FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CHD1-MTOR (FusionGDB2 ID:16279)

Fusion Gene Summary for CHD1-MTOR

check button Fusion gene summary
Fusion gene informationFusion gene name: CHD1-MTOR
Fusion gene ID: 16279
HgeneTgene
Gene symbol

CHD1

MTOR

Gene ID

1105

2475

Gene namechromodomain helicase DNA binding protein 1mechanistic target of rapamycin kinase
SynonymsCHD-1|PILBOSFRAP|FRAP1|FRAP2|RAFT1|RAPT1|SKS
Cytomap

5q15-q21.1

1p36.22

Type of geneprotein-codingprotein-coding
Descriptionchromodomain-helicase-DNA-binding protein 1ATP-dependent helicase CHD1serine/threonine-protein kinase mTORFK506 binding protein 12-rapamycin associated protein 2FK506-binding protein 12-rapamycin complex-associated protein 1FKBP-rapamycin associated proteinFKBP12-rapamycin complex-associated protein 1mammalian target o
Modification date2020031320200329
UniProtAcc.

TLDC1

Ensembl transtripts involved in fusion geneENST00000284049, ENST00000511067, 
ENST00000376838, ENST00000495435, 
ENST00000361445, 
Fusion gene scores* DoF score14 X 15 X 8=168012 X 11 X 8=1056
# samples 1919
** MAII scorelog2(19/1680*10)=-3.14438990933518
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1056*10)=-2.47453851102751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CHD1 [Title/Abstract] AND MTOR [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCHD1(98199112)-MTOR(11273623), # samples:4
Anticipated loss of major functional domain due to fusion event.CHD1-MTOR seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CHD1-MTOR seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMTOR

GO:0001558

regulation of cell growth

18762023

TgeneMTOR

GO:0001934

positive regulation of protein phosphorylation

20233713

TgeneMTOR

GO:0006468

protein phosphorylation

12150926|15467718|18925875

TgeneMTOR

GO:0009267

cellular response to starvation

28223137

TgeneMTOR

GO:0010507

negative regulation of autophagy

30704899

TgeneMTOR

GO:0016242

negative regulation of macroautophagy

25327288

TgeneMTOR

GO:0016310

phosphorylation

11853878|25327288

TgeneMTOR

GO:0031667

response to nutrient levels

29750193

TgeneMTOR

GO:0034198

cellular response to amino acid starvation

22424946

TgeneMTOR

GO:0038202

TORC1 signaling

28223137

TgeneMTOR

GO:0043200

response to amino acid

18497260

TgeneMTOR

GO:0045727

positive regulation of translation

18762023

TgeneMTOR

GO:0046777

protein autophosphorylation

15467718

TgeneMTOR

GO:0071230

cellular response to amino acid stimulus

22424946

TgeneMTOR

GO:0071233

cellular response to leucine

22424946

TgeneMTOR

GO:1990253

cellular response to leucine starvation

22424946


check buttonFusion gene breakpoints across CHD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MTOR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LAMLTCGA-AB-2939-03ACHD1chr5

98199112

-MTORchr1

11273623

-
ChimerDB4LAMLTCGA-AB-2939_61FFWAAXX_7CHD1chr5

98199112

-MTORchr1

11273623

-
ChimerDB4LAMLTCGA-AB-2939_61FFWAAXX_7CHD1chr5

98204199

-MTORchr1

11273623

-
ChimerDB4LAMLTCGA-AB-2939_704G6AAXX_7CHD1chr5

98199112

-MTORchr1

11273623

-
ChimerDB4LAMLTCGA-AB-2939CHD1chr5

98199111

-MTORchr1

11273623

-


Top

Fusion Gene ORF analysis for CHD1-MTOR

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000284049ENST00000376838CHD1chr5

98199112

-MTORchr1

11273623

-
5CDS-intronENST00000284049ENST00000376838CHD1chr5

98204199

-MTORchr1

11273623

-
5CDS-intronENST00000284049ENST00000376838CHD1chr5

98199111

-MTORchr1

11273623

-
5CDS-intronENST00000284049ENST00000495435CHD1chr5

98199112

-MTORchr1

11273623

-
5CDS-intronENST00000284049ENST00000495435CHD1chr5

98204199

-MTORchr1

11273623

-
5CDS-intronENST00000284049ENST00000495435CHD1chr5

98199111

-MTORchr1

11273623

-
5CDS-intronENST00000511067ENST00000376838CHD1chr5

98199112

-MTORchr1

11273623

-
5CDS-intronENST00000511067ENST00000376838CHD1chr5

98199111

-MTORchr1

11273623

-
5CDS-intronENST00000511067ENST00000495435CHD1chr5

98199112

-MTORchr1

11273623

-
5CDS-intronENST00000511067ENST00000495435CHD1chr5

98199111

-MTORchr1

11273623

-
5UTR-3CDSENST00000511067ENST00000361445CHD1chr5

98204199

-MTORchr1

11273623

-
5UTR-intronENST00000511067ENST00000376838CHD1chr5

98204199

-MTORchr1

11273623

-
5UTR-intronENST00000511067ENST00000495435CHD1chr5

98204199

-MTORchr1

11273623

-
Frame-shiftENST00000284049ENST00000361445CHD1chr5

98199112

-MTORchr1

11273623

-
Frame-shiftENST00000284049ENST00000361445CHD1chr5

98199111

-MTORchr1

11273623

-
Frame-shiftENST00000511067ENST00000361445CHD1chr5

98199112

-MTORchr1

11273623

-
Frame-shiftENST00000511067ENST00000361445CHD1chr5

98199111

-MTORchr1

11273623

-
In-frameENST00000284049ENST00000361445CHD1chr5

98204199

-MTORchr1

11273623

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000284049CHD1chr598204199-ENST00000361445MTORchr111273623-9881439815089302926

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for CHD1-MTOR


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CHD1-MTOR


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:98199112/chr1:11273623)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MTOR

TLDC1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.456

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035117_13714161711.0Compositional biasNote=Ser-rich
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-30351_7014161711.0Compositional biasNote=Ser-rich
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035272_36414161711.0DomainChromo 1
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035389_45214161711.0DomainChromo 2
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035493_66314161711.0DomainHelicase ATP-binding
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035792_94314161711.0DomainHelicase C-terminal
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035614_61714161711.0MotifNote=DEAH box
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-3035506_51314161711.0Nucleotide bindingATP
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581382_198210392550.0DomainFAT
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519582182_251610392550.0DomainPI3K/PI4K
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519582517_254910392550.0DomainFATC
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581069_110510392550.0RepeatNote=HEAT 26
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581106_114410392550.0RepeatNote=HEAT 27
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581145_118810392550.0RepeatNote=HEAT 28
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581189_122510392550.0RepeatNote=HEAT 29
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581226_127310392550.0RepeatNote=HEAT 30
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581274_131110392550.0RepeatNote=HEAT 31
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581312_134510392550.0RepeatNote=HEAT 32
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581346_138210392550.0RepeatNote=TPR 1
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581383_140810392550.0RepeatNote=TPR 2
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581409_144210392550.0RepeatNote=TPR 3
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581443_147310392550.0RepeatNote=TPR 4
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581474_150710392550.0RepeatNote=TPR 5
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581508_154110392550.0RepeatNote=TPR 6
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581542_157410392550.0RepeatNote=TPR 7
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581575_161410392550.0RepeatNote=TPR 8
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581615_164910392550.0RepeatNote=TPR 9
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581650_169310392550.0RepeatNote=TPR 10
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581694_173110392550.0RepeatNote=TPR 11
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581732_178610392550.0RepeatNote=TPR 12
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581787_184610392550.0RepeatNote=TPR 13
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581898_193010392550.0RepeatNote=TPR 14
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581931_197010392550.0RepeatNote=TPR 15
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581971_200510392550.0RepeatNote=TPR 16

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-30351628_164414161711.0RegionNote=3 X 5 AA repeats of H-S-D-H-R
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-30351628_163214161711.0RepeatNote=1
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-30351634_163814161711.0RepeatNote=2
HgeneCHD1chr5:98204199chr1:11273623ENST00000284049-30351640_164414161711.0RepeatNote=3
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958100_13710392550.0RepeatNote=HEAT 3
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581029_106810392550.0RepeatNote=HEAT 25
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958138_17910392550.0RepeatNote=HEAT 4
TgeneMTORchr5:98204199chr1:11273623ENST00000361445195816_5310392550.0RepeatNote=HEAT 1
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958180_22010392550.0RepeatNote=HEAT 5
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958222_27610392550.0RepeatNote=HEAT 6
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958277_31310392550.0RepeatNote=HEAT 7
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958314_36410392550.0RepeatNote=HEAT 8
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958365_40910392550.0RepeatNote=HEAT 9
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958410_44510392550.0RepeatNote=HEAT 10
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958446_49410392550.0RepeatNote=HEAT 11
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958495_52910392550.0RepeatNote=HEAT 12
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958530_56310392550.0RepeatNote=HEAT 13
TgeneMTORchr5:98204199chr1:11273623ENST00000361445195855_9910392550.0RepeatNote=HEAT 2
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958564_59610392550.0RepeatNote=HEAT 14
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958597_63610392550.0RepeatNote=HEAT 15
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958637_68310392550.0RepeatNote=HEAT 16
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958686_72410392550.0RepeatNote=HEAT 17
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958727_76610392550.0RepeatNote=HEAT 18
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958769_81110392550.0RepeatNote=HEAT 19
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958814_85310392550.0RepeatNote=HEAT 20
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958857_89310392550.0RepeatNote=HEAT 21
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958894_94210392550.0RepeatNote=HEAT 22
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958943_98810392550.0RepeatNote=HEAT 23
TgeneMTORchr5:98204199chr1:11273623ENST000003614451958989_102710392550.0RepeatNote=HEAT 24


Top

Fusion Gene Sequence for CHD1-MTOR


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16279_16279_1_CHD1-MTOR_CHD1_chr5_98204199_ENST00000284049_MTOR_chr1_11273623_ENST00000361445_length(transcript)=9881nt_BP=4398nt
AGGTGAATCAAAGGAGAGTCCCAGAAAACCTGTGACTGTTGAAGAAAATTCATCTGTGAATTTTTATATTCAAGGAGTCAGTATTTATAT
TCATCTTTTAAACTGGGAAGATTTATATTTTACTTTAAAACTTCTTGATAATAATTTACAATGAATGGACACAGTGATGAAGAAAGTGTT
AGAAACAGTAGTGGAGAATCAAGCCAGTCGGATGATGATTCTGGGTCAGCTTCAGGCTCTGGATCTGGTTCGAGTTCTGGAAGCAGTAGT
GATGGAAGCAGTAGCCAGTCAGGTAGCAGTGACTCTGACTCCGGATCTGAATCAGGCAGTCAGTCAGAGTCTGAGTCAGACACTTCCCGA
GAAAACAAAGTTCAAGCAAAACCACCGAAAGTTGATGGAGCTGAGTTTTGGAAATCTAGTCCTAGTATTCTGGCCGTTCAGAGATCTGCA
ATCCTCAAGAAGCAGCAACAGCAGCAGCAGCAACAACAACATCAAGCCTCATCTAATAGCGGATCAGAAGAGGATTCCTCTAGCAGTGAA
GATTCCGATGACTCATCAAGTGAGGTCAAAAGGAAAAAGCATAAAGATGAAGATTGGCAAATGTCTGGGTCAGGATCTCCATCTCAGTCT
GGTTCAGATTCAGAATCTGAAGAAGAGAGAGAGAAAAGCAGTTGTGATGAAACAGAATCTGATTATGAGCCAAAAAACAAAGTCAAAAGC
AGAAAACCTCAAAATAGATCTAAGTCAAAAAATGGAAAGAAGATTCTTGGACAAAAAAAGAGACAGATTGATTCATCTGAGGAGGATGAT
GATGAAGAAGATTATGATAATGATAAAAGAAGTTCTCGTCGCCAAGCAACTGTTAATGTTAGCTATAAGGAGGATGAAGAAATGAAAACA
GATTCTGATGACCTACTGGAAGTCTGTGGAGAGGATGTTCCTCAACCTGAGGAAGAGGAATTTGAAACCATAGAAAGATTTATGGATTGT
CGGATTGGGAGAAAAGGAGCTACTGGTGCTACTACAACCATCTATGCAGTTGAAGCAGATGGTGACCCAAATGCAGGCTTTGAAAAAAAC
AAAGAACCAGGAGAGATTCAGTATTTAATTAAATGGAAAGGATGGTCCCATATCCACAACACTTGGGAGACAGAAGAAACCCTCAAGCAG
CAGAATGTTAGAGGAATGAAAAAATTGGATAATTATAAGAAAAAAGATCAGGAAACAAAAAGATGGTTGAAAAATGCCTCTCCAGAAGAT
GTGGAATATTATAATTGCCAGCAAGAACTTACAGATGATCTACATAAACAGTATCAAATAGTGGAACGTATAATTGCTCATTCCAATCAA
AAGTCAGCAGCTGGTTATCCTGATTATTACTGCAAATGGCAGGGCCTTCCATACTCAGAGTGCAGCTGGGAAGATGGAGCTCTCATTTCC
AAAAAGTTTCAAGCATGCATTGATGAGTATTTTAGCAGGAACCAATCAAAAACCACTCCTTTTAAAGATTGCAAAGTATTAAAACAAAGG
CCAAGGTTTGTAGCCCTGAAGAAGCAGCCATCCTATATTGGAGGACATGAGGGCTTAGAATTAAGAGATTATCAACTGAATGGTTTAAAT
TGGCTTGCTCATTCTTGGTGCAAAGGAAATAGTTGCATACTCGCTGATGAAATGGGCCTTGGAAAAACAATACAGACGATCTCATTTCTG
AATTATTTGTTTCATGAACATCAATTATATGGACCTTTTTTATTGGTAGTACCGCTCTCCACTCTTACTTCCTGGCAAAGGGAAATTCAG
ACTTGGGCTTCTCAAATGAATGCTGTGGTTTATTTAGGTGACATTAACAGCAGAAACATGATAAGAACTCATGAATGGACGCATCATCAG
ACCAAACGGTTAAAATTTAATATATTGTTAACAACTTATGAAATTTTATTAAAAGATAAGGCATTCCTTGGAGGTCTAAATTGGGCATTT
ATAGGTGTTGATGAAGCACACCGATTAAAGAATGATGACTCCCTTCTGTATAAAACTTTAATAGATTTTAAATCCAATCATCGTCTCCTT
ATCACTGGAACTCCTCTACAGAATTCCCTCAAAGAGCTCTGGTCTTTGCTACATTTCATTATGCCAGAAAAGTTTTCTTCCTGGGAAGAT
TTTGAAGAAGAACATGGCAAAGGGAGAGAATATGGTTATGCAAGCCTTCACAAGGAGCTTGAGCCATTTCTGTTACGCCGAGTTAAGAAA
GATGTGGAAAAATCTCTTCCTGCCAAGGTTGAGCAGATTTTAAGAATGGAAATGAGTGCTTTACAGAAACAATATTACAAATGGATTTTA
ACTAGGAATTACAAAGCCCTCAGCAAAGGTTCCAAGGGCAGTACCTCAGGCTTTTTGAACATTATGATGGAGCTAAAGAAATGTTGTAAC
CATTGCTACCTCATTAAACCACCAGATAATAATGAATTCTATAATAAACAGGAGGCCTTACAACACTTAATTCGTAGTAGCGGAAAATTG
ATTCTTCTTGACAAGCTATTAATTCGCCTAAGAGAACGAGGCAATCGAGTTCTTATTTTTTCACAAATGGTGCGGATGTTAGATATACTT
GCAGAATATTTGAAATATCGTCAATTCCCCTTTCAAAGATTAGATGGATCAATAAAAGGAGAACTGAGGAAACAAGCTCTAGATCATTTT
AATGCTGAGGGATCAGAGGATTTTTGCTTTTTGCTGTCCACAAGAGCTGGAGGTCTAGGGATTAATTTAGCCTCTGCTGACACTGTTGTT
ATATTTGATTCCGATTGGAATCCACAGAATGATCTTCAGGCACAGGCTAGAGCCCATCGAATTGGGCAAAAGAAACAGGTGAATATTTAT
CGTCTAGTTACAAAGGGATCAGTTGAAGAAGATATTCTTGAAAGGGCGAAAAAGAAGATGGTTTTAGATCATCTTGTAATTCAAAGAATG
GACACAACTGGGAAGACAGTACTACATACAGGTTCTGCCCCATCAAGTTCTACTCCTTTCAATAAAGAAGAGTTATCAGCCATTTTAAAG
TTTGGTGCTGAAGAACTTTTTAAGGAACCTGAAGGAGAAGAACAAGAGCCCCAGGAAATGGATATAGATGAAATCTTGAAGAGAGCTGAA
ACTCATGAAAATGAACCAGGTCCTTTAACTGTAGGAGATGAATTGCTTTCCCAGTTCAAGGTTGCCAACTTCTCAAATATGGATGAGGAT
GACATTGAGTTGGAACCTGAAAGAAATTCAAAGAATTGGGAGGAAATTATTCCAGAAGATCAAAGAAGACGATTAGAAGAAGAAGAAAGA
CAAAAGGAACTTGAAGAAATTTATATGCTCCCAAGAATGAGAAATTGTGCAAAACAGATTAGTTTCAATGGAAGTGAAGGGAGGCGCAGT
AGAAGTAGGAGATACTCTGGATCTGATAGTGATTCCATCTCAGAAGGGAAAAGGCCAAAGAAACGTGGAAGACCACGGACTATTCCTCGG
GAGAATATTAAAGGATTTAGTGATGCAGAAATTAGGCGGTTTATCAAGAGCTATAAGAAATTTGGTGGTCCTCTGGAAAGATTAGATGCA
ATTGCTCGAGATGCTGAGTTAGTTGATAAGTCAGAAACAGACCTTAGACGACTGGGAGAATTGGTACATAATGGTTGCATTAAAGCATTA
AAGGATAGTTCTTCAGGAACAGAACGAACAGGTGGTAGACTCGGAAAAGTGAAGGGTCCAACATTCCGAATATCAGGAGTACAGGTGAAT
GCCAAACTAGTCATCTCCCATGAAGAAGAATTAATACCTTTGCACAAATCCATTCCTTCTGATCCAGAAGAAAGAAAGCAGTATACTATC
CCATGCCACACAAAGGCAGCTCATTTTGATATAGACTGGGGCAAAGAAGATGATTCCAATTTGTTAATTGGCATCTATGAATATGGATAT
GGAAGCTGGGAAATGATTAAAATGGATCCTGACCTCAGTCTAACACACAAGATTCTTCCAGATGATCCCGATAAAAAACCACAAGCAAAA
CAGTTGCAGACCCGTGCAGACTACCTCATCAAATTACTTAGTAGAGATCTTGCAAAAAAAGAAGCTCTTTCTGGTGCGGGAAGTTCAAAG
AGGAGAAAAGCAAGAGCTAAGAAGAATAAAGCAATGAAGTCTATAAAAGTGAAAGAGGAAATAAAGAGTGATTCTTCTCCTCTGCCTTCA
GAGAAGTCTGATGAAGATGATGATAAATTGAGTGAATCCAAGTCTGATGGTAGGGAAAGATCCAAGAAATCTTCAGTGTCAGATGCTCCA
GTTCATATCACGGCAAGTGGTGAACCAGTTCCCATTTCTGAAGAATCTGAAGAGCTGGATCAGAAGACATTCAGCATTGAATTCTGGGTC
ATGAACACCTCAATTCAGAGCACGATCATTCTTCTCATTGAGCAAATTGTGGTAGCTCTTGGGGGTGAATTTAAGCTCTACCTGCCCCAG
CTGATCCCACACATGCTGCGTGTCTTCATGCATGACAACAGCCCAGGCCGCATTGTCTCTATCAAGTTACTGGCTGCAATCCAGCTGTTT
GGCGCCAACCTGGATGACTACCTGCATTTACTGCTGCCTCCTATTGTTAAGTTGTTTGATGCCCCTGAAGCTCCACTGCCATCTCGAAAG
GCAGCGCTAGAGACTGTGGACCGCCTGACGGAGTCCCTGGATTTCACTGACTATGCCTCCCGGATCATTCACCCTATTGTTCGAACACTG
GACCAGAGCCCAGAACTGCGCTCCACAGCCATGGACACGCTGTCTTCACTTGTTTTTCAGCTGGGGAAGAAGTACCAAATTTTCATTCCA
ATGGTGAATAAAGTTCTGGTGCGACACCGAATCAATCATCAGCGCTATGATGTGCTCATCTGCAGAATTGTCAAGGGATACACACTTGCT
GATGAAGAGGAGGATCCTTTGATTTACCAGCATCGGATGCTTAGGAGTGGCCAAGGGGATGCATTGGCTAGTGGACCAGTGGAAACAGGA
CCCATGAAGAAACTGCACGTCAGCACCATCAACCTCCAAAAGGCCTGGGGCGCTGCCAGGAGGGTCTCCAAAGATGACTGGCTGGAATGG
CTGAGACGGCTGAGCCTGGAGCTGCTGAAGGACTCATCATCGCCCTCCCTGCGCTCCTGCTGGGCCCTGGCACAGGCCTACAACCCGATG
GCCAGGGATCTCTTCAATGCTGCATTTGTGTCCTGCTGGTCTGAACTGAATGAAGATCAACAGGATGAGCTCATCAGAAGCATCGAGTTG
GCCCTCACCTCACAAGACATCGCTGAAGTCACACAGACCCTCTTAAACTTGGCTGAATTCATGGAACACAGTGACAAGGGCCCCCTGCCA
CTGAGAGATGACAATGGCATTGTTCTGCTGGGTGAGAGAGCTGCCAAGTGCCGAGCATATGCCAAAGCACTACACTACAAAGAACTGGAG
TTCCAGAAAGGCCCCACCCCTGCCATTCTAGAATCTCTCATCAGCATTAATAATAAGCTACAGCAGCCGGAGGCAGCGGCCGGAGTGTTA
GAATATGCCATGAAACACTTTGGAGAGCTGGAGATCCAGGCTACCTGGTATGAGAAACTGCACGAGTGGGAGGATGCCCTTGTGGCCTAT
GACAAGAAAATGGACACCAACAAGGACGACCCAGAGCTGATGCTGGGCCGCATGCGCTGCCTCGAGGCCTTGGGGGAATGGGGTCAACTC
CACCAGCAGTGCTGTGAAAAGTGGACCCTGGTTAATGATGAGACCCAAGCCAAGATGGCCCGGATGGCTGCTGCAGCTGCATGGGGTTTA
GGTCAGTGGGACAGCATGGAAGAATACACCTGTATGATCCCTCGGGACACCCATGATGGGGCATTTTATAGAGCTGTGCTGGCACTGCAT
CAGGACCTCTTCTCCTTGGCACAACAGTGCATTGACAAGGCCAGGGACCTGCTGGATGCTGAATTAACTGCGATGGCAGGAGAGAGTTAC
AGTCGGGCATATGGGGCCATGGTTTCTTGCCACATGCTGTCCGAGCTGGAGGAGGTTATCCAGTACAAACTTGTCCCCGAGCGACGAGAG
ATCATCCGCCAGATCTGGTGGGAGAGACTGCAGGGCTGCCAGCGTATCGTAGAGGACTGGCAGAAAATCCTTATGGTGCGGTCCCTTGTG
GTCAGCCCTCATGAAGACATGAGAACCTGGCTCAAGTATGCAAGCCTGTGCGGCAAGAGTGGCAGGCTGGCTCTTGCTCATAAAACTTTA
GTGTTGCTCCTGGGAGTTGATCCGTCTCGGCAACTTGACCATCCTCTGCCAACAGTTCACCCTCAGGTGACCTATGCCTACATGAAAAAC
ATGTGGAAGAGTGCCCGCAAGATCGATGCCTTCCAGCACATGCAGCATTTTGTCCAGACCATGCAGCAACAGGCCCAGCATGCCATCGCT
ACTGAGGACCAGCAGCATAAGCAGGAACTGCACAAGCTCATGGCCCGATGCTTCCTGAAACTTGGAGAGTGGCAGCTGAATCTACAGGGC
ATCAATGAGAGCACAATCCCCAAAGTGCTGCAGTACTACAGCGCCGCCACAGAGCACGACCGCAGCTGGTACAAGGCCTGGCATGCGTGG
GCAGTGATGAACTTCGAAGCTGTGCTACACTACAAACATCAGAACCAAGCCCGCGATGAGAAGAAGAAACTGCGTCATGCCAGCGGGGCC
AACATCACCAACGCCACCACTGCCGCCACCACGGCCGCCACTGCCACCACCACTGCCAGCACCGAGGGCAGCAACAGTGAGAGCGAGGCC
GAGAGCACCGAGAACAGCCCCACCCCATCGCCGCTGCAGAAGAAGGTCACTGAGGATCTGTCCAAAACCCTCCTGATGTACACGGTGCCT
GCCGTCCAGGGCTTCTTCCGTTCCATCTCCTTGTCACGAGGCAACAACCTCCAGGATACACTCAGAGTTCTCACCTTATGGTTTGATTAT
GGTCACTGGCCAGATGTCAATGAGGCCTTAGTGGAGGGGGTGAAAGCCATCCAGATTGATACCTGGCTACAGGTTATACCTCAGCTCATT
GCAAGAATTGATACGCCCAGACCCTTGGTGGGACGTCTCATTCACCAGCTTCTCACAGACATTGGTCGGTACCACCCCCAGGCCCTCATC
TACCCACTGACAGTGGCTTCTAAGTCTACCACGACAGCCCGGCACAATGCAGCCAACAAGATTCTGAAGAACATGTGTGAGCACAGCAAC
ACCCTGGTCCAGCAGGCCATGATGGTGAGCGAGGAGCTGATCCGAGTGGCCATCCTCTGGCATGAGATGTGGCATGAAGGCCTGGAAGAG
GCATCTCGTTTGTACTTTGGGGAAAGGAACGTGAAAGGCATGTTTGAGGTGCTGGAGCCCTTGCATGCTATGATGGAACGGGGCCCCCAG
ACTCTGAAGGAAACATCCTTTAATCAGGCCTATGGTCGAGATTTAATGGAGGCCCAAGAGTGGTGCAGGAAGTACATGAAATCAGGGAAT
GTCAAGGACCTCACCCAAGCCTGGGACCTCTATTATCATGTGTTCCGACGAATCTCAAAGCAGCTGCCTCAGCTCACATCCTTAGAGCTG
CAATATGTTTCCCCAAAACTTCTGATGTGCCGGGACCTTGAATTGGCTGTGCCAGGAACATATGACCCCAACCAGCCAATCATTCGCATT
CAGTCCATAGCACCGTCTTTGCAAGTCATCACATCCAAGCAGAGGCCCCGGAAATTGACACTTATGGGCAGCAACGGACATGAGTTTGTT
TTCCTTCTAAAAGGCCATGAAGATCTGCGCCAGGATGAGCGTGTGATGCAGCTCTTCGGCCTGGTTAACACCCTTCTGGCCAATGACCCA
ACATCTCTTCGGAAAAACCTCAGCATCCAGAGATACGCTGTCATCCCTTTATCGACCAACTCGGGCCTCATTGGCTGGGTTCCCCACTGT
GACACACTGCACGCCCTCATCCGGGACTACAGGGAGAAGAAGAAGATCCTTCTCAACATCGAGCATCGCATCATGTTGCGGATGGCTCCG
GACTATGACCACTTGACTCTGATGCAGAAGGTGGAGGTGTTTGAGCATGCCGTCAATAATACAGCTGGGGACGACCTGGCCAAGCTGCTG
TGGCTGAAAAGCCCCAGCTCCGAGGTGTGGTTTGACCGAAGAACCAATTATACCCGTTCTTTAGCGGTCATGTCAATGGTTGGGTATATT
TTAGGCCTGGGAGATAGACACCCATCCAACCTGATGCTGGACCGTCTGAGTGGGAAGATCCTGCACATTGACTTTGGGGACTGCTTTGAG
GTTGCTATGACCCGAGAGAAGTTTCCAGAGAAGATTCCATTTAGACTAACAAGAATGTTGACCAATGCTATGGAGGTTACAGGCCTGGAT
GGCAACTACAGAATCACATGCCACACAGTGATGGAGGTGCTGCGAGAGCACAAGGACAGTGTCATGGCCGTGCTGGAAGCCTTTGTCTAT
GACCCCTTGCTGAACTGGAGGCTGATGGACACAAATACCAAAGGCAACAAGCGATCCCGAACGAGGACGGATTCCTACTCTGCTGGCCAG
TCAGTCGAAATTTTGGACGGTGTGGAACTTGGAGAGCCAGCCCATAAGAAAACGGGGACCACAGTGCCAGAATCTATTCATTCTTTCATT
GGAGACGGTTTGGTGAAACCAGAGGCCCTAAATAAGAAAGCTATCCAGATTATTAACAGGGTTCGAGATAAGCTCACTGGTCGGGACTTC
TCTCATGATGACACTTTGGATGTTCCAACGCAAGTTGAGCTGCTCATCAAACAAGCGACATCCCATGAAAACCTCTGCCAGTGCTATATT
GGCTGGTGCCCTTTCTGGTAACTGGAGGCCCAGATGTGCCCATCACGTTTTTTCTGAGGCTTTTGTACTTTAGTAAATGCTTCCACTAAA
CTGAAACCATGGTGAGAAAGTTTGACTTTGTTAAATATTTTGAAATGTAAATGAAAAGAACTACTGTATATTAAAAGTTGGTTTGAACCA
ACTTTCTAGCTGCTGTTGAAGAATATATTGTCAGAAACACAAGGCTTGATTTGGTTCCCAGGACAGTGAAACATAGTAATACCACGTAAA
TCAAGCCATTCATTTTGGGGAACAGAAGATCCATAACTTTAGAAATACGGGTTTTGACTTAACTCACAAGAGAACTCATCATAAGTACTT
GCTGATGGAAGAATGACCTAGTTGCTCCTCTCAACATGGGTACAGCAAACTCAGCACAGCCAAGAAGCCTCAGGTCGTGGAGAACATGGA
TTAGGATCCTAGACTGTAAAGACACAGAAGATGCTGACCTCACCCCTGCCACCTATCCCAAGACCTCACTGGTCTGTGGACAGCAGCAGA
AATGTTTGCAAGATAGGCCAAAATGAGTACAAAAGGTCTGTCTTCCATCAGACCCAGTGATGCTGCGACTCACACGCTTCAATTCAAGAC
CTGACCGCTAGTAGGGAGGTTTATTCAGATCGCTGGCAGCCTCGGCTGAGCAGATGCACAGAGGGGATCACTGTGCAGTGGGACCACCCT
CACTGGCCTTCTGCAGCAGGGTTCTGGGATGTTTTCAGTGGTCAAAATACTCTGTTTAGAGCAAGGGCTCAGAAAACAGAAATACTGTCA
TGGAGGTGCTGAACACAGGGAAGGTCTGGTACATATTGGAAATTATGAGCAGAACAAATACTCAACTAAATGCACAAAGTATAAAGTGTA

>16279_16279_1_CHD1-MTOR_CHD1_chr5_98204199_ENST00000284049_MTOR_chr1_11273623_ENST00000361445_length(amino acids)=2926AA_BP=1416
MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSS
PSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETES
DYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEE
FETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETK
RWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTP
FKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS
TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTL
IDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSA
LQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIF
SQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHR
IGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEM
DIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQI
SFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGE
LVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSN
LLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEE
IKSDSSPLPSEKSDEDDDKLSESKSDGRERSKKSSVSDAPVHITASGEPVPISEESEELDQKTFSIEFWVMNTSIQSTIILLIEQIVVAL
GGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYAS
RIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGD
ALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQ
QDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKL
QQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMA
RMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVI
QYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVH
PQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHD
RSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDL
SKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTD
IGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEP
LHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGT
YDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTN
SGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRS
LAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDS
VMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CHD1-MTOR


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519582258_22961039.02550.0MLST8


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneMTORchr5:98204199chr1:11273623ENST0000036144519581_6511039.02550.0NBN


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CHD1-MTOR


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CHD1-MTOR


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource