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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CADPS2-XRCC6BP1 (FusionGDB2 ID:12480)

Fusion Gene Summary for CADPS2-XRCC6BP1

check button Fusion gene summary
Fusion gene informationFusion gene name: CADPS2-XRCC6BP1
Fusion gene ID: 12480
HgeneTgene
Gene symbol

CADPS2

XRCC6BP1

Gene ID

93664

91419

Gene namecalcium dependent secretion activator 2ATP23 metallopeptidase and ATP synthase assembly factor homolog
SynonymsCAPS2KUB3|XRCC6BP1
Cytomap

7q31.32

12q14.1

Type of geneprotein-codingprotein-coding
Descriptioncalcium-dependent secretion activator 2CAPS-2Ca++-dependent secretion activator 2Ca2+ dependent secretion activator 2Ca2+-dependent activator protein for secretion 2calcium-dependent activator protein for secretion 2mitochondrial inner membrane protease ATP23 homologKu70-binding protein 3XRCC6-binding protein 1
Modification date2020031320200320
UniProtAcc

Q86UW7

.
Ensembl transtripts involved in fusion geneENST00000313070, ENST00000334010, 
ENST00000412584, ENST00000449022, 
ENST00000476131, 		ENST00000546709, 
ENST00000300145, 
Fusion gene scores* DoF score12 X 11 X 7=92418 X 7 X 5=630
# samples 1421
** MAII scorelog2(14/924*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/630*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CADPS2 [Title/Abstract] AND XRCC6BP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCADPS2(122526052)-XRCC6BP1(58345540), # samples:2
Anticipated loss of major functional domain due to fusion event.CADPS2-XRCC6BP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CADPS2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across XRCC6BP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A6BH-01ACADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
ChimerDB4SARCTCGA-DX-A6BH-01ACADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
ChimerDB4SARCTCGA-DX-A6BH-01ACADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
ChimerDB4SARCTCGA-DX-A6BH-01ACADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
ChimerDB4SARCTCGA-DX-A6BHCADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+


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Fusion Gene ORF analysis for CADPS2-XRCC6BP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000313070ENST00000546709CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
5CDS-3UTRENST00000313070ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
5CDS-3UTRENST00000334010ENST00000546709CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
5CDS-3UTRENST00000334010ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
5CDS-3UTRENST00000412584ENST00000546709CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
5CDS-3UTRENST00000412584ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
5CDS-3UTRENST00000449022ENST00000546709CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
5CDS-3UTRENST00000449022ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
5CDS-intronENST00000313070ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
5CDS-intronENST00000334010ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
5CDS-intronENST00000412584ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
5CDS-intronENST00000449022ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
Frame-shiftENST00000313070ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
Frame-shiftENST00000334010ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
Frame-shiftENST00000412584ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
Frame-shiftENST00000449022ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
In-frameENST00000313070ENST00000300145CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
In-frameENST00000313070ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
In-frameENST00000334010ENST00000300145CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
In-frameENST00000334010ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
In-frameENST00000412584ENST00000300145CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
In-frameENST00000412584ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
In-frameENST00000449022ENST00000300145CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
In-frameENST00000449022ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
intron-3CDSENST00000313070ENST00000300145CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000334010ENST00000300145CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000412584ENST00000300145CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000449022ENST00000300145CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000476131ENST00000300145CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000476131ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+
intron-3CDSENST00000476131ENST00000300145CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
intron-3CDSENST00000476131ENST00000300145CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
intron-3UTRENST00000476131ENST00000546709CADPS2chr7

122526053

-XRCC6BP1chr12

58345541

+
intron-3UTRENST00000476131ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58345540

+
intron-intronENST00000313070ENST00000546709CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-intronENST00000334010ENST00000546709CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-intronENST00000412584ENST00000546709CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-intronENST00000449022ENST00000546709CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-intronENST00000476131ENST00000546709CADPS2chr7

122525447

-XRCC6BP1chr12

58339410

+
intron-intronENST00000476131ENST00000546709CADPS2chr7

122526052

-XRCC6BP1chr12

58339410

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313070CADPS2chr7122526052-ENST00000300145XRCC6BP1chr1258345540+15667614221186254
ENST00000334010CADPS2chr7122526052-ENST00000300145XRCC6BP1chr1258345540+15667614221186254
ENST00000412584CADPS2chr7122526052-ENST00000300145XRCC6BP1chr1258345540+1265460121885254
ENST00000449022CADPS2chr7122526052-ENST00000300145XRCC6BP1chr1258345540+116435920784254
ENST00000313070CADPS2chr7122526053-ENST00000300145XRCC6BP1chr1258345541+15667614221186254
ENST00000334010CADPS2chr7122526053-ENST00000300145XRCC6BP1chr1258345541+15667614221186254
ENST00000412584CADPS2chr7122526053-ENST00000300145XRCC6BP1chr1258345541+1265460121885254
ENST00000449022CADPS2chr7122526053-ENST00000300145XRCC6BP1chr1258345541+116435920784254

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313070ENST00000300145CADPS2chr7122526052-XRCC6BP1chr1258345540+0.003888710.99611133
ENST00000334010ENST00000300145CADPS2chr7122526052-XRCC6BP1chr1258345540+0.003888710.99611133
ENST00000412584ENST00000300145CADPS2chr7122526052-XRCC6BP1chr1258345540+0.0026828120.99731714
ENST00000449022ENST00000300145CADPS2chr7122526052-XRCC6BP1chr1258345540+0.0020635930.9979365
ENST00000313070ENST00000300145CADPS2chr7122526053-XRCC6BP1chr1258345541+0.003888710.99611133
ENST00000334010ENST00000300145CADPS2chr7122526053-XRCC6BP1chr1258345541+0.003888710.99611133
ENST00000412584ENST00000300145CADPS2chr7122526053-XRCC6BP1chr1258345541+0.0026828120.99731714
ENST00000449022ENST00000300145CADPS2chr7122526053-XRCC6BP1chr1258345541+0.0020635930.9979365

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Fusion Genomic Features for CADPS2-XRCC6BP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CADPS2chr7122526052-XRCC6BP1chr1258345544+2.24E-091
CADPS2chr7122526052-XRCC6BP1chr1258345544+2.24E-091
CADPS2chr7122526052-XRCC6BP1chr1258339410+1.80E-081
CADPS2chr7122526052-XRCC6BP1chr1258345544+2.24E-091
CADPS2chr7122526052-XRCC6BP1chr1258345544+2.24E-091
CADPS2chr7122526052-XRCC6BP1chr1258339410+1.80E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CADPS2-XRCC6BP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:122526052/chr12:58345540)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CADPS2

Q86UW7

.
FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCADPS2chr7:122526052chr12:58345540ENST00000412584-128350_4641131256.0DomainC2
HgeneCADPS2chr7:122526052chr12:58345540ENST00000412584-128487_5901131256.0DomainPH
HgeneCADPS2chr7:122526052chr12:58345540ENST00000412584-128885_10561131256.0DomainMHD1
HgeneCADPS2chr7:122526052chr12:58345540ENST00000449022-130350_4641131297.0DomainC2
HgeneCADPS2chr7:122526052chr12:58345540ENST00000449022-130487_5901131297.0DomainPH
HgeneCADPS2chr7:122526052chr12:58345540ENST00000449022-130885_10561131297.0DomainMHD1
HgeneCADPS2chr7:122526053chr12:58345541ENST00000412584-128350_4641131256.0DomainC2
HgeneCADPS2chr7:122526053chr12:58345541ENST00000412584-128487_5901131256.0DomainPH
HgeneCADPS2chr7:122526053chr12:58345541ENST00000412584-128885_10561131256.0DomainMHD1
HgeneCADPS2chr7:122526053chr12:58345541ENST00000449022-130350_4641131297.0DomainC2
HgeneCADPS2chr7:122526053chr12:58345541ENST00000449022-130487_5901131297.0DomainPH
HgeneCADPS2chr7:122526053chr12:58345541ENST00000449022-130885_10561131297.0DomainMHD1


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Fusion Gene Sequence for CADPS2-XRCC6BP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12480_12480_1_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000313070_XRCC6BP1_chr12_58345540_ENST00000300145_length(transcript)=1566nt_BP=761nt
ATTCAATTCCACGTGTTGCTTGTTGTAGGCGCCACAGGTTCCCCACCTGCGTCCGGGCGCTCGGGCGGCTCCGCCTCTGCCGGCGGGCTC
TGGGGAACCGCTGGGTCGGCGCGCCCGGGGCTGGCGGAGCAATTCCTGAGGCGCCCAAGCTCACCCCCAACGCTAACTCCGCCTATTCAG
TCCCGGCGGCTCCCCCTCTCCCCCCTCCCAATCCTCCTCCCGGCTCCTGCCCGCCCCTTTCGCCCTGGTGGTAGGAAACACTCCTGAATC
TAACTCGACGTGTCCGGAAAGCCCTGGCCAGTTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGC
GCAGCCGCCGGGGGTGAGGCGCTTGGGGACCGCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGG
AGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAG
GGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACG
AGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCA
ACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAG
TGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGG
TTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTG
TGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTT
GTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGT
ATTATTCAAATATATGAGCACAATGACATTTTTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAA
ACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAA
AAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGT
CATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGT

>12480_12480_1_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000313070_XRCC6BP1_chr12_58345540_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_2_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000334010_XRCC6BP1_chr12_58345540_ENST00000300145_length(transcript)=1566nt_BP=761nt
ATTCAATTCCACGTGTTGCTTGTTGTAGGCGCCACAGGTTCCCCACCTGCGTCCGGGCGCTCGGGCGGCTCCGCCTCTGCCGGCGGGCTC
TGGGGAACCGCTGGGTCGGCGCGCCCGGGGCTGGCGGAGCAATTCCTGAGGCGCCCAAGCTCACCCCCAACGCTAACTCCGCCTATTCAG
TCCCGGCGGCTCCCCCTCTCCCCCCTCCCAATCCTCCTCCCGGCTCCTGCCCGCCCCTTTCGCCCTGGTGGTAGGAAACACTCCTGAATC
TAACTCGACGTGTCCGGAAAGCCCTGGCCAGTTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGC
GCAGCCGCCGGGGGTGAGGCGCTTGGGGACCGCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGG
AGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAG
GGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACG
AGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCA
ACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAG
TGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGG
TTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTG
TGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTT
GTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGT
ATTATTCAAATATATGAGCACAATGACATTTTTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAA
ACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAA
AAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGT
CATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGT

>12480_12480_2_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000334010_XRCC6BP1_chr12_58345540_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_3_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000412584_XRCC6BP1_chr12_58345540_ENST00000300145_length(transcript)=1265nt_BP=460nt
TTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGCGCAGCCGCCGGGGGTGAGGCGCTTGGGGACC
GCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGGAGTCGGACGAGGGGCTGGAAGAGGAAAGCCG
CGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAGGGCGGCGGGACGCGCCGGGGCGCGCGGGCGG
CGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACGAGCCCCAGCGGCAGCTGGACGATGAGCAGGA
GCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCAACGCCAAGCAGCCCACCGACATGGCCCGGAG
GCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAGTGGTCACACACGAGCTTATTCATGCATTTGA
TCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGGTTCGAGCTGCTAACCTTAGTGGAGACTGCTC
ACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTGTGCGAGACAGAGCCACTCTTTCTATCCTGGC
TGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTTGTTTCAATGACCATGAACCTTTTGGAAGGAT
CCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGTATTATTCAAATATATGAGCACAATGACATTT
TTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAAACATATAAAATGTAAACAATCCCTACAATCC
AGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAAAAATGAAACTGCTTTAAACTCCAAGGCAGAA
ATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGTCATTTGTTTTTATTACATGTGATTATTTTAA
AATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGTTGGTATTTACATTAAATGTAAAGAAATGTGT

>12480_12480_3_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000412584_XRCC6BP1_chr12_58345540_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_4_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000449022_XRCC6BP1_chr12_58345540_ENST00000300145_length(transcript)=1164nt_BP=359nt
GGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGGAGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGG
TGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAGGGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGG
CCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACGAGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCC
GCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCAACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGA
TAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAGTGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTG
CCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGGTTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATG
AAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTGTGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATA
TCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTTGTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACA
AGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGTATTATTCAAATATATGAGCACAATGACATTTTTATATTACAG
AGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAAACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAG
AGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAAAAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTT
ATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGTCATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTAT

>12480_12480_4_CADPS2-XRCC6BP1_CADPS2_chr7_122526052_ENST00000449022_XRCC6BP1_chr12_58345540_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_5_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000313070_XRCC6BP1_chr12_58345541_ENST00000300145_length(transcript)=1566nt_BP=761nt
ATTCAATTCCACGTGTTGCTTGTTGTAGGCGCCACAGGTTCCCCACCTGCGTCCGGGCGCTCGGGCGGCTCCGCCTCTGCCGGCGGGCTC
TGGGGAACCGCTGGGTCGGCGCGCCCGGGGCTGGCGGAGCAATTCCTGAGGCGCCCAAGCTCACCCCCAACGCTAACTCCGCCTATTCAG
TCCCGGCGGCTCCCCCTCTCCCCCCTCCCAATCCTCCTCCCGGCTCCTGCCCGCCCCTTTCGCCCTGGTGGTAGGAAACACTCCTGAATC
TAACTCGACGTGTCCGGAAAGCCCTGGCCAGTTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGC
GCAGCCGCCGGGGGTGAGGCGCTTGGGGACCGCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGG
AGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAG
GGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACG
AGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCA
ACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAG
TGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGG
TTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTG
TGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTT
GTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGT
ATTATTCAAATATATGAGCACAATGACATTTTTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAA
ACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAA
AAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGT
CATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGT

>12480_12480_5_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000313070_XRCC6BP1_chr12_58345541_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_6_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000334010_XRCC6BP1_chr12_58345541_ENST00000300145_length(transcript)=1566nt_BP=761nt
ATTCAATTCCACGTGTTGCTTGTTGTAGGCGCCACAGGTTCCCCACCTGCGTCCGGGCGCTCGGGCGGCTCCGCCTCTGCCGGCGGGCTC
TGGGGAACCGCTGGGTCGGCGCGCCCGGGGCTGGCGGAGCAATTCCTGAGGCGCCCAAGCTCACCCCCAACGCTAACTCCGCCTATTCAG
TCCCGGCGGCTCCCCCTCTCCCCCCTCCCAATCCTCCTCCCGGCTCCTGCCCGCCCCTTTCGCCCTGGTGGTAGGAAACACTCCTGAATC
TAACTCGACGTGTCCGGAAAGCCCTGGCCAGTTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGC
GCAGCCGCCGGGGGTGAGGCGCTTGGGGACCGCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGG
AGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAG
GGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACG
AGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCA
ACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAG
TGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGG
TTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTG
TGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTT
GTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGT
ATTATTCAAATATATGAGCACAATGACATTTTTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAA
ACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAA
AAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGT
CATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGT

>12480_12480_6_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000334010_XRCC6BP1_chr12_58345541_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_7_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000412584_XRCC6BP1_chr12_58345541_ENST00000300145_length(transcript)=1265nt_BP=460nt
TTTTCCTTTCGTTCTGCGGCCGCTGCAGCCAGCCCCGCGGCTCCCTCAGACCCGCGGGCGCAGCCGCCGGGGGTGAGGCGCTTGGGGACC
GCGGGCCGAGCGGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGGAGTCGGACGAGGGGCTGGAAGAGGAAAGCCG
CGATGTGCTGGTGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAGGGCGGCGGGACGCGCCGGGGCGCGCGGGCGG
CGGCGGCGCGGCCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACGAGCCCCAGCGGCAGCTGGACGATGAGCAGGA
GCGGAGGATCCGCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCAACGCCAAGCAGCCCACCGACATGGCCCGGAG
GCAGCAGAAGATAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAGTGGTCACACACGAGCTTATTCATGCATTTGA
TCATTGTCGTGCCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGGTTCGAGCTGCTAACCTTAGTGGAGACTGCTC
ACTTGTCAATGAAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTGTGCGAGACAGAGCCACTCTTTCTATCCTGGC
TGTTAGGAATATCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTTGTTTCAATGACCATGAACCTTTTGGAAGGAT
CCCACATAACAAGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGTATTATTCAAATATATGAGCACAATGACATTT
TTATATTACAGAGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAAACATATAAAATGTAAACAATCCCTACAATCC
AGATAAAACAGAGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAAAAATGAAACTGCTTTAAACTCCAAGGCAGAA
ATTGTATCTTTATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGTCATTTGTTTTTATTACATGTGATTATTTTAA
AATTTGATTATGAAACCTGTGAAGTGTGCTCTTCCATGATGTTGATAGGTGACCACTGTTGGTATTTACATTAAATGTAAAGAAATGTGT

>12480_12480_7_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000412584_XRCC6BP1_chr12_58345541_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------
>12480_12480_8_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000449022_XRCC6BP1_chr12_58345541_ENST00000300145_length(transcript)=1164nt_BP=359nt
GGCGGGGATCCCCGAGCACCATGCTGGACCCGTCTTCCAGCGAAGAGGAGTCGGACGAGGGGCTGGAAGAGGAAAGCCGCGATGTGCTGG
TGGCAGCCGGCAGCTCGCAGCGAGCTCCTCCAGCCCCGACTCGGGAAGGGCGGCGGGACGCGCCGGGGCGCGCGGGCGGCGGCGGCGCGG
CCAGATCTGTGAGCCCGAGCCCCTCTGTGCTCAGCGAGGGGCGAGACGAGCCCCAGCGGCAGCTGGACGATGAGCAGGAGCGGAGGATCC
GCCTGCAGCTCTACGTCTTCGTCGTGAGGTGCATCGCGTACCCCTTCAACGCCAAGCAGCCCACCGACATGGCCCGGAGGCAGCAGAAGA
TAGTTTTGTGCCAGAATAATATCCATAATCAGGCCCATATGAACAGAGTGGTCACACACGAGCTTATTCATGCATTTGATCATTGTCGTG
CCCATGTCGACTGGTTCACCAACATCAGACATTTGGCGTGCTCAGAGGTTCGAGCTGCTAACCTTAGTGGAGACTGCTCACTTGTCAATG
AAATATTCAGGTTACATTTTGGATTAAAACAACACCACCAGACTTGTGTGCGAGACAGAGCCACTCTTTCTATCCTGGCTGTTAGGAATA
TCAGCAAAGAAGTAGCTAAAAAGGCTGTTGATGAAGTTTTTGAATCTTGTTTCAATGACCATGAACCTTTTGGAAGGATCCCACATAACA
AGACTTATGCAAGATATGCTCACAGAGACTTTGAAAACCGTGATCGGTATTATTCAAATATATGAGCACAATGACATTTTTATATTACAG
AGCTTCCATCATCATGAAGAAAAAAAAATTTGGTTCTCAAGTGAACAAACATATAAAATGTAAACAATCCCTACAATCCAGATAAAACAG
AGAAGACTGTGATTCTAGCATATTATCAGAAAAAGTAACTATGGCAAAAAATGAAACTGCTTTAAACTCCAAGGCAGAAATTGTATCTTT
ATAGCTAACCATTTAGTAAATAAATACATTACATTTTTGTATTTTAGTCATTTGTTTTTATTACATGTGATTATTTTAAAATTTGATTAT

>12480_12480_8_CADPS2-XRCC6BP1_CADPS2_chr7_122526053_ENST00000449022_XRCC6BP1_chr12_58345541_ENST00000300145_length(amino acids)=254AA_BP=113
MLDPSSSEEESDEGLEEESRDVLVAAGSSQRAPPAPTREGRRDAPGRAGGGGAARSVSPSPSVLSEGRDEPQRQLDDEQERRIRLQLYVF
VVRCIAYPFNAKQPTDMARRQQKIVLCQNNIHNQAHMNRVVTHELIHAFDHCRAHVDWFTNIRHLACSEVRAANLSGDCSLVNEIFRLHF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CADPS2-XRCC6BP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCADPS2chr7:122526052chr12:58345540ENST00000412584-128755_1074113.01256.0DRD2
HgeneCADPS2chr7:122526052chr12:58345540ENST00000449022-130755_1074113.01297.0DRD2
HgeneCADPS2chr7:122526053chr12:58345541ENST00000412584-128755_1074113.01256.0DRD2
HgeneCADPS2chr7:122526053chr12:58345541ENST00000449022-130755_1074113.01297.0DRD2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CADPS2-XRCC6BP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CADPS2-XRCC6BP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource