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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CERK-SCUBE1 (FusionGDB2 ID:15964)

Fusion Gene Summary for CERK-SCUBE1

check button Fusion gene summary
Fusion gene informationFusion gene name: CERK-SCUBE1
Fusion gene ID: 15964
HgeneTgene
Gene symbol

CERK

SCUBE1

Gene ID

64781

80274

Gene nameceramide kinasesignal peptide, CUB domain and EGF like domain containing 1
SynonymsLK4|dA59H18.2|dA59H18.3|hCERK-
Cytomap

22q13.31

22q13.2

Type of geneprotein-codingprotein-coding
Descriptionceramide kinaseacylsphingosine kinaselipid kinase 4lipid kinase LK4signal peptide, CUB and EGF-like domain-containing protein 1signal peptide, CUB domain, EGF-like 1signal peptide-CUB domain-EGF-related 1
Modification date2020031320200313
UniProtAcc

Q8TCT0

.
Ensembl transtripts involved in fusion geneENST00000216264, ENST00000541677, 
ENST00000471929, 		ENST00000470433, 
ENST00000290460, ENST00000360835, 
Fusion gene scores* DoF score18 X 11 X 7=13869 X 7 X 9=567
# samples 189
** MAII scorelog2(18/1386*10)=-2.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/567*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CERK [Title/Abstract] AND SCUBE1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCERK(47103740)-SCUBE1(43654341), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCERK

GO:0006672

ceramide metabolic process

19501188


check buttonFusion gene breakpoints across CERK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SCUBE1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-A8D0-01ACERKchr22

47103740

-SCUBE1chr22

43654341

-


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Fusion Gene ORF analysis for CERK-SCUBE1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000216264ENST00000470433CERKchr22

47103740

-SCUBE1chr22

43654341

-
5CDS-intronENST00000541677ENST00000470433CERKchr22

47103740

-SCUBE1chr22

43654341

-
In-frameENST00000216264ENST00000290460CERKchr22

47103740

-SCUBE1chr22

43654341

-
In-frameENST00000216264ENST00000360835CERKchr22

47103740

-SCUBE1chr22

43654341

-
In-frameENST00000541677ENST00000290460CERKchr22

47103740

-SCUBE1chr22

43654341

-
In-frameENST00000541677ENST00000360835CERKchr22

47103740

-SCUBE1chr22

43654341

-
intron-3CDSENST00000471929ENST00000290460CERKchr22

47103740

-SCUBE1chr22

43654341

-
intron-3CDSENST00000471929ENST00000360835CERKchr22

47103740

-SCUBE1chr22

43654341

-
intron-intronENST00000471929ENST00000470433CERKchr22

47103740

-SCUBE1chr22

43654341

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000216264CERKchr2247103740-ENST00000360835SCUBE1chr2243654341-989982811331841023
ENST00000216264CERKchr2247103740-ENST00000290460SCUBE1chr2243654341-24148281131261382
ENST00000541677CERKchr2247103740-ENST00000360835SCUBE1chr2243654341-97817105893066825
ENST00000541677CERKchr2247103740-ENST00000290460SCUBE1chr2243654341-229671059616185

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000216264ENST00000360835CERKchr2247103740-SCUBE1chr2243654341-0.0017819290.998218
ENST00000216264ENST00000290460CERKchr2247103740-SCUBE1chr2243654341-0.0224479880.97755194
ENST00000541677ENST00000360835CERKchr2247103740-SCUBE1chr2243654341-0.0030262550.99697375
ENST00000541677ENST00000290460CERKchr2247103740-SCUBE1chr2243654341-0.37035230.6296477

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Fusion Genomic Features for CERK-SCUBE1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CERK-SCUBE1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:47103740/chr22:43654341)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CERK

Q8TCT0

.
FUNCTION: Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed:11956206, PubMed:16269826, PubMed:19168031). Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines (PubMed:11956206, PubMed:16269826, PubMed:19168031). Shows a greater preference for D-erythro isomer of ceramides (PubMed:16269826). Binds phosphoinositides (PubMed:19168031). {ECO:0000269|PubMed:11956206, ECO:0000269|PubMed:16269826, ECO:0000269|PubMed:19168031}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613138_140238538.0Nucleotide bindingATP
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613170_174238538.0Nucleotide bindingATP
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613239_241238538.0Nucleotide bindingATP
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613195_198238538.0RegionSubstrate binding
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-6131_115238538.0RegionEssential for enzyme activity
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-6131_125238538.0RegionRequired for binding to sulfatide and phosphoinositides
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422206_241203989.0DomainEGF-like 5
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422245_280203989.0DomainEGF-like 6
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422282_322203989.0DomainEGF-like 7%3B calcium-binding
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422323_361203989.0DomainEGF-like 8%3B calcium-binding
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422362_402203989.0DomainEGF-like 9%3B calcium-binding
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422798_910203989.0DomainCUB

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613128_278238538.0DomainDAGKc
HgeneCERKchr22:47103740chr22:43654341ENST00000216264-613502_504238538.0Nucleotide bindingATP
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422117_153203989.0DomainEGF-like 3%3B calcium-binding
TgeneSCUBE1chr22:47103740chr22:43654341ENST00000360835422166_202203989.0DomainEGF-like 4
TgeneSCUBE1chr22:47103740chr22:43654341ENST0000036083542233_73203989.0DomainEGF-like 1%3B calcium-binding
TgeneSCUBE1chr22:47103740chr22:43654341ENST0000036083542274_116203989.0DomainEGF-like 2%3B calcium-binding


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Fusion Gene Sequence for CERK-SCUBE1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>15964_15964_1_CERK-SCUBE1_CERK_chr22_47103740_ENST00000216264_SCUBE1_chr22_43654341_ENST00000290460_length(transcript)=2414nt_BP=828nt
CCGCCTCCCGCCGCCCGCCGCCCGCCGCCCGGGCCACTGCAGGGGCCGCTAACGGTCCGGCGCCCCTCGGCGTCCGCGCGCCCCCAGCCT
GGCGGACGAGCCCGGCGGCGGAGATGGGGGCGACGGGGGCGGCGGAGCCGCTGCAATCCGTGCTGTGGGTGAAGCAGCAGCGCTGCGCCG
TGAGCCTGGAGCCCGCGCGGGCTCTGCTGCGCTGGTGGCGGAGCCCGGGGCCCGGAGCCGGCGCCCCCGGCGCGGATGCCTGCTCTGTGC
CTGTATCTGAGATCATCGCCGTTGAGGAAACAGACGTTCACGGGAAACATCAAGGCAGTGGAAAATGGCAGAAAATGGAAAAGCCTTACG
CTTTTACAGTTCACTGTGTAAAGAGAGCACGACGGCACCGCTGGAAGTGGGCGCAGGTGACTTTCTGGTGTCCAGAGGAGCAGCTGTGTC
ACTTGTGGCTGCAGACCCTGCGGGAGATGCTGGAGAAGCTGACGTCCAGACCAAAGCATTTACTGGTATTTATCAACCCGTTTGGAGGAA
AAGGACAAGGCAAGCGGATATATGAAAGAAAAGTGGCACCACTGTTCACCTTAGCCTCCATCACCACTGACATCATCGTTACTGAACATG
CTAATCAGGCCAAGGAGACTCTGTATGAGATTAACATAGACAAATACGACGGCATCGTCTGTGTCGGCGGAGATGGTATGTTCAGCGAGG
TGCTGCACGGTCTGATTGGGAGGACGCAGAGGAGCGCCGGGGTCGACCAGAACCACCCCCGGGCTGTGCTGGTCCCCAGTAGCCTCCGGA
TTGGAATCATTCCCGCAGTAACCTGTAATTATGGAAACGGAGGCTGCCAGCACAGCTGTGAGGACACAGACACAGGCCCCACGTGTGGTT
GCCACCAGAAGTACGCCCTCCACTCAGACGGTCGCACGTGCATCGAGAAGGATGAGGCTGCAATTGAGCGCTCTCAGTTCAATGCCACGT
CAGTAGCTGATGTGGACAAGCGGGTGAAACGGCGGCTACTCATGGAGACGTGCGCAGTCAATAACGGAGGCTGCGACCGGACATGCAAGG
ACACAGCCACTGGCGTGCGATGCAGCTGCCCCGTTGGATTCACACTGCAGCCGGACGGGAAGACATGCAAAGGTCAGCATGTGGAGCTGT
GTGGGTGCCCCTGCCTGTACTGGCCTGGCCAAGAGCCTCCGTGTGCTTGCATAGCCGGGCCCAGGGCTGGGCTGAACGGGGGCCACGTGT
AGCTGTGGGAAAGGACACGTGGCAATCATTTGCTTTGCTGTTGGAGAGGCCAGGAAGAGGGAGGGCTGGCCAGCAGCAGGGTCCCCAGCA
GAGTTCGAGAGAACACAGGTCCCACGGCACATCAGCAGGTTCCTGGGCCAAAAAGGCACTGATGTCAGAGAATTTGGCTGCACGCTGGGT
TAAACAGTTAAGCCAGCGTCTCTACTGTGGGACTTCCTGGGCCCTCAGTGATAGTGTGGCTTCCCAAGGCGCGTAGAATGTAGCGCGTTT
CCGAACCCCTTGACCTTTGGTTGCAGTGGGTCTTGCAGAGCTGATGGGGACAGTCTGGTGTTGGGCCATCTGGGACACACAGGTCTACTC
ATGCCAGGAAAAATAAGGACAGTGTGTCACTACTAGGGGGGCGAGGCTAGGGGGATCCCATCTGAAAAGATAAGGACTCAGGACTTCTGC
TTGCCATCAGAAAATGAGGAGTCAGGAAGACCTGAGAGTGACTGGTTGAAGGAAGGAGGGACAGGGCTGGCCTGCTGGTGGCTGGCAGTG
AGGGAAGGCAGAGGTGTATCCTCCCACTTGTCCCCTGAGTCACCCCACAAAGACTTACTGAGTACCTCCTGGGTTGAGGGGACCCTCAGG
AAACAGGAAGCCCAGGGAGCTGGGAGAGGAGAGCTGGGTGGGCTCTCGAGACAGCCCTGCAGATGAGGAGGTCCAGCTACCCCCAAAGGA
CAGACGGAGCCCCAAGAAGCTGTGGGCCCTGGGGCAGGGTGTTAGGCCTGAGTGCCGGAGCCCTCTGTGCAGAAGGGTGAGGGGCAGTGC
TCAGTGCCCCCAGCATCACTCCAGACCACCCTCCAAACGCCCCCACCCCAGCGCTGGGCAGTACCCCCACACTCTGCCAGGAAGGGAGAG
CCTAGAGAGCAGGGCGTGGAGGGGAGAGGAACTGGAACTTCCAAAGTCCCATCGGGGAAAATATTGAAAGTGGAGGTTAGGGTGACTTAA
AATAGCTTGAGGTGGACTTTTTTTAAGCCTGTAAAAATAAATGTATTTTTGTACAGTGTATGACTTCTTCCTTGCCAACTTGCTGGGAAG

>15964_15964_1_CERK-SCUBE1_CERK_chr22_47103740_ENST00000216264_SCUBE1_chr22_43654341_ENST00000290460_length(amino acids)=382AA_BP=238
MGATGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEETDVHGKHQGSGKWQKMEKPYAFTVHCVK
RARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL
YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAVTCNYGNGGCQHSCEDTDTGPTCGCHQKYALH
SDGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKGQHVELCGCPCLYW

--------------------------------------------------------------
>15964_15964_2_CERK-SCUBE1_CERK_chr22_47103740_ENST00000216264_SCUBE1_chr22_43654341_ENST00000360835_length(transcript)=9899nt_BP=828nt
CCGCCTCCCGCCGCCCGCCGCCCGCCGCCCGGGCCACTGCAGGGGCCGCTAACGGTCCGGCGCCCCTCGGCGTCCGCGCGCCCCCAGCCT
GGCGGACGAGCCCGGCGGCGGAGATGGGGGCGACGGGGGCGGCGGAGCCGCTGCAATCCGTGCTGTGGGTGAAGCAGCAGCGCTGCGCCG
TGAGCCTGGAGCCCGCGCGGGCTCTGCTGCGCTGGTGGCGGAGCCCGGGGCCCGGAGCCGGCGCCCCCGGCGCGGATGCCTGCTCTGTGC
CTGTATCTGAGATCATCGCCGTTGAGGAAACAGACGTTCACGGGAAACATCAAGGCAGTGGAAAATGGCAGAAAATGGAAAAGCCTTACG
CTTTTACAGTTCACTGTGTAAAGAGAGCACGACGGCACCGCTGGAAGTGGGCGCAGGTGACTTTCTGGTGTCCAGAGGAGCAGCTGTGTC
ACTTGTGGCTGCAGACCCTGCGGGAGATGCTGGAGAAGCTGACGTCCAGACCAAAGCATTTACTGGTATTTATCAACCCGTTTGGAGGAA
AAGGACAAGGCAAGCGGATATATGAAAGAAAAGTGGCACCACTGTTCACCTTAGCCTCCATCACCACTGACATCATCGTTACTGAACATG
CTAATCAGGCCAAGGAGACTCTGTATGAGATTAACATAGACAAATACGACGGCATCGTCTGTGTCGGCGGAGATGGTATGTTCAGCGAGG
TGCTGCACGGTCTGATTGGGAGGACGCAGAGGAGCGCCGGGGTCGACCAGAACCACCCCCGGGCTGTGCTGGTCCCCAGTAGCCTCCGGA
TTGGAATCATTCCCGCAGTAACCTGTAATTATGGAAACGGAGGCTGCCAGCACAGCTGTGAGGACACAGACACAGGCCCCACGTGTGGTT
GCCACCAGAAGTACGCCCTCCACTCAGACGGTCGCACGTGCATCGAGACGTGCGCAGTCAATAACGGAGGCTGCGACCGGACATGCAAGG
ACACAGCCACTGGCGTGCGATGCAGCTGCCCCGTTGGATTCACACTGCAGCCGGACGGGAAGACATGCAAAGACATCAACGAGTGCCTGG
TCAACAACGGAGGCTGCGACCACTTCTGCCGCAACACCGTGGGCAGCTTCGAGTGCGGCTGCCGGAAGGGCTACAAGCTGCTCACCGACG
AGCGCACCTGCCAGGACATCGACGAGTGCTCCTTCGAGCGGACCTGTGACCACATCTGCATCAACTCCCCGGGCAGCTTCCAGTGCCTGT
GTCACCGCGGCTACATCCTCTACGGGACAACCCACTGCGGAGATGTGGACGAGTGCAGCATGAGCAACGGGAGCTGTGACCAGGGCTGCG
TCAACACCAAGGGCAGCTACGAGTGCGTCTGTCCCCCGGGGAGGCGGCTCCACTGGAACGGGAAGGATTGCGTGGAGACAGGCAAGTGTC
TTTCTCGCGCCAAGACCTCCCCCCGGGCCCAGCTGTCCTGCAGCAAGGCAGGCGGTGTGGAGAGCTGCTTCCTTTCCTGCCCGGCTCACA
CACTCTTCGTGCCAGACTCGGAAAATAGCTACGTCCTGAGCTGCGGAGTTCCAGGGCCGCAGGGCAAGGCGCTGCAGAAACGCAACGGCA
CCAGCTCTGGCCTCGGGCCCAGCTGCTCAGATGCCCCCACCACCCCCATCAAACAGAAGGCCCGCTTCAAGATCCGAGATGCCAAGTGCC
ACCTCCGGCCCCACAGCCAGGCACGAGCAAAGGAGACCGCCAGGCAGCCGCTGCTGGACCACTGCCATGTGACTTTCGTGACCCTCAAGT
GTGACTCCTCCAAGAAGAGGCGCCGTGGCCGCAAGTCCCCATCCAAGGAGGTGTCCCACATCACAGCAGAGTTTGAGATCGAGACAAAGA
TGGAAGAGGCCTCAGACACATGCGAAGCGGACTGCTTGCGGAAGCGAGCAGAACAGAGCCTGCAGGCCGCCATCAAGACCCTGCGCAAGT
CCATCGGCCGGCAGCAGTTCTATGTCCAGGTCTCAGGCACTGAGTACGAGGTAGCCCAGAGGCCAGCCAAGGCGCTGGAGGGGCAGGGGG
CATGTGGCGCAGGCCAGGTGCTACAGGACAGCAAATGCGTTGCCTGTGGGCCTGGCACCCACTTCGGTGGTGAGCTCGGCCAGTGTGTGT
CATGTATGCCAGGAACATACCAGGACATGGAAGGCCAGCTCAGTTGCACACCGTGCCCCAGCAGCGACGGGCTTGGTCTGCCTGGTGCCC
GCAACGTGTCGGAATGTGGAGGCCAGTGTTCTCCAGGCTTCTTCTCGGCCGATGGCTTCAAGCCCTGCCAGGCCTGCCCCGTGGGCACGT
ACCAGCCTGAGCCCGGGCGCACCGGCTGCTTCCCCTGTGGAGGGGGTTTGCTCACCAAACACGAAGGCACCACCTCCTTCCAGGACTGCG
AGGCTAAAGTGCACTGCTCCCCCGGCCACCACTACAACACCACCACCCACCGCTGCATCCGCTGCCCCGTCGGCACCTACCAGCCCGAGT
TTGGCCAGAACCACTGCATCACCTGTCCGGGCAACACCAGCACAGACTTCGATGGCTCCACCAACGTCACACACTGCAAAAACCAGCACT
GCGGCGGCGAGCTTGGTGACTACACCGGCTACATCGAGTCCCCCAACTACCCTGGCGACTACCCAGCCAACGCTGAATGCGTCTGGCACA
TCGCGCCTCCCCCAAAGCGCAGGATCCTCATCGTGGTCCCTGAGATCTTCCTGCCCATCGAGGATGAGTGCGGCGATGTTCTGGTCATGA
GGAAGAGTGCCTCTCCCACGTCCATCACCACCTATGAGACCTGCCAGACCTACGAGAGGCCCATCGCCTTCACCTCCCGCTCCCGCAAGC
TCTGGATCCAGTTCAAATCCAATGAAGGCAACAGCGGCAAAGGCTTCCAAGTGCCCTATGTCACCTACGATGAGGACTACCAGCAACTCA
TAGAGGACATCGTGCGCGATGGGCGCCTGTACGCCTCGGAGAACCACCAGGAAATTTTGAAAGACAAGAAGCTGATCAAGGCCCTCTTCG
ACGTGCTGGCGCATCCCCAGAACTACTTCAAGTACACAGCCCAGGAATCCAAGGAGATGTTCCCACGGTCCTTCATCAAACTGCTGCGCT
CCAAAGTGTCTCGGTTCCTGCGGCCCTACAAATAACCGGGGGGAGCGGCCCTGCCTGGGGGTGGCCTGGTCCGCGGAGGGTGCACCTGCC
CTCCACAGTGGGAGCTGCATGGGCCTCCACACCACCTTGGGAACCCCATGGCACTGCCCTTCAGGGAAGCCGACCAGCCCATGGAGACCG
AGCCCAGGCACCCTTCGGACCCGCTGCCCCTGTGGGAGCACCCTGCTTCAGGAAGCCTCCCTCCCTCCCTCTGCCTCCCTTCCCCAGGAC
ACCAAGAGCGCCCTCTCCTGAGCCCTGGCAGACCGACTGCAGGTAGCAGGATTGCAGGACCCTCTGCCTGGCCTGGCGTTTCAGGAGAGA
GGGGAAGTGGGGCCTGTGCTCTGGGAGGCGTGGTCATCCGAGACAGGAGTCCAGGGGAGAGAGGAGGGGACAAAGGCGCCGTCTGGGGGA
GGTCGATGAGCCTGTGCTGGCATCCGCGGGCCCCACGCTTTGCCAACTCCTCCAGCCACAGGCAAGGCCACGGCTCCGGGCTGTTGCGCT
CTAAGGGTTCTGTGATTGGATGGAACAGAGCTGCTGGGGAGGAGACTGGAAGTTTCTGCATTCCTTCAACAGAACATTTAATGAAGTACT
CTATATATATATATAAATATATATATAAATATATATATATACTTCTATTTGTGGGTACTTTAGGAAAATGCCCTTTGGTCACTGTAAATA
TGAATTGTGACCCCATCCCTTCCCGCATGAGCCCAGTGAGTCCCAGCAGCTATCAGCCTCCCTGAACGATTAAACAGCTCCTCCCAGCAT
TTGCATTTGCCCTTCTGTTTCTGTGAGGCCGGCAGCCCTTGGGGCTGGGGAGAGCACAGCTTGCCTTGGACTTGCTTCTGAACACGAATT
CTTCGAGAACTAGGCTCAGATGCTCTGCTGGAGTGTTGGCCTCACCCCAGTCCCCTTGCCAGCAACATCACTGCCCTTGGACGAGACTCA
GTGGAAGACACTTCCCCTCGGACCCGTTCCCAGGAGGTGCAGGGGCCCAGCAATAAACGGCGAAAGGGGCCTTGGCTCTTGCCCTGTGGC
AGTGACCTTGGGGTCCGTACTATGCCCAGGTGTCAGCAGGAAACAAGGCCTTGCTCACAGGAGCACAGGCTGTACCACCACAAGGAGCCT
CAGAGCGGCCAGTGAGGAAAGGGGAGAGAGCAGAGCTTGCTGTCAGAGGCCAGGCTCCCAGTGCAGCCTCCTCTTGCTACGCCATGCCAC
CCCCATTCACAGGGAAACCTCTTTCCTTCCTATAAAGGAAAGAGGTTGAATTGACTCACATTTCCACATGGCTTGGGAGGCCTCAGGAAA
CTTACAATCATGGCGGAGGGTGAAGGGGAAGCAAGCGCCTTCTTCACAAGGCAGCAGGAGAGAGAAGCAAGCAGGGAAATGTCGGGAGAA
AGAGAGTCTGGGCTGTGACCGAGTGCATGTGTCCCACCCAGCCGGAAGGCCAGCGCCTGGGATGGAGCCAGCAGAACCCCATGCCGAGGT
CCAGGAGGCCTTGCCTGCTCTTCATCTGCCTGCGAGCTGTAGGACCTGCATGGGAAATGGTCTGTGTGTTTCAGGTTAACAAATACTGAA
AATCCCAAGGAACCTGGGAGAATCTGAAAATGAACTCCAGTCTTCAGCTCGAAGTTGCCTCTAGGGTTCCTCCTGGTCACCCCCGGGCCC
AGCCTGGCTGGCGAGAAACAAACACGGTTTGAGAGGCTGTGGCACACTGAGGACCACACAGATGGAGGCAGCCAAGTGAGGTCCCTGGAG
GTTCAGGGCTTGGTGACGAGGTAGGCCGTGATCACATATTCTACAGTCCAAAAGAGGGCCCGGAGCTCAGCAATTACTCACGCCGTCACA
TGTGCCCACAGTAGCGGGCTCCGCGGCGTGGCTCCTGCTGCCATCAGCTGCCTTCTCTGCTGAAGTCCAACTCAAGTCGGAGAGAGAGTG
GAGCCTCTGCACTTGGGGAGTAGGTCAGTGTCAACTAACAAGCCCTGCCAGGGGCCACTGCCGCTCCTCTGGTCACAGTCCACGCAGGCC
AGCCCTGGTTTCTGGAAAGAGGCCTCCCTCCCTCCCTTTGTGGAGCCGTCAGTCATCCCCAAGATGAGAGGCGAGCATCCTGCCGAGTGA
GCCTGCAGCAACAGCTCCTGAGGAAGGTGCCGGGAGGGGTGTCGCCTCTTCACGAGTGTTCTCCAGAGAATCAGAACCCAGAGGATACAG
ACGTAGATGTGTGAGGGGCTGCATTATGGGAACTGGCTCACAGATTCTGGAGGCCAACAAGTCCCACGATCGGCTGTCTGCGATTGGGAG
ACCAGGAGAAGCCACACCGTAACTCAGTCTGAGTCCAAAGCCCGAGAAGCCAGGGGCCACCCTGTGAGTCCCAGCATCCAAAGCCCCGAG
AACGAGGAAGATGGATGTCCCAGCTCCCAAAGGGAGGATTCTCCCTTCCTCCTCCTTCTTTTCTATTGGGGCCCTCAACAGATTGGATGG
AGTGGATGTCTTCACTCAGTCTGCCAATTCCCATCCTAACCTCTTCTGGAAACACCCTAGCATGTTTTCCCAGCTAGCTGGGTATCCGTT
CACCCAACCAAGACGACCATGCAATCAACCATCACACTTAAATGTTTTTGTTTTGTTTTTTTTGTTTTGTTTTTTGTTTTCTTTTTTTGT
TTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTTGGTTCACTGCA
AGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCACCTTGCCCGGCTAATTT
TTTTGTATTTTTAGTAGAGACAGGGTTTCACCATATTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCC
AAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAGCCAGGGTTTTCTTTTTTAATCCTTTCCAGAAACAGAAAGAGCTCTTAACCTC
TCTGAGCTCTTTCTGCAATTCCTTTGGGCGATTTCTGAAAGTTGCCACCCACGTACTCACAGATCCACTGCCCGCCTCTCCTCCCCTCAT
GTTCCAGGACTCACCACCGTGGTCAGACCATGCCCAGTGTGCCCAGGGCAAAGTTGGATGGGCAGGTGCAGACGAGGCCCAGCCTTCATC
CTGCTTTCCCTCGCAAGCCCTTCTATAGCTCCCAGCCCACGGGAGAGGCCATGAGGAGCGCGAGGTCGCCAGCAGCCCCACTGGGCCTCC
CACACCATCTGAGTGACTTGAATTCCAGGGTTGGGCTCTGTCTTGAGTCTCCACATCAGTCTCACACCAGGGAACTTGGGGGTCCCCCGT
TAAACTACAGCTGACCCTGGGCCTCAGGGCGGGATGGTCCCAAGGTGAGCTCCGTGGACAGCAAAGCGCATTTCTTCCAGTTGGCATGTT
GTCGAAGCCAATGGCAGCTTGACTGATGTGAGGTGGCTATTCCACCTGGTTCAAGATGGAGGTGTAGAGAAAAGGGAAGTGGGGAACAAG
GACTGGGCCAGGTAGGACGGATCCACGTAACGAGGCCCAAGAAAAAATGGAAGCTGGGGGCAGAGAGTCCAGGAGGCCCCCATGCTGTCT
GAGGGGAGGCCGGCATAGCCCCTCCTCGACTGTCGCCTGAGCAGCTGATGAGGTCCCCAGCGCCGCACGCTGTGCTCCAGGGAGAGGAGC
CAAGAAGCAAGCGGGCTGCTGGGAGTCCCTGCACTGCCATCTGGCCGGGACGGAGGCGCCTGCCCGGTCTCCAGGCTCCTCTGAGCTTGG
GTCAGCTCCTAATGGAGCATGGCACCCCAGGGAACCAGAGGAACTCTGTGAAGAAAGGCATGGAAAACCGGGGTGTCTCCCGCACAGCTT
CCCAGGAGTCAGGTGGGACCCAGGCGTGGGGGGACCTTTCTGCCCCACATTCCTGGCATTCCCCCCAAGTTTATTTCTACTTTCCAGAAA
CAAGCCACGGGAAGGGAAGGAACCTGCAGCAGGGTTTCGAAGACAGCCAGGCCCTCCGTGATTGAGGGCTCATATAGCCGCTGAGGGCAG
CCTGCAGCCAGGTGGCCTCACCTGCTGCCCAGAATTAGGCTGTGCCTTTTCCCAGTCCTTCCCCATGCCAGAGCCTCTCCCCATCTTTCC
CCGCGCCAGAGCCTCACAGCCACAGCCACACCAACCTCCCTCCTCTCAAGCAGCAGAATCAGCCTACGCTCCCCAGCCTCAGTGCCCCTG
CCCCACACAGGTCACGCTGGCAAGGCGATGACCAGTTTCCGAAACGCTGGATCCCCAAGGGTACAGTGTGGCCCAGTCCTCCCCCACCTC
CATGGTGGCCCAGGCTGCAGGGCTCACGGTGGGCCCACGGTGGAGGCCTCAGGCAGCTTTCTCTCCAGCTACCCATTGGCTTAGGACACA
CAGATAAAGTAGAGCTGAAACACGGGCCAAAACATCCCCAGACAAGGATGGCACAAGAGGCCAAATTTGAAGGCCTTGGGAGAGAAGCCA
TTTCCCCTACCTCTAACGAGCGTAGTTTTCTGTCTGAATGGCCCCCCTTTTCATGCACGCTCGTTCTTAAGAGACGCACCATCCGCAGGC
AGCGTCTCAGTGAAGCCTGTCCCCTGGGCTTGTCCACGGCAGGAGGCCCCTGGCCTGTTTAAGCCATACCGATGCTTAATTTACATTTTT
GGAGTTGAATATTATTCCGGTGCCTCCACCACCCCCAGCAGAAAAAATAAGATACTGAAATAAGTTGAGTCATTTCGCAAACATTTACTG
AGCACCTCCTGTGTGCCAGGCTCCTAGAAAGACAGGGAGTTGGTGCCCTGCACAGATGACAAACTGCCCCAGACAGCAGACAGACAAACA
AACTGCCCCGGACAGCAGACAGACAAACAGACACATTGCCCTGGACAGCAGAGAGACAAACAGACACACTGCCCCGGACAGCAGACAGAC
AGACACGTTGCCCCGGACAGCAGACAGAAAAACTGCCCCGGACAGCAGACAGACAGACAAACTGCCCCAGACAGCAGACAGACAAACTGC
CCCGGAAAGCAGACAGCAAACTGCCCCAGACAGCAGACAGACAGACACACTTCCCCAGACAGCAGATAGACAGACACCCTGCCCCAGACA
GCAGACAAGCTGCCCTGGACAGCCTGCTCACCTTGCCTGCCACAGTGCATGCCCCACAGGGAGAAGCCTTCCTTCTCACCCAGGGAGTCC
AGCCATTTTCACCTCCCCTGGTCCATGCTCAGGAAGTCTGGTCACCCTGGCAAACTGCACCTGACATTGAGGTCCCTTTTCACCAAAGAT
GCACAAGGTGTCCATGCCGAGCCGACATCATTCAGGCCAAGGGCAGAGGATGTAATGAGGGGTGGAGTGAGGATGTGGAGAGAGAGCAGA
GAGCGCCTCCTATTCTACCGCGGCTGCCTCTGCCCCCACAGCACCCACAGATCCCTGGCCCTTCCAGGAGTAAGTCCTGGGCAGGCAGAG
CTGGGGTTGGCCTGATCCCACCTGCCTTGCTCTTGGAAAGGACATCAGGTGTGGGCAAAGCATCCTTGAAGCCCAGACAACACAGGCATG
GCCTGCGTGCCCTCCCAGCATCTGCTGCGATGGCCTCAAGGCCTCTCCAGTCCCCTGCTGCACCATGCCACTCAGAGCCCCTGAGTGAGC
CCCCTGGAATTGTCTGCACCCCCCAAGCCCCAACAGGAAGAAGGGAAAGGTGGGGAAGCTGACGCTCACTCAGTGCCCACTGGGTGCCAG
GCTCTGGGCTCAACCCTCTAATATCCACACATTCCATCCCCCCAGCCCCATGTAGATGGTGGGGTTAAGACCATTCTTCAGATGTGGAAA
TGAAGGCTCTGGGAGACCACAGGACATGCCCAAGGCAAAGAGTTGGTAGTCCCTGGATTTGGGAATCAAACTCAAGCCCATCTAATCCAA
GGGTAGGAAATGTCTCTAAAACGTTGATCAATCTGAAGCTTACAGATTGGAAACTGGGCCAGGTCAGCCCTGGCGGTGGAGTCCAGAGAC
AGAGAGAAGGCTGCAGGGAGGGGAGAGAACAGGAGGATCCCGGGCCAGGGTGACTTCAGTGACATTCCTTCCCTCCTTCACAAGCACGAA
AAACTCGTTCGGAGAAAAGACAGCTTCTGCCTTCCCTACCAGGCGGACAGGGTACTCACTGTGCCGACGTGAGCAGACACAGCCAGAGGC
TCAAGTGCCCTTGCCGAGTGTCCCCACTGCTCTTGGGGAGGCCCCGGCACAGCCCTGCAGAGATGCAAGTAAGAGAGTGCCCAGTGCCCT
CGGCAGATGGGTGGCAGAAAGCAGGAGGAGGAAGAGGGAGCTGACCGATGCCGGGTGTCTTACTCCGCTGAGATCAGAACCTCCAACATG
CCGAGCAGACGCAGGCCACATTGCTCGGGGAACAGGACACCAGGGCGCTGTGCTAGCGGCCCGCAGACTTCACTTCTGGCTCCTGTGAGG
GCACTGTATTGTCCAGACGCTTGGCAACGACTCTGCCTGCAAGTGGCAAATACCAACATAACCACATCTTCCTTTTAGTTGCCACAAATA

>15964_15964_2_CERK-SCUBE1_CERK_chr22_47103740_ENST00000216264_SCUBE1_chr22_43654341_ENST00000360835_length(amino acids)=1023AA_BP=0
MGATGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEETDVHGKHQGSGKWQKMEKPYAFTVHCVK
RARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL
YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAVTCNYGNGGCQHSCEDTDTGPTCGCHQKYALH
SDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDID
ECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSP
RAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLRPHSQA
RAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFY
VQVSGTEYEVAQRPAKALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGG
QCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCIT
CPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTS
ITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQN

--------------------------------------------------------------
>15964_15964_3_CERK-SCUBE1_CERK_chr22_47103740_ENST00000541677_SCUBE1_chr22_43654341_ENST00000290460_length(transcript)=2296nt_BP=710nt
GTCCGGCGCCCCTCGGCGTCCGCGCGCCCCCAGCCTGGCGGACGAGCCCGGCGGCGGAGATGGGGGCGACGGGGGCGGCGGAGCCGCTGC
AATCCGTGCTGTGGGTGAAGCAGCAGCGCTGCGCCGTGAGCCTGGAGCCCGCGCGGGCTCTGCTGCGCTGGTGGCGGAGCCCGGGGCCCG
GAGCCGGCGCCCCCGGCGCGGATGCCTGCTCTGTGCCTGTATCTGAGATCATCGCCGTTGAGGAAACAGACGTTCACGGGAAACATCAAG
GCAGTGGAAAATGGCAGAAAATGGAAAAGCCTTACGCTTTTACAGTTCACTGTGTAAAGAGAGCACGACGGCACCGCTGGAAGTGGGCGC
AGGTGACTTTCTGGTGTCCAGAGGAGCAGCTGTGTCACTTGTGGCTGCAGACCCTGCGGGAGATGCTGGAGAAGCTGACGTCCAGACCAA
AGCATTTACTGGTATTTATCAACCCGTTTGGAGGAAAAGGACAAGGCAAGCGGATATATGAAAGAAAAGTGGCACCACTGTTCACCTTAG
CCTCCATCACCACTGACATCATCGCATCGTCTGTGTCGGCGGAGATGGTATGTTCAGCGAGGTGCTGCACGGTCTGATTGGGAGGACGCA
GAGGAGCGCCGGGGTCGACCAGAACCACCCCCGGGCTGTGCTGGTCCCCAGTAGCCTCCGGATTGGAATCATTCCCGCAGTAACCTGTAA
TTATGGAAACGGAGGCTGCCAGCACAGCTGTGAGGACACAGACACAGGCCCCACGTGTGGTTGCCACCAGAAGTACGCCCTCCACTCAGA
CGGTCGCACGTGCATCGAGAAGGATGAGGCTGCAATTGAGCGCTCTCAGTTCAATGCCACGTCAGTAGCTGATGTGGACAAGCGGGTGAA
ACGGCGGCTACTCATGGAGACGTGCGCAGTCAATAACGGAGGCTGCGACCGGACATGCAAGGACACAGCCACTGGCGTGCGATGCAGCTG
CCCCGTTGGATTCACACTGCAGCCGGACGGGAAGACATGCAAAGGTCAGCATGTGGAGCTGTGTGGGTGCCCCTGCCTGTACTGGCCTGG
CCAAGAGCCTCCGTGTGCTTGCATAGCCGGGCCCAGGGCTGGGCTGAACGGGGGCCACGTGTAGCTGTGGGAAAGGACACGTGGCAATCA
TTTGCTTTGCTGTTGGAGAGGCCAGGAAGAGGGAGGGCTGGCCAGCAGCAGGGTCCCCAGCAGAGTTCGAGAGAACACAGGTCCCACGGC
ACATCAGCAGGTTCCTGGGCCAAAAAGGCACTGATGTCAGAGAATTTGGCTGCACGCTGGGTTAAACAGTTAAGCCAGCGTCTCTACTGT
GGGACTTCCTGGGCCCTCAGTGATAGTGTGGCTTCCCAAGGCGCGTAGAATGTAGCGCGTTTCCGAACCCCTTGACCTTTGGTTGCAGTG
GGTCTTGCAGAGCTGATGGGGACAGTCTGGTGTTGGGCCATCTGGGACACACAGGTCTACTCATGCCAGGAAAAATAAGGACAGTGTGTC
ACTACTAGGGGGGCGAGGCTAGGGGGATCCCATCTGAAAAGATAAGGACTCAGGACTTCTGCTTGCCATCAGAAAATGAGGAGTCAGGAA
GACCTGAGAGTGACTGGTTGAAGGAAGGAGGGACAGGGCTGGCCTGCTGGTGGCTGGCAGTGAGGGAAGGCAGAGGTGTATCCTCCCACT
TGTCCCCTGAGTCACCCCACAAAGACTTACTGAGTACCTCCTGGGTTGAGGGGACCCTCAGGAAACAGGAAGCCCAGGGAGCTGGGAGAG
GAGAGCTGGGTGGGCTCTCGAGACAGCCCTGCAGATGAGGAGGTCCAGCTACCCCCAAAGGACAGACGGAGCCCCAAGAAGCTGTGGGCC
CTGGGGCAGGGTGTTAGGCCTGAGTGCCGGAGCCCTCTGTGCAGAAGGGTGAGGGGCAGTGCTCAGTGCCCCCAGCATCACTCCAGACCA
CCCTCCAAACGCCCCCACCCCAGCGCTGGGCAGTACCCCCACACTCTGCCAGGAAGGGAGAGCCTAGAGAGCAGGGCGTGGAGGGGAGAG
GAACTGGAACTTCCAAAGTCCCATCGGGGAAAATATTGAAAGTGGAGGTTAGGGTGACTTAAAATAGCTTGAGGTGGACTTTTTTTAAGC
CTGTAAAAATAAATGTATTTTTGTACAGTGTATGACTTCTTCCTTGCCAACTTGCTGGGAAGAACCGAGTGATTATTGACAGAAATAACA

>15964_15964_3_CERK-SCUBE1_CERK_chr22_47103740_ENST00000541677_SCUBE1_chr22_43654341_ENST00000290460_length(amino acids)=185AA_BP=
MGATGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEETDVHGKHQGSGKWQKMEKPYAFTVHCVK
RARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIASSVSAEMVCSA

--------------------------------------------------------------
>15964_15964_4_CERK-SCUBE1_CERK_chr22_47103740_ENST00000541677_SCUBE1_chr22_43654341_ENST00000360835_length(transcript)=9781nt_BP=710nt
GTCCGGCGCCCCTCGGCGTCCGCGCGCCCCCAGCCTGGCGGACGAGCCCGGCGGCGGAGATGGGGGCGACGGGGGCGGCGGAGCCGCTGC
AATCCGTGCTGTGGGTGAAGCAGCAGCGCTGCGCCGTGAGCCTGGAGCCCGCGCGGGCTCTGCTGCGCTGGTGGCGGAGCCCGGGGCCCG
GAGCCGGCGCCCCCGGCGCGGATGCCTGCTCTGTGCCTGTATCTGAGATCATCGCCGTTGAGGAAACAGACGTTCACGGGAAACATCAAG
GCAGTGGAAAATGGCAGAAAATGGAAAAGCCTTACGCTTTTACAGTTCACTGTGTAAAGAGAGCACGACGGCACCGCTGGAAGTGGGCGC
AGGTGACTTTCTGGTGTCCAGAGGAGCAGCTGTGTCACTTGTGGCTGCAGACCCTGCGGGAGATGCTGGAGAAGCTGACGTCCAGACCAA
AGCATTTACTGGTATTTATCAACCCGTTTGGAGGAAAAGGACAAGGCAAGCGGATATATGAAAGAAAAGTGGCACCACTGTTCACCTTAG
CCTCCATCACCACTGACATCATCGCATCGTCTGTGTCGGCGGAGATGGTATGTTCAGCGAGGTGCTGCACGGTCTGATTGGGAGGACGCA
GAGGAGCGCCGGGGTCGACCAGAACCACCCCCGGGCTGTGCTGGTCCCCAGTAGCCTCCGGATTGGAATCATTCCCGCAGTAACCTGTAA
TTATGGAAACGGAGGCTGCCAGCACAGCTGTGAGGACACAGACACAGGCCCCACGTGTGGTTGCCACCAGAAGTACGCCCTCCACTCAGA
CGGTCGCACGTGCATCGAGACGTGCGCAGTCAATAACGGAGGCTGCGACCGGACATGCAAGGACACAGCCACTGGCGTGCGATGCAGCTG
CCCCGTTGGATTCACACTGCAGCCGGACGGGAAGACATGCAAAGACATCAACGAGTGCCTGGTCAACAACGGAGGCTGCGACCACTTCTG
CCGCAACACCGTGGGCAGCTTCGAGTGCGGCTGCCGGAAGGGCTACAAGCTGCTCACCGACGAGCGCACCTGCCAGGACATCGACGAGTG
CTCCTTCGAGCGGACCTGTGACCACATCTGCATCAACTCCCCGGGCAGCTTCCAGTGCCTGTGTCACCGCGGCTACATCCTCTACGGGAC
AACCCACTGCGGAGATGTGGACGAGTGCAGCATGAGCAACGGGAGCTGTGACCAGGGCTGCGTCAACACCAAGGGCAGCTACGAGTGCGT
CTGTCCCCCGGGGAGGCGGCTCCACTGGAACGGGAAGGATTGCGTGGAGACAGGCAAGTGTCTTTCTCGCGCCAAGACCTCCCCCCGGGC
CCAGCTGTCCTGCAGCAAGGCAGGCGGTGTGGAGAGCTGCTTCCTTTCCTGCCCGGCTCACACACTCTTCGTGCCAGACTCGGAAAATAG
CTACGTCCTGAGCTGCGGAGTTCCAGGGCCGCAGGGCAAGGCGCTGCAGAAACGCAACGGCACCAGCTCTGGCCTCGGGCCCAGCTGCTC
AGATGCCCCCACCACCCCCATCAAACAGAAGGCCCGCTTCAAGATCCGAGATGCCAAGTGCCACCTCCGGCCCCACAGCCAGGCACGAGC
AAAGGAGACCGCCAGGCAGCCGCTGCTGGACCACTGCCATGTGACTTTCGTGACCCTCAAGTGTGACTCCTCCAAGAAGAGGCGCCGTGG
CCGCAAGTCCCCATCCAAGGAGGTGTCCCACATCACAGCAGAGTTTGAGATCGAGACAAAGATGGAAGAGGCCTCAGACACATGCGAAGC
GGACTGCTTGCGGAAGCGAGCAGAACAGAGCCTGCAGGCCGCCATCAAGACCCTGCGCAAGTCCATCGGCCGGCAGCAGTTCTATGTCCA
GGTCTCAGGCACTGAGTACGAGGTAGCCCAGAGGCCAGCCAAGGCGCTGGAGGGGCAGGGGGCATGTGGCGCAGGCCAGGTGCTACAGGA
CAGCAAATGCGTTGCCTGTGGGCCTGGCACCCACTTCGGTGGTGAGCTCGGCCAGTGTGTGTCATGTATGCCAGGAACATACCAGGACAT
GGAAGGCCAGCTCAGTTGCACACCGTGCCCCAGCAGCGACGGGCTTGGTCTGCCTGGTGCCCGCAACGTGTCGGAATGTGGAGGCCAGTG
TTCTCCAGGCTTCTTCTCGGCCGATGGCTTCAAGCCCTGCCAGGCCTGCCCCGTGGGCACGTACCAGCCTGAGCCCGGGCGCACCGGCTG
CTTCCCCTGTGGAGGGGGTTTGCTCACCAAACACGAAGGCACCACCTCCTTCCAGGACTGCGAGGCTAAAGTGCACTGCTCCCCCGGCCA
CCACTACAACACCACCACCCACCGCTGCATCCGCTGCCCCGTCGGCACCTACCAGCCCGAGTTTGGCCAGAACCACTGCATCACCTGTCC
GGGCAACACCAGCACAGACTTCGATGGCTCCACCAACGTCACACACTGCAAAAACCAGCACTGCGGCGGCGAGCTTGGTGACTACACCGG
CTACATCGAGTCCCCCAACTACCCTGGCGACTACCCAGCCAACGCTGAATGCGTCTGGCACATCGCGCCTCCCCCAAAGCGCAGGATCCT
CATCGTGGTCCCTGAGATCTTCCTGCCCATCGAGGATGAGTGCGGCGATGTTCTGGTCATGAGGAAGAGTGCCTCTCCCACGTCCATCAC
CACCTATGAGACCTGCCAGACCTACGAGAGGCCCATCGCCTTCACCTCCCGCTCCCGCAAGCTCTGGATCCAGTTCAAATCCAATGAAGG
CAACAGCGGCAAAGGCTTCCAAGTGCCCTATGTCACCTACGATGAGGACTACCAGCAACTCATAGAGGACATCGTGCGCGATGGGCGCCT
GTACGCCTCGGAGAACCACCAGGAAATTTTGAAAGACAAGAAGCTGATCAAGGCCCTCTTCGACGTGCTGGCGCATCCCCAGAACTACTT
CAAGTACACAGCCCAGGAATCCAAGGAGATGTTCCCACGGTCCTTCATCAAACTGCTGCGCTCCAAAGTGTCTCGGTTCCTGCGGCCCTA
CAAATAACCGGGGGGAGCGGCCCTGCCTGGGGGTGGCCTGGTCCGCGGAGGGTGCACCTGCCCTCCACAGTGGGAGCTGCATGGGCCTCC
ACACCACCTTGGGAACCCCATGGCACTGCCCTTCAGGGAAGCCGACCAGCCCATGGAGACCGAGCCCAGGCACCCTTCGGACCCGCTGCC
CCTGTGGGAGCACCCTGCTTCAGGAAGCCTCCCTCCCTCCCTCTGCCTCCCTTCCCCAGGACACCAAGAGCGCCCTCTCCTGAGCCCTGG
CAGACCGACTGCAGGTAGCAGGATTGCAGGACCCTCTGCCTGGCCTGGCGTTTCAGGAGAGAGGGGAAGTGGGGCCTGTGCTCTGGGAGG
CGTGGTCATCCGAGACAGGAGTCCAGGGGAGAGAGGAGGGGACAAAGGCGCCGTCTGGGGGAGGTCGATGAGCCTGTGCTGGCATCCGCG
GGCCCCACGCTTTGCCAACTCCTCCAGCCACAGGCAAGGCCACGGCTCCGGGCTGTTGCGCTCTAAGGGTTCTGTGATTGGATGGAACAG
AGCTGCTGGGGAGGAGACTGGAAGTTTCTGCATTCCTTCAACAGAACATTTAATGAAGTACTCTATATATATATATAAATATATATATAA
ATATATATATATACTTCTATTTGTGGGTACTTTAGGAAAATGCCCTTTGGTCACTGTAAATATGAATTGTGACCCCATCCCTTCCCGCAT
GAGCCCAGTGAGTCCCAGCAGCTATCAGCCTCCCTGAACGATTAAACAGCTCCTCCCAGCATTTGCATTTGCCCTTCTGTTTCTGTGAGG
CCGGCAGCCCTTGGGGCTGGGGAGAGCACAGCTTGCCTTGGACTTGCTTCTGAACACGAATTCTTCGAGAACTAGGCTCAGATGCTCTGC
TGGAGTGTTGGCCTCACCCCAGTCCCCTTGCCAGCAACATCACTGCCCTTGGACGAGACTCAGTGGAAGACACTTCCCCTCGGACCCGTT
CCCAGGAGGTGCAGGGGCCCAGCAATAAACGGCGAAAGGGGCCTTGGCTCTTGCCCTGTGGCAGTGACCTTGGGGTCCGTACTATGCCCA
GGTGTCAGCAGGAAACAAGGCCTTGCTCACAGGAGCACAGGCTGTACCACCACAAGGAGCCTCAGAGCGGCCAGTGAGGAAAGGGGAGAG
AGCAGAGCTTGCTGTCAGAGGCCAGGCTCCCAGTGCAGCCTCCTCTTGCTACGCCATGCCACCCCCATTCACAGGGAAACCTCTTTCCTT
CCTATAAAGGAAAGAGGTTGAATTGACTCACATTTCCACATGGCTTGGGAGGCCTCAGGAAACTTACAATCATGGCGGAGGGTGAAGGGG
AAGCAAGCGCCTTCTTCACAAGGCAGCAGGAGAGAGAAGCAAGCAGGGAAATGTCGGGAGAAAGAGAGTCTGGGCTGTGACCGAGTGCAT
GTGTCCCACCCAGCCGGAAGGCCAGCGCCTGGGATGGAGCCAGCAGAACCCCATGCCGAGGTCCAGGAGGCCTTGCCTGCTCTTCATCTG
CCTGCGAGCTGTAGGACCTGCATGGGAAATGGTCTGTGTGTTTCAGGTTAACAAATACTGAAAATCCCAAGGAACCTGGGAGAATCTGAA
AATGAACTCCAGTCTTCAGCTCGAAGTTGCCTCTAGGGTTCCTCCTGGTCACCCCCGGGCCCAGCCTGGCTGGCGAGAAACAAACACGGT
TTGAGAGGCTGTGGCACACTGAGGACCACACAGATGGAGGCAGCCAAGTGAGGTCCCTGGAGGTTCAGGGCTTGGTGACGAGGTAGGCCG
TGATCACATATTCTACAGTCCAAAAGAGGGCCCGGAGCTCAGCAATTACTCACGCCGTCACATGTGCCCACAGTAGCGGGCTCCGCGGCG
TGGCTCCTGCTGCCATCAGCTGCCTTCTCTGCTGAAGTCCAACTCAAGTCGGAGAGAGAGTGGAGCCTCTGCACTTGGGGAGTAGGTCAG
TGTCAACTAACAAGCCCTGCCAGGGGCCACTGCCGCTCCTCTGGTCACAGTCCACGCAGGCCAGCCCTGGTTTCTGGAAAGAGGCCTCCC
TCCCTCCCTTTGTGGAGCCGTCAGTCATCCCCAAGATGAGAGGCGAGCATCCTGCCGAGTGAGCCTGCAGCAACAGCTCCTGAGGAAGGT
GCCGGGAGGGGTGTCGCCTCTTCACGAGTGTTCTCCAGAGAATCAGAACCCAGAGGATACAGACGTAGATGTGTGAGGGGCTGCATTATG
GGAACTGGCTCACAGATTCTGGAGGCCAACAAGTCCCACGATCGGCTGTCTGCGATTGGGAGACCAGGAGAAGCCACACCGTAACTCAGT
CTGAGTCCAAAGCCCGAGAAGCCAGGGGCCACCCTGTGAGTCCCAGCATCCAAAGCCCCGAGAACGAGGAAGATGGATGTCCCAGCTCCC
AAAGGGAGGATTCTCCCTTCCTCCTCCTTCTTTTCTATTGGGGCCCTCAACAGATTGGATGGAGTGGATGTCTTCACTCAGTCTGCCAAT
TCCCATCCTAACCTCTTCTGGAAACACCCTAGCATGTTTTCCCAGCTAGCTGGGTATCCGTTCACCCAACCAAGACGACCATGCAATCAA
CCATCACACTTAAATGTTTTTGTTTTGTTTTTTTTGTTTTGTTTTTTGTTTTCTTTTTTTGTTTTCTTTTTTTTTTTTTTTTTTTTTTTT
GAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTTGGTTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTC
TCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCACCACCTTGCCCGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTT
CACCATATTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCA
CCACGCCCAGCCAGGGTTTTCTTTTTTAATCCTTTCCAGAAACAGAAAGAGCTCTTAACCTCTCTGAGCTCTTTCTGCAATTCCTTTGGG
CGATTTCTGAAAGTTGCCACCCACGTACTCACAGATCCACTGCCCGCCTCTCCTCCCCTCATGTTCCAGGACTCACCACCGTGGTCAGAC
CATGCCCAGTGTGCCCAGGGCAAAGTTGGATGGGCAGGTGCAGACGAGGCCCAGCCTTCATCCTGCTTTCCCTCGCAAGCCCTTCTATAG
CTCCCAGCCCACGGGAGAGGCCATGAGGAGCGCGAGGTCGCCAGCAGCCCCACTGGGCCTCCCACACCATCTGAGTGACTTGAATTCCAG
GGTTGGGCTCTGTCTTGAGTCTCCACATCAGTCTCACACCAGGGAACTTGGGGGTCCCCCGTTAAACTACAGCTGACCCTGGGCCTCAGG
GCGGGATGGTCCCAAGGTGAGCTCCGTGGACAGCAAAGCGCATTTCTTCCAGTTGGCATGTTGTCGAAGCCAATGGCAGCTTGACTGATG
TGAGGTGGCTATTCCACCTGGTTCAAGATGGAGGTGTAGAGAAAAGGGAAGTGGGGAACAAGGACTGGGCCAGGTAGGACGGATCCACGT
AACGAGGCCCAAGAAAAAATGGAAGCTGGGGGCAGAGAGTCCAGGAGGCCCCCATGCTGTCTGAGGGGAGGCCGGCATAGCCCCTCCTCG
ACTGTCGCCTGAGCAGCTGATGAGGTCCCCAGCGCCGCACGCTGTGCTCCAGGGAGAGGAGCCAAGAAGCAAGCGGGCTGCTGGGAGTCC
CTGCACTGCCATCTGGCCGGGACGGAGGCGCCTGCCCGGTCTCCAGGCTCCTCTGAGCTTGGGTCAGCTCCTAATGGAGCATGGCACCCC
AGGGAACCAGAGGAACTCTGTGAAGAAAGGCATGGAAAACCGGGGTGTCTCCCGCACAGCTTCCCAGGAGTCAGGTGGGACCCAGGCGTG
GGGGGACCTTTCTGCCCCACATTCCTGGCATTCCCCCCAAGTTTATTTCTACTTTCCAGAAACAAGCCACGGGAAGGGAAGGAACCTGCA
GCAGGGTTTCGAAGACAGCCAGGCCCTCCGTGATTGAGGGCTCATATAGCCGCTGAGGGCAGCCTGCAGCCAGGTGGCCTCACCTGCTGC
CCAGAATTAGGCTGTGCCTTTTCCCAGTCCTTCCCCATGCCAGAGCCTCTCCCCATCTTTCCCCGCGCCAGAGCCTCACAGCCACAGCCA
CACCAACCTCCCTCCTCTCAAGCAGCAGAATCAGCCTACGCTCCCCAGCCTCAGTGCCCCTGCCCCACACAGGTCACGCTGGCAAGGCGA
TGACCAGTTTCCGAAACGCTGGATCCCCAAGGGTACAGTGTGGCCCAGTCCTCCCCCACCTCCATGGTGGCCCAGGCTGCAGGGCTCACG
GTGGGCCCACGGTGGAGGCCTCAGGCAGCTTTCTCTCCAGCTACCCATTGGCTTAGGACACACAGATAAAGTAGAGCTGAAACACGGGCC
AAAACATCCCCAGACAAGGATGGCACAAGAGGCCAAATTTGAAGGCCTTGGGAGAGAAGCCATTTCCCCTACCTCTAACGAGCGTAGTTT
TCTGTCTGAATGGCCCCCCTTTTCATGCACGCTCGTTCTTAAGAGACGCACCATCCGCAGGCAGCGTCTCAGTGAAGCCTGTCCCCTGGG
CTTGTCCACGGCAGGAGGCCCCTGGCCTGTTTAAGCCATACCGATGCTTAATTTACATTTTTGGAGTTGAATATTATTCCGGTGCCTCCA
CCACCCCCAGCAGAAAAAATAAGATACTGAAATAAGTTGAGTCATTTCGCAAACATTTACTGAGCACCTCCTGTGTGCCAGGCTCCTAGA
AAGACAGGGAGTTGGTGCCCTGCACAGATGACAAACTGCCCCAGACAGCAGACAGACAAACAAACTGCCCCGGACAGCAGACAGACAAAC
AGACACATTGCCCTGGACAGCAGAGAGACAAACAGACACACTGCCCCGGACAGCAGACAGACAGACACGTTGCCCCGGACAGCAGACAGA
AAAACTGCCCCGGACAGCAGACAGACAGACAAACTGCCCCAGACAGCAGACAGACAAACTGCCCCGGAAAGCAGACAGCAAACTGCCCCA
GACAGCAGACAGACAGACACACTTCCCCAGACAGCAGATAGACAGACACCCTGCCCCAGACAGCAGACAAGCTGCCCTGGACAGCCTGCT
CACCTTGCCTGCCACAGTGCATGCCCCACAGGGAGAAGCCTTCCTTCTCACCCAGGGAGTCCAGCCATTTTCACCTCCCCTGGTCCATGC
TCAGGAAGTCTGGTCACCCTGGCAAACTGCACCTGACATTGAGGTCCCTTTTCACCAAAGATGCACAAGGTGTCCATGCCGAGCCGACAT
CATTCAGGCCAAGGGCAGAGGATGTAATGAGGGGTGGAGTGAGGATGTGGAGAGAGAGCAGAGAGCGCCTCCTATTCTACCGCGGCTGCC
TCTGCCCCCACAGCACCCACAGATCCCTGGCCCTTCCAGGAGTAAGTCCTGGGCAGGCAGAGCTGGGGTTGGCCTGATCCCACCTGCCTT
GCTCTTGGAAAGGACATCAGGTGTGGGCAAAGCATCCTTGAAGCCCAGACAACACAGGCATGGCCTGCGTGCCCTCCCAGCATCTGCTGC
GATGGCCTCAAGGCCTCTCCAGTCCCCTGCTGCACCATGCCACTCAGAGCCCCTGAGTGAGCCCCCTGGAATTGTCTGCACCCCCCAAGC
CCCAACAGGAAGAAGGGAAAGGTGGGGAAGCTGACGCTCACTCAGTGCCCACTGGGTGCCAGGCTCTGGGCTCAACCCTCTAATATCCAC
ACATTCCATCCCCCCAGCCCCATGTAGATGGTGGGGTTAAGACCATTCTTCAGATGTGGAAATGAAGGCTCTGGGAGACCACAGGACATG
CCCAAGGCAAAGAGTTGGTAGTCCCTGGATTTGGGAATCAAACTCAAGCCCATCTAATCCAAGGGTAGGAAATGTCTCTAAAACGTTGAT
CAATCTGAAGCTTACAGATTGGAAACTGGGCCAGGTCAGCCCTGGCGGTGGAGTCCAGAGACAGAGAGAAGGCTGCAGGGAGGGGAGAGA
ACAGGAGGATCCCGGGCCAGGGTGACTTCAGTGACATTCCTTCCCTCCTTCACAAGCACGAAAAACTCGTTCGGAGAAAAGACAGCTTCT
GCCTTCCCTACCAGGCGGACAGGGTACTCACTGTGCCGACGTGAGCAGACACAGCCAGAGGCTCAAGTGCCCTTGCCGAGTGTCCCCACT
GCTCTTGGGGAGGCCCCGGCACAGCCCTGCAGAGATGCAAGTAAGAGAGTGCCCAGTGCCCTCGGCAGATGGGTGGCAGAAAGCAGGAGG
AGGAAGAGGGAGCTGACCGATGCCGGGTGTCTTACTCCGCTGAGATCAGAACCTCCAACATGCCGAGCAGACGCAGGCCACATTGCTCGG
GGAACAGGACACCAGGGCGCTGTGCTAGCGGCCCGCAGACTTCACTTCTGGCTCCTGTGAGGGCACTGTATTGTCCAGACGCTTGGCAAC
GACTCTGCCTGCAAGTGGCAAATACCAACATAACCACATCTTCCTTTTAGTTGCCACAAATATTCAGTTTTGTTTTATCCATCATGTCCC

>15964_15964_4_CERK-SCUBE1_CERK_chr22_47103740_ENST00000541677_SCUBE1_chr22_43654341_ENST00000360835_length(amino acids)=825AA_BP=40
MFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAVTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCD
RTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGS
FQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLS
CPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQPLLDHCHVTF
VTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAKAL
EGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQAC
PVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHC
KNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTS
RSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFI

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Fusion Gene PPI Analysis for CERK-SCUBE1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CERK-SCUBE1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CERK-SCUBE1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource