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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAPNS1-ARHGEF26 (FusionGDB2 ID:12904)

Fusion Gene Summary for CAPNS1-ARHGEF26

check button Fusion gene summary
Fusion gene informationFusion gene name: CAPNS1-ARHGEF26
Fusion gene ID: 12904
HgeneTgene
Gene symbol

CAPNS1

ARHGEF26

Gene ID

826

26084

Gene namecalpain small subunit 1Rho guanine nucleotide exchange factor 26
SynonymsCALPAIN4|CANP|CANPS|CAPN4|CDPS|CSS1CSGEF|HMFN1864|SGEF
Cytomap

19q13.12

3q25.2

Type of geneprotein-codingprotein-coding
Descriptioncalpain small subunit 1CANP small subunitcalcium-activated neutral proteinase small subunitcalcium-dependent protease small subunit 1calcium-dependent protease, small subunitcalpain 4, small subunit (30K)calpain regulatory subunitcalpain, small polrho guanine nucleotide exchange factor 26Rho guanine nucleotide exchange factor (GEF) 26SH3 domain-containing guanine exchange factorSrc homology 3 domain-containing guanine nucleotide exchange factortesticular tissue protein Li 171
Modification date2020031320200313
UniProtAcc

P04632

Q96DR7

Ensembl transtripts involved in fusion geneENST00000246533, ENST00000587718, 
ENST00000588815, ENST00000588780, 
ENST00000589146, ENST00000590874, 
ENST00000483068, ENST00000356448, 
ENST00000465093, ENST00000465817, 
Fusion gene scores* DoF score29 X 25 X 9=65256 X 5 X 4=120
# samples 316
** MAII scorelog2(31/6525*10)=-4.39563778107037
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAPNS1 [Title/Abstract] AND ARHGEF26 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAPNS1(36641254)-ARHGEF26(153842199), # samples:1
Anticipated loss of major functional domain due to fusion event.CAPNS1-ARHGEF26 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CAPNS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGEF26 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6371-01ACAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+


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Fusion Gene ORF analysis for CAPNS1-ARHGEF26

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000246533ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
5CDS-intronENST00000587718ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
5CDS-intronENST00000588815ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
Frame-shiftENST00000587718ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
Frame-shiftENST00000587718ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
Frame-shiftENST00000587718ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000246533ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000246533ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000246533ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000588815ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000588815ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
In-frameENST00000588815ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000588780ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000588780ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000588780ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000589146ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000589146ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000589146ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000590874ENST00000356448CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000590874ENST00000465093CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-3CDSENST00000590874ENST00000465817CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-intronENST00000588780ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-intronENST00000589146ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+
intron-intronENST00000590874ENST00000483068CAPNS1chr19

36641254

-ARHGEF26chr3

153842199

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000246533CAPNS1chr1936641254-ENST00000356448ARHGEF26chr3153842199+5805191818613450529
ENST00000246533CAPNS1chr1936641254-ENST00000465093ARHGEF26chr3153842199+4553191818613450529
ENST00000246533CAPNS1chr1936641254-ENST00000465817ARHGEF26chr3153842199+305719185981404268
ENST00000588815CAPNS1chr1936641254-ENST00000356448ARHGEF26chr3153842199+5358147114143003529
ENST00000588815CAPNS1chr1936641254-ENST00000465093ARHGEF26chr3153842199+4106147114143003529
ENST00000588815CAPNS1chr1936641254-ENST00000465817ARHGEF26chr3153842199+26101471151957268

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000246533ENST00000356448CAPNS1chr1936641254-ARHGEF26chr3153842199+0.0003522010.99964774
ENST00000246533ENST00000465093CAPNS1chr1936641254-ARHGEF26chr3153842199+0.0006579930.999342
ENST00000246533ENST00000465817CAPNS1chr1936641254-ARHGEF26chr3153842199+0.0010158040.99898416
ENST00000588815ENST00000356448CAPNS1chr1936641254-ARHGEF26chr3153842199+0.0003145710.9996854
ENST00000588815ENST00000465093CAPNS1chr1936641254-ARHGEF26chr3153842199+0.00056620.9994338
ENST00000588815ENST00000465817CAPNS1chr1936641254-ARHGEF26chr3153842199+0.000774620.9992254

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Fusion Genomic Features for CAPNS1-ARHGEF26


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CAPNS1-ARHGEF26


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:36641254/chr3:153842199)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CAPNS1

P04632

ARHGEF26

Q96DR7

FUNCTION: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.FUNCTION: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. {ECO:0000269|PubMed:15133129, ECO:0000269|PubMed:17074883, ECO:0000269|PubMed:17875742}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111108_119440269.0Calcium binding1
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111152_163440269.0Calcium binding2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111182_193440269.0Calcium binding3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010108_119497323.0Calcium binding1
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010152_163497323.0Calcium binding2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010182_193497323.0Calcium binding3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111108_119440269.0Calcium binding1
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111152_163440269.0Calcium binding2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111182_193440269.0Calcium binding3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-111110_26440269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-11111_66440269.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-111135_56440269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-111178_83440269.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-101010_26497323.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-10101_66497323.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-101035_56497323.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-101078_83497323.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-111110_26440269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-11111_66440269.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-111135_56440269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-111178_83440269.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111139_172440269.0DomainEF-hand 2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111169_204440269.0DomainEF-hand 3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111205_233440269.0DomainEF-hand 4
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-1111234_268440269.0DomainEF-hand 5
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000246533-111191_125440269.0DomainEF-hand 1%3B atypical
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010139_172497323.0DomainEF-hand 2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010169_204497323.0DomainEF-hand 3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010205_233497323.0DomainEF-hand 4
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-1010234_268497323.0DomainEF-hand 5
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000587718-101091_125497323.0DomainEF-hand 1%3B atypical
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111139_172440269.0DomainEF-hand 2
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111169_204440269.0DomainEF-hand 3
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111205_233440269.0DomainEF-hand 4
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-1111234_268440269.0DomainEF-hand 5
HgeneCAPNS1chr19:36641254chr3:153842199ENST00000588815-111191_125440269.0DomainEF-hand 1%3B atypical
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000356448115439_623361872.0DomainDH
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000356448115655_782361872.0DomainPH
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000356448115789_850361872.0DomainSH3
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000465093115439_623361872.0DomainDH
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000465093115655_782361872.0DomainPH
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000465093115789_850361872.0DomainSH3
TgeneARHGEF26chr19:36641254chr3:153842199ENST0000046581715439_623361447.0DomainDH
TgeneARHGEF26chr19:36641254chr3:153842199ENST0000046581715655_782361447.0DomainPH
TgeneARHGEF26chr19:36641254chr3:153842199ENST0000046581715789_850361447.0DomainSH3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000356448115106_173361872.0Compositional biasNote=Pro-rich
TgeneARHGEF26chr19:36641254chr3:153842199ENST00000465093115106_173361872.0Compositional biasNote=Pro-rich
TgeneARHGEF26chr19:36641254chr3:153842199ENST0000046581715106_173361447.0Compositional biasNote=Pro-rich


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Fusion Gene Sequence for CAPNS1-ARHGEF26


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12904_12904_1_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000356448_length(transcript)=5805nt_BP=1918nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGCAGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGGCGG
CGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCGA
GGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAGTT
CCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACA
CCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGCTT
TGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTGCAG
TAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGAAAG
TGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGGCAC
TGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCTTGC
TATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTTTTG
TTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAACAA
GCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCACTT
GTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTGCTA
CCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGAGGA
AATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCAAAA
CTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCATAA
GCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAAAGAAAGGGATTATCTCAGACAGTAAGCCAGGAGGAAAGAAAGAGACAAGA
GGCTATCTTTGAAGTCATATCCTCTGAACATTCATATTTACTCAGCTTGGAGATCTTGATACGAATGTTTAAAAATTCTAAAGAACTGAG
TGATACAATGACTAAAACCGAGAGGCACCATCTTTTCTCCAATATTACAGATGTCTGTGAGGCAAGCAAAAAGTTCTTTATAGAGTTGGA
AGCAAGACATCAGAATAATATCTTCATAGATGACATAAGTGACATTGTGGAAAAACACACAGCATCCACATTTGACCCATATGTGAAATA
CTGCACAAATGAAGTCTACCAACAACGAACACTACAAAAATTGTTAGCTACCAATCCATCCTTTAAGGAAGTATTGTCAAGGATTGAGTC
CCATGAAGACTGTAGGAACTTACCCATGATCTCTTTTCTCATTCTCCCCATGCAGAGGGTGACCCGCCTTCCCCTGCTGATGGATACTAT
CTGTCAAAAAACACCTAAGGACTCTCCGAAGTATGAAGTCTGCAAAAGAGCCTTGAAGGAAGTTAGCAAGTTGGTTCGACTATGCAATGA
GGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTCCTC
TTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGTCTA
CTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCAGCT
ATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGCCAG
TCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGCCCG
CTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTACTGC
TAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACGACT
ACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAATGGG
ACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTTGGT
TCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCT
CTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAGAAT
AGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCCTGG
TTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCTGTA
AAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAACTG
GTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCTCAT
TAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAATTAA
CCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTCCCC
ACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTCAGC
CTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCA
GGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCCACC
GTGCCCAGCCTACTTTCTAATTAATTAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTCCCAAATGAGCTGATAAAAAACTGACGTGAGGC
TGCTTTGCCTTCAATAATACCTAGTTTTCAGCTGTTCCAACTCGTTTCCAAATAGAAATTAGCTGGAACACACTACAGTAATCTCAAGGA
AGGGAAAATTAGGCCTTAAAAGATACCAAGAAGTCAGCATGGTACCCAATTGAAACCTTTTGACCTTAGTGGGAATTCATTCTATTTGCA
CTAAAAGCCTTAACTTGCTGTATTCAGAGTCCCTCTTAACTGTGAGTTTCTATAGAACTTTACTTTTTCCACTAGTGCACAGAGAGAGAA
AGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATTAAGAGGGGGGAAATGATTTTTACTGGCAGCTATATTCCCTCTCT
GTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACATTATTGGAGGACTCAAATCTGTATGTGACATGTCCCAACTACTGT
CCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGAGGGGTAAGTGTGCCTGGCTCACACAGCCTGCACCCTGTCACCTC
GGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATTGCTCTTTTTGACCTGTGCATACCTTCTAATTGTAAAATATATTT
CAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTAATAGCAATGGTCCACAGTGAAAGATGTGTTGGGGTTTGCAAAAC
AAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGAGAGGCTATCAAGTTGTAATATAATCTGTCATGTTTTATTTAGGA
AGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTTTGCTAATACCCAGTTGAAGCTAAAAAGCAACTATTTGAATCCTG
TGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCATCTTATGAATCATAGCCTTATTTAGCAAGATCAATGTTAAAGTGT
TGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTTCAACTGTGAATTGTCTTAAGTTTTTTCAAACCTAGTTGTTTCTA
TGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACAAAAATGTTCATTTTTGTCCCAGTAAATTGAGACTGCTTGTACAC

>12904_12904_1_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000356448_length(amino acids)=529AA_BP=19
MLPACQAQEEINMPQLLISKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQT
VSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHT
ASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKE
VSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYN
VNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLT

--------------------------------------------------------------
>12904_12904_2_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000465093_length(transcript)=4553nt_BP=1918nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGCAGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGGCGG
CGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCGA
GGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAGTT
CCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACA
CCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGCTT
TGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTGCAG
TAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGAAAG
TGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGGCAC
TGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCTTGC
TATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTTTTG
TTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAACAA
GCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCACTT
GTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTGCTA
CCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGAGGA
AATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCAAAA
CTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCATAA
GCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAAAGAAAGGGATTATCTCAGACAGTAAGCCAGGAGGAAAGAAAGAGACAAGA
GGCTATCTTTGAAGTCATATCCTCTGAACATTCATATTTACTCAGCTTGGAGATCTTGATACGAATGTTTAAAAATTCTAAAGAACTGAG
TGATACAATGACTAAAACCGAGAGGCACCATCTTTTCTCCAATATTACAGATGTCTGTGAGGCAAGCAAAAAGTTCTTTATAGAGTTGGA
AGCAAGACATCAGAATAATATCTTCATAGATGACATAAGTGACATTGTGGAAAAACACACAGCATCCACATTTGACCCATATGTGAAATA
CTGCACAAATGAAGTCTACCAACAACGAACACTACAAAAATTGTTAGCTACCAATCCATCCTTTAAGGAAGTATTGTCAAGGATTGAGTC
CCATGAAGACTGTAGGAACTTACCCATGATCTCTTTTCTCATTCTCCCCATGCAGAGGGTGACCCGCCTTCCCCTGCTGATGGATACTAT
CTGTCAAAAAACACCTAAGGACTCTCCGAAGTATGAAGTCTGCAAAAGAGCCTTGAAGGAAGTTAGCAAGTTGGTTCGACTATGCAATGA
GGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTCCTC
TTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGTCTA
CTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCAGCT
ATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGCCAG
TCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGCCCG
CTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTACTGC
TAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACGACT
ACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAATGGG
ACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTTGGT
TCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCTGCT
CTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAGAAT
AGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCCTGG
TTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCTGTA
AAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAACTG
GTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCTCAT
TAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAATTAA
CCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTCCCC
ACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTCAGC
CTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGGCCA
GGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCCACC

>12904_12904_2_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000465093_length(amino acids)=529AA_BP=19
MLPACQAQEEINMPQLLISKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQT
VSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHT
ASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKE
VSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYN
VNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLT

--------------------------------------------------------------
>12904_12904_3_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000465817_length(transcript)=3057nt_BP=1918nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGCAGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGGCGG
CGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCGA
GGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCAGTT
CCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACGACA
CCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGGCTT
TGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTGCAG
TAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGAAAG
TGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGGCAC
TGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCTTGC
TATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTTTTG
TTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAACAA
GCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCACTT
GTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTGCTA
CCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGAGGA
AATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCAAAA
CTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCATAA
GCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATT
AAGAGGGGGGAAATGATTTTTACTGGCAGCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACAT
TATTGGAGGACTCAAATCTGTATGTGACATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGA
GGGGTAAGTGTGCCTGGCTCACACAGCCTGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATT
GCTCTTTTTGACCTGTGCATACCTTCTAATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTA
ATAGCAATGGTCCACAGTGAAAGATGTGTTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGA
GAGGCTATCAAGTTGTAATATAATCTGTCATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTT
TGCTAATACCCAGTTGAAGCTAAAAAGCAACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCAT
CTTATGAATCATAGCCTTATTTAGCAAGATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTT
CAACTGTGAATTGTCTTAAGTTTTTTCAAACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACA

>12904_12904_3_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000246533_ARHGEF26_chr3_153842199_ENST00000465817_length(amino acids)=268AA_BP=
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNI
EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ

--------------------------------------------------------------
>12904_12904_4_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000356448_length(transcript)=5358nt_BP=1471nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGG
CGGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAG
CGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCA
GTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACG
ACACCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGG
CTTTGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTG
CAGTAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGA
AAGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGG
CACTGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCT
TGCTATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTT
TTGTTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAA
CAAGCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCA
CTTGTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTG
CTACCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGA
GGAAATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCA
AAACTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCA
TAAGCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAAAGAAAGGGATTATCTCAGACAGTAAGCCAGGAGGAAAGAAAGAGACA
AGAGGCTATCTTTGAAGTCATATCCTCTGAACATTCATATTTACTCAGCTTGGAGATCTTGATACGAATGTTTAAAAATTCTAAAGAACT
GAGTGATACAATGACTAAAACCGAGAGGCACCATCTTTTCTCCAATATTACAGATGTCTGTGAGGCAAGCAAAAAGTTCTTTATAGAGTT
GGAAGCAAGACATCAGAATAATATCTTCATAGATGACATAAGTGACATTGTGGAAAAACACACAGCATCCACATTTGACCCATATGTGAA
ATACTGCACAAATGAAGTCTACCAACAACGAACACTACAAAAATTGTTAGCTACCAATCCATCCTTTAAGGAAGTATTGTCAAGGATTGA
GTCCCATGAAGACTGTAGGAACTTACCCATGATCTCTTTTCTCATTCTCCCCATGCAGAGGGTGACCCGCCTTCCCCTGCTGATGGATAC
TATCTGTCAAAAAACACCTAAGGACTCTCCGAAGTATGAAGTCTGCAAAAGAGCCTTGAAGGAAGTTAGCAAGTTGGTTCGACTATGCAA
TGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTC
CTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGT
CTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCA
GCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGC
CAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGC
CCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTAC
TGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACG
ACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAAT
GGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTT
GGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCT
GCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAG
AATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCC
TGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCT
GTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAA
CTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCT
CATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAAT
TAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTC
CCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTC
AGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGG
CCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCC
ACCGTGCCCAGCCTACTTTCTAATTAATTAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTCCCAAATGAGCTGATAAAAAACTGACGTGA
GGCTGCTTTGCCTTCAATAATACCTAGTTTTCAGCTGTTCCAACTCGTTTCCAAATAGAAATTAGCTGGAACACACTACAGTAATCTCAA
GGAAGGGAAAATTAGGCCTTAAAAGATACCAAGAAGTCAGCATGGTACCCAATTGAAACCTTTTGACCTTAGTGGGAATTCATTCTATTT
GCACTAAAAGCCTTAACTTGCTGTATTCAGAGTCCCTCTTAACTGTGAGTTTCTATAGAACTTTACTTTTTCCACTAGTGCACAGAGAGA
GAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAGATTAAGAGGGGGGAAATGATTTTTACTGGCAGCTATATTCCCTC
TCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTACATTATTGGAGGACTCAAATCTGTATGTGACATGTCCCAACTAC
TGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGTTGAGGGGTAAGTGTGCCTGGCTCACACAGCCTGCACCCTGTCAC
CTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGGATTGCTCTTTTTGACCTGTGCATACCTTCTAATTGTAAAATATA
TTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAAGTAATAGCAATGGTCCACAGTGAAAGATGTGTTGGGGTTTGCAA
AACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAAAGAGAGGCTATCAAGTTGTAATATAATCTGTCATGTTTTATTTA
GGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTATTTTTGCTAATACCCAGTTGAAGCTAAAAAGCAACTATTTGAATC
CTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATGCATCTTATGAATCATAGCCTTATTTAGCAAGATCAATGTTAAAG
TGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGATTTCAACTGTGAATTGTCTTAAGTTTTTTCAAACCTAGTTGTTT
CTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGAACAAAAATGTTCATTTTTGTCCCAGTAAATTGAGACTGCTTGTA

>12904_12904_4_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000356448_length(amino acids)=529AA_BP=19
MLPACQAQEEINMPQLLISKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQT
VSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHT
ASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKE
VSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYN
VNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLT

--------------------------------------------------------------
>12904_12904_5_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000465093_length(transcript)=4106nt_BP=1471nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGG
CGGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAG
CGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCA
GTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACG
ACACCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGG
CTTTGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTG
CAGTAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGA
AAGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGG
CACTGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCT
TGCTATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTT
TTGTTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAA
CAAGCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCA
CTTGTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTG
CTACCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGA
GGAAATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCA
AAACTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCA
TAAGCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAAAGAAAGGGATTATCTCAGACAGTAAGCCAGGAGGAAAGAAAGAGACA
AGAGGCTATCTTTGAAGTCATATCCTCTGAACATTCATATTTACTCAGCTTGGAGATCTTGATACGAATGTTTAAAAATTCTAAAGAACT
GAGTGATACAATGACTAAAACCGAGAGGCACCATCTTTTCTCCAATATTACAGATGTCTGTGAGGCAAGCAAAAAGTTCTTTATAGAGTT
GGAAGCAAGACATCAGAATAATATCTTCATAGATGACATAAGTGACATTGTGGAAAAACACACAGCATCCACATTTGACCCATATGTGAA
ATACTGCACAAATGAAGTCTACCAACAACGAACACTACAAAAATTGTTAGCTACCAATCCATCCTTTAAGGAAGTATTGTCAAGGATTGA
GTCCCATGAAGACTGTAGGAACTTACCCATGATCTCTTTTCTCATTCTCCCCATGCAGAGGGTGACCCGCCTTCCCCTGCTGATGGATAC
TATCTGTCAAAAAACACCTAAGGACTCTCCGAAGTATGAAGTCTGCAAAAGAGCCTTGAAGGAAGTTAGCAAGTTGGTTCGACTATGCAA
TGAGGGCGCCCGGAAGATGGAAAGGACTGAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTC
CTCTTCCCGGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATCCAAACAGCAAGT
CTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGTTACAACGTCAATGATTATTCCTTAAGAGATCA
GCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATTCTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGC
CAGTCACCTCTTTACTCTGACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGAGC
CCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGGTGGAAATCGTTAGGTCATTTAC
TGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCTCATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACG
ACTACGAGATGGAGAAAGAGGCTGGTTTCCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAAT
GGGACGCTTGCTAGGACTGGAGACCAACGTGTAGTCTCTCAGATGGTCTTTTGTTACTGCAAGATTTGCACGACACTTACCGGGCTGGTT
GGTTCTGGGCTAGTTTTATTGTTAATTTTGTCACAGCCTATTTAATTAAAAGAACGAAAACACTTGCCTTTAAGCTTGCCAGGTTGTTCT
GCTCTCTCATGAGAAGAGCTTGGATACAGTGAGTTTGCACAGCTCAGTTTTTACCTAACCACACACTTGCAGACCTCCTGAGGTACACAG
AATAGCTGAGCAGTTCACTTCAGGGATCAGGTCATCTCTGCTCCTCCTAGTTTCACCATGTTCTGGCAATAAAAAACACATATTATATCC
TGGTTTTCTCTATCCTTGCATTACTAAGGTGACTGTCTCTCTTTATACATCCTTGTATGGTTCTCCCAGTATTAGCAAGATTGTATATCT
GTAAAGAATGTCCAGTTTTGTAAATATTTCCCTGCCTTTTTTTTTCTTTTTTTACATCTGATTTTAATGCTTCGTTAACTTCAAAAGGAA
CTGGTAGAGTTCAGAAGGTGAGCTGTTGTTTTTCTAAACCTCTTCCCAGGAAGGGGACATTGACACTTGAATTTTTGTCACCTTTTTCCT
CATTAGAAGGAAAGTAGAAAGCCTTACTTTAGGATTTTTAAAAAAAAATCCATCTCACCCCATATTGTTCTTAAATAAGTATAGACTAAT
TAACCTAAGCTACCTTTAACAACGTAGAATTTAGATGGGTTCATATATGTGAGAAAAACCTGAATATAGGACAGGGGTCCTACTTTTTTC
CCCACCTCTGTCGCCCAGGCTAGAGTATAGTGGTGTGATCTTGGCCCACTGCAACCTCTGCTTCCTAGGTTCAAGTGATTCTCCTGCCTC
AGCCTCCCAAGTAGCTGGGATTGTAAGAGTATGCCACCACGCCCAGCTACTTTTTGTATTTTTAGTAGAGACAGGGTTTCATCATGTTGG
CCAGGATGGTCTCTTAACTCCTGCCCTCAAGTGATCCACCAGAGAGGAGATCCTCGGCCTCCCCAAGTGCTGGGATTATAGGCATGAGCC

>12904_12904_5_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000465093_length(amino acids)=529AA_BP=19
MLPACQAQEEINMPQLLISKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQT
VSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHT
ASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKE
VSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYN
VNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLT

--------------------------------------------------------------
>12904_12904_6_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000465817_length(transcript)=2610nt_BP=1471nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGTGAGTCGCAGCCATGTTCCTGGTTAACTCGTTCTTGAAGGG
CGGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGG
CGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAG
CGAGGCGGCTGCGCAGTACAACCCGGAGCCCCCGCCCCCACGCACACATTACTCCAACATTGAGGCCAACGAGAGTGAGGAGGTCCGGCA
GTTCCGGAGACTCTTTGCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAATAAGGTTGTGACACG
ACACCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCCGTGATGGATAGCGACACCACAGGCAAGCTGGG
CTTTGAGGAATTCAAGTACTTGTGGAACAACATCAAAAGGTGGCAGGCCATATACAAACAGTTCGACACTGACCGATCAGGGACCATTTG
CAGTAGTGAACTCCCAGGTGCCTTTGAGGCAGCAGGGTTCCACCTGAATGAGCATCTCTATAACATGATCATCCGACGCTACTCAGATGA
AAGTGGGAACATGGATTTTGACAACTTCATCAGCTGCTTGGTCAGGCTGGACGCCATGTTCCGTGCCTTCAAATCTCTTGACAAAGATGG
CACTGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACTATGTATTCCTGAACTGGAGCCCCAGACCCGCCCCCTCACTGCCT
TGCTATAGGAGTCACCTGGAGCCTCGGTCTCTCCCAGGGCCGATCCTGTCTGCAGTCACATCTTTGTGGGGCCTGCTGACCCACAAGCTT
TTGTTCTCTCAGTACTTGTTACCCAGCTTCTCAACATCCAGGGCCCAATTTGCCCTGCCTGGAGTTCCCCCTGGCTCTAGGACACTCTAA
CAAGCTCTGTCCACGGGTCTCCCCATTCCCACCAGGCCCTGCACACACCCACTCCGTAACCTCTCCCCTGTACCTGTGCCAAGCCTAGCA
CTTGTGATGCCTCCATGCCCCGAGGGCCCTCTCTCAGTTCTGGGAGGATGACTCCAGTCCCTGCACGCCCTGGCACACCCTTCACGGTTG
CTACCCAGGCGGCCAAGCTCCAGACCGTGCCAGACCCAGGTGCCCCAGTGCCTTTGTCTATATTCTGCTCCCAGCCTGCCAGGCCCAGGA
GGAAATAAACATGCCCCAGTTGCTGATCTCTAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCA
AAACTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGAGCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCA
TAAGCCATTGAGATCCACATGGAGCCAACTCTCTGCGGTGAAGAGAAAGGTTATCTTAATAGTCGGTTTCATGGAGATGAAGGATGGGAG
ATTAAGAGGGGGGAAATGATTTTTACTGGCAGCTATATTCCCTCTCTGTTCTATTTGCTTTAACAAAGGGATAAAACCTGGCAAAGTGTA
CATTATTGGAGGACTCAAATCTGTATGTGACATGTCCCAACTACTGTCCGCTAACTAGTTATCCAAATTGTAAAGCTACAGAAGCCCAGT
TGAGGGGTAAGTGTGCCTGGCTCACACAGCCTGCACCCTGTCACCTCGGCAATGAGCCAGTGTGGGGCACTGGGGACTTCTAACCCTTGG
ATTGCTCTTTTTGACCTGTGCATACCTTCTAATTGTAAAATATATTTCAGACCGTGAGTACCTTGAGATCTGAGCAACTGTGTTAATGAA
GTAATAGCAATGGTCCACAGTGAAAGATGTGTTGGGGTTTGCAAAACAAGCATTCCGTCACCTCTTTAATAATGTCACAGACTTTTTAAA
AGAGAGGCTATCAAGTTGTAATATAATCTGTCATGTTTTATTTAGGAAGGAAGGTAAATTTGTGCTTGCACGGGGATCATTTTGTATTAT
TTTTGCTAATACCCAGTTGAAGCTAAAAAGCAACTATTTGAATCCTGTGAATTAATTTATAAGAATGTTAAACAGCTTTGGAAATACATG
CATCTTATGAATCATAGCCTTATTTAGCAAGATCAATGTTAAAGTGTTGTTATATGGCAAGTATTTAACACATTCACAGTGTTTGTTTGA
TTTCAACTGTGAATTGTCTTAAGTTTTTTCAAACCTAGTTGTTTCTATGGACACCTGCTCTGAATTGTACATTGACTTCATTACTAAAGA
ACAAAAATGTTCATTTTTGTCCCAGTAAATTGAGACTGCTTGTACACTTTCAGAAAAATATGTGAATTTATAAAGATTTTGTAGATACTT

>12904_12904_6_CAPNS1-ARHGEF26_CAPNS1_chr19_36641254_ENST00000588815_ARHGEF26_chr3_153842199_ENST00000465817_length(amino acids)=268AA_BP=
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNI
EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAPNS1-ARHGEF26


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAPNS1-ARHGEF26


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAPNS1-ARHGEF26


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource