FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CCDC148-ACTR3 (FusionGDB2 ID:13662)

Fusion Gene Summary for CCDC148-ACTR3

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC148-ACTR3
Fusion gene ID: 13662
HgeneTgene
Gene symbol

CCDC148

ACTR3

Gene ID

130940

10096

Gene namecoiled-coil domain containing 148actin related protein 3
Synonyms-ARP3
Cytomap

2q24.1

2q14.1

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 148actin-related protein 3ARP3 actin related protein 3 homologactin-like protein 3
Modification date2020031320200327
UniProtAcc.

Q9C0K3

Ensembl transtripts involved in fusion geneENST00000491563, ENST00000536771, 
ENST00000283233, ENST00000409889, 
ENST00000409187, 		ENST00000263238, 
ENST00000535589, ENST00000536059, 
Fusion gene scores* DoF score5 X 4 X 4=8016 X 13 X 7=1456
# samples 617
** MAII scorelog2(6/80*10)=-0.415037499278844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1456*10)=-3.098403704061
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCDC148 [Title/Abstract] AND ACTR3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC148(159312927)-ACTR3(114684922), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneACTR3

GO:0034314

Arp2/3 complex-mediated actin nucleation

11741539|17220302

TgeneACTR3

GO:0045944

positive regulation of transcription by RNA polymerase II

17220302


check buttonFusion gene breakpoints across CCDC148 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACTR3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-33-4532-01ACCDC148chr2

159312927

-ACTR3chr2

114684922

+


Top

Fusion Gene ORF analysis for CCDC148-ACTR3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000491563ENST00000263238CCDC148chr2

159312927

-ACTR3chr2

114684922

+
5UTR-3CDSENST00000491563ENST00000535589CCDC148chr2

159312927

-ACTR3chr2

114684922

+
5UTR-3CDSENST00000491563ENST00000536059CCDC148chr2

159312927

-ACTR3chr2

114684922

+
5UTR-3CDSENST00000536771ENST00000263238CCDC148chr2

159312927

-ACTR3chr2

114684922

+
5UTR-3CDSENST00000536771ENST00000535589CCDC148chr2

159312927

-ACTR3chr2

114684922

+
5UTR-3CDSENST00000536771ENST00000536059CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000283233ENST00000263238CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000283233ENST00000535589CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000283233ENST00000536059CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000409889ENST00000263238CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000409889ENST00000535589CCDC148chr2

159312927

-ACTR3chr2

114684922

+
In-frameENST00000409889ENST00000536059CCDC148chr2

159312927

-ACTR3chr2

114684922

+
intron-3CDSENST00000409187ENST00000263238CCDC148chr2

159312927

-ACTR3chr2

114684922

+
intron-3CDSENST00000409187ENST00000535589CCDC148chr2

159312927

-ACTR3chr2

114684922

+
intron-3CDSENST00000409187ENST00000536059CCDC148chr2

159312927

-ACTR3chr2

114684922

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000283233CCDC148chr2159312927-ENST00000263238ACTR3chr2114684922+65123393091370353
ENST00000283233CCDC148chr2159312927-ENST00000536059ACTR3chr2114684922+14863393091370353
ENST00000283233CCDC148chr2159312927-ENST00000535589ACTR3chr2114684922+15073393091370353
ENST00000409889CCDC148chr2159312927-ENST00000263238ACTR3chr2114684922+64612882581319353
ENST00000409889CCDC148chr2159312927-ENST00000536059ACTR3chr2114684922+14352882581319353
ENST00000409889CCDC148chr2159312927-ENST00000535589ACTR3chr2114684922+14562882581319353

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000283233ENST00000263238CCDC148chr2159312927-ACTR3chr2114684922+8.61E-050.99991393
ENST00000283233ENST00000536059CCDC148chr2159312927-ACTR3chr2114684922+0.0003432790.9996567
ENST00000283233ENST00000535589CCDC148chr2159312927-ACTR3chr2114684922+0.0003236720.99967635
ENST00000409889ENST00000263238CCDC148chr2159312927-ACTR3chr2114684922+8.71E-050.999913
ENST00000409889ENST00000536059CCDC148chr2159312927-ACTR3chr2114684922+0.0003745360.99962544
ENST00000409889ENST00000535589CCDC148chr2159312927-ACTR3chr2114684922+0.000370150.99962986

Top

Fusion Genomic Features for CCDC148-ACTR3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CCDC148chr2159312926-ACTR3chr2114684921+4.20E-050.99995804
CCDC148chr2159312926-ACTR3chr2114684921+4.20E-050.99995804

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for CCDC148-ACTR3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:159312927/chr2:114684922)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ACTR3

Q9C0K3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells. {ECO:0000269|PubMed:11162478}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC148chr2:159312927chr2:114684922ENST00000283233-114166_1958592.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000283233-114352_4178592.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000283233-114466_4988592.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000409889-17166_1958256.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000409889-17352_4178256.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000409889-17466_4988256.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000536771-18166_1950300.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000536771-18352_4170300.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000536771-18466_4980300.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC148chr2:159312927chr2:114684922ENST00000283233-114395_4288592.0Compositional biasNote=Glu/Lys-rich
HgeneCCDC148chr2:159312927chr2:114684922ENST00000409889-17395_4288256.0Compositional biasNote=Glu/Lys-rich
HgeneCCDC148chr2:159312927chr2:114684922ENST00000536771-18395_4280300.0Compositional biasNote=Glu/Lys-rich


Top

Fusion Gene Sequence for CCDC148-ACTR3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13662_13662_1_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000263238_length(transcript)=6512nt_BP=339nt
ATAGAGACCGATGCTGTTCAGCGCGAGAGGGCCTGGAGAGGGTGGGTGTGAGAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTG
GCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGGCTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTA
GGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACCCCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTC
CTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTGCAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATA
GTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAATATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTG
ACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATAATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCT
GTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGAT
GGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATAT
TTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGT
TATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATC
TCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTT
ACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCT
GGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAA
TTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCA
ATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCA
GTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTC
TGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACACCAAACATGATTATACAGGAATATTTTAATAAGTGTATCACCAT
GCAGATGTAGAAGAGAGCGAAAGTGATTGTGTTTTTCTTTAGATTGAATATTTGAATCTTATGTGTAACAAAAAGAAGTGGGTTTTAGTT
CTTTCTGTGCCCTGATATTTTGTATATTAATGAATTATCCAAGATTCGATGGGATTTATCAGTGTGTAGATAGCTCTATAATGCTTGAAT
TGTACACTTCTAAGTGTGCAGTGCAAGAGCTTGTTTATATTTCATACTTTTTATACTTTGAGGAAAAAAAGTCAAAGAAAAATTGTATTT
GAGGGAAAAAACCATGACCAAGTAAAGGATAAATTCAAAAAATAGCCTCATGAGACTTGGCATACACACTCGTGGGATTCCAGTTATTAT
GGAGTGCTTCCATCCCTCTCCACCCCTTCCCCCCAAAAGGTTTTCTTTGCAAGTGCTTTTGGAACTAAGAGCTAGTATCTTGGATTAACT
GATGCCTGCTAGTGCTTTCTGATTACTCGCATTCTGTTTCTTGCTTTAAAAGAAGAGTAAAGACAAGAGTGTTGGACCAGTATTGCAGTT
CTGTAGTGTCATTTCTTATAAAAAACAAAACAACAACAATAATTTATCAAAATTGGCATATTTAAAGCCTAACATTCTAATAAAGGCACA
AATTTCTTTTTAATACTTGTTTCAGCCTCTTTAATCTCTTTATAAGTTAACTAATAAATCTATTTTCTTCAGACTTCTGCAATAGTTCTT
TAAAATCACAACAGTTAGCAAGCTGACTTTTGTAATGTGCTCAATACAAATACTTGTGAACTTTTAATATGTTGAGTGCTTTCATTTTGA
TAACTGGATCTCCATTTGATATTTTCATTTGTATAACTCATTTGCAGTCTGAAAATTTTTTTTAGTGCCAGTCCCTGAACATATCATTGA
AAGTTAATTTTCTTTGCATTTTAAAATATCTGGATTATGAAGAAAAAGTGATGAAAATAAATTAAAACTGAATTACCTTTTCTAATGTTT
TTTTTTTTTAAGTAATGTAATTCTATTTTGTTTTTATGTATGTGATATCTGTTTCTGTTGAGATTTGGGAGTTATTGAAATCTCTGTAAT
GTGTATGGTAGAAAATTTCTTGTGACCTTAAAATTTTACCAGTTATTTATAGAAAGAGAAAATGGGAAATGTTTTATAGGCTTTTTACTA
GCAGTATCAGTGAACACTTGAACTCCATTATTCATGAAAATAACACGTTAGGATTGGAATACGTCTATTCAAAAGTGAAAGAATATAAAG
TGTTTAGTTTTTTGTTTTTACTCTAAAGATAGAATTGGGGAGTAAACTTCAGTTTTTGTTTAGAGTGGATCTGAATATTTAAAATCCTAT
AATAATTTTTGTGAATCTTCATTCTTTGAGTATGGGATTGTAAAAGACAAACTATATCCTACAGTAGTATCATCATCAGTATCAAAGGTC
TCCTTTTTTTACTTGGAAAAGTAATTCACAAACATTATAAAAATACTATTCAAACAGTACCAAAGAGTAGATTAGCAAAAGTAAGTTTTT
TTCCCTAGCCTGTCTCATTTTTCCATCATTACACAGACTACTTGGAATGTCTTAGATGTCCTTGTATTGTAATTTTCTGTGTAGGTAGAA
ATAAATGTAGCTTTCTTATTTTACACAAATAGGAACTTACTGTATATACTGTTCTGCACTTTGCTTTTATTAAAGATCTTTTGATAAAGA
ACTATATTGATAAGCAGTAAAGATGTCATGCTCCTGGCCCAATAAAATATTGTTAGCATTGTCATAAATATGTCTTTTCCACCGGCGATG
GTTGGGTAGTTAAGTGAATAAGCTAGAAAGACATGTTTATAAAGCTATTTGATGACAATCTCAGGCATATTTATACAGAGATGTTCTTAA
CTGTTTGCTACAAAAACATGAAGATCAAAAACTTTCTTGAAGCTTACGCTTAACTTATTTGGGGAAACAAAACTCCAGCCCTTCTTGTGT
ATGTTCTGATATCCCTTTGCTCTACTTTTAGAGGAGTGAACCCTAATAGGATGGTAGCAGCATTCTTGTTTCTTTATATCTCTCCTCTGT
GATTGTATACCGTTTTTTCAACTTAAAGCAACTTCAGCTGGAAATATGTAGAGGTTGGCCAAGGTGAACTAAATAGTCTGTAACATTGAT
TAGATATCAAGCAACGTGAGCATGGTAGCAAAAGCACTAACTGAAGCCAGTGATTTAATTTTTAATTCTGATTCTGATAATTGATGATAT
AGCTCCTCGAACTTTGTTTTTTGTTAAAACTTGGAAAATATATTTGTATTATTTTGGACAAATTATTTGAACTCTCTGGACCTTGATTCA
ATTTATATATAAGGTAAAGGCATTATACTGGATTATCCTGCAATTTCTTTGAGTTGTTAGAATATAATGTAGCTTATTAATAGCAATATT
AGCAGTGTAGTAGATTCTGACTGCAAAACCTAGCCTTTTCTATTGATTCATTAGTGGTAGTAAAGGTATTATCTGATTTATCCTTTTTAA
TAGGCAGTGCTTTGATCAAGTGGGAAATAGTAATGGACAAATAAAATCAATGATCATTATCTAACTTGATGCCTGCTTTTCAAAAAGTGA
GCAAATTTCACATCTTCACCCTTAGACATTAATTCATGGCACCTACTATAAGTACTCATCCTCTTCTTACCTATCTTCTTTTCTATAGGA
GATAAAGTGGTTATTCAGACCCCCCAATACAATTTTTTGGTTTGTTTTCACAGCTACTTAAAAGATTAAAATAACTATTCTTGCAGATAT
TTCTAGGAATATTTTTAGAAATAATATGAAATACAGGGATAATAGGCCAATTATGATCTTTATTTTTAATTTCTACAGAAAAGTACTAGA
GAATATATCTATAGAAACTTCTTTCAGATAACCCTAAAGATGATACTAGAATGTTTATAAAATTATTGAGAAGATTATTTGTGTTATAAA
GCTTATTTGTACCATAGTAAAGGATGTTTTTGTTCCTCTTCATTCTGGGCTAATCTGTCAATACTGAAGTCCAGTCTTTTCCCCCTTTTC
TTACCAGCTCAACCTTGATTCCTGTGACCCATTCTTTCTGATCTTTCGTAGTTCATAGTCACCAGGCATGAGTACCTTGGATAGCCCTCT
GAAGTCTGTTACCACCCAGATTTCCAACTCGGGTTAATTGGTACTAATTCTATTAGCTGGTATAAATAATCCAAAATCTGTGCAGACTCT
GGGAGCAAAATGTTCTACTCAGTTTGGAATACTGTGCCTTAAAATATATTTCATTGTAACAGCACCTTGTATATATAGTTGGCCAAGGAC
AGAGTTGTTACAAGTTACGTGGAACTTTCATAGCAAATCTTGACAGTAAATACCTTGTTCTTGTATTAGGTCTATATCCTGAATTGACCT
TTAGCAAGAATCTTTAGATCTGCTGGAGGGCTGGGATGGCTTTTGGACTTCAGTGAAAAAGAATTTCTGCTACTCATTGTTGATAACGCT
TCAGTACTGTATAAATGTTTATCCTTTTCCACGTAATTTGTTTTCTATGATATGAGAACTTTTATTATAATTTGCCTCAGTCTTGATAGA
ATCTTAACAAAAATAAAATCTGTGGTCGTCTGAGGTATTCTCCATGCTATAACCCAGTTTAGCTGATGCATTTGGAGCTTGGGTGCTGAA
ATTAAATATAACCTATTTGAGTTAAGGATTTATTACTAGTGCTCCAGTGGTCACAGGAACAATAAAAAAGGAACAACGATAGAAATACGT
GATCTAGGAAAGAAGGCAACTGAAAAACCTGAAAGAAAAAAAATGAAAGATTAAAAGTATACGATATTCTATTTTGATTTAGCAATTACT
TGTTTTCTAGTGTTCTGTCAATTTTTGGTGACTTTTATAATTACATTAAAACTAAGATGCTGAATTAAAATAAAGTTTCTCTTTTATTCA
AGCACCAACATTCACTTATATTACCTATATATTGCATCAAGTTTTGAGCCTTCAATCCCAGAAGCATTGATTGACTGTCTACTGTGGTTC
AAGTACTGTGCATAAAGATGAATAAATATTCTGTCCTTGGCTTAGTCTAATAGTAAAGGCACTCTTAGAGGAGGGACAAATATTTTGCCT
AGATAAGATTTGAGAGATAGTAAGTGCGGAATTTCTCTTCATAAAAATGGTAGTGTTAGTTGTTTAGAGGGAGAAGTCCAGCTATGTAAG
GTGAAAGTGGGGCTTATAAAAGTGGATCTATTGTTTAAAAATTAGTACTTTGCTCCTAAAATTTTTACCTAAGTGTTACATCCAACAACA
GATGAAAGTAATTCGACAGTAGCATCTGCTTTATTCATTTCATATTTCCAGTGCCTGACATATTGCTTGGCATATAGTAGTTTAGTGGAT
GTGTTTGATGAATGAATGAGTAAAAATTATTTTTCATGTTAAAATAAAACTTTGAATTACATGAGTATACAACTTTTGTTCCTTCAAAAT
ACCCATATTTGTCAAATATGACCGAATTACGACTTTTTTTCTGTTCCACTAGTTTCTACCTTAGAAGTGACATTCTGCGTAAGGTAGTGG
GGGATTACTAAGTGATCATGACTTTTCTGAAGCAGGTCTTAAATAATTATCTAAGCCTTCAGTCATTTCAAAATCTCTGTAGTGTAAATG
ATCACAGGCTCTAAATCAGATTGTTGTACAAGGTAATTGACATGTCCTGAAATGTAACATTCAACATTAACAGTAGAAACAGGCCTCATT
TCTCCCTCTGGCTTTTATTGATCAATTTTGATATTGTCCAGATCCCATGTTAAACCACTTGATTTAGAGATGACTTAATTCTAAACTTCC
TCCATTTTTAATTAATAAGATTCAAGGTTGCAGTAAATTGTTAATCTTATTTGGAATTATATTAGAAAGTCGATATCGGAATTGGAACCA

>13662_13662_1_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000263238_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------
>13662_13662_2_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000535589_length(transcript)=1507nt_BP=339nt
ATAGAGACCGATGCTGTTCAGCGCGAGAGGGCCTGGAGAGGGTGGGTGTGAGAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTG
GCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGGCTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTA
GGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACCCCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTC
CTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTGCAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATA
GTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAATATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTG
ACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATAATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCT
GTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGAT
GGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATAT
TTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGT
TATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATC
TCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTT
ACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCT
GGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAA
TTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCA
ATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCA
GTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTC

>13662_13662_2_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000535589_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------
>13662_13662_3_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000536059_length(transcript)=1486nt_BP=339nt
ATAGAGACCGATGCTGTTCAGCGCGAGAGGGCCTGGAGAGGGTGGGTGTGAGAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTG
GCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGGCTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTA
GGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACCCCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTC
CTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTGCAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATA
GTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAATATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTG
ACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATAATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCT
GTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGAT
GGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATAT
TTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGT
TATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATC
TCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTT
ACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCT
GGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAA
TTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCA
ATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCA
GTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTC

>13662_13662_3_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000283233_ACTR3_chr2_114684922_ENST00000536059_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------
>13662_13662_4_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000263238_length(transcript)=6461nt_BP=288nt
GAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTGGCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGG
CTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTAGGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACC
CCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTCCTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTG
CAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATAGTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAA
TATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTGACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATA
ATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCTGTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGA
GAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGT
ATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAA
TCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGG
TCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCT
GAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATT
GATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTG
AAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACA
CACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGAT
TATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGA
GGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTCTGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACACCAAA
CATGATTATACAGGAATATTTTAATAAGTGTATCACCATGCAGATGTAGAAGAGAGCGAAAGTGATTGTGTTTTTCTTTAGATTGAATAT
TTGAATCTTATGTGTAACAAAAAGAAGTGGGTTTTAGTTCTTTCTGTGCCCTGATATTTTGTATATTAATGAATTATCCAAGATTCGATG
GGATTTATCAGTGTGTAGATAGCTCTATAATGCTTGAATTGTACACTTCTAAGTGTGCAGTGCAAGAGCTTGTTTATATTTCATACTTTT
TATACTTTGAGGAAAAAAAGTCAAAGAAAAATTGTATTTGAGGGAAAAAACCATGACCAAGTAAAGGATAAATTCAAAAAATAGCCTCAT
GAGACTTGGCATACACACTCGTGGGATTCCAGTTATTATGGAGTGCTTCCATCCCTCTCCACCCCTTCCCCCCAAAAGGTTTTCTTTGCA
AGTGCTTTTGGAACTAAGAGCTAGTATCTTGGATTAACTGATGCCTGCTAGTGCTTTCTGATTACTCGCATTCTGTTTCTTGCTTTAAAA
GAAGAGTAAAGACAAGAGTGTTGGACCAGTATTGCAGTTCTGTAGTGTCATTTCTTATAAAAAACAAAACAACAACAATAATTTATCAAA
ATTGGCATATTTAAAGCCTAACATTCTAATAAAGGCACAAATTTCTTTTTAATACTTGTTTCAGCCTCTTTAATCTCTTTATAAGTTAAC
TAATAAATCTATTTTCTTCAGACTTCTGCAATAGTTCTTTAAAATCACAACAGTTAGCAAGCTGACTTTTGTAATGTGCTCAATACAAAT
ACTTGTGAACTTTTAATATGTTGAGTGCTTTCATTTTGATAACTGGATCTCCATTTGATATTTTCATTTGTATAACTCATTTGCAGTCTG
AAAATTTTTTTTAGTGCCAGTCCCTGAACATATCATTGAAAGTTAATTTTCTTTGCATTTTAAAATATCTGGATTATGAAGAAAAAGTGA
TGAAAATAAATTAAAACTGAATTACCTTTTCTAATGTTTTTTTTTTTTAAGTAATGTAATTCTATTTTGTTTTTATGTATGTGATATCTG
TTTCTGTTGAGATTTGGGAGTTATTGAAATCTCTGTAATGTGTATGGTAGAAAATTTCTTGTGACCTTAAAATTTTACCAGTTATTTATA
GAAAGAGAAAATGGGAAATGTTTTATAGGCTTTTTACTAGCAGTATCAGTGAACACTTGAACTCCATTATTCATGAAAATAACACGTTAG
GATTGGAATACGTCTATTCAAAAGTGAAAGAATATAAAGTGTTTAGTTTTTTGTTTTTACTCTAAAGATAGAATTGGGGAGTAAACTTCA
GTTTTTGTTTAGAGTGGATCTGAATATTTAAAATCCTATAATAATTTTTGTGAATCTTCATTCTTTGAGTATGGGATTGTAAAAGACAAA
CTATATCCTACAGTAGTATCATCATCAGTATCAAAGGTCTCCTTTTTTTACTTGGAAAAGTAATTCACAAACATTATAAAAATACTATTC
AAACAGTACCAAAGAGTAGATTAGCAAAAGTAAGTTTTTTTCCCTAGCCTGTCTCATTTTTCCATCATTACACAGACTACTTGGAATGTC
TTAGATGTCCTTGTATTGTAATTTTCTGTGTAGGTAGAAATAAATGTAGCTTTCTTATTTTACACAAATAGGAACTTACTGTATATACTG
TTCTGCACTTTGCTTTTATTAAAGATCTTTTGATAAAGAACTATATTGATAAGCAGTAAAGATGTCATGCTCCTGGCCCAATAAAATATT
GTTAGCATTGTCATAAATATGTCTTTTCCACCGGCGATGGTTGGGTAGTTAAGTGAATAAGCTAGAAAGACATGTTTATAAAGCTATTTG
ATGACAATCTCAGGCATATTTATACAGAGATGTTCTTAACTGTTTGCTACAAAAACATGAAGATCAAAAACTTTCTTGAAGCTTACGCTT
AACTTATTTGGGGAAACAAAACTCCAGCCCTTCTTGTGTATGTTCTGATATCCCTTTGCTCTACTTTTAGAGGAGTGAACCCTAATAGGA
TGGTAGCAGCATTCTTGTTTCTTTATATCTCTCCTCTGTGATTGTATACCGTTTTTTCAACTTAAAGCAACTTCAGCTGGAAATATGTAG
AGGTTGGCCAAGGTGAACTAAATAGTCTGTAACATTGATTAGATATCAAGCAACGTGAGCATGGTAGCAAAAGCACTAACTGAAGCCAGT
GATTTAATTTTTAATTCTGATTCTGATAATTGATGATATAGCTCCTCGAACTTTGTTTTTTGTTAAAACTTGGAAAATATATTTGTATTA
TTTTGGACAAATTATTTGAACTCTCTGGACCTTGATTCAATTTATATATAAGGTAAAGGCATTATACTGGATTATCCTGCAATTTCTTTG
AGTTGTTAGAATATAATGTAGCTTATTAATAGCAATATTAGCAGTGTAGTAGATTCTGACTGCAAAACCTAGCCTTTTCTATTGATTCAT
TAGTGGTAGTAAAGGTATTATCTGATTTATCCTTTTTAATAGGCAGTGCTTTGATCAAGTGGGAAATAGTAATGGACAAATAAAATCAAT
GATCATTATCTAACTTGATGCCTGCTTTTCAAAAAGTGAGCAAATTTCACATCTTCACCCTTAGACATTAATTCATGGCACCTACTATAA
GTACTCATCCTCTTCTTACCTATCTTCTTTTCTATAGGAGATAAAGTGGTTATTCAGACCCCCCAATACAATTTTTTGGTTTGTTTTCAC
AGCTACTTAAAAGATTAAAATAACTATTCTTGCAGATATTTCTAGGAATATTTTTAGAAATAATATGAAATACAGGGATAATAGGCCAAT
TATGATCTTTATTTTTAATTTCTACAGAAAAGTACTAGAGAATATATCTATAGAAACTTCTTTCAGATAACCCTAAAGATGATACTAGAA
TGTTTATAAAATTATTGAGAAGATTATTTGTGTTATAAAGCTTATTTGTACCATAGTAAAGGATGTTTTTGTTCCTCTTCATTCTGGGCT
AATCTGTCAATACTGAAGTCCAGTCTTTTCCCCCTTTTCTTACCAGCTCAACCTTGATTCCTGTGACCCATTCTTTCTGATCTTTCGTAG
TTCATAGTCACCAGGCATGAGTACCTTGGATAGCCCTCTGAAGTCTGTTACCACCCAGATTTCCAACTCGGGTTAATTGGTACTAATTCT
ATTAGCTGGTATAAATAATCCAAAATCTGTGCAGACTCTGGGAGCAAAATGTTCTACTCAGTTTGGAATACTGTGCCTTAAAATATATTT
CATTGTAACAGCACCTTGTATATATAGTTGGCCAAGGACAGAGTTGTTACAAGTTACGTGGAACTTTCATAGCAAATCTTGACAGTAAAT
ACCTTGTTCTTGTATTAGGTCTATATCCTGAATTGACCTTTAGCAAGAATCTTTAGATCTGCTGGAGGGCTGGGATGGCTTTTGGACTTC
AGTGAAAAAGAATTTCTGCTACTCATTGTTGATAACGCTTCAGTACTGTATAAATGTTTATCCTTTTCCACGTAATTTGTTTTCTATGAT
ATGAGAACTTTTATTATAATTTGCCTCAGTCTTGATAGAATCTTAACAAAAATAAAATCTGTGGTCGTCTGAGGTATTCTCCATGCTATA
ACCCAGTTTAGCTGATGCATTTGGAGCTTGGGTGCTGAAATTAAATATAACCTATTTGAGTTAAGGATTTATTACTAGTGCTCCAGTGGT
CACAGGAACAATAAAAAAGGAACAACGATAGAAATACGTGATCTAGGAAAGAAGGCAACTGAAAAACCTGAAAGAAAAAAAATGAAAGAT
TAAAAGTATACGATATTCTATTTTGATTTAGCAATTACTTGTTTTCTAGTGTTCTGTCAATTTTTGGTGACTTTTATAATTACATTAAAA
CTAAGATGCTGAATTAAAATAAAGTTTCTCTTTTATTCAAGCACCAACATTCACTTATATTACCTATATATTGCATCAAGTTTTGAGCCT
TCAATCCCAGAAGCATTGATTGACTGTCTACTGTGGTTCAAGTACTGTGCATAAAGATGAATAAATATTCTGTCCTTGGCTTAGTCTAAT
AGTAAAGGCACTCTTAGAGGAGGGACAAATATTTTGCCTAGATAAGATTTGAGAGATAGTAAGTGCGGAATTTCTCTTCATAAAAATGGT
AGTGTTAGTTGTTTAGAGGGAGAAGTCCAGCTATGTAAGGTGAAAGTGGGGCTTATAAAAGTGGATCTATTGTTTAAAAATTAGTACTTT
GCTCCTAAAATTTTTACCTAAGTGTTACATCCAACAACAGATGAAAGTAATTCGACAGTAGCATCTGCTTTATTCATTTCATATTTCCAG
TGCCTGACATATTGCTTGGCATATAGTAGTTTAGTGGATGTGTTTGATGAATGAATGAGTAAAAATTATTTTTCATGTTAAAATAAAACT
TTGAATTACATGAGTATACAACTTTTGTTCCTTCAAAATACCCATATTTGTCAAATATGACCGAATTACGACTTTTTTTCTGTTCCACTA
GTTTCTACCTTAGAAGTGACATTCTGCGTAAGGTAGTGGGGGATTACTAAGTGATCATGACTTTTCTGAAGCAGGTCTTAAATAATTATC
TAAGCCTTCAGTCATTTCAAAATCTCTGTAGTGTAAATGATCACAGGCTCTAAATCAGATTGTTGTACAAGGTAATTGACATGTCCTGAA
ATGTAACATTCAACATTAACAGTAGAAACAGGCCTCATTTCTCCCTCTGGCTTTTATTGATCAATTTTGATATTGTCCAGATCCCATGTT
AAACCACTTGATTTAGAGATGACTTAATTCTAAACTTCCTCCATTTTTAATTAATAAGATTCAAGGTTGCAGTAAATTGTTAATCTTATT

>13662_13662_4_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000263238_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------
>13662_13662_5_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000535589_length(transcript)=1456nt_BP=288nt
GAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTGGCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGG
CTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTAGGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACC
CCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTCCTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTG
CAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATAGTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAA
TATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTGACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATA
ATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCTGTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGA
GAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGT
ATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAA
TCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGG
TCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCT
GAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATT
GATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTG
AAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACA
CACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGAT
TATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGA
GGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTCTGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACACCAAA

>13662_13662_5_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000535589_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------
>13662_13662_6_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000536059_length(transcript)=1435nt_BP=288nt
GAGAGAAGGTGTCTCAGGTCTCGGGCGCGGGAGGGGGTGGCGGAGAGGACAGGGAGATTCCCCAGCGCTGGCTCTGAAATCTGGGGCAGG
CTTTCCTTGCCTTACTGCCAATCCCAACTGTGCCTGGTAGGGTTTGTCCCTGGCGTCAAAGGTAGGAACAGCTGAGCCCTTAGATGTACC
CCTGACGGCGAGAGCCCAGGAGTGGGCGTTTCACTTTTCCTGCGTTTGGGGAGTCCCTGAGGCTATGCCCTTTGACCTTTGACATGTGTG
CAGCTTCTGCTTCTCCAGTGGCCAATCCGCCATGGTATAGTTGAAGATTGGGACTTAATGGAAAGGTTTATGGAGCAAGTGATCTTTAAA
TATTTAAGGGCAGAACCTGAAGACCATTATTTTCTTTTGACTGAACCTCCATTGAATACTCCAGAAAACAGGGAATATACTGCTGAAATA
ATGTTTGAGTCCTTCAATGTTCCAGGCTTGTACATTGCTGTGCAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGA
GAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGT
ATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAA
TCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGG
TCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCT
GAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATT
GATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTG
AAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACA
CACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGAT
TATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGA

>13662_13662_6_CCDC148-ACTR3_CCDC148_chr2_159312927_ENST00000409889_ACTR3_chr2_114684922_ENST00000536059_length(amino acids)=353AA_BP=10
MTCVQLLLLQWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTS
RQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKY
DTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CCDC148-ACTR3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CCDC148-ACTR3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CCDC148-ACTR3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource