FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CCDC107-PITPNB (FusionGDB2 ID:13571)

Fusion Gene Summary for CCDC107-PITPNB

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC107-PITPNB
Fusion gene ID: 13571
HgeneTgene
Gene symbol

CCDC107

PITPNB

Gene ID

203260

23760

Gene namecoiled-coil domain containing 107phosphatidylinositol transfer protein beta
SynonymsPSEC0222PI-TP-beta|PtdInsTP|VIB1B
Cytomap

9p13.3

22q12.1

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 107phosphatidylinositol transfer protein beta isoformPtdIns transfer protein betaphosphotidylinositol transfer protein, beta
Modification date2020031320200313
UniProtAcc

Q8WV48

.
Ensembl transtripts involved in fusion geneENST00000421582, ENST00000327351, 
ENST00000378406, ENST00000378407, 
ENST00000378409, ENST00000426546, 
ENST00000320996, ENST00000335272, 
ENST00000455418, 
Fusion gene scores* DoF score1 X 1 X 1=17 X 8 X 7=392
# samples 110
** MAII scorelog2(1/1*10)=3.32192809488736log2(10/392*10)=-1.97085365434048
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCDC107 [Title/Abstract] AND PITPNB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC107(35660644)-PITPNB(28310335), # samples:1
Anticipated loss of major functional domain due to fusion event.CCDC107-PITPNB seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePITPNB

GO:0015914

phospholipid transport

16274224


check buttonFusion gene breakpoints across CCDC107 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PITPNB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-19-2625-01ACCDC107chr9

35660644

+PITPNBchr22

28310335

-


Top

Fusion Gene ORF analysis for CCDC107-PITPNB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000421582ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-
3UTR-3CDSENST00000421582ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
3UTR-3CDSENST00000421582ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000327351ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000327351ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378406ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378406ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378407ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378407ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378409ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000378409ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000426546ENST00000335272CCDC107chr9

35660644

+PITPNBchr22

28310335

-
Frame-shiftENST00000426546ENST00000455418CCDC107chr9

35660644

+PITPNBchr22

28310335

-
In-frameENST00000327351ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-
In-frameENST00000378406ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-
In-frameENST00000378407ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-
In-frameENST00000378409ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-
In-frameENST00000426546ENST00000320996CCDC107chr9

35660644

+PITPNBchr22

28310335

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000378407CCDC107chr935660644+ENST00000320996PITPNBchr2228310335-322848671284425
ENST00000378406CCDC107chr935660644+ENST00000320996PITPNBchr2228310335-36679259351723262
ENST00000426546CCDC107chr935660644+ENST00000320996PITPNBchr2228310335-3218476661274402
ENST00000327351CCDC107chr935660644+ENST00000320996PITPNBchr2228310335-3215473631271402
ENST00000378409CCDC107chr935660644+ENST00000320996PITPNBchr2228310335-315241001208402

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000378407ENST00000320996CCDC107chr935660644+PITPNBchr2228310335-0.0001509360.9998491
ENST00000378406ENST00000320996CCDC107chr935660644+PITPNBchr2228310335-0.0020739290.997926
ENST00000426546ENST00000320996CCDC107chr935660644+PITPNBchr2228310335-0.0001514310.9998486
ENST00000327351ENST00000320996CCDC107chr935660644+PITPNBchr2228310335-0.0001509840.99984896
ENST00000378409ENST00000320996CCDC107chr935660644+PITPNBchr2228310335-0.0001455670.99985445

Top

Fusion Genomic Features for CCDC107-PITPNB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CCDC107-PITPNB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:35660644/chr22:28310335)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CCDC107

Q8WV48

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC107chr9:35660644chr22:28310335ENST00000327351+46104_134136179.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC107chr9:35660644chr22:28310335ENST00000378407+45104_134136140.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC107chr9:35660644chr22:28310335ENST00000378409+46104_134136257.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC107chr9:35660644chr22:28310335ENST00000426546+45104_134136284.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC107chr9:35660644chr22:28310335ENST00000327351+4665_85136179.0TransmembraneHelical
HgeneCCDC107chr9:35660644chr22:28310335ENST00000378407+4565_85136140.0TransmembraneHelical
HgeneCCDC107chr9:35660644chr22:28310335ENST00000378409+4665_85136257.0TransmembraneHelical
HgeneCCDC107chr9:35660644chr22:28310335ENST00000426546+4565_85136284.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC107chr9:35660644chr22:28310335ENST00000421582+13104_1340120.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC107chr9:35660644chr22:28310335ENST00000421582+1365_850120.0TransmembraneHelical


Top

Fusion Gene Sequence for CCDC107-PITPNB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13571_13571_1_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000327351_PITPNB_chr22_28310335_ENST00000320996_length(transcript)=3215nt_BP=473nt
CGGCCGGCCAATGCCGGACCGCTTCGGCACCGCCCGCCCGATCCCTCCACCCGTGGGCCGGCAATGGCGGGCGCAGTTTCGCTCTTGGGT
GTGGTGGGGCTGCTGCTTGTGTCTGCGCTGTCCGGGGTCCTAGGAGACCGCGCCAATCCCGACCTCCGGGCACACCCAGGGAACGCAGCC
CACCCCGGCTCTGGAGCCACGGAACCCCGGCGGCGACCACCGCTCAAGGATCAACGCGAGCGGACCCGGGCCGGGTCGCTGCCTCTGGGG
GCGCTGTACACCGCGGCCGTCGCGGCTTTTGTGCTGTACAAGTGTTTGCAGGGGAAAGATGAAACTGCGGTTCTCCACGAGGAGGCAAGC
AAGCAGCAGCCACTGCAGTCAGAGCAACAGCTGGCCCAGTTGACACAACAGCTGGCCCAGACAGAGCAGCACCTGAACAACCTGATGGCC
CAGCTGGACCCCCTTTTTGAGCGCCGTGTGGTTTTGCCATGTTCTGTTCAGGAGTATCAGGTTGGGCAGCTTTACTCTGTTGCAGAAGCT
AGTAAGAATGAGACTGGTGGTGGAGAAGGAATTGAAGTCTTAAAGAATGAACCTTATGAGAAGGATGGAGAAAAGGGACAGTATACGCAC
AAAATTTATCACCTAAAGAGCAAAGTGCCTGCATTCGTGAGGATGATTGCTCCCGAGGGCTCCTTGGTGTTTCATGAGAAAGCCTGGAAT
GCGTACCCCTACTGTAGAACAATTGTAACGAATGAATATATGAAAGATGATTTCTTCATTAAAATCGAAACATGGCACAAACCAGACTTG
GGAACATTAGAAAATGTACATGGTTTAGATCCAAACACATGGAAAACTGTTGAAATTGTCCATATAGATATTGCAGATAGAAGTCAAGTT
GAACCAGCAGACTACAAAGCTGATGAAGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGAAG
GAGCTGGCAAACAGCCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAGTA
GAAAACTTCATTCAAAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCACG
ATGGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAGCC
AGTGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAGGT
TCTCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACACT
TGTGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGAAA
ATATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAGCT
GGTATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTTTT
TTTTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATGTA
TTTATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTACT
TGTTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACATCA
AACCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAAGA
AATTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTGTA
ACTACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTGTG
GGAACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAGGC
CCCGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGAGT
GCTGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAGCT
TTCTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCTTT
TGTAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTGCT
CCTCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGCAT
TGCAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGGCA
CTGTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAAGA
GTCTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCGGC
GCATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCTTG

>13571_13571_1_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000327351_PITPNB_chr22_28310335_ENST00000320996_length(amino acids)=402AA_BP=137
MAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLPLGALYTAAVAAFVLYKCLQGKDE
TAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEK
DGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVH
IDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNFHRQLFC

--------------------------------------------------------------
>13571_13571_2_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378406_PITPNB_chr22_28310335_ENST00000320996_length(transcript)=3667nt_BP=925nt
GGGCGGCCGGCCAATGCCGGACCGCTTCGGCACCGCCCGCCCGATCCCTCCACCCGTGGGCCGGCAATGGCGGGCGCAGTTTCGCTCTTG
GGTGTGGTGGGGCTGCTGCTTGTGTCTGCGCTGTCCGGGGTCCTAGGAGACCGCGCCAATCCCGACCTCCGGGCACACCCAGGGAACGCA
GCCCACCCCGGCTCTGGAGCCACGGAACCCCGGCGGCGACCACCGCTCAAGGATCAACGCGAGCGGACCCGGGCCGGGTCGCTGCCTCTG
GGGGCGCTGTACACCGCGGCCGTCGCGGCTTTTGTGCTGTACAAGTGTTTGCAGGGGAAAGATGAAACTGCGGTTCTCCACGAGGAGGCA
AGCAAGCAGCAGCCACTGCAGTCAGGTGAGGAGAGCAATGATTCTGTGAATTTTTGGGGAATTTGTGGCAGGAGGGAGGAATGGGGACAT
AGGTTGGGAGCCACTGAGTGGACATTTCTTCAGTGTGACTACTCTGGCTGGAGCCCAGCAGGAGCTTCTGAACATGAAGCTATGGACCAT
CCACGAGCTGCTGCAAGATAGCAAGCCGGACAAGGATATGGAGGCTTCAGAACCAGGTGAAGGCTCGGGAGGCGAGTCTGCTGGAGGTGG
AGACAAAGTCTCTGAAACTGGAACATTCCTGATCTCTCCCCACACAGAGGCCAGCAGACCTCTTCCTGAGGACTTCTGTTTAAAGGAGGA
CGAGGAGGAGATTGGTGACAGTCAGGCCTGGGAGGAGCCCACAAACTGGAGCACAGAGACATGGAACCTAGCTACTTCCTGGGAGGTGGG
GCGGGGACTACGGAGAAGGTGCAGCCAGGCTGTGGCAAAGGGCCCCAGTCACAGCCTTGGCTGGGAAGGAGGGACGACAGCTGAAGGTCG
ACTAAAACAAAGTCTGTTTTCATGACCGTGTGGTTTTGCCATGTTCTGTTCAGGAGTATCAGGTTGGGCAGCTTTACTCTGTTGCAGAAG
CTAGTAAGAATGAGACTGGTGGTGGAGAAGGAATTGAAGTCTTAAAGAATGAACCTTATGAGAAGGATGGAGAAAAGGGACAGTATACGC
ACAAAATTTATCACCTAAAGAGCAAAGTGCCTGCATTCGTGAGGATGATTGCTCCCGAGGGCTCCTTGGTGTTTCATGAGAAAGCCTGGA
ATGCGTACCCCTACTGTAGAACAATTGTAACGAATGAATATATGAAAGATGATTTCTTCATTAAAATCGAAACATGGCACAAACCAGACT
TGGGAACATTAGAAAATGTACATGGTTTAGATCCAAACACATGGAAAACTGTTGAAATTGTCCATATAGATATTGCAGATAGAAGTCAAG
TTGAACCAGCAGACTACAAAGCTGATGAAGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAGA
AGGAGCTGGCAAACAGCCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAAG
TAGAAAACTTCATTCAAAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTCA
CGATGGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCAG
CCAGTGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACAG
GTTCTCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACACA
CTTGTGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAGA
AAATATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTAG
CTGGTATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATTT
TTTTTTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAATG
TATTTATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTTA
CTTGTTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACAT
CAAACCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGAA
GAAATTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCTG
TAACTACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTTG
TGGGAACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGAG
GCCCCGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAGA
GTGCTGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCAG
CTTTCTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTCT
TTTGTAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCTG
CTCCTCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTGC
ATTGCAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGGG
CACTGTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAAA
GAGTCTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCCG
GCGCATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTCT

>13571_13571_2_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378406_PITPNB_chr22_28310335_ENST00000320996_length(amino acids)=262AA_BP=
MPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEKDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTN
EYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQM

--------------------------------------------------------------
>13571_13571_3_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378407_PITPNB_chr22_28310335_ENST00000320996_length(transcript)=3228nt_BP=486nt
GTGCGCGTTGGGGCGGCCGGCCAATGCCGGACCGCTTCGGCACCGCCCGCCCGATCCCTCCACCCGTGGGCCGGCAATGGCGGGCGCAGT
TTCGCTCTTGGGTGTGGTGGGGCTGCTGCTTGTGTCTGCGCTGTCCGGGGTCCTAGGAGACCGCGCCAATCCCGACCTCCGGGCACACCC
AGGGAACGCAGCCCACCCCGGCTCTGGAGCCACGGAACCCCGGCGGCGACCACCGCTCAAGGATCAACGCGAGCGGACCCGGGCCGGGTC
GCTGCCTCTGGGGGCGCTGTACACCGCGGCCGTCGCGGCTTTTGTGCTGTACAAGTGTTTGCAGGGGAAAGATGAAACTGCGGTTCTCCA
CGAGGAGGCAAGCAAGCAGCAGCCACTGCAGTCAGAGCAACAGCTGGCCCAGTTGACACAACAGCTGGCCCAGACAGAGCAGCACCTGAA
CAACCTGATGGCCCAGCTGGACCCCCTTTTTGAGCGCCGTGTGGTTTTGCCATGTTCTGTTCAGGAGTATCAGGTTGGGCAGCTTTACTC
TGTTGCAGAAGCTAGTAAGAATGAGACTGGTGGTGGAGAAGGAATTGAAGTCTTAAAGAATGAACCTTATGAGAAGGATGGAGAAAAGGG
ACAGTATACGCACAAAATTTATCACCTAAAGAGCAAAGTGCCTGCATTCGTGAGGATGATTGCTCCCGAGGGCTCCTTGGTGTTTCATGA
GAAAGCCTGGAATGCGTACCCCTACTGTAGAACAATTGTAACGAATGAATATATGAAAGATGATTTCTTCATTAAAATCGAAACATGGCA
CAAACCAGACTTGGGAACATTAGAAAATGTACATGGTTTAGATCCAAACACATGGAAAACTGTTGAAATTGTCCATATAGATATTGCAGA
TAGAAGTCAAGTTGAACCAGCAGACTACAAAGCTGATGAAGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACC
CAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACT
GCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTG
GATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGG
AACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACA
CACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCC
AGATACACACACTTGTGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAG
AATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAA
TGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCT
GTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTA
AACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAG
GCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATA
TTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAAC
ACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATG
ACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTT
TGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGT
GCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAG
GCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAG
ATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTC
ACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCC
TGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGG
ATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTT
TACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTT
TGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAA
ATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACT

>13571_13571_3_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378407_PITPNB_chr22_28310335_ENST00000320996_length(amino acids)=425AA_BP=160
MGRPANAGPLRHRPPDPSTRGPAMAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLP
LGALYTAAVAAFVLYKCLQGKDETAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERRVVLPCSVQEYQVGQLYSVA
EASKNETGGGEGIEVLKNEPYEKDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKP
DLGTLENVHGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQMCAYKLVTIKFKWWGLQS

--------------------------------------------------------------
>13571_13571_4_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378409_PITPNB_chr22_28310335_ENST00000320996_length(transcript)=3152nt_BP=410nt
ATGGCGGGCGCAGTTTCGCTCTTGGGTGTGGTGGGGCTGCTGCTTGTGTCTGCGCTGTCCGGGGTCCTAGGAGACCGCGCCAATCCCGAC
CTCCGGGCACACCCAGGGAACGCAGCCCACCCCGGCTCTGGAGCCACGGAACCCCGGCGGCGACCACCGCTCAAGGATCAACGCGAGCGG
ACCCGGGCCGGGTCGCTGCCTCTGGGGGCGCTGTACACCGCGGCCGTCGCGGCTTTTGTGCTGTACAAGTGTTTGCAGGGGAAAGATGAA
ACTGCGGTTCTCCACGAGGAGGCAAGCAAGCAGCAGCCACTGCAGTCAGAGCAACAGCTGGCCCAGTTGACACAACAGCTGGCCCAGACA
GAGCAGCACCTGAACAACCTGATGGCCCAGCTGGACCCCCTTTTTGAGCGCCGTGTGGTTTTGCCATGTTCTGTTCAGGAGTATCAGGTT
GGGCAGCTTTACTCTGTTGCAGAAGCTAGTAAGAATGAGACTGGTGGTGGAGAAGGAATTGAAGTCTTAAAGAATGAACCTTATGAGAAG
GATGGAGAAAAGGGACAGTATACGCACAAAATTTATCACCTAAAGAGCAAAGTGCCTGCATTCGTGAGGATGATTGCTCCCGAGGGCTCC
TTGGTGTTTCATGAGAAAGCCTGGAATGCGTACCCCTACTGTAGAACAATTGTAACGAATGAATATATGAAAGATGATTTCTTCATTAAA
ATCGAAACATGGCACAAACCAGACTTGGGAACATTAGAAAATGTACATGGTTTAGATCCAAACACATGGAAAACTGTTGAAATTGTCCAT
ATAGATATTGCAGATAGAAGTCAAGTTGAACCAGCAGACTACAAAGCTGATGAAGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGA
GGCCCTTTGGGACCCAACTGGAAGAAGGAGCTGGCAAACAGCCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTC
AAGTGGTGGGGACTGCAAAGCAAAGTAGAAAACTTCATTCAAAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGT
TGGATTGACAAGTGGATCGATCTCACGATGGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAA
GGTCAAGTGAGGGGAACAAGCGCAGCCAGTGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCT
TGTGATGATACACACACATGCACAGGTTCTCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGT
AGAGCTACAGATCCAGATACACACACTTGTGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTAC
CTATCTTCAGCAAGAATGCAAAAGAAAATATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGA
CAAATTGACTGCAATGTAATACTAGCTGGTATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTC
TTTTAAGTCAGTCTGTTATAAATTTTTTTTTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAAT
GAATCTGGGATGTAAACTCTGAATGTATTTATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAG
GAGCAAAGTTACAGGCCAGTTTTTACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATT
TTAAATTTCAAATATTTTTCTACATCAAACCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCT
CCTGTTAGACAAACACATTGATGAAGAAATTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTC
TTGTTTTGAAGATGACAGTTTTCTGTAACTACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGT
TAGTGATGACATTTTGCTCTTCTTGTGGGAACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTG
AGTCTGGCCTGCGTGCGGTGAGGAGGCCCCGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGA
CAGATTCTGAATAGGCATCATGAGAGTGCTGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAAC
AATAGCTAGGTAAGATTTTTATCAGCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTT
GAAGCCTTCAGGTCACAAACTGTCTTTTGTAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGA
TTTGCTGACAGTCCTGCCCTGCCTGCTCCTCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAG
GAAGGATGTGTAGGATCACTACTGCATTGCAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGA
TAAAGACTGATGTTTACTCTCTGGGCACTGTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAG
ATTATTGCTAATTTTGTGAAATAAAGAGTCTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTT
AGGCGCACATGGAAATGAGAGCCCGGCGCATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAA
ATACCTAGTTTACTTGCCAGTCTCTTGTGTAAATTACAGTAAAACAAAGTAAATGAAATTTAAACAAAAAATAAATTTGATCACAAAATG

>13571_13571_4_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000378409_PITPNB_chr22_28310335_ENST00000320996_length(amino acids)=402AA_BP=137
MAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLPLGALYTAAVAAFVLYKCLQGKDE
TAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEK
DGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVH
IDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNFHRQLFC

--------------------------------------------------------------
>13571_13571_5_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000426546_PITPNB_chr22_28310335_ENST00000320996_length(transcript)=3218nt_BP=476nt
GGGCGGCCGGCCAATGCCGGACCGCTTCGGCACCGCCCGCCCGATCCCTCCACCCGTGGGCCGGCAATGGCGGGCGCAGTTTCGCTCTTG
GGTGTGGTGGGGCTGCTGCTTGTGTCTGCGCTGTCCGGGGTCCTAGGAGACCGCGCCAATCCCGACCTCCGGGCACACCCAGGGAACGCA
GCCCACCCCGGCTCTGGAGCCACGGAACCCCGGCGGCGACCACCGCTCAAGGATCAACGCGAGCGGACCCGGGCCGGGTCGCTGCCTCTG
GGGGCGCTGTACACCGCGGCCGTCGCGGCTTTTGTGCTGTACAAGTGTTTGCAGGGGAAAGATGAAACTGCGGTTCTCCACGAGGAGGCA
AGCAAGCAGCAGCCACTGCAGTCAGAGCAACAGCTGGCCCAGTTGACACAACAGCTGGCCCAGACAGAGCAGCACCTGAACAACCTGATG
GCCCAGCTGGACCCCCTTTTTGAGCGCCGTGTGGTTTTGCCATGTTCTGTTCAGGAGTATCAGGTTGGGCAGCTTTACTCTGTTGCAGAA
GCTAGTAAGAATGAGACTGGTGGTGGAGAAGGAATTGAAGTCTTAAAGAATGAACCTTATGAGAAGGATGGAGAAAAGGGACAGTATACG
CACAAAATTTATCACCTAAAGAGCAAAGTGCCTGCATTCGTGAGGATGATTGCTCCCGAGGGCTCCTTGGTGTTTCATGAGAAAGCCTGG
AATGCGTACCCCTACTGTAGAACAATTGTAACGAATGAATATATGAAAGATGATTTCTTCATTAAAATCGAAACATGGCACAAACCAGAC
TTGGGAACATTAGAAAATGTACATGGTTTAGATCCAAACACATGGAAAACTGTTGAAATTGTCCATATAGATATTGCAGATAGAAGTCAA
GTTGAACCAGCAGACTACAAAGCTGATGAAGACCCAGCATTATTCCAGTCAGTCAAGACCAAGAGAGGCCCTTTGGGACCCAACTGGAAG
AAGGAGCTGGCAAACAGCCCTGACTGTCCCCAGATGTGTGCCTATAAGCTGGTGACCATCAAATTCAAGTGGTGGGGACTGCAAAGCAAA
GTAGAAAACTTCATTCAAAAGCAAGAAAAACGGATATTTACAAACTTCCATCGCCAGCTTTTTTGTTGGATTGACAAGTGGATCGATCTC
ACGATGGAAGACATTAGGAGAATGGAAGACGAGACTCAGAAAGAACTAGAAACATTACGTAATCAAGGTCAAGTGAGGGGAACAAGCGCA
GCCAGTGATGAGTGAAGAAGAATCTGACCAGTATCTTGCAGTGTTGACGTTTCCCAGATGTGTGCTTGTGATGATACACACACATGCACA
GGTTCTCAACCACGTGTGTATATATGTATGTGTGCATATGTCTGTAGCTGTATATAAAGCGCATGTAGAGCTACAGATCCAGATACACAC
ACTTGTGTATATATGTACATACAGACATACTGAAGGGATTAGTACAATTTCTCCAAAGTACTGTACCTATCTTCAGCAAGAATGCAAAAG
AAAATATTTTCAATATATATACCTGGAACAGATTTTAATAATTATCAGAGTAATACCATTAATGGACAAATTGACTGCAATGTAATACTA
GCTGGTATGTTTCATAAATGTCAAGCTGTGGACCAACATATATAGCCTTTTATTATTTTTCTCTTCTTTTAAGTCAGTCTGTTATAAATT
TTTTTTTAGTCCCATAAGCAGTAGACTCCCACAGAAAATTTCTTCAAAATTTTTTGGTGTTCCAATGAATCTGGGATGTAAACTCTGAAT
GTATTTATAACTATTTATTTCTGGATGGTCATTATCTTGTAGCCAAATTTGACAATATAAAGTAAGGAGCAAAGTTACAGGCCAGTTTTT
ACTTGTTTGCCCTGAGGGAAAAATCCTTTTAAAAAAAATTTCTGGTTTTTATTGGATTTTTGTATTTTAAATTTCAAATATTTTTCTACA
TCAAACCTAGCAAAAATGGAGATGACGGTTTCTGATTTATAATAAATACTAGACAGTTTTCAGGCTCCTGTTAGACAAACACATTGATGA
AGAAATTAGTCTTAATAGGATTGTAGGCTGTGTAGAAAAGTTGGAAATATAGCACTTCATGGAGTCTTGTTTTGAAGATGACAGTTTTCT
GTAACTACAGCTTGGAAACTATGCAAATGGTCTAGATTCCTCAGAGCTCACATGATAGGATATAGTTAGTGATGACATTTTGCTCTTCTT
GTGGGAACACACACTTCAAGGAGGAGATAGTGACTTTGAGATAGGAACAGTTTAAGATGCAGTGTGAGTCTGGCCTGCGTGCGGTGAGGA
GGCCCCGCCAAGAGACTGGTGGACATCTGACTGTGGGATGTGCTCTCAAGTAGGACGTCATCAGGACAGATTCTGAATAGGCATCATGAG
AGTGCTGGTCAGAAACGGCTGCCACTTTTTTTAATTTAATTTTATTTTTTATTTAAAGGAAGGAACAATAGCTAGGTAAGATTTTTATCA
GCTTTCTCTGTCTGAATCCAGTTTTTCCTCTGTCAGTCCTGGAAGCTTGAATAGAATTATATTGTTGAAGCCTTCAGGTCACAAACTGTC
TTTTGTAACCTCCTGTCCCTCCTAAAACACGCCAACCCCTGCAGTCAAATCACATTAGTAATCTGATTTGCTGACAGTCCTGCCCTGCCT
GCTCCTCGTTTTCCCACATGTCCTGCATCCCTCCCCCACTGGAGTGATTTCAGTGAATCAGACAAGGAAGGATGTGTAGGATCACTACTG
CATTGCAATACCCTGTTATCCTCAGCAACAAAACCCACATTTCATACATCCTTTGTGTACTCAGGATAAAGACTGATGTTTACTCTCTGG
GCACTGTTGTAAGATAGGTTTTGTCAGAGCATAATCATTGTCTGCAAAGTGTTTGGTGCGAGGAAGATTATTGCTAATTTTGTGAAATAA
AGAGTCTAGCCCTCTCCTTTTAATGAACTTAACTCTCGCTGGCATCTGTAGTATCATTGGGAGCTTAGGCGCACATGGAAATGAGAGCCC
GGCGCATGGATTTTAATGTTTTTCTAACAACTGTGGAGATTTGAGGGAATGTGTGGTGAATGTAAAATACCTAGTTTACTTGCCAGTCTC

>13571_13571_5_CCDC107-PITPNB_CCDC107_chr9_35660644_ENST00000426546_PITPNB_chr22_28310335_ENST00000320996_length(amino acids)=402AA_BP=137
MAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLPLGALYTAAVAAFVLYKCLQGKDE
TAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEK
DGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVH
IDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNFHRQLFC

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CCDC107-PITPNB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CCDC107-PITPNB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CCDC107-PITPNB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource