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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CEP85L-HDAC2 (FusionGDB2 ID:15913)

Fusion Gene Summary for CEP85L-HDAC2

Fusion gene summary

Fusion gene information	Fusion gene name: CEP85L-HDAC2
	Fusion gene ID: 15913
		Hgene	Tgene
	Gene symbol	CEP85L	HDAC2
	Gene ID	387119	3066
	Gene name	centrosomal protein 85 like	histone deacetylase 2
	Synonyms	C6orf204\|NY-BR-15\|bA57K17.2	HD2\|KDAC2\|RPD3\|YAF1
	Cytomap	6q22.31	6q21
	Type of gene	protein-coding	protein-coding
	Description	centrosomal protein of 85 kDa-likecentrosomal protein 85kDa-likeserologically defined breast cancer antigen NY-BR-15	histone deacetylase 2YY1-associated factor 1transcriptional regulator homolog RPD3
	Modification date	20200313	20200322
	UniProtAcc	Q5SZL2	Q92769
	Ensembl transtripts involved in fusion gene	ENST00000368488, ENST00000368491, ENST00000392500, ENST00000419517, ENST00000360290, ENST00000472713,	ENST00000368632, ENST00000519108, ENST00000398283, ENST00000519065,
Fusion gene scores	* DoF score	10 X 10 X 6=600	6 X 5 X 2=60
	# samples	11	6
	** MAII score	log2(11/600*10)=-2.44745897697122 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/60*10)=0
Context	PubMed: CEP85L [Title/Abstract] AND HDAC2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CEP85L(118953616)-HDAC2(114281182), # samples:1
Anticipated loss of major functional domain due to fusion event.	CEP85L-HDAC2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. CEP85L-HDAC2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. CEP85L-HDAC2 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across CEP85L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HDAC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-IN-7808-01A	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-

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Fusion Gene ORF analysis for CEP85L-HDAC2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000368488	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000368488	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000368491	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000368491	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000392500	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000392500	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000419517	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5CDS-5UTR	ENST00000419517	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5UTR-3CDS	ENST00000360290	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5UTR-3CDS	ENST00000360290	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5UTR-5UTR	ENST00000360290	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
5UTR-5UTR	ENST00000360290	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
Frame-shift	ENST00000368488	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
Frame-shift	ENST00000368488	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
Frame-shift	ENST00000392500	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
Frame-shift	ENST00000392500	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
In-frame	ENST00000368491	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
In-frame	ENST00000368491	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
In-frame	ENST00000419517	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
In-frame	ENST00000419517	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
intron-3CDS	ENST00000472713	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
intron-3CDS	ENST00000472713	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
intron-5UTR	ENST00000472713	ENST00000368632	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-
intron-5UTR	ENST00000472713	ENST00000519108	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000368491	CEP85L	chr6	118953616	-	ENST00000519065	HDAC2	chr6	114281182	-	10299	854	511	2268	585
ENST00000368491	CEP85L	chr6	118953616	-	ENST00000398283	HDAC2	chr6	114281182	-	7171	854	511	2268	585
ENST00000419517	CEP85L	chr6	118953616	-	ENST00000519065	HDAC2	chr6	114281182	-	10265	820	477	2234	585
ENST00000419517	CEP85L	chr6	118953616	-	ENST00000398283	HDAC2	chr6	114281182	-	7137	820	477	2234	585

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000368491	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-	0.000125297	0.9998747
ENST00000368491	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-	0.000150607	0.9998493
ENST00000419517	ENST00000519065	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-	0.000125921	0.9998741
ENST00000419517	ENST00000398283	CEP85L	chr6	118953616	-	HDAC2	chr6	114281182	-	0.000153877	0.9998461

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Fusion Genomic Features for CEP85L-HDAC2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CEP85L-HDAC2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:118953616/chr6:114281182)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CEP85L Q5SZL2	HDAC2 Q92769
FUNCTION: Plays an essential role in neuronal cell migration. {ECO:0000269\|PubMed:32097630}.	FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. Involved in MTA1-mediated transcriptional corepression of TFF1 and CDKN1A. {ECO:0000269\|PubMed:19343227, ECO:0000269\|PubMed:21965678}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

HDAC2

chr6:118953616

chr6:114281182

ENST00000519065

300_303

489.0

Compositional bias

Note=Poly-Gly

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CEP85L

chr6:118953616

chr6:114281182

ENST00000360290

439_682

395.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CEP85L

chr6:118953616

chr6:114281182

ENST00000368488

439_682

809.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CEP85L

chr6:118953616

chr6:114281182

ENST00000368491

439_682

806.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CEP85L

chr6:118953616

chr6:114281182

ENST00000392500

439_682

500.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CEP85L

chr6:118953616

chr6:114281182

ENST00000419517

439_682

497.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

HDAC2

chr6:118953616

chr6:114281182

ENST00000519065

9_322

489.0

Region

Note=Histone deacetylase

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Fusion Gene Sequence for CEP85L-HDAC2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>15913_15913_1_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000368491_HDAC2_chr6_114281182_ENST00000398283_length(transcript)=7171nt_BP=854nt
GGGAGGGCGTGAGGGATTACCCAAGGGAGGGGCGAGTATCGCAAAATAGGCCAAGTCGCTGCCCTCTACTCAACTCGCAGGGCGGGAGGA
TGGAGACAGAGGGATGCGGCGGGAGGGCGGGACAGCCCAGTCGCCGCCAAGGAGGCGAAGCGGGGTCGGGGTAGCTCACCCGCCCCCCGC
AGTCCCCGCCCCCCGCAGTCCCCGCCCCGCGCGGCGCCGCGCACGCCTGAAGTCATTGCCCGAGGCCCCGCCCCCTCGCGGCCCCAGCCC
CGGCTCTGGCTCTGCCGGCGGAGGGGGCGGAGAGAACCCGCAGCTGCAACTTCGCCTGGAGCCTTTGAGCCTGGGCTCAGCCGGGGATCT
AGCAGCCGTCACCGCCGAGTCGCCGCTTCCCCGGCGCGGGCCTCAGCCCAGCCGGCTTGGCCATGGCAGGCGCCGGCAGTGCGGCGAATC
TGGCCCCTGCGCTCCCCGCCCGTAGCTGAGCAGCCGTTAACCAGCCATCCCGCCTTTCCTCCTGCCCGTGTCGCCGAGGCCCACGCTCCG
CGCAAGTTTCCGCCGCCGAAGAAGCAGGAGGACGGACGTGAGGAGTCGGGCGTCCCTGGCCCACCCGGCCCTCTCGCCCGCGATGTGGGG
GCGCTTCCTGGCTCCGGAGGCCAGCGGCCGGGATAGCCCCGGCGGAGCCCGCAGCTTCCCTGCCGGCCCAGATTATTCATCAGCATGGCT
ACCTGCTAATGAATCATTGTGGCAGGCCACAACTGTTCCATCTAACCATCGAAATAACCATATCAGGAGACACAGTATAGCTTCTGACAG
TGGAGACACTGGCATTGGAACTTCCTGTTCTGATAGCGTGGAAGGTGATATTGGAAATTATTATTATGGACAGGGTCATCCCATGAAGCC
TCATAGAATCCGCATGACCCATAACTTGCTGTTAAATTATGGCTTATACAGAAAAATGGAAATATATAGGCCCCATAAAGCCACTGCCGA
AGAAATGACAAAATATCACAGTGATGAGTATATCAAATTTCTACGGTCAATAAGACCAGATAACATGTCTGAGTATAGTAAGCAGATGCA
GAGATTTAATGTTGGAGAAGATTGTCCAGTGTTTGATGGACTCTTTGAGTTTTGTCAGCTCTCAACTGGCGGTTCAGTTGCTGGAGCTGT
GAAGTTAAACCGACAACAGACTGATATGGCTGTTAATTGGGCTGGAGGATTACATCATGCTAAGAAATCAGAAGCATCAGGATTCTGTTA
CGTTAATGATATTGTGCTTGCCATCCTTGAATTACTAAAGTATCATCAGAGAGTCTTATATATTGATATAGATATTCATCATGGTGATGG
TGTTGAAGAAGCTTTTTATACAACAGATCGTGTAATGACGGTATCATTCCATAAATATGGGGAATACTTTCCTGGCACAGGAGACTTGAG
GGATATTGGTGCTGGAAAAGGCAAATACTATGCTGTCAATTTTCCAATGAGAGATGGTATAGATGATGAGTCATATGGGCAGATATTTAA
GCCTATTATCTCAAAGGTGATGGAGATGTATCAACCTAGTGCTGTGGTATTACAGTGTGGTGCAGACTCATTATCTGGTGATAGACTGGG
TTGTTTCAATCTAACAGTCAAAGGTCATGCTAAATGTGTAGAAGTTGTAAAAACTTTTAACTTACCATTACTGATGCTTGGAGGAGGTGG
CTACACAATCCGTAATGTTGCTCGATGTTGGACATATGAGACTGCAGTTGCCCTTGATTGTGAGATTCCCAATGAGTTGCCATATAATGA
TTACTTTGAGTATTTTGGACCAGACTTCAAACTGCATATTAGTCCTTCAAACATGACAAACCAGAACACTCCAGAATATATGGAAAAGAT
AAAACAGCGTTTGTTTGAAAATTTGCGCATGTTACCTCATGCACCTGGTGTCCAGATGCAAGCTATTCCAGAAGATGCTGTTCATGAAGA
CAGTGGAGATGAAGATGGAGAAGATCCAGACAAGAGAATTTCTATTCGAGCATCAGACAAGCGGATAGCTTGTGATGAAGAATTCTCAGA
TTCTGAGGATGAAGGAGAAGGAGGTCGAAGAAATGTGGCTGATCATAAGAAAGGAGCAAAGAAAGCTAGAATTGAAGAAGATAAGAAAGA
AACAGAGGACAAAAAAACAGACGTTAAGGAAGAAGATAAATCCAAGGACAACAGTGGTGAAAAAACAGATACCAAAGGAACCAAATCAGA
ACAGCTCAGCAACCCCTGAATTTGACAGTCTCACCAATTTCAGAAAATCATTAAAAAGAAAATATTGAAAGGAAAATGTTTTCTTTTTGA
AGACTTCTGGCTTCATTTTATACTACTTTGGCATGGACTGTATTTATTTTCAAATGGCTTTTTCGTTTTTGTTTTTCTTGGCAAGTTTTA
TTGTGAGTTTTTCTAATTATGAAGCAAAATTTCTTTTCTCCACCATGCTTTATGTGATAGTATTTAAAATTGATGTGAGTTATTATGTCA
AAAAAACTGATCTATTAAAGAAGTAATTGGCCTTTCTGAGCTGATTTTTCCATCTTTTGTAATTATCTTTATTAAAAAATTGTACTTGGA
TTATCTTTTGTCTGTTTATTACTACAATATGAAGTCTTGTTTCAGTGGCTAATGACATCATTTCTGTAGACTTACAATACACTCTAGGTG
AAAGATAATGATTACAGCTTGAAAGATAACTATTTGCTGTTTCTTTGGGAAGAGTATTTATAGTAATTATTACTTATCTTTGCAATAGAA
ATTCTACCACCTTGCCCTCTATAGCTTAGCCAGTTAGTATCAGTGAAGATTAACATCCCATTACAATTTATGAAATAATACAGACTCTGC
AATTGAGATGTAGGAGTTCTTTGAGTTGACCCAAAGATTCTCAAAATTGAAATGGAAATTCTGAATTGAAAGAAGAAACTGACCAGAACT
TGTATTGACCAGACTTGCCTATAGTATATTGCTGGTTTAAAATGGAACCTGCAGACAAAACCTGTTTCTTTTACTGCATTTACATGGCAT
CCAGGTTCCATTATTATTTACGTGACATCCAGGTTTCTAACTCAAGGAAATAAACACAACTGATTTATCATTCAGCAACTACTTATTGTG
TGTCTGCCCATTTTAAGACTGTAGGAGTGTAACTGAATATAATGGAAAAATGCTTTCACTCAGAGCTTACACTCAGAGCTTACATTCTAG
TAGCAGGAAGCAGACAAATGGGGGTAACTCCTGCTACTAAGATGTGCAAAGAAGACAAAACATTTTAGGAACTTGCCAAAATCAGTGAAA
TCTCCCTTTTTGTCAGGCCCACATTGATTCTTTTGAGATTAAAAATTACAGAATGCCAGAAGATAATTCAGTCAAAAGTATTTCTCTTCA
GTGCAGTAAAATATTAAAAGAAAAAATATTTCTCTACAAGCCTCTTAAATGTTTCAGACATTCACAATAGCACCTAGACTTTTGTAATGA
ACAGCTGTGCACCCACCCCGACTTAACAAATATTTTACTTTTGCTATATTTGCTTCGGTGTTTTTTTCTTAAAATACACCGAAATTGAAG
CTCTCTTTGTGTACTTTGTCGTTTGTAATCCTCCCTCCCTCCCAGCCTTAAGAAGTAATCACCATTGTGATTATTTTATCCATGTTTTTG
TGAATATTTTACCCATGTTTTTGTACTTTTGCTACATATTTGTTATCAATCTGTAAACCTTTATGACATTAGGAACTAAGAAACTTAGTC
CCTTCGTTAGGGGGATAATGAAATGTATTTAGTGTTTGTGAAACATAGATGGTATGTATTTGGACAATTCTGTAACTTTGCTTTTTTTAT
TTTTATTTTTCCATAGCTTATTGGGGAACAGGTGGTGTTTGGTTACATGATTAAGTTCTTTAGTGGTGATTTGTGGGATTTTGGTGGACC
CATCACCCAAGCAGTGTACACTGCACCCTATTTGTAATCTTTTATCCCTCGCCCCCCTCCCACCATGCCTCCCGTCTACCATGATGATCC
TGTTTTAAATAAGAAAATACCATTTCGCAGGCTCCAGATGTTCTGGCATCCTCCCTGTGGATTTCCCAGTGCCTGCAGCTCACAGGACAA
CAGGGGCTGTGGTAGAGTCACCTATGAGATCCTGGAGTAGTGGATGGAGGAGATGGAACAGTGAAGACGGAAACTGAGCTCAGTATCCGG
GTGCCAGGAGACAAAGGCCCTTTGCTTTTTTTCATTTAATATTCTGATCTACCCCTGTTGACACATGTTAAGTATAGTTCATTTTGACTG
CTATGTATTATGTTCCATTGTGTGAACATACTGAAATTGTACACTTCAATACTATACTGGATCTCCTTGGGTGTATTTAAGAGGTTTTGT
TTTTCTAAGTAGTTGGTTATATACAACTAAAACCTCAAGAGAACTATCTAAAGCAATTTCAGCAAGGTGATTTGGTACAGCATTAATAAA
CAGAAATCAGTAACACTTAGTGACCAAGTCTGTTGGAAGAACAAAGACCCCCATTTGTAATAACAAAATTTTTAGAAATAATATGTAAAG
AAGCTATGGTTCTTGTGTCTAGTAAGGTCAATGTAACATAGTAAGATGTCAGAATACCCTAATACTTTAAAAAATTCATATAGGATAAAA
ATGATATTTGAAATTGGCAAGGAAAGACATTATTTTGTAAGTGGAATTGGGACAACAACTGGTAACCAAATGGAAAACCCAGTTTTCTGC
CCTCCACTAGAAGATTTAAATAGGAAAAGATAAAACTACCAAAAACCTAAACTCTTAAAGCAAATGGATTGAAGAAGGCCTAAGTGTGAC
ACCAAACTCAACTATAAAAGATATATTTGATAACAAAAAAAAAATTAGTTCAGTGGACCAACAAAAACTTAGAAGACAAGTCAAGAAAAA
TGACAAAAGACAGAGTGGGAGGCAGATTTGTAACTCATCCAGGTCAAAAGGCTCATATCTAAAGATAGTAGAGGAACAAAATGTATAAGG
ATGTGAACTGGGAAACAAATACATATAAATAGTTTGTAAATATGAAAAGATCTTTAACCTCAGTAAATAAAAAGCTATAGAGAGACTTAT
TTTTTAACTTAGTTTTTTAAACCTATTATGTTTATTTATTTTTTCTTTTTTTGAGACGGAGTCTCGCTGTTGCCCAGGCTGGTGTGCAAT
GGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGAAGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCC
TGTCACCACGCCCAGCTAATTGTTCGCATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCTCATG
ATCCACCCACCTTGGCCTTCCAAAGTGCTGGGATTACAGGTGTGAGCTGCCGCACCTGGCTGTTTATCTCTTTTTTTTAGAGAAAGGATC
TCGGTCACCCAGGATGGAGTGTGGTAGCCTGATCATATCTCACTACATCTTAGAACTTCTAGGCTTAGGGTATTCTCCCACCTCAGCCTC
CCAAGTAGCTGGGACTACAAGTGTGCACCATCACACCTAGCTGATTTTTACATTTTTATTTTGGAGAGATGGTGTCTCCCTGTGTTGCCC
AGGCTGGTCACAAACTCCTAGGCTCAAGCGATTCTCCTGACTCAGGCATGAGCCACCGTACCCGGCCTAAACCTATCATGTTACAGACTT
AGAAAGCAACTATTGTCAAGTGTTTGAGGAAACTCAGGTCAGGTTTGGTAAACTAAGATATTAACTCAAGTAAAGCTCTTTAATTCATTT
AATGAAGGTGCCACATTGTCTCAGTTCTCTATGGCATGGGTGAATGCTGTTCTAAGTCAGCATTGGTACTCTAAGCTAGTTACATCATAT
CTAAGCTTTGCCCTTCTACCAGAGCTGCTAGCATTCTGTCAATGGGCAATTATTTGAAGTTCTTACATTGAAGTTAGTCACCTACATCTT
CTGTTTTTTATGGTTTTGATGTAGTAATACTGCTGAAGTTTTTTTGATAACTGCGATTCATAATATTTGTTATTCATATTGTGATATAAA
TGATAAGGGCTTTTGAAAACAAGTAGTAATCATTTCAATAGCTTAGGATCTCCACCATAATCTTAGGAAAATTACTAACCTCTGTGCCTC
AGTTGCTTCATCATTTAAAATGAGGAAAATAATAGTCCCTACTTAATAGGTTTGTTGTGAGGATTGAGTTAATAACATAGTTAATGCTCA
GTAAGGGTTAGCTGCTATTTTTTTTTCTTTTTTTTTTGAAAGAGTCTCACTCTGTTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCT
CACTGCATCCTCTGCTTCCTAGGTTCAGGTGATTCTCATGCTTCAGCCTCCCAAGCAGCTGGGAGTACAGGTGTGCACCACCACACCTGG
CTAATTTTTGTATATTTAGTAGAGACGGGTTCTCACCATATTGTCCAGGCTGGTCTTGAACTCCTTACCTCAAATGATCCACCCGCCTGG
GCCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCGCGCCTGGCTTGCTATTGTTATGAGGTAAAGGTAGATAGATGGGTGAGAGTGG
TGCCAGGGGAAGTGTTAAATTTTTGAGTGTTCCTTTAGATGCCAGATGGGTTGTATCTGAGCCTTTTATTGCAGTTTGATGCCTACTAGT
GTGAAGACTACTAGGTCATAGTGGATAGAGAAGCAATCTTTTGGAGACCTGATTTTAGCAAGGATACGAATAATATTTGACAACTTTGGG
GGGATCTTGATGCCTCTGTAATTTACTCAAGGATAATCTCAAGAAAAATGGCATTAAGTAGATTACAGAAAAAATAGAACTATCATATTG
TTATTATTGGCTATTTACATGAGCAATGCGGAGAAATGTTTAGGATTACAGCATTTAGAAGCTTCTCAATTGCTGCATTTCCTCACTGTA
CCACAAGATGGCAGATACTGCATTTAAAATTTTTTTTTCTGTGTGTTTTCTCTTATAGTCACTTGGTGGCCATGTAACAAGCAGAGCAAC

>15913_15913_1_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000368491_HDAC2_chr6_114281182_ENST00000398283_length(amino acids)=585AA_BP=114
MPVSPRPTLRASFRRRRSRRTDVRSRASLAHPALSPAMWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNH
IRRHSIASDSGDTGIGTSCSDSVEGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPD
NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLY
IDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCG
ADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTN
QNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAK

--------------------------------------------------------------
>15913_15913_2_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000368491_HDAC2_chr6_114281182_ENST00000519065_length(transcript)=10299nt_BP=854nt
GGGAGGGCGTGAGGGATTACCCAAGGGAGGGGCGAGTATCGCAAAATAGGCCAAGTCGCTGCCCTCTACTCAACTCGCAGGGCGGGAGGA
TGGAGACAGAGGGATGCGGCGGGAGGGCGGGACAGCCCAGTCGCCGCCAAGGAGGCGAAGCGGGGTCGGGGTAGCTCACCCGCCCCCCGC
AGTCCCCGCCCCCCGCAGTCCCCGCCCCGCGCGGCGCCGCGCACGCCTGAAGTCATTGCCCGAGGCCCCGCCCCCTCGCGGCCCCAGCCC
CGGCTCTGGCTCTGCCGGCGGAGGGGGCGGAGAGAACCCGCAGCTGCAACTTCGCCTGGAGCCTTTGAGCCTGGGCTCAGCCGGGGATCT
AGCAGCCGTCACCGCCGAGTCGCCGCTTCCCCGGCGCGGGCCTCAGCCCAGCCGGCTTGGCCATGGCAGGCGCCGGCAGTGCGGCGAATC
TGGCCCCTGCGCTCCCCGCCCGTAGCTGAGCAGCCGTTAACCAGCCATCCCGCCTTTCCTCCTGCCCGTGTCGCCGAGGCCCACGCTCCG
CGCAAGTTTCCGCCGCCGAAGAAGCAGGAGGACGGACGTGAGGAGTCGGGCGTCCCTGGCCCACCCGGCCCTCTCGCCCGCGATGTGGGG
GCGCTTCCTGGCTCCGGAGGCCAGCGGCCGGGATAGCCCCGGCGGAGCCCGCAGCTTCCCTGCCGGCCCAGATTATTCATCAGCATGGCT
ACCTGCTAATGAATCATTGTGGCAGGCCACAACTGTTCCATCTAACCATCGAAATAACCATATCAGGAGACACAGTATAGCTTCTGACAG
TGGAGACACTGGCATTGGAACTTCCTGTTCTGATAGCGTGGAAGGTGATATTGGAAATTATTATTATGGACAGGGTCATCCCATGAAGCC
TCATAGAATCCGCATGACCCATAACTTGCTGTTAAATTATGGCTTATACAGAAAAATGGAAATATATAGGCCCCATAAAGCCACTGCCGA
AGAAATGACAAAATATCACAGTGATGAGTATATCAAATTTCTACGGTCAATAAGACCAGATAACATGTCTGAGTATAGTAAGCAGATGCA
GAGATTTAATGTTGGAGAAGATTGTCCAGTGTTTGATGGACTCTTTGAGTTTTGTCAGCTCTCAACTGGCGGTTCAGTTGCTGGAGCTGT
GAAGTTAAACCGACAACAGACTGATATGGCTGTTAATTGGGCTGGAGGATTACATCATGCTAAGAAATCAGAAGCATCAGGATTCTGTTA
CGTTAATGATATTGTGCTTGCCATCCTTGAATTACTAAAGTATCATCAGAGAGTCTTATATATTGATATAGATATTCATCATGGTGATGG
TGTTGAAGAAGCTTTTTATACAACAGATCGTGTAATGACGGTATCATTCCATAAATATGGGGAATACTTTCCTGGCACAGGAGACTTGAG
GGATATTGGTGCTGGAAAAGGCAAATACTATGCTGTCAATTTTCCAATGAGAGATGGTATAGATGATGAGTCATATGGGCAGATATTTAA
GCCTATTATCTCAAAGGTGATGGAGATGTATCAACCTAGTGCTGTGGTATTACAGTGTGGTGCAGACTCATTATCTGGTGATAGACTGGG
TTGTTTCAATCTAACAGTCAAAGGTCATGCTAAATGTGTAGAAGTTGTAAAAACTTTTAACTTACCATTACTGATGCTTGGAGGAGGTGG
CTACACAATCCGTAATGTTGCTCGATGTTGGACATATGAGACTGCAGTTGCCCTTGATTGTGAGATTCCCAATGAGTTGCCATATAATGA
TTACTTTGAGTATTTTGGACCAGACTTCAAACTGCATATTAGTCCTTCAAACATGACAAACCAGAACACTCCAGAATATATGGAAAAGAT
AAAACAGCGTTTGTTTGAAAATTTGCGCATGTTACCTCATGCACCTGGTGTCCAGATGCAAGCTATTCCAGAAGATGCTGTTCATGAAGA
CAGTGGAGATGAAGATGGAGAAGATCCAGACAAGAGAATTTCTATTCGAGCATCAGACAAGCGGATAGCTTGTGATGAAGAATTCTCAGA
TTCTGAGGATGAAGGAGAAGGAGGTCGAAGAAATGTGGCTGATCATAAGAAAGGAGCAAAGAAAGCTAGAATTGAAGAAGATAAGAAAGA
AACAGAGGACAAAAAAACAGACGTTAAGGAAGAAGATAAATCCAAGGACAACAGTGGTGAAAAAACAGATACCAAAGGAACCAAATCAGA
ACAGCTCAGCAACCCCTGAATTTGACAGTCTCACCAATTTCAGAAAATCATTAAAAAGAAAATATTGAAAGGAAAATGTTTTCTTTTTGA
AGACTTCTGGCTTCATTTTATACTACTTTGGCATGGACTGTATTTATTTTCAAATGGCTTTTTCGTTTTTGTTTTTCTTGGCAAGTTTTA
TTGTGAGTTTTTCTAATTATGAAGCAAAATTTCTTTTCTCCACCATGCTTTATGTGATAGTATTTAAAATTGATGTGAGTTATTATGTCA
AAAAAACTGATCTATTAAAGAAGTAATTGGCCTTTCTGAGCTGATTTTTCCATCTTTTGTAATTATCTTTATTAAAAAATTGTACTTGGA
TTATCTTTTGTCTGTTTATTACTACAATATGAAGTCTTGTTTCAGTGGCTAATGACATCATTTCTGTAGACTTACAATACACTCTAGGTG
AAAGATAATGATTACAGCTTGAAAGATAACTATTTGCTGTTTCTTTGGGAAGAGTATTTATAGTAATTATTACTTATCTTTGCAATAGAA
ATTCTACCACCTTGCCCTCTATAGCTTAGCCAGTTAGTATCAGTGAAGATTAACATCCCATTACAATTTATGAAATAATACAGACTCTGC
AATTGAGATGTAGGAGTTCTTTGAGTTGACCCAAAGATTCTCAAAATTGAAATGGAAATTCTGAATTGAAAGAAGAAACTGACCAGAACT
TGTATTGACCAGACTTGCCTATAGTATATTGCTGGTTTAAAATGGAACCTGCAGACAAAACCTGTTTCTTTTACTGCATTTACATGGCAT
CCAGGTTCCATTATTATTTACGTGACATCCAGGTTTCTAACTCAAGGAAATAAACACAACTGATTTATCATTCAGCAACTACTTATTGTG
TGTCTGCCCATTTTAAGACTGTAGGAGTGTAACTGAATATAATGGAAAAATGCTTTCACTCAGAGCTTACACTCAGAGCTTACATTCTAG
TAGCAGGAAGCAGACAAATGGGGGTAACTCCTGCTACTAAGATGTGCAAAGAAGACAAAACATTTTAGGAACTTGCCAAAATCAGTGAAA
TCTCCCTTTTTGTCAGGCCCACATTGATTCTTTTGAGATTAAAAATTACAGAATGCCAGAAGATAATTCAGTCAAAAGTATTTCTCTTCA
GTGCAGTAAAATATTAAAAGAAAAAATATTTCTCTACAAGCCTCTTAAATGTTTCAGACATTCACAATAGCACCTAGACTTTTGTAATGA
ACAGCTGTGCACCCACCCCGACTTAACAAATATTTTACTTTTGCTATATTTGCTTCGGTGTTTTTTTCTTAAAATACACCGAAATTGAAG
CTCTCTTTGTGTACTTTGTCGTTTGTAATCCTCCCTCCCTCCCAGCCTTAAGAAGTAATCACCATTGTGATTATTTTATCCATGTTTTTG
TGAATATTTTACCCATGTTTTTGTACTTTTGCTACATATTTGTTATCAATCTGTAAACCTTTATGACATTAGGAACTAAGAAACTTAGTC
CCTTCGTTAGGGGGATAATGAAATGTATTTAGTGTTTGTGAAACATAGATGGTATGTATTTGGACAATTCTGTAACTTTGCTTTTTTTAT
TTTTATTTTTCCATAGCTTATTGGGGAACAGGTGGTGTTTGGTTACATGATTAAGTTCTTTAGTGGTGATTTGTGGGATTTTGGTGGACC
CATCACCCAAGCAGTGTACACTGCACCCTATTTGTAATCTTTTATCCCTCGCCCCCCTCCCACCATGCCTCCCGTCTACCATGATGATCC
TGTTTTAAATAAGAAAATACCATTTCGCAGGCTCCAGATGTTCTGGCATCCTCCCTGTGGATTTCCCAGTGCCTGCAGCTCACAGGACAA
CAGGGGCTGTGGTAGAGTCACCTATGAGATCCTGGAGTAGTGGATGGAGGAGATGGAACAGTGAAGACGGAAACTGAGCTCAGTATCCGG
GTGCCAGGAGACAAAGGCCCTTTGCTTTTTTTCATTTAATATTCTGATCTACCCCTGTTGACACATGTTAAGTATAGTTCATTTTGACTG
CTATGTATTATGTTCCATTGTGTGAACATACTGAAATTGTACACTTCAATACTATACTGGATCTCCTTGGGTGTATTTAAGAGGTTTTGT
TTTTCTAAGTAGTTGGTTATATACAACTAAAACCTCAAGAGAACTATCTAAAGCAATTTCAGCAAGGTGATTTGGTACAGCATTAATAAA
CAGAAATCAGTAACACTTAGTGACCAAGTCTGTTGGAAGAACAAAGACCCCCATTTGTAATAACAAAATTTTTAGAAATAATATGTAAAG
AAGCTATGGTTCTTGTGTCTAGTAAGGTCAATGTAACATAGTAAGATGTCAGAATACCCTAATACTTTAAAAAATTCATATAGGATAAAA
ATGATATTTGAAATTGGCAAGGAAAGACATTATTTTGTAAGTGGAATTGGGACAACAACTGGTAACCAAATGGAAAACCCAGTTTTCTGC
CCTCCACTAGAAGATTTAAATAGGAAAAGATAAAACTACCAAAAACCTAAACTCTTAAAGCAAATGGATTGAAGAAGGCCTAAGTGTGAC
ACCAAACTCAACTATAAAAGATATATTTGATAACAAAAAAAAAATTAGTTCAGTGGACCAACAAAAACTTAGAAGACAAGTCAAGAAAAA
TGACAAAAGACAGAGTGGGAGGCAGATTTGTAACTCATCCAGGTCAAAAGGCTCATATCTAAAGATAGTAGAGGAACAAAATGTATAAGG
ATGTGAACTGGGAAACAAATACATATAAATAGTTTGTAAATATGAAAAGATCTTTAACCTCAGTAAATAAAAAGCTATAGAGAGACTTAT
TTTTTAACTTAGTTTTTTAAACCTATTATGTTTATTTATTTTTTCTTTTTTTGAGACGGAGTCTCGCTGTTGCCCAGGCTGGTGTGCAAT
GGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTGAAGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCC
TGTCACCACGCCCAGCTAATTGTTCGCATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCTCATG
ATCCACCCACCTTGGCCTTCCAAAGTGCTGGGATTACAGGTGTGAGCTGCCGCACCTGGCTGTTTATCTCTTTTTTTTAGAGAAAGGATC
TCGGTCACCCAGGATGGAGTGTGGTAGCCTGATCATATCTCACTACATCTTAGAACTTCTAGGCTTAGGGTATTCTCCCACCTCAGCCTC
CCAAGTAGCTGGGACTACAAGTGTGCACCATCACACCTAGCTGATTTTTACATTTTTATTTTGGAGAGATGGTGTCTCCCTGTGTTGCCC
AGGCTGGTCACAAACTCCTAGGCTCAAGCGATTCTCCTGACTCAGGCATGAGCCACCGTACCCGGCCTAAACCTATCATGTTACAGACTT
AGAAAGCAACTATTGTCAAGTGTTTGAGGAAACTCAGGTCAGGTTTGGTAAACTAAGATATTAACTCAAGTAAAGCTCTTTAATTCATTT
AATGAAGGTGCCACATTGTCTCAGTTCTCTATGGCATGGGTGAATGCTGTTCTAAGTCAGCATTGGTACTCTAAGCTAGTTACATCATAT
CTAAGCTTTGCCCTTCTACCAGAGCTGCTAGCATTCTGTCAATGGGCAATTATTTGAAGTTCTTACATTGAAGTTAGTCACCTACATCTT
CTGTTTTTTATGGTTTTGATGTAGTAATACTGCTGAAGTTTTTTTGATAACTGCGATTCATAATATTTGTTATTCATATTGTGATATAAA
TGATAAGGGCTTTTGAAAACAAGTAGTAATCATTTCAATAGCTTAGGATCTCCACCATAATCTTAGGAAAATTACTAACCTCTGTGCCTC
AGTTGCTTCATCATTTAAAATGAGGAAAATAATAGTCCCTACTTAATAGGTTTGTTGTGAGGATTGAGTTAATAACATAGTTAATGCTCA
GTAAGGGTTAGCTGCTATTTTTTTTTCTTTTTTTTTTGAAAGAGTCTCACTCTGTTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCT
CACTGCATCCTCTGCTTCCTAGGTTCAGGTGATTCTCATGCTTCAGCCTCCCAAGCAGCTGGGAGTACAGGTGTGCACCACCACACCTGG
CTAATTTTTGTATATTTAGTAGAGACGGGTTCTCACCATATTGTCCAGGCTGGTCTTGAACTCCTTACCTCAAATGATCCACCCGCCTGG
GCCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCGCGCCTGGCTTGCTATTGTTATGAGGTAAAGGTAGATAGATGGGTGAGAGTGG
TGCCAGGGGAAGTGTTAAATTTTTGAGTGTTCCTTTAGATGCCAGATGGGTTGTATCTGAGCCTTTTATTGCAGTTTGATGCCTACTAGT
GTGAAGACTACTAGGTCATAGTGGATAGAGAAGCAATCTTTTGGAGACCTGATTTTAGCAAGGATACGAATAATATTTGACAACTTTGGG
GGGATCTTGATGCCTCTGTAATTTACTCAAGGATAATCTCAAGAAAAATGGCATTAAGTAGATTACAGAAAAAATAGAACTATCATATTG
TTATTATTGGCTATTTACATGAGCAATGCGGAGAAATGTTTAGGATTACAGCATTTAGAAGCTTCTCAATTGCTGCATTTCCTCACTGTA
CCACAAGATGGCAGATACTGCATTTAAAATTTTTTTTTCTGTGTGTTTTCTCTTATAGTCACTTGGTGGCCATGTAACAAGCAGAGCAAC
ATGTATTAACAGATTCTTTTTGAATGCAATATTGGATTAAAAACTTTGAATTAAACTACAATTAAGTTTACTGATTTAGGTTTTCCTATA
AGAATTATAACACTAATTTCTAAGTTTTACATCTGCAAAACACAGTAGAGTGTATCTGGTAGTCATTGACTAATTGTGACTTTGCTAGTC
AGACAAAATGGAACTGAATATTAGAGCCAGAATAATTTTCTGTTTTGACTGGTGGTAAGAATCAGTTAGTATACAGAATGGGAAAGAATT
GAAATTTATTTCTAGGAATTATAGTTATAGTGAAGTTAATATTCAGGGGCATTGGGTGCTTGTTCCACGACTTTTGTTTACTGAACTAAG
TACCTAACCCCTTTGGTCTTTGAACACTGCAGAGTTATGATTAGGATTATTAATGAAAAATTCTTTTTTAGTAGAACAAACAGTTAAGGA
CAGAAGACACCTTGATTAGATTCTGTTATTTGCTCTTTTTATTAAGATTGTTTTTACTCTAAATGTTAAAGAAATGTATAATTATTTCTA
AGGTAAAATGAGTAGCAGGATTCTGAATAGGAGATTTTTTTTGGCCAGACCCATTTTGCAGCCAGTGGTTTGTATTTAGGAGTGAGTTGA
ACAAAGAAGACTCTAATCTGTTTTTGTGTTGTGGATTTTTTATTCTATTGATAAATCAGTAGCTTCCAGCTTCTCTTGTATCCTCTACTA
GTCATCTTTTTTGTTTCTTCAGAAATAAACATCCAGGGTCACTTCCCTGCCCTTGCCATATACTTACTAGGATGATGTACAGGTAAAACT
TTTAAAGGAAAGTACGGACAGGCAATTCCTAAAGTAAAAGAGAGCACATTATCAAAACTGGCTGTACTTAACAAATACCAACAAAAAGTC
ATTACACTTCTGGCAACAAATAATGTTTGATTTAAAAAGACAAGAATTTCCCCTTTTGCTCTTATTTTTTAAATATGCTATGTCCTTAAG
TGAGAAATGCACTTCAAAAATTTTCTTATTCTGAAGTCTAGCCGGAAAGTTTGAACTTGTGTTGCCTTTGGCTAGACTAGGTGAAATTAA
GGGGCTTAAGAGGGCACTGTTGTGTGGCCCTGTGGTAGATAATAGCCCTCCAAGCATGAGGATGGGAGATCTACCATTCACCAGTATTTC
CAAAGTTATATTCTTAAAAAGGCTAGATTTCTAATTTCCGTAGAATCTAGGTATGTTCTTTTCAACTCAGCATCTGATAAGAAAGTTTGG
GCAAGTAGGTGCGAAAAATTTACTCTAGATACCATTTTCCAGGAAAAAATATAATTCAAGTCCAACGTATTACTAGCTGTCACCTTCCCC
AACAATCAAATAAGCATTGTTATTGTCAAACACATTTACTTGTATAGTTCAGTGTTATATGTAATGGACTTAGGTATAATTCCTGTGCTA
TTCCCTTTTGATGCCAAACACCCTTTTGTAAGCTGTTTTGTTTGAAATCCAAATTTATATGTCTTAAAGTAAATGGCAGCATTGGGCTTT
CTTAATGTAATGACTCTTCTGCCATCCTATTTCTAGAGTTAGGCAGAAAATTCTGTAAATCTATCTTATTTCCAGTCTGTTTGTGACTAT
GGTGGGCAATAAATCTGATTTCCCAGAAAAACACATCTGGACCCCTATAGGTAAGGTAAACAAGCCTCATCTTAAATTGTTTGTACTTCC
GACCTGACCTCAAAACACCATCATCATCTAGAGCAGCAACAAGTAAAGAACAATGCACTGGAAATCACATATATGGGTCTAGCACCAGCC
TTTACATTACACAACTTTGCTTTGGGCAAGTCATTTAAATTTCTGTGCTTCAGTTTACTAAATCTATGAAACTGACTAGGTAACAGCTGA
CATGCTTTTCCAGCACTCCGTCTTTTACCTGTCTGATGTCACAAATTGATCATTCCTTTCTGGCCTTGAGATGCGTATCAACCCAGATAG
TCATTAACCCAGATAGTTGGCATTCAGGATAAAATGTTTTTGCCTTTCCTGTCCTGCAAGCTCTTTAAAGTCCAAAATATGCCTTTATAT
CTTTATGTGTAATAGGTATGAAATCTATTTCTTGGTTGTTGAATAGGATAGGCTTATTAGACATTCTAAAGTCAACTTTTTTCTCATATT
TAAACATTTACCCGTAGAAATTCAGTTTTTTAAAGTTTTAAGTCAGTTGATTGTACCAAACATTACTATTAAAAAAAAATCAAAGTCAGA
GACCAGAGTTTCCCTGCATCAGCGTTCAGTCAGGAGACAGGAACTATACTAATTTGAACATGTAAAGTTAAATATAATCCTTAATAATAA
CAGGATTGGAATAAGGGATAAAAGAAAGAGAATTCCTTCTATATATATGTATACACACACATATATATATATACATGTGTATATATGTGT
GTGTATGTATATTATATAATATACATACACACACACAAAGAATGTCAGACAAGGAGCAGCCACCATTCTGCTTACTTTCACTGGATTAAG
AGTTTCATAAGGGCAAGGGTTTTGTTTGTCTTACACTCCACTGGGGATTAATCTCCAGTGTCTAGAACAGTGCCTAACACATAAATAAAG
CCTCAATTATTATTTGTGGAATGGAATGGAATTTGAGTGAAATGGAATGGGAATAGAATGGACTGGAATGGAAATAGAAGTGGGAAGGGG
AATGGAAGGGGATAGAAGAGGATTGAAGAGGACAGAAGGAGATGGGATAAGATGGGATGGGATAGGATCGAATCTCAGGTCCAGGAGTCA
GAATAACTGAATCCTATTCCAGTTCTGCCATCAACAAGTCCTGTGAAATTTGGAAAGTCACTTAACCCTCTGGCCTTGTAGAATATCTCA
GTGGGCATGTCTGATGTTTCTTCATGGTTAGATATAGGTTGCATGTTTTGGGCAAGAATATCACAGGAATGATGCTGTGTTCTCAGTGCA
CCCAGTCAGGTAATGCATGATTTCAATTTCTCTCATTACTGATGATGTTAACTTTAATCACTTAGTGAATGAGAACATGAGCATCATTTT
GAAAGCAAACTGCAAAGTTTTGATGTCAACATTTTAGCAATTACGTATAATTTCCCCCAAGGATACTGGCTTTGAGATAATGTAAATATA

>15913_15913_2_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000368491_HDAC2_chr6_114281182_ENST00000519065_length(amino acids)=585AA_BP=114
MPVSPRPTLRASFRRRRSRRTDVRSRASLAHPALSPAMWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNH
IRRHSIASDSGDTGIGTSCSDSVEGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPD
NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLY
IDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCG
ADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTN
QNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAK

--------------------------------------------------------------
>15913_15913_3_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000419517_HDAC2_chr6_114281182_ENST00000398283_length(transcript)=7137nt_BP=820nt
AGTATCGCAAAATAGGCCAAGTCGCTGCCCTCTACTCAACTCGCAGGGCGGGAGGATGGAGACAGAGGGATGCGGCGGGAGGGCGGGACA
GCCCAGTCGCCGCCAAGGAGGCGAAGCGGGGTCGGGGTAGCTCACCCGCCCCCCGCAGTCCCCGCCCCCCGCAGTCCCCGCCCCGCGCGG
CGCCGCGCACGCCTGAAGTCATTGCCCGAGGCCCCGCCCCCTCGCGGCCCCAGCCCCGGCTCTGGCTCTGCCGGCGGAGGGGGCGGAGAG
AACCCGCAGCTGCAACTTCGCCTGGAGCCTTTGAGCCTGGGCTCAGCCGGGGATCTAGCAGCCGTCACCGCCGAGTCGCCGCTTCCCCGG
CGCGGGCCTCAGCCCAGCCGGCTTGGCCATGGCAGGCGCCGGCAGTGCGGCGAATCTGGCCCCTGCGCTCCCCGCCCGTAGCTGAGCAGC
CGTTAACCAGCCATCCCGCCTTTCCTCCTGCCCGTGTCGCCGAGGCCCACGCTCCGCGCAAGTTTCCGCCGCCGAAGAAGCAGGAGGACG
GACGTGAGGAGTCGGGCGTCCCTGGCCCACCCGGCCCTCTCGCCCGCGATGTGGGGGCGCTTCCTGGCTCCGGAGGCCAGCGGCCGGGAT
AGCCCCGGCGGAGCCCGCAGCTTCCCTGCCGGCCCAGATTATTCATCAGCATGGCTACCTGCTAATGAATCATTGTGGCAGGCCACAACT
GTTCCATCTAACCATCGAAATAACCATATCAGGAGACACAGTATAGCTTCTGACAGTGGAGACACTGGCATTGGAACTTCCTGTTCTGAT
AGCGTGGAAGGTGATATTGGAAATTATTATTATGGACAGGGTCATCCCATGAAGCCTCATAGAATCCGCATGACCCATAACTTGCTGTTA
AATTATGGCTTATACAGAAAAATGGAAATATATAGGCCCCATAAAGCCACTGCCGAAGAAATGACAAAATATCACAGTGATGAGTATATC
AAATTTCTACGGTCAATAAGACCAGATAACATGTCTGAGTATAGTAAGCAGATGCAGAGATTTAATGTTGGAGAAGATTGTCCAGTGTTT
GATGGACTCTTTGAGTTTTGTCAGCTCTCAACTGGCGGTTCAGTTGCTGGAGCTGTGAAGTTAAACCGACAACAGACTGATATGGCTGTT
AATTGGGCTGGAGGATTACATCATGCTAAGAAATCAGAAGCATCAGGATTCTGTTACGTTAATGATATTGTGCTTGCCATCCTTGAATTA
CTAAAGTATCATCAGAGAGTCTTATATATTGATATAGATATTCATCATGGTGATGGTGTTGAAGAAGCTTTTTATACAACAGATCGTGTA
ATGACGGTATCATTCCATAAATATGGGGAATACTTTCCTGGCACAGGAGACTTGAGGGATATTGGTGCTGGAAAAGGCAAATACTATGCT
GTCAATTTTCCAATGAGAGATGGTATAGATGATGAGTCATATGGGCAGATATTTAAGCCTATTATCTCAAAGGTGATGGAGATGTATCAA
CCTAGTGCTGTGGTATTACAGTGTGGTGCAGACTCATTATCTGGTGATAGACTGGGTTGTTTCAATCTAACAGTCAAAGGTCATGCTAAA
TGTGTAGAAGTTGTAAAAACTTTTAACTTACCATTACTGATGCTTGGAGGAGGTGGCTACACAATCCGTAATGTTGCTCGATGTTGGACA
TATGAGACTGCAGTTGCCCTTGATTGTGAGATTCCCAATGAGTTGCCATATAATGATTACTTTGAGTATTTTGGACCAGACTTCAAACTG
CATATTAGTCCTTCAAACATGACAAACCAGAACACTCCAGAATATATGGAAAAGATAAAACAGCGTTTGTTTGAAAATTTGCGCATGTTA
CCTCATGCACCTGGTGTCCAGATGCAAGCTATTCCAGAAGATGCTGTTCATGAAGACAGTGGAGATGAAGATGGAGAAGATCCAGACAAG
AGAATTTCTATTCGAGCATCAGACAAGCGGATAGCTTGTGATGAAGAATTCTCAGATTCTGAGGATGAAGGAGAAGGAGGTCGAAGAAAT
GTGGCTGATCATAAGAAAGGAGCAAAGAAAGCTAGAATTGAAGAAGATAAGAAAGAAACAGAGGACAAAAAAACAGACGTTAAGGAAGAA
GATAAATCCAAGGACAACAGTGGTGAAAAAACAGATACCAAAGGAACCAAATCAGAACAGCTCAGCAACCCCTGAATTTGACAGTCTCAC
CAATTTCAGAAAATCATTAAAAAGAAAATATTGAAAGGAAAATGTTTTCTTTTTGAAGACTTCTGGCTTCATTTTATACTACTTTGGCAT
GGACTGTATTTATTTTCAAATGGCTTTTTCGTTTTTGTTTTTCTTGGCAAGTTTTATTGTGAGTTTTTCTAATTATGAAGCAAAATTTCT
TTTCTCCACCATGCTTTATGTGATAGTATTTAAAATTGATGTGAGTTATTATGTCAAAAAAACTGATCTATTAAAGAAGTAATTGGCCTT
TCTGAGCTGATTTTTCCATCTTTTGTAATTATCTTTATTAAAAAATTGTACTTGGATTATCTTTTGTCTGTTTATTACTACAATATGAAG
TCTTGTTTCAGTGGCTAATGACATCATTTCTGTAGACTTACAATACACTCTAGGTGAAAGATAATGATTACAGCTTGAAAGATAACTATT
TGCTGTTTCTTTGGGAAGAGTATTTATAGTAATTATTACTTATCTTTGCAATAGAAATTCTACCACCTTGCCCTCTATAGCTTAGCCAGT
TAGTATCAGTGAAGATTAACATCCCATTACAATTTATGAAATAATACAGACTCTGCAATTGAGATGTAGGAGTTCTTTGAGTTGACCCAA
AGATTCTCAAAATTGAAATGGAAATTCTGAATTGAAAGAAGAAACTGACCAGAACTTGTATTGACCAGACTTGCCTATAGTATATTGCTG
GTTTAAAATGGAACCTGCAGACAAAACCTGTTTCTTTTACTGCATTTACATGGCATCCAGGTTCCATTATTATTTACGTGACATCCAGGT
TTCTAACTCAAGGAAATAAACACAACTGATTTATCATTCAGCAACTACTTATTGTGTGTCTGCCCATTTTAAGACTGTAGGAGTGTAACT
GAATATAATGGAAAAATGCTTTCACTCAGAGCTTACACTCAGAGCTTACATTCTAGTAGCAGGAAGCAGACAAATGGGGGTAACTCCTGC
TACTAAGATGTGCAAAGAAGACAAAACATTTTAGGAACTTGCCAAAATCAGTGAAATCTCCCTTTTTGTCAGGCCCACATTGATTCTTTT
GAGATTAAAAATTACAGAATGCCAGAAGATAATTCAGTCAAAAGTATTTCTCTTCAGTGCAGTAAAATATTAAAAGAAAAAATATTTCTC
TACAAGCCTCTTAAATGTTTCAGACATTCACAATAGCACCTAGACTTTTGTAATGAACAGCTGTGCACCCACCCCGACTTAACAAATATT
TTACTTTTGCTATATTTGCTTCGGTGTTTTTTTCTTAAAATACACCGAAATTGAAGCTCTCTTTGTGTACTTTGTCGTTTGTAATCCTCC
CTCCCTCCCAGCCTTAAGAAGTAATCACCATTGTGATTATTTTATCCATGTTTTTGTGAATATTTTACCCATGTTTTTGTACTTTTGCTA
CATATTTGTTATCAATCTGTAAACCTTTATGACATTAGGAACTAAGAAACTTAGTCCCTTCGTTAGGGGGATAATGAAATGTATTTAGTG
TTTGTGAAACATAGATGGTATGTATTTGGACAATTCTGTAACTTTGCTTTTTTTATTTTTATTTTTCCATAGCTTATTGGGGAACAGGTG
GTGTTTGGTTACATGATTAAGTTCTTTAGTGGTGATTTGTGGGATTTTGGTGGACCCATCACCCAAGCAGTGTACACTGCACCCTATTTG
TAATCTTTTATCCCTCGCCCCCCTCCCACCATGCCTCCCGTCTACCATGATGATCCTGTTTTAAATAAGAAAATACCATTTCGCAGGCTC
CAGATGTTCTGGCATCCTCCCTGTGGATTTCCCAGTGCCTGCAGCTCACAGGACAACAGGGGCTGTGGTAGAGTCACCTATGAGATCCTG
GAGTAGTGGATGGAGGAGATGGAACAGTGAAGACGGAAACTGAGCTCAGTATCCGGGTGCCAGGAGACAAAGGCCCTTTGCTTTTTTTCA
TTTAATATTCTGATCTACCCCTGTTGACACATGTTAAGTATAGTTCATTTTGACTGCTATGTATTATGTTCCATTGTGTGAACATACTGA
AATTGTACACTTCAATACTATACTGGATCTCCTTGGGTGTATTTAAGAGGTTTTGTTTTTCTAAGTAGTTGGTTATATACAACTAAAACC
TCAAGAGAACTATCTAAAGCAATTTCAGCAAGGTGATTTGGTACAGCATTAATAAACAGAAATCAGTAACACTTAGTGACCAAGTCTGTT
GGAAGAACAAAGACCCCCATTTGTAATAACAAAATTTTTAGAAATAATATGTAAAGAAGCTATGGTTCTTGTGTCTAGTAAGGTCAATGT
AACATAGTAAGATGTCAGAATACCCTAATACTTTAAAAAATTCATATAGGATAAAAATGATATTTGAAATTGGCAAGGAAAGACATTATT
TTGTAAGTGGAATTGGGACAACAACTGGTAACCAAATGGAAAACCCAGTTTTCTGCCCTCCACTAGAAGATTTAAATAGGAAAAGATAAA
ACTACCAAAAACCTAAACTCTTAAAGCAAATGGATTGAAGAAGGCCTAAGTGTGACACCAAACTCAACTATAAAAGATATATTTGATAAC
AAAAAAAAAATTAGTTCAGTGGACCAACAAAAACTTAGAAGACAAGTCAAGAAAAATGACAAAAGACAGAGTGGGAGGCAGATTTGTAAC
TCATCCAGGTCAAAAGGCTCATATCTAAAGATAGTAGAGGAACAAAATGTATAAGGATGTGAACTGGGAAACAAATACATATAAATAGTT
TGTAAATATGAAAAGATCTTTAACCTCAGTAAATAAAAAGCTATAGAGAGACTTATTTTTTAACTTAGTTTTTTAAACCTATTATGTTTA
TTTATTTTTTCTTTTTTTGAGACGGAGTCTCGCTGTTGCCCAGGCTGGTGTGCAATGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCC
CAGGTTGAAGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCTGTCACCACGCCCAGCTAATTGTTCGCATTTTTA
GTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCTCATGATCCACCCACCTTGGCCTTCCAAAGTGCTGGGAT
TACAGGTGTGAGCTGCCGCACCTGGCTGTTTATCTCTTTTTTTTAGAGAAAGGATCTCGGTCACCCAGGATGGAGTGTGGTAGCCTGATC
ATATCTCACTACATCTTAGAACTTCTAGGCTTAGGGTATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAAGTGTGCACCATCAC
ACCTAGCTGATTTTTACATTTTTATTTTGGAGAGATGGTGTCTCCCTGTGTTGCCCAGGCTGGTCACAAACTCCTAGGCTCAAGCGATTC
TCCTGACTCAGGCATGAGCCACCGTACCCGGCCTAAACCTATCATGTTACAGACTTAGAAAGCAACTATTGTCAAGTGTTTGAGGAAACT
CAGGTCAGGTTTGGTAAACTAAGATATTAACTCAAGTAAAGCTCTTTAATTCATTTAATGAAGGTGCCACATTGTCTCAGTTCTCTATGG
CATGGGTGAATGCTGTTCTAAGTCAGCATTGGTACTCTAAGCTAGTTACATCATATCTAAGCTTTGCCCTTCTACCAGAGCTGCTAGCAT
TCTGTCAATGGGCAATTATTTGAAGTTCTTACATTGAAGTTAGTCACCTACATCTTCTGTTTTTTATGGTTTTGATGTAGTAATACTGCT
GAAGTTTTTTTGATAACTGCGATTCATAATATTTGTTATTCATATTGTGATATAAATGATAAGGGCTTTTGAAAACAAGTAGTAATCATT
TCAATAGCTTAGGATCTCCACCATAATCTTAGGAAAATTACTAACCTCTGTGCCTCAGTTGCTTCATCATTTAAAATGAGGAAAATAATA
GTCCCTACTTAATAGGTTTGTTGTGAGGATTGAGTTAATAACATAGTTAATGCTCAGTAAGGGTTAGCTGCTATTTTTTTTTCTTTTTTT
TTTGAAAGAGTCTCACTCTGTTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCTCACTGCATCCTCTGCTTCCTAGGTTCAGGTGATT
CTCATGCTTCAGCCTCCCAAGCAGCTGGGAGTACAGGTGTGCACCACCACACCTGGCTAATTTTTGTATATTTAGTAGAGACGGGTTCTC
ACCATATTGTCCAGGCTGGTCTTGAACTCCTTACCTCAAATGATCCACCCGCCTGGGCCTCCCAAAGTGCTGGGATTACAAGCATGAGCC
ACCGCGCCTGGCTTGCTATTGTTATGAGGTAAAGGTAGATAGATGGGTGAGAGTGGTGCCAGGGGAAGTGTTAAATTTTTGAGTGTTCCT
TTAGATGCCAGATGGGTTGTATCTGAGCCTTTTATTGCAGTTTGATGCCTACTAGTGTGAAGACTACTAGGTCATAGTGGATAGAGAAGC
AATCTTTTGGAGACCTGATTTTAGCAAGGATACGAATAATATTTGACAACTTTGGGGGGATCTTGATGCCTCTGTAATTTACTCAAGGAT
AATCTCAAGAAAAATGGCATTAAGTAGATTACAGAAAAAATAGAACTATCATATTGTTATTATTGGCTATTTACATGAGCAATGCGGAGA
AATGTTTAGGATTACAGCATTTAGAAGCTTCTCAATTGCTGCATTTCCTCACTGTACCACAAGATGGCAGATACTGCATTTAAAATTTTT
TTTTCTGTGTGTTTTCTCTTATAGTCACTTGGTGGCCATGTAACAAGCAGAGCAACATGTATTAACAGATTCTTTTTGAATGCAATATTG

>15913_15913_3_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000419517_HDAC2_chr6_114281182_ENST00000398283_length(amino acids)=585AA_BP=114
MPVSPRPTLRASFRRRRSRRTDVRSRASLAHPALSPAMWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNH
IRRHSIASDSGDTGIGTSCSDSVEGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPD
NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLY
IDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCG
ADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTN
QNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAK

--------------------------------------------------------------
>15913_15913_4_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000419517_HDAC2_chr6_114281182_ENST00000519065_length(transcript)=10265nt_BP=820nt
AGTATCGCAAAATAGGCCAAGTCGCTGCCCTCTACTCAACTCGCAGGGCGGGAGGATGGAGACAGAGGGATGCGGCGGGAGGGCGGGACA
GCCCAGTCGCCGCCAAGGAGGCGAAGCGGGGTCGGGGTAGCTCACCCGCCCCCCGCAGTCCCCGCCCCCCGCAGTCCCCGCCCCGCGCGG
CGCCGCGCACGCCTGAAGTCATTGCCCGAGGCCCCGCCCCCTCGCGGCCCCAGCCCCGGCTCTGGCTCTGCCGGCGGAGGGGGCGGAGAG
AACCCGCAGCTGCAACTTCGCCTGGAGCCTTTGAGCCTGGGCTCAGCCGGGGATCTAGCAGCCGTCACCGCCGAGTCGCCGCTTCCCCGG
CGCGGGCCTCAGCCCAGCCGGCTTGGCCATGGCAGGCGCCGGCAGTGCGGCGAATCTGGCCCCTGCGCTCCCCGCCCGTAGCTGAGCAGC
CGTTAACCAGCCATCCCGCCTTTCCTCCTGCCCGTGTCGCCGAGGCCCACGCTCCGCGCAAGTTTCCGCCGCCGAAGAAGCAGGAGGACG
GACGTGAGGAGTCGGGCGTCCCTGGCCCACCCGGCCCTCTCGCCCGCGATGTGGGGGCGCTTCCTGGCTCCGGAGGCCAGCGGCCGGGAT
AGCCCCGGCGGAGCCCGCAGCTTCCCTGCCGGCCCAGATTATTCATCAGCATGGCTACCTGCTAATGAATCATTGTGGCAGGCCACAACT
GTTCCATCTAACCATCGAAATAACCATATCAGGAGACACAGTATAGCTTCTGACAGTGGAGACACTGGCATTGGAACTTCCTGTTCTGAT
AGCGTGGAAGGTGATATTGGAAATTATTATTATGGACAGGGTCATCCCATGAAGCCTCATAGAATCCGCATGACCCATAACTTGCTGTTA
AATTATGGCTTATACAGAAAAATGGAAATATATAGGCCCCATAAAGCCACTGCCGAAGAAATGACAAAATATCACAGTGATGAGTATATC
AAATTTCTACGGTCAATAAGACCAGATAACATGTCTGAGTATAGTAAGCAGATGCAGAGATTTAATGTTGGAGAAGATTGTCCAGTGTTT
GATGGACTCTTTGAGTTTTGTCAGCTCTCAACTGGCGGTTCAGTTGCTGGAGCTGTGAAGTTAAACCGACAACAGACTGATATGGCTGTT
AATTGGGCTGGAGGATTACATCATGCTAAGAAATCAGAAGCATCAGGATTCTGTTACGTTAATGATATTGTGCTTGCCATCCTTGAATTA
CTAAAGTATCATCAGAGAGTCTTATATATTGATATAGATATTCATCATGGTGATGGTGTTGAAGAAGCTTTTTATACAACAGATCGTGTA
ATGACGGTATCATTCCATAAATATGGGGAATACTTTCCTGGCACAGGAGACTTGAGGGATATTGGTGCTGGAAAAGGCAAATACTATGCT
GTCAATTTTCCAATGAGAGATGGTATAGATGATGAGTCATATGGGCAGATATTTAAGCCTATTATCTCAAAGGTGATGGAGATGTATCAA
CCTAGTGCTGTGGTATTACAGTGTGGTGCAGACTCATTATCTGGTGATAGACTGGGTTGTTTCAATCTAACAGTCAAAGGTCATGCTAAA
TGTGTAGAAGTTGTAAAAACTTTTAACTTACCATTACTGATGCTTGGAGGAGGTGGCTACACAATCCGTAATGTTGCTCGATGTTGGACA
TATGAGACTGCAGTTGCCCTTGATTGTGAGATTCCCAATGAGTTGCCATATAATGATTACTTTGAGTATTTTGGACCAGACTTCAAACTG
CATATTAGTCCTTCAAACATGACAAACCAGAACACTCCAGAATATATGGAAAAGATAAAACAGCGTTTGTTTGAAAATTTGCGCATGTTA
CCTCATGCACCTGGTGTCCAGATGCAAGCTATTCCAGAAGATGCTGTTCATGAAGACAGTGGAGATGAAGATGGAGAAGATCCAGACAAG
AGAATTTCTATTCGAGCATCAGACAAGCGGATAGCTTGTGATGAAGAATTCTCAGATTCTGAGGATGAAGGAGAAGGAGGTCGAAGAAAT
GTGGCTGATCATAAGAAAGGAGCAAAGAAAGCTAGAATTGAAGAAGATAAGAAAGAAACAGAGGACAAAAAAACAGACGTTAAGGAAGAA
GATAAATCCAAGGACAACAGTGGTGAAAAAACAGATACCAAAGGAACCAAATCAGAACAGCTCAGCAACCCCTGAATTTGACAGTCTCAC
CAATTTCAGAAAATCATTAAAAAGAAAATATTGAAAGGAAAATGTTTTCTTTTTGAAGACTTCTGGCTTCATTTTATACTACTTTGGCAT
GGACTGTATTTATTTTCAAATGGCTTTTTCGTTTTTGTTTTTCTTGGCAAGTTTTATTGTGAGTTTTTCTAATTATGAAGCAAAATTTCT
TTTCTCCACCATGCTTTATGTGATAGTATTTAAAATTGATGTGAGTTATTATGTCAAAAAAACTGATCTATTAAAGAAGTAATTGGCCTT
TCTGAGCTGATTTTTCCATCTTTTGTAATTATCTTTATTAAAAAATTGTACTTGGATTATCTTTTGTCTGTTTATTACTACAATATGAAG
TCTTGTTTCAGTGGCTAATGACATCATTTCTGTAGACTTACAATACACTCTAGGTGAAAGATAATGATTACAGCTTGAAAGATAACTATT
TGCTGTTTCTTTGGGAAGAGTATTTATAGTAATTATTACTTATCTTTGCAATAGAAATTCTACCACCTTGCCCTCTATAGCTTAGCCAGT
TAGTATCAGTGAAGATTAACATCCCATTACAATTTATGAAATAATACAGACTCTGCAATTGAGATGTAGGAGTTCTTTGAGTTGACCCAA
AGATTCTCAAAATTGAAATGGAAATTCTGAATTGAAAGAAGAAACTGACCAGAACTTGTATTGACCAGACTTGCCTATAGTATATTGCTG
GTTTAAAATGGAACCTGCAGACAAAACCTGTTTCTTTTACTGCATTTACATGGCATCCAGGTTCCATTATTATTTACGTGACATCCAGGT
TTCTAACTCAAGGAAATAAACACAACTGATTTATCATTCAGCAACTACTTATTGTGTGTCTGCCCATTTTAAGACTGTAGGAGTGTAACT
GAATATAATGGAAAAATGCTTTCACTCAGAGCTTACACTCAGAGCTTACATTCTAGTAGCAGGAAGCAGACAAATGGGGGTAACTCCTGC
TACTAAGATGTGCAAAGAAGACAAAACATTTTAGGAACTTGCCAAAATCAGTGAAATCTCCCTTTTTGTCAGGCCCACATTGATTCTTTT
GAGATTAAAAATTACAGAATGCCAGAAGATAATTCAGTCAAAAGTATTTCTCTTCAGTGCAGTAAAATATTAAAAGAAAAAATATTTCTC
TACAAGCCTCTTAAATGTTTCAGACATTCACAATAGCACCTAGACTTTTGTAATGAACAGCTGTGCACCCACCCCGACTTAACAAATATT
TTACTTTTGCTATATTTGCTTCGGTGTTTTTTTCTTAAAATACACCGAAATTGAAGCTCTCTTTGTGTACTTTGTCGTTTGTAATCCTCC
CTCCCTCCCAGCCTTAAGAAGTAATCACCATTGTGATTATTTTATCCATGTTTTTGTGAATATTTTACCCATGTTTTTGTACTTTTGCTA
CATATTTGTTATCAATCTGTAAACCTTTATGACATTAGGAACTAAGAAACTTAGTCCCTTCGTTAGGGGGATAATGAAATGTATTTAGTG
TTTGTGAAACATAGATGGTATGTATTTGGACAATTCTGTAACTTTGCTTTTTTTATTTTTATTTTTCCATAGCTTATTGGGGAACAGGTG
GTGTTTGGTTACATGATTAAGTTCTTTAGTGGTGATTTGTGGGATTTTGGTGGACCCATCACCCAAGCAGTGTACACTGCACCCTATTTG
TAATCTTTTATCCCTCGCCCCCCTCCCACCATGCCTCCCGTCTACCATGATGATCCTGTTTTAAATAAGAAAATACCATTTCGCAGGCTC
CAGATGTTCTGGCATCCTCCCTGTGGATTTCCCAGTGCCTGCAGCTCACAGGACAACAGGGGCTGTGGTAGAGTCACCTATGAGATCCTG
GAGTAGTGGATGGAGGAGATGGAACAGTGAAGACGGAAACTGAGCTCAGTATCCGGGTGCCAGGAGACAAAGGCCCTTTGCTTTTTTTCA
TTTAATATTCTGATCTACCCCTGTTGACACATGTTAAGTATAGTTCATTTTGACTGCTATGTATTATGTTCCATTGTGTGAACATACTGA
AATTGTACACTTCAATACTATACTGGATCTCCTTGGGTGTATTTAAGAGGTTTTGTTTTTCTAAGTAGTTGGTTATATACAACTAAAACC
TCAAGAGAACTATCTAAAGCAATTTCAGCAAGGTGATTTGGTACAGCATTAATAAACAGAAATCAGTAACACTTAGTGACCAAGTCTGTT
GGAAGAACAAAGACCCCCATTTGTAATAACAAAATTTTTAGAAATAATATGTAAAGAAGCTATGGTTCTTGTGTCTAGTAAGGTCAATGT
AACATAGTAAGATGTCAGAATACCCTAATACTTTAAAAAATTCATATAGGATAAAAATGATATTTGAAATTGGCAAGGAAAGACATTATT
TTGTAAGTGGAATTGGGACAACAACTGGTAACCAAATGGAAAACCCAGTTTTCTGCCCTCCACTAGAAGATTTAAATAGGAAAAGATAAA
ACTACCAAAAACCTAAACTCTTAAAGCAAATGGATTGAAGAAGGCCTAAGTGTGACACCAAACTCAACTATAAAAGATATATTTGATAAC
AAAAAAAAAATTAGTTCAGTGGACCAACAAAAACTTAGAAGACAAGTCAAGAAAAATGACAAAAGACAGAGTGGGAGGCAGATTTGTAAC
TCATCCAGGTCAAAAGGCTCATATCTAAAGATAGTAGAGGAACAAAATGTATAAGGATGTGAACTGGGAAACAAATACATATAAATAGTT
TGTAAATATGAAAAGATCTTTAACCTCAGTAAATAAAAAGCTATAGAGAGACTTATTTTTTAACTTAGTTTTTTAAACCTATTATGTTTA
TTTATTTTTTCTTTTTTTGAGACGGAGTCTCGCTGTTGCCCAGGCTGGTGTGCAATGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCC
CAGGTTGAAGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCTGTCACCACGCCCAGCTAATTGTTCGCATTTTTA
GTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCTCATGATCCACCCACCTTGGCCTTCCAAAGTGCTGGGAT
TACAGGTGTGAGCTGCCGCACCTGGCTGTTTATCTCTTTTTTTTAGAGAAAGGATCTCGGTCACCCAGGATGGAGTGTGGTAGCCTGATC
ATATCTCACTACATCTTAGAACTTCTAGGCTTAGGGTATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAAGTGTGCACCATCAC
ACCTAGCTGATTTTTACATTTTTATTTTGGAGAGATGGTGTCTCCCTGTGTTGCCCAGGCTGGTCACAAACTCCTAGGCTCAAGCGATTC
TCCTGACTCAGGCATGAGCCACCGTACCCGGCCTAAACCTATCATGTTACAGACTTAGAAAGCAACTATTGTCAAGTGTTTGAGGAAACT
CAGGTCAGGTTTGGTAAACTAAGATATTAACTCAAGTAAAGCTCTTTAATTCATTTAATGAAGGTGCCACATTGTCTCAGTTCTCTATGG
CATGGGTGAATGCTGTTCTAAGTCAGCATTGGTACTCTAAGCTAGTTACATCATATCTAAGCTTTGCCCTTCTACCAGAGCTGCTAGCAT
TCTGTCAATGGGCAATTATTTGAAGTTCTTACATTGAAGTTAGTCACCTACATCTTCTGTTTTTTATGGTTTTGATGTAGTAATACTGCT
GAAGTTTTTTTGATAACTGCGATTCATAATATTTGTTATTCATATTGTGATATAAATGATAAGGGCTTTTGAAAACAAGTAGTAATCATT
TCAATAGCTTAGGATCTCCACCATAATCTTAGGAAAATTACTAACCTCTGTGCCTCAGTTGCTTCATCATTTAAAATGAGGAAAATAATA
GTCCCTACTTAATAGGTTTGTTGTGAGGATTGAGTTAATAACATAGTTAATGCTCAGTAAGGGTTAGCTGCTATTTTTTTTTCTTTTTTT
TTTGAAAGAGTCTCACTCTGTTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCTCACTGCATCCTCTGCTTCCTAGGTTCAGGTGATT
CTCATGCTTCAGCCTCCCAAGCAGCTGGGAGTACAGGTGTGCACCACCACACCTGGCTAATTTTTGTATATTTAGTAGAGACGGGTTCTC
ACCATATTGTCCAGGCTGGTCTTGAACTCCTTACCTCAAATGATCCACCCGCCTGGGCCTCCCAAAGTGCTGGGATTACAAGCATGAGCC
ACCGCGCCTGGCTTGCTATTGTTATGAGGTAAAGGTAGATAGATGGGTGAGAGTGGTGCCAGGGGAAGTGTTAAATTTTTGAGTGTTCCT
TTAGATGCCAGATGGGTTGTATCTGAGCCTTTTATTGCAGTTTGATGCCTACTAGTGTGAAGACTACTAGGTCATAGTGGATAGAGAAGC
AATCTTTTGGAGACCTGATTTTAGCAAGGATACGAATAATATTTGACAACTTTGGGGGGATCTTGATGCCTCTGTAATTTACTCAAGGAT
AATCTCAAGAAAAATGGCATTAAGTAGATTACAGAAAAAATAGAACTATCATATTGTTATTATTGGCTATTTACATGAGCAATGCGGAGA
AATGTTTAGGATTACAGCATTTAGAAGCTTCTCAATTGCTGCATTTCCTCACTGTACCACAAGATGGCAGATACTGCATTTAAAATTTTT
TTTTCTGTGTGTTTTCTCTTATAGTCACTTGGTGGCCATGTAACAAGCAGAGCAACATGTATTAACAGATTCTTTTTGAATGCAATATTG
GATTAAAAACTTTGAATTAAACTACAATTAAGTTTACTGATTTAGGTTTTCCTATAAGAATTATAACACTAATTTCTAAGTTTTACATCT
GCAAAACACAGTAGAGTGTATCTGGTAGTCATTGACTAATTGTGACTTTGCTAGTCAGACAAAATGGAACTGAATATTAGAGCCAGAATA
ATTTTCTGTTTTGACTGGTGGTAAGAATCAGTTAGTATACAGAATGGGAAAGAATTGAAATTTATTTCTAGGAATTATAGTTATAGTGAA
GTTAATATTCAGGGGCATTGGGTGCTTGTTCCACGACTTTTGTTTACTGAACTAAGTACCTAACCCCTTTGGTCTTTGAACACTGCAGAG
TTATGATTAGGATTATTAATGAAAAATTCTTTTTTAGTAGAACAAACAGTTAAGGACAGAAGACACCTTGATTAGATTCTGTTATTTGCT
CTTTTTATTAAGATTGTTTTTACTCTAAATGTTAAAGAAATGTATAATTATTTCTAAGGTAAAATGAGTAGCAGGATTCTGAATAGGAGA
TTTTTTTTGGCCAGACCCATTTTGCAGCCAGTGGTTTGTATTTAGGAGTGAGTTGAACAAAGAAGACTCTAATCTGTTTTTGTGTTGTGG
ATTTTTTATTCTATTGATAAATCAGTAGCTTCCAGCTTCTCTTGTATCCTCTACTAGTCATCTTTTTTGTTTCTTCAGAAATAAACATCC
AGGGTCACTTCCCTGCCCTTGCCATATACTTACTAGGATGATGTACAGGTAAAACTTTTAAAGGAAAGTACGGACAGGCAATTCCTAAAG
TAAAAGAGAGCACATTATCAAAACTGGCTGTACTTAACAAATACCAACAAAAAGTCATTACACTTCTGGCAACAAATAATGTTTGATTTA
AAAAGACAAGAATTTCCCCTTTTGCTCTTATTTTTTAAATATGCTATGTCCTTAAGTGAGAAATGCACTTCAAAAATTTTCTTATTCTGA
AGTCTAGCCGGAAAGTTTGAACTTGTGTTGCCTTTGGCTAGACTAGGTGAAATTAAGGGGCTTAAGAGGGCACTGTTGTGTGGCCCTGTG
GTAGATAATAGCCCTCCAAGCATGAGGATGGGAGATCTACCATTCACCAGTATTTCCAAAGTTATATTCTTAAAAAGGCTAGATTTCTAA
TTTCCGTAGAATCTAGGTATGTTCTTTTCAACTCAGCATCTGATAAGAAAGTTTGGGCAAGTAGGTGCGAAAAATTTACTCTAGATACCA
TTTTCCAGGAAAAAATATAATTCAAGTCCAACGTATTACTAGCTGTCACCTTCCCCAACAATCAAATAAGCATTGTTATTGTCAAACACA
TTTACTTGTATAGTTCAGTGTTATATGTAATGGACTTAGGTATAATTCCTGTGCTATTCCCTTTTGATGCCAAACACCCTTTTGTAAGCT
GTTTTGTTTGAAATCCAAATTTATATGTCTTAAAGTAAATGGCAGCATTGGGCTTTCTTAATGTAATGACTCTTCTGCCATCCTATTTCT
AGAGTTAGGCAGAAAATTCTGTAAATCTATCTTATTTCCAGTCTGTTTGTGACTATGGTGGGCAATAAATCTGATTTCCCAGAAAAACAC
ATCTGGACCCCTATAGGTAAGGTAAACAAGCCTCATCTTAAATTGTTTGTACTTCCGACCTGACCTCAAAACACCATCATCATCTAGAGC
AGCAACAAGTAAAGAACAATGCACTGGAAATCACATATATGGGTCTAGCACCAGCCTTTACATTACACAACTTTGCTTTGGGCAAGTCAT
TTAAATTTCTGTGCTTCAGTTTACTAAATCTATGAAACTGACTAGGTAACAGCTGACATGCTTTTCCAGCACTCCGTCTTTTACCTGTCT
GATGTCACAAATTGATCATTCCTTTCTGGCCTTGAGATGCGTATCAACCCAGATAGTCATTAACCCAGATAGTTGGCATTCAGGATAAAA
TGTTTTTGCCTTTCCTGTCCTGCAAGCTCTTTAAAGTCCAAAATATGCCTTTATATCTTTATGTGTAATAGGTATGAAATCTATTTCTTG
GTTGTTGAATAGGATAGGCTTATTAGACATTCTAAAGTCAACTTTTTTCTCATATTTAAACATTTACCCGTAGAAATTCAGTTTTTTAAA
GTTTTAAGTCAGTTGATTGTACCAAACATTACTATTAAAAAAAAATCAAAGTCAGAGACCAGAGTTTCCCTGCATCAGCGTTCAGTCAGG
AGACAGGAACTATACTAATTTGAACATGTAAAGTTAAATATAATCCTTAATAATAACAGGATTGGAATAAGGGATAAAAGAAAGAGAATT
CCTTCTATATATATGTATACACACACATATATATATATACATGTGTATATATGTGTGTGTATGTATATTATATAATATACATACACACAC
ACAAAGAATGTCAGACAAGGAGCAGCCACCATTCTGCTTACTTTCACTGGATTAAGAGTTTCATAAGGGCAAGGGTTTTGTTTGTCTTAC
ACTCCACTGGGGATTAATCTCCAGTGTCTAGAACAGTGCCTAACACATAAATAAAGCCTCAATTATTATTTGTGGAATGGAATGGAATTT
GAGTGAAATGGAATGGGAATAGAATGGACTGGAATGGAAATAGAAGTGGGAAGGGGAATGGAAGGGGATAGAAGAGGATTGAAGAGGACA
GAAGGAGATGGGATAAGATGGGATGGGATAGGATCGAATCTCAGGTCCAGGAGTCAGAATAACTGAATCCTATTCCAGTTCTGCCATCAA
CAAGTCCTGTGAAATTTGGAAAGTCACTTAACCCTCTGGCCTTGTAGAATATCTCAGTGGGCATGTCTGATGTTTCTTCATGGTTAGATA
TAGGTTGCATGTTTTGGGCAAGAATATCACAGGAATGATGCTGTGTTCTCAGTGCACCCAGTCAGGTAATGCATGATTTCAATTTCTCTC
ATTACTGATGATGTTAACTTTAATCACTTAGTGAATGAGAACATGAGCATCATTTTGAAAGCAAACTGCAAAGTTTTGATGTCAACATTT
TAGCAATTACGTATAATTTCCCCCAAGGATACTGGCTTTGAGATAATGTAAATATACATGGGAAAGACAAAGCTCAAATAAAGGAAAAAG

>15913_15913_4_CEP85L-HDAC2_CEP85L_chr6_118953616_ENST00000419517_HDAC2_chr6_114281182_ENST00000519065_length(amino acids)=585AA_BP=114
MPVSPRPTLRASFRRRRSRRTDVRSRASLAHPALSPAMWGRFLAPEASGRDSPGGARSFPAGPDYSSAWLPANESLWQATTVPSNHRNNH
IRRHSIASDSGDTGIGTSCSDSVEGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPD
NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLY
IDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCG
ADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTN
QNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CEP85L-HDAC2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CEP85L-HDAC2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CEP85L-HDAC2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source