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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD74-APOBR (FusionGDB2 ID:14615)

Fusion Gene Summary for CD74-APOBR

check button Fusion gene summary
Fusion gene informationFusion gene name: CD74-APOBR
Fusion gene ID: 14615
HgeneTgene
Gene symbol

CD74

APOBR

Gene ID

972

55911

Gene nameCD74 moleculeapolipoprotein B receptor
SynonymsDHLAG|HLADG|II|Ia-GAMMA|p33APOB100R|APOB48R
Cytomap

5q33.1

16p12.1

Type of geneprotein-codingprotein-coding
DescriptionHLA class II histocompatibility antigen gamma chainCD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)CD74 molecule, major histocompatibility complex, class II invariant chainHLA-DR antigens-associated apolipoprotein B receptorapoB-48Rapolipoprotein B-100 receptorapolipoprotein B-48 receptorapolipoprotein B100 receptorapolipoprotein B48 receptor
Modification date2020031320200313
UniProtAcc

P04233

.
Ensembl transtripts involved in fusion geneENST00000009530, ENST00000353334, 
ENST00000377795, ENST00000524315, 
ENST00000328423, ENST00000431282, 
ENST00000564831, 
Fusion gene scores* DoF score43 X 51 X 20=438601 X 1 X 1=1
# samples 591
** MAII scorelog2(59/43860*10)=-6.21604704731175
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: CD74 [Title/Abstract] AND APOBR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD74(149784647)-APOBR(28506595), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD74

GO:0001516

prostaglandin biosynthetic process

12782713

HgeneCD74

GO:0001934

positive regulation of protein phosphorylation

24942581

HgeneCD74

GO:0002792

negative regulation of peptide secretion

19849849

HgeneCD74

GO:0033674

positive regulation of kinase activity

24942581

HgeneCD74

GO:0043066

negative regulation of apoptotic process

12782713

HgeneCD74

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB signaling

24942581

HgeneCD74

GO:0043410

positive regulation of MAPK cascade

24942581

HgeneCD74

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

17045821

HgeneCD74

GO:0045657

positive regulation of monocyte differentiation

24942581

HgeneCD74

GO:0045893

positive regulation of transcription, DNA-templated

24942581

HgeneCD74

GO:0046598

positive regulation of viral entry into host cell

24942581

HgeneCD74

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

17045821

HgeneCD74

GO:0070374

positive regulation of ERK1 and ERK2 cascade

17045821|24942581


check buttonFusion gene breakpoints across CD74 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across APOBR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ADA620171CD74chr5

149784647

-APOBRchr16

28506595

+


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Fusion Gene ORF analysis for CD74-APOBR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000009530ENST00000328423CD74chr5

149784647

-APOBRchr16

28506595

+
In-frameENST00000009530ENST00000431282CD74chr5

149784647

-APOBRchr16

28506595

+
In-frameENST00000009530ENST00000564831CD74chr5

149784647

-APOBRchr16

28506595

+
In-frameENST00000353334ENST00000328423CD74chr5

149784647

-APOBRchr16

28506595

+
In-frameENST00000353334ENST00000431282CD74chr5

149784647

-APOBRchr16

28506595

+
In-frameENST00000353334ENST00000564831CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000377795ENST00000328423CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000377795ENST00000431282CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000377795ENST00000564831CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000524315ENST00000328423CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000524315ENST00000431282CD74chr5

149784647

-APOBRchr16

28506595

+
intron-3CDSENST00000524315ENST00000564831CD74chr5

149784647

-APOBRchr16

28506595

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000353334CD74chr5149784647-ENST00000564831APOBRchr1628506595+424371772437771017
ENST00000353334CD74chr5149784647-ENST00000431282APOBRchr1628506595+388871772437501008
ENST00000353334CD74chr5149784647-ENST00000328423APOBRchr1628506595+36947177243693990
ENST00000009530CD74chr5149784647-ENST00000564831APOBRchr1628506595+406553954635991017
ENST00000009530CD74chr5149784647-ENST00000431282APOBRchr1628506595+371053954635721008
ENST00000009530CD74chr5149784647-ENST00000328423APOBRchr1628506595+35165395463515989

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000353334ENST00000564831CD74chr5149784647-APOBRchr1628506595+0.0194256440.98057437
ENST00000353334ENST00000431282CD74chr5149784647-APOBRchr1628506595+0.0284726660.97152734
ENST00000353334ENST00000328423CD74chr5149784647-APOBRchr1628506595+0.0276452340.9723548
ENST00000009530ENST00000564831CD74chr5149784647-APOBRchr1628506595+0.0190357920.98096424
ENST00000009530ENST00000431282CD74chr5149784647-APOBRchr1628506595+0.0287627340.97123724
ENST00000009530ENST00000328423CD74chr5149784647-APOBRchr1628506595+0.0299384990.97006154

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Fusion Genomic Features for CD74-APOBR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CD74-APOBR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:149784647/chr16:28506595)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CD74

P04233

.
FUNCTION: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.; FUNCTION: [Class-II-associated invariant chain peptide]: Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome. {ECO:0000269|PubMed:1448172}.; FUNCTION: [Isoform p41]: Stabilizes the conformation of mature CTSL by binding to its active site and serving as a chaperone to help maintain a pool of mature enzyme in endocytic compartments and extracellular space of antigen-presenting cells (APCs). Has antiviral activity by stymieing the endosomal entry of Ebola virus and coronaviruses, including SARS-CoV-2 (PubMed:32855215). Disrupts cathepsin-mediated Ebola virus glycoprotein processing, which prevents viral fusion and entry. This antiviral activity is specific to p41 isoform (PubMed:32855215). {ECO:0000250|UniProtKB:P04441, ECO:0000269|PubMed:32855215}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD74chr5:149784647chr16:28506595ENST00000009530-591_46179297.0Topological domainCytoplasmic
HgeneCD74chr5:149784647chr16:28506595ENST00000353334-581_46179233.0Topological domainCytoplasmic
HgeneCD74chr5:149784647chr16:28506595ENST00000009530-5947_72179297.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCD74chr5:149784647chr16:28506595ENST00000353334-5847_72179233.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneAPOBRchr5:149784647chr16:28506595ENST0000032842305158_97001070.0Compositional biasNote=Glu-rich
TgeneAPOBRchr5:149784647chr16:28506595ENST0000043128205158_97001089.0Compositional biasNote=Glu-rich
TgeneAPOBRchr5:149784647chr16:28506595ENST0000056483104158_97001098.0Compositional biasNote=Glu-rich

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD74chr5:149784647chr16:28506595ENST00000009530-59210_271179297.0DomainThyroglobulin type-1
HgeneCD74chr5:149784647chr16:28506595ENST00000353334-58210_271179233.0DomainThyroglobulin type-1
HgeneCD74chr5:149784647chr16:28506595ENST00000377795-16210_2710280.6666666666667DomainThyroglobulin type-1
HgeneCD74chr5:149784647chr16:28506595ENST00000009530-5973_296179297.0Topological domainExtracellular
HgeneCD74chr5:149784647chr16:28506595ENST00000353334-5873_296179233.0Topological domainExtracellular
HgeneCD74chr5:149784647chr16:28506595ENST00000377795-161_460280.6666666666667Topological domainCytoplasmic
HgeneCD74chr5:149784647chr16:28506595ENST00000377795-1673_2960280.6666666666667Topological domainExtracellular
HgeneCD74chr5:149784647chr16:28506595ENST00000377795-1647_720280.6666666666667TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for CD74-APOBR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14615_14615_1_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000328423_length(transcript)=3516nt_BP=539nt
AGATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAAC
TGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGC
TCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGC
TGGAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCA
TGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTG
ACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGT
GGAAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCC
CATGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCC
AGAAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAAC
AGAGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCA
GAGTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTC
AGGGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAA
AGCACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGT
AGGGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAG
GCTGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCC
TCAGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAAGAGGAGGCTGACCTGCTGGGAGTCAGA
CAGACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTCCTAGAGGAGGAGGGGGATGAGGAGAGA
GAGGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAGGCTGCTGAGAGCCAGACCGCAGGGAGG
GAAGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAGGAGGCTGAGATGAGGCAGGACTTGGGG
ATCAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGAGGGAGCAGCAGGGATCCAGTGGCTGAG
CTGCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCTGAGGAGGAGCTCACAGGGGAGGAGAGT
GAGGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTCACCAAAGGCCAAGGACCTGAGCTGATG
GGGGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATGGGAGTTCTGGCCCTGAGCAAAGAGGAG
CAGGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAGGCCTTCCCAGGAGCCTGGGAAAACCGC
ACGAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAGGAGGAGGAGACTGCGGGAGGCCAGACC
CTGGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGGGAGGGGCTGACAACCCAGGACGCGGGA
TGTGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGGGCAGACGCAGGGCCTTGCCCGTCACTG
GGAGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGAGGCTGGAGGCTGCAAGCGGTGGCTGTG
GGCCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGATGTGGTCCCACACATCAGCGCTGCTGGC
GCTGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCAGCAGCAGGAGAGCATGCAGGTGGGCAA
GAATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCTTTTGAGTCCAGGGAGGGAGGACCTTGG
GGAGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCGGGCTCCCAGACAGCGAGGGCAGAGGGG
ATGGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCTGTTGGATGGCAGGAGAGAGAACAGAGG
GAAGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGATGCAGAGGGTCTCATGGTGACCGGGGGC
CGGAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAGCAGCCAACACACCAGGCCCCTGCAGAA
GCTGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGTGCTGCCAACAGCTGGAGCGAGGCCCCG
CTCCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCCTCACAGCGTCGCTCCCGGCCCTCTTTT
CGTCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAGCTGTCAGCTCCTGAGCAGAGACCCCTC
CAGCTGGAGGAACCCCTGGAGCCAAGGTGGGAGGATCGCTTGAGACCAGGAGTTCGAGACCAGCCTGGGCAGCATAGCAAGATCCCCATC

>14615_14615_1_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000328423_length(amino acids)=989AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREA
VGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEA
AQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTR
KDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGE
AYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEF
GLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQRED
SEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLP

--------------------------------------------------------------
>14615_14615_2_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000431282_length(transcript)=3710nt_BP=539nt
AGATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAAC
TGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGC
TCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGC
TGGAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCA
TGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTG
ACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGT
GGAAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCC
CATGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCC
AGAAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAAC
AGAGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCA
GAGTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTC
AGGGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAA
AGCACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGT
AGGGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAG
GCTGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCC
TCAGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAAGAGGAGGCTGACCTGCTGGGAGTCAGA
CAGACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTCCTAGAGGAGGAGGGGGATGAGGAGAGA
GAGGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAGGCTGCTGAGAGCCAGACCGCAGGGAGG
GAAGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAGGAGGCTGAGATGAGGCAGGACTTGGGG
ATCAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGAGGGAGCAGCAGGGATCCAGTGGCTGAG
CTGCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCTGAGGAGGAGCTCACAGGGGAGGAGAGT
GAGGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTCACCAAAGGCCAAGGACCTGAGCTGATG
GGGGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATGGGAGTTCTGGCCCTGAGCAAAGAGGAG
CAGGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAGGCCTTCCCAGGAGCCTGGGAAAACCGC
ACGAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAGGAGGAGGAGACTGCGGGAGGCCAGACC
CTGGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGGGAGGGGCTGACAACCCAGGACGCGGGA
TGTGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGGGCAGACGCAGGGCCTTGCCCGTCACTG
GGAGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGAGGCTGGAGGCTGCAAGCGGTGGCTGTG
GGCCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGATGTGGTCCCACACATCAGCGCTGCTGGC
GCTGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCAGCAGCAGGAGAGCATGCAGGTGGGCAA
GAATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCTTTTGAGTCCAGGGAGGGAGGACCTTGG
GGAGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCGGGCTCCCAGACAGCGAGGGCAGAGGGG
ATGGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCTGTTGGATGGCAGGAGAGAGAACAGAGG
GAAGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGATGCAGAGGGTCTCATGGTGACCGGGGGC
CGGAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAGCAGCCAACACACCAGGCCCCTGCAGAA
GCTGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGTGCTGCCAACAGCTGGAGCGAGGCCCCG
CTCCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCCTCACAGCGTCGCTCCCGGCCCTCTTTT
CGTCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAGCTGTCAGCTCCTGAGCAGAGACCCCTC
CAGCTGGAGGAACCCCTGGAGCCAAGCCCTCTGAGGCATGATGGGACCCCGGTGCCAGCCAGGAGAAGGCCCCTGGGACACGGGTTTGGC
CTCGCGCACCCTGGCATGATGCAGGAGCTGCAAGCCCGTCTGGGCCGGCCTAAGCCCCAGTGACTGAGACCCGGTGCTCTGGGAGCCAGG
CCCTGAGTGGGTGCCAGAAGGCTTGCTCCAATGCCACTGAGCCCTGCTCCCTCTGCCACTGTGGACACATCCTCTCCACCCTCTGGGCCT

>14615_14615_2_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000431282_length(amino acids)=1008AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREA
VGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEA
AQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTR
KDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGE
AYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEF
GLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQRED
SEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLP
GSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRRPLGHGFGLA

--------------------------------------------------------------
>14615_14615_3_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000564831_length(transcript)=4065nt_BP=539nt
AGATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAAC
TGCCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGC
TCCTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGC
TGGAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCA
TGGGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTG
ACCCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGT
GGAAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCC
CATGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCC
AGAAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAAC
AGAGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCA
GAGTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTC
AGGGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAA
AGCACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGT
AGGGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAG
GCTGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCC
TCAGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAA
GAGGAGGCTGACCTGCTGGGAGTCAGACAGACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTC
CTAGAGGAGGAGGGGGATGAGGAGAGAGAGGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAG
GCTGCTGAGAGCCAGACCGCAGGGAGGGAAGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAG
GAGGCTGAGATGAGGCAGGACTTGGGGATCAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGA
GGGAGCAGCAGGGATCCAGTGGCTGAGCTGCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCT
GAGGAGGAGCTCACAGGGGAGGAGAGTGAGGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTC
ACCAAAGGCCAAGGACCTGAGCTGATGGGGGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATG
GGAGTTCTGGCCCTGAGCAAAGAGGAGCAGGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAG
GCCTTCCCAGGAGCCTGGGAAAACCGCACGAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAG
GAGGAGGAGACTGCGGGAGGCCAGACCCTGGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGG
GAGGGGCTGACAACCCAGGACGCGGGATGTGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGG
GCAGACGCAGGGCCTTGCCCGTCACTGGGAGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGA
GGCTGGAGGCTGCAAGCGGTGGCTGTGGGCCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGAT
GTGGTCCCACACATCAGCGCTGCTGGCGCTGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCA
GCAGCAGGAGAGCATGCAGGTGGGCAAGAATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCT
TTTGAGTCCAGGGAGGGAGGACCTTGGGGAGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCG
GGCTCCCAGACAGCGAGGGCAGAGGGGATGGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCT
GTTGGATGGCAGGAGAGAGAACAGAGGGAAGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGAT
GCAGAGGGTCTCATGGTGACCGGGGGCCGGAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAG
CAGCCAACACACCAGGCCCCTGCAGAAGCTGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGT
GCTGCCAACAGCTGGAGCGAGGCCCCGCTCCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCC
TCACAGCGTCGCTCCCGGCCCTCTTTTCGTCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAG
CTGTCAGCTCCTGAGCAGAGACCCCTCCAGCTGGAGGAACCCCTGGAGCCAAGCCCTCTGAGGCATGATGGGACCCCGGTGCCAGCCAGG
AGAAGGCCCCTGGGACACGGGTTTGGCCTCGCGCACCCTGGCATGATGCAGGAGCTGCAAGCCCGTCTGGGCCGGCCTAAGCCCCAGTGA
CTGAGACCCGGTGCTCTGGGAGCCAGGCCCTGAGTGGGTGCCAGAAGGCTTGCTCCAATGCCACTGAGCCCTGCTCCCTCTGCCACTGTG
GACACATCCTCTCCACCCTCTGGGCCTCAGTGTCTTGATGTATCATTCATGGAGCAGGCAAAACCAGACGTCTGGGAAGACCGTGAACTT
AAGGAGTCTGATTCTCCGACACAGGCTGGTGGACCACCTACCCCACTGAGACCACCTCTCAGGGTGCCTGCCCTGGTTCCTCCCCAGCCT
GAGTCAGCTGTCTGGACTGCAAGGAGGCTGGGCACGGGGGCTCACGCCTGTCACCCCAGAGCTTTGGGAGGCCAAGGTGGGAGGATCGCT
TGAGACCAGGAGTTCGAGACCAGCCTGGGCAGCATAGCAAGATCCCCATCTTTTAAAAACAAAATAAAACAATAAAGACTGCAAGGAAGA

>14615_14615_3_CD74-APOBR_CD74_chr5_149784647_ENST00000009530_APOBR_chr16_28506595_ENST00000564831_length(amino acids)=1017AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAA
ESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEE
ELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAF
PGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGAD
AGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAA
GEHAGGQEFGLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVG
WQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAA
NSWSEAPLPGSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRR

--------------------------------------------------------------
>14615_14615_4_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000328423_length(transcript)=3694nt_BP=717nt
GGGAGCCCCCCCGCCCCACATCCTGCCCCGCAAAAGGCAGCTTCACCAAAGTGGGGTATTTCCAGCCTTTGTAGCTTTCACTTCCACATC
TACCAAGTGGGCGGAGTGGCCTTCTGTGGACGAATCAGATTCCTCTCCAGCACCGACTTTAAGAGGCGAGCCGGGGGGTCAGGGTCCCAG
ATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTG
CCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTC
CTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTG
GAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATG
GGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGAC
CCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGTGG
AAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCCCA
TGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCCAG
AAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAACAG
AGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCAGA
GTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTCAG
GGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAAAG
CACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGTAG
GGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAGGC
TGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCCTC
AGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAAGAGGAGGCTGACCTGCTGGGAGTCAGACA
GACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTCCTAGAGGAGGAGGGGGATGAGGAGAGAGA
GGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAGGCTGCTGAGAGCCAGACCGCAGGGAGGGA
AGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAGGAGGCTGAGATGAGGCAGGACTTGGGGAT
CAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGAGGGAGCAGCAGGGATCCAGTGGCTGAGCT
GCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCTGAGGAGGAGCTCACAGGGGAGGAGAGTGA
GGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTCACCAAAGGCCAAGGACCTGAGCTGATGGG
GGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATGGGAGTTCTGGCCCTGAGCAAAGAGGAGCA
GGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAGGCCTTCCCAGGAGCCTGGGAAAACCGCAC
GAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAGGAGGAGGAGACTGCGGGAGGCCAGACCCT
GGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGGGAGGGGCTGACAACCCAGGACGCGGGATG
TGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGGGCAGACGCAGGGCCTTGCCCGTCACTGGG
AGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGAGGCTGGAGGCTGCAAGCGGTGGCTGTGGG
CCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGATGTGGTCCCACACATCAGCGCTGCTGGCGC
TGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCAGCAGCAGGAGAGCATGCAGGTGGGCAAGA
ATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCTTTTGAGTCCAGGGAGGGAGGACCTTGGGG
AGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCGGGCTCCCAGACAGCGAGGGCAGAGGGGAT
GGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCTGTTGGATGGCAGGAGAGAGAACAGAGGGA
AGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGATGCAGAGGGTCTCATGGTGACCGGGGGCCG
GAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAGCAGCCAACACACCAGGCCCCTGCAGAAGC
TGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGTGCTGCCAACAGCTGGAGCGAGGCCCCGCT
CCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCCTCACAGCGTCGCTCCCGGCCCTCTTTTCG
TCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAGCTGTCAGCTCCTGAGCAGAGACCCCTCCA
GCTGGAGGAACCCCTGGAGCCAAGGTGGGAGGATCGCTTGAGACCAGGAGTTCGAGACCAGCCTGGGCAGCATAGCAAGATCCCCATCTT

>14615_14615_4_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000328423_length(amino acids)=990AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREA
VGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEA
AQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTR
KDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGE
AYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEF
GLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQRED
SEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLP
GSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPRWEDRLRPGVRDQPGQHSKIPIFX

--------------------------------------------------------------
>14615_14615_5_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000431282_length(transcript)=3888nt_BP=717nt
GGGAGCCCCCCCGCCCCACATCCTGCCCCGCAAAAGGCAGCTTCACCAAAGTGGGGTATTTCCAGCCTTTGTAGCTTTCACTTCCACATC
TACCAAGTGGGCGGAGTGGCCTTCTGTGGACGAATCAGATTCCTCTCCAGCACCGACTTTAAGAGGCGAGCCGGGGGGTCAGGGTCCCAG
ATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTG
CCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTC
CTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTG
GAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATG
GGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGAC
CCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGTGG
AAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCCCA
TGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCCAG
AAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAACAG
AGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCAGA
GTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTCAG
GGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAAAG
CACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGTAG
GGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAGGC
TGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCCTC
AGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAAGAGGAGGCTGACCTGCTGGGAGTCAGACA
GACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTCCTAGAGGAGGAGGGGGATGAGGAGAGAGA
GGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAGGCTGCTGAGAGCCAGACCGCAGGGAGGGA
AGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAGGAGGCTGAGATGAGGCAGGACTTGGGGAT
CAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGAGGGAGCAGCAGGGATCCAGTGGCTGAGCT
GCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCTGAGGAGGAGCTCACAGGGGAGGAGAGTGA
GGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTCACCAAAGGCCAAGGACCTGAGCTGATGGG
GGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATGGGAGTTCTGGCCCTGAGCAAAGAGGAGCA
GGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAGGCCTTCCCAGGAGCCTGGGAAAACCGCAC
GAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAGGAGGAGGAGACTGCGGGAGGCCAGACCCT
GGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGGGAGGGGCTGACAACCCAGGACGCGGGATG
TGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGGGCAGACGCAGGGCCTTGCCCGTCACTGGG
AGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGAGGCTGGAGGCTGCAAGCGGTGGCTGTGGG
CCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGATGTGGTCCCACACATCAGCGCTGCTGGCGC
TGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCAGCAGCAGGAGAGCATGCAGGTGGGCAAGA
ATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCTTTTGAGTCCAGGGAGGGAGGACCTTGGGG
AGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCGGGCTCCCAGACAGCGAGGGCAGAGGGGAT
GGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCTGTTGGATGGCAGGAGAGAGAACAGAGGGA
AGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGATGCAGAGGGTCTCATGGTGACCGGGGGCCG
GAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAGCAGCCAACACACCAGGCCCCTGCAGAAGC
TGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGTGCTGCCAACAGCTGGAGCGAGGCCCCGCT
CCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCCTCACAGCGTCGCTCCCGGCCCTCTTTTCG
TCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAGCTGTCAGCTCCTGAGCAGAGACCCCTCCA
GCTGGAGGAACCCCTGGAGCCAAGCCCTCTGAGGCATGATGGGACCCCGGTGCCAGCCAGGAGAAGGCCCCTGGGACACGGGTTTGGCCT
CGCGCACCCTGGCATGATGCAGGAGCTGCAAGCCCGTCTGGGCCGGCCTAAGCCCCAGTGACTGAGACCCGGTGCTCTGGGAGCCAGGCC
CTGAGTGGGTGCCAGAAGGCTTGCTCCAATGCCACTGAGCCCTGCTCCCTCTGCCACTGTGGACACATCCTCTCCACCCTCTGGGCCTCA

>14615_14615_5_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000431282_length(amino acids)=1008AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREA
VGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEA
AQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTR
KDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGE
AYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEF
GLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQRED
SEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLP
GSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRRPLGHGFGLA

--------------------------------------------------------------
>14615_14615_6_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000564831_length(transcript)=4243nt_BP=717nt
GGGAGCCCCCCCGCCCCACATCCTGCCCCGCAAAAGGCAGCTTCACCAAAGTGGGGTATTTCCAGCCTTTGTAGCTTTCACTTCCACATC
TACCAAGTGGGCGGAGTGGCCTTCTGTGGACGAATCAGATTCCTCTCCAGCACCGACTTTAAGAGGCGAGCCGGGGGGTCAGGGTCCCAG
ATGCACAGGAGGAGAAGCAGGAGCTGTCGGGAAGATCAGAAGCCAGTCATGGATGACCAGCGCGACCTTATCTCCAACAATGAGCAACTG
CCCATGCTGGGCCGGCGCCCTGGGGCCCCGGAGAGCAAGTGCAGCCGCGGAGCCCTGTACACAGGCTTTTCCATCCTGGTGACTCTGCTC
CTCGCTGGCCAGGCCACCACCGCCTACTTCCTGTACCAGCAGCAGGGCCGGCTGGACAAACTGACAGTCACCTCCCAGAACCTGCAGCTG
GAGAACCTGCGCATGAAGCTTCCCAAGCCTCCCAAGCCTGTGAGCAAGATGCGCATGGCCACCCCGCTGCTGATGCAGGCGCTGCCCATG
GGAGCCCTGCCCCAGGGGCCCATGCAGAATGCCACCAAGTATGGCAACATGACAGAGGACCATGTGATGCACCTGCTCCAGAATGCTGAC
CCCCTGAAGGTGTACCCGCCACTGAAGGGGAGCTTCCCGGAGAACCTGAGACACCTTAAGAACACCATGGAGACCATAGACTGGAAGTGG
AAGGCTGAGAGGGCCTGGAGATGACAGAAGACATGAAGTGGGGAGCTCAGCTGTAGAACAGACCTGGGGCTGGGGAGATGGCAGCTCCCA
TGGGTCCCAAGCAGAGAGGCAGGACAGTGGGGCTGGGGAGACAGCCAAGGCTGCCAGGTGCCAGGAGCCAAGCGCCCACTTGGAGGCCAG
AAAGAAATCCAAGGCAGGGTCTGGGGCTTGCCAAGACAGGAGCGGCCAAGCCCAGGAGAGGCAGGAGTCCCATGAGCAGGAAGTGAACAG
AGAAGAGAGGCTGAGAAGCTGGGAACAGGAGGAGGAGGAGGAAGAGGTCAGGGCAAGAGAGCCAGGGATGGCCAGAGGGGCGGAGTCAGA
GTGGACCTGGCATGGGGAGACGGAGGGGAAGGCTGGTGCTGTTGGGCCAAAGGCGGCAGGGGACAACCGGGAGATGGAGCAGGGGGTCAG
GGAGGCAGATGCAGGGGAAACTGAGGAGCCTGGGGCCGAAGGGGCTGGGAAAGGAGAAGAGGTGGTAGTGGTGGAGAAGGCCTGTGAAAG
CACTAGGGCATGGGGGACGTGGGGCCCAGGGGCAGAGCCTGAGGACTGGGGAATCTTAGGCAGAGAGGAGGCCAGGACAACCCCAGGTAG
GGAAGAGGCCAGGGCAATTTTAGATGGGGAGGAAGCCAGGACAATCTCAGGCGGGGAGGAGGCTGAGACAGCCTCAGGCGGGGAGGAGGC
TGAAACAGCCTCAGGCGGGGAGGAGGCCGGGACAGCCTCGGGAGGGGAGGAGGCCGGGATAGCCTCAGGCGGGGAGGCTGGGACAGCCTC
AGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGAGGAGGCCGGGACAGCCTCAGGAGGGGACGAGGCCTGGACAACCTCAGGCAAAGA
GGAGGCTGACCTGCTGGGAGTCAGACAGACAGAATATGGAGCAGTCCCAGGAGAAAGGCTCCTAGAGGCTACTGGAAAAGTCTGGGTCCT
AGAGGAGGAGGGGGATGAGGAGAGAGAGGCTGAGGTGAGCCCTTTCCCCAAACAGCCCCAGGTCCTGGGCACTGAAAGAACAGAAGAGGC
TGCTGAGAGCCAGACCGCAGGGAGGGAAGCTGTGGGAGGCCAGGAGGCAGGGGAGAGCTTTGAGGGCCAGGTAGACCTGCGTGGTAAGGA
GGCTGAGATGAGGCAGGACTTGGGGATCAGGGCCGACCGGGCCAGGATGGAAGAGCTGGTACAGGCAGAGGAGGCCCAGGAGGAGAGAGG
GAGCAGCAGGGATCCAGTGGCTGAGCTGCCCTCAGATGGAGAGGCTGAAGGCACTGCCGACTTGGAGGCAACTCCAGAGGCCAGGCCTGA
GGAGGAGCTCACAGGGGAGGAGAGTGAGGCGGCCCAGACTAGCTGTGGCCTACTGGGCGTGGAATGGGGTGGCCTCACACACAGCGTCAC
CAAAGGCCAAGGACCTGAGCTGATGGGGGGCGCCCAGACCCCAACTAAGCAACCCGAGGAAAGGGAGGCAGGGGAGGTGGAGCTCATGGG
AGTTCTGGCCCTGAGCAAAGAGGAGCAGGAGAGGAGCCTGGAGGCAGGTCCCAGGCACGCGGGGTCTGTAAAGCCTGAGGCCTCCGAGGC
CTTCCCAGGAGCCTGGGAAAACCGCACGAGAAAGGACATGGAGAGAGGAAATACTCAGGAGGATGCGGCCGATGGCGAGCAGCGGGAGGA
GGAGGAGACTGCGGGAGGCCAGACCCTGGCGGCTGAGGCTGAAGGAGACCGAGAGTCTGAACTATCAGAAGTCCCAGAGGCAGGCGGGGA
GGGGCTGACAACCCAGGACGCGGGATGTGGAACTGAGGAGGGAGAGGCATCTGTCTCAGAGAACCAGGAGCTGGACGGAAGCACAGGGGC
AGACGCAGGGCCTTGCCCGTCACTGGGAGAGGCCTATGCCAGAGAAACTGAGGATGAGGAGGCGGAGGCTGACAGAACATCCAGAAGAGG
CTGGAGGCTGCAAGCGGTGGCTGTGGGCCTCCCGGACCGTGAGGATGCACAGACTGGCTCTGTGGCTGCTGGGATTATGGGGGGTGATGT
GGTCCCACACATCAGCGCTGCTGGCGCTGGTGAAGCTTTGGAAGGGGTGCTTGGGCAAGGCTGGGACTCGAAAGAAAAGGAAGAGGCAGC
AGCAGGAGAGCATGCAGGTGGGCAAGAATTTGGTCTGGAGGGCTCAGCAGAGGAAGAGGTGACTGGCAGAGGCAGCCAAGTAGAGGCTTT
TGAGTCCAGGGAGGGAGGACCTTGGGGAGGGCGGGTAGAGGCCGAGGAATCTGCAGGCGCAGAGGACAGCTGTGGGCTGGATCCCGCGGG
CTCCCAGACAGCGAGGGCAGAGGGGATGGGAGCCATGGTGGAGGCTGGGGGGCTTCTAGAAAAGTGGACGCTGTTGGAAGAAGAGGCTGT
TGGATGGCAGGAGAGAGAACAGAGGGAAGACAGTGAGGGGCGGTGTGGGGACTACCACCCTGAGGGAGAGGCACCAAGGCTCCTTGATGC
AGAGGGTCTCATGGTGACCGGGGGCCGGAGGGCAGAGGCCAAGGAGACTGAGCCAGAAAGCCTGGAACATGTCAGGGGCCAGGAGGAGCA
GCCAACACACCAGGCCCCTGCAGAAGCTGCGCCGGAGTCAGTCGGGGAAGCCGAGACGGCTGAGGCCATGGGCAGTGCCAGAGGAGGTGC
TGCCAACAGCTGGAGCGAGGCCCCGCTCCCCGGGTCCCTCCTAGACGTCTCTGTCCCAAGGAGTCGCGTGCACCTCTCGAGAAGCTCCTC
ACAGCGTCGCTCCCGGCCCTCTTTTCGTCGGACTCCGGCCTGGGAGCAGCAGGAGGAGCCCCCAGCCCCCAACCCTCCTGAGGAGGAGCT
GTCAGCTCCTGAGCAGAGACCCCTCCAGCTGGAGGAACCCCTGGAGCCAAGCCCTCTGAGGCATGATGGGACCCCGGTGCCAGCCAGGAG
AAGGCCCCTGGGACACGGGTTTGGCCTCGCGCACCCTGGCATGATGCAGGAGCTGCAAGCCCGTCTGGGCCGGCCTAAGCCCCAGTGACT
GAGACCCGGTGCTCTGGGAGCCAGGCCCTGAGTGGGTGCCAGAAGGCTTGCTCCAATGCCACTGAGCCCTGCTCCCTCTGCCACTGTGGA
CACATCCTCTCCACCCTCTGGGCCTCAGTGTCTTGATGTATCATTCATGGAGCAGGCAAAACCAGACGTCTGGGAAGACCGTGAACTTAA
GGAGTCTGATTCTCCGACACAGGCTGGTGGACCACCTACCCCACTGAGACCACCTCTCAGGGTGCCTGCCCTGGTTCCTCCCCAGCCTGA
GTCAGCTGTCTGGACTGCAAGGAGGCTGGGCACGGGGGCTCACGCCTGTCACCCCAGAGCTTTGGGAGGCCAAGGTGGGAGGATCGCTTG
AGACCAGGAGTTCGAGACCAGCCTGGGCAGCATAGCAAGATCCCCATCTTTTAAAAACAAAATAAAACAATAAAGACTGCAAGGAAGACT

>14615_14615_6_CD74-APOBR_CD74_chr5_149784647_ENST00000353334_APOBR_chr16_28506595_ENST00000564831_length(amino acids)=1017AA_BP=194
MRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNRE
ERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACEST
RAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASG
GEEAGTASGGEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAA
ESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEE
ELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAF
PGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGAD
AGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAA
GEHAGGQEFGLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVG
WQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAA
NSWSEAPLPGSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRR

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Fusion Gene PPI Analysis for CD74-APOBR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD74-APOBR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CD74-APOBR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource