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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACSS3-STAU2 (FusionGDB2 ID:1552)

Fusion Gene Summary for ACSS3-STAU2

check button Fusion gene summary
Fusion gene informationFusion gene name: ACSS3-STAU2
Fusion gene ID: 1552
HgeneTgene
Gene symbol

ACSS3

STAU2

Gene ID

79611

27067

Gene nameacyl-CoA synthetase short chain family member 3staufen double-stranded RNA binding protein 2
Synonyms-39K2|39K3
Cytomap

12q21.31

8q21.11

Type of geneprotein-codingprotein-coding
Descriptionacyl-CoA synthetase short-chain family member 3, mitochondrialAMP-binding enzyme, 33217acetate--CoA ligase 3propionate--CoA ligasedouble-stranded RNA-binding protein Staufen homolog 2staufen homolog 2staufen, RNA binding protein, homolog 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000261206, ENST00000548058, 
ENST00000548324, 		ENST00000355780, 
ENST00000517542, ENST00000519961, 
ENST00000521419, ENST00000521451, 
ENST00000521727, ENST00000522509, 
ENST00000522962, ENST00000524104, 
ENST00000521210, ENST00000522695, 
ENST00000523558, ENST00000524300, 
Fusion gene scores* DoF score9 X 7 X 2=12621 X 18 X 11=4158
# samples 829
** MAII scorelog2(8/126*10)=-0.655351828612554
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/4158*10)=-3.84176495284344
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACSS3 [Title/Abstract] AND STAU2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACSS3(81537026)-STAU2(74334937), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ACSS3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across STAU2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A7EI-01AACSS3chr12

81537026

-STAU2chr8

74334937

-
ChimerDB4SARCTCGA-DX-A7EIACSS3chr12

81537026

+STAU2chr8

74334937

-


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Fusion Gene ORF analysis for ACSS3-STAU2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261206ENST00000355780ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000517542ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000519961ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000521419ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000521451ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000521727ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000522509ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000522962ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000261206ENST00000524104ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000355780ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000517542ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000519961ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000521419ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000521451ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000521727ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000522509ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000522962ACSS3chr12

81537026

+STAU2chr8

74334937

-
5CDS-intronENST00000548058ENST00000524104ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000261206ENST00000521210ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000261206ENST00000522695ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000261206ENST00000523558ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000261206ENST00000524300ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000548058ENST00000521210ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000548058ENST00000522695ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000548058ENST00000523558ACSS3chr12

81537026

+STAU2chr8

74334937

-
In-frameENST00000548058ENST00000524300ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-3CDSENST00000548324ENST00000521210ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-3CDSENST00000548324ENST00000522695ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-3CDSENST00000548324ENST00000523558ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-3CDSENST00000548324ENST00000524300ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000355780ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000517542ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000519961ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000521419ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000521451ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000521727ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000522509ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000522962ACSS3chr12

81537026

+STAU2chr8

74334937

-
intron-intronENST00000548324ENST00000524104ACSS3chr12

81537026

+STAU2chr8

74334937

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000548058ACSS3chr1281537026+ENST00000522695STAU2chr874334937-301718317392013424
ENST00000548058ACSS3chr1281537026+ENST00000524300STAU2chr874334937-301518317392013424
ENST00000548058ACSS3chr1281537026+ENST00000523558STAU2chr874334937-225618317392013424
ENST00000548058ACSS3chr1281537026+ENST00000521210STAU2chr874334937-217418317392013424
ENST00000261206ACSS3chr1281537026+ENST00000522695STAU2chr874334937-2168982641164366
ENST00000261206ACSS3chr1281537026+ENST00000524300STAU2chr874334937-2166982641164366
ENST00000261206ACSS3chr1281537026+ENST00000523558STAU2chr874334937-1407982641164366
ENST00000261206ACSS3chr1281537026+ENST00000521210STAU2chr874334937-1325982641164366

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000548058ENST00000522695ACSS3chr1281537026+STAU2chr874334937-0.0005596820.99944025
ENST00000548058ENST00000524300ACSS3chr1281537026+STAU2chr874334937-0.0005498240.99945015
ENST00000548058ENST00000523558ACSS3chr1281537026+STAU2chr874334937-0.0016368590.9983632
ENST00000548058ENST00000521210ACSS3chr1281537026+STAU2chr874334937-0.0013486630.9986513
ENST00000261206ENST00000522695ACSS3chr1281537026+STAU2chr874334937-0.0004423290.9995577
ENST00000261206ENST00000524300ACSS3chr1281537026+STAU2chr874334937-0.0004382390.9995617
ENST00000261206ENST00000523558ACSS3chr1281537026+STAU2chr874334937-0.0012620730.998738
ENST00000261206ENST00000521210ACSS3chr1281537026+STAU2chr874334937-0.0008883350.9991116

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Fusion Genomic Features for ACSS3-STAU2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ACSS3-STAU2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:81537026/chr8:74334937)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSS3chr12:81537026chr8:74334937ENST00000548058+516227_230307687.0RegionCoenzyme A binding
TgeneSTAU2chr12:81537026chr8:74334937ENST0000052410406207_2740106.0DomainDRBM 3
TgeneSTAU2chr12:81537026chr8:74334937ENST0000052410406307_3750106.0DomainDRBM 4
TgeneSTAU2chr12:81537026chr8:74334937ENST00000524104068_750106.0DomainDRBM 1
TgeneSTAU2chr12:81537026chr8:74334937ENST000005241040695_1810106.0DomainDRBM 2
TgeneSTAU2chr12:81537026chr8:74334937ENST0000052410406273_2910106.0MotifNuclear localization signal 1
TgeneSTAU2chr12:81537026chr8:74334937ENST0000052410406373_4120106.0MotifNuclear localization signal 2
TgeneSTAU2chr12:81537026chr8:74334937ENST0000052410406381_5700106.0RegionRequired for dendritic transport

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSS3chr12:81537026chr8:74334937ENST00000548058+516425_427307687.0Nucleotide bindingATP
HgeneACSS3chr12:81537026chr8:74334937ENST00000548058+516446_451307687.0Nucleotide bindingATP
HgeneACSS3chr12:81537026chr8:74334937ENST00000548324+111425_4270369.0Nucleotide bindingATP
HgeneACSS3chr12:81537026chr8:74334937ENST00000548324+111446_4510369.0Nucleotide bindingATP
HgeneACSS3chr12:81537026chr8:74334937ENST00000548324+111227_2300369.0RegionCoenzyme A binding


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Fusion Gene Sequence for ACSS3-STAU2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1552_1552_1_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000521210_length(transcript)=1325nt_BP=982nt
GGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTGGCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCG
TAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGCCCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGT
CCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGGCAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTC
GGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTACAAGCCCTGGACCAAAACGCTGGAGAACAAACACTC
GCCCTCTACCAGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGC
TATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTT
GGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAG
GATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGT
TACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGA
CAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGC
CCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTT
AAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGCAATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAA
GCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGCTCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCT
CCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATGAGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCAT

>1552_1552_1_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000521210_length(amino acids)=366AA_BP=306
MKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAALRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPW
TKTLENKHSPSTRFVEGMLNICYNAVDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQA
MYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDL
DWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCK

--------------------------------------------------------------
>1552_1552_2_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000522695_length(transcript)=2168nt_BP=982nt
GGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTGGCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCG
TAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGCCCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGT
CCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGGCAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTC
GGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTACAAGCCCTGGACCAAAACGCTGGAGAACAAACACTC
GCCCTCTACCAGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGC
TATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTT
GGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAG
GATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGT
TACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGA
CAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGC
CCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTT
AAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGCAATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAA
GCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGCTCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCT
CCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATGAGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCAT
TATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATACATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTT
GAGCATTTCCCTTGGAACTCGAGATCAGATCATAACTCATTTGCCTAGAGGCAGCAGAAATCTGATCCTGCTACTGGAGCTTAAAATAAC
AAGTAAAGAAAAGTGTTAGAAACAAAGCTAAAATTTTAACATGATTAATAATAGAGAAGTTGGGTTTGGTTCTGTTGTTATGATTGTTTT
GTCGTGGTGCTTGTGTTCAGTTATATTCTCTCTCTCTCTCATTTCAAATACTGCTTGACAATTCGAAAATGAACCAATGATGTGCTGTGG
AATGTGATGGTTGTCTTCATATAGAGTCACATGGTTTCTCTTTTTATGCAGATATTTATAATCTTCATCCTATATCAGTAGGAATAACTA
TAAGGTGCACTACAAAAAGATGTATGCAAACAAACATGTTTTAAATCAGGTCAGATATCTGATGAAAAATACGAACTAATGTTAAGAGCA
AGTAGTTTCAACATACTCCAGGAACTGAGAAACAAAACAAAGCAATTGTGGGTTTTGAGCTCCATATACTCTTAGCAAGTAAGGGGGCGT
CTTGCCCCTATATATCATCTTCCCGGATTCCACTCCCTGTTGTGGGAATCGCGCCCACCCCCATCCGTGTGTTGTAGCCACTCACGGTTT
GCATCAAGAGTGTTTTTTGTAACTGCCTCTGGACTTGGGACAGTGAGTAGGATCAAAAATAAATAATGTACATGACGGGGAAGGGAAAAA
CCTGTTGGAGTTGCTTCCAGCCAGCCACGCTCCGGGCCAGCATGTTGGAATCCAGCGTGGAGCAGATGCAGTAAAAATGTGGTTGGTTTC

>1552_1552_2_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000522695_length(amino acids)=366AA_BP=306
MKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAALRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPW
TKTLENKHSPSTRFVEGMLNICYNAVDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQA
MYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDL
DWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCK

--------------------------------------------------------------
>1552_1552_3_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000523558_length(transcript)=1407nt_BP=982nt
GGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTGGCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCG
TAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGCCCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGT
CCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGGCAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTC
GGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTACAAGCCCTGGACCAAAACGCTGGAGAACAAACACTC
GCCCTCTACCAGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGC
TATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTT
GGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAG
GATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGT
TACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGA
CAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGC
CCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTT
AAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGCAATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAA
GCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGCTCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCT
CCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATGAGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCAT
TATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATACATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTT

>1552_1552_3_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000523558_length(amino acids)=366AA_BP=306
MKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAALRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPW
TKTLENKHSPSTRFVEGMLNICYNAVDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQA
MYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDL
DWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCK

--------------------------------------------------------------
>1552_1552_4_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000524300_length(transcript)=2166nt_BP=982nt
GGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTGGCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCG
TAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGCCCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGT
CCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGGCAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTC
GGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTACAAGCCCTGGACCAAAACGCTGGAGAACAAACACTC
GCCCTCTACCAGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGTTGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGC
TATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAAAGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTT
GGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTATGATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAG
GATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACTAAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGT
TACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACTTGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGA
CAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCCCGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGC
CCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCTTTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTT
AAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGCAATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAA
GCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGCTCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCT
CCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATGAGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCAT
TATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATACATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTT
GAGCATTTCCCTTGGAACTCGAGATCAGATCATAACTCATTTGCCTAGAGGCAGCAGAAATCTGATCCTGCTACTGGAGCTTAAAATAAC
AAGTAAAGAAAAGTGTTAGAAACAAAGCTAAAATTTTAACATGATTAATAATAGAGAAGTTGGGTTTGGTTCTGTTGTTATGATTGTTTT
GTCGTGGTGCTTGTGTTCAGTTATATTCTCTCTCTCTCTCATTTCAAATACTGCTTGACAATTCGAAAATGAACCAATGATGTGCTGTGG
AATGTGATGGTTGTCTTCATATAGAGTCACATGGTTTCTCTTTTTATGCAGATATTTATAATCTTCATCCTATATCAGTAGGAATAACTA
TAAGGTGCACTACAAAAAGATGTATGCAAACAAACATGTTTTAAATCAGGTCAGATATCTGATGAAAAATACGAACTAATGTTAAGAGCA
AGTAGTTTCAACATACTCCAGGAACTGAGAAACAAAACAAAGCAATTGTGGGTTTTGAGCTCCATATACTCTTAGCAAGTAAGGGGGCGT
CTTGCCCCTATATATCATCTTCCCGGATTCCACTCCCTGTTGTGGGAATCGCGCCCACCCCCATCCGTGTGTTGTAGCCACTCACGGTTT
GCATCAAGAGTGTTTTTTGTAACTGCCTCTGGACTTGGGACAGTGAGTAGGATCAAAAATAAATAATGTACATGACGGGGAAGGGAAAAA
CCTGTTGGAGTTGCTTCCAGCCAGCCACGCTCCGGGCCAGCATGTTGGAATCCAGCGTGGAGCAGATGCAGTAAAAATGTGGTTGGTTTC

>1552_1552_4_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000261206_STAU2_chr8_74334937_ENST00000524300_length(amino acids)=366AA_BP=306
MKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAALRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPW
TKTLENKHSPSTRFVEGMLNICYNAVDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQA
MYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDL
DWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKAALSALKQFSEQGLDPIDGAMNIEKGSLEKQAKHLREKADNNQAPPGSIAQDCK

--------------------------------------------------------------
>1552_1552_5_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000521210_length(transcript)=2174nt_BP=1831nt
CTTTCTTTTTACATTTTCCCAGTTTCCTCTTTTGATTCATCTTTACTTACTTCCTATTTTTGTTTTTTGTTTATTTGTTTGTTTTGTTTT
CTCATTAGAAAAGCCACAGAAACTCCAAGCAGGCAAATTAGAAGGGAGGCAATGCAACAAGTCCTATCTGTTCTCTGTCTAGATCACATG
CGGAGTCTGGTCAGCAGGTGAATCCGCATCCCAGTGGGGTCACCTTCCCTGTGACCTGTCAATCACCCCAAGAAGCACTTCCCAATTTGT
CTGGCACAACCTCCTTCCACTCCTCCTACCCTCTCAGTGGTCAGGAAATCCCGGAGCAGTCCTTGCCCTGGAGCTGCTTGTGTTTTTAGT
AACCAGGGACTGAGCTGATTTTGAAAAATCAATCAATCAATAAATAACAATCAAAGAGCCTTGCCTCAACGCACCGAGTTGCTGGTTTCC
TGCAGGTCAGAGGCGATGCCACCTCCACCAACGACCTTCCAAAGATTAAACCAGCCGTGTACAAACTGCTGGATTGAAAATTGAGAGATG
GGCCGTTGGCCTCCTCCTAGGAGTACTTGTGTGTTGAAATCGGAAGGACGTTCTGGAGTTTGAGCGCGATTTTTCCCGGAAGGCTGCGGG
GTTGGAAGTGCATGTTGGGGTTTGGATCTCGTGCAGCAGCGCAACTAACCTGCTGCAACGGCGCTGTGACACCCCTGTCCCGGGGCCCCC
ACTTTAGCCTGTTGCTTCTCTGGTCGCTCCAGGTCGGTTTTTCCCGGCGACTCTAGTGTGGCTTCCAAACTTCTGGGCTCTGGGCTCACT
TCGGAATTTGCCCCCGCCCCCTACTCCCTTCCCTCAGGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTG
GCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCGTAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGC
CCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGTCCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGG
CAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTCGGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTA
CAAGCCCTGGACCAAAACGCTGGAGAACAAACACTCGCCCTCTACCAGGTGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGT
TGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAA
AGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTAT
GATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACT
AAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACT
TGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCC
CGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCT
TTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTTAAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGC
AATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAAGCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGC
TCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCTCCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATG
AGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCATTATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATA

>1552_1552_5_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000521210_length(amino acids)=424AA_BP=364
MVAPGRFFPATLVWLPNFWALGSLRNLPPPPTPFPQAPGSCKSTICRTLGDRGWPEEMKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAA
LRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNAVDRHIEN
GKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDH
VKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTT

--------------------------------------------------------------
>1552_1552_6_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000522695_length(transcript)=3017nt_BP=1831nt
CTTTCTTTTTACATTTTCCCAGTTTCCTCTTTTGATTCATCTTTACTTACTTCCTATTTTTGTTTTTTGTTTATTTGTTTGTTTTGTTTT
CTCATTAGAAAAGCCACAGAAACTCCAAGCAGGCAAATTAGAAGGGAGGCAATGCAACAAGTCCTATCTGTTCTCTGTCTAGATCACATG
CGGAGTCTGGTCAGCAGGTGAATCCGCATCCCAGTGGGGTCACCTTCCCTGTGACCTGTCAATCACCCCAAGAAGCACTTCCCAATTTGT
CTGGCACAACCTCCTTCCACTCCTCCTACCCTCTCAGTGGTCAGGAAATCCCGGAGCAGTCCTTGCCCTGGAGCTGCTTGTGTTTTTAGT
AACCAGGGACTGAGCTGATTTTGAAAAATCAATCAATCAATAAATAACAATCAAAGAGCCTTGCCTCAACGCACCGAGTTGCTGGTTTCC
TGCAGGTCAGAGGCGATGCCACCTCCACCAACGACCTTCCAAAGATTAAACCAGCCGTGTACAAACTGCTGGATTGAAAATTGAGAGATG
GGCCGTTGGCCTCCTCCTAGGAGTACTTGTGTGTTGAAATCGGAAGGACGTTCTGGAGTTTGAGCGCGATTTTTCCCGGAAGGCTGCGGG
GTTGGAAGTGCATGTTGGGGTTTGGATCTCGTGCAGCAGCGCAACTAACCTGCTGCAACGGCGCTGTGACACCCCTGTCCCGGGGCCCCC
ACTTTAGCCTGTTGCTTCTCTGGTCGCTCCAGGTCGGTTTTTCCCGGCGACTCTAGTGTGGCTTCCAAACTTCTGGGCTCTGGGCTCACT
TCGGAATTTGCCCCCGCCCCCTACTCCCTTCCCTCAGGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTG
GCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCGTAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGC
CCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGTCCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGG
CAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTCGGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTA
CAAGCCCTGGACCAAAACGCTGGAGAACAAACACTCGCCCTCTACCAGGTGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGT
TGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAA
AGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTAT
GATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACT
AAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACT
TGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCC
CGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCT
TTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTTAAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGC
AATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAAGCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGC
TCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCTCCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATG
AGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCATTATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATA
CATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTTGAGCATTTCCCTTGGAACTCGAGATCAGATCATAACTCATTTGCCTAGAGG
CAGCAGAAATCTGATCCTGCTACTGGAGCTTAAAATAACAAGTAAAGAAAAGTGTTAGAAACAAAGCTAAAATTTTAACATGATTAATAA
TAGAGAAGTTGGGTTTGGTTCTGTTGTTATGATTGTTTTGTCGTGGTGCTTGTGTTCAGTTATATTCTCTCTCTCTCTCATTTCAAATAC
TGCTTGACAATTCGAAAATGAACCAATGATGTGCTGTGGAATGTGATGGTTGTCTTCATATAGAGTCACATGGTTTCTCTTTTTATGCAG
ATATTTATAATCTTCATCCTATATCAGTAGGAATAACTATAAGGTGCACTACAAAAAGATGTATGCAAACAAACATGTTTTAAATCAGGT
CAGATATCTGATGAAAAATACGAACTAATGTTAAGAGCAAGTAGTTTCAACATACTCCAGGAACTGAGAAACAAAACAAAGCAATTGTGG
GTTTTGAGCTCCATATACTCTTAGCAAGTAAGGGGGCGTCTTGCCCCTATATATCATCTTCCCGGATTCCACTCCCTGTTGTGGGAATCG
CGCCCACCCCCATCCGTGTGTTGTAGCCACTCACGGTTTGCATCAAGAGTGTTTTTTGTAACTGCCTCTGGACTTGGGACAGTGAGTAGG
ATCAAAAATAAATAATGTACATGACGGGGAAGGGAAAAACCTGTTGGAGTTGCTTCCAGCCAGCCACGCTCCGGGCCAGCATGTTGGAAT

>1552_1552_6_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000522695_length(amino acids)=424AA_BP=364
MVAPGRFFPATLVWLPNFWALGSLRNLPPPPTPFPQAPGSCKSTICRTLGDRGWPEEMKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAA
LRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNAVDRHIEN
GKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDH
VKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTT

--------------------------------------------------------------
>1552_1552_7_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000523558_length(transcript)=2256nt_BP=1831nt
CTTTCTTTTTACATTTTCCCAGTTTCCTCTTTTGATTCATCTTTACTTACTTCCTATTTTTGTTTTTTGTTTATTTGTTTGTTTTGTTTT
CTCATTAGAAAAGCCACAGAAACTCCAAGCAGGCAAATTAGAAGGGAGGCAATGCAACAAGTCCTATCTGTTCTCTGTCTAGATCACATG
CGGAGTCTGGTCAGCAGGTGAATCCGCATCCCAGTGGGGTCACCTTCCCTGTGACCTGTCAATCACCCCAAGAAGCACTTCCCAATTTGT
CTGGCACAACCTCCTTCCACTCCTCCTACCCTCTCAGTGGTCAGGAAATCCCGGAGCAGTCCTTGCCCTGGAGCTGCTTGTGTTTTTAGT
AACCAGGGACTGAGCTGATTTTGAAAAATCAATCAATCAATAAATAACAATCAAAGAGCCTTGCCTCAACGCACCGAGTTGCTGGTTTCC
TGCAGGTCAGAGGCGATGCCACCTCCACCAACGACCTTCCAAAGATTAAACCAGCCGTGTACAAACTGCTGGATTGAAAATTGAGAGATG
GGCCGTTGGCCTCCTCCTAGGAGTACTTGTGTGTTGAAATCGGAAGGACGTTCTGGAGTTTGAGCGCGATTTTTCCCGGAAGGCTGCGGG
GTTGGAAGTGCATGTTGGGGTTTGGATCTCGTGCAGCAGCGCAACTAACCTGCTGCAACGGCGCTGTGACACCCCTGTCCCGGGGCCCCC
ACTTTAGCCTGTTGCTTCTCTGGTCGCTCCAGGTCGGTTTTTCCCGGCGACTCTAGTGTGGCTTCCAAACTTCTGGGCTCTGGGCTCACT
TCGGAATTTGCCCCCGCCCCCTACTCCCTTCCCTCAGGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTG
GCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCGTAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGC
CCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGTCCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGG
CAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTCGGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTA
CAAGCCCTGGACCAAAACGCTGGAGAACAAACACTCGCCCTCTACCAGGTGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGT
TGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAA
AGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTAT
GATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACT
AAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACT
TGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCC
CGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCT
TTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTTAAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGC
AATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAAGCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGC
TCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCTCCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATG
AGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCATTATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATA
CATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTTGAGCATTTCCCTTGGAACTCGAGATCAGATCATAACTCATTTGCCTAGAGG

>1552_1552_7_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000523558_length(amino acids)=424AA_BP=364
MVAPGRFFPATLVWLPNFWALGSLRNLPPPPTPFPQAPGSCKSTICRTLGDRGWPEEMKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAA
LRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNAVDRHIEN
GKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDH
VKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTT

--------------------------------------------------------------
>1552_1552_8_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000524300_length(transcript)=3015nt_BP=1831nt
CTTTCTTTTTACATTTTCCCAGTTTCCTCTTTTGATTCATCTTTACTTACTTCCTATTTTTGTTTTTTGTTTATTTGTTTGTTTTGTTTT
CTCATTAGAAAAGCCACAGAAACTCCAAGCAGGCAAATTAGAAGGGAGGCAATGCAACAAGTCCTATCTGTTCTCTGTCTAGATCACATG
CGGAGTCTGGTCAGCAGGTGAATCCGCATCCCAGTGGGGTCACCTTCCCTGTGACCTGTCAATCACCCCAAGAAGCACTTCCCAATTTGT
CTGGCACAACCTCCTTCCACTCCTCCTACCCTCTCAGTGGTCAGGAAATCCCGGAGCAGTCCTTGCCCTGGAGCTGCTTGTGTTTTTAGT
AACCAGGGACTGAGCTGATTTTGAAAAATCAATCAATCAATAAATAACAATCAAAGAGCCTTGCCTCAACGCACCGAGTTGCTGGTTTCC
TGCAGGTCAGAGGCGATGCCACCTCCACCAACGACCTTCCAAAGATTAAACCAGCCGTGTACAAACTGCTGGATTGAAAATTGAGAGATG
GGCCGTTGGCCTCCTCCTAGGAGTACTTGTGTGTTGAAATCGGAAGGACGTTCTGGAGTTTGAGCGCGATTTTTCCCGGAAGGCTGCGGG
GTTGGAAGTGCATGTTGGGGTTTGGATCTCGTGCAGCAGCGCAACTAACCTGCTGCAACGGCGCTGTGACACCCCTGTCCCGGGGCCCCC
ACTTTAGCCTGTTGCTTCTCTGGTCGCTCCAGGTCGGTTTTTCCCGGCGACTCTAGTGTGGCTTCCAAACTTCTGGGCTCTGGGCTCACT
TCGGAATTTGCCCCCGCCCCCTACTCCCTTCCCTCAGGCCCCAGGAAGTTGCAAGAGTACCATTTGTCGCACACTCGGGGACCGCGGGTG
GCCGGAGGAGATGAAACCGTCTTGGCTGCAGTGTCGTAAAGTCACCAGCGCCGGGGGGCTCGGAGGGCCCTTGCCTGGGTCCTCTCCGGC
CCGGGGAGCCGGTGCGGCCCTCAGGGCTTTAGTGGTCCCGGGCCCGCGGGGCGGTCTCGGGGGCCGGGGATGCAGGGCACTGTCCTCCGG
CAGTGGCAGCGAGTACAAGACCCACTTCGCAGCCTCGGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCTGCCGAGCAGATCAGCTGGTA
CAAGCCCTGGACCAAAACGCTGGAGAACAAACACTCGCCCTCTACCAGGTGGTTTGTGGAAGGAATGCTTAACATTTGTTACAATGCCGT
TGATCGTCATATTGAAAATGGTAAAGGGGATAAGATTGCTATCATCTATGACAGTCCTGTTACAAACACTAAAGCAACCTTTACCTATAA
AGAAGTTCTGGAGCAGGTCTCCAAGCTGGCTGGTGTCTTGGTCAAGCATGGCATCAAGAAAGGTGACACTGTGGTTATCTACATGCCTAT
GATCCCACAGGCGATGTATACCATGTTGGCATGTGCAAGGATAGGTGCCATCCACAGTCTCATATTTGGAGGATTTGCTTCCAAAGAACT
AAGTAGTCGCATTGATCATGTAAAGCCCAAGGTGGTTGTTACAGCATCATTTGGCATTGAACCTGGAAGGAGGGTAGAGTACGTACCACT
TGTAGAAGAAGCGCTAAAAATAGGACAACACAAACCAGACAAAATTCTCATTTATAATCGTCCAAATATGGAGGCGGTTCCTTTGGCTCC
CGGTCGTGACCTTGATTGGGATGAAGAGATGGCAAAAGCCCAGTCACATGACTGTGTTCCTGTTCTTTCAGAACACCCACTGTATATTCT
TTACACATCTGGCACAACGGGGTTACCTAAGGCAGCCTTAAGTGCCTTGAAACAATTTTCTGAACAAGGACTGGATCCAATCGATGGAGC
AATGAATATCGAAAAAGGTTCTCTTGAAAAACAAGCCAAGCATCTGAGAGAGAAAGCGGACAATAACCAGGCACCCCCGGGCTCCATCGC
TCAGGACTGCAAGAAATCAAACTCGGCCGTCTAGCAGCTCCCAGAACCCGCGGCTGCCACCGCATCCTTATAAACCTGTCAGCACGCATG
AGGGTGTCTGTGTTCAGGGAAATGAATGACTAATACCATTATTTGAGTCTTATGTGAAGACAACACTATTCTAACACGAGAGATAATATA
CATGGTACTGTTTATTCAACTGGGGAAAAATAAAACTTTGAGCATTTCCCTTGGAACTCGAGATCAGATCATAACTCATTTGCCTAGAGG
CAGCAGAAATCTGATCCTGCTACTGGAGCTTAAAATAACAAGTAAAGAAAAGTGTTAGAAACAAAGCTAAAATTTTAACATGATTAATAA
TAGAGAAGTTGGGTTTGGTTCTGTTGTTATGATTGTTTTGTCGTGGTGCTTGTGTTCAGTTATATTCTCTCTCTCTCTCATTTCAAATAC
TGCTTGACAATTCGAAAATGAACCAATGATGTGCTGTGGAATGTGATGGTTGTCTTCATATAGAGTCACATGGTTTCTCTTTTTATGCAG
ATATTTATAATCTTCATCCTATATCAGTAGGAATAACTATAAGGTGCACTACAAAAAGATGTATGCAAACAAACATGTTTTAAATCAGGT
CAGATATCTGATGAAAAATACGAACTAATGTTAAGAGCAAGTAGTTTCAACATACTCCAGGAACTGAGAAACAAAACAAAGCAATTGTGG
GTTTTGAGCTCCATATACTCTTAGCAAGTAAGGGGGCGTCTTGCCCCTATATATCATCTTCCCGGATTCCACTCCCTGTTGTGGGAATCG
CGCCCACCCCCATCCGTGTGTTGTAGCCACTCACGGTTTGCATCAAGAGTGTTTTTTGTAACTGCCTCTGGACTTGGGACAGTGAGTAGG
ATCAAAAATAAATAATGTACATGACGGGGAAGGGAAAAACCTGTTGGAGTTGCTTCCAGCCAGCCACGCTCCGGGCCAGCATGTTGGAAT

>1552_1552_8_ACSS3-STAU2_ACSS3_chr12_81537026_ENST00000548058_STAU2_chr8_74334937_ENST00000524300_length(amino acids)=424AA_BP=364
MVAPGRFFPATLVWLPNFWALGSLRNLPPPPTPFPQAPGSCKSTICRTLGDRGWPEEMKPSWLQCRKVTSAGGLGGPLPGSSPARGAGAA
LRALVVPGPRGGLGGRGCRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNAVDRHIEN
GKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDH
VKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTT

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Fusion Gene PPI Analysis for ACSS3-STAU2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACSS3-STAU2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACSS3-STAU2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource