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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CHD7-ASPH (FusionGDB2 ID:16372)

Fusion Gene Summary for CHD7-ASPH

check button Fusion gene summary
Fusion gene informationFusion gene name: CHD7-ASPH
Fusion gene ID: 16372
HgeneTgene
Gene symbol

CHD7

ASPH

Gene ID

55636

444

Gene namechromodomain helicase DNA binding protein 7aspartate beta-hydroxylase
SynonymsCRG|HH5|IS3|KAL5AAH|BAH|CASQ2BP1|FDLAB|HAAH|JCTN|junctin
Cytomap

8q12.2

8q12.3

Type of geneprotein-codingprotein-coding
Descriptionchromodomain-helicase-DNA-binding protein 7ATP-dependent helicase CHD7CHARGE associationchromodomain helicase DNA binding protein 7 isoform CRA_easpartyl/asparaginyl beta-hydroxylaseA beta H-J-JASP beta-hydroxylasecardiac junctinhumbugjunctatepeptide-aspartate beta-dioxygenase
Modification date2020032820200315
UniProtAcc

Q9P2D1

Q6ICH7

Ensembl transtripts involved in fusion geneENST00000423902, ENST00000524602, 
ENST00000525508, ENST00000529472, 
ENST00000356457, ENST00000379449, 
ENST00000389204, ENST00000445642, 
ENST00000517661, ENST00000517847, 
ENST00000517856, ENST00000517903, 
ENST00000518068, ENST00000522603, 
ENST00000522835, ENST00000522919, 
ENST00000523897, ENST00000379454, 
ENST00000541428, 
Fusion gene scores* DoF score12 X 8 X 8=76817 X 17 X 5=1445
# samples 1719
** MAII scorelog2(17/768*10)=-2.17557156458345
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1445*10)=-2.92699816905709
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CHD7 [Title/Abstract] AND ASPH [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCHD7(61655656)-ASPH(62596747), # samples:3
Anticipated loss of major functional domain due to fusion event.CHD7-ASPH seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CHD7-ASPH seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneASPH

GO:0045862

positive regulation of proteolysis

18387192

TgeneASPH

GO:0097202

activation of cysteine-type endopeptidase activity

18387192


check buttonFusion gene breakpoints across CHD7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASPH (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A2KD-01ACHD7chr8

61693989

+ASPHchr8

62416068

-
ChimerDB4BRCATCGA-AR-A1AU-01ACHD7chr8

61655656

-ASPHchr8

62596747

-
ChimerDB4BRCATCGA-AR-A1AU-01ACHD7chr8

61655656

+ASPHchr8

62596747

-


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Fusion Gene ORF analysis for CHD7-ASPH

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000423902ENST00000356457CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000356457CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000379449CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000379449CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000389204CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000389204CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000445642CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000445642CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000517661CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000517661CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000517847CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000517847CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000517856CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000517856CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000517903CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000517903CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000518068CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000518068CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000522603CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000522603CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000522835CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000522835CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000522919CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000522919CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000423902ENST00000523897CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000423902ENST00000523897CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000356457CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000379449CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000389204CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000445642CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000517661CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000517847CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000517856CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000517903CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000518068CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000522603CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000522835CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000522919CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000524602ENST00000523897CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000356457CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000356457CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000379449CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000379449CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000389204CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000389204CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000445642CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000445642CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000517661CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000517661CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000517847CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000517847CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000517856CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000517856CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000517903CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000517903CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000518068CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000518068CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000522603CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000522603CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000522835CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000522835CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000522919CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000522919CHD7chr8

61655656

+ASPHchr8

62596747

-
5CDS-intronENST00000525508ENST00000523897CHD7chr8

61693989

+ASPHchr8

62416068

-
5CDS-intronENST00000525508ENST00000523897CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000423902ENST00000379454CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000423902ENST00000541428CHD7chr8

61693989

+ASPHchr8

62416068

-
Frame-shiftENST00000423902ENST00000541428CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000524602ENST00000379454CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000524602ENST00000541428CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000525508ENST00000379454CHD7chr8

61655656

+ASPHchr8

62596747

-
Frame-shiftENST00000525508ENST00000541428CHD7chr8

61693989

+ASPHchr8

62416068

-
Frame-shiftENST00000525508ENST00000541428CHD7chr8

61655656

+ASPHchr8

62596747

-
In-frameENST00000423902ENST00000379454CHD7chr8

61693989

+ASPHchr8

62416068

-
In-frameENST00000525508ENST00000379454CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-3CDSENST00000524602ENST00000379454CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-3CDSENST00000524602ENST00000541428CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-3CDSENST00000529472ENST00000379454CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-3CDSENST00000529472ENST00000379454CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-3CDSENST00000529472ENST00000541428CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-3CDSENST00000529472ENST00000541428CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000524602ENST00000356457CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000379449CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000389204CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000445642CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000517661CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000517847CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000517856CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000517903CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000518068CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000522603CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000522835CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000522919CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000524602ENST00000523897CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000356457CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000356457CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000379449CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000379449CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000389204CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000389204CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000445642CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000445642CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000517661CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000517661CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000517847CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000517847CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000517856CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000517856CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000517903CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000517903CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000518068CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000518068CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000522603CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000522603CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000522835CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000522835CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000522919CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000522919CHD7chr8

61655656

+ASPHchr8

62596747

-
intron-intronENST00000529472ENST00000523897CHD7chr8

61693989

+ASPHchr8

62416068

-
intron-intronENST00000529472ENST00000523897CHD7chr8

61655656

+ASPHchr8

62596747

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000423902CHD7chr861693989+ENST00000379454ASPHchr862416068-485625754462725759
ENST00000525508CHD7chr861693989+ENST00000379454ASPHchr862416068-4377209602246748

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000423902ENST00000379454CHD7chr861693989+ASPHchr862416068-0.0028848370.99711514
ENST00000525508ENST00000379454CHD7chr861693989+ASPHchr862416068-0.0025614130.99743855

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Fusion Genomic Features for CHD7-ASPH


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CHD7-ASPH


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:61655656/chr8:62596747)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CHD7

Q9P2D1

ASPH

Q6ICH7

FUNCTION: Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production. {ECO:0000269|PubMed:22646239}.FUNCTION: May function as 2-oxoglutarate-dependent dioxygenase. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338151_2226982998.0Compositional biasNote=Gln-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338383_5686982998.0Compositional biasNote=Pro-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212151_2226981139.0Compositional biasNote=Gln-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212383_5686981139.0Compositional biasNote=Pro-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000035645701490_1020314.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST000003794490590_1020204.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST000003892040690_1020226.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST0000044564201690_1020651.6666666666666Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST0000051784701590_1020300.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST0000051790301590_1020299.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST0000051806801390_1020271.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST000005226030590_1020211.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST0000052283501490_1020257.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014111_3120314.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014323_3320314.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000003564570149_290314.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905111_3120204.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905323_3320204.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST00000379449059_290204.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406111_3120226.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406323_3320226.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST00000389204069_290226.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016111_3120651.6666666666666Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016323_3320651.6666666666666Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000004456420169_290651.6666666666666Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015111_3120300.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015323_3320300.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000005178470159_290300.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015111_3120299.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015323_3320299.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000005179030159_290299.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013111_3120271.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013323_3320271.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000005180680139_290271.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305111_3120211.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305323_3320211.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST00000522603059_290211.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014111_3120257.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014323_3320257.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST000005228350149_290257.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014688_6900314.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905688_6900204.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406688_6900226.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016688_6900651.6666666666666Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015688_6900300.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015688_6900299.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013688_6900271.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305688_6900211.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014688_6900257.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325688_690679730.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014341_3740314.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014454_4870314.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014489_5210314.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000356457014525_5570314.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905341_3740204.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905454_4870204.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905489_5210204.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST0000037944905525_5570204.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406341_3740226.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406454_4870226.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406489_5210226.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST0000038920406525_5570226.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016341_3740651.6666666666666RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016454_4870651.6666666666666RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016489_5210651.6666666666666RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000445642016525_5570651.6666666666666RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015341_3740300.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015454_4870300.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015489_5210300.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000517847015525_5570300.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015341_3740299.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015454_4870299.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015489_5210299.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000517903015525_5570299.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013341_3740271.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013454_4870271.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013489_5210271.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000518068013525_5570271.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305341_3740211.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305454_4870211.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305489_5210211.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST0000052260305525_5570211.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014341_3740257.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014454_4870257.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014489_5210257.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST00000522835014525_5570257.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST000003564570141_530314.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000035645701475_7580314.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST00000379449051_530204.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST000003794490575_7580204.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST00000389204061_530226.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST000003892040675_7580226.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST000004456420161_530651.6666666666666Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000044564201675_7580651.6666666666666Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST000005178470151_530300.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000051784701575_7580300.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST000005179030151_530299.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000051790301575_7580299.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST000005180680131_530271.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000051806801375_7580271.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST00000522603051_530211.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST000005226030575_7580211.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST000005228350141_530257.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST0000052283501475_7580257.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST0000035645701454_740314.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST000003794490554_740204.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST000003892040654_740226.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST0000044564201654_740651.6666666666666TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST0000051784701554_740300.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST0000051790301554_740299.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST0000051806801354_740271.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST000005226030554_740211.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST0000052283501454_740257.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3382401_24316982998.0Coiled coilOntology_term=ECO:0000255
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+152401_24310949.0Coiled coilOntology_term=ECO:0000255
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2122401_24316981139.0Coiled coilOntology_term=ECO:0000255
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3381939_19456982998.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3382165_22586982998.0Compositional biasNote=Glu-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3382398_24056982998.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3382726_27366982998.0Compositional biasNote=Poly-Ala
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338597_7186982998.0Compositional biasNote=Lys-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15151_2220949.0Compositional biasNote=Gln-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+151939_19450949.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+152165_22580949.0Compositional biasNote=Glu-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+152398_24050949.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+152726_27360949.0Compositional biasNote=Poly-Ala
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15383_5680949.0Compositional biasNote=Pro-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15597_7180949.0Compositional biasNote=Lys-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2121939_19456981139.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2122165_22586981139.0Compositional biasNote=Glu-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2122398_24056981139.0Compositional biasNote=Poly-Arg
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2122726_27366981139.0Compositional biasNote=Poly-Ala
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212597_7186981139.0Compositional biasNote=Lys-rich
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3381294_14646982998.0DomainHelicase C-terminal
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338800_8676982998.0DomainChromo 1
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338882_9476982998.0DomainChromo 2
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338980_11546982998.0DomainHelicase ATP-binding
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+151294_14640949.0DomainHelicase C-terminal
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15800_8670949.0DomainChromo 1
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15882_9470949.0DomainChromo 2
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15980_11540949.0DomainHelicase ATP-binding
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2121294_14646981139.0DomainHelicase C-terminal
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212800_8676981139.0DomainChromo 1
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212882_9476981139.0DomainChromo 2
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212980_11546981139.0DomainHelicase ATP-binding
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+3381105_11086982998.0MotifNote=DEAH box
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+151105_11080949.0MotifNote=DEAH box
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+2121105_11086981139.0MotifNote=DEAH box
HgeneCHD7chr8:61693989chr8:62416068ENST00000423902+338993_10006982998.0Nucleotide bindingATP
HgeneCHD7chr8:61693989chr8:62416068ENST00000524602+15993_10000949.0Nucleotide bindingATP
HgeneCHD7chr8:61693989chr8:62416068ENST00000525508+212993_10006981139.0Nucleotide bindingATP
TgeneASPHchr8:61693989chr8:62416068ENST00000379454232590_102708759.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST00000541428232590_102679730.0Calcium bindingOntology_term=ECO:0000305
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325111_312708759.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325323_332708759.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST0000037945423259_29708759.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325111_312679730.0Compositional biasNote=Glu-rich
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325323_332679730.0Compositional biasNote=Poly-Lys
TgeneASPHchr8:61693989chr8:62416068ENST0000054142823259_29679730.0Compositional biasNote=Ser-rich
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325688_690708759.0Region2-oxoglutarate binding
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325341_374708759.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325454_487708759.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325489_521708759.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST000003794542325525_557708759.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325341_374679730.0RepeatNote=TPR 1
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325454_487679730.0RepeatNote=TPR 2
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325489_521679730.0RepeatNote=TPR 3
TgeneASPHchr8:61693989chr8:62416068ENST000005414282325525_557679730.0RepeatNote=TPR 4
TgeneASPHchr8:61693989chr8:62416068ENST0000037945423251_53708759.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST00000379454232575_758708759.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST0000054142823251_53679730.0Topological domainCytoplasmic
TgeneASPHchr8:61693989chr8:62416068ENST00000541428232575_758679730.0Topological domainLumenal
TgeneASPHchr8:61693989chr8:62416068ENST00000379454232554_74708759.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneASPHchr8:61693989chr8:62416068ENST00000541428232554_74679730.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for CHD7-ASPH


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16372_16372_1_CHD7-ASPH_CHD7_chr8_61693989_ENST00000423902_ASPH_chr8_62416068_ENST00000379454_length(transcript)=4856nt_BP=2575nt
CGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGCGCGGGGGTTGAGTCGTGGTGGTGCGGACGCGCTCGTGCTCGGGAACTATCGGATTA
AACTTGAATCGAGTGAAATTACACAAAGGAGCGCCGCGGAGGAGGCGGCCCGGGGACCCGGACACCCTGAAACTCACCAGAGACCCGTTC
GCCCCCGGCCAACTCCGTGCCCGTGGATTCAGCCCCCTGGCCGCAGCTGCCGAGCCAACTCCGGAGCCCGCTCTGCGTTTTGTTTTCCCC
TCGGCACTAGGCAGCGGAGGAGCCCGACCGACCCGGACCTATATCCAGACTTTGCCTGACACTGCAGGGTCCAAGAGAATTAAAGAAATA
TGGAATGACATGAAGAAGATTAGTTAAGGATTATAGGCTTTGAGGGCAAACACCTCAGTGAAGTGAAGCACAGGCAAGCTCCTGAGCTGT
GGTTTGGAGGAGCCGTGTGTTGGAAGAAGATGGCAGATCCAGGAATGATGAGTCTTTTTGGCGAGGATGGGAATATTTTCAGTGAAGGTC
TTGAAGGCCTCGGAGAATGTGGTTACCCGGAAAATCCAGTAAATCCTATGGGTCAGCAAATGCCAATAGACCAAGGCTTTGCCTCTTTAC
AGCCATCCCTTCATCATCCTTCAACTAATCAAAATCAAACAAAGCTGACACATTTTGATCACTATAATCAGTATGAACAACAAAAGATGC
ATCTGATGGATCAGCCGAACAGAATGATGAGCAACACCCCTGGGAACGGACTCGCGTCTCCGCACTCGCAGTATCACACCCCTCCCGTTC
CTCAGGTGCCCCATGGTGGCAGTGGTGGCGGTCAGATGGGTGTCTACCCTGGCATGCAGAATGAGAGGCATGGGCAATCCTTTGTGGACA
GCAGCTCCATGTGGGGCCCCAGGGCTGTTCAGGTACCAGACCAGATACGAGCCCCCTACCAGCAGCAGCAGCCACAGCCGCAGCCACCGC
AGCCGGCTCCGTCGGGGCCCCCTGCACAGGGCCACCCTCAGCACATGCAGCAGATGGGCAGCTATATGGCACGTGGGGATTTTTCCATGC
AGCAGCATGGTCAGCCACAGCAGAGGATGAGCCAGTTTTCCCAAGGCCAAGAGGGCCTCAATCAGGGAAATCCTTTTATTGCCACCTCAG
GACCTGGCCACTTGTCCCACGTGCCCCAGCAGAGTCCCAGCATGGCACCTTCCTTGCGTCACTCGGTGCAGCAGTTCCATCACCACCCCT
CTACTGCTCTCCATGGAGAATCCGTTGCCCACAGTCCCAGATTCTCCCCGAATCCTCCCCAACAAGGGGCTGTTAGGCCGCAAACCCTTA
ACTTTAGTTCTCGGAGCCAGACAGTCCCCTCTCCTACTATAAACAACTCAGGGCAGTATTCTCGATATCCTTACAGTAACCTAAATCAGG
GATTAGTTAACAATACAGGGATGAATCAAAATTTAGGCCTTACAAATAATACTCCAATGAATCAGTCCGTACCAAGATACCCCAATGCTG
TAGGATTCCCATCAAACAGTGGTCAAGGACTAATGCACCAGCAGCCCATCCACCCCAGTGGCTCACTTAACCAAATGAACACACAAACTA
TGCATCCTTCACAGCCTCAGGGAACTTATGCCTCTCCACCTCCCATGTCACCCATGAAAGCAATGAGTAATCCAGCAGGCACTCCTCCTC
CACAAGTCAGGCCGGGAAGTGCTGGGATACCAATGGAAGTTGGCAGTTATCCAAATATGCCCCATCCTCAGCCATCTCACCAGCCCCCTG
GTGCCATGGGAATCGGACAGAGGAATATGGGCCCCAGAAACATGCAGCAGTCTCGTCCATTTATAGGCATGTCCTCGGCACCAAGGGAAT
TGACTGGGCACATGAGGCCAAATGGTTGTCCTGGTGTTGGCCTTGGAGACCCACAAGCAATCCAGGAACGACTGATACCTGGCCAACAAC
ATCCTGGTCAACAGCCATCTTTTCAGCAGTTGCCAACCTGTCCTCCACTGCAGCCTCACCCGGGCTTGCACCACCAGTCTTCACCTCCAC
ACCCTCATCACCAGCCTTGGGCACAGCTCCACCCATCACCCCAGAACACCCCGCAGAAAGTGCCTGTGCATCAGCATTCCCCGTCGGAGC
CCTTTCTAGAGAAACCAGTGCCGGATATGACTCAGGTTAGTGGACCGAATGCTCAGCTAGTGAAGAGTGATGATTACCTGCCATCAATAG
AACAGCAGCCACAACAAAAGAAGAAGAAAAAGAAAAACAACCACATTGTAGCAGAGGATCCCAGTAAAGGTTTTGGTAAAGATGACTTCC
CTGGTGGGGTAGATAACCAAGAACTAAATAGGAACTCACTGGATGGGTCCCAAGAAGAAAAAAAGAAAAAGAAAAGGTCAAAGGCAAAAA
AAGACCCGAAGGAACCGAAAGAACCCAAGGAGAAAAAAGAGCCCAAGGAACCCAAGACCCCGAAAGCCCCTAAGATTCCCAAAGAGCCAA
AGGAAAAGAAAGCAAAAACTGCCACGCCAAAACCCAAATCCAGCAAAAAGTCAAGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATG
ACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGC
AGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGG
GTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACAC
TAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTA
AGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATG
TAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACC
ACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCC
CTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCT
ATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATT
GACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCA
AATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGG
TGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGT
GAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCA
AGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGG
CTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAA
TAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTT
TGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCAT
GAATGGCACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTT
ATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAA
ATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAAT
TACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACA
AGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAA
ACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATA
TAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTT

>16372_16372_1_CHD7-ASPH_CHD7_chr8_61693989_ENST00000423902_ASPH_chr8_62416068_ENST00000379454_length(amino acids)=759AA_BP=704
MWFGGAVCWKKMADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQK
MHLMDQPNRMMSNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQP
PQPAPSGPPAQGHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHH
PSTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPN
AVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQP
PGAMGIGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSP
PHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDD
FPGGVDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSRTWEEGKVLIF

--------------------------------------------------------------
>16372_16372_2_CHD7-ASPH_CHD7_chr8_61693989_ENST00000525508_ASPH_chr8_62416068_ENST00000379454_length(transcript)=4377nt_BP=2096nt
ATGGCAGATCCAGGAATGATGAGTCTTTTTGGCGAGGATGGGAATATTTTCAGTGAAGGTCTTGAAGGCCTCGGAGAATGTGGTTACCCG
GAAAATCCAGTAAATCCTATGGGTCAGCAAATGCCAATAGACCAAGGCTTTGCCTCTTTACAGCCATCCCTTCATCATCCTTCAACTAAT
CAAAATCAAACAAAGCTGACACATTTTGATCACTATAATCAGTATGAACAACAAAAGATGCATCTGATGGATCAGCCGAACAGAATGATG
AGCAACACCCCTGGGAACGGACTCGCGTCTCCGCACTCGCAGTATCACACCCCTCCCGTTCCTCAGGTGCCCCATGGTGGCAGTGGTGGC
GGTCAGATGGGTGTCTACCCTGGCATGCAGAATGAGAGGCATGGGCAATCCTTTGTGGACAGCAGCTCCATGTGGGGCCCCAGGGCTGTT
CAGGTACCAGACCAGATACGAGCCCCCTACCAGCAGCAGCAGCCACAGCCGCAGCCACCGCAGCCGGCTCCGTCGGGGCCCCCTGCACAG
GGCCACCCTCAGCACATGCAGCAGATGGGCAGCTATATGGCACGTGGGGATTTTTCCATGCAGCAGCATGGTCAGCCACAGCAGAGGATG
AGCCAGTTTTCCCAAGGCCAAGAGGGCCTCAATCAGGGAAATCCTTTTATTGCCACCTCAGGACCTGGCCACTTGTCCCACGTGCCCCAG
CAGAGTCCCAGCATGGCACCTTCCTTGCGTCACTCGGTGCAGCAGTTCCATCACCACCCCTCTACTGCTCTCCATGGAGAATCCGTTGCC
CACAGTCCCAGATTCTCCCCGAATCCTCCCCAACAAGGGGCTGTTAGGCCGCAAACCCTTAACTTTAGTTCTCGGAGCCAGACAGTCCCC
TCTCCTACTATAAACAACTCAGGGCAGTATTCTCGATATCCTTACAGTAACCTAAATCAGGGATTAGTTAACAATACAGGGATGAATCAA
AATTTAGGCCTTACAAATAATACTCCAATGAATCAGTCCGTACCAAGATACCCCAATGCTGTAGGATTCCCATCAAACAGTGGTCAAGGA
CTAATGCACCAGCAGCCCATCCACCCCAGTGGCTCACTTAACCAAATGAACACACAAACTATGCATCCTTCACAGCCTCAGGGAACTTAT
GCCTCTCCACCTCCCATGTCACCCATGAAAGCAATGAGTAATCCAGCAGGCACTCCTCCTCCACAAGTCAGGCCGGGAAGTGCTGGGATA
CCAATGGAAGTTGGCAGTTATCCAAATATGCCCCATCCTCAGCCATCTCACCAGCCCCCTGGTGCCATGGGAATCGGACAGAGGAATATG
GGCCCCAGAAACATGCAGCAGTCTCGTCCATTTATAGGCATGTCCTCGGCACCAAGGGAATTGACTGGGCACATGAGGCCAAATGGTTGT
CCTGGTGTTGGCCTTGGAGACCCACAAGCAATCCAGGAACGACTGATACCTGGCCAACAACATCCTGGTCAACAGCCATCTTTTCAGCAG
TTGCCAACCTGTCCTCCACTGCAGCCTCACCCGGGCTTGCACCACCAGTCTTCACCTCCACACCCTCATCACCAGCCTTGGGCACAGCTC
CACCCATCACCCCAGAACACCCCGCAGAAAGTGCCTGTGCATCAGCATTCCCCGTCGGAGCCCTTTCTAGAGAAACCAGTGCCGGATATG
ACTCAGGTTAGTGGACCGAATGCTCAGCTAGTGAAGAGTGATGATTACCTGCCATCAATAGAACAGCAGCCACAACAAAAGAAGAAGAAA
AAGAAAAACAACCACATTGTAGCAGAGGATCCCAGTAAAGGTTTTGGTAAAGATGACTTCCCTGGTGGGGTAGATAACCAAGAACTAAAT
AGGAACTCACTGGATGGGTCCCAAGAAGAAAAAAAGAAAAAGAAAAGGTCAAAGGCAAAAAAAGACCCGAAGGAACCGAAAGAACCCAAG
GAGAAAAAAGAGCCCAAGGAACCCAAGACCCCGAAAGCCCCTAAGATTCCCAAAGAGCCAAAGGAAAAGAAAGCAAAAACTGCCACGCCA
AAACCCAAATCCAGCAAAAAGTCAAGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGAT
GCCTCATCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCAT
GAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGA
GTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTC
ATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTAC
CAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTT
GTAATTTTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAG
CTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATAC
TCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAAT
CGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAA
CTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTT
CTGGGGAAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGG
CTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTT
GGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTA
GGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATC
ACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCA
TTCCAAAGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGAT
ATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCA
TTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAAT
TGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGG
TATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTC
TTGAAAAGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGT
AACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCAT
CTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTAC
AGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAA

>16372_16372_2_CHD7-ASPH_CHD7_chr8_61693989_ENST00000525508_ASPH_chr8_62416068_ENST00000379454_length(amino acids)=748AA_BP=693
MADPGMMSLFGEDGNIFSEGLEGLGECGYPENPVNPMGQQMPIDQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHLMDQPNRMM
SNTPGNGLASPHSQYHTPPVPQVPHGGSGGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQ
GHPQHMQQMGSYMARGDFSMQQHGQPQQRMSQFSQGQEGLNQGNPFIATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVA
HSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQG
LMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNM
GPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQPWAQL
HPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELN
RNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSRTWEEGKVLIFDDSFEHEVWQD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CHD7-ASPH


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CHD7-ASPH


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CHD7-ASPH


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource