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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CDH2-LAMA3 (FusionGDB2 ID:15070)

Fusion Gene Summary for CDH2-LAMA3

check button Fusion gene summary
Fusion gene informationFusion gene name: CDH2-LAMA3
Fusion gene ID: 15070
HgeneTgene
Gene symbol

CDH2

LAMA3

Gene ID

1000

3910

Gene namecadherin 2laminin subunit alpha 4
SynonymsCD325|CDHN|CDw325|NCADCMD1JJ|LAMA3|LAMA4*-1
Cytomap

18q12.1

6q21

Type of geneprotein-codingprotein-coding
Descriptioncadherin-2N-cadherin 1cadherin 2, type 1, N-cadherin (neuronal)calcium-dependent adhesion protein, neuronalneural cadherinlaminin subunit alpha-4laminin alpha 4 chainlaminin, alpha 4
Modification date2020031320200313
UniProtAcc

P19022

Q16787

Ensembl transtripts involved in fusion geneENST00000269141, ENST00000399380, 
ENST00000269217, ENST00000587184, 
ENST00000588770, ENST00000313654, 
ENST00000399516, 
Fusion gene scores* DoF score6 X 6 X 4=14420 X 22 X 6=2640
# samples 821
** MAII scorelog2(8/144*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2640*10)=-3.65207669657969
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CDH2 [Title/Abstract] AND LAMA3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCDH2(25727637)-LAMA3(21393021), # samples:2
CDH2(25727637)-LAMA3(21394367), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CDH2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LAMA3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-7669-01ACDH2chr18

25727637

-LAMA3chr18

21393021

+
ChimerDB4LUADTCGA-44-7669-01ACDH2chr18

25727637

-LAMA3chr18

21394367

+


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Fusion Gene ORF analysis for CDH2-LAMA3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000269141ENST00000269217CDH2chr18

25727637

-LAMA3chr18

21393021

+
5CDS-intronENST00000269141ENST00000269217CDH2chr18

25727637

-LAMA3chr18

21394367

+
5CDS-intronENST00000269141ENST00000587184CDH2chr18

25727637

-LAMA3chr18

21393021

+
5CDS-intronENST00000269141ENST00000587184CDH2chr18

25727637

-LAMA3chr18

21394367

+
5CDS-intronENST00000269141ENST00000588770CDH2chr18

25727637

-LAMA3chr18

21393021

+
5CDS-intronENST00000269141ENST00000588770CDH2chr18

25727637

-LAMA3chr18

21394367

+
Frame-shiftENST00000269141ENST00000313654CDH2chr18

25727637

-LAMA3chr18

21394367

+
Frame-shiftENST00000269141ENST00000399516CDH2chr18

25727637

-LAMA3chr18

21394367

+
In-frameENST00000269141ENST00000313654CDH2chr18

25727637

-LAMA3chr18

21393021

+
In-frameENST00000269141ENST00000399516CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-3CDSENST00000399380ENST00000313654CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-3CDSENST00000399380ENST00000313654CDH2chr18

25727637

-LAMA3chr18

21394367

+
intron-3CDSENST00000399380ENST00000399516CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-3CDSENST00000399380ENST00000399516CDH2chr18

25727637

-LAMA3chr18

21394367

+
intron-intronENST00000399380ENST00000269217CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-intronENST00000399380ENST00000269217CDH2chr18

25727637

-LAMA3chr18

21394367

+
intron-intronENST00000399380ENST00000587184CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-intronENST00000399380ENST00000587184CDH2chr18

25727637

-LAMA3chr18

21394367

+
intron-intronENST00000399380ENST00000588770CDH2chr18

25727637

-LAMA3chr18

21393021

+
intron-intronENST00000399380ENST00000588770CDH2chr18

25727637

-LAMA3chr18

21394367

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000269141CDH2chr1825727637-ENST00000313654LAMA3chr1821393021+92755962588562943
ENST00000269141CDH2chr1825727637-ENST00000399516LAMA3chr1821393021+86895962586882888

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000269141ENST00000313654CDH2chr1825727637-LAMA3chr1821393021+0.0005033590.9994966
ENST00000269141ENST00000399516CDH2chr1825727637-LAMA3chr1821393021+0.0006654090.9993345

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Fusion Genomic Features for CDH2-LAMA3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CDH2chr1825727636-LAMA3chr1821393020+0.0005781830.99942183
CDH2chr1825727636-LAMA3chr1821394366+3.21E-060.9999968
CDH2chr1825727636-LAMA3chr1821393020+0.0005781830.99942183
CDH2chr1825727636-LAMA3chr1821394366+3.21E-060.9999968

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CDH2-LAMA3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:25727637/chr18:21393021)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CDH2

P19022

LAMA3

Q16787

FUNCTION: Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. {ECO:0000250|UniProtKB:P15116}.FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.; FUNCTION: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751852_19415803334.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751987_21695803334.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752322_23885803334.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741852_19415803278.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741987_21695803278.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742322_23885803278.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371852_194101669.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371987_216901669.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372322_238801669.0Coiled coilOntology_term=ECO:0000255
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751266_13115803334.0DomainLaminin EGF-like 9
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751312_13555803334.0DomainLaminin EGF-like 10
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751356_14045803334.0DomainLaminin EGF-like 11
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751405_14555803334.0DomainLaminin EGF-like 12
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751476_16535803334.0DomainLaminin IV type A
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751687_17335803334.0DomainLaminin EGF-like 13
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751734_17865803334.0DomainLaminin EGF-like 14
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751787_18215803334.0DomainLaminin EGF-like 15%3B truncated
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752390_25915803334.0DomainLaminin G-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752598_27605803334.0DomainLaminin G-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752767_29275803334.0DomainLaminin G-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752986_31505803334.0DomainLaminin G-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412753157_33305803334.0DomainLaminin G-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275590_6305803334.0DomainLaminin EGF-like 6
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275631_6835803334.0DomainLaminin EGF-like 7
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275684_7285803334.0DomainLaminin EGF-like 8
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741266_13115803278.0DomainLaminin EGF-like 9
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741312_13555803278.0DomainLaminin EGF-like 10
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741356_14045803278.0DomainLaminin EGF-like 11
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741405_14555803278.0DomainLaminin EGF-like 12
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741476_16535803278.0DomainLaminin IV type A
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741687_17335803278.0DomainLaminin EGF-like 13
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741734_17865803278.0DomainLaminin EGF-like 14
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741787_18215803278.0DomainLaminin EGF-like 15%3B truncated
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742390_25915803278.0DomainLaminin G-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742598_27605803278.0DomainLaminin G-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742767_29275803278.0DomainLaminin G-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742986_31505803278.0DomainLaminin G-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612743157_33305803278.0DomainLaminin G-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274590_6305803278.0DomainLaminin EGF-like 6
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274631_6835803278.0DomainLaminin EGF-like 7
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274684_7285803278.0DomainLaminin EGF-like 8
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371266_131101669.0DomainLaminin EGF-like 9
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371312_135501669.0DomainLaminin EGF-like 10
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371356_140401669.0DomainLaminin EGF-like 11
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371405_145501669.0DomainLaminin EGF-like 12
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371476_165301669.0DomainLaminin IV type A
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371687_173301669.0DomainLaminin EGF-like 13
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371734_178601669.0DomainLaminin EGF-like 14
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371787_182101669.0DomainLaminin EGF-like 15%3B truncated
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372390_259101669.0DomainLaminin G-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372598_276001669.0DomainLaminin G-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372767_292701669.0DomainLaminin G-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372986_315001669.0DomainLaminin G-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037299_35501669.0DomainLaminin EGF-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840373157_333001669.0DomainLaminin G-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037356_42501669.0DomainLaminin EGF-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037426_46901669.0DomainLaminin EGF-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST0000058718403743_29801669.0DomainLaminin N-terminal
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037491_53501669.0DomainLaminin EGF-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037536_58801669.0DomainLaminin EGF-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037590_63001669.0DomainLaminin EGF-like 6
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037631_68301669.0DomainLaminin EGF-like 7
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037684_72801669.0DomainLaminin EGF-like 8
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412752278_22805803334.0MotifCell attachment site
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612742278_22805803278.0MotifCell attachment site
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840372278_228001669.0MotifCell attachment site
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751266_14655803334.0RegionNote=Domain III B
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751654_18215803334.0RegionNote=Domain III A
TgeneLAMA3chr18:25727637chr18:21393021ENST0000031365412751822_23895803334.0RegionNote=Domain II and I
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275796_12655803334.0RegionNote=Domain IV 1 (domain IV B)
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741266_14655803278.0RegionNote=Domain III B
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741654_18215803278.0RegionNote=Domain III A
TgeneLAMA3chr18:25727637chr18:21393021ENST0000039951612741822_23895803278.0RegionNote=Domain II and I
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274796_12655803278.0RegionNote=Domain IV 1 (domain IV B)
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371266_146501669.0RegionNote=Domain III B
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371654_182101669.0RegionNote=Domain III A
TgeneLAMA3chr18:25727637chr18:21393021ENST000005871840371822_238901669.0RegionNote=Domain II and I
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037298_72801669.0RegionNote=Domain V
TgeneLAMA3chr18:25727637chr18:21393021ENST00000587184037796_126501669.0RegionNote=Domain IV 1 (domain IV B)

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216863_87857907.0Compositional biasNote=Ser-rich
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216160_26757907.0DomainCadherin 1
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216268_38257907.0DomainCadherin 2
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216383_49757907.0DomainCadherin 3
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216498_60357907.0DomainCadherin 4
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216604_71457907.0DomainCadherin 5
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216160_72457907.0Topological domainExtracellular
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216746_90657907.0Topological domainCytoplasmic
HgeneCDH2chr18:25727637chr18:21393021ENST00000269141-216725_74557907.0TransmembraneHelical
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275299_3555803334.0DomainLaminin EGF-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275356_4255803334.0DomainLaminin EGF-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275426_4695803334.0DomainLaminin EGF-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST00000313654127543_2985803334.0DomainLaminin N-terminal
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275491_5355803334.0DomainLaminin EGF-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275536_5885803334.0DomainLaminin EGF-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274299_3555803278.0DomainLaminin EGF-like 1
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274356_4255803278.0DomainLaminin EGF-like 2
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274426_4695803278.0DomainLaminin EGF-like 3
TgeneLAMA3chr18:25727637chr18:21393021ENST00000399516127443_2985803278.0DomainLaminin N-terminal
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274491_5355803278.0DomainLaminin EGF-like 4
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274536_5885803278.0DomainLaminin EGF-like 5
TgeneLAMA3chr18:25727637chr18:21393021ENST000003136541275298_7285803334.0RegionNote=Domain V
TgeneLAMA3chr18:25727637chr18:21393021ENST000003995161274298_7285803278.0RegionNote=Domain V


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Fusion Gene Sequence for CDH2-LAMA3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>15070_15070_1_CDH2-LAMA3_CDH2_chr18_25727637_ENST00000269141_LAMA3_chr18_21393021_ENST00000313654_length(transcript)=9275nt_BP=596nt
CCTCCACCGGCCAAGGTCCCCGCCGCTGCATCCCTCGCGGCTTCCGCTGCGCTCCGGGCCGGAGCCGAGCCGCCTGCGCTGCCACAGCAG
CCGCCTCCACACACTCGCAGACGCTCACACGCTCTCCCTCCCTGTTCCCCCGCCCCCTCCCCAGCTCCTTGATCTCTGGGTCTGTTTTAT
TACTCCTGGTGCGAGTCCCGCGGACTCCGCGGCCCGCTATTTGTCATCAGCTCGCTCTCCATTGGCGGGGAGCGGAGAGCAGCGAAGAAG
GGGGTGGGGAGGGGAGGGGAAGGGAAGGGGGTGGAAACTGCCTGGAGCCGTTTCTCCGCGCCGCTGTTGGTGCTGCCGCTGCCTCCTCCT
CCTCCGCCGCCGCCGCCGCCGCCGCCGCCTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGCTGCG
GACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTGAAATCGCATTATGCAAGACTGGATTTCCTGAAGA
TGTTTACAGTGCAGTCTTATCGAAGGATGTGCATGAAGGACAGCCTCTTCTCAATGGTTCCAGCAGTGCTTGTGACCCAGCTGGTACCAT
CAACTCCAATTTGGGGTATTGCCAATGCAAGCTTCATGTTGAAGGTCCTACTTGTAGCCGCTGCAAACTGTTATATTGGAATCTGGACAA
AGAAAACCCCAGTGGATGTTCAGAATGCAAGTGCCATAAGGCGGGAACAGTGAGTGGAACTGGAGAGTGTAGGCAGGGAGATGGTGACTG
TCACTGCAAGTCCCATGTGGGTGGCGATTCCTGCGACACCTGTGAAGATGGATATTTTGCTTTGGAAAAGAGCAATTACTTTGGGTGTCA
AGGGTGTCAGTGTGACATTGGTGGGGCATTGTCCTCCATGTGCAGTGGGCCCTCGGGAGTGTGCCAGTGCCGAGAGCATGTCGTGGGAAA
GGTGTGCCAGCGGCCTGAAAACAACTACTATTTCCCAGATTTGCATCATATGAAGTATGAGATTGAAGACGGCAGCACACCTAATGGGAG
AGACCTTCGATTTGGATTTGATCCGCTGGCATTTCCTGAGTTTAGCTGGAGAGGATATGCCCAAATGACCTCAGTACAGAATGATGTAAG
AATAACATTGAATGTAGGGAAGTCAAGTGGCTCCTTGTTTCGTGTTATTCTGAGATACGTTAACCCTGGAACTGAAGCAGTATCTGGCCA
TATAACTATTTATCCATCCTGGGGTGCTGCTCAAAGCAAAGAGATCATCTTCCTGCCGAGTAAGGAGCCAGCCTTTGTCACTGTCCCTGG
AAATGGTTTTGCAGACCCATTTTCAATCACACCAGGAATATGGGTTGCTTGTATTAAGGCAGAAGGAGTCCTTCTGGATTACCTGGTGCT
GCTCCCCAGGGACTACTATGAAGCCTCTGTACTGCAGCTGCCAGTCACAGAACCATGTGCCTACGCAGGACCTCCCCAAGAAAATTGCTT
ACTCTACCAGCATTTGCCAGTGACCAGATTCCCCTGTACCCTGGCTTGTGAGGCCAGACACTTCCTGCTTGATGGGGAGCCAAGACCCGT
GGCAGTGAGGCAGCCCACACCTGCACACCCTGTCATGGTGGACCTCAGCGGGAGAGAGGTGGAATTGCATCTGCGGCTGCGCATCCCACA
GGTTGGCCACTACGTGGTTGTGGTCGAGTATTCCACGGAGGCAGCTCAGCTGTTTGTGGTTGATGTGAATGTGAAGAGCTCCGGGTCTGT
TCTGGCAGGCCAGGTGAACATTTACAGCTGCAACTACAGTGTTCTCTGCCGGAGTGCTGTGATTGATCACATGAGCCGCATCGCCATGTA
TGAGCTATTGGCAGATGCAGACATTCAGCTCAAGGGACACATGGCCCGATTCCTTCTGCATCAAGTTTGTATCATACCTATTGAAGAATT
CTCAGCTGAGTATGTGAGACCACAAGTCCACTGCATTGCCAGTTATGGGCGATTTGTCAATCAAAGTGCCACCTGTGTCTCCTTGGCCCA
TGAAACTCCTCCAACAGCATTAATTTTGGATGTTCTAAGTGGCAGGCCTTTCCCTCACCTGCCCCAGCAGTCGTCACCTTCTGTTGATGT
TCTTCCTGGGGTCACCTTGAAGGCACCGCAGAATCAAGTGACCCTGAGAGGACGTGTACCACACCTGGGCCGATACGTCTTTGTCATCCA
TTTTTACCAAGCAGCGCACCCGACGTTTCCCGCGCAGGTGTCGGTGGATGGCGGGTGGCCACGGGCAGGCTCCTTCCATGCCTCTTTTTG
CCCCCATGTGCTTGGCTGCCGGGATCAAGTGATTGCCGAAGGCCAGATTGAGTTTGACATCTCAGAGCCTGAAGTGGCCGCAACTGTGAA
GGTTCCAGAAGGAAAGTCCTTGGTTTTGGTCCGTGTTCTAGTGGTGCCTGCAGAAAACTATGACTACCAAATACTTCACAAAAAATCCAT
GGACAAGTCACTCGAGTTTATCACCAATTGTGGAAAAAACAGCTTTTACCTTGACCCCCAGACAGCCTCCAGATTCTGTAAGAATTCCGC
CAGGTCCCTGGTGGCCTTTTACCACAAGGGCGCCCTGCCTTGTGAGTGCCACCCCACTGGGGCCACCGGCCCTCACTGCAGCCCTGAGGG
TGGGCAGTGCCCATGCCAGCCCAACGTCATCGGGCGGCAGTGCACCCGCTGTGCAACAGGCCACTACGGATTCCCACGCTGCAAGCCGTG
CAGCTGTGGTCGGCGCCTTTGTGAAGAGATGACGGGGCAGTGCCGCTGCCCTCCCCGCACGGTCAGGCCCCAGTGTGAGGTGTGTGAGAC
ACACTCATTCAGCTTCCACCCCATGGCCGGCTGCGAAGGCTGCAACTGTTCCAGGAGGGGCACCATCGAGGCTGCCATGCCGGAGTGTGA
CCGGGACAGCGGGCAGTGCAGATGCAAGCCCAGAATCACAGGGCGGCAGTGTGACCGATGTGCTTCCGGGTTTTACCGCTTTCCTGAGTG
TGTTCCCTGCAATTGCAACAGAGATGGGACTGAGCCAGGAGTGTGTGACCCAGGGACCGGGGCTTGCCTCTGCAAGGAAAATGTAGAAGG
CACAGAGTGTAATGTGTGTCGAGAAGGCTCATTCCATTTGGACCCAGCCAATCTCAAGGGTTGTACCAGCTGTTTCTGTTTTGGAGTAAA
TAATCAATGTCACAGCTCACATAAGCGAAGGACTAAGTTTGTGGATATGCTGGGCTGGCACCTGGAGACAGCAGACAGAGTGGACATCCC
TGTCTCTTTCAACCCAGGCAGCAACAGTATGGTGGCGGATCTCCAGGAGCTGCCCGCAACCATCCACAGCGCGTCCTGGGTCGCACCCAC
CTCCTACCTGGGGGACAAGGTTTCTTCATATGGTGGTTACCTCACTTACCAAGCCAAGTCCTTTGGCTTGCCTGGCGACATGGTTCTTCT
GGAAAAGAAGCCGGATGTACAGCTCACTGGTCAGCACATGTCCATCATCTATGAGGAGACAAACACCCCACGGCCAGACCGGCTGCATCA
TGGACGAGTGCACGTGGTCGAGGGAAACTTCAGACATGCCAGCAGCCGTGCCCCAGTGTCTAGGGAGGAGCTGATGACAGTGCTGTCTAG
ACTGGCAGATGTGCGCATCCAAGGCCTCTACTTCACAGAGACTCAAAGGCTCACCCTGAGCGAGGTGGGGCTAGAGGAAGCCTCTGACAC
AGGAAGTGGGCGCATAGCACTTGCTGTGGAAATCTGTGCCTGCCCCCCTGCCTACGCTGGTGACTCTTGTCAGGGTTGTAGCCCTGGATA
CTATCGGGATCATAAAGGCTTGTATACCGGACGGTGTGTTCCCTGCAATTGCAACGGACATTCAAATCAATGCCAGGATGGCTCAGGCAT
ATGTGTTAACTGTCAGCACAACACCGCGGGAGAGCACTGTGAACGCTGCCAGGAGGGCTACTATGGCAACGCCGTCCACGGATCCTGCAG
GGCCTGCCCATGTCCTCACACTAACAGCTTTGCCACTGGCTGTGTGGTGAATGGGGGAGACGTGCGGTGCTCCTGCAAAGCTGGGTACAC
AGGAACACAGTGTGAAAGGTGTGCACCGGGATATTTCGGGAATCCCCAGAAATTCGGAGGTAGCTGCCAACCATGCAGTTGTAACAGCAA
TGGCCAGCTGGGCAGCTGTCATCCCCTGACTGGAGACTGCATAAACCAAGAACCCAAAGATAGCAGCCCTGCAGAAGAATGTGATGATTG
CGACAGCTGTGTGATGACCCTCCTGAACGACCTGGCCACCATGGGCGAGCAGCTCCGCCTGGTCAAGTCTCAGCTGCAGGGCCTGAGTGC
CAGCGCAGGGCTTCTGGAGCAGATGAGGCACATGGAGACCCAGGCCAAGGACCTGAGGAATCAGTTGCTCAACTACCGTTCTGCCATTTC
AAATCATGGATCAAAAATAGAAGGCCTGGAAAGAGAACTGACTGATTTGAATCAAGAATTTGAGACTTTGCAAGAAAAGGCTCAAGTAAA
TTCCAGAAAAGCACAAACATTAAACAACAATGTTAATCGGGCAACACAAAGCGCAAAAGAACTGGATGTGAAGATTAAAAATGTCATCCG
GAATGTGCACATTCTTTTAAAGCAGATCTCTGGGACAGATGGAGAGGGAAACAACGTGCCTTCAGGTGACTTTTCCAGAGAGTGGGCTGA
AGCCCAGCGCATGATGAGGGAACTGCGGAACAGGAACTTTGGAAAGCACCTCAGAGAAGCAGAAGCTGATAAAAGGGAGTCGCAGCTCTT
GCTGAACCGGATAAGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCTTGCTAACAGTATCCGGGATTCTTTAAATGAATACGA
AGCCAAACTCAGTGACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAAGCAGGCAAATGGCTTGAACCAAGAAAACGAGAGAGC
TTTGGGAGCCATTCAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTTCACCAAGTATCTAACCACTGCAGACTCATCTTTGTT
GCAAACCAACATTGCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAAATTAGCTGCCAGTTTAAATGAAGCAAGACAAGAACT
AAGTGACAAAGTAAGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGAGGAGGCAGAAAAGCACGCGCGGTCCTTACAAGAGCT
GGCAAAGCAGCTGGAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCGCTGTGCTGTGGATGCCGCCACCGCCTACGAGAACAT
CCTCAATGCCATCAAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATCTGAATCTGCCCTCCAGACAGTGATAAAGGAAGATCT
GCCAAGAAAAGCTAAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGCCAAGATGACACAAAAGAAGCTAAAGCAAGAAGTCAG
TCCAGCTCTCAACAACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGAAGTGATAGACACCAATCTCACAACTCTCCGAGATGG
TCTTCATGGGATACAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAGCATGGTCAGAAAGGCCAACGACATCACAGATGAGGT
TCTGGATGGGCTCAACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTATGGGAGGACACAGAACGAAGACTTCAAAAAGGCTCT
GACTGATGCAGATAACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTGGCGCAAGATTGAAAGTATCAACCAACAGCTGTTGCC
CTTGGGAAACATCTCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGCCAGAGATGCTGCCAGTAAGGTTGCTGTCCCCATGAG
GTTCAATGGTAAATCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTTGAAAGGATATACATCTCTGTCCTTGTTTCTCCAAAG
GCCCAACTCAAGAGAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGGAAATAAAGATGCCTCCCGGGACTACATCGGCATGGC
AGTTGTGGATGGCCAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGAACTCCAAGTGGACCAGATCTTGACCAAGAGTGAGAC
TAAGGAGGCAGTTATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAGGCTTAATTACACCAAAGGAGCCACATCCAGTAAACC
AGAAACACCCGGAGTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAATTTGGATCCTGAAAATGTTGTATTTTATGTTGGAGG
TTACCCACCTGATTTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGGTTGTATTGAATTAGATGACCTCAATGAAAATGTTCT
GAGCTTGTACAACTTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCCTTGTAGAAGGAGGAAGGAAGAGTCAGACAAAAATTA
TTTTGAAGGTACGGGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCCAACCTTTGGACAGACAATTCAGACCACCGTGGATAG
AGGCTTGCTGTTCTTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGAAGATGGCAAGCTCATGGTGAGATACAAACTGAATTC
AGAGCTACCAAAAGAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCATTCGATTCAGATCAAAATTGGAAAACTCCAAAAGCG
TATGTGGATAAATGTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGATTTCAGCACATATTATCTGGGAGGAATTCCAATTGC
AATCAGGGAAAGATTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAATTTGAAGAAAACCAGTGGTGTCGTTAGATTGAATGA
TACTGTGGGAGTAACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGCCTCATTCTCCAGAGGAGGACAATTGAGTTTCACTGA
TTTGGGCTTACCACCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTTTCAACCCAGTGGCATATTATTAGATCATCAGACATG
GACAAGGAACCTGCAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAGCGATAGCGGCAGCCCAATTTTTAAATCTCCACAGAC
GTATATGGATGGTTTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACTACGGCTTCTCATCGATGACCAGCTTCTGAGAAATAG
CAAAAGGCTAAAACACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAGCAATTTTGAGGGTTGTATTAGCAATGTTTTTGTCCA
GAGGTTATCACTGAGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAGAGATGTGTCCCTGGGAGGCTGCAGTTTAAACAAACC
ACCTTTTCTAATGTTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTTTCGTATCAACCAGCTGTTGCAGGACACACCAGTGGC
CTCCCCAAGGAGCGTGAAGGTGTGGCAAGATGCTTGCTCACCACTTCCCAAGACCCAGGCCAATCATGGAGCCCTCCAGTTTGGGGACAT
TCCCACCAGCCACTTGCTATTCAAGCTTCCTCAGGAGCTGCTGAAACCCAGGTCACAGTTTGCTGTGGACATGCAGACAACATCCTCCAG
AGGACTGGTGTTTCACACGGGCACTAAGAACTCCTTTATGGCTCTTTATCTTTCAAAAGGACGTCTGGTCTTTGCACTGGGGACAGATGG
GAAAAAATTGAGGATCAAAAGCAAGGAGAAATGCAATGATGGGAAATGGCACACGGTGGTGTTTGGCCATGATGGGGAAAAGGGGCGCTT
GGTTGTGGATGGACTGAGGGCCCGGGAGGGAAGTTTGCCTGGAAACTCCACCATCAGCATCAGAGCGCCAGTTTACCTGGGATCACCTCC
ATCAGGGAAACCAAAGAGCCTCCCCACAAACAGCTTTGTGGGATGCCTGAAGAACTTTCAGCTGGATTCAAAACCCTTGTATACCCCTTC
TTCAAGCTTCGGGGTGTCTTCCTGCTTGGGTGGTCCTTTGGAGAAAGGCATTTATTTCTCTGAAGAAGGAGGTCATGTCGTCTTGGCTCA
CTCTGTATTGTTGGGGCCAGAATTTAAGCTTGTTTTCAGCATCCGCCCAAGAAGTCTCACTGGGATCCTAATACACATCGGAAGTCAGCC
CGGGAAGCACTTATGTGTTTACCTGGAGGCAGGAAAGGTCACGGCCTCTATGGACAGTGGGGCAGGTGGGACCTCAACGTCGGTCACACC
AAAGCAGTCTCTGTGTGATGGACAGTGGCACTCGGTGGCAGTCACCATAAAACAACACATCCTGCACCTGGAACTGGACACAGACAGTAG
CTACACAGCTGGACAGATCCCCTTCCCACCTGCCAGCACTCAAGAGCCACTACACCTTGGAGGTGCTCCAGCCAATTTGACGACACTGAG
GATCCCTGTGTGGAAATCATTCTTTGGCTGTCTGAGGAATATTCATGTCAATCACATCCCTGTCCCTGTCACTGAAGCCTTGGAAGTCCA
GGGGCCTGTCAGTCTGAATGGTTGTCCTGACCAGTAACCCAAGCCTATTTCACAGCAAGGAAATTCACCTTCAAAAGCACTGATTACCCA
ATGCACCTCCCTCCCCAGCTCGAGATCATTCTTCACTCAGGACACAAACCAGACAGGTTTAATAGCGAATCTAATTTTGAATTCTGACCA
TGGATACCCATCACTTTGGCATTCAGTGCTACATGTGTATTTTATATAAAAATCCCATTTCTTGAAGATAAAAAAATTGTTATTCAAATT
GTTATGCACAGAATGTTTTTGGTAATATTAATTTCCACTAAAAAATTAAATGTCTTTTAAGAAACATTCTTTTCCACTTGTTAAAAAAAT
TAAATATATTTTAAAGCACTTTAAGAATATGAAACTTTCATATATGTTAAAGGATTATAATTTATGGAATTAAAAAATGCAGTGTAGTCC

>15070_15070_1_CDH2-LAMA3_CDH2_chr18_25727637_ENST00000269141_LAMA3_chr18_21393021_ENST00000313654_length(amino acids)=2943AA_BP=190
MHPSRLPLRSGPEPSRLRCHSSRLHTLADAHTLSLPVPPPPPQLLDLWVCFITPGASPADSAARYLSSARSPLAGSGEQRRRGWGGEGKG
RGWKLPGAVSPRRCWCCRCLLLLRRRRRRRRLLRLFARPLSASMCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSK
DVHEGQPLLNGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG
DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDP
LAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS
ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQPTPA
HPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI
QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKA
PQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV
LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPN
VIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC
KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHK
RRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL
TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALA
VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN
SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLL
NDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN
NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQ
KTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL
MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAE
DAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGD
IDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNM
DRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC
VYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLP
SRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN
GDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNIS
TPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTL
EDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEV
LDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFK
LPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAR
EGSLPGNSTISIRAPVYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF
KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPF

--------------------------------------------------------------
>15070_15070_2_CDH2-LAMA3_CDH2_chr18_25727637_ENST00000269141_LAMA3_chr18_21393021_ENST00000399516_length(transcript)=8689nt_BP=596nt
CCTCCACCGGCCAAGGTCCCCGCCGCTGCATCCCTCGCGGCTTCCGCTGCGCTCCGGGCCGGAGCCGAGCCGCCTGCGCTGCCACAGCAG
CCGCCTCCACACACTCGCAGACGCTCACACGCTCTCCCTCCCTGTTCCCCCGCCCCCTCCCCAGCTCCTTGATCTCTGGGTCTGTTTTAT
TACTCCTGGTGCGAGTCCCGCGGACTCCGCGGCCCGCTATTTGTCATCAGCTCGCTCTCCATTGGCGGGGAGCGGAGAGCAGCGAAGAAG
GGGGTGGGGAGGGGAGGGGAAGGGAAGGGGGTGGAAACTGCCTGGAGCCGTTTCTCCGCGCCGCTGTTGGTGCTGCCGCTGCCTCCTCCT
CCTCCGCCGCCGCCGCCGCCGCCGCCGCCTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGCTGCG
GACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTGAAATCGCATTATGCAAGACTGGATTTCCTGAAGA
TGTTTACAGTGCAGTCTTATCGAAGGATGTGCATGAAGGACAGCCTCTTCTCAATGGTTCCAGCAGTGCTTGTGACCCAGCTGGTACCAT
CAACTCCAATTTGGGGTATTGCCAATGCAAGCTTCATGTTGAAGGTCCTACTTGTAGCCGCTGCAAACTGTTATATTGGAATCTGGACAA
AGAAAACCCCAGTGGATGTTCAGAATGCAAGTGCCATAAGGCGGGAACAGTGAGTGGAACTGGAGAGTGTAGGCAGGGAGATGGTGACTG
TCACTGCAAGTCCCATGTGGGTGGCGATTCCTGCGACACCTGTGAAGATGGATATTTTGCTTTGGAAAAGAGCAATTACTTTGGGTGTCA
AGGGTGTCAGTGTGACATTGGTGGGGCATTGTCCTCCATGTGCAGTGGGCCCTCGGGAGTGTGCCAGTGCCGAGAGCATGTCGTGGGAAA
GGTGTGCCAGCGGCCTGAAAACAACTACTATTTCCCAGATTTGCATCATATGAAGTATGAGATTGAAGACGGCAGCACACCTAATGGGAG
AGACCTTCGATTTGGATTTGATCCGCTGGCATTTCCTGAGTTTAGCTGGAGAGGATATGCCCAAATGACCTCAGTACAGAATGATGTAAG
AATAACATTGAATGTAGGGAAGTCAAGTGGCTCCTTGTTTCGTGTTATTCTGAGATACGTTAACCCTGGAACTGAAGCAGTATCTGGCCA
TATAACTATTTATCCATCCTGGGGTGCTGCTCAAAGCAAAGAGATCATCTTCCTGCCGAGTAAGGAGCCAGCCTTTGTCACTGTCCCTGG
AAATGGTTTTGCAGACCCATTTTCAATCACACCAGGAATATGGGTTGCTTGTATTAAGGCAGAAGGAGTCCTTCTGGATTACCTGGTGCT
GCTCCCCAGGGACTACTATGAAGCCTCTGTACTGCAGCTGCCAGTCACAGAACCATGTGCCTACGCAGGACCTCCCCAAGAAAATTGCTT
ACTCTACCAGCATTTGCCAGTGACCAGATTCCCCTGTACCCTGGCTTGTGAGGCCAGACACTTCCTGCTTGATGGGGAGCCAAGACCCGT
GGCAGTGAGGCAGCCCACACCTGCACACCCTGTCATGGTGGACCTCAGCGGGAGAGAGGTGGAATTGCATCTGCGGCTGCGCATCCCACA
GGTTGGCCACTACGTGGTTGTGGTCGAGTATTCCACGGAGGCAGCTCAGCTGTTTGTGGTTGATGTGAATGTGAAGAGCTCCGGGTCTGT
TCTGGCAGGCCAGGTGAACATTTACAGCTGCAACTACAGTGTTCTCTGCCGGAGTGCTGTGATTGATCACATGAGCCGCATCGCCATGTA
TGAGCTATTGGCAGATGCAGACATTCAGCTCAAGGGACACATGGCCCGATTCCTTCTGCATCAAGTTTGTATCATACCTATTGAAGAATT
CTCAGCTGAGTATGTGAGACCACAAGTCCACTGCATTGCCAGTTATGGGCGATTTGTCAATCAAAGTGCCACCTGTGTCTCCTTGGCCCA
TGAAACTCCTCCAACAGCATTAATTTTGGATGTTCTAAGTGGCAGGCCTTTCCCTCACCTGCCCCAGCAGTCGTCACCTTCTGTTGATGT
TCTTCCTGGGGTCACCTTGAAGGCACCGCAGAATCAAGTGACCCTGAGAGGACGTGTACCACACCTGGGCCGATACGTCTTTGTCATCCA
TTTTTACCAAGCAGCGCACCCGACGTTTCCCGCGCAGGTGTCGGTGGATGGCGGGTGGCCACGGGCAGGCTCCTTCCATGCCTCTTTTTG
CCCCCATGTGCTTGGCTGCCGGGATCAAGTGATTGCCGAAGGCCAGATTGAGTTTGACATCTCAGAGCCTGAAGTGGCCGCAACTGTGAA
GGTTCCAGAAGGAAAGTCCTTGGTTTTGGTCCGTGTTCTAGTGGTGCCTGCAGAAAACTATGACTACCAAATACTTCACAAAAAATCCAT
GGACAAGTCACTCGAGTTTATCACCAATTGTGGAAAAAACAGCTTTTACCTTGACCCCCAGACAGCCTCCAGATTCTGTAAGAATTCCGC
CAGGTCCCTGGTGGCCTTTTACCACAAGGGCGCCCTGCCTTGTGAGTGCCACCCCACTGGGGCCACCGGCCCTCACTGCAGCCCTGAGGG
TGGGCAGTGCCCATGCCAGCCCAACGTCATCGGGCGGCAGTGCACCCGCTGTGCAACAGGCCACTACGGATTCCCACGCTGCAAGCCGTG
CAGCTGTGGTCGGCGCCTTTGTGAAGAGATGACGGGGCAGTGCCGCTGCCCTCCCCGCACGGTCAGGCCCCAGTGTGAGGTGTGTGAGAC
ACACTCATTCAGCTTCCACCCCATGGCCGGCTGCGAAGGCTGCAACTGTTCCAGGAGGGGCACCATCGAGGCTGCCATGCCGGAGTGTGA
CCGGGACAGCGGGCAGTGCAGATGCAAGCCCAGAATCACAGGGCGGCAGTGTGACCGATGTGCTTCCGGGTTTTACCGCTTTCCTGAGTG
TGTTCCCTGCAATTGCAACAGAGATGGGACTGAGCCAGGAGTGTGTGACCCAGGGACCGGGGCTTGCCTCTGCAAGGAAAATGTAGAAGG
CACAGAGTGTAATGTGTGTCGAGAAGGCTCATTCCATTTGGACCCAGCCAATCTCAAGGGTTGTACCAGCTGTTTCTGTTTTGGAGTAAA
TAATCAATGTCACAGCTCACATAAGCGAAGGACTAAGTTTGTGGATATGCTGGGCTGGCACCTGGAGACAGCAGACAGAGTGGACATCCC
TGTCTCTTTCAACCCAGGCAGCAACAGTATGGTGGCGGATCTCCAGGAGCTGCCCGCAACCATCCACAGCGCGTCCTGGGTCGCACCCAC
CTCCTACCTGGGGGACAAGGTTTCTTCATATGGTGGTTACCTCACTTACCAAGCCAAGTCCTTTGGCTTGCCTGGCGACATGGTTCTTCT
GGAAAAGAAGCCGGATGTACAGCTCACTGGTCAGCACATGTCCATCATCTATGAGGAGACAAACACCCCACGGCCAGACCGGCTGCATCA
TGGACGAGTGCACGTGGTCGAGGGAAACTTCAGACATGCCAGCAGCCGTGCCCCAGTGTCTAGGGAGGAGCTGATGACAGTGCTGTCTAG
ACTGGCAGATGTGCGCATCCAAGGCCTCTACTTCACAGAGACTCAAAGGCTCACCCTGAGCGAGGTGGGGCTAGAGGAAGCCTCTGACAC
AGGAAGTGGGCGCATAGCACTTGCTGTGGAAATCTGTGCCTGCCCCCCTGCCTACGCTGGTGACTCTTGTCAGGGTTGTAGCCCTGGATA
CTATCGGGATCATAAAGGCTTGTATACCGGACGGTGTGTTCCCTGCAATTGCAACGGACATTCAAATCAATGCCAGGATGGCTCAGGCAT
ATGTGTTAACTGTCAGCACAACACCGCGGGAGAGCACTGTGAACGCTGCCAGGAGGGCTACTATGGCAACGCCGTCCACGGATCCTGCAG
GGCCTGCCCATGTCCTCACACTAACAGCTTTGCCACTGGCTGTGTGGTGAATGGGGGAGACGTGCGGTGCTCCTGCAAAGCTGGGTACAC
AGGAACACAGTGTGAAAGGTGTGCACCGGGATATTTCGGGAATCCCCAGAAATTCGGAGGTAGCTGCCAACCATGCAGTTGTAACAGCAA
TGGCCAGCTGGGCAGCTGTCATCCCCTGACTGGAGACTGCATAAACCAAGAACCCAAAGATAGCAGCCCTGCAGAAGAATGTGATGATTG
CGACAGCTGTGTGATGACCCTCCTGAACGACCTGGCCACCATGGGCGAGCAGCTCCGCCTGGTCAAGTCTCAGCTGCAGGGCCTGAGTGC
CAGCGCAGGGCTTCTGGAGCAGATGAGGCACATGGAGACCCAGGCCAAGGACCTGAGGAATCAGTTGCTCAACTACCGTTCTGCCATTTC
AAATCATGGATCAAAAATAGAAGGCCTGGAAAGAGAACTGACTGATTTGAATCAAGAATTTGAGACTTTGCAAGAAAAGGCTCAAGTAAA
TTCCAGAAAAGCACAAACATTAAACAACAATGTTAATCGGGCAACACAAAGCGCAAAAGAACTGGATGTGAAGATTAAAAATGTCATCCG
GAATGTGCACATGCTGAACCGGATAAGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCTTGCTAACAGTATCCGGGATTCTTT
AAATGAATACGAAGCCAAACTCAGTGACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAAGCAGGCAAATGGCTTGAACCAAGA
AAACGAGAGAGCTTTGGGAGCCATTCAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTTCACCAAGTATCTAACCACTGCAGA
CTCATCTTTGTTGCAAACCAACATTGCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAAATTAGCTGCCAGTTTAAATGAAGC
AAGACAAGAACTAAGTGACAAAGTAAGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGAGGAGGCAGAAAAGCACGCGCGGTC
CTTACAAGAGCTGGCAAAGCAGCTGGAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCGCTGTGCTGTGGATGCCGCCACCGC
CTACGAGAACATCCTCAATGCCATCAAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATCTGAATCTGCCCTCCAGACAGTGAT
AAAGGAAGATCTGCCAAGAAAAGCTAAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGCCAAGATGACACAAAAGAAGCTAAA
GCAAGAAGTCAGTCCAGCTCTCAACAACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGAAGTGATAGACACCAATCTCACAAC
TCTCCGAGATGGTCTTCATGGGATACAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAGCATGGTCAGAAAGGCCAACGACAT
CACAGATGAGGTTCTGGATGGGCTCAACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTATGGGAGGACACAGAACGAAGACTT
CAAAAAGGCTCTGACTGATGCAGATAACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTGGCGCAAGATTGAAAGTATCAACCA
ACAGCTGTTGCCCTTGGGAAACATCTCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGCCAGAGATGCTGCCAGTAAGGTTGC
TGTCCCCATGAGGTTCAATGGTAAATCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTTGAAAGGATATACATCTCTGTCCTT
GTTTCTCCAAAGGCCCAACTCAAGAGAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGGAAATAAAGATGCCTCCCGGGACTA
CATCGGCATGGCAGTTGTGGATGGCCAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGAACTCCAAGTGGACCAGATCTTGAC
CAAGAGTGAGACTAAGGAGGCAGTTATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAGGCTTAATTACACCAAAGGAGCCAC
ATCCAGTAAACCAGAAACACCCGGAGTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAATTTGGATCCTGAAAATGTTGTATT
TTATGTTGGAGGTTACCCACCTGATTTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGGTTGTATTGAATTAGATGACCTCAA
TGAAAATGTTCTGAGCTTGTACAACTTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCCTTGTAGAAGGAGGAAGGAAGAGTC
AGACAAAAATTATTTTGAAGGTACGGGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCCAACCTTTGGACAGACAATTCAGAC
CACCGTGGATAGAGGCTTGCTGTTCTTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGAAGATGGCAAGCTCATGGTGAGATA
CAAACTGAATTCAGAGCTACCAAAAGAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCATTCGATTCAGATCAAAATTGGAAA
ACTCCAAAAGCGTATGTGGATAAATGTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGATTTCAGCACATATTATCTGGGAGG
AATTCCAATTGCAATCAGGGAAAGATTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAATTTGAAGAAAACCAGTGGTGTCGT
TAGATTGAATGATACTGTGGGAGTAACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGCCTCATTCTCCAGAGGAGGACAATT
GAGTTTCACTGATTTGGGCTTACCACCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTTTCAACCCAGTGGCATATTATTAGA
TCATCAGACATGGACAAGGAACCTGCAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAGCGATAGCGGCAGCCCAATTTTTAA
ATCTCCACAGACGTATATGGATGGTTTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACTACGGCTTCTCATCGATGACCAGCT
TCTGAGAAATAGCAAAAGGCTAAAACACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAGCAATTTTGAGGGTTGTATTAGCAA
TGTTTTTGTCCAGAGGTTATCACTGAGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAGAGATGTGTCCCTGGGAGGCTGCAG
TTTAAACAAACCACCTTTTCTAATGTTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTTTCGTATCAACCAGCTGTTGCAGGA
CACACCAGTGGCCTCCCCAAGGAGCGTGAAGGTGTGGCAAGATGCTTGCTCACCACTTCCCAAGACCCAGGCCAATCATGGAGCCCTCCA
GTTTGGGGACATTCCCACCAGCCACTTGCTATTCAAGCTTCCTCAGGAGCTGCTGAAACCCAGGTCACAGTTTGCTGTGGACATGCAGAC
AACATCCTCCAGAGGACTGGTGTTTCACACGGGCACTAAGAACTCCTTTATGGCTCTTTATCTTTCAAAAGGACGTCTGGTCTTTGCACT
GGGGACAGATGGGAAAAAATTGAGGATCAAAAGCAAGGAGAAATGCAATGATGGGAAATGGCACACGGTGGTGTTTGGCCATGATGGGGA
AAAGGGGCGCTTGGTTGTGGATGGACTGAGGGCCCGGGAGGGAAGTTTGCCTGGAAACTCCACCATCAGCATCAGAGCGCCAGTTTACCT
GGGATCACCTCCATCAGGGAAACCAAAGAGCCTCCCCACAAACAGCTTTGTGGGATGCCTGAAGAACTTTCAGCTGGATTCAAAACCCTT
GTATACCCCTTCTTCAAGCTTCGGGGTGTCTTCCTGCTTGGGTGGTCCTTTGGAGAAAGGCATTTATTTCTCTGAAGAAGGAGGTCATGT
CGTCTTGGCTCACTCTGTATTGTTGGGGCCAGAATTTAAGCTTGTTTTCAGCATCCGCCCAAGAAGTCTCACTGGGATCCTAATACACAT
CGGAAGTCAGCCCGGGAAGCACTTATGTGTTTACCTGGAGGCAGGAAAGGTCACGGCCTCTATGGACAGTGGGGCAGGTGGGACCTCAAC
GTCGGTCACACCAAAGCAGTCTCTGTGTGATGGACAGTGGCACTCGGTGGCAGTCACCATAAAACAACACATCCTGCACCTGGAACTGGA
CACAGACAGTAGCTACACAGCTGGACAGATCCCCTTCCCACCTGCCAGCACTCAAGAGCCACTACACCTTGGAGGTGCTCCAGCCAATTT
GACGACACTGAGGATCCCTGTGTGGAAATCATTCTTTGGCTGTCTGAGGAATATTCATGTCAATCACATCCCTGTCCCTGTCACTGAAGC

>15070_15070_2_CDH2-LAMA3_CDH2_chr18_25727637_ENST00000269141_LAMA3_chr18_21393021_ENST00000399516_length(amino acids)=2888AA_BP=190
MHPSRLPLRSGPEPSRLRCHSSRLHTLADAHTLSLPVPPPPPQLLDLWVCFITPGASPADSAARYLSSARSPLAGSGEQRRRGWGGEGKG
RGWKLPGAVSPRRCWCCRCLLLLRRRRRRRRLLRLFARPLSASMCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSK
DVHEGQPLLNGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG
DSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDP
LAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFS
ITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQPTPA
HPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADI
QLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALILDVLSGRPFPHLPQQSSPSVDVLPGVTLKA
PQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLV
LVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPN
VIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC
KPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHK
RRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQL
TGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALA
VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN
SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLL
NDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN
NNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAI
QRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQL
EEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALN
NLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDAD
NSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR
ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPG
VYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGT
GYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWIN
VDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLP
PTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLK
HISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRS
VKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLR
IKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFG
VSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSL
CDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVS

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Fusion Gene PPI Analysis for CDH2-LAMA3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CDH2-LAMA3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CDH2-LAMA3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource