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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAPZA2-COG5 (FusionGDB2 ID:12979)

Fusion Gene Summary for CAPZA2-COG5

check button Fusion gene summary
Fusion gene informationFusion gene name: CAPZA2-COG5
Fusion gene ID: 12979
HgeneTgene
Gene symbol

CAPZA2

COG5

Gene ID

830

10466

Gene namecapping actin protein of muscle Z-line subunit alpha 2component of oligomeric golgi complex 5
SynonymsCAPPA2|CAPZCDG2I|GOLTC1|GTC90
Cytomap

7q31.2

7q22.3

Type of geneprotein-codingprotein-coding
DescriptionF-actin-capping protein subunit alpha-2F-actin capping protein alpha-2 subunitcapZ alpha-2capping actin protein of muscle Z-line alpha subunit 2capping protein (actin filament) muscle Z-line, alpha 2epididymis secretory sperm binding proteinconserved oligomeric Golgi complex subunit 513S golgi transport complex 1 90 kDa subunitCOG complex subunit 5conserved oligomeric Golgi complex protein 5
Modification date2020031320200313
UniProtAcc.

Q9UP83

Ensembl transtripts involved in fusion geneENST00000466023, ENST00000361183, 
ENST00000458284, ENST00000490693, 
ENST00000297135, ENST00000347053, 
ENST00000393603, ENST00000475638, 
Fusion gene scores* DoF score17 X 6 X 9=91814 X 10 X 8=1120
# samples 2013
** MAII scorelog2(20/918*10)=-2.19849415363908
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/1120*10)=-3.10691520391651
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAPZA2 [Title/Abstract] AND COG5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAPZA2(116502704)-COG5(106964966), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCOG5

GO:0048219

inter-Golgi cisterna vesicle-mediated transport

9792665


check buttonFusion gene breakpoints across CAPZA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COG5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8059-01ACAPZA2chr7

116502704

+COG5chr7

106964966

-
ChimerDB4STADTCGA-BR-8059CAPZA2chr7

116502704

+COG5chr7

106964966

-


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Fusion Gene ORF analysis for CAPZA2-COG5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000466023ENST00000297135CAPZA2chr7

116502704

+COG5chr7

106964966

-
3UTR-3CDSENST00000466023ENST00000347053CAPZA2chr7

116502704

+COG5chr7

106964966

-
3UTR-3CDSENST00000466023ENST00000393603CAPZA2chr7

116502704

+COG5chr7

106964966

-
3UTR-intronENST00000466023ENST00000475638CAPZA2chr7

116502704

+COG5chr7

106964966

-
5CDS-intronENST00000361183ENST00000475638CAPZA2chr7

116502704

+COG5chr7

106964966

-
5CDS-intronENST00000458284ENST00000475638CAPZA2chr7

116502704

+COG5chr7

106964966

-
5CDS-intronENST00000490693ENST00000475638CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000361183ENST00000297135CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000361183ENST00000347053CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000361183ENST00000393603CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000458284ENST00000297135CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000458284ENST00000347053CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000458284ENST00000393603CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000490693ENST00000297135CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000490693ENST00000347053CAPZA2chr7

116502704

+COG5chr7

106964966

-
In-frameENST00000490693ENST00000393603CAPZA2chr7

116502704

+COG5chr7

106964966

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361183CAPZA2chr7116502704+ENST00000347053COG5chr7106964966-35401781001578492
ENST00000361183CAPZA2chr7116502704+ENST00000297135COG5chr7106964966-25941781001641513
ENST00000361183CAPZA2chr7116502704+ENST00000393603COG5chr7106964966-42051781001530476
ENST00000458284CAPZA2chr7116502704+ENST00000347053COG5chr7106964966-345492141492492
ENST00000458284CAPZA2chr7116502704+ENST00000297135COG5chr7106964966-250892141555513
ENST00000458284CAPZA2chr7116502704+ENST00000393603COG5chr7106964966-411992141444476
ENST00000490693CAPZA2chr7116502704+ENST00000347053COG5chr7106964966-341351121451479
ENST00000490693CAPZA2chr7116502704+ENST00000297135COG5chr7106964966-246751121514500
ENST00000490693CAPZA2chr7116502704+ENST00000393603COG5chr7106964966-407851121403463

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361183ENST00000347053CAPZA2chr7116502704+COG5chr7106964966-0.0002800340.9997199
ENST00000361183ENST00000297135CAPZA2chr7116502704+COG5chr7106964966-0.0002592640.9997408
ENST00000361183ENST00000393603CAPZA2chr7116502704+COG5chr7106964966-0.0005466650.99945337
ENST00000458284ENST00000347053CAPZA2chr7116502704+COG5chr7106964966-0.0002769560.999723
ENST00000458284ENST00000297135CAPZA2chr7116502704+COG5chr7106964966-0.0002553750.9997446
ENST00000458284ENST00000393603CAPZA2chr7116502704+COG5chr7106964966-0.0005656680.9994343
ENST00000490693ENST00000347053CAPZA2chr7116502704+COG5chr7106964966-0.0002803450.9997197
ENST00000490693ENST00000297135CAPZA2chr7116502704+COG5chr7106964966-0.0002664250.9997335
ENST00000490693ENST00000393603CAPZA2chr7116502704+COG5chr7106964966-0.0005710560.9994289

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Fusion Genomic Features for CAPZA2-COG5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CAPZA2-COG5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:116502704/chr7:106964966)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.COG5

Q9UP83

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Required for normal Golgi function. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CAPZA2-COG5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12979_12979_1_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000297135_length(transcript)=2594nt_BP=178nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGA
TGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTT
TTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATAT
CCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAA
AAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTT
CGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGA
ACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGA
GCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATT
GTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAA
GGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCA
AGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAG
AGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTT
TATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGG
TCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGT
AGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCC
TTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGGG
AGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTCAAAA
GGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACATACT
CCAAAAGACTGCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACTTATA
CTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATTTTTG
TACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATATGAT
CAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGCACAT
TCATACCAATCACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCTGACA
GACACCACTATTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAAGATA
CAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAGCAGA
CCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGATAATC
TAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCAGTGT

>12979_12979_1_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000297135_length(amino acids)=513AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIH
ALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRH
ASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQR

--------------------------------------------------------------
>12979_12979_2_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000347053_length(transcript)=3540nt_BP=178nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGA
TGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTT
TTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATAT
CCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAA
AAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTT
CGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGA
ACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGA
GCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATT
GTATAAGTTGCACCAATCAGTAACAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTAT
AGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACAT
GAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGC
TATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGA
TTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACC
TCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCAC
GAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGA
AAAGGACAGGCTCCTCCTCATCAGGGGAGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTA
TCCCATAATGGTTCAGCTGCTTCAAAAGGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCA
TTCATAGTTGGCAGTTAAACACATACTCCAAAAGACTGCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGA
CGTTTATTTACCTCTTTAGCACTTATACTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGA
AAGATGTTTTCCTCTTTCAGATTTTTGTACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAG
TCCCCACTTCTTTTAAAGGGATATGATCAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCT
CAGTGGTTTCCAAATTTGGCTGCACATTCATACCAATCACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATTAATT
AACATGTCTAGGAGTGGGAGCCTGACAGACACCACTATTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGA
ACCACTGGCACATCCCAAGCTAAGATACAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTT
ACACTTTGTCATGTTATTAAAAGCAGACCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATA
GCAATTCTCTATAAATAGTAGATAATCTAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCC
TATCAGCAGCCTCCTAATTAGCAGTGTTAGGAATTTGCCTTATGTTTTCCATCTCATCTCCTGAACCTGTTATTCTGAGAACTCATAAAT
AAAATTCAGCCAAGATTAATCAATCAATCAATCAATCAGTAGACGTCAGAGATAAGCAACTTTTTTTTCCATTTATTTGAAATAATATAC
AAGAATATAGTGTGCAAAATTTAGGGGCAACATCATGAAGAAGTGTGATGAACTGAAATCAATTTTACAGCTGTGATTCCTAACCAGAAA
CACCACTTGGTAAGTAACATGAAAAGCCATGATTGTAGCTCAGAGCAAAAGCAGCTGTATTGCCAATGTATTTGCTCTAATTTTAGACAG
TTGGAGGAAAATTAAAGTGCAAGTGTTGCACTGCAGTAAGTGCAAAGTCTGCCCCCACCATAAAGATTATGATGACAAAATATATTTAAG
ATACATGGCTGAGGAGATACAGAACACGAAGTTAAAAAATACAATGGTGTTGACTGTTTGTTAATAGCACCATTACAGTGACTATATCCC
AATGCTATTAACTAACTTTACCTTGGCCTGGGCTAGGTCTCCATTGGAAATAATAACGGATGGCTGCTGCCACCTGGTGCATCAACTCAG
CATGCCATGGTAACTGCAGCAGGTGGCTCTTAGGCTGGGACACCAACACCAGCCACCTGCCCCATGTTCTGGTAGCCTCTTGGCACTGAC
CAGACTAGGAGCGCCTATGTTTGGCACAGATGCTGAGCCATGTGGTGGTTACTAGAGGAAAGGCCGACTCCCAGCTTCTGCTTCATTTCA
TCATGTGTACAATACAGATTAATAAGCAGTAAGGAGCCAATGTATAAACAGCAGTTACATATTTTTTAAATTCCCCTTTCGTACAATTTA
AAATAAAACATGTATACACTTCTCCTCTCTTTCTACTGTACTTTAGCACCACAGGATATCAATTTTCAAGCCTATTATTACCTGATAGAC
ATATATGAAGTTTGGAAGAAAAATAAGGCAATTTGGTTTAAAATGTTGATAGTTTTAGCTTAATGCTCTAATGGAGAAAGCAAATCCTCA

>12979_12979_2_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000347053_length(amino acids)=492AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKAIHALMENAVQPLLTSVGDAIEAI
IITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQ
MELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDR

--------------------------------------------------------------
>12979_12979_3_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000393603_length(transcript)=4205nt_BP=178nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGA
TGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTT
TTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATAT
CCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAA
AAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTT
CGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGA
ACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGA
GCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATT
GTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAA
GGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCA
AGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAG
AGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTT
TATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGG
TCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGT
AGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCC
TTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGTA
AAGCCAGGTGCTCTGGGGGCACCCATCTGGTCTGGAAGCCCAAGGAGGGTGGGGATGCAAGAGAGGATGAAGGAGCAGTGCCTGGGGGCA
TGGACATGTGACTGCACCTTCCAGTGGCGGGCCACCTCACTGCCTAGGCACGGGTGCTGGAGCAACCAGCAGTTGGAAATGTTGGCCACA
ACATCTTTTGCTTTCTTTCATTCCAAACCTTCATATCCCTGATGTGCAATCCTGTGTCCCATGCAACCCTAAGGACCATGCATTTGTACC
TTTGAAAATCATCATTTGCTATGAAAAGTTTTGCCCTAGCTCCGCATCTTTTACTTCATTTTTATGTGCTGCAGTTACTGAATTGGTGGA
ACACAGATGTGAGTGAATTTTTAAAAATACCCAAGTGCGAAACAGTTCTGAGGAGGAAACAAGAACAACCCAGCAGCCACTTGGATACCA
TGGCCCTCCAGTAGTGCCCCATGAATGCATTCACATACATACGCATGTGCTCTTGCCCACACGTGCACACACCCCCATGTACCCCAACCA
TGCCCAGGGTGGGGTGCTTTAACTGTCATACATGGCTTATTAAGCAACACTCTTCCCTGCAACTGCTCTCACCATCACCAGAGACCTCTC
AGCCACCAAACATTCCCATTTTTACCTTACCACTCTGTAGCTTTAGCTACAGTTGACCGCCATTTCCTTCTGTAAACTCATAAACTGGGA
CTCAGCACATTTTTATTGATGCTGAGCTCACATTTTATCAGCATGGTAGGCCCTGGGCCAGGAACCGAGGATACGAAGTAAGCCGAGATA
TGGCCCTGTCCTCTCAGAGCTTGCATTACACCACAGCCATCTGTTTCTGTTCTAACTTCTCTGGCCATTTTTTTTTGTGTGTCATTTGCT
GAATTATCTTCTTCTAGCCATTCCTTAAATGCTATCATTTCCCATATTTTCTTCTTCTCATCCTGCCTCTGCCTTGGTTCCCAGGTGAGC
TTGTCCAGACCCATGCCTCTAGTGCCCCTTCTATACTTAAGAGCCCTCAGGTCTGTGACTGCCTCTGGATGGGGCCTTGGCCCAGTAAAC
TTGCTATCATATGTCACCACCCACAGAAATCTCAACCCCAGAATGGTCAAAATAATTCTAATCTTTTCTCTCAAACCTTCTCATTCTCTT
ATACTCCCTGTCTTGGTTGGGAGGTCACAATCACCTAACTAGCCAAGCCGGAAAACCTTTACATCATCATTCAACTCCTCTGTCATCCTT
ATTCCTCAAACCCACTCTGTTGCGTCTCTAAAATAGCTCTTGAAGTCATTCTCAACTCTCCCAGGGGATCCCAATTCTGTTGGTCTGGGC
CCACTGCACCCAGTGATCCTTTGTTAGCCTGTGTCAGGTGATGAGTTGAGTTCCCTAAAGCCAGAGTGGGGCTGACATGATGAGGTGGTT
CTAAACCACATGTGCACACAAGAATCATTTACATAGCTTGGAAAATTCCTAGTGCCCAGGTCTCTCACCCTTGCCTACCTCAGAATCTCC
AGGGTAGGCCTGCTATCAGGATTTCTCTATAGCTCCCCAAGAAGGTCCAGGGTGCAGCCAAGGGCGTGAACCCCTGCCATAGTGGGTCAT
ATTTCAGTTAGGATGAAAGACTGCTGAGGAAGCTATGACAGGTCAGTAAGAACCATCAGCCTGTCAGCTTTGTTTCCAGAAGTGACCCTG
AGCCCTCAAGCTTGGTACCCACATCCCACATGAGCCACTGGCCCTCTGGGCGTATGTGTGGATAAAGATTAGCTCGGACCCTGCTCTTTT
TCCTTGCTTATCTGTTACTCAGCTATGAACATCTGACACAGAAATGGGAGAGGTTACCAGCCCCGGTGAATGTTCCTGGTAAAATCTGCC
CTCGGGAAAGGCTTTGGATTTGGGTGAGGAGTTTGGGCCTGGGCTAACACAGGGATTTGCAATGTCTGTGTGGATTATTTTTCCCGAGTC
CCAAAGATTCACTCAGCTGCAACACACTCAGTCGTCTTAAAAAGAGGATTCAGTTAATTGAACACGTTCATTTTTCTCATCTTAACAAGT
TGGTCATTTTTGTCGTCTTAACAAGTTGGAATGAGTTCATCCAAAACAGTTGTCCTGCTGTGTGTACATCACAAATCTGTTTTCTTTTGC
TTCTCTTTAAAAATGTCTCCTGAGTGATTTCATCAGCAGTGCTGTTGCTAAGCCTATATTTAGCAACTGAAAATCATGCTCAGAAATACT
GTCATGCTTTTTTAAAAAGGCATATCCATCCCTCCACACATGGCTGATTCCAGAACCTTCATGCCCTTAGCAAAAAATTGAGCTGTCCTT
CAGGGTTTCAAAAAAAGTACTGTACTCCTGCTGCACCCCAGGCTCTTGGCAAGGAGGGGACTTTTGTCCTAGAGAATGTTCTTTCTTATG
TATTATTGCAAAACAATTTTGTTCTTGCATACTGAAGCATCACTGGATGAATTTCTTTCCCCTGTAGACAAACCGAGGGTGAGTATTGCT
CTTTAAATGTCAGTAAATTTGTTTTAGCTTCTGGGGCAAACCTTGTTGTATACTCATTCTGTTCCTCCCAGCATAATATGTTAGGTTGTC

>12979_12979_3_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000361183_COG5_chr7_106964966_ENST00000393603_length(amino acids)=476AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIH
ALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRH
ASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQR

--------------------------------------------------------------
>12979_12979_4_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000297135_length(transcript)=2508nt_BP=92nt
AAGTCAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGA
AGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGA
TGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGC
ATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATAC
CAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGAC
TCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAA
GTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAAT
CAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATT
CATTGTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTC
TAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGC
ATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTG
CCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAAC
TTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTG
TGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAAC
ATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAAT
CTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCA
GGGGAGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTC
AAAAGGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACA
TACTCCAAAAGACTGCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACT
TATACTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATT
TTTGTACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATA
TGATCAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGC
ACATTCATACCAATCACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCT
GACAGACACCACTATTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAA
GATACAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAG
CAGACCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGAT
AATCTAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCA

>12979_12979_4_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000297135_length(amino acids)=513AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIH
ALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRH
ASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQR

--------------------------------------------------------------
>12979_12979_5_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000347053_length(transcript)=3454nt_BP=92nt
AAGTCAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGA
AGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGA
TGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGC
ATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATAC
CAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGAC
TCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAA
GTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAAT
CAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATT
CATTGTATAAGTTGCACCAATCAGTAACAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATG
CTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGT
ACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTG
AGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTG
CTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCA
GACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGT
TCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCAT
CTGAAAAGGACAGGCTCCTCCTCATCAGGGGAGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAG
TTTATCCCATAATGGTTCAGCTGCTTCAAAAGGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAA
CCCATTCATAGTTGGCAGTTAAACACATACTCCAAAAGACTGCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTA
TCGACGTTTATTTACCTCTTTAGCACTTATACTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTC
CAGAAAGATGTTTTCCTCTTTCAGATTTTTGTACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCC
AAAGTCCCCACTTCTTTTAAAGGGATATGATCAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGT
AGCTCAGTGGTTTCCAAATTTGGCTGCACATTCATACCAATCACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATT
AATTAACATGTCTAGGAGTGGGAGCCTGACAGACACCACTATTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTG
AGGAACCACTGGCACATCCCAAGCTAAGATACAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTT
TGTTACACTTTGTCATGTTATTAAAAGCAGACCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTG
TATAGCAATTCTCTATAAATAGTAGATAATCTAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAA
ATCCTATCAGCAGCCTCCTAATTAGCAGTGTTAGGAATTTGCCTTATGTTTTCCATCTCATCTCCTGAACCTGTTATTCTGAGAACTCAT
AAATAAAATTCAGCCAAGATTAATCAATCAATCAATCAATCAGTAGACGTCAGAGATAAGCAACTTTTTTTTCCATTTATTTGAAATAAT
ATACAAGAATATAGTGTGCAAAATTTAGGGGCAACATCATGAAGAAGTGTGATGAACTGAAATCAATTTTACAGCTGTGATTCCTAACCA
GAAACACCACTTGGTAAGTAACATGAAAAGCCATGATTGTAGCTCAGAGCAAAAGCAGCTGTATTGCCAATGTATTTGCTCTAATTTTAG
ACAGTTGGAGGAAAATTAAAGTGCAAGTGTTGCACTGCAGTAAGTGCAAAGTCTGCCCCCACCATAAAGATTATGATGACAAAATATATT
TAAGATACATGGCTGAGGAGATACAGAACACGAAGTTAAAAAATACAATGGTGTTGACTGTTTGTTAATAGCACCATTACAGTGACTATA
TCCCAATGCTATTAACTAACTTTACCTTGGCCTGGGCTAGGTCTCCATTGGAAATAATAACGGATGGCTGCTGCCACCTGGTGCATCAAC
TCAGCATGCCATGGTAACTGCAGCAGGTGGCTCTTAGGCTGGGACACCAACACCAGCCACCTGCCCCATGTTCTGGTAGCCTCTTGGCAC
TGACCAGACTAGGAGCGCCTATGTTTGGCACAGATGCTGAGCCATGTGGTGGTTACTAGAGGAAAGGCCGACTCCCAGCTTCTGCTTCAT
TTCATCATGTGTACAATACAGATTAATAAGCAGTAAGGAGCCAATGTATAAACAGCAGTTACATATTTTTTAAATTCCCCTTTCGTACAA
TTTAAAATAAAACATGTATACACTTCTCCTCTCTTTCTACTGTACTTTAGCACCACAGGATATCAATTTTCAAGCCTATTATTACCTGAT
AGACATATATGAAGTTTGGAAGAAAAATAAGGCAATTTGGTTTAAAATGTTGATAGTTTTAGCTTAATGCTCTAATGGAGAAAGCAAATC

>12979_12979_5_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000347053_length(amino acids)=492AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKAIHALMENAVQPLLTSVGDAIEAI
IITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQ
MELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDR

--------------------------------------------------------------
>12979_12979_6_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000393603_length(transcript)=4119nt_BP=92nt
AAGTCAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGA
AGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCAGTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGA
TGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTATTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGC
ATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTCTATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATAC
CAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGACTCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGAC
TCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGTAATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAA
GTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTAGCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAAT
CAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTGATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATT
CATTGTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCCAGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTC
TAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGC
ATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTG
CCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAAC
TTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTG
TGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAAC
ATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAAT
CTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCA
GGTAAAGCCAGGTGCTCTGGGGGCACCCATCTGGTCTGGAAGCCCAAGGAGGGTGGGGATGCAAGAGAGGATGAAGGAGCAGTGCCTGGG
GGCATGGACATGTGACTGCACCTTCCAGTGGCGGGCCACCTCACTGCCTAGGCACGGGTGCTGGAGCAACCAGCAGTTGGAAATGTTGGC
CACAACATCTTTTGCTTTCTTTCATTCCAAACCTTCATATCCCTGATGTGCAATCCTGTGTCCCATGCAACCCTAAGGACCATGCATTTG
TACCTTTGAAAATCATCATTTGCTATGAAAAGTTTTGCCCTAGCTCCGCATCTTTTACTTCATTTTTATGTGCTGCAGTTACTGAATTGG
TGGAACACAGATGTGAGTGAATTTTTAAAAATACCCAAGTGCGAAACAGTTCTGAGGAGGAAACAAGAACAACCCAGCAGCCACTTGGAT
ACCATGGCCCTCCAGTAGTGCCCCATGAATGCATTCACATACATACGCATGTGCTCTTGCCCACACGTGCACACACCCCCATGTACCCCA
ACCATGCCCAGGGTGGGGTGCTTTAACTGTCATACATGGCTTATTAAGCAACACTCTTCCCTGCAACTGCTCTCACCATCACCAGAGACC
TCTCAGCCACCAAACATTCCCATTTTTACCTTACCACTCTGTAGCTTTAGCTACAGTTGACCGCCATTTCCTTCTGTAAACTCATAAACT
GGGACTCAGCACATTTTTATTGATGCTGAGCTCACATTTTATCAGCATGGTAGGCCCTGGGCCAGGAACCGAGGATACGAAGTAAGCCGA
GATATGGCCCTGTCCTCTCAGAGCTTGCATTACACCACAGCCATCTGTTTCTGTTCTAACTTCTCTGGCCATTTTTTTTTGTGTGTCATT
TGCTGAATTATCTTCTTCTAGCCATTCCTTAAATGCTATCATTTCCCATATTTTCTTCTTCTCATCCTGCCTCTGCCTTGGTTCCCAGGT
GAGCTTGTCCAGACCCATGCCTCTAGTGCCCCTTCTATACTTAAGAGCCCTCAGGTCTGTGACTGCCTCTGGATGGGGCCTTGGCCCAGT
AAACTTGCTATCATATGTCACCACCCACAGAAATCTCAACCCCAGAATGGTCAAAATAATTCTAATCTTTTCTCTCAAACCTTCTCATTC
TCTTATACTCCCTGTCTTGGTTGGGAGGTCACAATCACCTAACTAGCCAAGCCGGAAAACCTTTACATCATCATTCAACTCCTCTGTCAT
CCTTATTCCTCAAACCCACTCTGTTGCGTCTCTAAAATAGCTCTTGAAGTCATTCTCAACTCTCCCAGGGGATCCCAATTCTGTTGGTCT
GGGCCCACTGCACCCAGTGATCCTTTGTTAGCCTGTGTCAGGTGATGAGTTGAGTTCCCTAAAGCCAGAGTGGGGCTGACATGATGAGGT
GGTTCTAAACCACATGTGCACACAAGAATCATTTACATAGCTTGGAAAATTCCTAGTGCCCAGGTCTCTCACCCTTGCCTACCTCAGAAT
CTCCAGGGTAGGCCTGCTATCAGGATTTCTCTATAGCTCCCCAAGAAGGTCCAGGGTGCAGCCAAGGGCGTGAACCCCTGCCATAGTGGG
TCATATTTCAGTTAGGATGAAAGACTGCTGAGGAAGCTATGACAGGTCAGTAAGAACCATCAGCCTGTCAGCTTTGTTTCCAGAAGTGAC
CCTGAGCCCTCAAGCTTGGTACCCACATCCCACATGAGCCACTGGCCCTCTGGGCGTATGTGTGGATAAAGATTAGCTCGGACCCTGCTC
TTTTTCCTTGCTTATCTGTTACTCAGCTATGAACATCTGACACAGAAATGGGAGAGGTTACCAGCCCCGGTGAATGTTCCTGGTAAAATC
TGCCCTCGGGAAAGGCTTTGGATTTGGGTGAGGAGTTTGGGCCTGGGCTAACACAGGGATTTGCAATGTCTGTGTGGATTATTTTTCCCG
AGTCCCAAAGATTCACTCAGCTGCAACACACTCAGTCGTCTTAAAAAGAGGATTCAGTTAATTGAACACGTTCATTTTTCTCATCTTAAC
AAGTTGGTCATTTTTGTCGTCTTAACAAGTTGGAATGAGTTCATCCAAAACAGTTGTCCTGCTGTGTGTACATCACAAATCTGTTTTCTT
TTGCTTCTCTTTAAAAATGTCTCCTGAGTGATTTCATCAGCAGTGCTGTTGCTAAGCCTATATTTAGCAACTGAAAATCATGCTCAGAAA
TACTGTCATGCTTTTTTAAAAAGGCATATCCATCCCTCCACACATGGCTGATTCCAGAACCTTCATGCCCTTAGCAAAAAATTGAGCTGT
CCTTCAGGGTTTCAAAAAAAGTACTGTACTCCTGCTGCACCCCAGGCTCTTGGCAAGGAGGGGACTTTTGTCCTAGAGAATGTTCTTTCT
TATGTATTATTGCAAAACAATTTTGTTCTTGCATACTGAAGCATCACTGGATGAATTTCTTTCCCCTGTAGACAAACCGAGGGTGAGTAT
TGCTCTTTAAATGTCAGTAAATTTGTTTTAGCTTCTGGGGCAAACCTTGTTGTATACTCATTCTGTTCCTCCCAGCATAATATGTTAGGT

>12979_12979_6_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000458284_COG5_chr7_106964966_ENST00000393603_length(amino acids)=476AA_BP=26
MPPPPPRFVARRKMADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGN
FNASGTTDLYVDLQHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNV
AAVDTNLTLAVSKNVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIH
ALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRH
ASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQR

--------------------------------------------------------------
>12979_12979_7_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000297135_length(transcript)=2467nt_BP=51nt
GCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCA
GTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTA
TTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTC
TATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGAC
TCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGT
AATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTA
GCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTG
ATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCC
AGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCC
TTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAA
CCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTG
GATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAA
GGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCC
TATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTC
AGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCT
CAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGGGAGCCCTGGAAGCTTATGTTCAATCAGTGAGAAGTAGA
GAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTCAAAAGGCTATGTCTGCTCTTCAGTAATGACATGAAATCTTT
GTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACATACTCCAAAAGACTGCTACTATCTACTATTTTAAGAATGTA
ATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACTTATACTTTAGCATAAAAAATGTTGAGTTATCACCACCTTTC
AATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATTTTTGTACAAGGCTAAAATGTCTTTCCCATCCATAACCAAGT
CCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATATGATCAAGTTATAACATGTACCCTGCTTCCCCCAACCCTGC
CTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGCACATTCATACCAATCACCAGGGGATTTTTTTAAAATCCTGA
TGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCTGACAGACACCACTATTAAAAAAAAAAAAAATCCCCAAAATG
ATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAAGATACAAGGTTAAATGGCCTTTTTAAGTATGTCATACTGGA
TCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAGCAGACCTTTGGGCTGTTTAACCGTGTAACAAAAATGCCACG
TGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGATAATCTAAGTCCTTATTTTCTGATGGCTCTTGTTCCACTATT
AACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCAGTGTTAGGAATTTGCCTTATGTTTTCCATCTCATCTCCTGA

>12979_12979_7_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000297135_length(amino acids)=500AA_BP=13
MADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDL
QHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSK
NVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIHALMENAVQPLLTS
VGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKM
RLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLD

--------------------------------------------------------------
>12979_12979_8_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000347053_length(transcript)=3413nt_BP=51nt
GCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCA
GTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTA
TTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTC
TATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGAC
TCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGT
AATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTA
GCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTG
ATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACAAAGGCTATTCAT
GCTCTTATGGAAAATGCTGTGCAACCCTTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTT
TCTGGGTCATTATCCAGCTCAGGAAAACCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGT
GACTATTTTAAACACTTTGAATGCTTGGATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCAT
GCCAGTCTCATAAGACCTCTTGGTGAAGGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGT
AGACGAGTATCTGATTTAGGAAAGTCCTATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGT
CCTGCATTGGGGGATGTGATTCCGTTCAGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGG
GCAGAGTGGTCCCACACACGCTTCTCTCAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGGGAGCCCTGGAA
GCTTATGTTCAATCAGTGAGAAGTAGAGAAGGCAAAGAATTTGCACCAGTTTATCCCATAATGGTTCAGCTGCTTCAAAAGGCTATGTCT
GCTCTTCAGTAATGACATGAAATCTTTGTTCATCTCCACTTTGTGCTAACCCATTCATAGTTGGCAGTTAAACACATACTCCAAAAGACT
GCTACTATCTACTATTTTAAGAATGTAATTGATTGTTCGGTATTTCCTATCGACGTTTATTTACCTCTTTAGCACTTATACTTTAGCATA
AAAAATGTTGAGTTATCACCACCTTTCAATTCCATGGACCTGATTTTTCCAGAAAGATGTTTTCCTCTTTCAGATTTTTGTACAAGGCTA
AAATGTCTTTCCCATCCATAACCAAGTCCTCCTATGGGTACATAAACCCAAAGTCCCCACTTCTTTTAAAGGGATATGATCAAGTTATAA
CATGTACCCTGCTTCCCCCAACCCTGCCTTCTTCACTAAATAAGCATGTAGCTCAGTGGTTTCCAAATTTGGCTGCACATTCATACCAAT
CACCAGGGGATTTTTTTAAAATCCTGATGCCCAACTTGCACTCCACATTAATTAACATGTCTAGGAGTGGGAGCCTGACAGACACCACTA
TTAAAAAAAAAAAAAATCCCCAAAATGATTCCAATAGACAACAAAGTTGAGGAACCACTGGCACATCCCAAGCTAAGATACAAGGTTAAA
TGGCCTTTTTAAGTATGTCATACTGGATCTTTAAATAAAGCAAGGCTTTTGTTACACTTTGTCATGTTATTAAAAGCAGACCTTTGGGCT
GTTTAACCGTGTAACAAAAATGCCACGTGAAAAATAAAAATTTTTATTGTATAGCAATTCTCTATAAATAGTAGATAATCTAAGTCCTTA
TTTTCTGATGGCTCTTGTTCCACTATTAACATTGTTTTTAATTTTTAAAATCCTATCAGCAGCCTCCTAATTAGCAGTGTTAGGAATTTG
CCTTATGTTTTCCATCTCATCTCCTGAACCTGTTATTCTGAGAACTCATAAATAAAATTCAGCCAAGATTAATCAATCAATCAATCAATC
AGTAGACGTCAGAGATAAGCAACTTTTTTTTCCATTTATTTGAAATAATATACAAGAATATAGTGTGCAAAATTTAGGGGCAACATCATG
AAGAAGTGTGATGAACTGAAATCAATTTTACAGCTGTGATTCCTAACCAGAAACACCACTTGGTAAGTAACATGAAAAGCCATGATTGTA
GCTCAGAGCAAAAGCAGCTGTATTGCCAATGTATTTGCTCTAATTTTAGACAGTTGGAGGAAAATTAAAGTGCAAGTGTTGCACTGCAGT
AAGTGCAAAGTCTGCCCCCACCATAAAGATTATGATGACAAAATATATTTAAGATACATGGCTGAGGAGATACAGAACACGAAGTTAAAA
AATACAATGGTGTTGACTGTTTGTTAATAGCACCATTACAGTGACTATATCCCAATGCTATTAACTAACTTTACCTTGGCCTGGGCTAGG
TCTCCATTGGAAATAATAACGGATGGCTGCTGCCACCTGGTGCATCAACTCAGCATGCCATGGTAACTGCAGCAGGTGGCTCTTAGGCTG
GGACACCAACACCAGCCACCTGCCCCATGTTCTGGTAGCCTCTTGGCACTGACCAGACTAGGAGCGCCTATGTTTGGCACAGATGCTGAG
CCATGTGGTGGTTACTAGAGGAAAGGCCGACTCCCAGCTTCTGCTTCATTTCATCATGTGTACAATACAGATTAATAAGCAGTAAGGAGC
CAATGTATAAACAGCAGTTACATATTTTTTAAATTCCCCTTTCGTACAATTTAAAATAAAACATGTATACACTTCTCCTCTCTTTCTACT
GTACTTTAGCACCACAGGATATCAATTTTCAAGCCTATTATTACCTGATAGACATATATGAAGTTTGGAAGAAAAATAAGGCAATTTGGT

>12979_12979_8_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000347053_length(amino acids)=479AA_BP=13
MADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDL
QHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSK
NVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKAIHALMENAVQPLLTSVGDAIEAIIITMHQEDFSGSL
SSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKMRLAADFAQMELAVGPFCRRVS
DLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLDDHPSEKDRLLLIRGALEAYVQ

--------------------------------------------------------------
>12979_12979_9_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000393603_length(transcript)=4078nt_BP=51nt
GCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGATGGACAACCGGAAATTTTCTACACATTTTGGAATTCA
GTTACTCAGGCACTTTCTTCTCAATTTCATATGGCAACAAACTCTTCGATGTTTTTGAAGCAGGCATTTGAAGGAGAATACCCTAAATTA
TTACGTCTTTATAATGACTTATGGAAGCGTCTTCAACAATACAGTCAGCATATCCAAGGGAATTTTAATGCAAGTGGAACTACAGACCTC
TATGTTGACCTACAACACATGGAAGATGATGCACAAGATATATTCATACCAAAAAAGCCAGATTATGATCCAGAAAAGGCTTTGAAAGAC
TCACTACAACCCTATGAGGCTGCTTATCTATCAAAATCCTTATCTCGACTCTTCGATCCTATCAACTTGGTTTTTCCCCCGGGTGGTCGT
AATCCTCCTTCCTCTGATGAACTTGATGGTATTATTAAAACTATAGCAAGTGAACTAAATGTTGCTGCTGTTGATACAAACCTCACATTA
GCTGTGTCAAAAAATGTGGCAAAGACCATCCAGTTATACAGTGTAAAATCAGAGCAGCTTCTCTCCACACAAGGAGATGCAAGTCAGGTG
ATTGGGCCTCTTACTGAAGGACAGAGAAGAAATGTGGCAGTAGTGAATTCATTGTATAAGTTGCACCAATCAGTAACAAAGGTTGTTTCC
AGTCAGAGCTCATTCCCACTGGCAGCTGAGCAAACTATAATTTCAGCTCTAAAGGCTATTCATGCTCTTATGGAAAATGCTGTGCAACCC
TTACTCACTTCTGTGGGAGATGCTATAGAGGCCATAATCATCACCATGCATCAAGAAGACTTTTCTGGGTCATTATCCAGCTCAGGAAAA
CCTGATGTTCCTTGTTCTCTGTACATGAAGGAGCTACAAGGTTTCATTGCCAGAGTTATGAGTGACTATTTTAAACACTTTGAATGCTTG
GATTTTGTCTTTGACAACACTGAGGCTATTGCCCAAAGAGCTGTTGAACTTTTTATCCGCCATGCCAGTCTCATAAGACCTCTTGGTGAA
GGTGGGAAAATGCGACTTGCTGCTGATTTTGCACAGATGGAGTTGGCTGTGGGTCCATTCTGTAGACGAGTATCTGATTTAGGAAAGTCC
TATCGGATGCTGAGATCATTCAGACCTCTGCTCTTCCAGGCAAGTGAACATGTAGCCAGTAGTCCTGCATTGGGGGATGTGATTCCGTTC
AGCATCATTATTCAGTTTTTGTTCACGAGAGCACCCGCTGAACTGAAATCTCCTTTCCAGAGGGCAGAGTGGTCCCACACACGCTTCTCT
CAGTGGCTGGATGACCATCCATCTGAAAAGGACAGGCTCCTCCTCATCAGGTAAAGCCAGGTGCTCTGGGGGCACCCATCTGGTCTGGAA
GCCCAAGGAGGGTGGGGATGCAAGAGAGGATGAAGGAGCAGTGCCTGGGGGCATGGACATGTGACTGCACCTTCCAGTGGCGGGCCACCT
CACTGCCTAGGCACGGGTGCTGGAGCAACCAGCAGTTGGAAATGTTGGCCACAACATCTTTTGCTTTCTTTCATTCCAAACCTTCATATC
CCTGATGTGCAATCCTGTGTCCCATGCAACCCTAAGGACCATGCATTTGTACCTTTGAAAATCATCATTTGCTATGAAAAGTTTTGCCCT
AGCTCCGCATCTTTTACTTCATTTTTATGTGCTGCAGTTACTGAATTGGTGGAACACAGATGTGAGTGAATTTTTAAAAATACCCAAGTG
CGAAACAGTTCTGAGGAGGAAACAAGAACAACCCAGCAGCCACTTGGATACCATGGCCCTCCAGTAGTGCCCCATGAATGCATTCACATA
CATACGCATGTGCTCTTGCCCACACGTGCACACACCCCCATGTACCCCAACCATGCCCAGGGTGGGGTGCTTTAACTGTCATACATGGCT
TATTAAGCAACACTCTTCCCTGCAACTGCTCTCACCATCACCAGAGACCTCTCAGCCACCAAACATTCCCATTTTTACCTTACCACTCTG
TAGCTTTAGCTACAGTTGACCGCCATTTCCTTCTGTAAACTCATAAACTGGGACTCAGCACATTTTTATTGATGCTGAGCTCACATTTTA
TCAGCATGGTAGGCCCTGGGCCAGGAACCGAGGATACGAAGTAAGCCGAGATATGGCCCTGTCCTCTCAGAGCTTGCATTACACCACAGC
CATCTGTTTCTGTTCTAACTTCTCTGGCCATTTTTTTTTGTGTGTCATTTGCTGAATTATCTTCTTCTAGCCATTCCTTAAATGCTATCA
TTTCCCATATTTTCTTCTTCTCATCCTGCCTCTGCCTTGGTTCCCAGGTGAGCTTGTCCAGACCCATGCCTCTAGTGCCCCTTCTATACT
TAAGAGCCCTCAGGTCTGTGACTGCCTCTGGATGGGGCCTTGGCCCAGTAAACTTGCTATCATATGTCACCACCCACAGAAATCTCAACC
CCAGAATGGTCAAAATAATTCTAATCTTTTCTCTCAAACCTTCTCATTCTCTTATACTCCCTGTCTTGGTTGGGAGGTCACAATCACCTA
ACTAGCCAAGCCGGAAAACCTTTACATCATCATTCAACTCCTCTGTCATCCTTATTCCTCAAACCCACTCTGTTGCGTCTCTAAAATAGC
TCTTGAAGTCATTCTCAACTCTCCCAGGGGATCCCAATTCTGTTGGTCTGGGCCCACTGCACCCAGTGATCCTTTGTTAGCCTGTGTCAG
GTGATGAGTTGAGTTCCCTAAAGCCAGAGTGGGGCTGACATGATGAGGTGGTTCTAAACCACATGTGCACACAAGAATCATTTACATAGC
TTGGAAAATTCCTAGTGCCCAGGTCTCTCACCCTTGCCTACCTCAGAATCTCCAGGGTAGGCCTGCTATCAGGATTTCTCTATAGCTCCC
CAAGAAGGTCCAGGGTGCAGCCAAGGGCGTGAACCCCTGCCATAGTGGGTCATATTTCAGTTAGGATGAAAGACTGCTGAGGAAGCTATG
ACAGGTCAGTAAGAACCATCAGCCTGTCAGCTTTGTTTCCAGAAGTGACCCTGAGCCCTCAAGCTTGGTACCCACATCCCACATGAGCCA
CTGGCCCTCTGGGCGTATGTGTGGATAAAGATTAGCTCGGACCCTGCTCTTTTTCCTTGCTTATCTGTTACTCAGCTATGAACATCTGAC
ACAGAAATGGGAGAGGTTACCAGCCCCGGTGAATGTTCCTGGTAAAATCTGCCCTCGGGAAAGGCTTTGGATTTGGGTGAGGAGTTTGGG
CCTGGGCTAACACAGGGATTTGCAATGTCTGTGTGGATTATTTTTCCCGAGTCCCAAAGATTCACTCAGCTGCAACACACTCAGTCGTCT
TAAAAAGAGGATTCAGTTAATTGAACACGTTCATTTTTCTCATCTTAACAAGTTGGTCATTTTTGTCGTCTTAACAAGTTGGAATGAGTT
CATCCAAAACAGTTGTCCTGCTGTGTGTACATCACAAATCTGTTTTCTTTTGCTTCTCTTTAAAAATGTCTCCTGAGTGATTTCATCAGC
AGTGCTGTTGCTAAGCCTATATTTAGCAACTGAAAATCATGCTCAGAAATACTGTCATGCTTTTTTAAAAAGGCATATCCATCCCTCCAC
ACATGGCTGATTCCAGAACCTTCATGCCCTTAGCAAAAAATTGAGCTGTCCTTCAGGGTTTCAAAAAAAGTACTGTACTCCTGCTGCACC
CCAGGCTCTTGGCAAGGAGGGGACTTTTGTCCTAGAGAATGTTCTTTCTTATGTATTATTGCAAAACAATTTTGTTCTTGCATACTGAAG
CATCACTGGATGAATTTCTTTCCCCTGTAGACAAACCGAGGGTGAGTATTGCTCTTTAAATGTCAGTAAATTTGTTTTAGCTTCTGGGGC
AAACCTTGTTGTATACTCATTCTGTTCCTCCCAGCATAATATGTTAGGTTGTCATAAAATAGGGCAAATTGAGGATAGTGTAACTACTGC

>12979_12979_9_CAPZA2-COG5_CAPZA2_chr7_116502704_ENST00000490693_COG5_chr7_106964966_ENST00000393603_length(amino acids)=463AA_BP=13
MADLEEQLSDEEKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVDL
QHMEDDAQDIFIPKKPDYDPEKALKDSLQPYEAAYLSKSLSRLFDPINLVFPPGGRNPPSSDELDGIIKTIASELNVAAVDTNLTLAVSK
NVAKTIQLYSVKSEQLLSTQGDASQVIGPLTEGQRRNVAVVNSLYKLHQSVTKVVSSQSSFPLAAEQTIISALKAIHALMENAVQPLLTS
VGDAIEAIIITMHQEDFSGSLSSSGKPDVPCSLYMKELQGFIARVMSDYFKHFECLDFVFDNTEAIAQRAVELFIRHASLIRPLGEGGKM
RLAADFAQMELAVGPFCRRVSDLGKSYRMLRSFRPLLFQASEHVASSPALGDVIPFSIIIQFLFTRAPAELKSPFQRAEWSHTRFSQWLD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAPZA2-COG5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAPZA2-COG5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAPZA2-COG5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource