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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CD99-DHRSX (FusionGDB2 ID:14713) |
Fusion Gene Summary for CD99-DHRSX |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CD99-DHRSX | Fusion gene ID: 14713 | Hgene | Tgene | Gene symbol | CD99 | DHRSX | Gene ID | 4267 | 207063 |
| Gene name | CD99 molecule (Xg blood group) | dehydrogenase/reductase X-linked | |
| Synonyms | HBA71|MIC2|MIC2X|MIC2Y|MSK5X | CXorf11|DHRS5X|DHRS5Y|DHRSXY|DHRSY|SDR46C1|SDR7C6 | |
| Cytomap | Xp22.33 and Yp11.2 | Xp22.33 and Yp11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CD99 antigenE2 antigenMIC2 (monoclonal antibody 12E7)T-cell surface glycoprotein E2antigen identified by monoclonal 12E7, Y homologantigen identified by monoclonal antibodies 12E7, F21 and O13cell surface antigen 12E7cell surface antigen HBA-71cel | dehydrogenase/reductase SDR family member on chromosome Xdehydrogenase/reductase (SDR family) X chromosomedehydrogenase/reductase (SDR family) X-linkeddehydrogenase/reductase (SDR family) Y-linkedshort chain dehydrogenase/reductase family 46C member 1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | P14209 | Q8N5I4 | |
| Ensembl transtripts involved in fusion gene | ENST00000482405, ENST00000381180, ENST00000381184, ENST00000381187, ENST00000381192, | ENST00000334651, ENST00000464935, | |
| Fusion gene scores | * DoF score | 16 X 8 X 2=256 | 17 X 16 X 8=2176 |
| # samples | 16 | 17 | |
| ** MAII score | log2(16/256*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(17/2176*10)=-3.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CD99 [Title/Abstract] AND DHRSX [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CD99(2559468)-DHRSX(2159644), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across CD99 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DHRSX (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LGG | TCGA-DU-7299 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
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Fusion Gene ORF analysis for CD99-DHRSX |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000482405 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| 3UTR-intron | ENST00000482405 | ENST00000464935 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| 5CDS-intron | ENST00000381180 | ENST00000464935 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| 5CDS-intron | ENST00000381184 | ENST00000464935 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| 5CDS-intron | ENST00000381187 | ENST00000464935 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| 5CDS-intron | ENST00000381192 | ENST00000464935 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| In-frame | ENST00000381180 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| In-frame | ENST00000381184 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| In-frame | ENST00000381187 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| In-frame | ENST00000381192 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000381192 | CD99 | chrY | 2559468 | + | ENST00000334651 | DHRSX | chrY | 2159644 | - | 2481 | 249 | 143 | 955 | 270 |
| ENST00000381187 | CD99 | chrY | 2559468 | + | ENST00000334651 | DHRSX | chrY | 2159644 | - | 2384 | 152 | 46 | 858 | 270 |
| ENST00000381184 | CD99 | chrY | 2559468 | + | ENST00000334651 | DHRSX | chrY | 2159644 | - | 2380 | 148 | 42 | 854 | 270 |
| ENST00000381180 | CD99 | chrY | 2559468 | + | ENST00000334651 | DHRSX | chrY | 2159644 | - | 2299 | 67 | 0 | 773 | 257 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000381192 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - | 0.000985817 | 0.99901414 |
| ENST00000381187 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - | 0.000906659 | 0.9990933 |
| ENST00000381184 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - | 0.000987612 | 0.99901235 |
| ENST00000381180 | ENST00000334651 | CD99 | chrY | 2559468 | + | DHRSX | chrY | 2159644 | - | 0.000875789 | 0.9991242 |
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Fusion Genomic Features for CD99-DHRSX |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CD99-DHRSX |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrY:2559468/chrY:2159644) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CD99 | DHRSX |
| FUNCTION: Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity). {ECO:0000250}. | FUNCTION: Involved in the positive regulation of starvation-induced autophagy (PubMed:25076851). {ECO:0000269|PubMed:25076851}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381187 | + | 1 | 9 | 148_185 | 22 | 170.0 | Topological domain | Cytoplasmic |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381187 | + | 1 | 9 | 23_122 | 22 | 170.0 | Topological domain | Extracellular |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381192 | + | 1 | 10 | 148_185 | 22 | 186.0 | Topological domain | Cytoplasmic |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381192 | + | 1 | 10 | 23_122 | 22 | 186.0 | Topological domain | Extracellular |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381187 | + | 1 | 9 | 123_147 | 22 | 170.0 | Transmembrane | Helical |
| Hgene | CD99 | chrY:2559468 | chrY:2159644 | ENST00000381192 | + | 1 | 10 | 123_147 | 22 | 186.0 | Transmembrane | Helical |
| Tgene | DHRSX | chrY:2559468 | chrY:2159644 | ENST00000334651 | 2 | 7 | 47_71 | 95 | 331.0 | Nucleotide binding | NAD or NADP |
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Fusion Gene Sequence for CD99-DHRSX |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >14713_14713_1_CD99-DHRSX_CD99_chrY_2559468_ENST00000381180_DHRSX_chrY_2159644_ENST00000334651_length(transcript)=2299nt_BP=67nt ATGGCCCGCGGGGCTGCGCTGGCGCTGCTGCTCTTCGGCCTGCTGGGTGTTCTGGTCGCCGCCCCGGTGGAATTTTTATACTGTGACTTG GCTTCCATGACTTCCATCCGGCAGTTTGTGCAGAAGTTCAAGATGAAGAAGATTCCTCTCCATGTCCTGATCAACAATGCTGGGGTGATG ATGGTCCCTCAGAGGAAAACCAGAGATGGATTCGAAGAACATTTCGGCCTGAACTACCTAGGGCACTTCCTGCTGACCAACCTTCTCTTG GATACGCTGAAAGAGTCTGGGTCCCCTGGCCACAGTGCGAGGGTGGTCACCGTCTCCTCTGCCACCCATTACGTCGCTGAGCTGAACATG GATGACCTTCAGAGCAGTGCCTGCTACTCACCCCACGCAGCCTACGCCCAGAGCAAGCTGGCCCTTGTCCTGTTCACCTACCACCTCCAG CGGCTGCTGGCGGCTGAGGGAAGCCACGTGACCGCCAACGTGGTGGACCCCGGGGTGGTCAACACGGACGTCTACAAGCACGTGTTCTGG GCCACCCGTCTGGCGAAGAAGCTTCTCGGCTGGTTGCTTTTCAAGACCCCCGATGAAGGAGCGTGGACTTCCATCTACGCAGCAGTCACC CCAGAGCTGGAAGGAGTTGGTGGCCATTACCTATACAACGAGAAAGAGACCAAGTCCCTCCACGTCACCTACAACCAGAAACTGCAGCAG CAGCTGTGGTCTAAGAGTTGTGAGATGACTGGGGTCCTTGATGTGACCCTGTGATATCCTGTCTCAGGATAGCTGCTGCCCCAAGAAACA CATTGCACCTGCCAATAGCTTGTGGGTCTGTGAAGACTGCGGTGTTTGAGTTTCTCACACCCACCTGCCCACAGGGCTCTGTCCTCTAGT TTTGAGACAGCTGCCTCAACCTCTGCAGAACTTCAAGAAGCCAAATAAACATTTTGGAGGATAATCACCCCAAGTGGTCTTCAACCATAA ACTTTGTGATTCCAAAGTGCCCAGTTGTCACAGGTGCCATAAATAATTACATTTTCCAACATAAATGTGCCATTTTCCTTGCCGCGTTAA TACAACTGAGTACAAAAGTTCCAAGAGAGATGCTCTCTTTTCAGGGGCTGCAATGTCCTCTCTGAGACCTAGTGGTGGATGAGGTCTCCT GTTTGATTTTGTTCCTGCACTCACTCATTTTTCCAGAGACCCAGCTGTGATTCACAGGTGTCAGACATGGGGAGGTGTGAGCCTTGCTTG CTACAGCCTGTAGGATGAGTTTGACGTGGCCAGCAGCACCATCTGGTCAACCTCATTCCAGAATGGCACAGTCACAAGTGAAGCATGCCA CTGTCAAATCCGAGAATGTAAACCGCTGAACAGCTATGGATCAAATGGTAGCCCTCAAAAGATATGTTCATGCCCTAACCCTCAGAACCT ATAAATATTACTTTATTTGGAAAAGAATCTTTGCAGATAGAATTAAGAATTTTGAGATGGGTCATTATGGATCATCCCAGTGAACCTAAT GCCATCACGAGGGTTCTTATCAGAGACAGGTAGAGGGAGATTTGAGTACAGAAGACAAGATATTCGTGTGATGATGCAGACAGAGACTGG AGTGATGCCACCACAAGCCAAGCAATGCCTGGAGCCACCAGGAGCTGGGACAGGCAGGAAGGATTCTCCCTTATACCCCTCAGAGCAATC TTGGCCCCTCTGACGTCTTGACTTTAGACTTCTGGTCCCCAGAACGGAGAGAGAATAAATCTTTCTTGTTTTAAGGCTCCAACAAATTGG TAGTCACTTGTTACAGCAACCACAGGAAATGTATACAGCTTCTGATACTTCTGAAAACCTCACACAGCCAAAGGGTACATCCTTGGTATA GAGGCTCACTCTTACTCACCAGCCAGGCAAGGAAGGCTCAATCCTTTGGTGTTAGAGAGATAGATGTTGGGTTTTCAAATTTCAACATAG AGAAATCAGTCATTTGCAATGCTTTTGAGAAAGTACTGTGTATACCCTACGAGCCTGCACTCCTTATGTGTGAGACTGATGACCATTGGT TGGCTTATTATCCATTCCACTAAGTGACAAAATCCCACTGACTATTCAAATCCAGGCTCCTGGCATGCCTGTACCTTAGAATCACAACCA GCTGCAATTCCAGGATGGAGTTCAAACTAATTGTGGGGGCATGTGCTTCTTACATGACTGCTAGATTGTTCCCAGATGGGGAAGGTTGCC >14713_14713_1_CD99-DHRSX_CD99_chrY_2559468_ENST00000381180_DHRSX_chrY_2159644_ENST00000334651_length(amino acids)=257AA_BP=21 MARGAALALLLFGLLGVLVAAPVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHVFW -------------------------------------------------------------- >14713_14713_2_CD99-DHRSX_CD99_chrY_2559468_ENST00000381184_DHRSX_chrY_2159644_ENST00000334651_length(transcript)=2380nt_BP=148nt GGCCCGTGGGGGAGTATCTGTCCTGCCGCCTTCGCCCACGCCCTGCACTCCGGGACCGTCCCTGCGCGCTCTGGGCGCACCATGGCCCGC GGGGCTGCGCTGGCGCTGCTGCTCTTCGGCCTGCTGGGTGTTCTGGTCGCCGCCCCGGTGGAATTTTTATACTGTGACTTGGCTTCCATG ACTTCCATCCGGCAGTTTGTGCAGAAGTTCAAGATGAAGAAGATTCCTCTCCATGTCCTGATCAACAATGCTGGGGTGATGATGGTCCCT CAGAGGAAAACCAGAGATGGATTCGAAGAACATTTCGGCCTGAACTACCTAGGGCACTTCCTGCTGACCAACCTTCTCTTGGATACGCTG AAAGAGTCTGGGTCCCCTGGCCACAGTGCGAGGGTGGTCACCGTCTCCTCTGCCACCCATTACGTCGCTGAGCTGAACATGGATGACCTT CAGAGCAGTGCCTGCTACTCACCCCACGCAGCCTACGCCCAGAGCAAGCTGGCCCTTGTCCTGTTCACCTACCACCTCCAGCGGCTGCTG GCGGCTGAGGGAAGCCACGTGACCGCCAACGTGGTGGACCCCGGGGTGGTCAACACGGACGTCTACAAGCACGTGTTCTGGGCCACCCGT CTGGCGAAGAAGCTTCTCGGCTGGTTGCTTTTCAAGACCCCCGATGAAGGAGCGTGGACTTCCATCTACGCAGCAGTCACCCCAGAGCTG GAAGGAGTTGGTGGCCATTACCTATACAACGAGAAAGAGACCAAGTCCCTCCACGTCACCTACAACCAGAAACTGCAGCAGCAGCTGTGG TCTAAGAGTTGTGAGATGACTGGGGTCCTTGATGTGACCCTGTGATATCCTGTCTCAGGATAGCTGCTGCCCCAAGAAACACATTGCACC TGCCAATAGCTTGTGGGTCTGTGAAGACTGCGGTGTTTGAGTTTCTCACACCCACCTGCCCACAGGGCTCTGTCCTCTAGTTTTGAGACA GCTGCCTCAACCTCTGCAGAACTTCAAGAAGCCAAATAAACATTTTGGAGGATAATCACCCCAAGTGGTCTTCAACCATAAACTTTGTGA TTCCAAAGTGCCCAGTTGTCACAGGTGCCATAAATAATTACATTTTCCAACATAAATGTGCCATTTTCCTTGCCGCGTTAATACAACTGA GTACAAAAGTTCCAAGAGAGATGCTCTCTTTTCAGGGGCTGCAATGTCCTCTCTGAGACCTAGTGGTGGATGAGGTCTCCTGTTTGATTT TGTTCCTGCACTCACTCATTTTTCCAGAGACCCAGCTGTGATTCACAGGTGTCAGACATGGGGAGGTGTGAGCCTTGCTTGCTACAGCCT GTAGGATGAGTTTGACGTGGCCAGCAGCACCATCTGGTCAACCTCATTCCAGAATGGCACAGTCACAAGTGAAGCATGCCACTGTCAAAT CCGAGAATGTAAACCGCTGAACAGCTATGGATCAAATGGTAGCCCTCAAAAGATATGTTCATGCCCTAACCCTCAGAACCTATAAATATT ACTTTATTTGGAAAAGAATCTTTGCAGATAGAATTAAGAATTTTGAGATGGGTCATTATGGATCATCCCAGTGAACCTAATGCCATCACG AGGGTTCTTATCAGAGACAGGTAGAGGGAGATTTGAGTACAGAAGACAAGATATTCGTGTGATGATGCAGACAGAGACTGGAGTGATGCC ACCACAAGCCAAGCAATGCCTGGAGCCACCAGGAGCTGGGACAGGCAGGAAGGATTCTCCCTTATACCCCTCAGAGCAATCTTGGCCCCT CTGACGTCTTGACTTTAGACTTCTGGTCCCCAGAACGGAGAGAGAATAAATCTTTCTTGTTTTAAGGCTCCAACAAATTGGTAGTCACTT GTTACAGCAACCACAGGAAATGTATACAGCTTCTGATACTTCTGAAAACCTCACACAGCCAAAGGGTACATCCTTGGTATAGAGGCTCAC TCTTACTCACCAGCCAGGCAAGGAAGGCTCAATCCTTTGGTGTTAGAGAGATAGATGTTGGGTTTTCAAATTTCAACATAGAGAAATCAG TCATTTGCAATGCTTTTGAGAAAGTACTGTGTATACCCTACGAGCCTGCACTCCTTATGTGTGAGACTGATGACCATTGGTTGGCTTATT ATCCATTCCACTAAGTGACAAAATCCCACTGACTATTCAAATCCAGGCTCCTGGCATGCCTGTACCTTAGAATCACAACCAGCTGCAATT CCAGGATGGAGTTCAAACTAATTGTGGGGGCATGTGCTTCTTACATGACTGCTAGATTGTTCCCAGATGGGGAAGGTTGCCCTGATAAGC >14713_14713_2_CD99-DHRSX_CD99_chrY_2559468_ENST00000381184_DHRSX_chrY_2159644_ENST00000334651_length(amino acids)=270AA_BP=34 MHSGTVPARSGRTMARGAALALLLFGLLGVLVAAPVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGL NYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDP GVVNTDVYKHVFWATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKETKSLHVTYNQKLQQQLWSKSCEMTGVLDVTL -------------------------------------------------------------- >14713_14713_3_CD99-DHRSX_CD99_chrY_2559468_ENST00000381187_DHRSX_chrY_2159644_ENST00000334651_length(transcript)=2384nt_BP=152nt ACCCGGCCCGTGGGGGAGTATCTGTCCTGCCGCCTTCGCCCACGCCCTGCACTCCGGGACCGTCCCTGCGCGCTCTGGGCGCACCATGGC CCGCGGGGCTGCGCTGGCGCTGCTGCTCTTCGGCCTGCTGGGTGTTCTGGTCGCCGCCCCGGTGGAATTTTTATACTGTGACTTGGCTTC CATGACTTCCATCCGGCAGTTTGTGCAGAAGTTCAAGATGAAGAAGATTCCTCTCCATGTCCTGATCAACAATGCTGGGGTGATGATGGT CCCTCAGAGGAAAACCAGAGATGGATTCGAAGAACATTTCGGCCTGAACTACCTAGGGCACTTCCTGCTGACCAACCTTCTCTTGGATAC GCTGAAAGAGTCTGGGTCCCCTGGCCACAGTGCGAGGGTGGTCACCGTCTCCTCTGCCACCCATTACGTCGCTGAGCTGAACATGGATGA CCTTCAGAGCAGTGCCTGCTACTCACCCCACGCAGCCTACGCCCAGAGCAAGCTGGCCCTTGTCCTGTTCACCTACCACCTCCAGCGGCT GCTGGCGGCTGAGGGAAGCCACGTGACCGCCAACGTGGTGGACCCCGGGGTGGTCAACACGGACGTCTACAAGCACGTGTTCTGGGCCAC CCGTCTGGCGAAGAAGCTTCTCGGCTGGTTGCTTTTCAAGACCCCCGATGAAGGAGCGTGGACTTCCATCTACGCAGCAGTCACCCCAGA GCTGGAAGGAGTTGGTGGCCATTACCTATACAACGAGAAAGAGACCAAGTCCCTCCACGTCACCTACAACCAGAAACTGCAGCAGCAGCT GTGGTCTAAGAGTTGTGAGATGACTGGGGTCCTTGATGTGACCCTGTGATATCCTGTCTCAGGATAGCTGCTGCCCCAAGAAACACATTG CACCTGCCAATAGCTTGTGGGTCTGTGAAGACTGCGGTGTTTGAGTTTCTCACACCCACCTGCCCACAGGGCTCTGTCCTCTAGTTTTGA GACAGCTGCCTCAACCTCTGCAGAACTTCAAGAAGCCAAATAAACATTTTGGAGGATAATCACCCCAAGTGGTCTTCAACCATAAACTTT GTGATTCCAAAGTGCCCAGTTGTCACAGGTGCCATAAATAATTACATTTTCCAACATAAATGTGCCATTTTCCTTGCCGCGTTAATACAA CTGAGTACAAAAGTTCCAAGAGAGATGCTCTCTTTTCAGGGGCTGCAATGTCCTCTCTGAGACCTAGTGGTGGATGAGGTCTCCTGTTTG ATTTTGTTCCTGCACTCACTCATTTTTCCAGAGACCCAGCTGTGATTCACAGGTGTCAGACATGGGGAGGTGTGAGCCTTGCTTGCTACA GCCTGTAGGATGAGTTTGACGTGGCCAGCAGCACCATCTGGTCAACCTCATTCCAGAATGGCACAGTCACAAGTGAAGCATGCCACTGTC AAATCCGAGAATGTAAACCGCTGAACAGCTATGGATCAAATGGTAGCCCTCAAAAGATATGTTCATGCCCTAACCCTCAGAACCTATAAA TATTACTTTATTTGGAAAAGAATCTTTGCAGATAGAATTAAGAATTTTGAGATGGGTCATTATGGATCATCCCAGTGAACCTAATGCCAT CACGAGGGTTCTTATCAGAGACAGGTAGAGGGAGATTTGAGTACAGAAGACAAGATATTCGTGTGATGATGCAGACAGAGACTGGAGTGA TGCCACCACAAGCCAAGCAATGCCTGGAGCCACCAGGAGCTGGGACAGGCAGGAAGGATTCTCCCTTATACCCCTCAGAGCAATCTTGGC CCCTCTGACGTCTTGACTTTAGACTTCTGGTCCCCAGAACGGAGAGAGAATAAATCTTTCTTGTTTTAAGGCTCCAACAAATTGGTAGTC ACTTGTTACAGCAACCACAGGAAATGTATACAGCTTCTGATACTTCTGAAAACCTCACACAGCCAAAGGGTACATCCTTGGTATAGAGGC TCACTCTTACTCACCAGCCAGGCAAGGAAGGCTCAATCCTTTGGTGTTAGAGAGATAGATGTTGGGTTTTCAAATTTCAACATAGAGAAA TCAGTCATTTGCAATGCTTTTGAGAAAGTACTGTGTATACCCTACGAGCCTGCACTCCTTATGTGTGAGACTGATGACCATTGGTTGGCT TATTATCCATTCCACTAAGTGACAAAATCCCACTGACTATTCAAATCCAGGCTCCTGGCATGCCTGTACCTTAGAATCACAACCAGCTGC AATTCCAGGATGGAGTTCAAACTAATTGTGGGGGCATGTGCTTCTTACATGACTGCTAGATTGTTCCCAGATGGGGAAGGTTGCCCTGAT >14713_14713_3_CD99-DHRSX_CD99_chrY_2559468_ENST00000381187_DHRSX_chrY_2159644_ENST00000334651_length(amino acids)=270AA_BP=34 MHSGTVPARSGRTMARGAALALLLFGLLGVLVAAPVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGL NYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDP GVVNTDVYKHVFWATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKETKSLHVTYNQKLQQQLWSKSCEMTGVLDVTL -------------------------------------------------------------- >14713_14713_4_CD99-DHRSX_CD99_chrY_2559468_ENST00000381192_DHRSX_chrY_2159644_ENST00000334651_length(transcript)=2481nt_BP=249nt GCGCGCGTGGAGGCCGGGGCGGGGCGGGCGCAGCCGGCGCTGAGCTTGCAGGGCCGCTCCCCTCACCCGCCCCCTTCGAGTCCCCGGGCT TCGCCCCACCCGGCCCGTGGGGGAGTATCTGTCCTGCCGCCTTCGCCCACGCCCTGCACTCCGGGACCGTCCCTGCGCGCTCTGGGCGCA CCATGGCCCGCGGGGCTGCGCTGGCGCTGCTGCTCTTCGGCCTGCTGGGTGTTCTGGTCGCCGCCCCGGTGGAATTTTTATACTGTGACT TGGCTTCCATGACTTCCATCCGGCAGTTTGTGCAGAAGTTCAAGATGAAGAAGATTCCTCTCCATGTCCTGATCAACAATGCTGGGGTGA TGATGGTCCCTCAGAGGAAAACCAGAGATGGATTCGAAGAACATTTCGGCCTGAACTACCTAGGGCACTTCCTGCTGACCAACCTTCTCT TGGATACGCTGAAAGAGTCTGGGTCCCCTGGCCACAGTGCGAGGGTGGTCACCGTCTCCTCTGCCACCCATTACGTCGCTGAGCTGAACA TGGATGACCTTCAGAGCAGTGCCTGCTACTCACCCCACGCAGCCTACGCCCAGAGCAAGCTGGCCCTTGTCCTGTTCACCTACCACCTCC AGCGGCTGCTGGCGGCTGAGGGAAGCCACGTGACCGCCAACGTGGTGGACCCCGGGGTGGTCAACACGGACGTCTACAAGCACGTGTTCT GGGCCACCCGTCTGGCGAAGAAGCTTCTCGGCTGGTTGCTTTTCAAGACCCCCGATGAAGGAGCGTGGACTTCCATCTACGCAGCAGTCA CCCCAGAGCTGGAAGGAGTTGGTGGCCATTACCTATACAACGAGAAAGAGACCAAGTCCCTCCACGTCACCTACAACCAGAAACTGCAGC AGCAGCTGTGGTCTAAGAGTTGTGAGATGACTGGGGTCCTTGATGTGACCCTGTGATATCCTGTCTCAGGATAGCTGCTGCCCCAAGAAA CACATTGCACCTGCCAATAGCTTGTGGGTCTGTGAAGACTGCGGTGTTTGAGTTTCTCACACCCACCTGCCCACAGGGCTCTGTCCTCTA GTTTTGAGACAGCTGCCTCAACCTCTGCAGAACTTCAAGAAGCCAAATAAACATTTTGGAGGATAATCACCCCAAGTGGTCTTCAACCAT AAACTTTGTGATTCCAAAGTGCCCAGTTGTCACAGGTGCCATAAATAATTACATTTTCCAACATAAATGTGCCATTTTCCTTGCCGCGTT AATACAACTGAGTACAAAAGTTCCAAGAGAGATGCTCTCTTTTCAGGGGCTGCAATGTCCTCTCTGAGACCTAGTGGTGGATGAGGTCTC CTGTTTGATTTTGTTCCTGCACTCACTCATTTTTCCAGAGACCCAGCTGTGATTCACAGGTGTCAGACATGGGGAGGTGTGAGCCTTGCT TGCTACAGCCTGTAGGATGAGTTTGACGTGGCCAGCAGCACCATCTGGTCAACCTCATTCCAGAATGGCACAGTCACAAGTGAAGCATGC CACTGTCAAATCCGAGAATGTAAACCGCTGAACAGCTATGGATCAAATGGTAGCCCTCAAAAGATATGTTCATGCCCTAACCCTCAGAAC CTATAAATATTACTTTATTTGGAAAAGAATCTTTGCAGATAGAATTAAGAATTTTGAGATGGGTCATTATGGATCATCCCAGTGAACCTA ATGCCATCACGAGGGTTCTTATCAGAGACAGGTAGAGGGAGATTTGAGTACAGAAGACAAGATATTCGTGTGATGATGCAGACAGAGACT GGAGTGATGCCACCACAAGCCAAGCAATGCCTGGAGCCACCAGGAGCTGGGACAGGCAGGAAGGATTCTCCCTTATACCCCTCAGAGCAA TCTTGGCCCCTCTGACGTCTTGACTTTAGACTTCTGGTCCCCAGAACGGAGAGAGAATAAATCTTTCTTGTTTTAAGGCTCCAACAAATT GGTAGTCACTTGTTACAGCAACCACAGGAAATGTATACAGCTTCTGATACTTCTGAAAACCTCACACAGCCAAAGGGTACATCCTTGGTA TAGAGGCTCACTCTTACTCACCAGCCAGGCAAGGAAGGCTCAATCCTTTGGTGTTAGAGAGATAGATGTTGGGTTTTCAAATTTCAACAT AGAGAAATCAGTCATTTGCAATGCTTTTGAGAAAGTACTGTGTATACCCTACGAGCCTGCACTCCTTATGTGTGAGACTGATGACCATTG GTTGGCTTATTATCCATTCCACTAAGTGACAAAATCCCACTGACTATTCAAATCCAGGCTCCTGGCATGCCTGTACCTTAGAATCACAAC CAGCTGCAATTCCAGGATGGAGTTCAAACTAATTGTGGGGGCATGTGCTTCTTACATGACTGCTAGATTGTTCCCAGATGGGGAAGGTTG >14713_14713_4_CD99-DHRSX_CD99_chrY_2559468_ENST00000381192_DHRSX_chrY_2159644_ENST00000334651_length(amino acids)=270AA_BP=34 MHSGTVPARSGRTMARGAALALLLFGLLGVLVAAPVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGL NYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDP GVVNTDVYKHVFWATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKETKSLHVTYNQKLQQQLWSKSCEMTGVLDVTL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CD99-DHRSX |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CD99-DHRSX |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CD99-DHRSX |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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