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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CAPRIN1-C11orf84 (FusionGDB2 ID:12935) |
Fusion Gene Summary for CAPRIN1-C11orf84 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CAPRIN1-C11orf84 | Fusion gene ID: 12935 | Hgene | Tgene | Gene symbol | CAPRIN1 | C11orf84 | Gene ID | 4076 | 144097 |
| Gene name | cell cycle associated protein 1 | spindlin interactor and repressor of chromatin binding | |
| Synonyms | GPIAP1|GPIP137|GRIP137|M11S1|RNG105|p137GPI | C11orf84|SPIN-DOC | |
| Cytomap | 11p13 | 11q13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | caprin-1GPI-anchored membrane protein 1GPI-anchored protein p137GPI-p137RNA granule protein 105activation/proliferation-associated protein 1caprin 1cytoplasmic activation- and proliferation-associated protein 1cytoplasmic activation/proliferation- | spindlin interactor and repressor of chromatin-binding proteinSPIN1 docking proteinhypothetical protein BC007540uncharacterized protein C11orf84 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q14444 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000533657, ENST00000341394, ENST00000389645, ENST00000529307, ENST00000530820, ENST00000532820, | ENST00000294244, | |
| Fusion gene scores | * DoF score | 11 X 11 X 7=847 | 6 X 3 X 8=144 |
| # samples | 13 | 9 | |
| ** MAII score | log2(13/847*10)=-2.70385034630374 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/144*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CAPRIN1 [Title/Abstract] AND C11orf84 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CAPRIN1(34113603)-C11orf84(63585277), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | C11orf84 | GO:0045892 | negative regulation of transcription, DNA-templated | 29061846 |
| Fusion gene breakpoints across CAPRIN1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across C11orf84 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-DU-A7T6-01A | CAPRIN1 | chr11 | 34113603 | - | C11orf84 | chr11 | 63585277 | + |
| ChimerDB4 | LGG | TCGA-DU-A7T6-01A | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| ChimerDB4 | LGG | TCGA-DU-A7T6 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
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Fusion Gene ORF analysis for CAPRIN1-C11orf84 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000533657 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| In-frame | ENST00000341394 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| In-frame | ENST00000389645 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| In-frame | ENST00000529307 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| In-frame | ENST00000530820 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| In-frame | ENST00000532820 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000341394 | CAPRIN1 | chr11 | 34113603 | + | ENST00000294244 | C11orf84 | chr11 | 63585277 | + | 3492 | 1894 | 114 | 2912 | 932 |
| ENST00000389645 | CAPRIN1 | chr11 | 34113603 | + | ENST00000294244 | C11orf84 | chr11 | 63585277 | + | 3443 | 1845 | 65 | 2863 | 932 |
| ENST00000532820 | CAPRIN1 | chr11 | 34113603 | + | ENST00000294244 | C11orf84 | chr11 | 63585277 | + | 3514 | 1916 | 25 | 2934 | 969 |
| ENST00000530820 | CAPRIN1 | chr11 | 34113603 | + | ENST00000294244 | C11orf84 | chr11 | 63585277 | + | 3395 | 1797 | 5 | 2815 | 936 |
| ENST00000529307 | CAPRIN1 | chr11 | 34113603 | + | ENST00000294244 | C11orf84 | chr11 | 63585277 | + | 3292 | 1694 | 232 | 2712 | 826 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000341394 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + | 0.003624831 | 0.99637514 |
| ENST00000389645 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + | 0.003659431 | 0.9963406 |
| ENST00000532820 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + | 0.002985869 | 0.99701416 |
| ENST00000530820 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + | 0.00322202 | 0.99677795 |
| ENST00000529307 | ENST00000294244 | CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585277 | + | 0.003435283 | 0.9965647 |
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Fusion Genomic Features for CAPRIN1-C11orf84 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585276 | + | 1.84E-08 | 1 |
| CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585276 | + | 1.84E-08 | 1 |
| CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585276 | + | 1.84E-08 | 1 |
| CAPRIN1 | chr11 | 34113603 | + | C11orf84 | chr11 | 63585276 | + | 1.84E-08 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CAPRIN1-C11orf84 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:34113603/chr11:63585277) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CAPRIN1 | . |
| FUNCTION: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs. {ECO:0000269|PubMed:17210633}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000341394 | + | 15 | 19 | 125_153 | 568 | 710.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000341394 | + | 15 | 19 | 60_94 | 568 | 710.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000389645 | + | 15 | 18 | 125_153 | 568 | 695.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000389645 | + | 15 | 18 | 60_94 | 568 | 695.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000530820 | + | 14 | 17 | 125_153 | 568 | 695.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000530820 | + | 14 | 17 | 60_94 | 568 | 695.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000532820 | + | 14 | 18 | 125_153 | 568 | 710.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000532820 | + | 14 | 18 | 60_94 | 568 | 710.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000341394 | + | 15 | 19 | 360_381 | 568 | 710.0 | Region | Note=G3BP1-binding |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000389645 | + | 15 | 18 | 360_381 | 568 | 695.0 | Region | Note=G3BP1-binding |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000530820 | + | 14 | 17 | 360_381 | 568 | 695.0 | Region | Note=G3BP1-binding |
| Hgene | CAPRIN1 | chr11:34113603 | chr11:63585277 | ENST00000532820 | + | 14 | 18 | 360_381 | 568 | 710.0 | Region | Note=G3BP1-binding |
| Tgene | C11orf84 | chr11:34113603 | chr11:63585277 | ENST00000294244 | 0 | 6 | 147_252 | 42 | 382.0 | Compositional bias | Note=Pro-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for CAPRIN1-C11orf84 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >12935_12935_1_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000341394_C11orf84_chr11_63585277_ENST00000294244_length(transcript)=3492nt_BP=1894nt CAGAGGGCTGCTGGCTGGCTAAGTCCCTCCCGCTCCCGGCTCTCGCCTCACTAGGAGCGGCTCTCGGTGCAGCGGGACAGGGCGAAGCGG CCTGCGCCCACGGAGCGCGCGACACTGCCCGGAAGGGACCACCACCCTTGCCCCCTCAGCTGCCCACTCGTGATTTCCAGCGGCCTCCGC GCGCGCACGATGCCCTCGGCCACCAGCCACAGCGGGAGCGGCAGCAAGTCGTCCGGACCGCCACCGCCGTCGGGTTCCTCCGGGAGTGAG GCGGCCGCGGGAGCCGGGGCCGCCGCGCCGGCTTCTCAGCACCCCGCAACCGGCACCGGCGCTGTCCAGACCGAGGCCATGAAGCAGATT CTCGGGGTGATCGACAAGAAACTTCGGAACCTGGAGAAGAAAAAGGGTAAGCTTGATGATTACCAGGAACGAATGAACAAAGGGGAAAGG CTTAATCAAGATCAGCTGGATGCCGTTTCTAAGTACCAGGAAGTCACAAATAATTTGGAGTTTGCAAAAGAATTACAGAGGAGTTTCATG GCACTAAGTCAAGATATTCAGAAAACAATAAAGAAGACAGCACGTCGGGAGCAGCTTATGAGAGAAGAAGCTGAACAGAAACGTTTAAAA ACTGTACTTGAGCTACAGTATGTTTTGGACAAATTGGGAGATGATGAAGTGCGGACTGACCTGAAACAAGGTTTGAATGGAGTGCCAATA TTGTCCGAAGAGGAGTTGTCATTGTTGGATGAATTCTATAAGCTAGTAGACCCTGAACGGGACATGAGCTTGAGGTTGAATGAACAGTAT GAACATGCCTCCATTCACCTGTGGGACCTGCTGGAAGGGAAGGAAAAACCTGTATGTGGAACCACCTATAAAGTTCTAAAGGAAATTGTT GAGCGTGTTTTTCAGTCAAACTACTTTGACAGCACCCACAACCACCAGAATGGGCTGTGTGAGGAAGAAGAGGCAGCCTCAGCACCTGCA GTTGAAGACCAGGTACCTGAAGCTGAACCTGAGCCAGCAGAAGAGTACACTGAGCAAAGTGAAGTTGAATCAACAGAGTATGTAAATAGA CAGTTCATGGCAGAAACACAGTTCACCAGTGGTGAAAAGGAGCAGGTAGATGAGTGGACAGTTGAAACGGTTGAGGTGGTAAATTCACTC CAGCAGCAACCTCAGGCTGCATCCCCTTCAGTACCAGAGCCCCACTCTTTGACTCCAGTGGCTCAGGCAGATCCCCTTGTGAGAAGACAG CGAGTACAAGACCTTATGGCACAAATGCAGGGTCCCTATAATTTCATACAGGATTCAATGCTGGATTTTGAAAATCAGACACTTGATCCT GCCATTGTATCTGCACAGCCTATGAATCCAACACAAAACATGGACATGCCCCAGCTGGTTTGCCCTCCAGTTCATTCTGAATCTAGACTT GCTCAGCCTAATCAAGTTCCTGTACAACCAGAAGCGACACAGGTTCCTTTGGTATCATCCACAAGTGAGGGGTACACAGCATCTCAACCC TTGTACCAGCCTTCTCATGCTACAGAGCAACGACCACAGAAGGAACCAATTGATCAGATTCAGGCAACAATCTCTTTAAATACAGACCAG ACTACAGCATCATCATCCCTTCCTGCTGCGTCTCAGCCTCAAGTATTTCAGGCTGGGACAAGCAAACCTTTACATAGCAGTGGAATCAAT GTAAATGCAGCTCCATTCCAATCCATGCAAACGGTGTTCAATATGAATGCCCCAGTTCCTCCTGTTAATGAACCAGAAACTTTAAAACAG CAAAATCAGTACCAGGCCAGTTATAACCAGAGCTTTTCTAGTCAGCCTCACCAAGTAGAACAAACAGAGCTTCAGCAAGAACAGCTTCAA ACAGTGACCCAACAGGAGAAGACCCCACCGCCTAGACCCAGCCCGCTAGAGGCAGGCAGTGATGGCTGTGAGGAGCCGAAGCAGCAGGTG TCTTGGGAGCAGGAGTTCCTGGTGGGCAGCAGCCCAGGAGGCAGCGGGCGGGCACTGTGCATGGTGTGTGGCGCTGAGATCCGGGCACCC TCGGCCGACACAGCTCGCTCGCACATCTTGGAGCAGCACCCTCACACCTTGGACCTGAGCCCTTCTGAGAAGAGCAATATCCTGGAGGCC TGGAGTGAAGGGGTGGCCCTCTTGCAAGACGTGAGAGCTGAGCAGCCGTCCCCACCCAACTCAGACTCGGGCCAGGATGCCCACCCAGAC CCAGACGCCAACCCAGACGCTGCCAGAATGCCAGCCGAAATCGTCGTTCTCCTTGACTCTGAGGATAACCCATCCCTCCCTAAAAGGAGC CGGCCCAGGGGACTCCGCCCCCTCGAGCTTCCTGCTGTCCCTGCCACAGAGCCAGGAAATAAGAAGCCCCGTGGTCAGAGATGGAAGGAA CCCCCAGGGGAAGAGCCAGTCAGAAAGAAAAGAGGCAGACCTATGACCAAAAACCTGGACCCTGACCCAGAGCCCCCATCGCCAGACTCG CCCACGGAGACTTTCGCAGCACCAGCCGAGGTCCGACACTTCACTGACGGCAGCTTCCCCGCCGGCTTCGTCTTGCAGCTCTTCTCCCAC ACCCAGCTCAGGGGCCCAGACAGCAAGGACTCACCCAAAGACAGGGAAGTGGCAGAAGGAGGCCTTCCCCGGGCGGAGAGCCCCTCTCCA GCTCCCCCTCCGGGGCTCCGCGGGACACTGGATCTCCAGGTTATCCGCGTGCGGATGGAGGAGCCCCCAGCGGTCAGCCTCCTGCAAGAC TGGTCCAGGCACCCCCAGGGCACCAAGCGTGTGGGAGCAGGTGACACCTCAGACTGGCCCACAGTTCTGTCAGAATCCAGCACCACTGTG GCAGGGAAGCCGGAAAAAGGGAATGGAGTGTAAATTCTTGCTTTCCTGGGGAGGGAGGGAGGGATGAGGCAGCGTCCCCCAGTGGCTTAT AACTCAGAGCTGCCTGGCTCACCCACCTGGTGGAGAGAGTAGAAACAGGTGCCAGGGCAGGAGGGGGCTGGGGCAGCATCCACTGTTATT TCGGGGCACTGGAAAGTGTCTGTTCCTGGCCAGGCCTGAGGTCGGCGAGGGTGGCTGAGGCTGTTGTGCAGTAGGGCACTGGGCCTGTGG AGAACACCTACCCCAGTCCTTCGCTGACCCCCACCTCTGTTTGTCCCCCATGACCTCCTCCCACCCTCCCCCTGCTCCCCACCATTCTCC CTTGGCACAGTGCCTTACACAAGAGTGGTCATAAGGGGGTTTGAACTGAGTCCCACTACCTCGGGGGACACCTCTCCTCCCCACTTGTTC AGGCTTCTAAACCAGGAGGCCTCCATTACCTCTTCCTGTCCCACCCCTGCAGAGGCCTGAAGCTGGGCCTGGGCACCCCATTCACTCCCG >12935_12935_1_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000341394_C11orf84_chr11_63585277_ENST00000294244_length(amino acids)=932AA_BP=593 MPGRDHHPCPLSCPLVISSGLRARTMPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKL RNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYV LDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNY FDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAAS PSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPV QPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQS MQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLV GSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAA RMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAP AEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGT -------------------------------------------------------------- >12935_12935_2_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000389645_C11orf84_chr11_63585277_ENST00000294244_length(transcript)=3443nt_BP=1845nt ACTAGGAGCGGCTCTCGGTGCAGCGGGACAGGGCGAAGCGGCCTGCGCCCACGGAGCGCGCGACACTGCCCGGAAGGGACCACCACCCTT GCCCCCTCAGCTGCCCACTCGTGATTTCCAGCGGCCTCCGCGCGCGCACGATGCCCTCGGCCACCAGCCACAGCGGGAGCGGCAGCAAGT CGTCCGGACCGCCACCGCCGTCGGGTTCCTCCGGGAGTGAGGCGGCCGCGGGAGCCGGGGCCGCCGCGCCGGCTTCTCAGCACCCCGCAA CCGGCACCGGCGCTGTCCAGACCGAGGCCATGAAGCAGATTCTCGGGGTGATCGACAAGAAACTTCGGAACCTGGAGAAGAAAAAGGGTA AGCTTGATGATTACCAGGAACGAATGAACAAAGGGGAAAGGCTTAATCAAGATCAGCTGGATGCCGTTTCTAAGTACCAGGAAGTCACAA ATAATTTGGAGTTTGCAAAAGAATTACAGAGGAGTTTCATGGCACTAAGTCAAGATATTCAGAAAACAATAAAGAAGACAGCACGTCGGG AGCAGCTTATGAGAGAAGAAGCTGAACAGAAACGTTTAAAAACTGTACTTGAGCTACAGTATGTTTTGGACAAATTGGGAGATGATGAAG TGCGGACTGACCTGAAACAAGGTTTGAATGGAGTGCCAATATTGTCCGAAGAGGAGTTGTCATTGTTGGATGAATTCTATAAGCTAGTAG ACCCTGAACGGGACATGAGCTTGAGGTTGAATGAACAGTATGAACATGCCTCCATTCACCTGTGGGACCTGCTGGAAGGGAAGGAAAAAC CTGTATGTGGAACCACCTATAAAGTTCTAAAGGAAATTGTTGAGCGTGTTTTTCAGTCAAACTACTTTGACAGCACCCACAACCACCAGA ATGGGCTGTGTGAGGAAGAAGAGGCAGCCTCAGCACCTGCAGTTGAAGACCAGGTACCTGAAGCTGAACCTGAGCCAGCAGAAGAGTACA CTGAGCAAAGTGAAGTTGAATCAACAGAGTATGTAAATAGACAGTTCATGGCAGAAACACAGTTCACCAGTGGTGAAAAGGAGCAGGTAG ATGAGTGGACAGTTGAAACGGTTGAGGTGGTAAATTCACTCCAGCAGCAACCTCAGGCTGCATCCCCTTCAGTACCAGAGCCCCACTCTT TGACTCCAGTGGCTCAGGCAGATCCCCTTGTGAGAAGACAGCGAGTACAAGACCTTATGGCACAAATGCAGGGTCCCTATAATTTCATAC AGGATTCAATGCTGGATTTTGAAAATCAGACACTTGATCCTGCCATTGTATCTGCACAGCCTATGAATCCAACACAAAACATGGACATGC CCCAGCTGGTTTGCCCTCCAGTTCATTCTGAATCTAGACTTGCTCAGCCTAATCAAGTTCCTGTACAACCAGAAGCGACACAGGTTCCTT TGGTATCATCCACAAGTGAGGGGTACACAGCATCTCAACCCTTGTACCAGCCTTCTCATGCTACAGAGCAACGACCACAGAAGGAACCAA TTGATCAGATTCAGGCAACAATCTCTTTAAATACAGACCAGACTACAGCATCATCATCCCTTCCTGCTGCGTCTCAGCCTCAAGTATTTC AGGCTGGGACAAGCAAACCTTTACATAGCAGTGGAATCAATGTAAATGCAGCTCCATTCCAATCCATGCAAACGGTGTTCAATATGAATG CCCCAGTTCCTCCTGTTAATGAACCAGAAACTTTAAAACAGCAAAATCAGTACCAGGCCAGTTATAACCAGAGCTTTTCTAGTCAGCCTC ACCAAGTAGAACAAACAGAGCTTCAGCAAGAACAGCTTCAAACAGTGACCCAACAGGAGAAGACCCCACCGCCTAGACCCAGCCCGCTAG AGGCAGGCAGTGATGGCTGTGAGGAGCCGAAGCAGCAGGTGTCTTGGGAGCAGGAGTTCCTGGTGGGCAGCAGCCCAGGAGGCAGCGGGC GGGCACTGTGCATGGTGTGTGGCGCTGAGATCCGGGCACCCTCGGCCGACACAGCTCGCTCGCACATCTTGGAGCAGCACCCTCACACCT TGGACCTGAGCCCTTCTGAGAAGAGCAATATCCTGGAGGCCTGGAGTGAAGGGGTGGCCCTCTTGCAAGACGTGAGAGCTGAGCAGCCGT CCCCACCCAACTCAGACTCGGGCCAGGATGCCCACCCAGACCCAGACGCCAACCCAGACGCTGCCAGAATGCCAGCCGAAATCGTCGTTC TCCTTGACTCTGAGGATAACCCATCCCTCCCTAAAAGGAGCCGGCCCAGGGGACTCCGCCCCCTCGAGCTTCCTGCTGTCCCTGCCACAG AGCCAGGAAATAAGAAGCCCCGTGGTCAGAGATGGAAGGAACCCCCAGGGGAAGAGCCAGTCAGAAAGAAAAGAGGCAGACCTATGACCA AAAACCTGGACCCTGACCCAGAGCCCCCATCGCCAGACTCGCCCACGGAGACTTTCGCAGCACCAGCCGAGGTCCGACACTTCACTGACG GCAGCTTCCCCGCCGGCTTCGTCTTGCAGCTCTTCTCCCACACCCAGCTCAGGGGCCCAGACAGCAAGGACTCACCCAAAGACAGGGAAG TGGCAGAAGGAGGCCTTCCCCGGGCGGAGAGCCCCTCTCCAGCTCCCCCTCCGGGGCTCCGCGGGACACTGGATCTCCAGGTTATCCGCG TGCGGATGGAGGAGCCCCCAGCGGTCAGCCTCCTGCAAGACTGGTCCAGGCACCCCCAGGGCACCAAGCGTGTGGGAGCAGGTGACACCT CAGACTGGCCCACAGTTCTGTCAGAATCCAGCACCACTGTGGCAGGGAAGCCGGAAAAAGGGAATGGAGTGTAAATTCTTGCTTTCCTGG GGAGGGAGGGAGGGATGAGGCAGCGTCCCCCAGTGGCTTATAACTCAGAGCTGCCTGGCTCACCCACCTGGTGGAGAGAGTAGAAACAGG TGCCAGGGCAGGAGGGGGCTGGGGCAGCATCCACTGTTATTTCGGGGCACTGGAAAGTGTCTGTTCCTGGCCAGGCCTGAGGTCGGCGAG GGTGGCTGAGGCTGTTGTGCAGTAGGGCACTGGGCCTGTGGAGAACACCTACCCCAGTCCTTCGCTGACCCCCACCTCTGTTTGTCCCCC ATGACCTCCTCCCACCCTCCCCCTGCTCCCCACCATTCTCCCTTGGCACAGTGCCTTACACAAGAGTGGTCATAAGGGGGTTTGAACTGA GTCCCACTACCTCGGGGGACACCTCTCCTCCCCACTTGTTCAGGCTTCTAAACCAGGAGGCCTCCATTACCTCTTCCTGTCCCACCCCTG CAGAGGCCTGAAGCTGGGCCTGGGCACCCCATTCACTCCCGTTCTCATTTACATCTGTTTTCCTGTTGTATATATCACCTTTGTTGACAA >12935_12935_2_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000389645_C11orf84_chr11_63585277_ENST00000294244_length(amino acids)=932AA_BP=593 MPGRDHHPCPLSCPLVISSGLRARTMPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKL RNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYV LDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNY FDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAAS PSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPV QPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQS MQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLV GSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAA RMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAP AEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGT -------------------------------------------------------------- >12935_12935_3_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000529307_C11orf84_chr11_63585277_ENST00000294244_length(transcript)=3292nt_BP=1694nt GTCTCTGAGGCCCGATTTCTCTGACGAGGGCCCAAAATGAAGAGGTCCCTGCGCGGGGGGCTCCGGGTTCAACCGACCGCCTCGTGGAGT TGGGGCGGCCTGCGTCCTGCAGCCTTGGGGTCTGTCCGCTCGGTTACCATGCACTCGAGACCTGTCGAGCGTCCCCTCTTCTTCCGTAGG AGAGAAGTGTGTTTAGAATCTTAAGGGTAAGCTTGATGATTACCAGGAACGAATGAACAAAGGGGAAAGGCTTAATCAAGATCAGCTGGA TGCCGTTTCTAAGTACCAGGAAGTCACAAATAATTTGGAGTTTGCAAAAGAATTACAGAGGAGTTTCATGGCACTAAGTCAAGATATTCA GAAAACAATAAAGAAGACAGCACGTCGGGAGCAGCTTATGAGAGAAGAAGCTGAACAGAAACGTTTAAAAACTGTACTTGAGCTACAGTA TGTTTTGGACAAATTGGGAGATGATGAAGTGCGGACTGACCTGAAACAAGGTTTGAATGGAGTGCCAATATTGTCCGAAGAGGAGTTGTC ATTGTTGGATGAATTCTATAAGCTAGTAGACCCTGAACGGGACATGAGCTTGAGGTTGAATGAACAGTATGAACATGCCTCCATTCACCT GTGGGACCTGCTGGAAGGGAAGGAAAAACCTGTATGTGGAACCACCTATAAAGTTCTAAAGGAAATTGTTGAGCGTGTTTTTCAGTCAAA CTACTTTGACAGCACCCACAACCACCAGAATGGGCTGTGTGAGGAAGAAGAGGCAGCCTCAGCACCTGCAGTTGAAGACCAGGTACCTGA AGCTGAACCTGAGCCAGCAGAAGAGTACACTGAGCAAAGTGAAGTTGAATCAACAGAGTATGTAAATAGACAGTTCATGGCAGAAACACA GTTCACCAGTGGTGAAAAGGAGCAGGTAGATGAGTGGACAGTTGAAACGGTTGAGGTGGTAAATTCACTCCAGCAGCAACCTCAGGCTGC ATCCCCTTCAGTACCAGAGCCCCACTCTTTGACTCCAGTGGCTCAGGCAGATCCCCTTGTGAGAAGACAGCGAGTACAAGACCTTATGGC ACAAATGCAGGGTCCCTATAATTTCATACAGGATTCAATGCTGGATTTTGAAAATCAGACACTTGATCCTGCCATTGTATCTGCACAGCC TATGAATCCAACACAAAACATGGACATGCCCCAGCTGGTTTGCCCTCCAGTTCATTCTGAATCTAGACTTGCTCAGCCTAATCAAGTTCC TGTACAACCAGAAGCGACACAGGTTCCTTTGGTATCATCCACAAGTGAGGGGTACACAGCATCTCAACCCTTGTACCAGCCTTCTCATGC TACAGAGCAACGACCACAGAAGGAACCAATTGATCAGATTCAGGCAACAATCTCTTTAAATACAGACCAGACTACAGCATCATCATCCCT TCCTGCTGCGTCTCAGCCTCAAGTATTTCAGGCTGGGACAAGCAAACCTTTACATAGCAGTGGAATCAATGTAAATGCAGCTCCATTCCA ATCCATGCAAACGGTGTTCAATATGAATGCCCCAGTTCCTCCTGTTAATGAACCAGAAACTTTAAAACAGCAAAATCAGTACCAGGCCAG TTATAACCAGAGCTTTTCTAGTCAGCCTCACCAAGTAGAACAAACAGAGCTTCAGCAAGAACAGCTTCAAACAGTGACCCAACAGGAGAA GACCCCACCGCCTAGACCCAGCCCGCTAGAGGCAGGCAGTGATGGCTGTGAGGAGCCGAAGCAGCAGGTGTCTTGGGAGCAGGAGTTCCT GGTGGGCAGCAGCCCAGGAGGCAGCGGGCGGGCACTGTGCATGGTGTGTGGCGCTGAGATCCGGGCACCCTCGGCCGACACAGCTCGCTC GCACATCTTGGAGCAGCACCCTCACACCTTGGACCTGAGCCCTTCTGAGAAGAGCAATATCCTGGAGGCCTGGAGTGAAGGGGTGGCCCT CTTGCAAGACGTGAGAGCTGAGCAGCCGTCCCCACCCAACTCAGACTCGGGCCAGGATGCCCACCCAGACCCAGACGCCAACCCAGACGC TGCCAGAATGCCAGCCGAAATCGTCGTTCTCCTTGACTCTGAGGATAACCCATCCCTCCCTAAAAGGAGCCGGCCCAGGGGACTCCGCCC CCTCGAGCTTCCTGCTGTCCCTGCCACAGAGCCAGGAAATAAGAAGCCCCGTGGTCAGAGATGGAAGGAACCCCCAGGGGAAGAGCCAGT CAGAAAGAAAAGAGGCAGACCTATGACCAAAAACCTGGACCCTGACCCAGAGCCCCCATCGCCAGACTCGCCCACGGAGACTTTCGCAGC ACCAGCCGAGGTCCGACACTTCACTGACGGCAGCTTCCCCGCCGGCTTCGTCTTGCAGCTCTTCTCCCACACCCAGCTCAGGGGCCCAGA CAGCAAGGACTCACCCAAAGACAGGGAAGTGGCAGAAGGAGGCCTTCCCCGGGCGGAGAGCCCCTCTCCAGCTCCCCCTCCGGGGCTCCG CGGGACACTGGATCTCCAGGTTATCCGCGTGCGGATGGAGGAGCCCCCAGCGGTCAGCCTCCTGCAAGACTGGTCCAGGCACCCCCAGGG CACCAAGCGTGTGGGAGCAGGTGACACCTCAGACTGGCCCACAGTTCTGTCAGAATCCAGCACCACTGTGGCAGGGAAGCCGGAAAAAGG GAATGGAGTGTAAATTCTTGCTTTCCTGGGGAGGGAGGGAGGGATGAGGCAGCGTCCCCCAGTGGCTTATAACTCAGAGCTGCCTGGCTC ACCCACCTGGTGGAGAGAGTAGAAACAGGTGCCAGGGCAGGAGGGGGCTGGGGCAGCATCCACTGTTATTTCGGGGCACTGGAAAGTGTC TGTTCCTGGCCAGGCCTGAGGTCGGCGAGGGTGGCTGAGGCTGTTGTGCAGTAGGGCACTGGGCCTGTGGAGAACACCTACCCCAGTCCT TCGCTGACCCCCACCTCTGTTTGTCCCCCATGACCTCCTCCCACCCTCCCCCTGCTCCCCACCATTCTCCCTTGGCACAGTGCCTTACAC AAGAGTGGTCATAAGGGGGTTTGAACTGAGTCCCACTACCTCGGGGGACACCTCTCCTCCCCACTTGTTCAGGCTTCTAAACCAGGAGGC CTCCATTACCTCTTCCTGTCCCACCCCTGCAGAGGCCTGAAGCTGGGCCTGGGCACCCCATTCACTCCCGTTCTCATTTACATCTGTTTT >12935_12935_3_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000529307_C11orf84_chr11_63585277_ENST00000294244_length(amino acids)=826AA_BP=487 MNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQG LNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEE AASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQAD PLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEG YTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNE PETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCG AEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNP SLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFV LQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVLS -------------------------------------------------------------- >12935_12935_4_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000530820_C11orf84_chr11_63585277_ENST00000294244_length(transcript)=3395nt_BP=1797nt GCGTTTTGTCCCGCGTCTCGCCCCGTCCGTCTCCTGACTGGCCGCTCTTGTCCTTCCTCCCGCTTTTTCTTCTCTCTCCTTGCGGTCTGA AGATGCCCTCGGCCACCAGCCACAGCGGGAGCGGCAGCAAGTCGTCCGGACCGCCACCGCCGTCGGGTTCCTCCGGGAGTGAGGCGGCCG CGGGAGCCGGGGCCGCCGCGCCGGCTTCTCAGCACCCCGCAACCGGCACCGGCGCTGTCCAGACCGAGGCCATGAAGCAGATTCTCGGGG TGATCGACAAGAAACTTCGGAACCTGGAGAAGAAAAAGGGTAAGCTTGATGATTACCAGGAACGAATGAACAAAGGGGAAAGGCTTAATC AAGATCAGCTGGATGCCGTTTCTAAGTACCAGGAAGTCACAAATAATTTGGAGTTTGCAAAAGAATTACAGAGGAGTTTCATGGCACTAA GTCAAGATATTCAGAAAACAATAAAGAAGACAGCACGTCGGGAGCAGCTTATGAGAGAAGAAGCTGAACAGAAACGTTTAAAAACTGTAC TTGAGCTACAGTATGTTTTGGACAAATTGGGAGATGATGAAGTGCGGACTGACCTGAAACAAGGTTTGAATGGAGTGCCAATATTGTCCG AAGAGGAGTTGTCATTGTTGGATGAATTCTATAAGCTAGTAGACCCTGAACGGGACATGAGCTTGAGGTTGAATGAACAGTATGAACATG CCTCCATTCACCTGTGGGACCTGCTGGAAGGGAAGGAAAAACCTGTATGTGGAACCACCTATAAAGTTCTAAAGGAAATTGTTGAGCGTG TTTTTCAGTCAAACTACTTTGACAGCACCCACAACCACCAGAATGGGCTGTGTGAGGAAGAAGAGGCAGCCTCAGCACCTGCAGTTGAAG ACCAGGTACCTGAAGCTGAACCTGAGCCAGCAGAAGAGTACACTGAGCAAAGTGAAGTTGAATCAACAGAGTATGTAAATAGACAGTTCA TGGCAGAAACACAGTTCACCAGTGGTGAAAAGGAGCAGGTAGATGAGTGGACAGTTGAAACGGTTGAGGTGGTAAATTCACTCCAGCAGC AACCTCAGGCTGCATCCCCTTCAGTACCAGAGCCCCACTCTTTGACTCCAGTGGCTCAGGCAGATCCCCTTGTGAGAAGACAGCGAGTAC AAGACCTTATGGCACAAATGCAGGGTCCCTATAATTTCATACAGGATTCAATGCTGGATTTTGAAAATCAGACACTTGATCCTGCCATTG TATCTGCACAGCCTATGAATCCAACACAAAACATGGACATGCCCCAGCTGGTTTGCCCTCCAGTTCATTCTGAATCTAGACTTGCTCAGC CTAATCAAGTTCCTGTACAACCAGAAGCGACACAGGTTCCTTTGGTATCATCCACAAGTGAGGGGTACACAGCATCTCAACCCTTGTACC AGCCTTCTCATGCTACAGAGCAACGACCACAGAAGGAACCAATTGATCAGATTCAGGCAACAATCTCTTTAAATACAGACCAGACTACAG CATCATCATCCCTTCCTGCTGCGTCTCAGCCTCAAGTATTTCAGGCTGGGACAAGCAAACCTTTACATAGCAGTGGAATCAATGTAAATG CAGCTCCATTCCAATCCATGCAAACGGTGTTCAATATGAATGCCCCAGTTCCTCCTGTTAATGAACCAGAAACTTTAAAACAGCAAAATC AGTACCAGGCCAGTTATAACCAGAGCTTTTCTAGTCAGCCTCACCAAGTAGAACAAACAGAGCTTCAGCAAGAACAGCTTCAAACAGTGA CCCAACAGGAGAAGACCCCACCGCCTAGACCCAGCCCGCTAGAGGCAGGCAGTGATGGCTGTGAGGAGCCGAAGCAGCAGGTGTCTTGGG AGCAGGAGTTCCTGGTGGGCAGCAGCCCAGGAGGCAGCGGGCGGGCACTGTGCATGGTGTGTGGCGCTGAGATCCGGGCACCCTCGGCCG ACACAGCTCGCTCGCACATCTTGGAGCAGCACCCTCACACCTTGGACCTGAGCCCTTCTGAGAAGAGCAATATCCTGGAGGCCTGGAGTG AAGGGGTGGCCCTCTTGCAAGACGTGAGAGCTGAGCAGCCGTCCCCACCCAACTCAGACTCGGGCCAGGATGCCCACCCAGACCCAGACG CCAACCCAGACGCTGCCAGAATGCCAGCCGAAATCGTCGTTCTCCTTGACTCTGAGGATAACCCATCCCTCCCTAAAAGGAGCCGGCCCA GGGGACTCCGCCCCCTCGAGCTTCCTGCTGTCCCTGCCACAGAGCCAGGAAATAAGAAGCCCCGTGGTCAGAGATGGAAGGAACCCCCAG GGGAAGAGCCAGTCAGAAAGAAAAGAGGCAGACCTATGACCAAAAACCTGGACCCTGACCCAGAGCCCCCATCGCCAGACTCGCCCACGG AGACTTTCGCAGCACCAGCCGAGGTCCGACACTTCACTGACGGCAGCTTCCCCGCCGGCTTCGTCTTGCAGCTCTTCTCCCACACCCAGC TCAGGGGCCCAGACAGCAAGGACTCACCCAAAGACAGGGAAGTGGCAGAAGGAGGCCTTCCCCGGGCGGAGAGCCCCTCTCCAGCTCCCC CTCCGGGGCTCCGCGGGACACTGGATCTCCAGGTTATCCGCGTGCGGATGGAGGAGCCCCCAGCGGTCAGCCTCCTGCAAGACTGGTCCA GGCACCCCCAGGGCACCAAGCGTGTGGGAGCAGGTGACACCTCAGACTGGCCCACAGTTCTGTCAGAATCCAGCACCACTGTGGCAGGGA AGCCGGAAAAAGGGAATGGAGTGTAAATTCTTGCTTTCCTGGGGAGGGAGGGAGGGATGAGGCAGCGTCCCCCAGTGGCTTATAACTCAG AGCTGCCTGGCTCACCCACCTGGTGGAGAGAGTAGAAACAGGTGCCAGGGCAGGAGGGGGCTGGGGCAGCATCCACTGTTATTTCGGGGC ACTGGAAAGTGTCTGTTCCTGGCCAGGCCTGAGGTCGGCGAGGGTGGCTGAGGCTGTTGTGCAGTAGGGCACTGGGCCTGTGGAGAACAC CTACCCCAGTCCTTCGCTGACCCCCACCTCTGTTTGTCCCCCATGACCTCCTCCCACCCTCCCCCTGCTCCCCACCATTCTCCCTTGGCA CAGTGCCTTACACAAGAGTGGTCATAAGGGGGTTTGAACTGAGTCCCACTACCTCGGGGGACACCTCTCCTCCCCACTTGTTCAGGCTTC TAAACCAGGAGGCCTCCATTACCTCTTCCTGTCCCACCCCTGCAGAGGCCTGAAGCTGGGCCTGGGCACCCCATTCACTCCCGTTCTCAT >12935_12935_4_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000530820_C11orf84_chr11_63585277_ENST00000294244_length(amino acids)=936AA_BP=597 MSRVSPRPSPDWPLLSFLPLFLLSPCGLKMPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVI DKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLE LQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVF QSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQP QAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPN QVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAA PFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQ EFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDAN PDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTET FAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRH -------------------------------------------------------------- >12935_12935_5_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000532820_C11orf84_chr11_63585277_ENST00000294244_length(transcript)=3514nt_BP=1916nt GTGCGAGGCCCAGCCGGGCGCCCCGCTGGCGGGTCGCGCGCGCGCCCGCGCACTCTTCCTGCCCTCGAGGCGCGCCGCGCCCCCTCCCCC ACCCGCTCGCGTAGGCTACCGCTCGCTGCGCGTTTTGTCCCGCGTCTCGCCCCGTCCGTCTCCTGACTGGCCGCTCTTGTCCTTCCTCCC GCTTTTTCTTCTCTCTCCTTGCGGTCTGAAGATGCCCTCGGCCACCAGCCACAGCGGGAGCGGCAGCAAGTCGTCCGGACCGCCACCGCC GTCGGGTTCCTCCGGGAGTGAGGCGGCCGCGGGAGCCGGGGCCGCCGCGCCGGCTTCTCAGCACCCCGCAACCGGCACCGGCGCTGTCCA GACCGAGGCCATGAAGCAGATTCTCGGGGTGATCGACAAGAAACTTCGGAACCTGGAGAAGAAAAAGGGTAAGCTTGATGATTACCAGGA ACGAATGAACAAAGGGGAAAGGCTTAATCAAGATCAGCTGGATGCCGTTTCTAAGTACCAGGAAGTCACAAATAATTTGGAGTTTGCAAA AGAATTACAGAGGAGTTTCATGGCACTAAGTCAAGATATTCAGAAAACAATAAAGAAGACAGCACGTCGGGAGCAGCTTATGAGAGAAGA AGCTGAACAGAAACGTTTAAAAACTGTACTTGAGCTACAGTATGTTTTGGACAAATTGGGAGATGATGAAGTGCGGACTGACCTGAAACA AGGTTTGAATGGAGTGCCAATATTGTCCGAAGAGGAGTTGTCATTGTTGGATGAATTCTATAAGCTAGTAGACCCTGAACGGGACATGAG CTTGAGGTTGAATGAACAGTATGAACATGCCTCCATTCACCTGTGGGACCTGCTGGAAGGGAAGGAAAAACCTGTATGTGGAACCACCTA TAAAGTTCTAAAGGAAATTGTTGAGCGTGTTTTTCAGTCAAACTACTTTGACAGCACCCACAACCACCAGAATGGGCTGTGTGAGGAAGA AGAGGCAGCCTCAGCACCTGCAGTTGAAGACCAGGTACCTGAAGCTGAACCTGAGCCAGCAGAAGAGTACACTGAGCAAAGTGAAGTTGA ATCAACAGAGTATGTAAATAGACAGTTCATGGCAGAAACACAGTTCACCAGTGGTGAAAAGGAGCAGGTAGATGAGTGGACAGTTGAAAC GGTTGAGGTGGTAAATTCACTCCAGCAGCAACCTCAGGCTGCATCCCCTTCAGTACCAGAGCCCCACTCTTTGACTCCAGTGGCTCAGGC AGATCCCCTTGTGAGAAGACAGCGAGTACAAGACCTTATGGCACAAATGCAGGGTCCCTATAATTTCATACAGGATTCAATGCTGGATTT TGAAAATCAGACACTTGATCCTGCCATTGTATCTGCACAGCCTATGAATCCAACACAAAACATGGACATGCCCCAGCTGGTTTGCCCTCC AGTTCATTCTGAATCTAGACTTGCTCAGCCTAATCAAGTTCCTGTACAACCAGAAGCGACACAGGTTCCTTTGGTATCATCCACAAGTGA GGGGTACACAGCATCTCAACCCTTGTACCAGCCTTCTCATGCTACAGAGCAACGACCACAGAAGGAACCAATTGATCAGATTCAGGCAAC AATCTCTTTAAATACAGACCAGACTACAGCATCATCATCCCTTCCTGCTGCGTCTCAGCCTCAAGTATTTCAGGCTGGGACAAGCAAACC TTTACATAGCAGTGGAATCAATGTAAATGCAGCTCCATTCCAATCCATGCAAACGGTGTTCAATATGAATGCCCCAGTTCCTCCTGTTAA TGAACCAGAAACTTTAAAACAGCAAAATCAGTACCAGGCCAGTTATAACCAGAGCTTTTCTAGTCAGCCTCACCAAGTAGAACAAACAGA GCTTCAGCAAGAACAGCTTCAAACAGTGACCCAACAGGAGAAGACCCCACCGCCTAGACCCAGCCCGCTAGAGGCAGGCAGTGATGGCTG TGAGGAGCCGAAGCAGCAGGTGTCTTGGGAGCAGGAGTTCCTGGTGGGCAGCAGCCCAGGAGGCAGCGGGCGGGCACTGTGCATGGTGTG TGGCGCTGAGATCCGGGCACCCTCGGCCGACACAGCTCGCTCGCACATCTTGGAGCAGCACCCTCACACCTTGGACCTGAGCCCTTCTGA GAAGAGCAATATCCTGGAGGCCTGGAGTGAAGGGGTGGCCCTCTTGCAAGACGTGAGAGCTGAGCAGCCGTCCCCACCCAACTCAGACTC GGGCCAGGATGCCCACCCAGACCCAGACGCCAACCCAGACGCTGCCAGAATGCCAGCCGAAATCGTCGTTCTCCTTGACTCTGAGGATAA CCCATCCCTCCCTAAAAGGAGCCGGCCCAGGGGACTCCGCCCCCTCGAGCTTCCTGCTGTCCCTGCCACAGAGCCAGGAAATAAGAAGCC CCGTGGTCAGAGATGGAAGGAACCCCCAGGGGAAGAGCCAGTCAGAAAGAAAAGAGGCAGACCTATGACCAAAAACCTGGACCCTGACCC AGAGCCCCCATCGCCAGACTCGCCCACGGAGACTTTCGCAGCACCAGCCGAGGTCCGACACTTCACTGACGGCAGCTTCCCCGCCGGCTT CGTCTTGCAGCTCTTCTCCCACACCCAGCTCAGGGGCCCAGACAGCAAGGACTCACCCAAAGACAGGGAAGTGGCAGAAGGAGGCCTTCC CCGGGCGGAGAGCCCCTCTCCAGCTCCCCCTCCGGGGCTCCGCGGGACACTGGATCTCCAGGTTATCCGCGTGCGGATGGAGGAGCCCCC AGCGGTCAGCCTCCTGCAAGACTGGTCCAGGCACCCCCAGGGCACCAAGCGTGTGGGAGCAGGTGACACCTCAGACTGGCCCACAGTTCT GTCAGAATCCAGCACCACTGTGGCAGGGAAGCCGGAAAAAGGGAATGGAGTGTAAATTCTTGCTTTCCTGGGGAGGGAGGGAGGGATGAG GCAGCGTCCCCCAGTGGCTTATAACTCAGAGCTGCCTGGCTCACCCACCTGGTGGAGAGAGTAGAAACAGGTGCCAGGGCAGGAGGGGGC TGGGGCAGCATCCACTGTTATTTCGGGGCACTGGAAAGTGTCTGTTCCTGGCCAGGCCTGAGGTCGGCGAGGGTGGCTGAGGCTGTTGTG CAGTAGGGCACTGGGCCTGTGGAGAACACCTACCCCAGTCCTTCGCTGACCCCCACCTCTGTTTGTCCCCCATGACCTCCTCCCACCCTC CCCCTGCTCCCCACCATTCTCCCTTGGCACAGTGCCTTACACAAGAGTGGTCATAAGGGGGTTTGAACTGAGTCCCACTACCTCGGGGGA CACCTCTCCTCCCCACTTGTTCAGGCTTCTAAACCAGGAGGCCTCCATTACCTCTTCCTGTCCCACCCCTGCAGAGGCCTGAAGCTGGGC CTGGGCACCCCATTCACTCCCGTTCTCATTTACATCTGTTTTCCTGTTGTATATATCACCTTTGTTGACAATAAATTATTTTTTTTTATT >12935_12935_5_CAPRIN1-C11orf84_CAPRIN1_chr11_34113603_ENST00000532820_C11orf84_chr11_63585277_ENST00000294244_length(amino acids)=969AA_BP=630 MAGRARARALFLPSRRAAPPPPPARVGYRSLRVLSRVSPRPSPDWPLLSFLPLFLLSPCGLKMPSATSHSGSGSKSSGPPPPSGSSGSEA AAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMA LSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYE HASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQ FMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPA IVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQT TASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQT VTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAW SEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEP PGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPA -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CAPRIN1-C11orf84 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CAPRIN1-C11orf84 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CAPRIN1-C11orf84 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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