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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CENPP-LMO7 (FusionGDB2 ID:15725)

Fusion Gene Summary for CENPP-LMO7

Fusion gene summary

Fusion gene information	Fusion gene name: CENPP-LMO7
	Fusion gene ID: 15725
		Hgene	Tgene
	Gene symbol	CENPP	LMO7
	Gene ID	401541	4008
	Gene name	centromere protein P	LIM domain 7
	Synonyms	CENP-P	FBX20\|FBXO20\|LMO7b\|LOMP
	Cytomap	9q22.31	13q22.2
	Type of gene	protein-coding	protein-coding
	Description	centromere protein P	LIM domain only protein 7F-box only protein 20F-box protein Fbx20LIM domain only 7 proteinLMO-7zinc-finger domain-containing protein
	Modification date	20200313	20200313
	UniProtAcc	.	Q8WWI1
	Ensembl transtripts involved in fusion gene	ENST00000375587, ENST00000375576, ENST00000375579,	ENST00000605961, ENST00000321797, ENST00000341547, ENST00000357063, ENST00000377534, ENST00000465261, ENST00000526202,
Fusion gene scores	* DoF score	7 X 8 X 5=280	7 X 8 X 4=224
	# samples	9	8
	** MAII score	log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CENPP [Title/Abstract] AND LMO7 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CENPP(95094633)-LMO7(76423214), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	LMO7	GO:0045944	positive regulation of transcription by RNA polymerase II	17067998

Fusion gene breakpoints across CENPP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across LMO7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-36-1577	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+

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Fusion Gene ORF analysis for CENPP-LMO7

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000375587	ENST00000605961	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000321797	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000341547	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000357063	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000377534	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000465261	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
In-frame	ENST00000375587	ENST00000526202	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000321797	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000341547	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000357063	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000377534	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000465261	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375576	ENST00000526202	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000321797	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000341547	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000357063	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000377534	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000465261	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-3CDS	ENST00000375579	ENST00000526202	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-intron	ENST00000375576	ENST00000605961	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+
intron-intron	ENST00000375579	ENST00000605961	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000375587	CENPP	chr9	95094633	+	ENST00000341547	LMO7	chr13	76423214	+	3473	804	479	1549	356
ENST00000375587	CENPP	chr9	95094633	+	ENST00000357063	LMO7	chr13	76423214	+	3366	804	479	1510	343
ENST00000375587	CENPP	chr9	95094633	+	ENST00000377534	LMO7	chr13	76423214	+	3263	804	479	1342	287
ENST00000375587	CENPP	chr9	95094633	+	ENST00000321797	LMO7	chr13	76423214	+	2279	804	479	1549	356
ENST00000375587	CENPP	chr9	95094633	+	ENST00000526202	LMO7	chr13	76423214	+	1763	804	479	1549	356
ENST00000375587	CENPP	chr9	95094633	+	ENST00000465261	LMO7	chr13	76423214	+	2173	804	479	1510	343

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000375587	ENST00000341547	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.000672132	0.9993279
ENST00000375587	ENST00000357063	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.000222226	0.99977773
ENST00000375587	ENST00000377534	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.001050024	0.99894994
ENST00000375587	ENST00000321797	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.004127166	0.9958728
ENST00000375587	ENST00000526202	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.015474805	0.98452526
ENST00000375587	ENST00000465261	CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.001382649	0.9986173

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Fusion Genomic Features for CENPP-LMO7

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.0741658	0.92583424
CENPP	chr9	95094633	+	LMO7	chr13	76423214	+	0.0741658	0.92583424

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CENPP-LMO7

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:95094633/chr13:76423214)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	LMO7 Q8WWI1
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CENPP

chr9:95094633

chr13:76423214

ENST00000375587

1_71

289.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

LMO7

chr9:95094633

chr13:76423214

ENST00000341547

1612_1678

1101

1350.0

Domain

LIM zinc-binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

LMO7

chr9:95094633

chr13:76423214

ENST00000341547

1042_1128

1101

1350.0

Domain

PDZ

Tgene

LMO7

chr9:95094633

chr13:76423214

ENST00000341547

64_181

1101

1350.0

Domain

Calponin-homology (CH)

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Fusion Gene Sequence for CENPP-LMO7

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>15725_15725_1_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000321797_length(transcript)=2279nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGGTCAGTCAGTGGGAAGCGCATATGCTCCTACTGCA
ATAACATTCTGGGCAAAGGAGCCGCCATGATCATCGAGTCCCTGGGTCTTTGTTATCATTTGCATTGTTTTAAGTGTGTTGCCTGTGAGT
GTGACCTCGGAGGCTCTTCCTCAGGAGCTGAAGTCAGGATCAGAAACCACCAACTGTACTGCAACGACTGCTATCTCAGATTCAAATCTG
GACGGCCAACCGCCATGTGATGTAAGCCTCCATACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAA
ATATGTGTTGTATGTCTTTTTTGCTTTTTTTTTAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTG
GTAGAACCAGTATTTTTGTTGTTTATTTATAAGGTAATTGTGTGTGGGGAAAAGTGCAGTATTTACCTGTTGAATTCAGCATCTTGAGAG
CACAAGGGAAAAAATAAGAACCTACGAATATTTTTGAGGCAGATAATGATCTAGTTTGACTTTCTAGTTAGTGGTGTTTTGAAGAGGGTA
TTTTATTGTTTTTTAAAAAAAGGTTCTTAAACATTATTTGAAATAGTTAATATAAATACATAATTGCATTTGCTCTGTTTATTGTAATGT
ATTCTAAATTAATGCAGAACCATATGGAAAATTTCATTAAAATCTATCCCCAAATGTGCTTTCTGTATCCTTCCTTCTACCTATTATTCT
GATTTTTAAAAATGCAGTTAATGTACCATTTATTTGCTTGATGAAGGGAGCTCTATTTTCTTTACCAGAAATGTTGCTAAGTAATTCCCA
ATAGAAAGCTGCTTATTTTCATTAATGAAAAATAACCATGGTTTGTATACTAGAAGTCTTCTTCAGAAACTGGTGAGCCTTTCTGTTCAA

>15725_15725_1_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000321797_length(amino acids)=356AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------
>15725_15725_2_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000341547_length(transcript)=3473nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGGTCAGTCAGTGGGAAGCGCATATGCTCCTACTGCA
ATAACATTCTGGGCAAAGGAGCCGCCATGATCATCGAGTCCCTGGGTCTTTGTTATCATTTGCATTGTTTTAAGTGTGTTGCCTGTGAGT
GTGACCTCGGAGGCTCTTCCTCAGGAGCTGAAGTCAGGATCAGAAACCACCAACTGTACTGCAACGACTGCTATCTCAGATTCAAATCTG
GACGGCCAACCGCCATGTGATGTAAGCCTCCATACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAA
ATATGTGTTGTATGTCTTTTTTGCTTTTTTTTTAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTG
GTAGAACCAGTATTTTTGTTGTTTATTTATAAGGTAATTGTGTGTGGGGAAAAGTGCAGTATTTACCTGTTGAATTCAGCATCTTGAGAG
CACAAGGGAAAAAATAAGAACCTACGAATATTTTTGAGGCAGATAATGATCTAGTTTGACTTTCTAGTTAGTGGTGTTTTGAAGAGGGTA
TTTTATTGTTTTTTAAAAAAAGGTTCTTAAACATTATTTGAAATAGTTAATATAAATACATAATTGCATTTGCTCTGTTTATTGTAATGT
ATTCTAAATTAATGCAGAACCATATGGAAAATTTCATTAAAATCTATCCCCAAATGTGCTTTCTGTATCCTTCCTTCTACCTATTATTCT
GATTTTTAAAAATGCAGTTAATGTACCATTTATTTGCTTGATGAAGGGAGCTCTATTTTCTTTACCAGAAATGTTGCTAAGTAATTCCCA
ATAGAAAGCTGCTTATTTTCATTAATGAAAAATAACCATGGTTTGTATACTAGAAGTCTTCTTCAGAAACTGGTGAGCCTTTCTGTTCAA
TTGCATTTGTAAATAAACTTGCTGATGCATTTAACGAGTGGGTCGTCTTTTTCTTAGGTGTATGTGTCTGACCTCAGGCCTTTTAGCCAT
ATTTCAGTATGTGGCCTTTTTTGATGTTATGTTTTATCCAGTAGCTTTACTAAGGTATAATTGATGTAATAAACTGCATATATTTAAAGT
GTATACTTTGACAAATTTTGACATGGTGTATACCTTCGAAACTATGCCACAGTCTGGATGTGTTTACTGAAACATTTTAATAAGGAAGTT
TATTTTTGATAAAGTTATGTTTTTGGATACAATATATTTGTATGGTGAGAGTGATGAATTGTTGGATCATTTGAATAAAATCTTTTACTA
ACCCCATGATAAAAGGAGAAGACAACAGTGAGCTTAGAATATCTATAAAGCAAAAAATGTAGTCTCTTGTTTAAAAAATCTGGAGCGGGA
ATGCAAGGATACAAAACTTTAGCATGCTTTGAGCAAAAATTTAAACTTACTGGAATCTTTTATAATAATGTAAGTGGAATGGAGGATTCT
AGGAACTGAGAACTGTATTGGAATAGGTTCAAAATATGTAAGAAATGCTAATGTGGGAGATAAAAATTTTATTTAGTACTTATTCTGATT
ATTATTAAAGTAATAATGTGTTCCTTGAGGATAACTTGTCAAATGCCCCAAAGCATAAAGAATATAATTCTGAATCCCAAATTCCAAAGA
CAAGAACTCTGTGTTTGAATTCATTCTGCATATAATTATTTATAAGTATAGATTGTGAATTTTTCCATGTTCTTAAAATTATTTTTATCT
TTTTTCATGGTTGCATAGTGCTCCATTGTTTGGCCTTGGTAATATTTAGTTGATAATTCCATTACTGTGTATTTTTCACTTGTTTCTAAG
ATCAAACATTTTAATATGTGCATGTTATATATAAATATGTAAATTCTGTGATACTCTATGATCATCTCTTTCTTTATATTATTTTCATAG
ACATGAAATAGTTGCTCAGAGATTATGCATTTTAAGACACTCATAGTATATATTGCCAAAGTGGTTTCCAGAAAGGCACTGCTGGCTTCG
ACTCCTATAAGCAGCACGTGGGCTTGTTCATCTCACTGCATGTTTATGAAGATACAGTTCTTTTGCCTTGTTCTCTGCCTGATGTGTATG

>15725_15725_2_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000341547_length(amino acids)=356AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------
>15725_15725_3_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000357063_length(transcript)=3366nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGTGTGTTGCCTGTGAGTGTGACCTCGGAGGCTCTTC
CTCAGGAGCTGAAGTCAGGATCAGAAACCACCAACTGTACTGCAACGACTGCTATCTCAGATTCAAATCTGGACGGCCAACCGCCATGTG
ATGTAAGCCTCCATACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAAATATGTGTTGTATGTCTTT
TTTGCTTTTTTTTTAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTGGTAGAACCAGTATTTTTGT
TGTTTATTTATAAGGTAATTGTGTGTGGGGAAAAGTGCAGTATTTACCTGTTGAATTCAGCATCTTGAGAGCACAAGGGAAAAAATAAGA
ACCTACGAATATTTTTGAGGCAGATAATGATCTAGTTTGACTTTCTAGTTAGTGGTGTTTTGAAGAGGGTATTTTATTGTTTTTTAAAAA
AAGGTTCTTAAACATTATTTGAAATAGTTAATATAAATACATAATTGCATTTGCTCTGTTTATTGTAATGTATTCTAAATTAATGCAGAA
CCATATGGAAAATTTCATTAAAATCTATCCCCAAATGTGCTTTCTGTATCCTTCCTTCTACCTATTATTCTGATTTTTAAAAATGCAGTT
AATGTACCATTTATTTGCTTGATGAAGGGAGCTCTATTTTCTTTACCAGAAATGTTGCTAAGTAATTCCCAATAGAAAGCTGCTTATTTT
CATTAATGAAAAATAACCATGGTTTGTATACTAGAAGTCTTCTTCAGAAACTGGTGAGCCTTTCTGTTCAATTGCATTTGTAAATAAACT
TGCTGATGCATTTAACGAGTGGGTCGTCTTTTTCTTAGGTGTATGTGTCTGACCTCAGGCCTTTTAGCCATATTTCAGTATGTGGCCTTT
TTTGATGTTATGTTTTATCCAGTAGCTTTACTAAGGTATAATTGATGTAATAAACTGCATATATTTAAAGTGTATACTTTGACAAATTTT
GACATGGTGTATACCTTCGAAACTATGCCACAGTCTGGATGTGTTTACTGAAACATTTTAATAAGGAAGTTTATTTTTGATAAAGTTATG
TTTTTGGATACAATATATTTGTATGGTGAGAGTGATGAATTGTTGGATCATTTGAATAAAATCTTTTACTAACCCCATGATAAAAGGAGA
AGACAACAGTGAGCTTAGAATATCTATAAAGCAAAAAATGTAGTCTCTTGTTTAAAAAATCTGGAGCGGGAATGCAAGGATACAAAACTT
TAGCATGCTTTGAGCAAAAATTTAAACTTACTGGAATCTTTTATAATAATGTAAGTGGAATGGAGGATTCTAGGAACTGAGAACTGTATT
GGAATAGGTTCAAAATATGTAAGAAATGCTAATGTGGGAGATAAAAATTTTATTTAGTACTTATTCTGATTATTATTAAAGTAATAATGT
GTTCCTTGAGGATAACTTGTCAAATGCCCCAAAGCATAAAGAATATAATTCTGAATCCCAAATTCCAAAGACAAGAACTCTGTGTTTGAA
TTCATTCTGCATATAATTATTTATAAGTATAGATTGTGAATTTTTCCATGTTCTTAAAATTATTTTTATCTTTTTTCATGGTTGCATAGT
GCTCCATTGTTTGGCCTTGGTAATATTTAGTTGATAATTCCATTACTGTGTATTTTTCACTTGTTTCTAAGATCAAACATTTTAATATGT
GCATGTTATATATAAATATGTAAATTCTGTGATACTCTATGATCATCTCTTTCTTTATATTATTTTCATAGACATGAAATAGTTGCTCAG
AGATTATGCATTTTAAGACACTCATAGTATATATTGCCAAAGTGGTTTCCAGAAAGGCACTGCTGGCTTCGACTCCTATAAGCAGCACGT
GGGCTTGTTCATCTCACTGCATGTTTATGAAGATACAGTTCTTTTGCCTTGTTCTCTGCCTGATGTGTATGCAGAGGCAGCCCTCAATAT

>15725_15725_3_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000357063_length(amino acids)=343AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------
>15725_15725_4_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000377534_length(transcript)=3263nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGCTGGACGGCCAACCGCCATGTGATGTAAGCCTCCA
TACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAAATATGTGTTGTATGTCTTTTTTGCTTTTTTTT
TAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTGGTAGAACCAGTATTTTTGTTGTTTATTTATAA
GGTAATTGTGTGTGGGGAAAAGTGCAGTATTTACCTGTTGAATTCAGCATCTTGAGAGCACAAGGGAAAAAATAAGAACCTACGAATATT
TTTGAGGCAGATAATGATCTAGTTTGACTTTCTAGTTAGTGGTGTTTTGAAGAGGGTATTTTATTGTTTTTTAAAAAAAGGTTCTTAAAC
ATTATTTGAAATAGTTAATATAAATACATAATTGCATTTGCTCTGTTTATTGTAATGTATTCTAAATTAATGCAGAACCATATGGAAAAT
TTCATTAAAATCTATCCCCAAATGTGCTTTCTGTATCCTTCCTTCTACCTATTATTCTGATTTTTAAAAATGCAGTTAATGTACCATTTA
TTTGCTTGATGAAGGGAGCTCTATTTTCTTTACCAGAAATGTTGCTAAGTAATTCCCAATAGAAAGCTGCTTATTTTCATTAATGAAAAA
TAACCATGGTTTGTATACTAGAAGTCTTCTTCAGAAACTGGTGAGCCTTTCTGTTCAATTGCATTTGTAAATAAACTTGCTGATGCATTT
AACGAGTGGGTCGTCTTTTTCTTAGGTGTATGTGTCTGACCTCAGGCCTTTTAGCCATATTTCAGTATGTGGCCTTTTTTGATGTTATGT
TTTATCCAGTAGCTTTACTAAGGTATAATTGATGTAATAAACTGCATATATTTAAAGTGTATACTTTGACAAATTTTGACATGGTGTATA
CCTTCGAAACTATGCCACAGTCTGGATGTGTTTACTGAAACATTTTAATAAGGAAGTTTATTTTTGATAAAGTTATGTTTTTGGATACAA
TATATTTGTATGGTGAGAGTGATGAATTGTTGGATCATTTGAATAAAATCTTTTACTAACCCCATGATAAAAGGAGAAGACAACAGTGAG
CTTAGAATATCTATAAAGCAAAAAATGTAGTCTCTTGTTTAAAAAATCTGGAGCGGGAATGCAAGGATACAAAACTTTAGCATGCTTTGA
GCAAAAATTTAAACTTACTGGAATCTTTTATAATAATGTAAGTGGAATGGAGGATTCTAGGAACTGAGAACTGTATTGGAATAGGTTCAA
AATATGTAAGAAATGCTAATGTGGGAGATAAAAATTTTATTTAGTACTTATTCTGATTATTATTAAAGTAATAATGTGTTCCTTGAGGAT
AACTTGTCAAATGCCCCAAAGCATAAAGAATATAATTCTGAATCCCAAATTCCAAAGACAAGAACTCTGTGTTTGAATTCATTCTGCATA
TAATTATTTATAAGTATAGATTGTGAATTTTTCCATGTTCTTAAAATTATTTTTATCTTTTTTCATGGTTGCATAGTGCTCCATTGTTTG
GCCTTGGTAATATTTAGTTGATAATTCCATTACTGTGTATTTTTCACTTGTTTCTAAGATCAAACATTTTAATATGTGCATGTTATATAT
AAATATGTAAATTCTGTGATACTCTATGATCATCTCTTTCTTTATATTATTTTCATAGACATGAAATAGTTGCTCAGAGATTATGCATTT
TAAGACACTCATAGTATATATTGCCAAAGTGGTTTCCAGAAAGGCACTGCTGGCTTCGACTCCTATAAGCAGCACGTGGGCTTGTTCATC
TCACTGCATGTTTATGAAGATACAGTTCTTTTGCCTTGTTCTCTGCCTGATGTGTATGCAGAGGCAGCCCTCAATATGCAGTGGTTGAAT

>15725_15725_4_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000377534_length(amino acids)=287AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------
>15725_15725_5_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000465261_length(transcript)=2173nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGTGTGTTGCCTGTGAGTGTGACCTCGGAGGCTCTTC
CTCAGGAGCTGAAGTCAGGATCAGAAACCACCAACTGTACTGCAACGACTGCTATCTCAGATTCAAATCTGGACGGCCAACCGCCATGTG
ATGTAAGCCTCCATACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAAATATGTGTTGTATGTCTTT
TTTGCTTTTTTTTTAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTGGTAGAACCAGTATTTTTGT
TGTTTATTTATAAGGTAATTGTGTGTGGGGAAAAGTGCAGTATTTACCTGTTGAATTCAGCATCTTGAGAGCACAAGGGAAAAAATAAGA
ACCTACGAATATTTTTGAGGCAGATAATGATCTAGTTTGACTTTCTAGTTAGTGGTGTTTTGAAGAGGGTATTTTATTGTTTTTTAAAAA
AAGGTTCTTAAACATTATTTGAAATAGTTAATATAAATACATAATTGCATTTGCTCTGTTTATTGTAATGTATTCTAAATTAATGCAGAA
CCATATGGAAAATTTCATTAAAATCTATCCCCAAATGTGCTTTCTGTATCCTTCCTTCTACCTATTATTCTGATTTTTAAAAATGCAGTT
AATGTACCATTTATTTGCTTGATGAAGGGAGCTCTATTTTCTTTACCAGAAATGTTGCTAAGTAATTCCCAATAGAAAGCTGCTTATTTT
CATTAATGAAAAATAACCATGGTTTGTATACTAGAAGTCTTCTTCAGAAACTGGTGAGCCTTTCTGTTCAATTGCATTTGTAAATAAACT

>15725_15725_5_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000465261_length(amino acids)=343AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------
>15725_15725_6_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000526202_length(transcript)=1763nt_BP=804nt
GCCTCCGTCACCTCCCCCTCAACGACTGCAAAAGAGCCTAAACCAAAATCCCCTAGTTTCTATTGAACACTATCGCTGTGTGTACCAATT
CCTGGACTAGGTCGGCGTAAGAGAGGAAGTAGGTGAAAAAAATAAAGAGGCGCTCCCCTCCACGTGATCCCAGCCCTGCCTCTTTAGTGA
GGCACGCGGCCGGGCGGCTCCAAGGCTGCCGGCTAGGGTGAGCAGCGGAGCGCTTGGGCTTGGAGTAGCAAAGAACGCGCTCTCCAGAGA
AAGTATAGCCACTGCTTAGACAGCCAGGGAAACGTGTGCGGGGAAGTGGAGGACTCAGGCTCTCGTGCGAGAGCGGAGTTGGACGTGCAG
GGCCGCTGGGGTCACGCGGAGCTCTCCCGCCTCCCCTCCGCGTGAGCTCTGGGATGGTCCGCGCCGGGAGCGCGCGCGAGGCTTGAAGCG
CGGGTGAAGCGCGCAGGTCGGAGTGACAGCTGCGCTGCCGGCCCGGCTGCGGTCAGCAACGCGCCATGGACGCAGAGCTGGCAGAGGTGC
GCGCCTTGCAAGCTGAGATCGCGGCCCTGCGGCGAGCGTGTGAGGACCCACCGGCGCCCTGGGAAGAGAAGTCCCGAGTCCAAAAATCTT
TTCAAGCCATACACCAATTCAATTTGGAAGGATGGAAGTCTTCAAAAGATCTGAAAAATCAGCTTGGACATTTAGAATCAGAACTTTCAT
TTCTAAGTACGCTTACTGGCATCAATATAAGAAATCACTCCAAGCAGACAGAAGACCTAACAAGCACTGAGATGACAGAAAAGAGAAACA
ATAAATATTTAGACCAAATTGGGAACATGACCTCTTCACAGAGGAGATCCAAGAAAGAACAAGTACCATCAGGAGCAGAATTGGAGAGGC
AACAAATCCTTCAGGAAATGAGGAAGAGAACACCCCTTCACAATGACAACAGCTGGATCCGACAGCGCAGTGCCAGTGTCAACAAAGAGC
CTGTTAGTCTTCCTGGGATCATGAGAAGAGGCGAATCTTTAGATAACCTGGACTCCCCCCGATCCAATTCTTGGAGACAGCCTCCTTGGC
TCAATCAGCCCACAGGATTCTATGCTTCTTCCTCTGTGCAAGACTTTAGTCGCCCACCACCTCAGCTGGTGTCCACATCAAACCGTGCCT
ACATGCGGAACCCCTCCTCCAGCGTGCCCCCACCTTCAGCTGGCTCCGTGAAGACCTCCACCACAGGTGTGGCCACCACACAGTCCCCCA
CCCCGAGAAGCCATTCCCCTTCAGCTTCACAGTCAGGCTCTCAGCTGCGTAACAGGTCAGTCAGTGGGAAGCGCATATGCTCCTACTGCA
ATAACATTCTGGGCAAAGGAGCCGCCATGATCATCGAGTCCCTGGGTCTTTGTTATCATTTGCATTGTTTTAAGTGTGTTGCCTGTGAGT
GTGACCTCGGAGGCTCTTCCTCAGGAGCTGAAGTCAGGATCAGAAACCACCAACTGTACTGCAACGACTGCTATCTCAGATTCAAATCTG
GACGGCCAACCGCCATGTGATGTAAGCCTCCATACGAAAGCACTGTTGCAGATAGAAGAAGAGGTGGTTGCTGCTCATGTAGATCTATAA
ATATGTGTTGTATGTCTTTTTTGCTTTTTTTTTAAAAAAAAGAATAACTTTTTTTGCCTCTTTAGATTACATAGAAGCATTGTAGTCTTG

>15725_15725_6_CENPP-LMO7_CENPP_chr9_95094633_ENST00000375587_LMO7_chr13_76423214_ENST00000526202_length(amino acids)=356AA_BP=109
MRCRPGCGQQRAMDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINI
RNHSKQTEDLTSTEMTEKRNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR
GESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSAS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CENPP-LMO7

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CENPP-LMO7

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CENPP-LMO7

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source