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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CASK-GLIPR1L1 (FusionGDB2 ID:13195)

Fusion Gene Summary for CASK-GLIPR1L1

check button Fusion gene summary
Fusion gene informationFusion gene name: CASK-GLIPR1L1
Fusion gene ID: 13195
HgeneTgene
Gene symbol

CASK

GLIPR1L1

Gene ID

8573

256710

Gene namecalcium/calmodulin dependent serine protein kinaseGLIPR1 like 1
SynonymsCAGH39|CAMGUK|CMG|FGS4|LIN2|MICPCH|MRXSNA|TNRC8|hCASKALKN2972|PRO7434
Cytomap

Xp11.4

12q21.2

Type of geneprotein-codingprotein-coding
Descriptionperipheral plasma membrane protein CASKcalcium/calmodulin-dependent serin protein kinasecalcium/calmodulin-dependent serine protein kinase (MAGUK family)calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinaseprotein linGLIPR1-like protein 1GLI pathogenesis related 1 like 1
Modification date2020032720200313
UniProtAcc

O14936

Q6UWM5

Ensembl transtripts involved in fusion geneENST00000318588, ENST00000361962, 
ENST00000378154, ENST00000378158, 
ENST00000378163, ENST00000378166, 
ENST00000421587, ENST00000442742, 
ENST00000472704, 		ENST00000548623, 
ENST00000312442, ENST00000378695, 
Fusion gene scores* DoF score13 X 12 X 5=7806 X 5 X 4=120
# samples 147
** MAII scorelog2(14/780*10)=-2.47804729680464
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CASK [Title/Abstract] AND GLIPR1L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCASK(41782183)-GLIPR1L1(75737473), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCASK

GO:0010839

negative regulation of keratinocyte proliferation

18664494


check buttonFusion gene breakpoints across CASK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GLIPR1L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A14T-01ACASKchrX

41782183

-GLIPR1L1chr12

75737473

+


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Fusion Gene ORF analysis for CASK-GLIPR1L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000318588ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000361962ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000378154ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000378158ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000378163ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000378166ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000421587ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
5CDS-intronENST00000442742ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000318588ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000318588ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000361962ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000361962ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378154ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378154ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378158ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378158ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378163ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378163ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378166ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000378166ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000421587ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000421587ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000442742ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
In-frameENST00000442742ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
intron-3CDSENST00000472704ENST00000312442CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
intron-3CDSENST00000472704ENST00000378695CASKchrX

41782183

-GLIPR1L1chr12

75737473

+
intron-intronENST00000472704ENST00000548623CASKchrX

41782183

-GLIPR1L1chr12

75737473

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000421587CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+70483107637176
ENST00000421587CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+99583107610167
ENST00000318588CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+72610521659212
ENST00000318588CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+101710521632203
ENST00000361962CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+72610521659212
ENST00000361962CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+101710521632203
ENST00000378163CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+11555342971088263
ENST00000378163CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+14465342971061254
ENST00000378158CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+1031410173964263
ENST00000378158CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+1322410173937254
ENST00000378166CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+707862640212
ENST00000378166CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+998862613203
ENST00000442742CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+69978102632176
ENST00000442742CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+99078102605167
ENST00000378154CASKchrX41782183-ENST00000378695GLIPR1L1chr1275737473+11555342971088263
ENST00000378154CASKchrX41782183-ENST00000312442GLIPR1L1chr1275737473+14465342971061254

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000421587ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.011781290.98821867
ENST00000421587ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.012170870.9878291
ENST00000318588ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0121552750.98784465
ENST00000318588ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0097485890.9902514
ENST00000361962ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0121552750.98784465
ENST00000361962ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0097485890.9902514
ENST00000378163ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0328748560.9671252
ENST00000378163ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0226110130.977389
ENST00000378158ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0322941540.9677058
ENST00000378158ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0159882770.98401165
ENST00000378166ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0127687890.9872312
ENST00000378166ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0122494070.9877506
ENST00000442742ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0119609740.98803896
ENST00000442742ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.011561560.9884384
ENST00000378154ENST00000378695CASKchrX41782183-GLIPR1L1chr1275737473+0.0328748560.9671252
ENST00000378154ENST00000312442CASKchrX41782183-GLIPR1L1chr1275737473+0.0226110130.977389

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Fusion Genomic Features for CASK-GLIPR1L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CASKchrX41782182-GLIPR1L1chr1275737472+1.10E-050.99998903
CASKchrX41782182-GLIPR1L1chr1275737472+1.10E-050.99998903

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CASK-GLIPR1L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:41782183/chr12:75737473)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CASK

O14936

GLIPR1L1

Q6UWM5

FUNCTION: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity). {ECO:0000250|UniProtKB:O70589}.FUNCTION: Plays a role in the binding between sperm and oocytes. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region. {ECO:0000250|UniProtKB:Q32LB5, ECO:0000250|UniProtKB:Q9DAG6}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-12612_27619910.0DomainProtein kinase
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126343_39819910.0DomainL27 1
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126402_45519910.0DomainL27 2
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126489_56419910.0DomainPDZ
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126612_68219910.0DomainSH3
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126739_91119910.0DomainGuanylate kinase-like
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-12712_27619927.0DomainProtein kinase
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127343_39819927.0DomainL27 1
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127402_45519927.0DomainL27 2
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127489_56419927.0DomainPDZ
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127612_68219927.0DomainSH3
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127739_91119927.0DomainGuanylate kinase-like
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-12712_27619922.0DomainProtein kinase
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127343_39819922.0DomainL27 1
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127402_45519922.0DomainL27 2
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127489_56419922.0DomainPDZ
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127612_68219922.0DomainSH3
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127739_91119922.0DomainGuanylate kinase-like
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-12512_27619898.0DomainProtein kinase
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125343_39819898.0DomainL27 1
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125402_45519898.0DomainL27 2
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125489_56419898.0DomainPDZ
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125612_68219898.0DomainSH3
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125739_91119898.0DomainGuanylate kinase-like
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-12612_27619899.0DomainProtein kinase
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126343_39819899.0DomainL27 1
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126402_45519899.0DomainL27 2
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126489_56419899.0DomainPDZ
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126612_68219899.0DomainSH3
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126739_91119899.0DomainGuanylate kinase-like
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-12618_2619910.0Nucleotide bindingATP
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-12718_2619927.0Nucleotide bindingATP
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-12718_2619922.0Nucleotide bindingATP
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-12518_2619898.0Nucleotide bindingATP
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-12618_2619899.0Nucleotide bindingATP
HgeneCASKchrX:41782183chr12:75737473ENST00000378158-126305_31519910.0RegionNote=Calmodulin-binding
HgeneCASKchrX:41782183chr12:75737473ENST00000378163-127305_31519927.0RegionNote=Calmodulin-binding
HgeneCASKchrX:41782183chr12:75737473ENST00000378166-127305_31519922.0RegionNote=Calmodulin-binding
HgeneCASKchrX:41782183chr12:75737473ENST00000421587-125305_31519898.0RegionNote=Calmodulin-binding
HgeneCASKchrX:41782183chr12:75737473ENST00000442742-126305_31519899.0RegionNote=Calmodulin-binding
TgeneGLIPR1L1chrX:41782183chr12:75737473ENST000003124420539_17158234.0DomainSCP
TgeneGLIPR1L1chrX:41782183chr12:75737473ENST000003786950639_17158243.0DomainSCP


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Fusion Gene Sequence for CASK-GLIPR1L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13195_13195_1_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000318588_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=1017nt_BP=105nt
CCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTG
CGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTG
GATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCC
ATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGG
GCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCT
GCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGC
AAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTT
TAATGTCATTTATATACAAAAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTT
TACTGAATCTTCTACACTCTTGCCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCA
GTAGAATAAAGTCTTAAGATTATTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGAT
TATCATTTTAGTTATAGTACATTTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATA

>13195_13195_1_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000318588_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=203AA_BP=28
MRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCKNPFLKP

--------------------------------------------------------------
>13195_13195_2_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000318588_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=726nt_BP=105nt
CCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTG
CGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTG
GATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCC
ATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGG
GCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCT
GCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGC
AGGACTCCACAACTTATTATACCTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGC
TTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTA

>13195_13195_2_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000318588_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=212AA_BP=28
MRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCRTPQLII

--------------------------------------------------------------
>13195_13195_3_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000361962_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=1017nt_BP=105nt
CCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTG
CGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTG
GATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCC
ATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGG
GCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCT
GCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGC
AAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTT
TAATGTCATTTATATACAAAAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTT
TACTGAATCTTCTACACTCTTGCCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCA
GTAGAATAAAGTCTTAAGATTATTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGAT
TATCATTTTAGTTATAGTACATTTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATA

>13195_13195_3_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000361962_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=203AA_BP=28
MRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCKNPFLKP

--------------------------------------------------------------
>13195_13195_4_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000361962_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=726nt_BP=105nt
CCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTG
CGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTG
GATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCC
ATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGG
GCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCT
GCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGC
AGGACTCCACAACTTATTATACCTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGC
TTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTA

>13195_13195_4_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000361962_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=212AA_BP=28
MRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCRTPQLII

--------------------------------------------------------------
>13195_13195_5_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378154_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=1446nt_BP=534nt
GCCGCCGCCACCTCCCTCCGCGGCGATCCTCGCTCCATGGTCCTGCCGCGGCCCCCTCTGTAGCCCGAGCTGCTCCGCGACGCGACGGAG
CCGGCCTCGGACAGAGGGAGCGGTCGCGGCCTCGCGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCC
GCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGAAGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGG
CCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGAGGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGA
GGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCCGGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACG
CTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGG
GATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTAT
GCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAA
ACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGT
TGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATG
CCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGCCA
ACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAA
GAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTCTT
GCCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGATT
ATTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTACA
TTTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATACCATCAACATCATTCAGAAAC

>13195_13195_5_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378154_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=254AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_6_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378154_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=1155nt_BP=534nt
GCCGCCGCCACCTCCCTCCGCGGCGATCCTCGCTCCATGGTCCTGCCGCGGCCCCCTCTGTAGCCCGAGCTGCTCCGCGACGCGACGGAG
CCGGCCTCGGACAGAGGGAGCGGTCGCGGCCTCGCGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCC
GCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGAAGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGG
CCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGAGGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGA
GGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCCGGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACG
CTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGG
GATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTAT
GCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAA
ACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGT
TGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATG
CCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTATA
CCTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGA

>13195_13195_6_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378154_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=263AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_7_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378158_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=1322nt_BP=410nt
CGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCCGCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGA
AGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGGCCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGA
GGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGAGGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCC
GGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGAC
GACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGG
CAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGT
TAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCT
CCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAG
CTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCT
GCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATC
CATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTT
ATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTCTTGCCTGATACCTAAATTTAATGTTTGTTTTTAACT
CAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGATTATTTTTTAATTACAAATCCATATGTGTATCAAAA
GTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTACATTTAGAGAACTAAAGACTTTTCACATATCAAATA

>13195_13195_7_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378158_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=254AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_8_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378158_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=1031nt_BP=410nt
CGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCCGCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGA
AGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGGCCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGA
GGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGAGGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCC
GGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGAC
GACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGG
CAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGT
TAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAACCCAATTTTATGATTTTGATAGTCTATCATGCT
CCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAG
CTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCT
GCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTATACCTAACCAAAATCCATTTCTGAAGCCAACGGGGA
GAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAGAAATTC

>13195_13195_8_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378158_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=263AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_9_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378163_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=1446nt_BP=534nt
GCCGCCGCCACCTCCCTCCGCGGCGATCCTCGCTCCATGGTCCTGCCGCGGCCCCCTCTGTAGCCCGAGCTGCTCCGCGACGCGACGGAG
CCGGCCTCGGACAGAGGGAGCGGTCGCGGCCTCGCGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCC
GCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGAAGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGG
CCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGAGGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGA
GGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCCGGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACG
CTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGG
GATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTAT
GCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAA
ACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGT
TGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATG
CCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGCCA
ACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAA
GAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTCTT
GCCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGATT
ATTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTACA
TTTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATACCATCAACATCATTCAGAAAC

>13195_13195_9_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378163_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=254AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_10_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378163_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=1155nt_BP=534nt
GCCGCCGCCACCTCCCTCCGCGGCGATCCTCGCTCCATGGTCCTGCCGCGGCCCCCTCTGTAGCCCGAGCTGCTCCGCGACGCGACGGAG
CCGGCCTCGGACAGAGGGAGCGGTCGCGGCCTCGCGGCCCGCGCGGGCTGACGAGCGGAGAGCGCGACGCCGCGCGGTCCCCGAGGATCC
GCACGCCGGGCAGCGCGGCCCGAGCAGCGCGAGAAGCAGCGGGCGGGCGGGCGGCGCCGGGCCCGGGCCGCCCTCGCTCCCGCGCCCCGG
CCCCGCCGCCCGCGCCGGGGCGGTCGCCTGCAGAGGAAGGCGCCGCAGTCTCTGGGCCTCGCGGCCCCACTCGAGCGTCCTCGGCACCGA
GGGCTCGCGGGTCCTGAGGGGAGGAGGCGATCCCGGGGCTGGGCACTGAGCTCTTGGGCGCCCCCACCCCCGTTTTCGAAGCCCTCCACG
CTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGG
GATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTAT
GCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAA
ACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGT
TGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATG
CCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTATA
CCTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGA

>13195_13195_10_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378163_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=263AA_BP=79
MQRKAPQSLGLAAPLERPRHRGLAGPEGRRRSRGWALSSWAPPPPFSKPSTLRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAK
AWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNL

--------------------------------------------------------------
>13195_13195_11_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378166_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=998nt_BP=86nt
CGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTT
GGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCT
ATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATG
AAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCG
GTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATA
TGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGC
CAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAA
AAGAAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTC
TTGCCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGA
TTATTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTA
CATTTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATACCATCAACATCATTCAGAA

>13195_13195_11_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378166_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=203AA_BP=28
LRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCKNPFLKP

--------------------------------------------------------------
>13195_13195_12_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378166_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=707nt_BP=86nt
CGCTGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTT
GGGATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCT
ATGCAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATG
AAACCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCG
GTTGTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATA
TGCCTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTA
TACCTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGA

>13195_13195_12_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000378166_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=212AA_BP=28
LRPLSPPDHGRRRRAVRGCVRAVRGDRKIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNE
TQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCRTPQLII

--------------------------------------------------------------
>13195_13195_13_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000421587_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=995nt_BP=83nt
TGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGG
ATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATG
CAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAA
CCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTT
GTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGC
CTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGCCAA
CGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAG
AAATTCTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTCTTG
CCTGATACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGATTA
TTTTTTAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTACAT
TTAGAGAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATACCATCAACATCATTCAGAAACA

>13195_13195_13_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000421587_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=167AA_BP=
MAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMC

--------------------------------------------------------------
>13195_13195_14_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000421587_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=704nt_BP=83nt
TGCGGCCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGG
ATAAAGGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATG
CAGCTTTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAA
CCCAATTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTT
GTGCAGTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGC
CTCCTTACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTATAC
CTAACCAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAA

>13195_13195_14_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000421587_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=176AA_BP=
MAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMC

--------------------------------------------------------------
>13195_13195_15_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000442742_GLIPR1L1_chr12_75737473_ENST00000312442_length(transcript)=990nt_BP=78nt
CCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGGATAAA
GGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATGCAGCT
TTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAACCCAA
TTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTTGTGCA
GTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGCCTCCT
TACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAAAAATCCATTTCTGAAGCCAACGGGG
AGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTTTAATGTCATTTATATACAAAAGAAATT
CTCAAATGTTAAAATAAAGGAATAGTTTATTGCTTAATATAACTTATCATCACTTTGCTTCTTTACTGAATCTTCTACACTCTTGCCTGA
TACCTAAATTTAATGTTTGTTTTTAACTCAAAAAATGTACTGTAGTATGGAAAATGGATAGCAGTAGAATAAAGTCTTAAGATTATTTTT
TAATTACAAATCCATATGTGTATCAAAAGTGTTCCACTCTTTAATTTTCTAATGAGAATGGATTATCATTTTAGTTATAGTACATTTAGA
GAACTAAAGACTTTTCACATATCAAATAGTTTCCTTAGATACCAATAGTTTCCTTTATGAATACCATCAACATCATTCAGAAACAAAATG

>13195_13195_15_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000442742_GLIPR1L1_chr12_75737473_ENST00000312442_length(amino acids)=167AA_BP=
MAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMC

--------------------------------------------------------------
>13195_13195_16_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000442742_GLIPR1L1_chr12_75737473_ENST00000378695_length(transcript)=699nt_BP=78nt
CCGCTATCCCCTCCGGACCATGGCCGACGACGACGTGCTGTTCGAGGATGTGTACGAGCTGTGCGAGGTGATCGGAAAATTTGGGATAAA
GGTTTAGCAAAGATGGCTAAAGCATGGGCAAACCAGTGCAAATTTGAACATAATGACTGTTTGGATAAATCATATAAATGCTATGCAGCT
TTTGAATATGTTGGAGAAAATATCTGGTTAGGTGGAATAAAGTCATTCACACCAAGACATGCCATTACGGCTTGGTATAATGAAACCCAA
TTTTATGATTTTGATAGTCTATCATGCTCCAGAGTCTGTGGCCATTATACACAGTTAGTTTGGGCCAATTCATTTTATGTCGGTTGTGCA
GTTGCAATGTGTCCTAACCTTGGGGGAGCTTCAACTGCAATATTTGTATGCAACTACGGACCTGCAGGAAATTTTGCAAATATGCCTCCT
TACGTAAGAGGAGAATCTTGCTCTCTCTGCTCAAAAGAAGAGAAATGTGTAAAGAACCTCTGCAGGACTCCACAACTTATTATACCTAAC
CAAAATCCATTTCTGAAGCCAACGGGGAGAGCACCTCAGCAGACAGCCTTTAATCCATTCAGCTTAGGTTTTCTTCTTCTGAGAATCTTT

>13195_13195_16_CASK-GLIPR1L1_CASK_chrX_41782183_ENST00000442742_GLIPR1L1_chr12_75737473_ENST00000378695_length(amino acids)=176AA_BP=
MAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CASK-GLIPR1L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CASK-GLIPR1L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CASK-GLIPR1L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource