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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD63-C12orf10 (FusionGDB2 ID:14579)

Fusion Gene Summary for CD63-C12orf10

check button Fusion gene summary
Fusion gene informationFusion gene name: CD63-C12orf10
Fusion gene ID: 14579
HgeneTgene
Gene symbol

CD63

C12orf10

Gene ID

967

60314

Gene nameCD63 moleculeMYG1 exonuclease
SynonymsLAMP-3|ME491|MLA1|OMA81H|TSPAN30C12orf10|Gamm1|MST024|MSTP024|MYG
Cytomap

12q13.2

12q13.13

Type of geneprotein-codingprotein-coding
DescriptionCD63 antigenCD63 antigen (melanoma 1 antigen)granulophysinlysosomal-associated membrane protein 3lysosome-associated membrane glycoprotein 3melanoma-associated antigen ME491melanoma-associated antigen MLA1ocular melanoma-associated antigentetraspaUPF0160 protein MYG1, mitochondrialmelanocyte proliferating gene 1melanocyte related
Modification date2020032720200320
UniProtAcc

P08962

.
Ensembl transtripts involved in fusion geneENST00000257857, ENST00000420846, 
ENST00000546939, ENST00000548160, 
ENST00000548898, ENST00000549117, 
ENST00000550776, ENST00000552067, 
ENST00000552692, ENST00000552754, 
ENST00000549488, ENST00000267103, 
ENST00000548632, 
Fusion gene scores* DoF score23 X 19 X 9=39338 X 12 X 5=480
# samples 2312
** MAII scorelog2(23/3933*10)=-4.09592441999854
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/480*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CD63 [Title/Abstract] AND C12orf10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD63(56120484)-C12orf10(53693934), # samples:2
Anticipated loss of major functional domain due to fusion event.CD63-C12orf10 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CD63-C12orf10 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD63

GO:0034613

cellular protein localization

15647390

HgeneCD63

GO:1901379

regulation of potassium ion transmembrane transport

15647390


check buttonFusion gene breakpoints across CD63 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C12orf10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D3-A3C1-06ACD63chr12

56120484

-C12orf10chr12

53693934

+


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Fusion Gene ORF analysis for CD63-C12orf10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000257857ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000420846ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000546939ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000548160ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000548898ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000549117ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000550776ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000552067ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000552692ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
5CDS-5UTRENST00000552754ENST00000549488CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000546939ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000546939ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000549117ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000549117ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000550776ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000550776ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000552067ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
Frame-shiftENST00000552067ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000257857ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000257857ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000420846ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000420846ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000548160ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000548160ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000548898ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000548898ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000552692ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000552692ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000552754ENST00000267103CD63chr12

56120484

-C12orf10chr12

53693934

+
In-frameENST00000552754ENST00000548632CD63chr12

56120484

-C12orf10chr12

53693934

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000548898CD63chr1256120484-ENST00000267103C12orf10chr1253693934+1122198391112357
ENST00000548898CD63chr1256120484-ENST00000548632C12orf10chr1253693934+98219839959306
ENST00000420846CD63chr1256120484-ENST00000267103C12orf10chr1253693934+15356111611525454
ENST00000420846CD63chr1256120484-ENST00000548632C12orf10chr1253693934+13956111611372403
ENST00000548160CD63chr1256120484-ENST00000267103C12orf10chr1253693934+1190266831180365
ENST00000548160CD63chr1256120484-ENST00000548632C12orf10chr1253693934+1050266831027314
ENST00000552692CD63chr1256120484-ENST00000267103C12orf10chr1253693934+14915671411481446
ENST00000552692CD63chr1256120484-ENST00000548632C12orf10chr1253693934+13515671411328395
ENST00000257857CD63chr1256120484-ENST00000267103C12orf10chr1253693934+16297052551619454
ENST00000257857CD63chr1256120484-ENST00000548632C12orf10chr1253693934+14897052551466403
ENST00000552754CD63chr1256120484-ENST00000267103C12orf10chr1253693934+128936581279423
ENST00000552754CD63chr1256120484-ENST00000548632C12orf10chr1253693934+114936581126372

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000548898ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0069899170.9930101
ENST00000548898ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0129973160.9870027
ENST00000420846ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0025968150.9974032
ENST00000420846ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0018818370.99811816
ENST00000548160ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0058766350.9941234
ENST00000548160ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0108891930.98911077
ENST00000552692ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0020929240.99790704
ENST00000552692ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0015095160.99849045
ENST00000257857ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0025460230.997454
ENST00000257857ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0017916130.9982084
ENST00000552754ENST00000267103CD63chr1256120484-C12orf10chr1253693934+0.0018065440.99819344
ENST00000552754ENST00000548632CD63chr1256120484-C12orf10chr1253693934+0.0019323330.9980677

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Fusion Genomic Features for CD63-C12orf10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CD63chr1256120483-C12orf10chr1253693933+1.92E-050.9999808
CD63chr1256120483-C12orf10chr1253693933+1.92E-050.9999808

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CD63-C12orf10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56120484/chr12:53693934)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CD63

P08962

.
FUNCTION: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. {ECO:0000269|PubMed:16917503, ECO:0000269|PubMed:21803846, ECO:0000269|PubMed:21962903, ECO:0000269|PubMed:23632027, ECO:0000269|PubMed:24635319}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-582_11142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-5833_51142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-5873_81142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-472_1160157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-4733_5160157.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-582_11142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-5833_51142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-5873_81142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-472_1160157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-4733_5160157.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-472_11142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-4733_51142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-4773_81142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-472_11119216.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-4733_51119216.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-4773_81119216.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-5812_32142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-5852_72142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-5882_102142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-4712_3260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-5812_32142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-5852_72142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-5882_102142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-4712_3260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-4712_32142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-4752_72142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-4782_102142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-4712_32119216.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-4752_72119216.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-4782_102119216.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-58234_238142239.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-47234_23860157.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-58234_238142239.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-47234_23860157.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-47234_238142239.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-47234_238119216.0MotifLysosomal targeting motif
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-58103_203142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-58225_238142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-47103_20360157.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-47225_23860157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-4773_8160157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-58103_203142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-58225_238142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-47103_20360157.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-47225_23860157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-4773_8160157.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-47103_203142239.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-47225_238142239.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-47103_203119216.0Topological domainExtracellular
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-47225_238119216.0Topological domainCytoplasmic
HgeneCD63chr12:56120484chr12:53693934ENST00000257857-58204_224142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-47204_22460157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-4752_7260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000546939-4782_10260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000549117-58204_224142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-47204_22460157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-4752_7260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000550776-4782_10260157.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552692-47204_224142239.0TransmembraneHelical
HgeneCD63chr12:56120484chr12:53693934ENST00000552754-47204_224119216.0TransmembraneHelical


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Fusion Gene Sequence for CD63-C12orf10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14579_14579_1_CD63-C12orf10_CD63_chr12_56120484_ENST00000257857_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1629nt_BP=705nt
CGGGGGTGGGCGCCTTCTTCCGGGTAGGGGCCACGTGGCCCTGGCCGGGCGGGGGGCTCGGCCCACCCCGCGCCGGGCCCAGTGACTCAG
GCCGCAGCTGTTACCGCGTCACATGAGGGAGGCCGGCGGCCACTCGGCGGGGGAGGGGACCGTGGCTGGAGCCCGGGGCGGGGCCGCGCG
GCAGGCGGGGCGGGAGCCGGGGGGCGCAGCTAGAGAGCCCCGGAGCCGCGGCGGGAGAGGAACGCGCAGCCAGCCTTGGGAAGCCCAGGC
CCGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGA
CTGATTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATAATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATC
ATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCC
ATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAAC
AACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTG
CGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCAT
CACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTG
CACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGATGTATGAGAAC
TTTGTGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCAGAGGGGGAGCCTCGATATGCACTGACCACTACCCTGAGTGCA
CGAGTTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACTGAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAG
TTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGAC
CCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTG
GCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTG
CCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGC
TTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCTCATACCTCCCACAAATCTCCTAG

>14579_14579_1_CD63-C12orf10_CD63_chr12_56120484_ENST00000257857_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=454AA_BP=150
MGSPGPAAMAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCL
MITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRR
HRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALT
TTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESG
LSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATLAQRSYL

--------------------------------------------------------------
>14579_14579_2_CD63-C12orf10_CD63_chr12_56120484_ENST00000257857_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=1489nt_BP=705nt
CGGGGGTGGGCGCCTTCTTCCGGGTAGGGGCCACGTGGCCCTGGCCGGGCGGGGGGCTCGGCCCACCCCGCGCCGGGCCCAGTGACTCAG
GCCGCAGCTGTTACCGCGTCACATGAGGGAGGCCGGCGGCCACTCGGCGGGGGAGGGGACCGTGGCTGGAGCCCGGGGCGGGGCCGCGCG
GCAGGCGGGGCGGGAGCCGGGGGGCGCAGCTAGAGAGCCCCGGAGCCGCGGCGGGAGAGGAACGCGCAGCCAGCCTTGGGAAGCCCAGGC
CCGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGA
CTGATTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATAATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATC
ATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCC
ATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAAC
AACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTG
CGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCAT
CACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTG
CACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGGCAGGGTTCAAG
CGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAG
GCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCAC
CTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAG
GAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCT
GGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAG

>14579_14579_2_CD63-C12orf10_CD63_chr12_56120484_ENST00000257857_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=403AA_BP=150
MGSPGPAAMAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCL
MITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRR
HRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPAR
ALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQ

--------------------------------------------------------------
>14579_14579_3_CD63-C12orf10_CD63_chr12_56120484_ENST00000420846_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1535nt_BP=611nt
CAGCTGTTACCGCGTCACATGAGGGAGGCCGGCGGCCACTCGGCGGGGGAGGGGACCGTGGCTGGAGCCCGGGGCGGGGCCGCGCGGCAG
GCGGGGCGGGAGCCGGGGGGCGCAGCTAGAGAGCCCCGGAGCCGCGGCGGGAGAGGAACGCGCAGCCAGCCTTGGGAAGCCCAGGCCCGG
CAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGACTGA
TTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATAATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATCATCG
CAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCCATCT
TTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACT
TCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGA
CCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCATCACC
AGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACT
TCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGATGTATGAGAACTTTG
TGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCAGAGGGGGAGCCTCGATATGCACTGACCACTACCCTGAGTGCACGAG
TTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACTGAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTC
TGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAA
GTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCA
TCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCC
TGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCA
CTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCTCATACCTCCCACAAATCTCCTAGTCTA

>14579_14579_3_CD63-C12orf10_CD63_chr12_56120484_ENST00000420846_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=454AA_BP=150
MGSPGPAAMAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCL
MITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRR
HRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALT
TTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESG
LSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATLAQRSYL

--------------------------------------------------------------
>14579_14579_4_CD63-C12orf10_CD63_chr12_56120484_ENST00000420846_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=1395nt_BP=611nt
CAGCTGTTACCGCGTCACATGAGGGAGGCCGGCGGCCACTCGGCGGGGGAGGGGACCGTGGCTGGAGCCCGGGGCGGGGCCGCGCGGCAG
GCGGGGCGGGAGCCGGGGGGCGCAGCTAGAGAGCCCCGGAGCCGCGGCGGGAGAGGAACGCGCAGCCAGCCTTGGGAAGCCCAGGCCCGG
CAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGACTGA
TTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATAATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATCATCG
CAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCCATCT
TTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACT
TCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGA
CCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCATCACC
AGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACT
TCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGGCAGGGTTCAAGCGTG
CAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCC
TTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGG
AATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGC
CCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCT
GCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCT

>14579_14579_4_CD63-C12orf10_CD63_chr12_56120484_ENST00000420846_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=403AA_BP=150
MGSPGPAAMAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCL
MITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRR
HRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPAR
ALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQ

--------------------------------------------------------------
>14579_14579_5_CD63-C12orf10_CD63_chr12_56120484_ENST00000548160_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1190nt_BP=266nt
GAAGACCTTTGTGAGTGTCCAGGGACCGGCTGTGCCAAAACGGGCCCCTGTAATGCATAGACTCCAAACTTGACTTCTGTCCTTTGCTCC
TGCAGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAG
AGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATG
CAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACC
GATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGAC
TCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGA
TGTATGAGAACTTTGTGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCAGAGGGGGAGCCTCGATATGCACTGACCACTA
CCCTGAGTGCACGAGTTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACTGAGGCAGGGTTCAAGCGTGCAATGGATCTGG
TTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGAT
TCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGT
CCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCC
AAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCC
ATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCTCATACCTCCCAC

>14579_14579_5_CD63-C12orf10_CD63_chr12_56120484_ENST00000548160_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=365AA_BP=61
MLLQFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPR
RHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYAL
TTTLSARVARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLES
GLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARATLAQRSY

--------------------------------------------------------------
>14579_14579_6_CD63-C12orf10_CD63_chr12_56120484_ENST00000548160_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=1050nt_BP=266nt
GAAGACCTTTGTGAGTGTCCAGGGACCGGCTGTGCCAAAACGGGCCCCTGTAATGCATAGACTCCAAACTTGACTTCTGTCCTTTGCTCC
TGCAGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGGTGATGTCAG
AGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGGCAGATGATG
CAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTCGGAGACACC
GATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCAGTGCGGGAC
TCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCTATGACAAGG
CAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCT
TGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGC
ATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGT
GTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCA
GTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCA

>14579_14579_6_CD63-C12orf10_CD63_chr12_56120484_ENST00000548160_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=314AA_BP=61
MLLQFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPR
RHRYDHHQRSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPA
RALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALD

--------------------------------------------------------------
>14579_14579_7_CD63-C12orf10_CD63_chr12_56120484_ENST00000548898_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1122nt_BP=198nt
AGAGCAGCTTGGTTCGGGCTCAGGAAGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTG
TTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTG
GACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGC
GAGTACGACCCTCGGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAG
ACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATG
GTGGGCACCCTCTATGACAAGATGTATGAGAACTTTGTGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCAGAGGGGGAG
CCTCGATATGCACTGACCACTACCCTGAGTGCACGAGTTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACTGAGGCAGGG
TTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTG
GAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTC
TACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTG
CCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGG
ATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTG

>14579_14579_7_CD63-C12orf10_CD63_chr12_56120484_ENST00000548898_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=357AA_BP=53
MSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQ
RSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARV
ARLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAI

--------------------------------------------------------------
>14579_14579_8_CD63-C12orf10_CD63_chr12_56120484_ENST00000548898_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=982nt_BP=198nt
AGAGCAGCTTGGTTCGGGCTCAGGAAGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTG
TTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTG
GACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGC
GAGTACGACCCTCGGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAG
ACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATG
GTGGGCACCCTCTATGACAAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACAC
AGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAA
GGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAG
GCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGG
GACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGT

>14579_14579_8_CD63-C12orf10_CD63_chr12_56120484_ENST00000548898_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=306AA_BP=53
MSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQ
RSFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEAL
AQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGC

--------------------------------------------------------------
>14579_14579_9_CD63-C12orf10_CD63_chr12_56120484_ENST00000552692_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1491nt_BP=567nt
GCGGGTTTCCGGGTGGGAGGGGCCGGGAATCGGGGCCGTGAAGGGAAGCCCTCGAGGGCCGGCCGGGAGCCCGGAAACCGAGGTCCCCCT
TCGGCCAGTTTTAATCCCCCCGCCCTCCCCTCTGCCCCAGGCCCGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTG
CTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGACTGATTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATA
ATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATCATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGC
GGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCT
GGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCT
TCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGAC
GTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAG
CCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAG
GACAGCATGGTGGGCACCCTCTATGACAAGATGTATGAGAACTTTGTGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCA
GAGGGGGAGCCTCGATATGCACTGACCACTACCCTGAGTGCACGAGTTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACT
GAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGG
GCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAG
GAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATA
CAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAG
GTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGT

>14579_14579_9_CD63-C12orf10_CD63_chr12_56120484_ENST00000552692_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=446AA_BP=142
MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFL
SLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQR
SFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVA
RLNPTWNHPDQDTEAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIF

--------------------------------------------------------------
>14579_14579_10_CD63-C12orf10_CD63_chr12_56120484_ENST00000552692_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=1351nt_BP=567nt
GCGGGTTTCCGGGTGGGAGGGGCCGGGAATCGGGGCCGTGAAGGGAAGCCCTCGAGGGCCGGCCGGGAGCCCGGAAACCGAGGTCCCCCT
TCGGCCAGTTTTAATCCCCCCGCCCTCCCCTCTGCCCCAGGCCCGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTG
CTCTACGTCCTCCTGCTGGCCTTTTGCGCCTGTGCAGTGGGACTGATTGCCGTGGGTGTCGGGGCACAGCTTGTCCTGAGTCAGACCATA
ATCCAGGGGGCTACCCCTGGCTCTCTGTTGCCAGTGGTCATCATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGC
GGGGCCTGCAAGGAGAACTATTGTCTTATGATCACGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCT
GGCTATGTGTTTAGAGATAAGGTGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCT
TCGATCCTGGACAGGATGCAGGCAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGAC
GTGGGGGGCGAGTACGACCCTCGGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAG
CCGTGGCAGACCAAGCTGAGCAGTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAG
GACAGCATGGTGGGCACCCTCTATGACAAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTC
TACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAA
CTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTAC
ACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGG
GGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACC
CGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCTCATACCTCCCACAAATCTCCTAGTCTAATAAAACCTTCCATCTC

>14579_14579_10_CD63-C12orf10_CD63_chr12_56120484_ENST00000552692_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=395AA_BP=142
MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFL
SLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQR
SFTETMSSLSPGKPWQTKLSSAGLIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALA
QRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCI

--------------------------------------------------------------
>14579_14579_11_CD63-C12orf10_CD63_chr12_56120484_ENST00000552754_C12orf10_chr12_53693934_ENST00000267103_length(transcript)=1289nt_BP=365nt
CGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGGGGCTACCCCTGGCT
CTCTGTTGCCAGTGGTCATCATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATT
GTCTTATGATCACGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGG
TGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGG
CAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTC
GGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCA
GTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCT
ATGACAAGATGTATGAGAACTTTGTGGAGGAGGTGGATGCTGTGGACAATGGGATCTCCCAGTGGGCAGAGGGGGAGCCTCGATATGCAC
TGACCACTACCCTGAGTGCACGAGTTGCTCGACTTAATCCTACCTGGAACCACCCCGACCAAGACACTGAGGCAGGGTTCAAGCGTGCAA
TGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAGCCCGGGCCTTGGTGGAAGAGGCCCTTG
CCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCTGGAAGGAGCATCTCTACCACCTGGAAT
CTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGCGAATACAGTGTGTGCCCAAGGAGCCCC
ACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGGACCAGGTCAGTGGGATCCCTGGCTGCA
TCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGGCCCGTGCCACCTTGGCCCAGCGCTCAT

>14579_14579_11_CD63-C12orf10_CD63_chr12_56120484_ENST00000552754_C12orf10_chr12_53693934_ENST00000267103_length(amino acids)=423AA_BP=119
MAVEGGMKCVKFLLYVLLLAFCGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMS
EFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAG
LIYLHFGHKLLAQLLGTSEEDSMVGTLYDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVARLNPTWNHPDQDTEAGFKRAMDL
VQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKEHLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSF

--------------------------------------------------------------
>14579_14579_12_CD63-C12orf10_CD63_chr12_56120484_ENST00000552754_C12orf10_chr12_53693934_ENST00000548632_length(transcript)=1149nt_BP=365nt
CGGCAGCCATGGCGGTGGAAGGAGGAATGAAATGTGTGAAGTTCTTGCTCTACGTCCTCCTGCTGGCCTTTTGCGGGGCTACCCCTGGCT
CTCTGTTGCCAGTGGTCATCATCGCAGTGGGTGTCTTCCTCTTCCTGGTGGCTTTTGTGGGCTGCTGCGGGGCCTGCAAGGAGAACTATT
GTCTTATGATCACGTTTGCCATCTTTCTGTCTCTTATCATGTTGGTGGAGGTGGCCGCAGCCATTGCTGGCTATGTGTTTAGAGATAAGG
TGATGTCAGAGTTTAATAACAACTTCCGGCAGCAGATGGAGAATTACCCGAAAAACAACCACACTGCTTCGATCCTGGACAGGATGCAGG
CAGATGATGCAGAGATTGTGCGGACCCGGGATCCCGAAAAACTCGCTTCCTGTGACATCGTGGTGGACGTGGGGGGCGAGTACGACCCTC
GGAGACACCGATATGACCATCACCAGAGGTCTTTCACAGAGACCATGAGCTCCCTGTCCCCTGGGAAGCCGTGGCAGACCAAGCTGAGCA
GTGCGGGACTCATCTATCTGCACTTCGGGCACAAGCTGCTGGCCCAGTTGCTGGGCACTAGTGAAGAGGACAGCATGGTGGGCACCCTCT
ATGACAAGGCAGGGTTCAAGCGTGCAATGGATCTGGTTCAAGAGGAGTTTCTGCAGAGATTAGATTTCTACCAACACAGCTGGCTGCCAG
CCCGGGCCTTGGTGGAAGAGGCCCTTGCCCAGCGATTCCAGGTGGACCCAAGTGGAGAGATTGTGGAACTGGCGAAAGGTGCATGTCCCT
GGAAGGAGCATCTCTACCACCTGGAATCTGGGCTGTCCCCTCCAGTGGCCATCTTCTTTGTTATCTACACTGACCAGGCTGGACAGTGGC
GAATACAGTGTGTGCCCAAGGAGCCCCACTCATTCCAAAGCCGGCTGCCCCTGCCAGAGCCATGGCGGGGTCTTCGGGACGAGGCCCTGG
ACCAGGTCAGTGGGATCCCTGGCTGCATCTTCGTCCATGCAAGCGGCTTCACTGGCGGTCACCACACCCGAGAGGGTGCCTTGAGCATGG

>14579_14579_12_CD63-C12orf10_CD63_chr12_56120484_ENST00000552754_C12orf10_chr12_53693934_ENST00000548632_length(amino acids)=372AA_BP=119
MAVEGGMKCVKFLLYVLLLAFCGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMS
EFNNNFRQQMENYPKNNHTASILDRMQADDAEIVRTRDPEKLASCDIVVDVGGEYDPRRHRYDHHQRSFTETMSSLSPGKPWQTKLSSAG
LIYLHFGHKLLAQLLGTSEEDSMVGTLYDKAGFKRAMDLVQEEFLQRLDFYQHSWLPARALVEEALAQRFQVDPSGEIVELAKGACPWKE
HLYHLESGLSPPVAIFFVIYTDQAGQWRIQCVPKEPHSFQSRLPLPEPWRGLRDEALDQVSGIPGCIFVHASGFTGGHHTREGALSMARA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CD63-C12orf10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD63-C12orf10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CD63-C12orf10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource