445_12445_3_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000452722_PARD6G_chr18_77960815_ENST00000353265_length(transcript)=3743nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGAGGAGGCCGAGCGTGGCAGCCTCGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGCGCTGCGTGATGAAGGACC
CCGGCGGCGTGCACACCTGGACATCGGCCTCCCGCGCGACTTCCGCCCCGTATCATCCATCATCGATGTGGACCTGGTCCCCGAGACGCA
CCGGCGAGTGCGGCTGCACCGGCACGGCTGCGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGTGCGCGTGACCCCGCACGG
GCTGGAGAAGGTGCCCGGCATCTTCATCTCGCGCATGGTACCCGGGGGCCTGGCGGAGAGCACCGGGCTGCTGGCTGTGAATGACGAGGT
CCTGGAGGTGAACGGCATTGAGGTGGCCGGGAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAGCCACAACCTCATCGTCAC
CGTCAAGCCCGCCAACCAGCGCAACAACGTGGTGCGCGGCGGCCGCGCGTTGGGCAGCTCGGGACCGCCCTCGGACGGCACCGCGGGCTT
CGTGGGTCCCCCCGCCCCGCGCGTCCTGCAGAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGACGTCGTCATCGAGGGCAC
ACTGGAGCCTGCACGTCCCCCCCAGACCCCGGGCGCGCCCGCAGGCAGCCTCTCCCGGGTCAATGGCGCGGGCCTGGCGCAGCGGCTGCA
GCGGGACCTGGCCCTGGACGGCGGCCTCCAGCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCTGGCGCTGCCGCCAGGCGG
CGTGGAGGAGCACGGGCCCGCGGTCACGCTCTAGACTCCCGAGAGGCCCCCAAATCCTAGCTCCAGTTCCCCGGTAAGGACAGGGACAGG
ACCTGCAGACTGCATCCGCTCATTTTTTGTTGTTTTTGTGACCACAAAAACAACGCTGCTCTTTGTTTCAACTTCCGGATATAAAAACAC
AAGTATTGCCTATTTTTATAGAATTTCGCCACAGAACTTAAAATGAACGCCTGTAGAGACACTCTATACCAGGCCTGAGTGCAGGTCTTG
GCGCCTTTGCAAAGTGATAGAAAAGATCTGACCAAGTGCAAAAAAATGCTTTTTAAAATTTTTACAAATACTTTGTTTTTAAAGTGAAGC
TTTAAAATTACTTTTTTAAAATAGTCAAATTCATGTTTTTAAGTAAGTTGGCCCATGCAACATATCTCAGCATTCTTGCTGTGCTCTCTG
CTGACTTGCAGGCGAGGCCGACTGTGCTGATGTACGTGACAAGAGGCTGGTTTTTAATAACGAATGCAGCCAGGTGCAGTGGCTCACGTC
TGTAATCCCAGCACTTTGGGAGGCCTACGTGGGCTGATCACGAGGTCAGGAGGTCGAGACCAGCATGGCCAACATGGTGAAACCCTGTCT
CTACTAAAAATATAAAAATTAGCCAGGTGTGGTGGCAGGCGCCTGTAATCCCAGCTACCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCGGGAAAAAAAAA
AAATACACCCAAACCTGTCCATGTACAACCATGGAGATGAATTCCAGATTTTCACACTGTTCATAGTCATAATTCGGTTGGGACAGGAGA
GCTCCCACCAGCACACTTATGGCACCCGCAGCTGTGGAATTGTTCCGGGGCTTTTTTTTGTTTGTTTTGAGACATAGTGTCTTGTTCTGT
CATCCAAGCTGGAGGGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGAC
AGGCACATGCCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACCACGTTGGTCAGGCTGGTCTTGAACTCCTGAC
CTCAGGTGATACGGTCCCCCCTCAGCCTCCAAAAATGCTAGGATTATAGACGTGAGCCACAGCACCAGACCAGGGGCTATTTTTGTGACC
CACATAGGTGGCCCATTCAGCCTCAAGGGGAAATCCAGGGTAGGAAGCAGCAGCTCTGCTGGACTGGGCTCAGCAGTCCCATTTGGGATG
TAAGCCTCTATTGCCTCTAAGATGACCCTTTTCCTGTGGGTTGACTGACTCTGAGGGCGATTTCGGAAATGTTTTCAGCAGAAATGAAGG
ATAAGCATCGCACATGTCCAGCAATGTCTTTGAGAATGCAGTCATTTGCACGTGAGTTCTCATCTTTGTTTTCTGAAACAGACGTTTCTT
TTAGTAAGTCACAATACATGCTAATTTTCATTTCTAGAATGGTCACTGGCAGTTCTCACTTTTAACTATAAGAAGTCACGTGGAACTTAG
TGATTTTTAACAAATACTAAATTCATCCTCACTTTATGTTGATCTTCCAGCAACGTTTATATATTTAGTAATTTTAAAAATTCCTATTTG
ATACAATTAAATTTTATATAATGTGTTTTGCTTGAATAAAATGTTACATTTATACTTTGAGAACTCTGACCAAATCTTTCATACAGATAC
AGGTAAAGAAATATTTTTCTAGGTTGTCGGAGCTGCGTACCTCCCGCTGCTTCTCCTTGTGGTCCAGCACCACCTGCTGGTCAGTGGCAG
AACTGTCCTGACTTCGTGAACATGGAACTGCTAAGAGGGAAAACTGCATCTCAGCATTTTCATTTTTTCTGAATATTAAGTGAAAAGCAA
GTTCTATTTTTAAGAAATAGCTTTTGCTGAGGAGTTGTGAATTCCTGCACCTGTGTTTGATGTTATTTGTATGCAATGGATTGCTGGCCC
TTTGTTCCTAAGCAAGAGAAGACCAAAGATGCTTCCCCATGACCTCTCCGGTGAGGATCCGCACCCCCCGGACTTGCTCTCTGATGAAGG
GCATGTCGTTCAGTGCCCCAGCAGTCAGAAGCAGTTTTTGTGGAACTAAAACTAATAATGTTACCCTCACAAAGGAAATGTTCTTTTACT
AAGTTATTGCTGATTCTTGAATGTCTGTTATATAACTGGGTCGGCTATCAAGAAGGAAGGTTATATTTCTTATCACATTTTAAGTTGTTA
AGCAAATGTGAGTTTTTTTTTAAGAAATGAGGCTTTCACTGAGATTTGTGTGCTATTCATAATTTTAGGAATTACTGCTTAGAACAGCTG
CTTGGGTGTATTTTTCTACACAGGTCTGTACTTCTGCCACTTTCTCCTTTTAAAAAAACAAAACTATGCATATTATGTATTAAAGTTTTC

>12445_12445_3_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000452722_PARD6G_chr18_77960815_ENST00000353265_length(amino acids)=343AA_BP=
MDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRD
EGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN
DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVI

--------------------------------------------------------------
>12445_12445_4_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000452722_PARD6G_chr18_77960815_ENST00000470488_length(transcript)=669nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGATGACGGAGCCCTGCGACCAGGAACCTGACTCTTCAGCTCAAATCTTGGTTTGAAAGGGGGACTTCTCTGTGCCCCTGTTGT
CGGCATGCCATGGTAGAGAATGGATGGCCCACGCAGCTGGCCCCTCATGAGACCCCAGCCATCTCATTCCACTGGGAGCCACGTCAGGAC
GAAGGAGGACTGGGAGGGGCGTCTGGCTGCGTGGTGTGGGGCCTGCAGTGTTGTGGCACACGCAGCTTCAGCCAAACATCTAGCCCTGTA

>12445_12445_4_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000452722_PARD6G_chr18_77960815_ENST00000470488_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>12445_12445_5_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000536727_PARD6G_chr18_77960815_ENST00000353265_length(transcript)=3743nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGAGGAGGCCGAGCGTGGCAGCCTCGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGCGCTGCGTGATGAAGGACC
CCGGCGGCGTGCACACCTGGACATCGGCCTCCCGCGCGACTTCCGCCCCGTATCATCCATCATCGATGTGGACCTGGTCCCCGAGACGCA
CCGGCGAGTGCGGCTGCACCGGCACGGCTGCGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGTGCGCGTGACCCCGCACGG
GCTGGAGAAGGTGCCCGGCATCTTCATCTCGCGCATGGTACCCGGGGGCCTGGCGGAGAGCACCGGGCTGCTGGCTGTGAATGACGAGGT
CCTGGAGGTGAACGGCATTGAGGTGGCCGGGAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAGCCACAACCTCATCGTCAC
CGTCAAGCCCGCCAACCAGCGCAACAACGTGGTGCGCGGCGGCCGCGCGTTGGGCAGCTCGGGACCGCCCTCGGACGGCACCGCGGGCTT
CGTGGGTCCCCCCGCCCCGCGCGTCCTGCAGAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGACGTCGTCATCGAGGGCAC
ACTGGAGCCTGCACGTCCCCCCCAGACCCCGGGCGCGCCCGCAGGCAGCCTCTCCCGGGTCAATGGCGCGGGCCTGGCGCAGCGGCTGCA
GCGGGACCTGGCCCTGGACGGCGGCCTCCAGCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCTGGCGCTGCCGCCAGGCGG
CGTGGAGGAGCACGGGCCCGCGGTCACGCTCTAGACTCCCGAGAGGCCCCCAAATCCTAGCTCCAGTTCCCCGGTAAGGACAGGGACAGG
ACCTGCAGACTGCATCCGCTCATTTTTTGTTGTTTTTGTGACCACAAAAACAACGCTGCTCTTTGTTTCAACTTCCGGATATAAAAACAC
AAGTATTGCCTATTTTTATAGAATTTCGCCACAGAACTTAAAATGAACGCCTGTAGAGACACTCTATACCAGGCCTGAGTGCAGGTCTTG
GCGCCTTTGCAAAGTGATAGAAAAGATCTGACCAAGTGCAAAAAAATGCTTTTTAAAATTTTTACAAATACTTTGTTTTTAAAGTGAAGC
TTTAAAATTACTTTTTTAAAATAGTCAAATTCATGTTTTTAAGTAAGTTGGCCCATGCAACATATCTCAGCATTCTTGCTGTGCTCTCTG
CTGACTTGCAGGCGAGGCCGACTGTGCTGATGTACGTGACAAGAGGCTGGTTTTTAATAACGAATGCAGCCAGGTGCAGTGGCTCACGTC
TGTAATCCCAGCACTTTGGGAGGCCTACGTGGGCTGATCACGAGGTCAGGAGGTCGAGACCAGCATGGCCAACATGGTGAAACCCTGTCT
CTACTAAAAATATAAAAATTAGCCAGGTGTGGTGGCAGGCGCCTGTAATCCCAGCTACCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCGGGAAAAAAAAA
AAATACACCCAAACCTGTCCATGTACAACCATGGAGATGAATTCCAGATTTTCACACTGTTCATAGTCATAATTCGGTTGGGACAGGAGA
GCTCCCACCAGCACACTTATGGCACCCGCAGCTGTGGAATTGTTCCGGGGCTTTTTTTTGTTTGTTTTGAGACATAGTGTCTTGTTCTGT
CATCCAAGCTGGAGGGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGAC
AGGCACATGCCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACCACGTTGGTCAGGCTGGTCTTGAACTCCTGAC
CTCAGGTGATACGGTCCCCCCTCAGCCTCCAAAAATGCTAGGATTATAGACGTGAGCCACAGCACCAGACCAGGGGCTATTTTTGTGACC
CACATAGGTGGCCCATTCAGCCTCAAGGGGAAATCCAGGGTAGGAAGCAGCAGCTCTGCTGGACTGGGCTCAGCAGTCCCATTTGGGATG
TAAGCCTCTATTGCCTCTAAGATGACCCTTTTCCTGTGGGTTGACTGACTCTGAGGGCGATTTCGGAAATGTTTTCAGCAGAAATGAAGG
ATAAGCATCGCACATGTCCAGCAATGTCTTTGAGAATGCAGTCATTTGCACGTGAGTTCTCATCTTTGTTTTCTGAAACAGACGTTTCTT
TTAGTAAGTCACAATACATGCTAATTTTCATTTCTAGAATGGTCACTGGCAGTTCTCACTTTTAACTATAAGAAGTCACGTGGAACTTAG
TGATTTTTAACAAATACTAAATTCATCCTCACTTTATGTTGATCTTCCAGCAACGTTTATATATTTAGTAATTTTAAAAATTCCTATTTG
ATACAATTAAATTTTATATAATGTGTTTTGCTTGAATAAAATGTTACATTTATACTTTGAGAACTCTGACCAAATCTTTCATACAGATAC
AGGTAAAGAAATATTTTTCTAGGTTGTCGGAGCTGCGTACCTCCCGCTGCTTCTCCTTGTGGTCCAGCACCACCTGCTGGTCAGTGGCAG
AACTGTCCTGACTTCGTGAACATGGAACTGCTAAGAGGGAAAACTGCATCTCAGCATTTTCATTTTTTCTGAATATTAAGTGAAAAGCAA
GTTCTATTTTTAAGAAATAGCTTTTGCTGAGGAGTTGTGAATTCCTGCACCTGTGTTTGATGTTATTTGTATGCAATGGATTGCTGGCCC
TTTGTTCCTAAGCAAGAGAAGACCAAAGATGCTTCCCCATGACCTCTCCGGTGAGGATCCGCACCCCCCGGACTTGCTCTCTGATGAAGG
GCATGTCGTTCAGTGCCCCAGCAGTCAGAAGCAGTTTTTGTGGAACTAAAACTAATAATGTTACCCTCACAAAGGAAATGTTCTTTTACT
AAGTTATTGCTGATTCTTGAATGTCTGTTATATAACTGGGTCGGCTATCAAGAAGGAAGGTTATATTTCTTATCACATTTTAAGTTGTTA
AGCAAATGTGAGTTTTTTTTTAAGAAATGAGGCTTTCACTGAGATTTGTGTGCTATTCATAATTTTAGGAATTACTGCTTAGAACAGCTG
CTTGGGTGTATTTTTCTACACAGGTCTGTACTTCTGCCACTTTCTCCTTTTAAAAAAACAAAACTATGCATATTATGTATTAAAGTTTTC

>12445_12445_5_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000536727_PARD6G_chr18_77960815_ENST00000353265_length(amino acids)=343AA_BP=
MDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRD
EGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN
DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVI

--------------------------------------------------------------
>12445_12445_6_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000536727_PARD6G_chr18_77960815_ENST00000470488_length(transcript)=669nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGATGACGGAGCCCTGCGACCAGGAACCTGACTCTTCAGCTCAAATCTTGGTTTGAAAGGGGGACTTCTCTGTGCCCCTGTTGT
CGGCATGCCATGGTAGAGAATGGATGGCCCACGCAGCTGGCCCCTCATGAGACCCCAGCCATCTCATTCCACTGGGAGCCACGTCAGGAC
GAAGGAGGACTGGGAGGGGCGTCTGGCTGCGTGGTGTGGGGCCTGCAGTGTTGTGGCACACGCAGCTTCAGCCAAACATCTAGCCCTGTA

>12445_12445_6_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000536727_PARD6G_chr18_77960815_ENST00000470488_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>12445_12445_7_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000537058_PARD6G_chr18_77960815_ENST00000353265_length(transcript)=3743nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGAGGAGGCCGAGCGTGGCAGCCTCGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGCGCTGCGTGATGAAGGACC
CCGGCGGCGTGCACACCTGGACATCGGCCTCCCGCGCGACTTCCGCCCCGTATCATCCATCATCGATGTGGACCTGGTCCCCGAGACGCA
CCGGCGAGTGCGGCTGCACCGGCACGGCTGCGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGTGCGCGTGACCCCGCACGG
GCTGGAGAAGGTGCCCGGCATCTTCATCTCGCGCATGGTACCCGGGGGCCTGGCGGAGAGCACCGGGCTGCTGGCTGTGAATGACGAGGT
CCTGGAGGTGAACGGCATTGAGGTGGCCGGGAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAGCCACAACCTCATCGTCAC
CGTCAAGCCCGCCAACCAGCGCAACAACGTGGTGCGCGGCGGCCGCGCGTTGGGCAGCTCGGGACCGCCCTCGGACGGCACCGCGGGCTT
CGTGGGTCCCCCCGCCCCGCGCGTCCTGCAGAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGACGTCGTCATCGAGGGCAC
ACTGGAGCCTGCACGTCCCCCCCAGACCCCGGGCGCGCCCGCAGGCAGCCTCTCCCGGGTCAATGGCGCGGGCCTGGCGCAGCGGCTGCA
GCGGGACCTGGCCCTGGACGGCGGCCTCCAGCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCTGGCGCTGCCGCCAGGCGG
CGTGGAGGAGCACGGGCCCGCGGTCACGCTCTAGACTCCCGAGAGGCCCCCAAATCCTAGCTCCAGTTCCCCGGTAAGGACAGGGACAGG
ACCTGCAGACTGCATCCGCTCATTTTTTGTTGTTTTTGTGACCACAAAAACAACGCTGCTCTTTGTTTCAACTTCCGGATATAAAAACAC
AAGTATTGCCTATTTTTATAGAATTTCGCCACAGAACTTAAAATGAACGCCTGTAGAGACACTCTATACCAGGCCTGAGTGCAGGTCTTG
GCGCCTTTGCAAAGTGATAGAAAAGATCTGACCAAGTGCAAAAAAATGCTTTTTAAAATTTTTACAAATACTTTGTTTTTAAAGTGAAGC
TTTAAAATTACTTTTTTAAAATAGTCAAATTCATGTTTTTAAGTAAGTTGGCCCATGCAACATATCTCAGCATTCTTGCTGTGCTCTCTG
CTGACTTGCAGGCGAGGCCGACTGTGCTGATGTACGTGACAAGAGGCTGGTTTTTAATAACGAATGCAGCCAGGTGCAGTGGCTCACGTC
TGTAATCCCAGCACTTTGGGAGGCCTACGTGGGCTGATCACGAGGTCAGGAGGTCGAGACCAGCATGGCCAACATGGTGAAACCCTGTCT
CTACTAAAAATATAAAAATTAGCCAGGTGTGGTGGCAGGCGCCTGTAATCCCAGCTACCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCGGGAAAAAAAAA
AAATACACCCAAACCTGTCCATGTACAACCATGGAGATGAATTCCAGATTTTCACACTGTTCATAGTCATAATTCGGTTGGGACAGGAGA
GCTCCCACCAGCACACTTATGGCACCCGCAGCTGTGGAATTGTTCCGGGGCTTTTTTTTGTTTGTTTTGAGACATAGTGTCTTGTTCTGT
CATCCAAGCTGGAGGGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGAC
AGGCACATGCCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACCACGTTGGTCAGGCTGGTCTTGAACTCCTGAC
CTCAGGTGATACGGTCCCCCCTCAGCCTCCAAAAATGCTAGGATTATAGACGTGAGCCACAGCACCAGACCAGGGGCTATTTTTGTGACC
CACATAGGTGGCCCATTCAGCCTCAAGGGGAAATCCAGGGTAGGAAGCAGCAGCTCTGCTGGACTGGGCTCAGCAGTCCCATTTGGGATG
TAAGCCTCTATTGCCTCTAAGATGACCCTTTTCCTGTGGGTTGACTGACTCTGAGGGCGATTTCGGAAATGTTTTCAGCAGAAATGAAGG
ATAAGCATCGCACATGTCCAGCAATGTCTTTGAGAATGCAGTCATTTGCACGTGAGTTCTCATCTTTGTTTTCTGAAACAGACGTTTCTT
TTAGTAAGTCACAATACATGCTAATTTTCATTTCTAGAATGGTCACTGGCAGTTCTCACTTTTAACTATAAGAAGTCACGTGGAACTTAG
TGATTTTTAACAAATACTAAATTCATCCTCACTTTATGTTGATCTTCCAGCAACGTTTATATATTTAGTAATTTTAAAAATTCCTATTTG
ATACAATTAAATTTTATATAATGTGTTTTGCTTGAATAAAATGTTACATTTATACTTTGAGAACTCTGACCAAATCTTTCATACAGATAC
AGGTAAAGAAATATTTTTCTAGGTTGTCGGAGCTGCGTACCTCCCGCTGCTTCTCCTTGTGGTCCAGCACCACCTGCTGGTCAGTGGCAG
AACTGTCCTGACTTCGTGAACATGGAACTGCTAAGAGGGAAAACTGCATCTCAGCATTTTCATTTTTTCTGAATATTAAGTGAAAAGCAA
GTTCTATTTTTAAGAAATAGCTTTTGCTGAGGAGTTGTGAATTCCTGCACCTGTGTTTGATGTTATTTGTATGCAATGGATTGCTGGCCC
TTTGTTCCTAAGCAAGAGAAGACCAAAGATGCTTCCCCATGACCTCTCCGGTGAGGATCCGCACCCCCCGGACTTGCTCTCTGATGAAGG
GCATGTCGTTCAGTGCCCCAGCAGTCAGAAGCAGTTTTTGTGGAACTAAAACTAATAATGTTACCCTCACAAAGGAAATGTTCTTTTACT
AAGTTATTGCTGATTCTTGAATGTCTGTTATATAACTGGGTCGGCTATCAAGAAGGAAGGTTATATTTCTTATCACATTTTAAGTTGTTA
AGCAAATGTGAGTTTTTTTTTAAGAAATGAGGCTTTCACTGAGATTTGTGTGCTATTCATAATTTTAGGAATTACTGCTTAGAACAGCTG
CTTGGGTGTATTTTTCTACACAGGTCTGTACTTCTGCCACTTTCTCCTTTTAAAAAAACAAAACTATGCATATTATGTATTAAAGTTTTC

>12445_12445_7_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000537058_PARD6G_chr18_77960815_ENST00000353265_length(amino acids)=343AA_BP=
MDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRD
EGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN
DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVI

--------------------------------------------------------------
>12445_12445_8_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000537058_PARD6G_chr18_77960815_ENST00000470488_length(transcript)=669nt_BP=145nt
AGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCGGCGGCGGCGCCTCCCGGG
CTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCGAAGGTTCTCTCTGGACCG
TCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGTAACTATTGGCTATGCAGA
TGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCTGCTCAGGGTCTTCATCCA
GAAACGAGATGACGGAGCCCTGCGACCAGGAACCTGACTCTTCAGCTCAAATCTTGGTTTGAAAGGGGGACTTCTCTGTGCCCCTGTTGT
CGGCATGCCATGGTAGAGAATGGATGGCCCACGCAGCTGGCCCCTCATGAGACCCCAGCCATCTCATTCCACTGGGAGCCACGTCAGGAC
GAAGGAGGACTGGGAGGGGCGTCTGGCTGCGTGGTGTGGGGCCTGCAGTGTTGTGGCACACGCAGCTTCAGCCAAACATCTAGCCCTGTA

>12445_12445_8_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000537058_PARD6G_chr18_77960815_ENST00000470488_length(amino acids)=84AA_BP=

--------------------------------------------------------------
>12445_12445_9_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000542447_PARD6G_chr18_77960815_ENST00000353265_length(transcript)=3851nt_BP=253nt
GGTTGGGCTCGCGGCGCTGTGATTGGTCTGCCCGGACTCCGCCTCCAGCGCATGTCATTAGCATCTCATTAGCTGTCCGCTCGGGCTCCG
GAGGCAGCCAACGCCGCCAGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCG
GCGGCGGCGCCTCCCGGGCTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCG
AAGGTTCTCTCTGGACCGTCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGT
AACTATTGGCTATGCAGATGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCT
GCTCAGGGTCTTCATCCAGAAACGAGAGGAGGCCGAGCGTGGCAGCCTCGGCGCGGGCTCGCTGTGCAGGCGGAGGCGGGCGCTGGGCGC
GCTGCGTGATGAAGGACCCCGGCGGCGTGCACACCTGGACATCGGCCTCCCGCGCGACTTCCGCCCCGTATCATCCATCATCGATGTGGA
CCTGGTCCCCGAGACGCACCGGCGAGTGCGGCTGCACCGGCACGGCTGCGAGAAGCCGCTGGGCTTCTACATCCGCGATGGCGCCAGCGT
GCGCGTGACCCCGCACGGGCTGGAGAAGGTGCCCGGCATCTTCATCTCGCGCATGGTACCCGGGGGCCTGGCGGAGAGCACCGGGCTGCT
GGCTGTGAATGACGAGGTCCTGGAGGTGAACGGCATTGAGGTGGCCGGGAAGACGCTGGACCAGGTCACGGACATGATGATCGCCAACAG
CCACAACCTCATCGTCACCGTCAAGCCCGCCAACCAGCGCAACAACGTGGTGCGCGGCGGCCGCGCGTTGGGCAGCTCGGGACCGCCCTC
GGACGGCACCGCGGGCTTCGTGGGTCCCCCCGCCCCGCGCGTCCTGCAGAACTTCCACCCCGACGAGGCGGAGAGCGATGAGGACAACGA
CGTCGTCATCGAGGGCACACTGGAGCCTGCACGTCCCCCCCAGACCCCGGGCGCGCCCGCAGGCAGCCTCTCCCGGGTCAATGGCGCGGG
CCTGGCGCAGCGGCTGCAGCGGGACCTGGCCCTGGACGGCGGCCTCCAGCGGCTGCTCAGCTCCCTGCGGGCCGACCCCCGTCACAGCCT
GGCGCTGCCGCCAGGCGGCGTGGAGGAGCACGGGCCCGCGGTCACGCTCTAGACTCCCGAGAGGCCCCCAAATCCTAGCTCCAGTTCCCC
GGTAAGGACAGGGACAGGACCTGCAGACTGCATCCGCTCATTTTTTGTTGTTTTTGTGACCACAAAAACAACGCTGCTCTTTGTTTCAAC
TTCCGGATATAAAAACACAAGTATTGCCTATTTTTATAGAATTTCGCCACAGAACTTAAAATGAACGCCTGTAGAGACACTCTATACCAG
GCCTGAGTGCAGGTCTTGGCGCCTTTGCAAAGTGATAGAAAAGATCTGACCAAGTGCAAAAAAATGCTTTTTAAAATTTTTACAAATACT
TTGTTTTTAAAGTGAAGCTTTAAAATTACTTTTTTAAAATAGTCAAATTCATGTTTTTAAGTAAGTTGGCCCATGCAACATATCTCAGCA
TTCTTGCTGTGCTCTCTGCTGACTTGCAGGCGAGGCCGACTGTGCTGATGTACGTGACAAGAGGCTGGTTTTTAATAACGAATGCAGCCA
GGTGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCTACGTGGGCTGATCACGAGGTCAGGAGGTCGAGACCAGCATGGCCAA
CATGGTGAAACCCTGTCTCTACTAAAAATATAAAAATTAGCCAGGTGTGGTGGCAGGCGCCTGTAATCCCAGCTACCTTGGGAGGCTGAG
GCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTC
TGTCTCGGGAAAAAAAAAAAATACACCCAAACCTGTCCATGTACAACCATGGAGATGAATTCCAGATTTTCACACTGTTCATAGTCATAA
TTCGGTTGGGACAGGAGAGCTCCCACCAGCACACTTATGGCACCCGCAGCTGTGGAATTGTTCCGGGGCTTTTTTTTGTTTGTTTTGAGA
CATAGTGTCTTGTTCTGTCATCCAAGCTGGAGGGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGC
CTCCCAAGGAGCTGGGACAGGCACATGCCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCACCACGTTGGTCAGGC
TGGTCTTGAACTCCTGACCTCAGGTGATACGGTCCCCCCTCAGCCTCCAAAAATGCTAGGATTATAGACGTGAGCCACAGCACCAGACCA
GGGGCTATTTTTGTGACCCACATAGGTGGCCCATTCAGCCTCAAGGGGAAATCCAGGGTAGGAAGCAGCAGCTCTGCTGGACTGGGCTCA
GCAGTCCCATTTGGGATGTAAGCCTCTATTGCCTCTAAGATGACCCTTTTCCTGTGGGTTGACTGACTCTGAGGGCGATTTCGGAAATGT
TTTCAGCAGAAATGAAGGATAAGCATCGCACATGTCCAGCAATGTCTTTGAGAATGCAGTCATTTGCACGTGAGTTCTCATCTTTGTTTT
CTGAAACAGACGTTTCTTTTAGTAAGTCACAATACATGCTAATTTTCATTTCTAGAATGGTCACTGGCAGTTCTCACTTTTAACTATAAG
AAGTCACGTGGAACTTAGTGATTTTTAACAAATACTAAATTCATCCTCACTTTATGTTGATCTTCCAGCAACGTTTATATATTTAGTAAT
TTTAAAAATTCCTATTTGATACAATTAAATTTTATATAATGTGTTTTGCTTGAATAAAATGTTACATTTATACTTTGAGAACTCTGACCA
AATCTTTCATACAGATACAGGTAAAGAAATATTTTTCTAGGTTGTCGGAGCTGCGTACCTCCCGCTGCTTCTCCTTGTGGTCCAGCACCA
CCTGCTGGTCAGTGGCAGAACTGTCCTGACTTCGTGAACATGGAACTGCTAAGAGGGAAAACTGCATCTCAGCATTTTCATTTTTTCTGA
ATATTAAGTGAAAAGCAAGTTCTATTTTTAAGAAATAGCTTTTGCTGAGGAGTTGTGAATTCCTGCACCTGTGTTTGATGTTATTTGTAT
GCAATGGATTGCTGGCCCTTTGTTCCTAAGCAAGAGAAGACCAAAGATGCTTCCCCATGACCTCTCCGGTGAGGATCCGCACCCCCCGGA
CTTGCTCTCTGATGAAGGGCATGTCGTTCAGTGCCCCAGCAGTCAGAAGCAGTTTTTGTGGAACTAAAACTAATAATGTTACCCTCACAA
AGGAAATGTTCTTTTACTAAGTTATTGCTGATTCTTGAATGTCTGTTATATAACTGGGTCGGCTATCAAGAAGGAAGGTTATATTTCTTA
TCACATTTTAAGTTGTTAAGCAAATGTGAGTTTTTTTTTAAGAAATGAGGCTTTCACTGAGATTTGTGTGCTATTCATAATTTTAGGAAT
TACTGCTTAGAACAGCTGCTTGGGTGTATTTTTCTACACAGGTCTGTACTTCTGCCACTTTCTCCTTTTAAAAAAACAAAACTATGCATA

>12445_12445_9_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000542447_PARD6G_chr18_77960815_ENST00000353265_length(amino acids)=343AA_BP=
MDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDDNFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRALGALRD
EGPRRRAHLDIGLPRDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN
DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVI

--------------------------------------------------------------
>12445_12445_10_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000542447_PARD6G_chr18_77960815_ENST00000470488_length(transcript)=777nt_BP=253nt
GGTTGGGCTCGCGGCGCTGTGATTGGTCTGCCCGGACTCCGCCTCCAGCGCATGTCATTAGCATCTCATTAGCTGTCCGCTCGGGCTCCG
GAGGCAGCCAACGCCGCCAGTCTGAGGCAGGTGCCCGACATGGCGAGTGTAGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCG
GCGGCGGCGCCTCCCGGGCTCCGGCTCCGGCTTCTGCTGTTGCTCTTCTCCGCCGCGGCACTGATCCCCACAGTTTGGGGCGGAATTCCG
AAGGTTCTCTCTGGACCGTCATAAGCCTGGGAAGTTTGAAGATTTCTACAAGCTGGTTGTGCACACCCACCATATCTCCAACAGTGATGT
AACTATTGGCTATGCAGATGTGCACGGAGACCTGCTGCCCATCAACAATGATGACAACTTCTGCAAGGCGGTTTCTAGTGCAAATCCCCT
GCTCAGGGTCTTCATCCAGAAACGAGATGACGGAGCCCTGCGACCAGGAACCTGACTCTTCAGCTCAAATCTTGGTTTGAAAGGGGGACT
TCTCTGTGCCCCTGTTGTCGGCATGCCATGGTAGAGAATGGATGGCCCACGCAGCTGGCCCCTCATGAGACCCCAGCCATCTCATTCCAC
TGGGAGCCACGTCAGGACGAAGGAGGACTGGGAGGGGCGTCTGGCTGCGTGGTGTGGGGCCTGCAGTGTTGTGGCACACGCAGCTTCAGC

>12445_12445_10_CADM1-PARD6G_CADM1_chr11_115374988_ENST00000542447_PARD6G_chr18_77960815_ENST00000470488_length(amino acids)=119AA_BP=83
LGSRRCDWSARTPPPAHVISISLAVRSGSGGSQRRQSEAGARHGECSAAERIPVCGGSGGGGASRAPAPASAVALLRRGTDPHSLGRNSE

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Fusion Gene PPI Analysis for CADM1-PARD6G


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePARD6Gchr11:115374988chr18:77960815ENST0000035326503127_25424.0377.0PARD3 and CDC42
TgenePARD6Gchr11:115374988chr18:77960815ENST0000047048803127_25424.0108.0PARD3 and CDC42


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CADM1-PARD6G


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CADM1-PARD6G


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource