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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ACSM2A-ABCC6 (FusionGDB2 ID:1525) |
Fusion Gene Summary for ACSM2A-ABCC6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ACSM2A-ABCC6 | Fusion gene ID: 1525 | Hgene | Tgene | Gene symbol | ACSM2A | ABCC6 | Gene ID | 123876 | 368 |
| Gene name | acyl-CoA synthetase medium chain family member 2A | ATP binding cassette subfamily C member 6 | |
| Synonyms | A-923A4.1|ACSM2 | ABC34|ARA|EST349056|GACI2|MLP1|MOAT-E|MOATE|MRP6|PXE|PXE1|URG7 | |
| Cytomap | 16p12.3 | 16p13.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | acyl-coenzyme A synthetase ACSM2A, mitochondrialacyl-CoA synthetase medium-chain family member 2benzoate--CoA ligasebutyrate--CoA ligase 2Abutyryl-coenzyme A synthetase 2Amiddle-chain acyl-CoA synthetase 2A | multidrug resistance-associated protein 6URG7 proteinATP-binding cassette, sub-family C (CFTR/MRP), member 6anthracycline resistance-associated proteinmulti-specific organic anion transporter E | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | Q08AH3 | O95255 | |
| Ensembl transtripts involved in fusion gene | ENST00000575558, ENST00000219054, ENST00000396104, ENST00000417235, ENST00000536134, ENST00000573854, ENST00000575690, ENST00000424070, | ENST00000205557, ENST00000574094, ENST00000575728, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ACSM2A [Title/Abstract] AND ABCC6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ACSM2A(20492243)-ABCC6(16263710), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ACSM2A | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process | 19345228 |
| Fusion gene breakpoints across ACSM2A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ABCC6 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | KIRC | TCGA-BP-4801-01A | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
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Fusion Gene ORF analysis for ACSM2A-ABCC6 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000575558 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 3UTR-intron | ENST00000575558 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 3UTR-intron | ENST00000575558 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000219054 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000219054 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000396104 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000396104 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000417235 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000417235 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000536134 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000536134 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000573854 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000573854 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000575690 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| 5CDS-intron | ENST00000575690 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000219054 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000396104 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000417235 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000536134 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000573854 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| In-frame | ENST00000575690 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| intron-3CDS | ENST00000424070 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| intron-intron | ENST00000424070 | ENST00000574094 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| intron-intron | ENST00000424070 | ENST00000575728 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000417235 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4372 | 1442 | 2 | 3166 | 1054 |
| ENST00000536134 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4464 | 1534 | 709 | 3258 | 849 |
| ENST00000573854 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4553 | 1623 | 99 | 3347 | 1082 |
| ENST00000219054 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4580 | 1650 | 135 | 3374 | 1079 |
| ENST00000575690 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4909 | 1979 | 464 | 3703 | 1079 |
| ENST00000396104 | ACSM2A | chr16 | 20492243 | + | ENST00000205557 | ABCC6 | chr16 | 16263710 | - | 4450 | 1520 | 5 | 3244 | 1079 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000417235 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.002385658 | 0.9976144 |
| ENST00000536134 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.004238715 | 0.99576133 |
| ENST00000573854 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.002695883 | 0.9973041 |
| ENST00000219054 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.002889441 | 0.9971105 |
| ENST00000575690 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.003414369 | 0.9965856 |
| ENST00000396104 | ENST00000205557 | ACSM2A | chr16 | 20492243 | + | ABCC6 | chr16 | 16263710 | - | 0.002401659 | 0.99759835 |
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Fusion Genomic Features for ACSM2A-ABCC6 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ACSM2A-ABCC6 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:20492243/chr16:16263710) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ACSM2A | ABCC6 |
| FUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate (By similarity). {ECO:0000250|UniProtKB:Q68CK6}. | FUNCTION: [Isoform 1]: ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Mediates ATP-dependent transport of glutathione conjugates such as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) (in vitro), and an anionic cyclopentapeptide endothelin antagonist, BQ-123 (PubMed:11880368, PubMed:12414644). Does not appear to actively transport drugs outside the cell. Confers low levels of cellular resistance to etoposide, teniposide, anthracyclines and cisplatin (PubMed:12414644). {ECO:0000269|PubMed:11880368, ECO:0000269|PubMed:12414644}.; FUNCTION: [Isoform 1]: Mediates the release of nucleoside triphosphates, predominantly ATP, into the circulation, where it is rapidly converted into AMP and the mineralization inhibitor inorganic pyrophosphate (PPi) by the ecto-enzyme ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), therefore playing a role in PPi homeostasis. {ECO:0000269|PubMed:24277820, ECO:0000269|PubMed:24969777}.; FUNCTION: [Isoform 2]: Inhibits TNF-alpha-mediated apoptosis through blocking one or more caspases. {ECO:0000269|PubMed:23912081}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000219054 | + | 13 | 15 | 221_229 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000219054 | + | 13 | 15 | 359_364 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000396104 | + | 11 | 13 | 221_229 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000396104 | + | 11 | 13 | 359_364 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000573854 | + | 12 | 14 | 221_229 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000573854 | + | 12 | 14 | 359_364 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000575690 | + | 13 | 15 | 221_229 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000575690 | + | 13 | 15 | 359_364 | 503 | 578.0 | Nucleotide binding | ATP |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000219054 | + | 13 | 15 | 469_471 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000396104 | + | 11 | 13 | 469_471 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000573854 | + | 12 | 14 | 469_471 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000575690 | + | 13 | 15 | 469_471 | 503 | 578.0 | Region | Coenzyme A binding |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1265_1499 | 929 | 1504.0 | Domain | ABC transporter 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 947_1228 | 929 | 1504.0 | Domain | ABC transmembrane type-1 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1265_1499 | 0 | 100.0 | Domain | ABC transporter 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 311_593 | 0 | 100.0 | Domain | ABC transmembrane type-1 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 629_853 | 0 | 100.0 | Domain | ABC transporter 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 947_1228 | 0 | 100.0 | Domain | ABC transmembrane type-1 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1299_1306 | 929 | 1504.0 | Nucleotide binding | ATP 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1299_1306 | 0 | 100.0 | Nucleotide binding | ATP 2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 663_670 | 0 | 100.0 | Nucleotide binding | ATP 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1019_1061 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1083_1083 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1105_1175 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1197_1198 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1220_1503 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 961_997 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1019_1061 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1083_1083 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1105_1175 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1197_1198 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 120_131 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1220_1503 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 150_167 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 189_302 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1_31 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 324_349 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 371_426 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 448_450 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 472_533 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 53_72 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 555_575 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 597_939 | 0 | 100.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 94_98 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 961_997 | 0 | 100.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1062_1082 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D14 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1084_1104 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D15 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1176_1196 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D16 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1199_1219 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D17 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 940_960 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D12 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 998_1018 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D13 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1062_1082 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D14 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1084_1104 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D15 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1176_1196 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D16 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 1199_1219 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D17 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 132_149 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D4 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 168_188 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D5 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 303_323 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D6 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 32_52 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 350_370 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D7 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 427_447 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D8 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 451_471 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D9 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 534_554 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D10 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 576_596 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D11 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 73_93 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 940_960 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D12 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 998_1018 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D13 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000575728 | 0 | 2 | 99_119 | 0 | 100.0 | Transmembrane | Helical%3B Name%3D3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000219054 | + | 13 | 15 | 540_542 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000396104 | + | 11 | 13 | 540_542 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000573854 | + | 12 | 14 | 540_542 | 503 | 578.0 | Region | Coenzyme A binding |
| Hgene | ACSM2A | chr16:20492243 | chr16:16263710 | ENST00000575690 | + | 13 | 15 | 540_542 | 503 | 578.0 | Region | Coenzyme A binding |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 311_593 | 929 | 1504.0 | Domain | ABC transmembrane type-1 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 629_853 | 929 | 1504.0 | Domain | ABC transporter 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 663_670 | 929 | 1504.0 | Nucleotide binding | ATP 1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 120_131 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 150_167 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 189_302 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 1_31 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 324_349 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 371_426 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 448_450 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 472_533 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 53_72 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 555_575 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 597_939 | 929 | 1504.0 | Topological domain | Cytoplasmic | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 94_98 | 929 | 1504.0 | Topological domain | Extracellular | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 132_149 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D4 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 168_188 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D5 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 303_323 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D6 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 32_52 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D1 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 350_370 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D7 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 427_447 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D8 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 451_471 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D9 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 534_554 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D10 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 576_596 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D11 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 73_93 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D2 | |
| Tgene | ABCC6 | chr16:20492243 | chr16:16263710 | ENST00000205557 | 20 | 31 | 99_119 | 929 | 1504.0 | Transmembrane | Helical%3B Name%3D3 |
Top |
Fusion Gene Sequence for ACSM2A-ABCC6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >1525_1525_1_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000219054_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4580nt_BP=1650nt GTGCTCTCTTCCAAGGCTGTAGGAGTTCTGGAGCTGCTGGCTGGAGAGGAGGGTGGACGAAGCTCTCTCTAGAAAGACATCCTGAGAGGA CTTGGCAGCCTGCAGATGGCCTATTGTGGGACCTTGTGATCATGCCTGAATATGCATTGGCTGCGAAAAGTTCAGGGACTTTGCACCCTG TGGGGTACTCAGATGTCCAGCCGCACTCTCTACATTAATAGTAGGCAACTGGTGTCCCTGCAGTGGGGCCACCAGGAAGTGCCGGCCAAG TTTAACTTTGCTAGTGATGTGTTGGATCACTGGGCTGACATGGAGAAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAAT GGGAAGGGGAAGGAATTAATGTGGAATTTCAGAGAACTGAGTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTG CAGCGTGGGGATCGTGTGGCAGTGGTGCTGCCCCGAGTGCCTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTT ATGCCTGGAACCATCCAGATGAAATCCACTGACATACTGTATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTC ATCCAAGAAGTGGACACAGTGGCATCTGAATGTCCTTCTCTGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAAC TTCAAGAAACTACTAAATGAGGCATCCACCACTCATCACTGTGTGGAGACTGGAAGCCAGGAAGCATCTGCCATCTACTTCACTAGTGGG ACCAGTGGTCTTCCCAAGATGGCAGAACATTCCTACTCGAGCCTGGGCCTCAAGGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCC TCTGATATAATGTGGACCATATCAGACACAGGTTGGATACTGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACA TTTGTTCATCTCTTGCCAAAGTTTGACCCACTGGTTATTCTAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATT GTTTACCGGATGTTGCTACAGCAGGATCTTTCCAGTTACAAGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCA GAAACTCTGGAGAACTGGAGGGCCCAGACAGGACTGGACATCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCC AAGACAATGAAAATCAAACCAGGATACATGGGAACGGCTGCTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCC CCCGGCACAGAAGGAGACATTGGCATCAGGGTCAAACCCATCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACA GCAGCCAACATTCGAGGAGACTTTTGGCTCCTTGGAGACCGGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAAT GATATCATTAACTCCAGCGGGTACCGGATTGGACCCTCGGAGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTG ATCAGCAGCCCAGACCCCGTCCGAGGAGAGGTGAAGGCCACAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTAC GCACTCTTCCTCTTCCTCTGCCAGCAAGTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGG CAGCAGACGCAGGCAGCCCTGCGTGGCGGGATCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTG CTCCTAGGTGGGGCCCGGGCATCCAGGTTGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACA CCCATTGGTCACCTGCTAAACCGCTTCTCCAAGGAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTAC GCCTTTGGACTCCTGGAGGTCAGCCTGGTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCT GGGTTTCAGAGCCTGTATGTGGTTAGCTCATGCCAGCTGAGACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAG ACGTTCCAGGGCAGCACAGTGGTCCGGGCATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGG ATCAGTTTCCCGCGACTGGTGGCTGACAGGTGGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGT GCTGTGCTGAGCAAAGCCCACCTCAGTGCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTT GTTCGCAACTGGACAGACCTAGAGAACAGCATCGTGTCAGTGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGG CTGCCCACATGTGCAGCTCAGCCCCCCTGGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCG CTGGCTGTGCAGGGCGTGTCCTTCAAGATCCACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCC AGTGGGCTGCTGCGGCTCCAGGAGGCAGCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGC TCCAGGATCAGCATCATCCCCCAGGACCCCATCCTGTTCCCTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAG GCTATCTGGGCAGCCCTGGAGACGGTGCAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGC GAGGACCTGAGCGTGGGCCAGAAACAGCTCCTGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACT GCTGCCGTGGACCCTGGCACGGAGCTGCAGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGC CTGCGCTCCGTGATGGACTGTGCCCGGGTTCTGGTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAG AAGGGCCTGTTTTACAGACTGGCCCAGGAGTCAGGCCTGGTCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCC TGCAGTGCTGGAGATGGAAGTGACCCGTGGTCATCGATAGCTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAAT GGCAGAGAAAGTGGCCAATTATCACAGAGCATCAGAGCCGGAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCT GTCCACCCTGCAGCCAATGTCAACAGCGACTCTCAGCCCCGCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCG GCTAGACCCTTAAATCAGAATCTCTGAGGCTGGGAACTGCCATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCC CAGACTCACATGCAGTTAAAGAAACAATAATATAGAGAGATTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACT CTAGGATAAAGCATCACAGCCAGGGTGTTGACATTGACACAACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGT GTTTATTTTGTCCCATGCAGTTTTATCACACATGTAGGCTCATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCG ACCACACCCATCACTCTCGCTCCTGCCCCCAGTGACCATGCTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTT TTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCC TGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGTGCAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTA TTAGATACGAGGTTTCAGCATATTGGCCAGGCTGGTCTTGAACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGG ATAACAGGCGTGAGCTACCGCACCTGGCCGAGTTTGGTGTATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGA >1525_1525_1_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000219054_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=1079AA_BP=1 MNMHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSE NSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR IKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILN ILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIR ESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRG IKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCR GYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDT VDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQA PFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVE RMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIW IDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLAR -------------------------------------------------------------- >1525_1525_2_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000396104_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4450nt_BP=1520nt CAGGCCTGAATATGCATTGGCTGCGAAAAGTTCAGGGACTTTGCACCCTGTGGGGTACTCAGATGTCCAGCCGCACTCTCTACATTAATA GTAGGCAACTGGTGTCCCTGCAGTGGGGCCACCAGGAAGTGCCGGCCAAGTTTAACTTTGCTAGTGATGTGTTGGATCACTGGGCTGACA TGGAGAAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAATGGGAAGGGGAAGGAATTAATGTGGAATTTCAGAGAACTGA GTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTGCAGCGTGGGGATCGTGTGGCAGTGGTGCTGCCCCGAGTGC CTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTTATGCCTGGAACCATCCAGATGAAATCCACTGACATACTGT ATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTCATCCAAGAAGTGGACACAGTGGCATCTGAATGTCCTTCTC TGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAACTTCAAGAAACTACTAAATGAGGCATCCACCACTCATCACT GTGTGGAGACTGGAAGCCAGGAAGCATCTGCCATCTACTTCACTAGTGGGACCAGTGGTCTTCCCAAGATGGCAGAACATTCCTACTCGA GCCTGGGCCTCAAGGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCCTCTGATATAATGTGGACCATATCAGACACAGGTTGGATAC TGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACATTTGTTCATCTCTTGCCAAAGTTTGACCCACTGGTTATTC TAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATTGTTTACCGGATGTTGCTACAGCAGGATCTTTCCAGTTACA AGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCAGAAACTCTGGAGAACTGGAGGGCCCAGACAGGACTGGACA TCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCCAAGACAATGAAAATCAAACCAGGATACATGGGAACGGCTG CTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCCCCCGGCACAGAAGGAGACATTGGCATCAGGGTCAAACCCA TCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACAGCAGCCAACATTCGAGGAGACTTTTGGCTCCTTGGAGACC GGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAATGATATCATTAACTCCAGCGGGTACCGGATTGGACCCTCGG AGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTGATCAGCAGCCCAGACCCCGTCCGAGGAGAGGTGAAGGCCA CAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCAGCAAGTGGCCTCCTTCT GCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGCGGGATCTTCGGGC TCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAGGTTGCTCTTCCAGA GGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCTCCAAGGAGACAG ACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCCTGGAGGTCAGCCTGGTGGTGGCAGTGG CTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCTCATGCCAGCTGA GACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCGGGCATTCCGAACCC AGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGACAGGTGGCTTGCGG CCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGAGCAAAGCCCACCTCAGTGCTGGCCTCGTGG GCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACAGCATCGTGTCAG TGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCCCTGGCCTCAGGGCG GGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAGATCCACGCAGGAG AGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGCAGCTGAGGGTGGGA TCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACCCCATCCTGTTCC CTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGACGGTGCAGCTCAAAGCCT TGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAGCTCCTGTGTCTGG CACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCTGCAGATGCAGGCCA TGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGGTTCTGGTCATGG ACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTTACAGACTGGCCCAGGAGTCAGGCCTGG TCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCCTGCAGTGCTGGAGATGGAAGTGACCCGTGGTCATCGATAG CTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAATGGCAGAGAAAGTGGCCAATTATCACAGAGCATCAGAGCCG GAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCTGTCCACCCTGCAGCCAATGTCAACAGCGACTCTCAGCCCC GCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCGGCTAGACCCTTAAATCAGAATCTCTGAGGCTGGGAACTGC CATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCCCAGACTCACATGCAGTTAAAGAAACAATAATATAGAGAGA TTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACTCTAGGATAAAGCATCACAGCCAGGGTGTTGACATTGACAC AACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGTGTTTATTTTGTCCCATGCAGTTTTATCACACATGTAGGCT CATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCGACCACACCCATCACTCTCGCTCCTGCCCCCAGTGACCATG CTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCT CAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGTGCAGC TGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTATTAGATACGAGGTTTCAGCATATTGGCCAGGCTGGTCTTG AACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGGATAACAGGCGTGAGCTACCGCACCTGGCCGAGTTTGGTGT ATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGAACTACAGCCCTCGCATCTCCTGCTGCTCCTCCTCCCCCAC >1525_1525_2_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000396104_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=1079AA_BP=1 MNMHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSE NSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR IKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILN ILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIR ESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRG IKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCR GYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDT VDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQA PFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVE RMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIW IDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLAR -------------------------------------------------------------- >1525_1525_3_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000417235_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4372nt_BP=1442nt GCTTGAGTTACTGTGCTCTCTTCCAAGGCTGTAGGAGTTCTGGAGCTGCTGGCTGGAGAGGAGGGTGGACGAAGCTCTCTCTAGAAAGAC ATCCTGAGAGGACTTGGCAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAATGGGAAGGGGAAGGAATTAATGTGGAATT TCAGAGAACTGAGTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTGCAGCGTGGGGATCGTGTGGCAGTGGTGC TGCCCCGAGTGCCTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTTATGCCTGGAACCATCCAGATGAAATCCA CTGACATACTGTATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTCATCCAAGAAGTGGACACAGTGGCATCTG AATGTCCTTCTCTGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAACTTCAAGAAACTACTAAATGAGGCATCCA CCACTCATCACTGTGTGGAGACTGGAAGCCAGGAAGCATCTGCCATCTACTTCACTAGTGGGACCAGTGGTCTTCCCAAGATGGCAGAAC ATTCCTACTCGAGCCTGGGCCTCAAGGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCCTCTGATATAATGTGGACCATATCAGACA CAGGTTGGATACTGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACATTTGTTCATCTCTTGCCAAAGTTTGACC CACTGGTTATTCTAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATTGTTTACCGGATGTTGCTACAGCAGGATC TTTCCAGTTACAAGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCAGAAACTCTGGAGAACTGGAGGGCCCAGA CAGGACTGGACATCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCCAAGACAATGAAAATCAAACCAGGATACA TGGGAACGGCTGCTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCCCCCGGCACAGAAGGAGACATTGGCATCA GGGTCAAACCCATCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACAGCAGCCAACATTCGAGGAGACTTTTGGC TCCTTGGAGACCGGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAATGATATCATTAACTCCAGCGGGTACCGGA TTGGACCCTCGGAGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTGATCAGCAGCCCAGACCCCGTCCGAGGAG AGGTGAAGGCCACAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCAGCAAG TGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGCG GGATCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAGGT TGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCT CCAAGGAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCCTGGAGGTCAGCCTGG TGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCT CATGCCAGCTGAGACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCGGG CATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGACA GGTGGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGAGCAAAGCCCACCTCAGTG CTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACA GCATCGTGTCAGTGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCCCT GGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAGA TCCACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGCAG CTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACC CCATCCTGTTCCCTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGACGGTGC AGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAGC TCCTGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCTGC AGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGG TTCTGGTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTTACAGACTGGCCCAGG AGTCAGGCCTGGTCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCCTGCAGTGCTGGAGATGGAAGTGACCCGT GGTCATCGATAGCTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAATGGCAGAGAAAGTGGCCAATTATCACAGA GCATCAGAGCCGGAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCTGTCCACCCTGCAGCCAATGTCAACAGCG ACTCTCAGCCCCGCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCGGCTAGACCCTTAAATCAGAATCTCTGAG GCTGGGAACTGCCATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCCCAGACTCACATGCAGTTAAAGAAACAAT AATATAGAGAGATTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACTCTAGGATAAAGCATCACAGCCAGGGTGT TGACATTGACACAACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGTGTTTATTTTGTCCCATGCAGTTTTATCA CACATGTAGGCTCATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCGACCACACCCATCACTCTCGCTCCTGCCC CCAGTGACCATGCTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTTTTTTTTTGAGACAGAGTCT CACTCTGTTGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCCTGGGTTCAAGCAATTCTCCTGCCTCAGC CTCCCGTGCAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTATTAGATACGAGGTTTCAGCATATTGGCC AGGCTGGTCTTGAACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGGATAACAGGCGTGAGCTACCGCACCTGGC CGAGTTTGGTGTATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGAACTACAGCCCTCGCATCTCCTGCTGCTC >1525_1525_3_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000417235_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=1054AA_BP=0 LSYCALFQGCRSSGAAGWRGGWTKLSLERHPERTWQAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVL PRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEAST THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDP LVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYM GTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRANDIINSSGYRI GPSEVENALMEHPAVVETAVISSPDPVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADDPAVGGQQTQAALRGG IFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDTVDVDIPDKLRSLLMYAFGLLEVSLV VAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADR WLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPW PQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDP ILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQ -------------------------------------------------------------- >1525_1525_4_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000536134_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4464nt_BP=1534nt GAGTTACTGTGCTCTCTTCCAAGGCTGTAGGAGTTCTGGAGCTGCTGGCTGGAGAGGAGGGTGGACGAAGCTCTCTCTAGAAAGACATCC TGAGAGGACTTGGCAGGCCTGAATATGCATTGGCTGCGAAAAGTTCAGGGACTTTGCACCCTGTGGGGTACTCAGATGTCCAGCCGCACT CTCTACATTAATAGTAGGCAACTGGTGTCCCTGCAGTGGGGCCACCAGGAAGTGCCGGCCAAGTTTAACTTTGCTAGTGATGTGTTGGAT CACTGGGCTGACATGGAGAAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAATGGGAAGGGGAAGGAATTAATGTGGAAT TTCAGAGAACTGAGTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTGCAGCGTGGGGATCGTGTGGCAGTGGTG CTGCCCCGAGTGCCTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTTATGCCTGGAACCATCCAGATGAAATCC ACTGACATACTGTATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTCATCCAAGAAGTGGACACAGTGGCATCT GAATGTCCTTCTCTGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAACTTCAAGAAACTACTAAATGAGGCATCC ACCACTCATCACTGTGTGGAGACTGGAAGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCCTCTGATATAATGTGGACCATATCAGA CACAGGTTGGATACTGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACATTTGTTCATCTCTTGCCAAAGTTTGA CCCACTGGTTATTCTAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATTGTTTACCGGATGTTGCTACAGCAGGA TCTTTCCAGTTACAAGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCAGAAACTCTGGAGAACTGGAGGGCCCA GACAGGACTGGACATCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCCAAGACAATGAAAATCAAACCAGGATA CATGGGAACGGCTGCTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCCCCCGGCACAGAAGGAGACATTGGCAT CAGGGTCAAACCCATCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACAGCAGCCAACATTCGAGGAGACTTTTG GCTCCTTGGAGACCGGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAATGATATCATTAACTCCAGCGGGTACCG GATTGGACCCTCGGAGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTGATCAGCAGCCCAGACCCCGTCCGAGG AGAGGTGAAGGCCACAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCAGCA AGTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGG CGGGATCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAG GTTGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTT CTCCAAGGAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCCTGGAGGTCAGCCT GGTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAG CTCATGCCAGCTGAGACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCG GGCATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGA CAGGTGGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGAGCAAAGCCCACCTCAG TGCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAA CAGCATCGTGTCAGTGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCC CTGGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAA GATCCACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGC AGCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGA CCCCATCCTGTTCCCTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGACGGT GCAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACA GCTCCTGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCT GCAGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCG GGTTCTGGTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTTACAGACTGGCCCA GGAGTCAGGCCTGGTCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCCTGCAGTGCTGGAGATGGAAGTGACCC GTGGTCATCGATAGCTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAATGGCAGAGAAAGTGGCCAATTATCACA GAGCATCAGAGCCGGAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCTGTCCACCCTGCAGCCAATGTCAACAG CGACTCTCAGCCCCGCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCGGCTAGACCCTTAAATCAGAATCTCTG AGGCTGGGAACTGCCATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCCCAGACTCACATGCAGTTAAAGAAACA ATAATATAGAGAGATTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACTCTAGGATAAAGCATCACAGCCAGGGT GTTGACATTGACACAACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGTGTTTATTTTGTCCCATGCAGTTTTAT CACACATGTAGGCTCATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCGACCACACCCATCACTCTCGCTCCTGC CCCCAGTGACCATGCTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTTTTTTTTTGAGACAGAGT CTCACTCTGTTGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCCTGGGTTCAAGCAATTCTCCTGCCTCA GCCTCCCGTGCAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTATTAGATACGAGGTTTCAGCATATTGG CCAGGCTGGTCTTGAACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGGATAACAGGCGTGAGCTACCGCACCTG GCCGAGTTTGGTGTATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGAACTACAGCCCTCGCATCTCCTGCTGC >1525_1525_4_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000536134_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=849AA_BP=275 MRHPPLITVWRLEAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRML LQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEG DIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPD PVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGA RASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSL YVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSK AHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQG VSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAA LETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVM -------------------------------------------------------------- >1525_1525_5_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000573854_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4553nt_BP=1623nt GAGTTACTGTGCTCTCTTCCAAGGCTGTAGGAGTTCTGGAGCTGCTGGCTGGAGAGGAGGGTGGACGAAGCTCTCTCTAGAAAGACATCC TGAGAGGACTTGGCAGGCCTGAATATGCATTGGCTGCGAAAAGTTCAGGGACTTTGCACCCTGTGGGGTACTCAGATGTCCAGCCGCACT CTCTACATTAATAGTAGGCAACTGGTGTCCCTGCAGTGGGGCCACCAGGAAGTGCCGGCCAAGTTTAACTTTGCTAGTGATGTGTTGGAT CACTGGGCTGACATGGAGAAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAATGGGAAGGGGAAGGAATTAATGTGGAAT TTCAGAGAACTGAGTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTGCAGCGTGGGGATCGTGTGGCAGTGGTG CTGCCCCGAGTGCCTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTTATGCCTGGAACCATCCAGATGAAATCC ACTGACATACTGTATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTCATCCAAGAAGTGGACACAGTGGCATCT GAATGTCCTTCTCTGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAACTTCAAGAAACTACTAAATGAGGCATCC ACCACTCATCACTGTGTGGAGACTGGAAGCCAGGAAGCATCTGCCATCTACTTCACTAGTGGGACCAGTGGTCTTCCCAAGATGGCAGAA CATTCCTACTCGAGCCTGGGCCTCAAGGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCCTCTGATATAATGTGGACCATATCAGAC ACAGGTTGGATACTGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACATTTGTTCATCTCTTGCCAAAGTTTGAC CCACTGGTTATTCTAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATTGTTTACCGGATGTTGCTACAGCAGGAT CTTTCCAGTTACAAGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCAGAAACTCTGGAGAACTGGAGGGCCCAG ACAGGACTGGACATCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCCAAGACAATGAAAATCAAACCAGGATAC ATGGGAACGGCTGCTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCCCCCGGCACAGAAGGAGACATTGGCATC AGGGTCAAACCCATCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACAGCAGCCAACATTCGAGGAGACTTTTGG CTCCTTGGAGACCGGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAATGATATCATTAACTCCAGCGGGTACCGG ATTGGACCCTCGGAGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTGATCAGCAGCCCAGACCCCGTCCGAGGA GAGGTGAAGGCCACAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCAGCAA GTGGCCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGC GGGATCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAGG TTGCTCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTC TCCAAGGAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCCTGGAGGTCAGCCTG GTGGTGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGC TCATGCCAGCTGAGACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCGG GCATTCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGAC AGGTGGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGAGCAAAGCCCACCTCAGT GCTGGCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAAC AGCATCGTGTCAGTGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCCC TGGCCTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAG ATCCACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGCA GCTGAGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGAC CCCATCCTGTTCCCTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGACGGTG CAGCTCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAG CTCCTGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCTG CAGATGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGG GTTCTGGTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTTACAGACTGGCCCAG GAGTCAGGCCTGGTCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCCTGCAGTGCTGGAGATGGAAGTGACCCG TGGTCATCGATAGCTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAATGGCAGAGAAAGTGGCCAATTATCACAG AGCATCAGAGCCGGAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCTGTCCACCCTGCAGCCAATGTCAACAGC GACTCTCAGCCCCGCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCGGCTAGACCCTTAAATCAGAATCTCTGA GGCTGGGAACTGCCATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCCCAGACTCACATGCAGTTAAAGAAACAA TAATATAGAGAGATTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACTCTAGGATAAAGCATCACAGCCAGGGTG TTGACATTGACACAACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGTGTTTATTTTGTCCCATGCAGTTTTATC ACACATGTAGGCTCATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCGACCACACCCATCACTCTCGCTCCTGCC CCCAGTGACCATGCTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTTTTTTTTTGAGACAGAGTC TCACTCTGTTGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCCTGGGTTCAAGCAATTCTCCTGCCTCAG CCTCCCGTGCAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTATTAGATACGAGGTTTCAGCATATTGGC CAGGCTGGTCTTGAACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGGATAACAGGCGTGAGCTACCGCACCTGG CCGAGTTTGGTGTATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGAACTACAGCCCTCGCATCTCCTGCTGCT >1525_1525_5_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000573854_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=1082AA_BP=2 MAGLNMHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRE LSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECP SLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGW ILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGL DIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLG DRGIKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVAS FCRGYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKE TDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFR TQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIV SVERMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEG GIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLC LARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQKGLFYRLAQESG -------------------------------------------------------------- >1525_1525_6_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000575690_ABCC6_chr16_16263710_ENST00000205557_length(transcript)=4909nt_BP=1979nt GTAGGAGTTCTGGAGCTGCTGGCTGGAGAGGAGGGTGGACGAAGCTCTCTCTAGAAAGACATCCTGAGAGGACTTGGCAGAAAAAAAGGA GACAGAAATGTCAGACACTGTGATGGTTAATACTGAGTGTCAATTGATTGAATTGAAGGATACAAAGTGTTGATCCTGGATGTGTCTGTG AGGGTGTTGTCAAAAGAGATTAACATTTGAGTCGGTGGGCTGGGAGAGGCAGACCCACCCTTAATCTGGGTAGGAACCACCTAATCCAGC ATGACTAGAATATAAGCAGGCAGAAAAATATGAAAAGAGAGACTGGCCTAGCTTCCCAGCCTAGATCTTTCTTCCGTACTGGATGCTTCC TGCACTTGAACATCAGACTCCAGGTTCTTCAGTTTTGGAACTCAAACTGGCTCTCCTTGCACCTCAGCCTGCAGATGGCCTATTGTGGGA CCTTGTGATCATGCCTGAATATGCATTGGCTGCGAAAAGTTCAGGGACTTTGCACCCTGTGGGGTACTCAGATGTCCAGCCGCACTCTCT ACATTAATAGTAGGCAACTGGTGTCCCTGCAGTGGGGCCACCAGGAAGTGCCGGCCAAGTTTAACTTTGCTAGTGATGTGTTGGATCACT GGGCTGACATGGAGAAGGCTGGCAAGCGACTCCCAAGCCCAGCCCTGTGGTGGGTGAATGGGAAGGGGAAGGAATTAATGTGGAATTTCA GAGAACTGAGTGAAAACAGCCAGCAGGCAGCCAACGTCCTCTCGGGAGCCTGTGGCCTGCAGCGTGGGGATCGTGTGGCAGTGGTGCTGC CCCGAGTGCCTGAGTGGTGGCTGGTGATCCTGGGCTGCATTCGAGCAGGTCTCATCTTTATGCCTGGAACCATCCAGATGAAATCCACTG ACATACTGTATAGGTTGCAGATGTCTAAGGCCAAGGCTATTGTTGCTGGGGATGAAGTCATCCAAGAAGTGGACACAGTGGCATCTGAAT GTCCTTCTCTGAGAATTAAGCTACTGGTGTCTGAGAAAAGCTGTGATGGGTGGCTGAACTTCAAGAAACTACTAAATGAGGCATCCACCA CTCATCACTGTGTGGAGACTGGAAGCCAGGAAGCATCTGCCATCTACTTCACTAGTGGGACCAGTGGTCTTCCCAAGATGGCAGAACATT CCTACTCGAGCCTGGGCCTCAAGGCCAAGATGGATGCTGGTTGGACAGGCCTGCAAGCCTCTGATATAATGTGGACCATATCAGACACAG GTTGGATACTGAACATCTTGTGCTCACTTATGGAACCTTGGGCATTAGGAGCATGCACATTTGTTCATCTCTTGCCAAAGTTTGACCCAC TGGTTATTCTAAAGACACTCTCCAGTTATCCAATCAAGAGTATGATGGGTGCCCCCATTGTTTACCGGATGTTGCTACAGCAGGATCTTT CCAGTTACAAGTTCCCCCATCTACAGAACTGCGTCACTGTAGGGGAGTCCCTTCTTCCAGAAACTCTGGAGAACTGGAGGGCCCAGACAG GACTGGACATCCGAGAATCCTATGGCCAGACAGAAACGGGATTAACTTGCATGGTTTCCAAGACAATGAAAATCAAACCAGGATACATGG GAACGGCTGCTTCCTGTTATGATGTACAGATCATAGATGATAAGGGCAACGTCCTGCCCCCCGGCACAGAAGGAGACATTGGCATCAGGG TCAAACCCATCAGGCCTATAGGCATCTTCTCTGGCTATGTGGACAATCCCGACAAGACAGCAGCCAACATTCGAGGAGACTTTTGGCTCC TTGGAGACCGGGGAATCAAAGATGAAGATGGGTATTTCCAGTTTATGGGACGGGCAAATGATATCATTAACTCCAGCGGGTACCGGATTG GACCCTCGGAGGTAGAGAATGCACTGATGGAGCACCCTGCTGTGGTTGAGACGGCTGTGATCAGCAGCCCAGACCCCGTCCGAGGAGAGG TGAAGGCCACAGTGCACCTGGCCTACCTGCGTGCCGTGGGCACCCCCCTCTGCCTCTACGCACTCTTCCTCTTCCTCTGCCAGCAAGTGG CCTCCTTCTGCCGGGGCTACTGGCTGAGCCTGTGGGCGGACGACCCTGCAGTAGGTGGGCAGCAGACGCAGGCAGCCCTGCGTGGCGGGA TCTTCGGGCTCCTCGGCTGTCTCCAAGCCATTGGGCTGTTTGCCTCCATGGCTGCGGTGCTCCTAGGTGGGGCCCGGGCATCCAGGTTGC TCTTCCAGAGGCTCCTGTGGGATGTGGTGCGATCTCCCATCAGCTTCTTTGAGCGGACACCCATTGGTCACCTGCTAAACCGCTTCTCCA AGGAGACAGACACGGTTGACGTGGACATTCCAGACAAACTCCGGTCCCTGCTGATGTACGCCTTTGGACTCCTGGAGGTCAGCCTGGTGG TGGCAGTGGCTACCCCACTGGCCACTGTGGCCATCCTGCCACTGTTTCTCCTCTACGCTGGGTTTCAGAGCCTGTATGTGGTTAGCTCAT GCCAGCTGAGACGCTTGGAGTCAGCCAGCTACTCGTCTGTCTGCTCCCACATGGCTGAGACGTTCCAGGGCAGCACAGTGGTCCGGGCAT TCCGAACCCAGGCCCCCTTTGTGGCTCAGAACAATGCTCGCGTAGATGAAAGCCAGAGGATCAGTTTCCCGCGACTGGTGGCTGACAGGT GGCTTGCGGCCAATGTGGAGCTCCTGGGGAATGGCCTGGTGTTTGCAGCTGCCACGTGTGCTGTGCTGAGCAAAGCCCACCTCAGTGCTG GCCTCGTGGGCTTCTCTGTCTCTGCTGCCCTCCAGGTGACCCAGACACTGCAGTGGGTTGTTCGCAACTGGACAGACCTAGAGAACAGCA TCGTGTCAGTGGAGCGGATGCAGGACTATGCCTGGACGCCCAAGGAGGCTCCCTGGAGGCTGCCCACATGTGCAGCTCAGCCCCCCTGGC CTCAGGGCGGGCAGATCGAGTTCCGGGACTTTGGGCTAAGATACCGACCTGAGCTCCCGCTGGCTGTGCAGGGCGTGTCCTTCAAGATCC ACGCAGGAGAGAAGGTGGGCATCGTTGGCAGGACCGGGGCAGGGAAGTCCTCCCTGGCCAGTGGGCTGCTGCGGCTCCAGGAGGCAGCTG AGGGTGGGATCTGGATCGACGGGGTCCCCATTGCCCACGTGGGGCTGCACACACTGCGCTCCAGGATCAGCATCATCCCCCAGGACCCCA TCCTGTTCCCTGGCTCTCTGCGGATGAACCTCGACCTGCTGCAGGAGCACTCGGACGAGGCTATCTGGGCAGCCCTGGAGACGGTGCAGC TCAAAGCCTTGGTGGCCAGCCTGCCCGGCCAGCTGCAGTACAAGTGTGCTGACCGAGGCGAGGACCTGAGCGTGGGCCAGAAACAGCTCC TGTGTCTGGCACGTGCCCTTCTCCGGAAGACCCAGATCCTCATCCTGGACGAGGCTACTGCTGCCGTGGACCCTGGCACGGAGCTGCAGA TGCAGGCCATGCTCGGGAGCTGGTTTGCACAGTGCACTGTGCTGCTCATTGCCCACCGCCTGCGCTCCGTGATGGACTGTGCCCGGGTTC TGGTCATGGACAAGGGGCAGGTGGCAGAGAGCGGCAGCCCGGCCCAGCTGCTGGCCCAGAAGGGCCTGTTTTACAGACTGGCCCAGGAGT CAGGCCTGGTCTGAGCCAGGACCCTCAACCGTACCCCAGTTGGACCAGCCCGCACAGCCTGCAGTGCTGGAGATGGAAGTGACCCGTGGT CATCGATAGCTCCACACGATATTGAGTCTAGACCTGTGTTTGCTCTCTGGGAGGAAAATGGCAGAGAAAGTGGCCAATTATCACAGAGCA TCAGAGCCGGAAGGACCTAGCAATACACAGGTCTGCCCGGGCAGGGCCCATCTCGCCCTGTCCACCCTGCAGCCAATGTCAACAGCGACT CTCAGCCCCGCTGTACTCTGGACTCACCTGGGGGCCTCAAGCACATGCCCAGGCTCCCGGCTAGACCCTTAAATCAGAATCTCTGAGGCT GGGAACTGCCATGCTGTGTGTACTTTTTACAAATTAACACTTTTATTTTGGGATAATCCCAGACTCACATGCAGTTAAAGAAACAATAAT ATAGAGAGATTCGTGTACTTGGTACCCCATTTCACCCAATGGTAACATCTTGCAAAACTCTAGGATAAAGCATCACAGCCAGGGTGTTGA CATTGACACAACAATCTTGCTCGATTTCCCGTTTTACCTGTACTCCTGTGTGTGTGTGTGTTTATTTTGTCCCATGCAGTTTTATCACAC ATGTAGGCTCATGAATCCACACCAGGGTGAGGATACGGAATAGCCACCACCATTTTCCGACCACACCCATCACTCTCGCTCCTGCCCCCA GTGACCATGCTCTGTTCTCCAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCAC TCTGTTGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACTGCAACCTCCACATCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTC CCGTGCAGCTGAGATTACAGGCGTGCGCCACCATGCCTGGCTAACTTGTGTAATTTTTATTAGATACGAGGTTTCAGCATATTGGCCAGG CTGGTCTTGAACTCCTGGCCTCATGTGATCCACCCTCCTCGGCCTCCCAAAGTGTTGGGATAACAGGCGTGAGCTACCGCACCTGGCCGA GTTTGGTGTATAATTTTAAAGCTCCCCCATAGGATTCCAATGTGCGGCCAGGACTGAGAACTACAGCCCTCGCATCTCCTGCTGCTCCTC >1525_1525_6_ACSM2A-ABCC6_ACSM2A_chr16_20492243_ENST00000575690_ABCC6_chr16_16263710_ENST00000205557_length(amino acids)=1079AA_BP=1 MNMHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSE NSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR IKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILN ILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIR ESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRG IKDEDGYFQFMGRANDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCR GYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDT VDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQA PFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVE RMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIW IDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLAR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ACSM2A-ABCC6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ACSM2A-ABCC6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ACSM2A-ABCC6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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