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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCT5-SOS2 (FusionGDB2 ID:14331)

Fusion Gene Summary for CCT5-SOS2

check button Fusion gene summary
Fusion gene informationFusion gene name: CCT5-SOS2
Fusion gene ID: 14331
HgeneTgene
Gene symbol

CCT5

SOS2

Gene ID

22948

6655

Gene namechaperonin containing TCP1 subunit 5SOS Ras/Rho guanine nucleotide exchange factor 2
SynonymsCCT-epsilon|CCTE|HEL-S-69|PNAS-102|TCP-1-epsilonNS9|SOS-2
Cytomap

5p15.2

14q21.3

Type of geneprotein-codingprotein-coding
DescriptionT-complex protein 1 subunit epsilonchaperonin containing TCP1, subunit 5 (epsilon)epididymis secretory protein Li 69son of sevenless homolog 2guanine nucleotide releasing factor
Modification date2020031320200327
UniProtAcc

P48643

.
Ensembl transtripts involved in fusion geneENST00000280326, ENST00000503026, 
ENST00000506600, ENST00000515390, 
ENST00000515676, 		ENST00000555794, 
ENST00000216373, ENST00000543680, 
Fusion gene scores* DoF score6 X 9 X 5=27013 X 13 X 9=1521
# samples 917
** MAII scorelog2(9/270*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1521*10)=-3.16141350158679
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CCT5 [Title/Abstract] AND SOS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCT5(10263426)-SOS2(50625364), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CCT5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SOS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR315439CCT5chr5

10263426

+SOS2chr14

50625364

-


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Fusion Gene ORF analysis for CCT5-SOS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000280326ENST00000555794CCT5chr5

10263426

+SOS2chr14

50625364

-
5CDS-5UTRENST00000503026ENST00000555794CCT5chr5

10263426

+SOS2chr14

50625364

-
5CDS-5UTRENST00000506600ENST00000555794CCT5chr5

10263426

+SOS2chr14

50625364

-
5CDS-5UTRENST00000515390ENST00000555794CCT5chr5

10263426

+SOS2chr14

50625364

-
5CDS-5UTRENST00000515676ENST00000555794CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000280326ENST00000216373CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000280326ENST00000543680CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000503026ENST00000216373CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000503026ENST00000543680CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000506600ENST00000216373CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000506600ENST00000543680CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000515390ENST00000216373CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000515390ENST00000543680CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000515676ENST00000216373CCT5chr5

10263426

+SOS2chr14

50625364

-
In-frameENST00000515676ENST00000543680CCT5chr5

10263426

+SOS2chr14

50625364

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000280326CCT5chr510263426+ENST00000216373SOS2chr1450625364-5280191839040641224
ENST00000280326CCT5chr510263426+ENST00000543680SOS2chr1450625364-4099191839040641224
ENST00000503026CCT5chr510263426+ENST00000216373SOS2chr1450625364-487215107536561193
ENST00000503026CCT5chr510263426+ENST00000543680SOS2chr1450625364-369115107536561193
ENST00000515390CCT5chr510263426+ENST00000216373SOS2chr1450625364-482014589536041169
ENST00000515390CCT5chr510263426+ENST00000543680SOS2chr1450625364-363914589536041169
ENST00000515676CCT5chr510263426+ENST00000216373SOS2chr1450625364-5112175034238961184
ENST00000515676CCT5chr510263426+ENST00000543680SOS2chr1450625364-3931175034238961184
ENST00000506600CCT5chr510263426+ENST00000216373SOS2chr1450625364-4945158334037291129
ENST00000506600CCT5chr510263426+ENST00000543680SOS2chr1450625364-3764158334037291129

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000280326ENST00000216373CCT5chr510263426+SOS2chr1450625364-0.0001742550.9998258
ENST00000280326ENST00000543680CCT5chr510263426+SOS2chr1450625364-0.0004449210.99955505
ENST00000503026ENST00000216373CCT5chr510263426+SOS2chr1450625364-0.0001375320.99986243
ENST00000503026ENST00000543680CCT5chr510263426+SOS2chr1450625364-0.0003978370.99960214
ENST00000515390ENST00000216373CCT5chr510263426+SOS2chr1450625364-0.0001534710.99984646
ENST00000515390ENST00000543680CCT5chr510263426+SOS2chr1450625364-0.0004597910.9995402
ENST00000515676ENST00000216373CCT5chr510263426+SOS2chr1450625364-0.0001827110.9998173
ENST00000515676ENST00000543680CCT5chr510263426+SOS2chr1450625364-0.0005162890.9994837
ENST00000506600ENST00000216373CCT5chr510263426+SOS2chr1450625364-0.0001882220.9998118
ENST00000506600ENST00000543680CCT5chr510263426+SOS2chr1450625364-0.0004971490.9995029

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Fusion Genomic Features for CCT5-SOS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CCT5-SOS2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:10263426/chr14:50625364)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CCT5

P48643

.
FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable). {ECO:0000269|PubMed:20080638, ECO:0000269|PubMed:25467444, ECO:0000305}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSOS2chr5:10263426chr14:50625364ENST000002163739231180_11836171333.0Compositional biasNote=Poly-Pro
TgeneSOS2chr5:10263426chr14:50625364ENST000002163739231203_12086171333.0Compositional biasNote=Poly-Pro
TgeneSOS2chr5:10263426chr14:50625364ENST00000216373923755_7586171333.0Compositional biasNote=Poly-Pro
TgeneSOS2chr5:10263426chr14:50625364ENST00000216373923778_10176171333.0DomainRas-GEF

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSOS2chr5:10263426chr14:50625364ENST00000216373923198_3886171333.0DomainDH
TgeneSOS2chr5:10263426chr14:50625364ENST00000216373923442_5466171333.0DomainPH
TgeneSOS2chr5:10263426chr14:50625364ENST00000216373923595_7396171333.0DomainN-terminal Ras-GEF


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Fusion Gene Sequence for CCT5-SOS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14331_14331_1_CCT5-SOS2_CCT5_chr5_10263426_ENST00000280326_SOS2_chr14_50625364_ENST00000216373_length(transcript)=5280nt_BP=1918nt
AAAAAAAAAAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATT
CCTCCTTGGGACCCACTATCGAGAAACTATCAGTGGTAACGTTTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGA
TTTCCACTAAGTGTCTTCAAACCTCCCCCTCCCCGGCTTCCTGGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTG
GCGTGAAATTAGTCTCAGTAGAAACATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTG
CATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGAT
GAATATGGGCGCCCTTTCCTCATCATCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCA
GCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTA
ACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGAT
GAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCA
ATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAG
GACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTG
AATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAG
GACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATT
CTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATAC
GAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCA
AATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGG
ATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAA
ATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGA
TCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCC
CTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATG
GCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGC
ATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTG
CTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATC
AGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCAT
TTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTA
GAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCA
ATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTT
TTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAAT
TTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCA
GTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCA
GTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGAT
CACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACC
GAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAA
ATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCA
TCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAA
TCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCA
TTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACA
CCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTT
GCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCT
CTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGA
CAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCA
AGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCA
CTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCA
AGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCA
AGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCA
GAAACTCCCCAATGACCTTAGCCATATGTAGTCATTGACACTGGAATGGTATTTGTAAAGTTTTTTTTTTAATTTATTCAAAAAAAGACA
TAGTATTTTAGTACTTTTTACAAATAATGCTCTTACAAAAATGCTACTGATCAAATAAGCTTTTAAGAATTGGAAAAATAAAAATACAAA
AGTCCTTCACCATTATCCTCAGGTGATCAGTAGCATTGCCTTGTCTTGGATCCTCAGTGCTGCCAAAAGGCCAGTATAAAGAATTTATAT
TTGCACTGTAAACTCTGCAAAAATATGGTTTAAAGTGACATGATTGCACTGAAAAGGGATAGTGCTTTTGTGAAATTTTTCAAATTTGAG
TAATAGATGCCTTTTTAAGGCAGTGAATTTACACAAATATGGGAGGGGTATATGGTGTTACTGATTTTTAAACCTCTTTGACCATCTTCT
AGTTTTTACTTCTAGTTTTTACATCTAGGAGAATTGTGAATAACACCAACTGTTCTTAAACTCTTTAATGCCATGTCTTAAATGCCGGTA
TTTGCTGCTGAAGACAAAAATGAAAAGTAGGATGAAAATAATAGAATGGCACTGTAAGTGTTTATTATTTTGTCAAAATGTAAACAAAGA
CTACATAACCCAATGATGGAGGGAAAAAGGGCATGTATCTCATTCAGATGTGCCTTTTGTTTTTGCAGACTATGACGTCTTTAGCTAATG
AATTGCCTATTGTTATGGAAAACAGTTAATATGCCATGTATGTACAGTTTTGTTTATATTGTATATTTAAAGATACTGCTAATAACCTAT
ATAAATTTAAGTGACTTGAGGCCTATAATACAATCTGCTACTTTACTAATTCATAAATTCAAAAAAAATTCTATGGCATAGGAACCAACT
GCCTTGCCTTCAAGACCTAGTAACTTTCTCTATAAATCTCGTGTTAACTGAAATTTTTTTTAAATATATTTTTTAGATTGGTAATATTTA
AACCAGCAAATACTTAAAGCTTTATTAAACATTTTAATCAGATAAGTGAGTAAAGCTTTTATTTGCCATTTGGATGCCTTCGTTCAAAGT
GATAGAGTGTTTTGCTGATAGTGCTGTAGCAGCAGTTGTAAAGTAGCCAAAAGCCACGTTGTTTATTTACTGGTTTGTGGCCTTTTACTG

>14331_14331_1_CCT5-SOS2_CCT5_chr5_10263426_ENST00000280326_SOS2_chr14_50625364_ENST00000216373_length(amino acids)=1224AA_BP=509
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEI
PEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRK
KQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTN
LTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLK
SINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLF
NKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASS
DLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPR
VPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLS

--------------------------------------------------------------
>14331_14331_2_CCT5-SOS2_CCT5_chr5_10263426_ENST00000280326_SOS2_chr14_50625364_ENST00000543680_length(transcript)=4099nt_BP=1918nt
AAAAAAAAAAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATT
CCTCCTTGGGACCCACTATCGAGAAACTATCAGTGGTAACGTTTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGA
TTTCCACTAAGTGTCTTCAAACCTCCCCCTCCCCGGCTTCCTGGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTG
GCGTGAAATTAGTCTCAGTAGAAACATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTG
CATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGAT
GAATATGGGCGCCCTTTCCTCATCATCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCA
GCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTA
ACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGAT
GAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCA
ATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAG
GACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTG
AATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAG
GACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATT
CTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATAC
GAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCA
AATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGG
ATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAA
ATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGA
TCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCC
CTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATG
GCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGC
ATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTG
CTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATC
AGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCAT
TTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTA
GAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCA
ATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTT
TTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAAT
TTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCA
GTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCA
GTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGAT
CACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACC
GAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAA
ATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCA
TCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAA
TCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCA
TTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACA
CCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTT
GCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCT
CTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGA
CAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCA
AGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCA
CTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCA
AGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCA
AGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCA

>14331_14331_2_CCT5-SOS2_CCT5_chr5_10263426_ENST00000280326_SOS2_chr14_50625364_ENST00000543680_length(amino acids)=1224AA_BP=509
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEI
PEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRK
KQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTN
LTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLK
SINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLF
NKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASS
DLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPR
VPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLS

--------------------------------------------------------------
>14331_14331_3_CCT5-SOS2_CCT5_chr5_10263426_ENST00000503026_SOS2_chr14_50625364_ENST00000216373_length(transcript)=4872nt_BP=1510nt
AAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTG
GGACCCACTATCGAGAAACTATCAGTGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGG
CTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAG
ATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTG
TTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAA
CACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAA
GTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTT
GAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCAC
CCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTG
GATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGT
GCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGA
GGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCT
GGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTT
ATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAAT
CGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTAT
GCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAA
GTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACT
TTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACT
GACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAA
CTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCC
TTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAAC
GGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTC
ATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGG
AGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAA
AAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAAT
AATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGG
AAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGT
GTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATC
AATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGAT
ATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATT
GAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGA
CATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACT
GAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTA
GATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGT
AGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGA
AATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGT
GCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCA
GAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACG
TGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTT
GCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTT
TCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCAGAAACTCCCCAATGACCTTAGCCATATGTAGTCATTGACACTGGAATG
GTATTTGTAAAGTTTTTTTTTTAATTTATTCAAAAAAAGACATAGTATTTTAGTACTTTTTACAAATAATGCTCTTACAAAAATGCTACT
GATCAAATAAGCTTTTAAGAATTGGAAAAATAAAAATACAAAAGTCCTTCACCATTATCCTCAGGTGATCAGTAGCATTGCCTTGTCTTG
GATCCTCAGTGCTGCCAAAAGGCCAGTATAAAGAATTTATATTTGCACTGTAAACTCTGCAAAAATATGGTTTAAAGTGACATGATTGCA
CTGAAAAGGGATAGTGCTTTTGTGAAATTTTTCAAATTTGAGTAATAGATGCCTTTTTAAGGCAGTGAATTTACACAAATATGGGAGGGG
TATATGGTGTTACTGATTTTTAAACCTCTTTGACCATCTTCTAGTTTTTACTTCTAGTTTTTACATCTAGGAGAATTGTGAATAACACCA
ACTGTTCTTAAACTCTTTAATGCCATGTCTTAAATGCCGGTATTTGCTGCTGAAGACAAAAATGAAAAGTAGGATGAAAATAATAGAATG
GCACTGTAAGTGTTTATTATTTTGTCAAAATGTAAACAAAGACTACATAACCCAATGATGGAGGGAAAAAGGGCATGTATCTCATTCAGA
TGTGCCTTTTGTTTTTGCAGACTATGACGTCTTTAGCTAATGAATTGCCTATTGTTATGGAAAACAGTTAATATGCCATGTATGTACAGT
TTTGTTTATATTGTATATTTAAAGATACTGCTAATAACCTATATAAATTTAAGTGACTTGAGGCCTATAATACAATCTGCTACTTTACTA
ATTCATAAATTCAAAAAAAATTCTATGGCATAGGAACCAACTGCCTTGCCTTCAAGACCTAGTAACTTTCTCTATAAATCTCGTGTTAAC
TGAAATTTTTTTTAAATATATTTTTTAGATTGGTAATATTTAAACCAGCAAATACTTAAAGCTTTATTAAACATTTTAATCAGATAAGTG
AGTAAAGCTTTTATTTGCCATTTGGATGCCTTCGTTCAAAGTGATAGAGTGTTTTGCTGATAGTGCTGTAGCAGCAGTTGTAAAGTAGCC
AAAAGCCACGTTGTTTATTTACTGGTTTGTGGCCTTTTACTGTGCTTTGTATCAGAGTTCTTAACAAGATTAATAAATCACCCCAGTCTT

>14331_14331_3_CCT5-SOS2_CCT5_chr5_10263426_ENST00000503026_SOS2_chr14_50625364_ENST00000216373_length(amino acids)=1193AA_BP=478
MNSSLGPTIEKLSVSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVV
LAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMER
RDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQ
IKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSR
AVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPI
QTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEY
VQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQF
ETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQV
FQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKK
GKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIR
PNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSF
FSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPV
PLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKT

--------------------------------------------------------------
>14331_14331_4_CCT5-SOS2_CCT5_chr5_10263426_ENST00000503026_SOS2_chr14_50625364_ENST00000543680_length(transcript)=3691nt_BP=1510nt
AAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTG
GGACCCACTATCGAGAAACTATCAGTGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGG
CTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAG
ATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTG
TTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAA
CACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAA
GTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTT
GAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCAC
CCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTG
GATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGT
GCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGA
GGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCT
GGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTT
ATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAAT
CGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTAT
GCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAA
GTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACT
TTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACT
GACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAA
CTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCC
TTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAAC
GGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTC
ATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGG
AGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAA
AAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAAT
AATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGG
AAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGT
GTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATC
AATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGAT
ATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATT
GAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGA
CATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACT
GAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTA
GATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGT
AGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGA
AATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGT
GCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCA
GAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACG
TGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTT
GCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTT
TCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCAGAAACTCCCCAATGACCTTAGCCATATGTAGTCATTGACACTGGAATG

>14331_14331_4_CCT5-SOS2_CCT5_chr5_10263426_ENST00000503026_SOS2_chr14_50625364_ENST00000543680_length(amino acids)=1193AA_BP=478
MNSSLGPTIEKLSVSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVV
LAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMER
RDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQ
IKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSR
AVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPI
QTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEY
VQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQF
ETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQV
FQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKK
GKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIR
PNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSF
FSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPV
PLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKT

--------------------------------------------------------------
>14331_14331_5_CCT5-SOS2_CCT5_chr5_10263426_ENST00000506600_SOS2_chr14_50625364_ENST00000216373_length(transcript)=4945nt_BP=1583nt
GTGCTCCCCGGAAAGGTCGAGAATCTCCGTCTCCCTGCGGTCTCCGGCCGCTCAGCCCGCTTACTGAGCTCGGGAGACGCCGGCGCCTAA
TCCTGGGCTCGGAATGTGGGGGCCAGCCAGGCTGGGCCGCCAGCGCCCTTCGGAGCTGGGTGGGGCCGCTCAGTCCGGTCGCCCGCGGGA
GCAAAGCGGGACCGCCTCCCCGCCCGGCTCCTCCAGCCTGACGGCCGCGTGGGACTGCGCTCCAGTGGGAGGGCGCCGGGGAGATGCTCT
GTCACCTGTCGGTTAAGGCGCTGCTGCTTAACCTTTCGCTGGTCCACCCGCAACGGCCCTTCCGTTTTCTTTGTCACTCGTAAAGTCTCA
TATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCA
ATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAG
CGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCA
CCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGA
AGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAA
AGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGA
AGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTG
TCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCT
GATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGAT
CTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAA
GATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGG
AGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGC
CGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGT
GAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCG
TTCATTTTGTAAACCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGC
AATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGT
ATTTCGGCATTGGGTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAG
AGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATAT
TACCTTTGAAAGTCCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAAT
AGAAATTGCACGTCAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGA
AGATAAAGAAATAAATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGC
AGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATT
GGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGA
CGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAAT
ATATTTAACAAATATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAG
GAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGA
AAACCTTAACCCCATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAA
ACAGCCACCTCGATTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGG
TACTTTACGAGGTCACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGT
GTCAGCACCAACCTCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAG
CTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAG
TGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGA
TGATCCTCCTGCTATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCT
GCATAGTCCACCTCCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTG
TCCATTTAATCTTCAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAG
CACTCCTCCTAGCACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCC
CCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTA
CAGACTGCCTTTGCTAGAAAATGCAGAAACTCCCCAATGACCTTAGCCATATGTAGTCATTGACACTGGAATGGTATTTGTAAAGTTTTT
TTTTTAATTTATTCAAAAAAAGACATAGTATTTTAGTACTTTTTACAAATAATGCTCTTACAAAAATGCTACTGATCAAATAAGCTTTTA
AGAATTGGAAAAATAAAAATACAAAAGTCCTTCACCATTATCCTCAGGTGATCAGTAGCATTGCCTTGTCTTGGATCCTCAGTGCTGCCA
AAAGGCCAGTATAAAGAATTTATATTTGCACTGTAAACTCTGCAAAAATATGGTTTAAAGTGACATGATTGCACTGAAAAGGGATAGTGC
TTTTGTGAAATTTTTCAAATTTGAGTAATAGATGCCTTTTTAAGGCAGTGAATTTACACAAATATGGGAGGGGTATATGGTGTTACTGAT
TTTTAAACCTCTTTGACCATCTTCTAGTTTTTACTTCTAGTTTTTACATCTAGGAGAATTGTGAATAACACCAACTGTTCTTAAACTCTT
TAATGCCATGTCTTAAATGCCGGTATTTGCTGCTGAAGACAAAAATGAAAAGTAGGATGAAAATAATAGAATGGCACTGTAAGTGTTTAT
TATTTTGTCAAAATGTAAACAAAGACTACATAACCCAATGATGGAGGGAAAAAGGGCATGTATCTCATTCAGATGTGCCTTTTGTTTTTG
CAGACTATGACGTCTTTAGCTAATGAATTGCCTATTGTTATGGAAAACAGTTAATATGCCATGTATGTACAGTTTTGTTTATATTGTATA
TTTAAAGATACTGCTAATAACCTATATAAATTTAAGTGACTTGAGGCCTATAATACAATCTGCTACTTTACTAATTCATAAATTCAAAAA
AAATTCTATGGCATAGGAACCAACTGCCTTGCCTTCAAGACCTAGTAACTTTCTCTATAAATCTCGTGTTAACTGAAATTTTTTTTAAAT
ATATTTTTTAGATTGGTAATATTTAAACCAGCAAATACTTAAAGCTTTATTAAACATTTTAATCAGATAAGTGAGTAAAGCTTTTATTTG
CCATTTGGATGCCTTCGTTCAAAGTGATAGAGTGTTTTGCTGATAGTGCTGTAGCAGCAGTTGTAAAGTAGCCAAAAGCCACGTTGTTTA

>14331_14331_5_CCT5-SOS2_CCT5_chr5_10263426_ENST00000506600_SOS2_chr14_50625364_ENST00000216373_length(amino acids)=1129AA_BP=414
MSLVKSHIMAAKAVANTMRTSLGPNVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGS
KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHK
LDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF
AGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQ
YAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEP
TDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQA
NGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWF
EKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPP
CVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLE
IEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVF
LDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPT
GAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNN

--------------------------------------------------------------
>14331_14331_6_CCT5-SOS2_CCT5_chr5_10263426_ENST00000506600_SOS2_chr14_50625364_ENST00000543680_length(transcript)=3764nt_BP=1583nt
GTGCTCCCCGGAAAGGTCGAGAATCTCCGTCTCCCTGCGGTCTCCGGCCGCTCAGCCCGCTTACTGAGCTCGGGAGACGCCGGCGCCTAA
TCCTGGGCTCGGAATGTGGGGGCCAGCCAGGCTGGGCCGCCAGCGCCCTTCGGAGCTGGGTGGGGCCGCTCAGTCCGGTCGCCCGCGGGA
GCAAAGCGGGACCGCCTCCCCGCCCGGCTCCTCCAGCCTGACGGCCGCGTGGGACTGCGCTCCAGTGGGAGGGCGCCGGGGAGATGCTCT
GTCACCTGTCGGTTAAGGCGCTGCTGCTTAACCTTTCGCTGGTCCACCCGCAACGGCCCTTCCGTTTTCTTTGTCACTCGTAAAGTCTCA
TATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCA
ATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAG
CGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCA
CCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGA
AGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAA
AGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGA
AGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTG
TCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCT
GATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGAT
CTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAA
GATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGG
AGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGC
CGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGT
GAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCG
TTCATTTTGTAAACCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGC
AATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGT
ATTTCGGCATTGGGTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAG
AGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATAT
TACCTTTGAAAGTCCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAAT
AGAAATTGCACGTCAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGA
AGATAAAGAAATAAATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGC
AGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATT
GGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGA
CGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAAT
ATATTTAACAAATATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAG
GAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGA
AAACCTTAACCCCATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAA
ACAGCCACCTCGATTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGG
TACTTTACGAGGTCACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGT
GTCAGCACCAACCTCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAG
CTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAG
TGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGA
TGATCCTCCTGCTATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCT
GCATAGTCCACCTCCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTG
TCCATTTAATCTTCAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAG
CACTCCTCCTAGCACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCC
CCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTA

>14331_14331_6_CCT5-SOS2_CCT5_chr5_10263426_ENST00000506600_SOS2_chr14_50625364_ENST00000543680_length(amino acids)=1129AA_BP=414
MSLVKSHIMAAKAVANTMRTSLGPNVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGS
KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHK
LDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF
AGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQ
YAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEP
TDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQA
NGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWF
EKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPP
CVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLE
IEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVF
LDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPT
GAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNN

--------------------------------------------------------------
>14331_14331_7_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515390_SOS2_chr14_50625364_ENST00000216373_length(transcript)=4820nt_BP=1458nt
ATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCC
GCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCCTCATCA
TCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGA
GAACATCACTTGGACCAAATGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAG
CCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAAC
CCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCC
TCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAAC
TGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTC
CATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGA
AATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTAC
TTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCA
GGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCA
TCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACG
ATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTA
GCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTG
AAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTT
TGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTGCTGAGCTTAC
TGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACC
TTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCATTTTTATGACT
TTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTG
CTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCAATTGAATGGC
ATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTTTTGGAGTCTG
ATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAATTTATTAAAAA
TGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTA
GAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTAT
ACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAA
AATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACCGAAGAAGGGA
ATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGT
ATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCATCTGAAAAAG
AGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAATCAACTTTTT
CCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCATTAGAAAGAG
AACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACACCATCTACTC
CACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGC
TTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTC
GAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGACAGCCTCCTC
CTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCAAGAGATCCTC
TTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCACTGGGGCATC
TTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCAAGGGTACCGC
GTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATC
TGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCAGAAACTCCCC
AATGACCTTAGCCATATGTAGTCATTGACACTGGAATGGTATTTGTAAAGTTTTTTTTTTAATTTATTCAAAAAAAGACATAGTATTTTA
GTACTTTTTACAAATAATGCTCTTACAAAAATGCTACTGATCAAATAAGCTTTTAAGAATTGGAAAAATAAAAATACAAAAGTCCTTCAC
CATTATCCTCAGGTGATCAGTAGCATTGCCTTGTCTTGGATCCTCAGTGCTGCCAAAAGGCCAGTATAAAGAATTTATATTTGCACTGTA
AACTCTGCAAAAATATGGTTTAAAGTGACATGATTGCACTGAAAAGGGATAGTGCTTTTGTGAAATTTTTCAAATTTGAGTAATAGATGC
CTTTTTAAGGCAGTGAATTTACACAAATATGGGAGGGGTATATGGTGTTACTGATTTTTAAACCTCTTTGACCATCTTCTAGTTTTTACT
TCTAGTTTTTACATCTAGGAGAATTGTGAATAACACCAACTGTTCTTAAACTCTTTAATGCCATGTCTTAAATGCCGGTATTTGCTGCTG
AAGACAAAAATGAAAAGTAGGATGAAAATAATAGAATGGCACTGTAAGTGTTTATTATTTTGTCAAAATGTAAACAAAGACTACATAACC
CAATGATGGAGGGAAAAAGGGCATGTATCTCATTCAGATGTGCCTTTTGTTTTTGCAGACTATGACGTCTTTAGCTAATGAATTGCCTAT
TGTTATGGAAAACAGTTAATATGCCATGTATGTACAGTTTTGTTTATATTGTATATTTAAAGATACTGCTAATAACCTATATAAATTTAA
GTGACTTGAGGCCTATAATACAATCTGCTACTTTACTAATTCATAAATTCAAAAAAAATTCTATGGCATAGGAACCAACTGCCTTGCCTT
CAAGACCTAGTAACTTTCTCTATAAATCTCGTGTTAACTGAAATTTTTTTTAAATATATTTTTTAGATTGGTAATATTTAAACCAGCAAA
TACTTAAAGCTTTATTAAACATTTTAATCAGATAAGTGAGTAAAGCTTTTATTTGCCATTTGGATGCCTTCGTTCAAAGTGATAGAGTGT
TTTGCTGATAGTGCTGTAGCAGCAGTTGTAAAGTAGCCAAAAGCCACGTTGTTTATTTACTGGTTTGTGGCCTTTTACTGTGCTTTGTAT

>14331_14331_7_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515390_SOS2_chr14_50625364_ENST00000216373_length(amino acids)=1169AA_BP=454
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNVLAGALLEEAEQLLDRGIHPIRIAD
GYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLI
KGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLL
QNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDA
LCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLH
KGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFE
RDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDL
YRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYR
LDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQ
NQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREP
CKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRK
KFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLH

--------------------------------------------------------------
>14331_14331_8_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515390_SOS2_chr14_50625364_ENST00000543680_length(transcript)=3639nt_BP=1458nt
ATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCC
GCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCCTCATCA
TCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGA
GAACATCACTTGGACCAAATGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAG
CCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAAC
CCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCC
TCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAAC
TGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTC
CATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGA
AATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTAC
TTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCA
GGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCA
TCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACG
ATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTA
GCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTG
AAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTT
TGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTGCTGAGCTTAC
TGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACC
TTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCATTTTTATGACT
TTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATGAAAAAATGGGTAGAGTCAATTG
CTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCAATTGAATGGC
ATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGTCAGCTGACACTTTTGGAGTCTG
ATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAATTTATTAAAAA
TGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAAGAACGGGTGGCAGTACTAAGTA
GAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCAGTGTCAGTAT
ACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAATTAAGTCAAGATCACTTTAAAA
AATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACCGAAGAAGGGA
ATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAAATTACTGGAGAAATTCAGCAGT
ATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCATCTGAAAAAG
AGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGATTTCCTAGGAAATCAACTTTTT
CCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCATTAGAAAGAG
AACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACCTCTCCAAATACACCATCTACTC
CACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTTGCTCCAGTGC
TTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTC
GAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGACAGCCTCCTC
CTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCTCCGCCACCACCAAGAGATCCTC
TTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCACTGGGGCATC
TTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGCACACCCTCTCCAAGGGTACCGC
GTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCAAGCCCTCATC
TGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTGCTAGAAAATGCAGAAACTCCCC

>14331_14331_8_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515390_SOS2_chr14_50625364_ENST00000543680_length(amino acids)=1169AA_BP=454
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNVLAGALLEEAEQLLDRGIHPIRIAD
GYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLI
KGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLL
QNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDA
LCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLH
KGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFE
RDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIARQLTLLESDL
YRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYR
LDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQ
NQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREP
CKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRK
KFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLH

--------------------------------------------------------------
>14331_14331_9_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515676_SOS2_chr14_50625364_ENST00000216373_length(transcript)=5112nt_BP=1750nt
ATGTGCTCCCCGGAAAGGTCGAGAATCTCCGTCTCCCTGCGGTCTCCGGCCGCTCAGCCCGCTTACTGAGCTCGGGAGACGCCGGCGCCT
AATCCTGGGCTCGGAATGTGGGGGCCAGCCAGGCTGGGCCGCCAGCGCCCTTCGGAGCTGGGTGGGGCCGCTCAGTCCGGTCGCCCGCGG
GAGCAAAGCGGGACCGCCTCCCCGCCCGGCTCCTCCAGCCTGACGGCCGCGTGGGACTGCGCTCCAGTGGGAGGGCGCCGGGGAGATGCT
CTGTCACCTGTCGGTTAAGGCGCTGCTGCTTAACCTTTCGCTGGTCCACCCGCAACGGCCCTTCCGTTTTCTTTGTCACTCGTAAAGTCT
CATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGA
GATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAG
TCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGA
GGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTT
GTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCT
GAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGC
GGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCG
AAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCC
CTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTT
GATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCA
ACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACA
ACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAG
GAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAG
ATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAG
GTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAAC
CCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAA
CCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGC
GAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGG
GTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATG
AAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGT
CCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGT
CAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATA
AATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAA
GAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGT
GCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAA
TTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAAT
ATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAA
ATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCC
ATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGA
TTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGT
CACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACC
TCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGC
AATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTG
ATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCT
ATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCT
CCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTT
CAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGC
ACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCA
AGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTG
CTAGAAAATGCAGAAACTCCCCAATGACCTTAGCCATATGTAGTCATTGACACTGGAATGGTATTTGTAAAGTTTTTTTTTTAATTTATT
CAAAAAAAGACATAGTATTTTAGTACTTTTTACAAATAATGCTCTTACAAAAATGCTACTGATCAAATAAGCTTTTAAGAATTGGAAAAA
TAAAAATACAAAAGTCCTTCACCATTATCCTCAGGTGATCAGTAGCATTGCCTTGTCTTGGATCCTCAGTGCTGCCAAAAGGCCAGTATA
AAGAATTTATATTTGCACTGTAAACTCTGCAAAAATATGGTTTAAAGTGACATGATTGCACTGAAAAGGGATAGTGCTTTTGTGAAATTT
TTCAAATTTGAGTAATAGATGCCTTTTTAAGGCAGTGAATTTACACAAATATGGGAGGGGTATATGGTGTTACTGATTTTTAAACCTCTT
TGACCATCTTCTAGTTTTTACTTCTAGTTTTTACATCTAGGAGAATTGTGAATAACACCAACTGTTCTTAAACTCTTTAATGCCATGTCT
TAAATGCCGGTATTTGCTGCTGAAGACAAAAATGAAAAGTAGGATGAAAATAATAGAATGGCACTGTAAGTGTTTATTATTTTGTCAAAA
TGTAAACAAAGACTACATAACCCAATGATGGAGGGAAAAAGGGCATGTATCTCATTCAGATGTGCCTTTTGTTTTTGCAGACTATGACGT
CTTTAGCTAATGAATTGCCTATTGTTATGGAAAACAGTTAATATGCCATGTATGTACAGTTTTGTTTATATTGTATATTTAAAGATACTG
CTAATAACCTATATAAATTTAAGTGACTTGAGGCCTATAATACAATCTGCTACTTTACTAATTCATAAATTCAAAAAAAATTCTATGGCA
TAGGAACCAACTGCCTTGCCTTCAAGACCTAGTAACTTTCTCTATAAATCTCGTGTTAACTGAAATTTTTTTTAAATATATTTTTTAGAT
TGGTAATATTTAAACCAGCAAATACTTAAAGCTTTATTAAACATTTTAATCAGATAAGTGAGTAAAGCTTTTATTTGCCATTTGGATGCC
TTCGTTCAAAGTGATAGAGTGTTTTGCTGATAGTGCTGTAGCAGCAGTTGTAAAGTAGCCAAAAGCCACGTTGTTTATTTACTGGTTTGT

>14331_14331_9_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515676_SOS2_chr14_50625364_ENST00000216373_length(amino acids)=1184AA_BP=469
MSLVKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIK
VEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGG
NKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
QVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRIL
NVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLH
PIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNG
VLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSK
RRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGST
SGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHK
LSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFI
NCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPP

--------------------------------------------------------------
>14331_14331_10_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515676_SOS2_chr14_50625364_ENST00000543680_length(transcript)=3931nt_BP=1750nt
ATGTGCTCCCCGGAAAGGTCGAGAATCTCCGTCTCCCTGCGGTCTCCGGCCGCTCAGCCCGCTTACTGAGCTCGGGAGACGCCGGCGCCT
AATCCTGGGCTCGGAATGTGGGGGCCAGCCAGGCTGGGCCGCCAGCGCCCTTCGGAGCTGGGTGGGGCCGCTCAGTCCGGTCGCCCGCGG
GAGCAAAGCGGGACCGCCTCCCCGCCCGGCTCCTCCAGCCTGACGGCCGCGTGGGACTGCGCTCCAGTGGGAGGGCGCCGGGGAGATGCT
CTGTCACCTGTCGGTTAAGGCGCTGCTGCTTAACCTTTCGCTGGTCCACCCGCAACGGCCCTTCCGTTTTCTTTGTCACTCGTAAAGTCT
CATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGA
GATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAG
TCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGA
GGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTT
GTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCT
GAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGC
GGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCG
AAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCC
CTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTT
GATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCA
ACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACA
ACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAG
GAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAG
ATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAG
GTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAAC
CCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATCCCAATTTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAA
CCACAGGAATTGCTGAGCTTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCAATAGAGAAAGGC
GAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTCCAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGG
GTTGAACATCATTTTTATGACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGAGGGAAAGCTATG
AAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAAGCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGT
CCACCTCCACCAATTGAATGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATAGAAATTGCACGT
CAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCTGAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATA
AATTCTCCAAATTTATTAAAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCAGAAAATTTTGAA
GAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTTCAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGT
GCAGTAAATTCAGTGTCAGTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGACGAAGCTGTGGAA
TTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATCAATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAAT
ATTCTGAAGACCGAAGAAGGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGGAAAGTAGCTGAA
ATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGGATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCC
ATGGGAAGTGCATCTGAAAAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAACAGCCACCTCGA
TTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCTAACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGT
CACCCAACACCATTAGAAAGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTGTCAGCACCAACC
TCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTTAGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGC
AATAGCATCTTTGCTCCAGTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGTGAAGAGCCCCTG
ATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCAAATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCT
ATTCCACCGAGACAGCCTCCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTGCATAGTCCACCT
CCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCCCTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTT
CAGCCACCTCCACTGGGGCATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGCACTCCTCCTAGC
ACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGTCAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCA
AGGCAGAATTCAAGCCCTCATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTACAGACTGCCTTTG

>14331_14331_10_CCT5-SOS2_CCT5_chr5_10263426_ENST00000515676_SOS2_chr14_50625364_ENST00000543680_length(amino acids)=1184AA_BP=469
MSLVKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIK
VEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGG
NKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
QVKEMNPALGIDCLHKGTNDPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLAIEKGEQPISADLKRFRKEYVQPVQLRIL
NVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLH
PIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENFEERVAVLSRIIEILQVFQDLNNFNG
VLEIVSAVNSVSVYRLDHTFEALQERKRKILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSK
RRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGST
SGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHK
LSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFI
NCPFNLQPPPLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPP

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Fusion Gene PPI Analysis for CCT5-SOS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCT5-SOS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCT5-SOS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource