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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCDC90B-CLPB (FusionGDB2 ID:13983)

Fusion Gene Summary for CCDC90B-CLPB

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC90B-CLPB
Fusion gene ID: 13983
HgeneTgene
Gene symbol

CCDC90B

CLPB

Gene ID

60492

81570

Gene namecoiled-coil domain containing 90Bcaseinolytic mitochondrial matrix peptidase chaperone subunit B
SynonymsMDS011|MDS025ANKCLB|HSP78|MEGCANN|MGCA7|SKD3
Cytomap

11q14.1

11q13.4

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 90B, mitochondrialcaseinolytic peptidase B protein homologClpB caseinolytic peptidase B homologClpB homolog, mitochondrial AAA ATPase chaperoninankyrin-repeat containing bacterial clp fusionsuppressor of potassium transport defect 3testicular secretory protein Li 11
Modification date2020031520200313
UniProtAcc

Q9GZT6

Q9H078

Ensembl transtripts involved in fusion geneENST00000529073, ENST00000529689, 
ENST00000529611, ENST00000455220, 
ENST00000525503, ENST00000525504, 
ENST00000445069, ENST00000538021, 
ENST00000542555, ENST00000294053, 
ENST00000340729, ENST00000437826, 
ENST00000538039, ENST00000543042, 
Fusion gene scores* DoF score5 X 6 X 4=12012 X 11 X 8=1056
# samples 615
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1056*10)=-2.81557542886257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCDC90B [Title/Abstract] AND CLPB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC90B(82996916)-CLPB(72013392), # samples:1
CCDC90B(82996170)-CLPB(72013392), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCLPB

GO:0034605

cellular response to heat

2745427


check buttonFusion gene breakpoints across CCDC90B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLPB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-95-7039-01ACCDC90Bchr11

82996170

-CLPBchr11

72013392

-
ChimerDB4LUADTCGA-95-7039-01ACCDC90Bchr11

82996916

-CLPBchr11

72013392

-


Top

Fusion Gene ORF analysis for CCDC90B-CLPB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000529073ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5CDS-intronENST00000529073ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5CDS-intronENST00000529073ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5CDS-intronENST00000529689ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5CDS-intronENST00000529689ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5CDS-intronENST00000529689ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
5UTR-3CDSENST00000529611ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-3CDSENST00000529611ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-3CDSENST00000529611ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-3CDSENST00000529611ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-3CDSENST00000529611ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-intronENST00000529611ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-intronENST00000529611ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
5UTR-intronENST00000529611ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
In-frameENST00000529073ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529073ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529073ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529073ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529073ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529689ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529689ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529689ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529689ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
In-frameENST00000529689ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000455220ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525503ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000525504ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529073ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529073ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529073ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529073ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529073ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529611ENST00000294053CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529611ENST00000340729CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529611ENST00000437826CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529611ENST00000538039CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529611ENST00000543042CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-3CDSENST00000529689ENST00000294053CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529689ENST00000340729CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529689ENST00000437826CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529689ENST00000538039CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-3CDSENST00000529689ENST00000543042CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000455220ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525503ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000525504ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000529073ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000529073ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000529073ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000529611ENST00000445069CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000529611ENST00000538021CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000529611ENST00000542555CCDC90Bchr11

82996916

-CLPBchr11

72013392

-
intron-intronENST00000529689ENST00000445069CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000529689ENST00000538021CCDC90Bchr11

82996170

-CLPBchr11

72013392

-
intron-intronENST00000529689ENST00000542555CCDC90Bchr11

82996170

-CLPBchr11

72013392

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000529689CCDC90Bchr1182996916-ENST00000294053CLPBchr1172013392-23895355471446299
ENST00000529689CCDC90Bchr1182996916-ENST00000538039CLPBchr1172013392-23685355471446299
ENST00000529689CCDC90Bchr1182996916-ENST00000437826CLPBchr1172013392-15115355471446299
ENST00000529689CCDC90Bchr1182996916-ENST00000340729CLPBchr1172013392-15115355471446299
ENST00000529689CCDC90Bchr1182996916-ENST00000543042CLPBchr1172013392-15055355471446299
ENST00000529073CCDC90Bchr1182996916-ENST00000294053CLPBchr1172013392-19601061181017299
ENST00000529073CCDC90Bchr1182996916-ENST00000538039CLPBchr1172013392-19391061181017299
ENST00000529073CCDC90Bchr1182996916-ENST00000437826CLPBchr1172013392-10821061181017299
ENST00000529073CCDC90Bchr1182996916-ENST00000340729CLPBchr1172013392-10821061181017299
ENST00000529073CCDC90Bchr1182996916-ENST00000543042CLPBchr1172013392-10761061181017299

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000529689ENST00000294053CCDC90Bchr1182996916-CLPBchr1172013392-0.0069049690.993095
ENST00000529689ENST00000538039CCDC90Bchr1182996916-CLPBchr1172013392-0.0073542740.99264574
ENST00000529689ENST00000437826CCDC90Bchr1182996916-CLPBchr1172013392-0.0056786330.99432135
ENST00000529689ENST00000340729CCDC90Bchr1182996916-CLPBchr1172013392-0.0056786330.99432135
ENST00000529689ENST00000543042CCDC90Bchr1182996916-CLPBchr1172013392-0.0061340820.9938659
ENST00000529073ENST00000294053CCDC90Bchr1182996916-CLPBchr1172013392-0.0032949970.996705
ENST00000529073ENST00000538039CCDC90Bchr1182996916-CLPBchr1172013392-0.0035678670.99643207
ENST00000529073ENST00000437826CCDC90Bchr1182996916-CLPBchr1172013392-0.0010071710.99899286
ENST00000529073ENST00000340729CCDC90Bchr1182996916-CLPBchr1172013392-0.0010071710.99899286
ENST00000529073ENST00000543042CCDC90Bchr1182996916-CLPBchr1172013392-0.0011657840.9988342

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Fusion Genomic Features for CCDC90B-CLPB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CCDC90B-CLPB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:82996916/chr11:72013392)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CCDC90B

Q9GZT6

CLPB

Q9H078

FUNCTION: May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and proinflammatory cytokine IL6 (PubMed:31522117). {ECO:0000269|PubMed:31522117}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCLPBchr11:82996916chr11:72013392ENST00000340729715381_388345649.0Nucleotide bindingATP
TgeneCLPBchr11:82996916chr11:72013392ENST000004378261018381_388359663.0Nucleotide bindingATP
TgeneCLPBchr11:82996916chr11:72013392ENST00000538039816381_388374678.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC90Bchr11:82996916chr11:72013392ENST00000455220-19129_1640246.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC90Bchr11:82996916chr11:72013392ENST00000529689-19129_16433255.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC90Bchr11:82996916chr11:72013392ENST00000455220-19231_2530246.0TransmembraneHelical
HgeneCCDC90Bchr11:82996916chr11:72013392ENST00000529689-19231_25333255.0TransmembraneHelical
TgeneCLPBchr11:82996916chr11:72013392ENST00000294053917381_388404708.0Nucleotide bindingATP
TgeneCLPBchr11:82996916chr11:72013392ENST00000294053917133_162404708.0RepeatNote=ANK 1
TgeneCLPBchr11:82996916chr11:72013392ENST00000294053917166_195404708.0RepeatNote=ANK 2
TgeneCLPBchr11:82996916chr11:72013392ENST00000294053917265_295404708.0RepeatNote=ANK 3
TgeneCLPBchr11:82996916chr11:72013392ENST00000294053917298_327404708.0RepeatNote=ANK 4
TgeneCLPBchr11:82996916chr11:72013392ENST00000340729715133_162345649.0RepeatNote=ANK 1
TgeneCLPBchr11:82996916chr11:72013392ENST00000340729715166_195345649.0RepeatNote=ANK 2
TgeneCLPBchr11:82996916chr11:72013392ENST00000340729715265_295345649.0RepeatNote=ANK 3
TgeneCLPBchr11:82996916chr11:72013392ENST00000340729715298_327345649.0RepeatNote=ANK 4
TgeneCLPBchr11:82996916chr11:72013392ENST000004378261018133_162359663.0RepeatNote=ANK 1
TgeneCLPBchr11:82996916chr11:72013392ENST000004378261018166_195359663.0RepeatNote=ANK 2
TgeneCLPBchr11:82996916chr11:72013392ENST000004378261018265_295359663.0RepeatNote=ANK 3
TgeneCLPBchr11:82996916chr11:72013392ENST000004378261018298_327359663.0RepeatNote=ANK 4
TgeneCLPBchr11:82996916chr11:72013392ENST00000538039816133_162374678.0RepeatNote=ANK 1
TgeneCLPBchr11:82996916chr11:72013392ENST00000538039816166_195374678.0RepeatNote=ANK 2
TgeneCLPBchr11:82996916chr11:72013392ENST00000538039816265_295374678.0RepeatNote=ANK 3
TgeneCLPBchr11:82996916chr11:72013392ENST00000538039816298_327374678.0RepeatNote=ANK 4


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Fusion Gene Sequence for CCDC90B-CLPB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13983_13983_1_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000294053_length(transcript)=1960nt_BP=106nt
GAGGACATGAATAGTCGCCAGGCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCG
CCGGCCCTGCGGAGAGGGCTTCATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGG
CTACGTTGGCCATGAGGAGGGTGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGC
CCATCCAGATGTGCTCACCATCATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGC
CATCTTCATCATGACCTCCAATGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAA
CCGTATTGCCGAAAACCTGGGGGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCT
GAAAGCTCACTTCCGGAGGGATGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACT
CGTCAACAAGGAACTAAACTTCTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCT
GGTCGACGGCTACAATGTGCACTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGA
GCAGGACCTGCTGCCAGGGGGCTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACC
CCAGGCTGAGAAGCGCCTCCCCAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCA
CCCTGAGAAGGTGTGCAACACCATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATG
GCAACTGACTTACCTTCCCCTCATGCCGCTCCCATCTCTACCCAGTCTCAGGCCTGCTTACCTCCTCACAGCCCATGAAGACCCCTTCTC
AGCCCCAAAACCTGAAGGAGGAATTTCGCCCTACTCTGGCCCCTTTGTTGTGGGCCCATAACCTGCTAACAAGCCTTCAGGAGAGGAGCT
GCCTTTCCACCCCCTTCAAGGCAAGGAGGGATGGAGGTCCCTTATTTCCTTCAGAATGATCCCCATCCCCCATAGTCGCCAGACTTTCTC
ATGTTCCCAGGAAGCTCAGAAGTATGGCAGCTAAGAACACAGCTGGCTGGAAGAAGACAGGGACCAGACTGAACTGCCACCCTCTGCTAG
TCCTCATGCAACTCAGTCCCCAGAATGGCTCCACTGGGAGTGGAGGAAGAGCTCAGAGGCCCAGGTGCAGATAGTTCTGCAATTTAGTCT
GTAGCCTCCTCGTTCCCTACCCTAAAATTCTAAGGGGAAGGGACCCATAGAGGCTTGCCTGTTTCCGCTACTATATTATGCCCAGTGTTC
CTCCTCACCCCACGTCCTGGGGTCAGGCCAGACCATGTTTCGTCAGCCTTGGGGACTAGGCCAGTGTTGGGCACCTCCAGGAGGAGGCCT
GACTGGTTCATTACCCTCCCCTACTCAGACTGAGCAGCAGTCCCAGATAACCAAGCAAGCTCAGCTCTGTGGGGGCCTCCTTCAAAAGAC
CAACATCGCAGACATTAGGAAGCTGTAGGAAGAGAGATCATGGGTTTGACCTCTGCCCACATGGCCATGGAGTCAGCCTCAGCCCTGTCT

>13983_13983_1_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000294053_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_2_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000340729_length(transcript)=1082nt_BP=106nt
GAGGACATGAATAGTCGCCAGGCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCG
CCGGCCCTGCGGAGAGGGCTTCATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGG
CTACGTTGGCCATGAGGAGGGTGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGC
CCATCCAGATGTGCTCACCATCATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGC
CATCTTCATCATGACCTCCAATGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAA
CCGTATTGCCGAAAACCTGGGGGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCT
GAAAGCTCACTTCCGGAGGGATGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACT
CGTCAACAAGGAACTAAACTTCTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCT
GGTCGACGGCTACAATGTGCACTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGA
GCAGGACCTGCTGCCAGGGGGCTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACC
CCAGGCTGAGAAGCGCCTCCCCAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCA
CCCTGAGAAGGTGTGCAACACCATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATG

>13983_13983_2_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000340729_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_3_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000437826_length(transcript)=1082nt_BP=106nt
GAGGACATGAATAGTCGCCAGGCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCG
CCGGCCCTGCGGAGAGGGCTTCATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGG
CTACGTTGGCCATGAGGAGGGTGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGC
CCATCCAGATGTGCTCACCATCATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGC
CATCTTCATCATGACCTCCAATGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAA
CCGTATTGCCGAAAACCTGGGGGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCT
GAAAGCTCACTTCCGGAGGGATGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACT
CGTCAACAAGGAACTAAACTTCTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCT
GGTCGACGGCTACAATGTGCACTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGA
GCAGGACCTGCTGCCAGGGGGCTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACC
CCAGGCTGAGAAGCGCCTCCCCAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCA
CCCTGAGAAGGTGTGCAACACCATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATG

>13983_13983_3_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000437826_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_4_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000538039_length(transcript)=1939nt_BP=106nt
GAGGACATGAATAGTCGCCAGGCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCG
CCGGCCCTGCGGAGAGGGCTTCATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGG
CTACGTTGGCCATGAGGAGGGTGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGC
CCATCCAGATGTGCTCACCATCATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGC
CATCTTCATCATGACCTCCAATGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAA
CCGTATTGCCGAAAACCTGGGGGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCT
GAAAGCTCACTTCCGGAGGGATGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACT
CGTCAACAAGGAACTAAACTTCTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCT
GGTCGACGGCTACAATGTGCACTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGA
GCAGGACCTGCTGCCAGGGGGCTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACC
CCAGGCTGAGAAGCGCCTCCCCAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCA
CCCTGAGAAGGTGTGCAACACCATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATG
GCAACTGACTTACCTTCCCCTCATGCCGCTCCCATCTCTACCCAGTCTCAGGCCTGCTTACCTCCTCACAGCCCATGAAGACCCCTTCTC
AGCCCCAAAACCTGAAGGAGGAATTTCGCCCTACTCTGGCCCCTTTGTTGTGGGCCCATAACCTGCTAACAAGCCTTCAGGAGAGGAGCT
GCCTTTCCACCCCCTTCAAGGCAAGGAGGGATGGAGGTCCCTTATTTCCTTCAGAATGATCCCCATCCCCCATAGTCGCCAGACTTTCTC
ATGTTCCCAGGAAGCTCAGAAGTATGGCAGCTAAGAACACAGCTGGCTGGAAGAAGACAGGGACCAGACTGAACTGCCACCCTCTGCTAG
TCCTCATGCAACTCAGTCCCCAGAATGGCTCCACTGGGAGTGGAGGAAGAGCTCAGAGGCCCAGGTGCAGATAGTTCTGCAATTTAGTCT
GTAGCCTCCTCGTTCCCTACCCTAAAATTCTAAGGGGAAGGGACCCATAGAGGCTTGCCTGTTTCCGCTACTATATTATGCCCAGTGTTC
CTCCTCACCCCACGTCCTGGGGTCAGGCCAGACCATGTTTCGTCAGCCTTGGGGACTAGGCCAGTGTTGGGCACCTCCAGGAGGAGGCCT
GACTGGTTCATTACCCTCCCCTACTCAGACTGAGCAGCAGTCCCAGATAACCAAGCAAGCTCAGCTCTGTGGGGGCCTCCTTCAAAAGAC
CAACATCGCAGACATTAGGAAGCTGTAGGAAGAGAGATCATGGGTTTGACCTCTGCCCACATGGCCATGGAGTCAGCCTCAGCCCTGTCT

>13983_13983_4_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000538039_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_5_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000543042_length(transcript)=1076nt_BP=106nt
GAGGACATGAATAGTCGCCAGGCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCG
CCGGCCCTGCGGAGAGGGCTTCATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGG
CTACGTTGGCCATGAGGAGGGTGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGC
CCATCCAGATGTGCTCACCATCATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGC
CATCTTCATCATGACCTCCAATGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAA
CCGTATTGCCGAAAACCTGGGGGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCT
GAAAGCTCACTTCCGGAGGGATGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACT
CGTCAACAAGGAACTAAACTTCTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCT
GGTCGACGGCTACAATGTGCACTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGA
GCAGGACCTGCTGCCAGGGGGCTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACC
CCAGGCTGAGAAGCGCCTCCCCAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCA

>13983_13983_5_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529073_CLPB_chr11_72013392_ENST00000543042_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_6_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000294053_length(transcript)=2389nt_BP=535nt
CAGCGGCCGAAAACTTCAGGTTCCAGGCTGCTGTGCGGCTAAATGCGACTCCATCTCCCCCGACCCAAGCGCGTAATGGCCGCTGGCTAT
CTTGGGGGAGCCAGCTGTTGGACTATGCCCCACTGCCAGGAAACAGGCGCCGGAAGGTTCTCTGACAAGATCTCGCTTTCCTAGGGCGGT
GAAGGCGTTCAAAGGTCGGGAAGGGGCGCTGGGAGAAGCGGGGCAGCGCTGAGCCATGCTCGCGAACTGTGGGTCTGTCTGTGAAGAGAC
CCAGTTTCGTGGGACCACGGTGGCGCCTGCGCTGGGAGGTGAGCTTGTGACAGAGCGAAAACTACAATTCCCAGCATTCCTGTGGTGCCA
GAACTACCTTGCCCGAAAGCCTGTGCGAGATTTACCCCGTCTTCCGCCTCCCTCCCACCGGAAAACTCTGAGGACATGAATAGTCGCCAG
GCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCGCCGGCCCTGCGGAGAGGGCTT
CATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGGCTACGTTGGCCATGAGGAGGG
TGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGCCCATCCAGATGTGCTCACCAT
CATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGCCATCTTCATCATGACCTCCAA
TGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAACCGTATTGCCGAAAACCTGGG
GGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCTGAAAGCTCACTTCCGGAGGGA
TGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACTCGTCAACAAGGAACTAAACTT
CTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCTGGTCGACGGCTACAATGTGCA
CTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGAGCAGGACCTGCTGCCAGGGGG
CTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACCCCAGGCTGAGAAGCGCCTCCC
CAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCACCCTGAGAAGGTGTGCAACAC
CATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATGGCAACTGACTTACCTTCCCCT
CATGCCGCTCCCATCTCTACCCAGTCTCAGGCCTGCTTACCTCCTCACAGCCCATGAAGACCCCTTCTCAGCCCCAAAACCTGAAGGAGG
AATTTCGCCCTACTCTGGCCCCTTTGTTGTGGGCCCATAACCTGCTAACAAGCCTTCAGGAGAGGAGCTGCCTTTCCACCCCCTTCAAGG
CAAGGAGGGATGGAGGTCCCTTATTTCCTTCAGAATGATCCCCATCCCCCATAGTCGCCAGACTTTCTCATGTTCCCAGGAAGCTCAGAA
GTATGGCAGCTAAGAACACAGCTGGCTGGAAGAAGACAGGGACCAGACTGAACTGCCACCCTCTGCTAGTCCTCATGCAACTCAGTCCCC
AGAATGGCTCCACTGGGAGTGGAGGAAGAGCTCAGAGGCCCAGGTGCAGATAGTTCTGCAATTTAGTCTGTAGCCTCCTCGTTCCCTACC
CTAAAATTCTAAGGGGAAGGGACCCATAGAGGCTTGCCTGTTTCCGCTACTATATTATGCCCAGTGTTCCTCCTCACCCCACGTCCTGGG
GTCAGGCCAGACCATGTTTCGTCAGCCTTGGGGACTAGGCCAGTGTTGGGCACCTCCAGGAGGAGGCCTGACTGGTTCATTACCCTCCCC
TACTCAGACTGAGCAGCAGTCCCAGATAACCAAGCAAGCTCAGCTCTGTGGGGGCCTCCTTCAAAAGACCAACATCGCAGACATTAGGAA
GCTGTAGGAAGAGAGATCATGGGTTTGACCTCTGCCCACATGGCCATGGAGTCAGCCTCAGCCCTGTCTGTACTGCTCGTCCAGCTAAAC

>13983_13983_6_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000294053_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_7_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000340729_length(transcript)=1511nt_BP=535nt
CAGCGGCCGAAAACTTCAGGTTCCAGGCTGCTGTGCGGCTAAATGCGACTCCATCTCCCCCGACCCAAGCGCGTAATGGCCGCTGGCTAT
CTTGGGGGAGCCAGCTGTTGGACTATGCCCCACTGCCAGGAAACAGGCGCCGGAAGGTTCTCTGACAAGATCTCGCTTTCCTAGGGCGGT
GAAGGCGTTCAAAGGTCGGGAAGGGGCGCTGGGAGAAGCGGGGCAGCGCTGAGCCATGCTCGCGAACTGTGGGTCTGTCTGTGAAGAGAC
CCAGTTTCGTGGGACCACGGTGGCGCCTGCGCTGGGAGGTGAGCTTGTGACAGAGCGAAAACTACAATTCCCAGCATTCCTGTGGTGCCA
GAACTACCTTGCCCGAAAGCCTGTGCGAGATTTACCCCGTCTTCCGCCTCCCTCCCACCGGAAAACTCTGAGGACATGAATAGTCGCCAG
GCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCGCCGGCCCTGCGGAGAGGGCTT
CATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGGCTACGTTGGCCATGAGGAGGG
TGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGCCCATCCAGATGTGCTCACCAT
CATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGCCATCTTCATCATGACCTCCAA
TGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAACCGTATTGCCGAAAACCTGGG
GGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCTGAAAGCTCACTTCCGGAGGGA
TGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACTCGTCAACAAGGAACTAAACTT
CTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCTGGTCGACGGCTACAATGTGCA
CTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGAGCAGGACCTGCTGCCAGGGGG
CTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACCCCAGGCTGAGAAGCGCCTCCC
CAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCACCCTGAGAAGGTGTGCAACAC

>13983_13983_7_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000340729_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_8_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000437826_length(transcript)=1511nt_BP=535nt
CAGCGGCCGAAAACTTCAGGTTCCAGGCTGCTGTGCGGCTAAATGCGACTCCATCTCCCCCGACCCAAGCGCGTAATGGCCGCTGGCTAT
CTTGGGGGAGCCAGCTGTTGGACTATGCCCCACTGCCAGGAAACAGGCGCCGGAAGGTTCTCTGACAAGATCTCGCTTTCCTAGGGCGGT
GAAGGCGTTCAAAGGTCGGGAAGGGGCGCTGGGAGAAGCGGGGCAGCGCTGAGCCATGCTCGCGAACTGTGGGTCTGTCTGTGAAGAGAC
CCAGTTTCGTGGGACCACGGTGGCGCCTGCGCTGGGAGGTGAGCTTGTGACAGAGCGAAAACTACAATTCCCAGCATTCCTGTGGTGCCA
GAACTACCTTGCCCGAAAGCCTGTGCGAGATTTACCCCGTCTTCCGCCTCCCTCCCACCGGAAAACTCTGAGGACATGAATAGTCGCCAG
GCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCGCCGGCCCTGCGGAGAGGGCTT
CATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGGCTACGTTGGCCATGAGGAGGG
TGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGCCCATCCAGATGTGCTCACCAT
CATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGCCATCTTCATCATGACCTCCAA
TGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAACCGTATTGCCGAAAACCTGGG
GGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCTGAAAGCTCACTTCCGGAGGGA
TGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACTCGTCAACAAGGAACTAAACTT
CTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCTGGTCGACGGCTACAATGTGCA
CTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGAGCAGGACCTGCTGCCAGGGGG
CTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACCCCAGGCTGAGAAGCGCCTCCC
CAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCACCCTGAGAAGGTGTGCAACAC

>13983_13983_8_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000437826_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_9_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000538039_length(transcript)=2368nt_BP=535nt
CAGCGGCCGAAAACTTCAGGTTCCAGGCTGCTGTGCGGCTAAATGCGACTCCATCTCCCCCGACCCAAGCGCGTAATGGCCGCTGGCTAT
CTTGGGGGAGCCAGCTGTTGGACTATGCCCCACTGCCAGGAAACAGGCGCCGGAAGGTTCTCTGACAAGATCTCGCTTTCCTAGGGCGGT
GAAGGCGTTCAAAGGTCGGGAAGGGGCGCTGGGAGAAGCGGGGCAGCGCTGAGCCATGCTCGCGAACTGTGGGTCTGTCTGTGAAGAGAC
CCAGTTTCGTGGGACCACGGTGGCGCCTGCGCTGGGAGGTGAGCTTGTGACAGAGCGAAAACTACAATTCCCAGCATTCCTGTGGTGCCA
GAACTACCTTGCCCGAAAGCCTGTGCGAGATTTACCCCGTCTTCCGCCTCCCTCCCACCGGAAAACTCTGAGGACATGAATAGTCGCCAG
GCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCGCCGGCCCTGCGGAGAGGGCTT
CATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGGCTACGTTGGCCATGAGGAGGG
TGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGCCCATCCAGATGTGCTCACCAT
CATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGCCATCTTCATCATGACCTCCAA
TGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAACCGTATTGCCGAAAACCTGGG
GGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCTGAAAGCTCACTTCCGGAGGGA
TGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACTCGTCAACAAGGAACTAAACTT
CTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCTGGTCGACGGCTACAATGTGCA
CTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGAGCAGGACCTGCTGCCAGGGGG
CTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACCCCAGGCTGAGAAGCGCCTCCC
CAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCACCCTGAGAAGGTGTGCAACAC
CATCTAGCAGCCACCTGCCTGCTCCTATGTGCCCTCACCATCCAATAAAGGCCCCTTGGCTGTGGCATGGCAACTGACTTACCTTCCCCT
CATGCCGCTCCCATCTCTACCCAGTCTCAGGCCTGCTTACCTCCTCACAGCCCATGAAGACCCCTTCTCAGCCCCAAAACCTGAAGGAGG
AATTTCGCCCTACTCTGGCCCCTTTGTTGTGGGCCCATAACCTGCTAACAAGCCTTCAGGAGAGGAGCTGCCTTTCCACCCCCTTCAAGG
CAAGGAGGGATGGAGGTCCCTTATTTCCTTCAGAATGATCCCCATCCCCCATAGTCGCCAGACTTTCTCATGTTCCCAGGAAGCTCAGAA
GTATGGCAGCTAAGAACACAGCTGGCTGGAAGAAGACAGGGACCAGACTGAACTGCCACCCTCTGCTAGTCCTCATGCAACTCAGTCCCC
AGAATGGCTCCACTGGGAGTGGAGGAAGAGCTCAGAGGCCCAGGTGCAGATAGTTCTGCAATTTAGTCTGTAGCCTCCTCGTTCCCTACC
CTAAAATTCTAAGGGGAAGGGACCCATAGAGGCTTGCCTGTTTCCGCTACTATATTATGCCCAGTGTTCCTCCTCACCCCACGTCCTGGG
GTCAGGCCAGACCATGTTTCGTCAGCCTTGGGGACTAGGCCAGTGTTGGGCACCTCCAGGAGGAGGCCTGACTGGTTCATTACCCTCCCC
TACTCAGACTGAGCAGCAGTCCCAGATAACCAAGCAAGCTCAGCTCTGTGGGGGCCTCCTTCAAAAGACCAACATCGCAGACATTAGGAA
GCTGTAGGAAGAGAGATCATGGGTTTGACCTCTGCCCACATGGCCATGGAGTCAGCCTCAGCCCTGTCTGTACTGCTCGTCCAGCTAAAC

>13983_13983_9_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000538039_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------
>13983_13983_10_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000543042_length(transcript)=1505nt_BP=535nt
CAGCGGCCGAAAACTTCAGGTTCCAGGCTGCTGTGCGGCTAAATGCGACTCCATCTCCCCCGACCCAAGCGCGTAATGGCCGCTGGCTAT
CTTGGGGGAGCCAGCTGTTGGACTATGCCCCACTGCCAGGAAACAGGCGCCGGAAGGTTCTCTGACAAGATCTCGCTTTCCTAGGGCGGT
GAAGGCGTTCAAAGGTCGGGAAGGGGCGCTGGGAGAAGCGGGGCAGCGCTGAGCCATGCTCGCGAACTGTGGGTCTGTCTGTGAAGAGAC
CCAGTTTCGTGGGACCACGGTGGCGCCTGCGCTGGGAGGTGAGCTTGTGACAGAGCGAAAACTACAATTCCCAGCATTCCTGTGGTGCCA
GAACTACCTTGCCCGAAAGCCTGTGCGAGATTTACCCCGTCTTCCGCCTCCCTCCCACCGGAAAACTCTGAGGACATGAATAGTCGCCAG
GCTTGGCGGCTCTTTCTCTCCCAAGGCAGAGGAGATCGTTGGGTTTCAAGGCCCCGCGGGCATTTCTCGCCGGCCCTGCGGAGAGGGCTT
CATCAGGCTGGACATGTCCGAGTTCCAGGAGCGACACGAGGTGGCCAAGTTTATTGGGTCTCCACCAGGCTACGTTGGCCATGAGGAGGG
TGGCCAGCTGACCAAGAAGTTGAAGCAGTGCCCCAATGCTGTGGTGCTCTTTGATGAAGTAGACAAGGCCCATCCAGATGTGCTCACCAT
CATGCTGCAGCTGTTTGATGAGGGCCGGCTGACAGATGGAAAAGGGAAGACCATTGATTGCAAGGACGCCATCTTCATCATGACCTCCAA
TGTGGCCAGCGACGAGATCGCACAGCACGCGCTGCAGCTGAGGCAGGAAGCTTTGGAGATGAGCCGTAACCGTATTGCCGAAAACCTGGG
GGATGTCCAGATAAGTGACAAGATCACCATCTCAAAGAACTTCAAGGAGAATGTGATTCGCCCTATCCTGAAAGCTCACTTCCGGAGGGA
TGAGTTTCTGGGACGGATCAATGAGATCGTCTACTTCCTCCCCTTCTGCCACTCGGAGCTCATCCAACTCGTCAACAAGGAACTAAACTT
CTGGGCCAAGAGAGCCAAGCAAAGGCACAACATCACGCTGCTCTGGGACCGCGAGGTGGCAGATGTGCTGGTCGACGGCTACAATGTGCA
CTATGGCGCCCGCTCCATCAAACATGAGGTAGAACGCCGTGTGGTGAACCAGCTGGCAGCAGCCTATGAGCAGGACCTGCTGCCAGGGGG
CTGTACTTTGCGCATCACGGTGGAGGACTCAGACAAGCAGCTACTCAAAAGCCCAGAACTGCCCTCACCCCAGGCTGAGAAGCGCCTCCC
CAAGCTGCGTCTGGAGATCATCGACAAGGACAGCAAGACTCGCAGACTGGACATCCGGGCACCACTGCACCCTGAGAAGGTGTGCAACAC

>13983_13983_10_CCDC90B-CLPB_CCDC90B_chr11_82996916_ENST00000529689_CLPB_chr11_72013392_ENST00000543042_length(amino acids)=299AA_BP=
MDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVA
SDEIAQHALQLRQEALEMSRNRIAENLGDVQISDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWA
KRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKQLLKSPELPSPQAEKRLPKL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CCDC90B-CLPB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCDC90B-CLPB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCDC90B-CLPB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource