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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCNF-NOL4 (FusionGDB2 ID:14139)

Fusion Gene Summary for CCNF-NOL4

check button Fusion gene summary
Fusion gene informationFusion gene name: CCNF-NOL4
Fusion gene ID: 14139
HgeneTgene
Gene symbol

CCNF

NOL4

Gene ID

899

8715

Gene namecyclin Fnucleolar protein 4
SynonymsFBX1|FBXO1CT125|HRIHFB2255|NOLP
Cytomap

16p13.3

18q12.1

Type of geneprotein-codingprotein-coding
Descriptioncyclin-FF-box only protein 1G2/mitotic-specific cyclin-Fnucleolar protein 4cancer/testis antigen 125nucleolar localized protein
Modification date2020031320200313
UniProtAcc

P41002

Q96MY1

Ensembl transtripts involved in fusion geneENST00000397066, ENST00000535384, 
ENST00000535475, ENST00000538587, 
ENST00000589544, ENST00000590846, 
ENST00000261592, ENST00000269185, 
Fusion gene scores* DoF score6 X 6 X 6=2169 X 10 X 5=450
# samples 69
** MAII scorelog2(6/216*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/450*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCNF [Title/Abstract] AND NOL4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCNF(2489827)-NOL4(31673561), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCCNF

GO:0010826

negative regulation of centrosome duplication

20596027

HgeneCCNF

GO:0016567

protein ubiquitination

20596027

HgeneCCNF

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

20596027


check buttonFusion gene breakpoints across CCNF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NOL4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-TM-A84I-01ACCNFchr16

2489826

+NOL4chr18

31673560

-
ChimerDB4LGGTCGA-TM-A84I-01ACCNFchr16

2489827

-NOL4chr18

31673561

-
ChimerDB4LGGTCGA-TM-A84I-01ACCNFchr16

2489827

+NOL4chr18

31673561

-
ChimerDB4LGGTCGA-TM-A84ICCNFchr16

2489827

+NOL4chr18

31673561

-


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Fusion Gene ORF analysis for CCNF-NOL4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000397066ENST00000535384CCNFchr16

2489826

+NOL4chr18

31673560

-
5CDS-intronENST00000397066ENST00000535384CCNFchr16

2489827

+NOL4chr18

31673561

-
5CDS-intronENST00000397066ENST00000535475CCNFchr16

2489826

+NOL4chr18

31673560

-
5CDS-intronENST00000397066ENST00000535475CCNFchr16

2489827

+NOL4chr18

31673561

-
5CDS-intronENST00000397066ENST00000538587CCNFchr16

2489826

+NOL4chr18

31673560

-
5CDS-intronENST00000397066ENST00000538587CCNFchr16

2489827

+NOL4chr18

31673561

-
5CDS-intronENST00000397066ENST00000589544CCNFchr16

2489826

+NOL4chr18

31673560

-
5CDS-intronENST00000397066ENST00000589544CCNFchr16

2489827

+NOL4chr18

31673561

-
5CDS-intronENST00000397066ENST00000590846CCNFchr16

2489826

+NOL4chr18

31673560

-
5CDS-intronENST00000397066ENST00000590846CCNFchr16

2489827

+NOL4chr18

31673561

-
In-frameENST00000397066ENST00000261592CCNFchr16

2489826

+NOL4chr18

31673560

-
In-frameENST00000397066ENST00000261592CCNFchr16

2489827

+NOL4chr18

31673561

-
In-frameENST00000397066ENST00000269185CCNFchr16

2489826

+NOL4chr18

31673560

-
In-frameENST00000397066ENST00000269185CCNFchr16

2489827

+NOL4chr18

31673561

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397066CCNFchr162489827+ENST00000261592NOL4chr1831673561-3885865882142684
ENST00000397066CCNFchr162489827+ENST00000269185NOL4chr1831673561-3572865881836582
ENST00000397066CCNFchr162489826+ENST00000261592NOL4chr1831673560-3885865882142684
ENST00000397066CCNFchr162489826+ENST00000269185NOL4chr1831673560-3572865881836582

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397066ENST00000261592CCNFchr162489827+NOL4chr1831673561-0.0026536250.9973464
ENST00000397066ENST00000269185CCNFchr162489827+NOL4chr1831673561-0.0016761240.99832386
ENST00000397066ENST00000261592CCNFchr162489826+NOL4chr1831673560-0.0026536250.9973464
ENST00000397066ENST00000269185CCNFchr162489826+NOL4chr1831673560-0.0016761240.99832386

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Fusion Genomic Features for CCNF-NOL4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CCNF-NOL4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:2489827/chr18:31673561)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CCNF

P41002

NOL4

Q96MY1

FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. {ECO:0000269|PubMed:20596027}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCNFchr16:2489826chr18:31673560ENST00000397066+81729_76259787.0DomainF-box
HgeneCCNFchr16:2489827chr18:31673561ENST00000397066+81729_76259787.0DomainF-box
HgeneCCNFchr16:2489826chr18:31673560ENST00000397066+81720_28259787.0MotifNuclear localization signal 1
HgeneCCNFchr16:2489827chr18:31673561ENST00000397066+81720_28259787.0MotifNuclear localization signal 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCNFchr16:2489826chr18:31673560ENST00000397066+817292_405259787.0DomainNote=Cyclin N-terminal
HgeneCCNFchr16:2489827chr18:31673561ENST00000397066+817292_405259787.0DomainNote=Cyclin N-terminal
HgeneCCNFchr16:2489826chr18:31673560ENST00000397066+817568_574259787.0MotifNuclear localization signal 2
HgeneCCNFchr16:2489827chr18:31673561ENST00000397066+817568_574259787.0MotifNuclear localization signal 2
HgeneCCNFchr16:2489826chr18:31673560ENST00000397066+817582_766259787.0RegionNote=PEST
HgeneCCNFchr16:2489827chr18:31673561ENST00000397066+817582_766259787.0RegionNote=PEST


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Fusion Gene Sequence for CCNF-NOL4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14139_14139_1_CCNF-NOL4_CCNF_chr16_2489826_ENST00000397066_NOL4_chr18_31673560_ENST00000261592_length(transcript)=3885nt_BP=865nt
CTGCGCCTGCGCGAGGGCTACGCGCGCTCCGGCCGGGGCGCGGGCGCGCTCTCAGGCGGGCTCCGGCGGCAGCGACGCGAGCGCGGCGAT
GGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGTTATCCTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGAC
CATCTTGAGTCTCCCCGAAGATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGAGCTGTACACTCCCA
GCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCCAGCTTCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTT
TGAAAGGGCTGCTGAAAAGGGGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTGTCTGTGTCTGATGA
GGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGTCTCGCTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCT
CTTCATCCGCCCTCCGTGGTCGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGCCAGCTGCAGAGGAC
TCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTGTTCGAGGATGAGGAGAAGCAGCAGCAGGCCCATGACCTGTTTGA
GGAGGCTGCTCATCAGGGATGTCTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGGACAGATGTGTCAGATCCTGGGCGATGCCT
CCACAGCTTCCGAAAACTCAGGGACTACGCTGCCAAAGGCTGCTGGGAAGCGCAGGATGAAAGTTCAATAGAAAGTGATGAATTTGACAT
GAGTGATTCAACACGGATGTCAGCTGTGAACTCTGATCTTAGCTCCAATCTTGAAGAAAGAATGCAAAGTCCCCAGAATCTTCATGGCCA
GCAAGATGATGATTCTGCTGCAGAGAGCTTTAATGGCAATGAGACTCTGGGGCACAGTTCAATTGCTTCAGGGGGAACACACAGCAGGGA
GATGGGAGACTCCAACAGTGATGGCAAAACTGGGCTGGAGCAAGATGAACAGCCACTGAACCTGAGTGACAGTCCCCTCTCTGCGCAGCT
AACTTCGGAATACAGAATAGATGATCACAACAGTAATGGGAAAAACAAGTATAAGAATCTTCTAATTTCTGACCTCAAGATGGAACGAGA
GGCGAGAGAAAATGGAAGCAAGTCTCCTGCACATAGTTACTCCAGCTATGACTCTGGCAAAAATGAGAGTGTAGACCGAGGAGCTGAGGA
CCTCTCACTAAACAGGGGAGATGAGGACGAAGATGACCACGAGGACCATGACGATTCGGAGAAAGTTAATGAGACAGACGGCGTTGAAGC
CGAGCGGCTGAAAGCTTTTAATATGTTTGTCAGGCTGTTTGTAGATGAAAACTTGGACCGAATGGTCCCAATCTCTAAGCAGCCCAAAGA
AAAGATCCAGGCTATCATTGACTCATGCAGGCGACAATTCCCTGAGTATCAAGAGCGTGCCAGAAAACGTATACGTACTTACCTCAAGTC
CTGCAGGCGGATGAAAAGAAGTGGTTTTGAGATGTCTCGACCTATTCCTTCCCACCTTACTTCAGCAGTTGCAGAGAGTATCTTGGCTTC
AGCTTGTGAGAGTGAGAGTAGAAATGCCGCCAAGAGGATGCGTCTGGAGAGACAGCAGGATGAGTCTGCTCCAGCTGACAAACAGTGTAA
ACCAGAGGCGACCCAGGCCACTTACTCAACATCAGCTGTTCCAGGCTCACAGGACGTGCTGTACATCAATGGAAATGGGACCTATAGTTA
CCATAGTTACAGAGGGCTAGGAGGGGGTCTGCTAAATCTGAATGATGCTTCCAGCAGTGGACCCACTGATCTCAGCATGAAGAGACAATT
GGCGACTAGCTCAGGATCCTCCAGCAGCTCAAACTCCAGACCCCAGCTGAGTCCAACTGAAATCAATGCCGTGAGACAGCTTGTTGCAGG
ATATCGAGAATCAGCTGCATTTTTATTGCGATCTGCAGATGAACTGGAAAATCTCATTTTACAACAGAACTGAGACAGACGACCACCATA
TTCACTGAGGTCTAAATTTGCAGTTTCCACTAATGACATTTTGATTTCCCAACAGAGATACTTCTGGTCTTACTGCACAGTCTTTTAAGA
GAAATACTTCCATTATGCCACATTGTCCTTGATCCGTAAGTGATGTGTTAAGGTGCTTCAAAGGAACTCTGACCTCTGAAGTACTTGAGC
TACTTTAGTATGTCCAGCCTATTGCTTTTTGTTTTAGTGTGTCACCATAAATATCAGGGGCATAAAAGGCTATCTATTCTTAATTCAAGG
ATAAAACAGAAGAAGCTTGTGGTATAAAACAATAGTTCAAGATCCAGCTGAAATATTAGTGGAATTTGCTACTGACTCATTGGACTGAAA
GCTGAAGTACCTGGCAAAAAAAAAAAAAAGAAAAAAAAAAGCCAAATTTCTTGTTGCTACAGGATATAACAACAATGAAAAGGATCTCGT
ATTTTAAAAAAATATGTAATTTTTATAAAAAGAAAACTTGTTTTTCATTCAAACTTGTCATTTTTACTTTGGTAACTTTTTCATAGGTCC
TAAAAGAAAACTGTTTTGAGAAACTACTGTAAGTACCTTTTCCACATCCCTTTGCCTTCTCCTCTTTCCAAATTCTTTCTACAAAAATAA
CACTTGATGCTGGAAAAACCCTTGCCTACGTTCTTTCAATCGTCACATCAGGAACTACTTCCAAGAGAAGCCTGCATTTCTGCTCTCATG
CTGATCTCAAAAACCCCACTCAACACTGCAACTTTATCATAGCAGTTTTCATCCCAGAATTTTTTTTTTAATAATGACAAGACATGTTGT
TGAAAAAAAATCACACCTTGGTTTCTTAGAGCTGCTCGTTCCTGATTGCCGCTGCTGTCTCCAGGCATCCCTCTAGCAGCACCTGGATGT
AGATGACTGAATGTTAAGAGGTTGCAAGTGACAATCTGAAAATTTGCACTCTTGTGTGTAGTTTTCTTTTCATTTCTTTCAGAAATAGTT
TCCAAAAAGACCATTACATCTCCTGATATGATTTGTATAATTTTCAGTTCTAGCTAAAAATAATGTAAGGAACTCTCAGCGGATGCAGCT
GCAACTTACAATGAACTGTGCCCTCCTATCCCCCATACTTTACCCTTCTTTCTTATTTTATAGTGTGGGATACACATGAGTGATGTTTTC
TTTGTGCACTGAGACAAGCCTATTTTTTAAATATTTAGGGAGAAGTACTTTAGTTCATGCTTCTTATACAACTTTTTTCTGTTGTTTAGC
TTTGGTTGGATTACAAATTCTTTGTGCATTCCTGAATTTGCCTTATTTCATGTAAAATTTATGTCATTCAGTTTTTGACAATGAGTTTGA
GGCATCAGTGATATTTCTTATCTACTTGTTACATATAGTTTTTCAAGTAATGACTGTGATTGTGACCGAGTAATGTGCACTTTTTCTTGT
AACTGTGGACATTGCTATGCTTTTTTCTTCTAGTGTTTCTAGAATTACTGTTCCTTACAATTATGTAAACAAAAAACAAAAAAAAAACTT
TTGTGATACTGTTGGTGAATATAATGTGAAAAATCTTATTGAAATATGAGTATTTTGGAAATACATAGCTGCACAAACATCTTTTAAGAT
GTGGATTTAGAGTTTGCTTATTTAAATGAAAATTCAAAAATTGAGGGCTGGTATAATTTTCTCTGTTTTGTTTGGTTTAATAAACAGATT

>14139_14139_1_CCNF-NOL4_CCNF_chr16_2489826_ENST00000397066_NOL4_chr18_31673560_ENST00000261592_length(amino acids)=684AA_BP=258
MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKL
FERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQDESSIESDEFD
MSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ
LTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVE
AERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILA
SACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQ

--------------------------------------------------------------
>14139_14139_2_CCNF-NOL4_CCNF_chr16_2489826_ENST00000397066_NOL4_chr18_31673560_ENST00000269185_length(transcript)=3572nt_BP=865nt
CTGCGCCTGCGCGAGGGCTACGCGCGCTCCGGCCGGGGCGCGGGCGCGCTCTCAGGCGGGCTCCGGCGGCAGCGACGCGAGCGCGGCGAT
GGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGTTATCCTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGAC
CATCTTGAGTCTCCCCGAAGATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGAGCTGTACACTCCCA
GCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCCAGCTTCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTT
TGAAAGGGCTGCTGAAAAGGGGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTGTCTGTGTCTGATGA
GGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGTCTCGCTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCT
CTTCATCCGCCCTCCGTGGTCGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGCCAGCTGCAGAGGAC
TCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTGTTCGAGGATGAGGAGAAGCAGCAGCAGGCCCATGACCTGTTTGA
GGAGGCTGCTCATCAGGGATGTCTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGGACAGATGTGTCAGATCCTGGGCGATGCCT
CCACAGCTTCCGAAAACTCAGGGACTACGCTGCCAAAGGCTGCTGGGAAGCGCAGGATGAAAGTTCAATAGAAAGTGATGAATTTGACAT
GAGTGATTCAACACGGATGTCAGCTGTGAACTCTGATCTTAGCTCCAATCTTGAAGAAAGAATGCAAAGTCCCCAGAATCTTCATGGCCA
GCAAGATGATGATTCTGCTGCAGAGAGCTTTAATGGCAATGAGACTCTGGGGCACAGTTCAATTGCTTCAGGGGGAACACACAGCAGGGA
GATGGGAGACTCCAACAGTGATGGCAAAACTGGGCTGGAGCAAGATGAACAGCCACTGAACCTGAGTGACAGTCCCCTCTCTGCGCAGCT
AACTTCGGAATACAGAATAGATGATCACAACAGTAATGGGAAAAACAAGTATAAGAATCTTCTAATTTCTGACCTCAAGATGGAACGAGA
GGCGAGAGAAAATGGAAGCAAGTCTCCTGCACATAGTTACTCCAGCTATGACTCTGGCAAAAATGAGAGTGTAGACCGAGGAGCTGAGGA
CCTCTCACTAAACAGGGGAGATGAGGACGAAGATGACCACGAGGACCATGACGATTCGGAGAAAGTTAATGAGACAGACGGCGTTGAAGC
CGAGCGGCTGAAAGCTTTTAATGATGAGTCTGCTCCAGCTGACAAACAGTGTAAACCAGAGGCGACCCAGGCCACTTACTCAACATCAGC
TGTTCCAGGCTCACAGGACGTGCTGTACATCAATGGAAATGGGACCTATAGTTACCATAGTTACAGAGGGCTAGGAGGGGGTCTGCTAAA
TCTGAATGATGCTTCCAGCAGTGGACCCACTGATCTCAGCATGAAGAGACAATTGGCGACTAGCTCAGGATCCTCCAGCAGCTCAAACTC
CAGACCCCAGCTGAGTCCAACTGAAATCAATGCCGTGAGACAGCTTGTTGCAGGATATCGAGAATCAGCTGCATTTTTATTGCGATCTGC
AGATGAACTGGAAAATCTCATTTTACAACAGAACTGAGACAGACGACCACCATATTCACTGAGGTCTAAATTTGCAGTTTCCACTAATGA
CATTTTGATTTCCCAACAGAGATACTTCTGGTCTTACTGCACAGTCTTTTAAGAGAAATACTTCCATTATGCCACATTGTCCTTGATCCG
TAAGTGATGTGTTAAGGTGCTTCAAAGGAACTCTGACCTCTGAAGTACTTGAGCTACTTTAGTATGTCCAGCCTATTGCTTTTTGTTTTA
GTGTGTCACCATAAATATCAGGGGCATAAAAGGCTATCTATTCTTAATTCAAGGATAAAACAGAAGAAGCTTGTGGTATAAAACAATAGT
TCAAGATCCAGCTGAAATATTAGTGGAATTTGCTACTGACTCATTGGACTGAAAGCTGAAGTACCTGGCAAAAAAAAAAAAAAGAAAAAA
AAAAGCCAAATTTCTTGTTGCTACAGGATATAACAACAATGAAAAGGATCTCGTATTTTAAAAAAATATGTAATTTTTATAAAAAGAAAA
CTTGTTTTTCATTCAAACTTGTCATTTTTACTTTGGTAACTTTTTCATAGGTCCTAAAAGAAAACTGTTTTGAGAAACTACTGTAAGTAC
CTTTTCCACATCCCTTTGCCTTCTCCTCTTTCCAAATTCTTTCTACAAAAATAACACTTGATGCTGGAAAAACCCTTGCCTACGTTCTTT
CAATCGTCACATCAGGAACTACTTCCAAGAGAAGCCTGCATTTCTGCTCTCATGCTGATCTCAAAAACCCCACTCAACACTGCAACTTTA
TCATAGCAGTTTTCATCCCAGAATTTTTTTTTTAATAATGACAAGACATGTTGTTGAAAAAAAATCACACCTTGGTTTCTTAGAGCTGCT
CGTTCCTGATTGCCGCTGCTGTCTCCAGGCATCCCTCTAGCAGCACCTGGATGTAGATGACTGAATGTTAAGAGGTTGCAAGTGACAATC
TGAAAATTTGCACTCTTGTGTGTAGTTTTCTTTTCATTTCTTTCAGAAATAGTTTCCAAAAAGACCATTACATCTCCTGATATGATTTGT
ATAATTTTCAGTTCTAGCTAAAAATAATGTAAGGAACTCTCAGCGGATGCAGCTGCAACTTACAATGAACTGTGCCCTCCTATCCCCCAT
ACTTTACCCTTCTTTCTTATTTTATAGTGTGGGATACACATGAGTGATGTTTTCTTTGTGCACTGAGACAAGCCTATTTTTTAAATATTT
AGGGAGAAGTACTTTAGTTCATGCTTCTTATACAACTTTTTTCTGTTGTTTAGCTTTGGTTGGATTACAAATTCTTTGTGCATTCCTGAA
TTTGCCTTATTTCATGTAAAATTTATGTCATTCAGTTTTTGACAATGAGTTTGAGGCATCAGTGATATTTCTTATCTACTTGTTACATAT
AGTTTTTCAAGTAATGACTGTGATTGTGACCGAGTAATGTGCACTTTTTCTTGTAACTGTGGACATTGCTATGCTTTTTTCTTCTAGTGT
TTCTAGAATTACTGTTCCTTACAATTATGTAAACAAAAAACAAAAAAAAAACTTTTGTGATACTGTTGGTGAATATAATGTGAAAAATCT
TATTGAAATATGAGTATTTTGGAAATACATAGCTGCACAAACATCTTTTAAGATGTGGATTTAGAGTTTGCTTATTTAAATGAAAATTCA

>14139_14139_2_CCNF-NOL4_CCNF_chr16_2489826_ENST00000397066_NOL4_chr18_31673560_ENST00000269185_length(amino acids)=582AA_BP=258
MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKL
FERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQDESSIESDEFD
MSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ
LTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVE
AERLKAFNDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSN

--------------------------------------------------------------
>14139_14139_3_CCNF-NOL4_CCNF_chr16_2489827_ENST00000397066_NOL4_chr18_31673561_ENST00000261592_length(transcript)=3885nt_BP=865nt
CTGCGCCTGCGCGAGGGCTACGCGCGCTCCGGCCGGGGCGCGGGCGCGCTCTCAGGCGGGCTCCGGCGGCAGCGACGCGAGCGCGGCGAT
GGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGTTATCCTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGAC
CATCTTGAGTCTCCCCGAAGATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGAGCTGTACACTCCCA
GCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCCAGCTTCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTT
TGAAAGGGCTGCTGAAAAGGGGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTGTCTGTGTCTGATGA
GGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGTCTCGCTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCT
CTTCATCCGCCCTCCGTGGTCGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGCCAGCTGCAGAGGAC
TCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTGTTCGAGGATGAGGAGAAGCAGCAGCAGGCCCATGACCTGTTTGA
GGAGGCTGCTCATCAGGGATGTCTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGGACAGATGTGTCAGATCCTGGGCGATGCCT
CCACAGCTTCCGAAAACTCAGGGACTACGCTGCCAAAGGCTGCTGGGAAGCGCAGGATGAAAGTTCAATAGAAAGTGATGAATTTGACAT
GAGTGATTCAACACGGATGTCAGCTGTGAACTCTGATCTTAGCTCCAATCTTGAAGAAAGAATGCAAAGTCCCCAGAATCTTCATGGCCA
GCAAGATGATGATTCTGCTGCAGAGAGCTTTAATGGCAATGAGACTCTGGGGCACAGTTCAATTGCTTCAGGGGGAACACACAGCAGGGA
GATGGGAGACTCCAACAGTGATGGCAAAACTGGGCTGGAGCAAGATGAACAGCCACTGAACCTGAGTGACAGTCCCCTCTCTGCGCAGCT
AACTTCGGAATACAGAATAGATGATCACAACAGTAATGGGAAAAACAAGTATAAGAATCTTCTAATTTCTGACCTCAAGATGGAACGAGA
GGCGAGAGAAAATGGAAGCAAGTCTCCTGCACATAGTTACTCCAGCTATGACTCTGGCAAAAATGAGAGTGTAGACCGAGGAGCTGAGGA
CCTCTCACTAAACAGGGGAGATGAGGACGAAGATGACCACGAGGACCATGACGATTCGGAGAAAGTTAATGAGACAGACGGCGTTGAAGC
CGAGCGGCTGAAAGCTTTTAATATGTTTGTCAGGCTGTTTGTAGATGAAAACTTGGACCGAATGGTCCCAATCTCTAAGCAGCCCAAAGA
AAAGATCCAGGCTATCATTGACTCATGCAGGCGACAATTCCCTGAGTATCAAGAGCGTGCCAGAAAACGTATACGTACTTACCTCAAGTC
CTGCAGGCGGATGAAAAGAAGTGGTTTTGAGATGTCTCGACCTATTCCTTCCCACCTTACTTCAGCAGTTGCAGAGAGTATCTTGGCTTC
AGCTTGTGAGAGTGAGAGTAGAAATGCCGCCAAGAGGATGCGTCTGGAGAGACAGCAGGATGAGTCTGCTCCAGCTGACAAACAGTGTAA
ACCAGAGGCGACCCAGGCCACTTACTCAACATCAGCTGTTCCAGGCTCACAGGACGTGCTGTACATCAATGGAAATGGGACCTATAGTTA
CCATAGTTACAGAGGGCTAGGAGGGGGTCTGCTAAATCTGAATGATGCTTCCAGCAGTGGACCCACTGATCTCAGCATGAAGAGACAATT
GGCGACTAGCTCAGGATCCTCCAGCAGCTCAAACTCCAGACCCCAGCTGAGTCCAACTGAAATCAATGCCGTGAGACAGCTTGTTGCAGG
ATATCGAGAATCAGCTGCATTTTTATTGCGATCTGCAGATGAACTGGAAAATCTCATTTTACAACAGAACTGAGACAGACGACCACCATA
TTCACTGAGGTCTAAATTTGCAGTTTCCACTAATGACATTTTGATTTCCCAACAGAGATACTTCTGGTCTTACTGCACAGTCTTTTAAGA
GAAATACTTCCATTATGCCACATTGTCCTTGATCCGTAAGTGATGTGTTAAGGTGCTTCAAAGGAACTCTGACCTCTGAAGTACTTGAGC
TACTTTAGTATGTCCAGCCTATTGCTTTTTGTTTTAGTGTGTCACCATAAATATCAGGGGCATAAAAGGCTATCTATTCTTAATTCAAGG
ATAAAACAGAAGAAGCTTGTGGTATAAAACAATAGTTCAAGATCCAGCTGAAATATTAGTGGAATTTGCTACTGACTCATTGGACTGAAA
GCTGAAGTACCTGGCAAAAAAAAAAAAAAGAAAAAAAAAAGCCAAATTTCTTGTTGCTACAGGATATAACAACAATGAAAAGGATCTCGT
ATTTTAAAAAAATATGTAATTTTTATAAAAAGAAAACTTGTTTTTCATTCAAACTTGTCATTTTTACTTTGGTAACTTTTTCATAGGTCC
TAAAAGAAAACTGTTTTGAGAAACTACTGTAAGTACCTTTTCCACATCCCTTTGCCTTCTCCTCTTTCCAAATTCTTTCTACAAAAATAA
CACTTGATGCTGGAAAAACCCTTGCCTACGTTCTTTCAATCGTCACATCAGGAACTACTTCCAAGAGAAGCCTGCATTTCTGCTCTCATG
CTGATCTCAAAAACCCCACTCAACACTGCAACTTTATCATAGCAGTTTTCATCCCAGAATTTTTTTTTTAATAATGACAAGACATGTTGT
TGAAAAAAAATCACACCTTGGTTTCTTAGAGCTGCTCGTTCCTGATTGCCGCTGCTGTCTCCAGGCATCCCTCTAGCAGCACCTGGATGT
AGATGACTGAATGTTAAGAGGTTGCAAGTGACAATCTGAAAATTTGCACTCTTGTGTGTAGTTTTCTTTTCATTTCTTTCAGAAATAGTT
TCCAAAAAGACCATTACATCTCCTGATATGATTTGTATAATTTTCAGTTCTAGCTAAAAATAATGTAAGGAACTCTCAGCGGATGCAGCT
GCAACTTACAATGAACTGTGCCCTCCTATCCCCCATACTTTACCCTTCTTTCTTATTTTATAGTGTGGGATACACATGAGTGATGTTTTC
TTTGTGCACTGAGACAAGCCTATTTTTTAAATATTTAGGGAGAAGTACTTTAGTTCATGCTTCTTATACAACTTTTTTCTGTTGTTTAGC
TTTGGTTGGATTACAAATTCTTTGTGCATTCCTGAATTTGCCTTATTTCATGTAAAATTTATGTCATTCAGTTTTTGACAATGAGTTTGA
GGCATCAGTGATATTTCTTATCTACTTGTTACATATAGTTTTTCAAGTAATGACTGTGATTGTGACCGAGTAATGTGCACTTTTTCTTGT
AACTGTGGACATTGCTATGCTTTTTTCTTCTAGTGTTTCTAGAATTACTGTTCCTTACAATTATGTAAACAAAAAACAAAAAAAAAACTT
TTGTGATACTGTTGGTGAATATAATGTGAAAAATCTTATTGAAATATGAGTATTTTGGAAATACATAGCTGCACAAACATCTTTTAAGAT
GTGGATTTAGAGTTTGCTTATTTAAATGAAAATTCAAAAATTGAGGGCTGGTATAATTTTCTCTGTTTTGTTTGGTTTAATAAACAGATT

>14139_14139_3_CCNF-NOL4_CCNF_chr16_2489827_ENST00000397066_NOL4_chr18_31673561_ENST00000261592_length(amino acids)=684AA_BP=258
MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKL
FERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQDESSIESDEFD
MSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ
LTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVE
AERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILA
SACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQ

--------------------------------------------------------------
>14139_14139_4_CCNF-NOL4_CCNF_chr16_2489827_ENST00000397066_NOL4_chr18_31673561_ENST00000269185_length(transcript)=3572nt_BP=865nt
CTGCGCCTGCGCGAGGGCTACGCGCGCTCCGGCCGGGGCGCGGGCGCGCTCTCAGGCGGGCTCCGGCGGCAGCGACGCGAGCGCGGCGAT
GGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGTTATCCTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGAC
CATCTTGAGTCTCCCCGAAGATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGAGCTGTACACTCCCA
GCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCCAGCTTCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTT
TGAAAGGGCTGCTGAAAAGGGGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTGTCTGTGTCTGATGA
GGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGTCTCGCTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCT
CTTCATCCGCCCTCCGTGGTCGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGCCAGCTGCAGAGGAC
TCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTGTTCGAGGATGAGGAGAAGCAGCAGCAGGCCCATGACCTGTTTGA
GGAGGCTGCTCATCAGGGATGTCTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGGACAGATGTGTCAGATCCTGGGCGATGCCT
CCACAGCTTCCGAAAACTCAGGGACTACGCTGCCAAAGGCTGCTGGGAAGCGCAGGATGAAAGTTCAATAGAAAGTGATGAATTTGACAT
GAGTGATTCAACACGGATGTCAGCTGTGAACTCTGATCTTAGCTCCAATCTTGAAGAAAGAATGCAAAGTCCCCAGAATCTTCATGGCCA
GCAAGATGATGATTCTGCTGCAGAGAGCTTTAATGGCAATGAGACTCTGGGGCACAGTTCAATTGCTTCAGGGGGAACACACAGCAGGGA
GATGGGAGACTCCAACAGTGATGGCAAAACTGGGCTGGAGCAAGATGAACAGCCACTGAACCTGAGTGACAGTCCCCTCTCTGCGCAGCT
AACTTCGGAATACAGAATAGATGATCACAACAGTAATGGGAAAAACAAGTATAAGAATCTTCTAATTTCTGACCTCAAGATGGAACGAGA
GGCGAGAGAAAATGGAAGCAAGTCTCCTGCACATAGTTACTCCAGCTATGACTCTGGCAAAAATGAGAGTGTAGACCGAGGAGCTGAGGA
CCTCTCACTAAACAGGGGAGATGAGGACGAAGATGACCACGAGGACCATGACGATTCGGAGAAAGTTAATGAGACAGACGGCGTTGAAGC
CGAGCGGCTGAAAGCTTTTAATGATGAGTCTGCTCCAGCTGACAAACAGTGTAAACCAGAGGCGACCCAGGCCACTTACTCAACATCAGC
TGTTCCAGGCTCACAGGACGTGCTGTACATCAATGGAAATGGGACCTATAGTTACCATAGTTACAGAGGGCTAGGAGGGGGTCTGCTAAA
TCTGAATGATGCTTCCAGCAGTGGACCCACTGATCTCAGCATGAAGAGACAATTGGCGACTAGCTCAGGATCCTCCAGCAGCTCAAACTC
CAGACCCCAGCTGAGTCCAACTGAAATCAATGCCGTGAGACAGCTTGTTGCAGGATATCGAGAATCAGCTGCATTTTTATTGCGATCTGC
AGATGAACTGGAAAATCTCATTTTACAACAGAACTGAGACAGACGACCACCATATTCACTGAGGTCTAAATTTGCAGTTTCCACTAATGA
CATTTTGATTTCCCAACAGAGATACTTCTGGTCTTACTGCACAGTCTTTTAAGAGAAATACTTCCATTATGCCACATTGTCCTTGATCCG
TAAGTGATGTGTTAAGGTGCTTCAAAGGAACTCTGACCTCTGAAGTACTTGAGCTACTTTAGTATGTCCAGCCTATTGCTTTTTGTTTTA
GTGTGTCACCATAAATATCAGGGGCATAAAAGGCTATCTATTCTTAATTCAAGGATAAAACAGAAGAAGCTTGTGGTATAAAACAATAGT
TCAAGATCCAGCTGAAATATTAGTGGAATTTGCTACTGACTCATTGGACTGAAAGCTGAAGTACCTGGCAAAAAAAAAAAAAAGAAAAAA
AAAAGCCAAATTTCTTGTTGCTACAGGATATAACAACAATGAAAAGGATCTCGTATTTTAAAAAAATATGTAATTTTTATAAAAAGAAAA
CTTGTTTTTCATTCAAACTTGTCATTTTTACTTTGGTAACTTTTTCATAGGTCCTAAAAGAAAACTGTTTTGAGAAACTACTGTAAGTAC
CTTTTCCACATCCCTTTGCCTTCTCCTCTTTCCAAATTCTTTCTACAAAAATAACACTTGATGCTGGAAAAACCCTTGCCTACGTTCTTT
CAATCGTCACATCAGGAACTACTTCCAAGAGAAGCCTGCATTTCTGCTCTCATGCTGATCTCAAAAACCCCACTCAACACTGCAACTTTA
TCATAGCAGTTTTCATCCCAGAATTTTTTTTTTAATAATGACAAGACATGTTGTTGAAAAAAAATCACACCTTGGTTTCTTAGAGCTGCT
CGTTCCTGATTGCCGCTGCTGTCTCCAGGCATCCCTCTAGCAGCACCTGGATGTAGATGACTGAATGTTAAGAGGTTGCAAGTGACAATC
TGAAAATTTGCACTCTTGTGTGTAGTTTTCTTTTCATTTCTTTCAGAAATAGTTTCCAAAAAGACCATTACATCTCCTGATATGATTTGT
ATAATTTTCAGTTCTAGCTAAAAATAATGTAAGGAACTCTCAGCGGATGCAGCTGCAACTTACAATGAACTGTGCCCTCCTATCCCCCAT
ACTTTACCCTTCTTTCTTATTTTATAGTGTGGGATACACATGAGTGATGTTTTCTTTGTGCACTGAGACAAGCCTATTTTTTAAATATTT
AGGGAGAAGTACTTTAGTTCATGCTTCTTATACAACTTTTTTCTGTTGTTTAGCTTTGGTTGGATTACAAATTCTTTGTGCATTCCTGAA
TTTGCCTTATTTCATGTAAAATTTATGTCATTCAGTTTTTGACAATGAGTTTGAGGCATCAGTGATATTTCTTATCTACTTGTTACATAT
AGTTTTTCAAGTAATGACTGTGATTGTGACCGAGTAATGTGCACTTTTTCTTGTAACTGTGGACATTGCTATGCTTTTTTCTTCTAGTGT
TTCTAGAATTACTGTTCCTTACAATTATGTAAACAAAAAACAAAAAAAAAACTTTTGTGATACTGTTGGTGAATATAATGTGAAAAATCT
TATTGAAATATGAGTATTTTGGAAATACATAGCTGCACAAACATCTTTTAAGATGTGGATTTAGAGTTTGCTTATTTAAATGAAAATTCA

>14139_14139_4_CCNF-NOL4_CCNF_chr16_2489827_ENST00000397066_NOL4_chr18_31673561_ENST00000269185_length(amino acids)=582AA_BP=258
MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKL
FERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQDESSIESDEFD
MSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQ
LTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVE
AERLKAFNDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CCNF-NOL4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCNF-NOL4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCNF-NOL4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource