Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CCAR1-DDX21 (FusionGDB2 ID:13517)

Fusion Gene Summary for CCAR1-DDX21

Fusion gene summary

Fusion gene information	Fusion gene name: CCAR1-DDX21
	Fusion gene ID: 13517
		Hgene	Tgene
	Gene symbol	CCAR1	DDX21
	Gene ID	55749	54606
	Gene name	cell division cycle and apoptosis regulator 1	DEAD-box helicase 56
	Synonyms	-	DDX21\|DDX26\|NOH61
	Cytomap	10q21.3	7p13
	Type of gene	protein-coding	protein-coding
	Description	cell division cycle and apoptosis regulator protein 1cell cycle and apoptosis regulatory protein 1death inducer with SAP domain	probable ATP-dependent RNA helicase DDX5661-kd nucleolar helicaseATP-dependent 61 kDa nucleolar RNA helicaseDEAD (Asp-Glu-Ala-Asp) box helicase 56DEAD (Asp-Glu-Ala-Asp) box polypeptide 56DEAD box protein 21DEAD box protein 56DEAD-box RNA helicasen
	Modification date	20200313	20200313
	UniProtAcc	Q8IX12	Q9NR30
	Ensembl transtripts involved in fusion gene	ENST00000265872, ENST00000535016, ENST00000543719, ENST00000483264,	ENST00000354185,
Fusion gene scores	* DoF score	13 X 11 X 8=1144	36 X 11 X 14=5544
	# samples	17	37
	** MAII score	log2(17/1144*10)=-2.75048040064069 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(37/5544*10)=-3.9053300816209 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CCAR1 [Title/Abstract] AND DDX21 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CCAR1(70482334)-DDX21(70723046), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CCAR1	GO:0043065	positive regulation of apoptotic process	12816952

Fusion gene breakpoints across CCAR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across DDX21 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-VQ-A8PE	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+

Top

Fusion Gene ORF analysis for CCAR1-DDX21

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000265872	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+
In-frame	ENST00000535016	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+
In-frame	ENST00000543719	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+
intron-3CDS	ENST00000483264	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000535016

CCAR1

chr10

70482334

ENST00000354185

DDX21

chr10

70723046

4198

192

119

1936

605

ENST00000265872

CCAR1

chr10

70482334

ENST00000354185

DDX21

chr10

70723046

4198

192

119

1936

605

ENST00000543719

CCAR1

chr10

70482334

ENST00000354185

DDX21

chr10

70723046

4192

186

113

1930

605

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000535016	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+	0.000734407	0.9992656
ENST00000265872	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+	0.000734407	0.9992656
ENST00000543719	ENST00000354185	CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+	0.000725499	0.99927455

Top

Fusion Genomic Features for CCAR1-DDX21

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+	0.000552974	0.99944705
CCAR1	chr10	70482334	+	DDX21	chr10	70723046	+	0.000552974	0.99944705

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CCAR1-DDX21

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:70482334/chr10:70723046)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CCAR1 Q8IX12	DDX21 Q9NR30
FUNCTION: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938). {ECO:0000250\|UniProtKB:Q8CH18, ECO:0000269\|PubMed:12816952, ECO:0000269\|PubMed:23887938, ECO:0000269\|PubMed:24245781}.	FUNCTION: RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from polymerase II (Pol II) (PubMed:25470060, PubMed:28790157). Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs (PubMed:25470060). In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification. Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes (PubMed:25470060, PubMed:25477391). In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes (PubMed:25470060). Functions as cofactor for JUN-activated transcription: required for phosphorylation of JUN at 'Ser-77' (PubMed:11823437, PubMed:25260534). Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase) (PubMed:9461305). Together with SIRT7, required to prevent R-loop-associated DNA damage and transcription-associated genomic instability: deacetylation by SIRT7 activates the helicase activity, thereby overcoming R-loop-mediated stalling of RNA polymerases (PubMed:28790157). Involved in rRNA processing (PubMed:14559904, PubMed:18180292). May bind to specific miRNA hairpins (PubMed:28431233). Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1 (By similarity). {ECO:0000250\|UniProtKB:Q9JIK5, ECO:0000269\|PubMed:11823437, ECO:0000269\|PubMed:14559904, ECO:0000269\|PubMed:18180292, ECO:0000269\|PubMed:25260534, ECO:0000269\|PubMed:25470060, ECO:0000269\|PubMed:25477391, ECO:0000269\|PubMed:28431233, ECO:0000269\|PubMed:28790157, ECO:0000269\|PubMed:9461305}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

217_396

202

784.0

Domain

Helicase ATP-binding

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

429_573

202

784.0

Domain

Helicase C-terminal

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

339_342

202

784.0

Motif

DEAD box

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

230_237

202

784.0

Nucleotide binding

ATP

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

724_748

202

784.0

Region

Note=3 X 5 AA repeats

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

724_728

202

784.0

Repeat

Note=1

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

734_738

202

784.0

Repeat

Note=2

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

744_748

202

784.0

Repeat

Note=3

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

1033_1114

1151.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

594_618

1151.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

1033_1114

1136.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

594_618

1136.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

1033_1114

1136.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

594_618

1136.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

293_361

1151.0

Compositional bias

Note=Arg-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

673_889

1151.0

Compositional bias

Note=Glu-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

73_79

1151.0

Compositional bias

Note=Poly-Ala

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

293_361

1136.0

Compositional bias

Note=Arg-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

673_889

1136.0

Compositional bias

Note=Glu-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

73_79

1136.0

Compositional bias

Note=Poly-Ala

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

293_361

1136.0

Compositional bias

Note=Arg-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

673_889

1136.0

Compositional bias

Note=Glu-rich

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

73_79

1136.0

Compositional bias

Note=Poly-Ala

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000265872

636_670

1151.0

Domain

SAP

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000535016

636_670

1136.0

Domain

SAP

Hgene

CCAR1

chr10:70482334

chr10:70723046

ENST00000543719

636_670

1136.0

Domain

SAP

Tgene

DDX21

chr10:70482334

chr10:70723046

ENST00000354185

186_214

202

784.0

Motif

Q motif

Top

Fusion Gene Sequence for CCAR1-DDX21

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>13517_13517_1_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000265872_DDX21_chr10_70723046_ENST00000354185_length(transcript)=4198nt_BP=192nt
GAAGTTGGCGCATGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGATCGATGCTATAGAAGACAAA
CAAGGGAAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAG
TATCACAGCCAGGCCGAGGAGTGACCTTCCTATTTCCTATACAAGCAAAGACATTCCATCATGTTTACAGCGGGAAGGACTTAATTGCAC
AGGCACGGACAGGAACTGGGAAGACATTCTCCTTTGCCATCCCTTTGATTGAGAAACTTCATGGGGAACTGCAAGACAGGAAGAGAGGCC
GTGCCCCTCAGGTACTGGTTCTTGCACCTACAAGAGAGTTGGCAAATCAAGTAAGCAAAGACTTCAGTGACATCACAAAAAAGCTGTCAG
TGGCTTGTTTTTATGGTGGAACTCCCTATGGAGGTCAATTTGAACGCATGAGGAATGGGATTGATATCCTGGTTGGAACACCAGGTCGTA
TCAAAGACCACATACAGAATGGCAAACTAGATCTCACCAAACTTAAGCATGTTGTCCTGGATGAAGTGGACCAGATGTTGGATATGGGAT
TTGCTGATCAAGTGGAAGAGATTTTAAGTGTGGCATACAAGAAAGATTCTGAAGACAATCCCCAAACATTGCTTTTTTCTGCAACTTGCC
CTCATTGGGTATTTAATGTTGCCAAGAAATACATGAAATCTACATATGAACAGGTGGACCTGATTGGTAAAAAGACTCAGAAAACGGCAA
TAACTGTGGAGCATCTGGCTATTAAGTGCCACTGGACTCAGAGGGCAGCAGTTATTGGGGATGTCATCCGAGTATATAGTGGTCATCAAG
GACGCACTATCATCTTTTGTGAAACCAAGAAAGAAGCCCAGGAGCTGTCCCAGAATTCAGCTATAAAGCAGGATGCTCAGTCCTTGCATG
GAGACATTCCACAGAAGCAAAGGGAAATCACCCTGAAAGGTTTTAGAAATGGTAGTTTTGGAGTTTTGGTGGCAACCAATGTTGCTGCAC
GTGGGTTAGACATCCCTGAGGTTGATTTGGTTATACAAAGCTCTCCACCAAAGGATGTAGAGTCCTACATTCATCGATCCGGGCGGACAG
GCAGAGCTGGAAGGACGGGGGTGTGCATCTGCTTTTATCAGCACAAGGAAGAATATCAGTTAGTACAAGTGGAGCAAAAAGCGGGAATTA
AGTTCAAACGAATAGGTGTTCCTTCTGCAACAGAAATAATAAAAGCTTCCAGCAAAGATGCCATCAGGCTTTTGGATTCCGTGCCTCCCA
CTGCCATTAGTCACTTCAAACAATCAGCTGAGAAGCTGATAGAGGAGAAGGGAGCTGTGGAAGCTCTGGCAGCAGCACTGGCCCATATTT
CAGGTGCCACGTCCGTAGACCAGCGCTCCTTGATCAACTCAAATGTGGGTTTTGTGACCATGATCTTGCAGTGCTCAATTGAAATGCCAA
ATATTAGTTATGCTTGGAAAGAACTTAAAGAGCAGCTGGGCGAGGAGATTGATTCCAAAGTGAAGGGAATGGTTTTTCTCAAAGGAAAGC
TGGGTGTTTGCTTTGATGTACCTACCGCATCAGTAACAGAAATACAGGAGAAATGGCATGATTCACGACGCTGGCAGCTCTCTGTGGCCA
CAGAGCAACCAGAACTGGAAGGACCACGGGAAGGATATGGAGGCTTCAGGGGACAGCGGGAAGGCAGTCGAGGCTTCAGGGGACAGCGGG
ACGGAAACAGAAGATTCAGAGGACAGCGGGAAGGCAGTAGAGGCCCGAGAGGACAGCGATCAGGAGGTGGCAACAAAAGTAACAGATCCC
AAAACAAAGGCCAGAAGCGGAGTTTCAGTAAAGCATTTGGTCAATAATTAGAAATAGAAGATTTATATAGCAAAAAGAGAATGATGTTTG
GCAATATAGAACTGAACATTATTTTTCATGCAAAGTTAAAAGCACATTGTGCCTCCTTTTGACCACTTGCCAAGTCCCTGTCTCTTTCAG
ACACAGACAAGCTTCATTTAAATTATTTCATCTGATCATTATCATTTATAACTTTATTGTTACTTCTTCATCAGTTTTTCCTTTTGAAAG
GTGTATGAATTCATTACATTTTTATTCTAATGTATTATCTGTAGATTAGAAGATAAAATCAAGCATGTATCTGCCTATACTTTGTGAGTT
CACCTGTCTTTATACTCAAAAGTGTCCCTTAATAGTGTCCTTCCCTGAAATAAATACCTAAGGGAGTGTAACAGTCTCTGGAGGACCACT
TTGAGCCTTTGGAAGTTAAGGTTTCCTCAGCCACCTGCCGAACAGTTTCTCATGTGGTCCTATTATTTGTCTACTGAGACTTAATACTGA
GCAATGTTTTGAAACAAGATTTCAAACTAATCTGGGTTGTAATACAGTTTATACCAGTGTATGCTCTAGACTTGGAAGATGTAGTATGTT
TGATGTGGATTACCTATACTTATGTTCGTTTTGATACATTTTTAGCTTCTCATTATAAGGTGATTCATGCTTTAGTGAATTCTTCATAGA
TAGTATATATAAAAGTACATTTTAATAGAAAGCCAGGGTTTTAAGGAATTTCACATGTATAAGGTGGCTCCATAGCTTTATTTGTAAGTA
GGCTGGATAAATGGTGCTTAAATGGTAATGTACTCCACTTCTTCCTATTGGAAGATTAACATTATTTACCAAGAAGGACTTAAGGGAGTA
GGGGGCGCAGATTAGCATTGCTCAAGAGTATGTAAAAAAAAAAAAAAAAAAAAAGAACCAAACCACTGGAAATAATCAAATGCAAAAAGG
TAACAAATTCATAACTGGAAAGCAAAGAGAAGAACAAGTATGATTTGGATGATAAAGCATTGTTTTAATGGTGAAAACTTCACAGATCAC
TAATGTTTCTAGAGGTTAACTTCAAGTGGGCAAGCTGGGGTTTTTAGGTAGTCAGTGGCCTAGTTCCTAAAGCCACAGTATAGGATCTGT
TAAACTGAATGTCTGTTGAAAGTTTGTTTTAGCTGCTTGGAGGCTTCCTTTTAAGACAAACTGTATGTGATTAAGTTGTTTTGAGGGAAC
TGAAGAACCTGATGTAGCCCCTGGCCAGATAACTGCCTGATTTCTCAGATATTATTTCTCTGGGAAACATTCTACATAGCACAGGAGCTT
AAGAGTGGCATTATCTTCTCGCCTTAATTTCCAGAGATTATTTCTGTACTGAGAATCCTGGAACTACTATGCTAGGAAATTTAAAGCTGC
ATGGTCTGTCTTGTTTTCATTTAATTATTGTGAATACCTAGAATCTTTCTTGGTCCTGATTTCTCTTGCTTAATCCAGTCTTTATCTCTA
ACTGCCCCTTATTTGATCACCATGTACTAGGAGCTCTGATAGCCAGCTCAGCTCCTAATCCTTGAGGCAACATTCTTTTTCTATTTGAAC
TTCAGTTCTGTCCTTGAATCCCGACTAGATATTTCTTGCCCTCTGGTCTCAGAATTCTCTTGGCTTTTATTCCTTGATCCACTTGCCAGT
TTTATCACTTTACCCTTGTTCCTCATGGCTTCCCATCAAGCCATGGGTATTAGGTGACAGTGTAATTTATTAGATTCTGGTTTTGCCCAA
ATACTGGGCATGCTTTAATAATAACTGAACCATTTCATTATTTGGATAGGCATGGGTACCTTATCAAGCAGATTAAAAGGATATGGTACC
CGTCCTTTAGAAAAGAACAGCTAAAACCTTGTTGTGGATTATGGATTTAGCCTAAAGAAAAATAATCTGGCATAAATTAAGAGTAAGAGA
GAAGATTAATAGAAATTTCACTTCACATAACTTAAAACATGGCTATTTCAATAAAGGACTAAAGTTTCTCCTGGATCCCAGAATTCAACC
TGTATTTATAAATGTATAATGTATTTAGCTACTTTTTGGTTTAAATGAACTTGTTGGGTTAGCTTGGTAAATGTTATAATTTTTACTATT
TTCTACAAAGAAAATATTTTCTAATTTAAGTTGGAGCTATCTGTGCAGCAGTTTCTCTACAGTTGTGCATAAATGTTTTTACTATAAAAT

>13517_13517_1_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000265872_DDX21_chr10_70723046_ENST00000354185_length(amino acids)=605AA_BP=18
MAQFGGQKNPPWATQFTATAVSQPGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAP
TRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS
VAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETK
KEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCI
CFYQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRS
LINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPR

--------------------------------------------------------------
>13517_13517_2_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000535016_DDX21_chr10_70723046_ENST00000354185_length(transcript)=4198nt_BP=192nt
GAAGTTGGCGCATGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGATCGATGCTATAGAAGACAAA
CAAGGGAAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAG
TATCACAGCCAGGCCGAGGAGTGACCTTCCTATTTCCTATACAAGCAAAGACATTCCATCATGTTTACAGCGGGAAGGACTTAATTGCAC
AGGCACGGACAGGAACTGGGAAGACATTCTCCTTTGCCATCCCTTTGATTGAGAAACTTCATGGGGAACTGCAAGACAGGAAGAGAGGCC
GTGCCCCTCAGGTACTGGTTCTTGCACCTACAAGAGAGTTGGCAAATCAAGTAAGCAAAGACTTCAGTGACATCACAAAAAAGCTGTCAG
TGGCTTGTTTTTATGGTGGAACTCCCTATGGAGGTCAATTTGAACGCATGAGGAATGGGATTGATATCCTGGTTGGAACACCAGGTCGTA
TCAAAGACCACATACAGAATGGCAAACTAGATCTCACCAAACTTAAGCATGTTGTCCTGGATGAAGTGGACCAGATGTTGGATATGGGAT
TTGCTGATCAAGTGGAAGAGATTTTAAGTGTGGCATACAAGAAAGATTCTGAAGACAATCCCCAAACATTGCTTTTTTCTGCAACTTGCC
CTCATTGGGTATTTAATGTTGCCAAGAAATACATGAAATCTACATATGAACAGGTGGACCTGATTGGTAAAAAGACTCAGAAAACGGCAA
TAACTGTGGAGCATCTGGCTATTAAGTGCCACTGGACTCAGAGGGCAGCAGTTATTGGGGATGTCATCCGAGTATATAGTGGTCATCAAG
GACGCACTATCATCTTTTGTGAAACCAAGAAAGAAGCCCAGGAGCTGTCCCAGAATTCAGCTATAAAGCAGGATGCTCAGTCCTTGCATG
GAGACATTCCACAGAAGCAAAGGGAAATCACCCTGAAAGGTTTTAGAAATGGTAGTTTTGGAGTTTTGGTGGCAACCAATGTTGCTGCAC
GTGGGTTAGACATCCCTGAGGTTGATTTGGTTATACAAAGCTCTCCACCAAAGGATGTAGAGTCCTACATTCATCGATCCGGGCGGACAG
GCAGAGCTGGAAGGACGGGGGTGTGCATCTGCTTTTATCAGCACAAGGAAGAATATCAGTTAGTACAAGTGGAGCAAAAAGCGGGAATTA
AGTTCAAACGAATAGGTGTTCCTTCTGCAACAGAAATAATAAAAGCTTCCAGCAAAGATGCCATCAGGCTTTTGGATTCCGTGCCTCCCA
CTGCCATTAGTCACTTCAAACAATCAGCTGAGAAGCTGATAGAGGAGAAGGGAGCTGTGGAAGCTCTGGCAGCAGCACTGGCCCATATTT
CAGGTGCCACGTCCGTAGACCAGCGCTCCTTGATCAACTCAAATGTGGGTTTTGTGACCATGATCTTGCAGTGCTCAATTGAAATGCCAA
ATATTAGTTATGCTTGGAAAGAACTTAAAGAGCAGCTGGGCGAGGAGATTGATTCCAAAGTGAAGGGAATGGTTTTTCTCAAAGGAAAGC
TGGGTGTTTGCTTTGATGTACCTACCGCATCAGTAACAGAAATACAGGAGAAATGGCATGATTCACGACGCTGGCAGCTCTCTGTGGCCA
CAGAGCAACCAGAACTGGAAGGACCACGGGAAGGATATGGAGGCTTCAGGGGACAGCGGGAAGGCAGTCGAGGCTTCAGGGGACAGCGGG
ACGGAAACAGAAGATTCAGAGGACAGCGGGAAGGCAGTAGAGGCCCGAGAGGACAGCGATCAGGAGGTGGCAACAAAAGTAACAGATCCC
AAAACAAAGGCCAGAAGCGGAGTTTCAGTAAAGCATTTGGTCAATAATTAGAAATAGAAGATTTATATAGCAAAAAGAGAATGATGTTTG
GCAATATAGAACTGAACATTATTTTTCATGCAAAGTTAAAAGCACATTGTGCCTCCTTTTGACCACTTGCCAAGTCCCTGTCTCTTTCAG
ACACAGACAAGCTTCATTTAAATTATTTCATCTGATCATTATCATTTATAACTTTATTGTTACTTCTTCATCAGTTTTTCCTTTTGAAAG
GTGTATGAATTCATTACATTTTTATTCTAATGTATTATCTGTAGATTAGAAGATAAAATCAAGCATGTATCTGCCTATACTTTGTGAGTT
CACCTGTCTTTATACTCAAAAGTGTCCCTTAATAGTGTCCTTCCCTGAAATAAATACCTAAGGGAGTGTAACAGTCTCTGGAGGACCACT
TTGAGCCTTTGGAAGTTAAGGTTTCCTCAGCCACCTGCCGAACAGTTTCTCATGTGGTCCTATTATTTGTCTACTGAGACTTAATACTGA
GCAATGTTTTGAAACAAGATTTCAAACTAATCTGGGTTGTAATACAGTTTATACCAGTGTATGCTCTAGACTTGGAAGATGTAGTATGTT
TGATGTGGATTACCTATACTTATGTTCGTTTTGATACATTTTTAGCTTCTCATTATAAGGTGATTCATGCTTTAGTGAATTCTTCATAGA
TAGTATATATAAAAGTACATTTTAATAGAAAGCCAGGGTTTTAAGGAATTTCACATGTATAAGGTGGCTCCATAGCTTTATTTGTAAGTA
GGCTGGATAAATGGTGCTTAAATGGTAATGTACTCCACTTCTTCCTATTGGAAGATTAACATTATTTACCAAGAAGGACTTAAGGGAGTA
GGGGGCGCAGATTAGCATTGCTCAAGAGTATGTAAAAAAAAAAAAAAAAAAAAAGAACCAAACCACTGGAAATAATCAAATGCAAAAAGG
TAACAAATTCATAACTGGAAAGCAAAGAGAAGAACAAGTATGATTTGGATGATAAAGCATTGTTTTAATGGTGAAAACTTCACAGATCAC
TAATGTTTCTAGAGGTTAACTTCAAGTGGGCAAGCTGGGGTTTTTAGGTAGTCAGTGGCCTAGTTCCTAAAGCCACAGTATAGGATCTGT
TAAACTGAATGTCTGTTGAAAGTTTGTTTTAGCTGCTTGGAGGCTTCCTTTTAAGACAAACTGTATGTGATTAAGTTGTTTTGAGGGAAC
TGAAGAACCTGATGTAGCCCCTGGCCAGATAACTGCCTGATTTCTCAGATATTATTTCTCTGGGAAACATTCTACATAGCACAGGAGCTT
AAGAGTGGCATTATCTTCTCGCCTTAATTTCCAGAGATTATTTCTGTACTGAGAATCCTGGAACTACTATGCTAGGAAATTTAAAGCTGC
ATGGTCTGTCTTGTTTTCATTTAATTATTGTGAATACCTAGAATCTTTCTTGGTCCTGATTTCTCTTGCTTAATCCAGTCTTTATCTCTA
ACTGCCCCTTATTTGATCACCATGTACTAGGAGCTCTGATAGCCAGCTCAGCTCCTAATCCTTGAGGCAACATTCTTTTTCTATTTGAAC
TTCAGTTCTGTCCTTGAATCCCGACTAGATATTTCTTGCCCTCTGGTCTCAGAATTCTCTTGGCTTTTATTCCTTGATCCACTTGCCAGT
TTTATCACTTTACCCTTGTTCCTCATGGCTTCCCATCAAGCCATGGGTATTAGGTGACAGTGTAATTTATTAGATTCTGGTTTTGCCCAA
ATACTGGGCATGCTTTAATAATAACTGAACCATTTCATTATTTGGATAGGCATGGGTACCTTATCAAGCAGATTAAAAGGATATGGTACC
CGTCCTTTAGAAAAGAACAGCTAAAACCTTGTTGTGGATTATGGATTTAGCCTAAAGAAAAATAATCTGGCATAAATTAAGAGTAAGAGA
GAAGATTAATAGAAATTTCACTTCACATAACTTAAAACATGGCTATTTCAATAAAGGACTAAAGTTTCTCCTGGATCCCAGAATTCAACC
TGTATTTATAAATGTATAATGTATTTAGCTACTTTTTGGTTTAAATGAACTTGTTGGGTTAGCTTGGTAAATGTTATAATTTTTACTATT
TTCTACAAAGAAAATATTTTCTAATTTAAGTTGGAGCTATCTGTGCAGCAGTTTCTCTACAGTTGTGCATAAATGTTTTTACTATAAAAT

>13517_13517_2_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000535016_DDX21_chr10_70723046_ENST00000354185_length(amino acids)=605AA_BP=18
MAQFGGQKNPPWATQFTATAVSQPGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAP
TRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS
VAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETK
KEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCI
CFYQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRS
LINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPR

--------------------------------------------------------------
>13517_13517_3_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000543719_DDX21_chr10_70723046_ENST00000354185_length(transcript)=4192nt_BP=186nt
TGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGGTGAAGATCGATGCTATAGAAGACAAACAAGGG
AAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAGTATCAC
AGCCAGGCCGAGGAGTGACCTTCCTATTTCCTATACAAGCAAAGACATTCCATCATGTTTACAGCGGGAAGGACTTAATTGCACAGGCAC
GGACAGGAACTGGGAAGACATTCTCCTTTGCCATCCCTTTGATTGAGAAACTTCATGGGGAACTGCAAGACAGGAAGAGAGGCCGTGCCC
CTCAGGTACTGGTTCTTGCACCTACAAGAGAGTTGGCAAATCAAGTAAGCAAAGACTTCAGTGACATCACAAAAAAGCTGTCAGTGGCTT
GTTTTTATGGTGGAACTCCCTATGGAGGTCAATTTGAACGCATGAGGAATGGGATTGATATCCTGGTTGGAACACCAGGTCGTATCAAAG
ACCACATACAGAATGGCAAACTAGATCTCACCAAACTTAAGCATGTTGTCCTGGATGAAGTGGACCAGATGTTGGATATGGGATTTGCTG
ATCAAGTGGAAGAGATTTTAAGTGTGGCATACAAGAAAGATTCTGAAGACAATCCCCAAACATTGCTTTTTTCTGCAACTTGCCCTCATT
GGGTATTTAATGTTGCCAAGAAATACATGAAATCTACATATGAACAGGTGGACCTGATTGGTAAAAAGACTCAGAAAACGGCAATAACTG
TGGAGCATCTGGCTATTAAGTGCCACTGGACTCAGAGGGCAGCAGTTATTGGGGATGTCATCCGAGTATATAGTGGTCATCAAGGACGCA
CTATCATCTTTTGTGAAACCAAGAAAGAAGCCCAGGAGCTGTCCCAGAATTCAGCTATAAAGCAGGATGCTCAGTCCTTGCATGGAGACA
TTCCACAGAAGCAAAGGGAAATCACCCTGAAAGGTTTTAGAAATGGTAGTTTTGGAGTTTTGGTGGCAACCAATGTTGCTGCACGTGGGT
TAGACATCCCTGAGGTTGATTTGGTTATACAAAGCTCTCCACCAAAGGATGTAGAGTCCTACATTCATCGATCCGGGCGGACAGGCAGAG
CTGGAAGGACGGGGGTGTGCATCTGCTTTTATCAGCACAAGGAAGAATATCAGTTAGTACAAGTGGAGCAAAAAGCGGGAATTAAGTTCA
AACGAATAGGTGTTCCTTCTGCAACAGAAATAATAAAAGCTTCCAGCAAAGATGCCATCAGGCTTTTGGATTCCGTGCCTCCCACTGCCA
TTAGTCACTTCAAACAATCAGCTGAGAAGCTGATAGAGGAGAAGGGAGCTGTGGAAGCTCTGGCAGCAGCACTGGCCCATATTTCAGGTG
CCACGTCCGTAGACCAGCGCTCCTTGATCAACTCAAATGTGGGTTTTGTGACCATGATCTTGCAGTGCTCAATTGAAATGCCAAATATTA
GTTATGCTTGGAAAGAACTTAAAGAGCAGCTGGGCGAGGAGATTGATTCCAAAGTGAAGGGAATGGTTTTTCTCAAAGGAAAGCTGGGTG
TTTGCTTTGATGTACCTACCGCATCAGTAACAGAAATACAGGAGAAATGGCATGATTCACGACGCTGGCAGCTCTCTGTGGCCACAGAGC
AACCAGAACTGGAAGGACCACGGGAAGGATATGGAGGCTTCAGGGGACAGCGGGAAGGCAGTCGAGGCTTCAGGGGACAGCGGGACGGAA
ACAGAAGATTCAGAGGACAGCGGGAAGGCAGTAGAGGCCCGAGAGGACAGCGATCAGGAGGTGGCAACAAAAGTAACAGATCCCAAAACA
AAGGCCAGAAGCGGAGTTTCAGTAAAGCATTTGGTCAATAATTAGAAATAGAAGATTTATATAGCAAAAAGAGAATGATGTTTGGCAATA
TAGAACTGAACATTATTTTTCATGCAAAGTTAAAAGCACATTGTGCCTCCTTTTGACCACTTGCCAAGTCCCTGTCTCTTTCAGACACAG
ACAAGCTTCATTTAAATTATTTCATCTGATCATTATCATTTATAACTTTATTGTTACTTCTTCATCAGTTTTTCCTTTTGAAAGGTGTAT
GAATTCATTACATTTTTATTCTAATGTATTATCTGTAGATTAGAAGATAAAATCAAGCATGTATCTGCCTATACTTTGTGAGTTCACCTG
TCTTTATACTCAAAAGTGTCCCTTAATAGTGTCCTTCCCTGAAATAAATACCTAAGGGAGTGTAACAGTCTCTGGAGGACCACTTTGAGC
CTTTGGAAGTTAAGGTTTCCTCAGCCACCTGCCGAACAGTTTCTCATGTGGTCCTATTATTTGTCTACTGAGACTTAATACTGAGCAATG
TTTTGAAACAAGATTTCAAACTAATCTGGGTTGTAATACAGTTTATACCAGTGTATGCTCTAGACTTGGAAGATGTAGTATGTTTGATGT
GGATTACCTATACTTATGTTCGTTTTGATACATTTTTAGCTTCTCATTATAAGGTGATTCATGCTTTAGTGAATTCTTCATAGATAGTAT
ATATAAAAGTACATTTTAATAGAAAGCCAGGGTTTTAAGGAATTTCACATGTATAAGGTGGCTCCATAGCTTTATTTGTAAGTAGGCTGG
ATAAATGGTGCTTAAATGGTAATGTACTCCACTTCTTCCTATTGGAAGATTAACATTATTTACCAAGAAGGACTTAAGGGAGTAGGGGGC
GCAGATTAGCATTGCTCAAGAGTATGTAAAAAAAAAAAAAAAAAAAAAGAACCAAACCACTGGAAATAATCAAATGCAAAAAGGTAACAA
ATTCATAACTGGAAAGCAAAGAGAAGAACAAGTATGATTTGGATGATAAAGCATTGTTTTAATGGTGAAAACTTCACAGATCACTAATGT
TTCTAGAGGTTAACTTCAAGTGGGCAAGCTGGGGTTTTTAGGTAGTCAGTGGCCTAGTTCCTAAAGCCACAGTATAGGATCTGTTAAACT
GAATGTCTGTTGAAAGTTTGTTTTAGCTGCTTGGAGGCTTCCTTTTAAGACAAACTGTATGTGATTAAGTTGTTTTGAGGGAACTGAAGA
ACCTGATGTAGCCCCTGGCCAGATAACTGCCTGATTTCTCAGATATTATTTCTCTGGGAAACATTCTACATAGCACAGGAGCTTAAGAGT
GGCATTATCTTCTCGCCTTAATTTCCAGAGATTATTTCTGTACTGAGAATCCTGGAACTACTATGCTAGGAAATTTAAAGCTGCATGGTC
TGTCTTGTTTTCATTTAATTATTGTGAATACCTAGAATCTTTCTTGGTCCTGATTTCTCTTGCTTAATCCAGTCTTTATCTCTAACTGCC
CCTTATTTGATCACCATGTACTAGGAGCTCTGATAGCCAGCTCAGCTCCTAATCCTTGAGGCAACATTCTTTTTCTATTTGAACTTCAGT
TCTGTCCTTGAATCCCGACTAGATATTTCTTGCCCTCTGGTCTCAGAATTCTCTTGGCTTTTATTCCTTGATCCACTTGCCAGTTTTATC
ACTTTACCCTTGTTCCTCATGGCTTCCCATCAAGCCATGGGTATTAGGTGACAGTGTAATTTATTAGATTCTGGTTTTGCCCAAATACTG
GGCATGCTTTAATAATAACTGAACCATTTCATTATTTGGATAGGCATGGGTACCTTATCAAGCAGATTAAAAGGATATGGTACCCGTCCT
TTAGAAAAGAACAGCTAAAACCTTGTTGTGGATTATGGATTTAGCCTAAAGAAAAATAATCTGGCATAAATTAAGAGTAAGAGAGAAGAT
TAATAGAAATTTCACTTCACATAACTTAAAACATGGCTATTTCAATAAAGGACTAAAGTTTCTCCTGGATCCCAGAATTCAACCTGTATT
TATAAATGTATAATGTATTTAGCTACTTTTTGGTTTAAATGAACTTGTTGGGTTAGCTTGGTAAATGTTATAATTTTTACTATTTTCTAC
AAAGAAAATATTTTCTAATTTAAGTTGGAGCTATCTGTGCAGCAGTTTCTCTACAGTTGTGCATAAATGTTTTTACTATAAAATGAGCTA

>13517_13517_3_CCAR1-DDX21_CCAR1_chr10_70482334_ENST00000543719_DDX21_chr10_70723046_ENST00000354185_length(amino acids)=605AA_BP=18
MAQFGGQKNPPWATQFTATAVSQPGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAP
TRELANQVSKDFSDITKKLSVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS
VAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIFCETK
KEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCI
CFYQHKEEYQLVQVEQKAGIKFKRIGVPSATEIIKASSKDAIRLLDSVPPTAISHFKQSAEKLIEEKGAVEALAAALAHISGATSVDQRS
LINSNVGFVTMILQCSIEMPNISYAWKELKEQLGEEIDSKVKGMVFLKGKLGVCFDVPTASVTEIQEKWHDSRRWQLSVATEQPELEGPR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CCAR1-DDX21

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000265872	+	2	25	1_249	24.333333333333332	1151.0	AR
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000535016	+	2	24	1_249	24.333333333333332	1136.0	AR
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000543719	+	2	24	1_249	24.333333333333332	1136.0	AR
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000265872	+	2	25	643_1150	24.333333333333332	1151.0	GATA1
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000535016	+	2	24	643_1150	24.333333333333332	1136.0	GATA1
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000543719	+	2	24	643_1150	24.333333333333332	1136.0	GATA1
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000265872	+	2	25	203_660	24.333333333333332	1151.0	GATA2
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000535016	+	2	24	203_660	24.333333333333332	1136.0	GATA2
Hgene	CCAR1	chr10:70482334	chr10:70723046	ENST00000543719	+	2	24	203_660	24.333333333333332	1136.0	GATA2

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CCAR1-DDX21

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CCAR1-DDX21

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source