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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CHSY3-FBXL17 (FusionGDB2 ID:16736)

Fusion Gene Summary for CHSY3-FBXL17

check button Fusion gene summary
Fusion gene informationFusion gene name: CHSY3-FBXL17
Fusion gene ID: 16736
HgeneTgene
Gene symbol

CHSY3

FBXL17

Gene ID

337876

64839

Gene namechondroitin sulfate synthase 3F-box and leucine rich repeat protein 17
SynonymsCHSY2|CSS3FBXO13|Fbl17|Fbx13
Cytomap

5q23.3

5q21.3

Type of geneprotein-codingprotein-coding
Descriptionchondroitin sulfate synthase 3N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3N-acetylgalactosaminyltransferase 3carbohydrate synthase 2chSy-2chondroitin glucuronyltransferase 3chondroitin synthase-2glucuronosyl-N-acetylgalactosF-box/LRR-repeat protein 17F-box only protein 13
Modification date2020031320200313
UniProtAcc

Q70JA7

Q9UF56

Ensembl transtripts involved in fusion geneENST00000507545, ENST00000305031, 
ENST00000359660, ENST00000496714, 
ENST00000542267, 
Fusion gene scores* DoF score9 X 6 X 5=27014 X 13 X 5=910
# samples 1013
** MAII scorelog2(10/270*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/910*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CHSY3 [Title/Abstract] AND FBXL17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCHSY3(129244053)-FBXL17(107684231), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFBXL17

GO:0000209

protein polyubiquitination

27234298

TgeneFBXL17

GO:0006515

protein quality control for misfolded or incompletely synthesized proteins

30190310

TgeneFBXL17

GO:0016567

protein ubiquitination

24035498|30190310

TgeneFBXL17

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

24035498|27234298

TgeneFBXL17

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

30190310


check buttonFusion gene breakpoints across CHSY3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FBXL17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-6822-01ACHSY3chr5

129244053

+FBXL17chr5

107684231

-


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Fusion Gene ORF analysis for CHSY3-FBXL17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000507545ENST00000359660CHSY3chr5

129244053

+FBXL17chr5

107684231

-
3UTR-3CDSENST00000507545ENST00000496714CHSY3chr5

129244053

+FBXL17chr5

107684231

-
3UTR-3CDSENST00000507545ENST00000542267CHSY3chr5

129244053

+FBXL17chr5

107684231

-
In-frameENST00000305031ENST00000359660CHSY3chr5

129244053

+FBXL17chr5

107684231

-
In-frameENST00000305031ENST00000496714CHSY3chr5

129244053

+FBXL17chr5

107684231

-
In-frameENST00000305031ENST00000542267CHSY3chr5

129244053

+FBXL17chr5

107684231

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000305031CHSY3chr5129244053+ENST00000359660FBXL17chr5107684231-486114443582175605
ENST00000305031CHSY3chr5129244053+ENST00000542267FBXL17chr5107684231-485114443582175605
ENST00000305031CHSY3chr5129244053+ENST00000496714FBXL17chr5107684231-483514443582208616

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000305031ENST00000359660CHSY3chr5129244053+FBXL17chr5107684231-0.0003214850.9996785
ENST00000305031ENST00000542267CHSY3chr5129244053+FBXL17chr5107684231-0.0003169320.99968314
ENST00000305031ENST00000496714CHSY3chr5129244053+FBXL17chr5107684231-0.0013840810.99861586

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Fusion Genomic Features for CHSY3-FBXL17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CHSY3-FBXL17


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:129244053/chr5:107684231)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CHSY3

Q70JA7

FBXL17

Q9UF56

FUNCTION: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1. {ECO:0000269|PubMed:12907687}.FUNCTION: Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC) (PubMed:30190310). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (PubMed:30190310). The ability of the SCF(FBXL17) complex to eliminate compromised BTB dimers is required for the differentiation and survival of neural crest and neuronal cells (By similarity). The SCF(FBXL17) complex mediates ubiquitination and degradation of BACH1 (PubMed:24035498, PubMed:30190310). The SCF(FBXL17) complex is also involved in the regulation of the hedgehog/smoothened (Hh) signaling pathway by mediating the ubiquitination and degradation of SUFU, allowing the release of GLI1 from SUFU for proper Hh signal transduction (PubMed:27234298). The SCF(FBXL17) complex mediates ubiquitination and degradation of PRMT1 (By similarity). {ECO:0000250|UniProtKB:B1H1X1, ECO:0000250|UniProtKB:Q9QZN1, ECO:0000269|PubMed:24035498, ECO:0000269|PubMed:27234298, ECO:0000269|PubMed:30190310}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHSY3chr5:129244053chr5:107684231ENST00000305031+23211_235362883.0Compositional biasNote=Pro-rich
HgeneCHSY3chr5:129244053chr5:107684231ENST00000305031+231_7362883.0Topological domainCytoplasmic
HgeneCHSY3chr5:129244053chr5:107684231ENST00000305031+238_28362883.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneFBXL17chr5:129244053chr5:107684231ENST0000035966029216_23660304.0Compositional biasNote=Gly-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST000003596602990_15160304.0Compositional biasNote=Ala-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST0000049671417216_23660315.0Compositional biasNote=Gly-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST000004967141790_15160315.0Compositional biasNote=Ala-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST0000035966029318_36560304.0DomainF-box
TgeneFBXL17chr5:129244053chr5:107684231ENST0000049671417318_36560315.0DomainF-box

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHSY3chr5:129244053chr5:107684231ENST00000305031+23539_544362883.0Compositional biasNote=Poly-Leu
HgeneCHSY3chr5:129244053chr5:107684231ENST00000305031+2329_882362883.0Topological domainLumenal
TgeneFBXL17chr5:129244053chr5:107684231ENST000003596602925_2860304.0Compositional biasNote=Poly-Arg
TgeneFBXL17chr5:129244053chr5:107684231ENST000003596602929_8660304.0Compositional biasNote=Pro-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST000004967141725_2860315.0Compositional biasNote=Poly-Arg
TgeneFBXL17chr5:129244053chr5:107684231ENST000004967141729_8660315.0Compositional biasNote=Pro-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST0000054226729216_236458702.0Compositional biasNote=Gly-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST000005422672925_28458702.0Compositional biasNote=Poly-Arg
TgeneFBXL17chr5:129244053chr5:107684231ENST000005422672929_86458702.0Compositional biasNote=Pro-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST000005422672990_151458702.0Compositional biasNote=Ala-rich
TgeneFBXL17chr5:129244053chr5:107684231ENST0000054226729318_365458702.0DomainF-box


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Fusion Gene Sequence for CHSY3-FBXL17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16736_16736_1_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000359660_length(transcript)=4861nt_BP=1444nt
GGGTGGCAGCCTAGGAGCGGACGCGTTGCCGCCGCCGCTGCTCCTCCTCCTCCTCCTGCAGCTCCTCCAGCTGCCGCTGCTGCCGCCGCT
GCCGCCACCGCCGCCGCCGGGAGAAGTTTCACTCCCGACCCTTGCTCGGAGCCCCGGCCCAGAGCTGAGCGGGAGCCCGGCAGGCAGCTG
CAGCCCGCGGCAGTCGAGGCGTCCGCGGCGCTTCGACCTCCAGCCGGTGTCGGCGCCTAGGCGGCCGGCTGCGGCCGCGGCTGGGGGCGC
AAAGGCGGAGGAGGGGCGGGTGTGAGCCGGGGAAACCGCGTGCCGCGCCGCGACAGCCCAGCGAGCGTCCGCGCCCGGGACAGCCGCGAT
GGCTGTGCGCTCTCGCCGCCCGTGGATGAGCGTGGCATTAGGGCTGGTGCTGGGCTTCACCGCCGCGTCCTGGCTCATCGCCCCCAGGGT
GGCGGAGCTGAGCGAGAGGAAGAGACGTGGCTCCAGCCTCTGCTCCTACTACGGTCGCTCTGCTGCTGGCCCCCGCGCCGGCGCTCAGCA
GCCGCTCCCCCAGCCCCAGTCCCGACCACGGCAGGAGCAGTCGCCGCCCCCCGCGCGCCAGGATCTCCAGGGGCCACCGCTGCCCGAGGC
AGCACCCGGGATCACCAGTTTTCGAAGCAGCCCCTGGCAGCAGCCACCTCCGCTGCAGCAGCGGCGGCGAGGACGCGAGCCTGAGGGCGC
GACGGGGCTTCCCGGTGCTCCAGCGGCCGAGGGGGAGCCCGAGGAGGAGGACGGGGGCGCGGCTGGGCAGCGGAGAGACGGCCGGCCGGG
GAGTAGCCACAACGGCAGCGGGGACGGGGGCGCTGCCGCCCCGAGCGCCCGACCCCGGGACTTCCTGTACGTGGGGGTGATGACCGCGCA
GAAGTACCTGGGCAGCCGCGCGCTGGCCGCGCAGCGGACCTGGGCGCGTTTCATCCCGGGCCGCGTGGAGTTCTTTTCCAGCCAGCAGCC
CCCCAACGCCGGCCAGCCCCCGCCACCCCTGCCTGTCATCGCGCTACCGGGTGTGGACGACTCCTATCCTCCCCAGAAAAAGTCCTTCAT
GATGATCAAGTACATGCACGACCACTACCTGGACAAGTATGAGTGGTTCATGCGCGCCGACGACGATGTCTACATCAAAGGTGATAAATT
AGAAGAGTTTCTTAGATCGCTAAACAGCAGTAAGCCTCTCTACCTGGGACAGACTGGCCTGGGGAATATTGAAGAGCTTGGAAAGCTGGG
ACTGGAGCCTGGGGAAAACTTCTGTATGGGAGGACCTGGCATGATCTTTAGCCGAGAAGTTCTCAGGAGGATGGTGCCACATATTGGTGA
ATGCCTTAGAGAAATGTACACGACTCATGAGGATGTGGAAGTAGGAAGATGCGTTCGCCGTTTTGGTGGGACTCAGTGTGTCTGGTCTTA
CGAGCTGGGCTCAAAATGCAGAGAACTCAAAGATATTCATTTCGGCCAGTGTTACAAGATCTCAGATGAAGGCATGATCGTCATAGCTAA
GGGCTGTCTGAAATTACAAAGGATATACATGCAGGAAAACAAATTAGTGACAGATCAGTCAGTGAAAGCATTTGCTGAACACTGTCCTGA
GCTTCAATATGTAGGCTTCATGGGTTGTTCAGTCACTTCTAAAGGAGTCATTCACCTAACCAAGCTAAGAAACCTTTCCAGCTTGGACCT
ACGTCATATCACTGAACTGGATAATGAAACCGTGATGGAAATTGTCAAGAGGTGCAAAAATCTTAGCTCTCTCAATCTCTGTCTGAACTG
GATCATAAATGACAGGTGTGTGGAGGTCATTGCAAAGGAAGGACAAAACCTGAAAGAGCTATATTTGGTGTCCTGTAAAATCACAGATTA
TGCACTGATAGCCATTGGGCGATACAGCATGACAATAGAGACTGTGGATGTCGGATGGTGTAAAGAAATCACAGACCAAGGAGCCACCCT
GATTGCACAGAGCAGCAAGTCTCTGAGATATTTGGGGCTGATGAGATGTGATAAAGTCAACGAAGTGACGGTGGAACAGCTGGTGCAGCA
GTACCCCCACATCACCTTCAGCACCGTCCTGCAGGACTGCAAGAGGACCTTGGAGAGAGCCTATCAGATGGGCTGGACCCCCAACATGTC
TGCCGCCTCCTCCTAGCGCTCCTGCCTCGCCTAGTCCACTGGGATCATTCAGCAGAGCAGAGGAGAATTGTACATTTGGGGAGCTGATCT
CTCGGAAGGGTTTTAACTGTCACCTGTCTGTGTGTGTTCAAGTATGTGTATTTGTGTCTTGTTTGCATACTGCATACCAAAAGTGCAGTT
GTCATTTGTTCCCAAGTGAGCTGGCTTTTTTTCTTAGAAATTAAAGATTATGAAAGCCACAAACTTTTTAGTTTTTAACTTCAAAGGCTT
CTTTCTCTTTAAAAAAAAATTATTTTTAATATAGAGTCAAAAAATTGGATGTATTATTTTGAGCTTCTAATTGCTGCCACTTGGAGATGT
CCAAGTAAGAAGGCCTTCTTTTTACATGGGATGAATTGTGCACTTCTACTGATGATGACTACAGCAGAAGTGATGTTATACGTACAGGCA
CTTACACTCTCTCACATATTCACACGTGTGCACATCTACACCAGGGCTCTGATCTACTCTAGATCGTTTCCTGACAGAGAAGCCTTCTTC
CAGGCCACTAAGGTAGCATGTTATCCACTGTGGCACTGCCTAACTCCGTGTATCCTCGGGTGGCCAACTTGCTATCTGGTGGGTGACTTG
GGGACTAGAAAGAATAAAGCCTTTTCTAAATTTGTTATATAGAGGCAACAGTCTGAACTCTCCTGGCCAGCTCACGAAAGTTAATTATAC
ATTATTCTACAAATGCATTCTGTTGAGCACTAAATATTTTAGTTGGTTTTATGTTAACATTGTGTTAGCTTTTATTTCCTGGATAGTAAC
TGGTCAGGATATATTTTAATGATATTTGAAACTAATCTTAGCATTGAAGCCACCAATGTAATTAATGGTGTGCAGTTATTTTAAAAACTA
CAGATCATTTCATTATTTTCTTAATTTTGGTAATTATTAAAGTCTATTTCTGAGATACGAGAGGGTAGTCACATTAATAGAAGATTCATG
AGTGAGATATAAGTAGACAATCTTTCTACTGTTGTTGCTCTTTTTGCTTTGCTTTGGGTTCTTGAACAGGTTTTTTGGATATATGCATGT
TGTCATTTTGGACTAGTTCTCATGCTACTGCAAAGATCTATTGCTAGCTAATATATGAGTTAAGAAAGAAAATTAGAAAATCTGTTCATT
GAAATTCTGTTTACACTTGTCAGAAATAAGCATTTCTTTGTTTAATTAAGGATTGCCAGCTTCAGTTAAGACAAGACCTATCAGTAAATG
AATATATGTTTTGATTTAACACATCTTTACAATTAATTCATAATAGGGACTCAGGCTCAAATAACTGTTCCTGTGTCTAGATTTATAATG
AGGACATCAGGGAGCCTTTTTAAGCTAAAGAGTGATTATCTTTCACAGTAGAACTAGAAACAAAACCCTAACTTGTGAAGTTGCTATTTA
TTTTTCCCTGAGTGAATATAACTGTTATTTGGTCTTTAACAGATATACTGAGGTTTGAGTTTCACTTTCTTTAAGTCTCACATTGCTAAC
ATGACATTAGCTGTAAGAAACAAGATAGCTTTACATTTGAATGCCATTTACTGATTTCTAATGATTCTCTTTTTTTGTAAACAACTGTTT
CCTTTGATTATGTCAACATGTTTCTGATGTGGCATTTTTGTTTTAATCCCAATCGGTTAGGAAAATCTAGTCAGTAAGCGCCATGAGTAT
TCTTCCCATAACTAAATGGGTTTCTAATTTAATTTGAAGGGAATAAAATTTGTGTAAGAAAAAAGCTGTTTAACATTAATAAACTATATT
TCTTCTTACACATTGAACTGTATCATTTTCATATCCACTTCCCCACCACTGAAATATCTTATTTCACAATATTTTAACTGATTTTTAATC
CAAAACTAATTTATAAGACAGTATGTATAGTAATAGTAGCTTGAGTGAATATGCAAAAGTTTAATTTTTATATATGTCATACTATATTTT
AAATAGTTAAAAAAGACAAAAGAAGGGAGAGCCATCTATGATATAGATGGTACCATTTCAGTTCAAAGTTGTAATAACCTTTGGAGTGTT
ACAGTTTGGTTGTCAAATGGTTTCAGAATGTATAATTGATTTTTTTAAATGTTGCATTGTTTGAATCTAAAGTACAGCACTATAACATGC
TTTAGCTTGGGGGGGTGGGGGTGGGGTGGGGACTTGCACTTATTCTCTAAAATGTTGACTAATCCAGAAAGCCTGATGCAACATAATCTG
GAAAACTGCTTTGGTACATTTGTAGAAATCCGTAGAAATACCATATCCAGCCTCAAAGCATTAATCTCAAAAAAAAAAAAAAAAAAAAAA
AAAAACAGCCAGAAAAAAGCATCACCTTGAGTGGTCCTGTGATGGTTGTTGAATGTGTTCTCATTAGATGCTTTGAAATGAGGCTTAAAA
TAATTTTTCTGGGCAATATAGAGTTTCTTTTTTTTGCTTAGAATGTCATAAATACATGTGAACACGTTTAATGCAGGGCTTTTTATTCTC
TCCAAAATGTCAACAGTATTTTCAGAATAAAGACTATGAAATATATTGCTGTAGTGGAAAATTCTGGTCCTTTGTCTTTAATGTCTTTTT
GAGTGGATAAAGAAAATTCACCCGGTTTGTAGTTTCTATATTTCCGTGAATCTTTGACCTTGCAGTGGGTTGCAATAAAAGAGAAACAAA

>16736_16736_1_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000359660_length(amino acids)=605AA_BP=362
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPE
AAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTA
QKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDK
LEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWS
YELGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLD
LRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGAT

--------------------------------------------------------------
>16736_16736_2_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000496714_length(transcript)=4835nt_BP=1444nt
GGGTGGCAGCCTAGGAGCGGACGCGTTGCCGCCGCCGCTGCTCCTCCTCCTCCTCCTGCAGCTCCTCCAGCTGCCGCTGCTGCCGCCGCT
GCCGCCACCGCCGCCGCCGGGAGAAGTTTCACTCCCGACCCTTGCTCGGAGCCCCGGCCCAGAGCTGAGCGGGAGCCCGGCAGGCAGCTG
CAGCCCGCGGCAGTCGAGGCGTCCGCGGCGCTTCGACCTCCAGCCGGTGTCGGCGCCTAGGCGGCCGGCTGCGGCCGCGGCTGGGGGCGC
AAAGGCGGAGGAGGGGCGGGTGTGAGCCGGGGAAACCGCGTGCCGCGCCGCGACAGCCCAGCGAGCGTCCGCGCCCGGGACAGCCGCGAT
GGCTGTGCGCTCTCGCCGCCCGTGGATGAGCGTGGCATTAGGGCTGGTGCTGGGCTTCACCGCCGCGTCCTGGCTCATCGCCCCCAGGGT
GGCGGAGCTGAGCGAGAGGAAGAGACGTGGCTCCAGCCTCTGCTCCTACTACGGTCGCTCTGCTGCTGGCCCCCGCGCCGGCGCTCAGCA
GCCGCTCCCCCAGCCCCAGTCCCGACCACGGCAGGAGCAGTCGCCGCCCCCCGCGCGCCAGGATCTCCAGGGGCCACCGCTGCCCGAGGC
AGCACCCGGGATCACCAGTTTTCGAAGCAGCCCCTGGCAGCAGCCACCTCCGCTGCAGCAGCGGCGGCGAGGACGCGAGCCTGAGGGCGC
GACGGGGCTTCCCGGTGCTCCAGCGGCCGAGGGGGAGCCCGAGGAGGAGGACGGGGGCGCGGCTGGGCAGCGGAGAGACGGCCGGCCGGG
GAGTAGCCACAACGGCAGCGGGGACGGGGGCGCTGCCGCCCCGAGCGCCCGACCCCGGGACTTCCTGTACGTGGGGGTGATGACCGCGCA
GAAGTACCTGGGCAGCCGCGCGCTGGCCGCGCAGCGGACCTGGGCGCGTTTCATCCCGGGCCGCGTGGAGTTCTTTTCCAGCCAGCAGCC
CCCCAACGCCGGCCAGCCCCCGCCACCCCTGCCTGTCATCGCGCTACCGGGTGTGGACGACTCCTATCCTCCCCAGAAAAAGTCCTTCAT
GATGATCAAGTACATGCACGACCACTACCTGGACAAGTATGAGTGGTTCATGCGCGCCGACGACGATGTCTACATCAAAGGTGATAAATT
AGAAGAGTTTCTTAGATCGCTAAACAGCAGTAAGCCTCTCTACCTGGGACAGACTGGCCTGGGGAATATTGAAGAGCTTGGAAAGCTGGG
ACTGGAGCCTGGGGAAAACTTCTGTATGGGAGGACCTGGCATGATCTTTAGCCGAGAAGTTCTCAGGAGGATGGTGCCACATATTGGTGA
ATGCCTTAGAGAAATGTACACGACTCATGAGGATGTGGAAGTAGGAAGATGCGTTCGCCGTTTTGGTGGGACTCAGTGTGTCTGGTCTTA
CGAGCTGGGCTCAAAATGCAGAGAACTCAAAGATATTCATTTCGGCCAGTGTTACAAGATCTCAGATGAAGGCATGATCGTCATAGCTAA
GGGCTGTCTGAAATTACAAAGGATATACATGCAGGAAAACAAATTAGTGACAGATCAGTCAGTGAAAGCATTTGCTGAACACTGTCCTGA
GCTTCAATATGTAGGCTTCATGGGTTGTTCAGTCACTTCTAAAGGAGTCATTCACCTAACCAAGCTAAGAAACCTTTCCAGCTTGGACCT
ACGTCATATCACTGAACTGGATAATGAAACCGTGATGGAAATTGTCAAGAGGTGCAAAAATCTTAGCTCTCTCAATCTCTGTCTGAACTG
GATCATAAATGACAGGTGTGTGGAGGTCATTGCAAAGGAAGGACAAAACCTGAAAGAGCTATATTTGGTGTCCTGTAAAATCACAGATTA
TGCACTGATAGCCATTGGGCGATACAGCATGACAATAGAGACTGTGGATGTCGGATGGTGTAAAGAAATCACAGACCAAGGAGCCACCCT
GATTGCACAGAGCAGCAAGTCTCTGAGATATTTGGGGCTGATGAGATGTGATAAAGTAAGAGTTGACTATCAAGTTGTTTGCTTTCTACA
TATCAGTATAGTTAATAGCTTGATGTCATATCCTCTCTCCTTCTCTATCTCCACCCCCGTGTATTATATATTATATATACATTTTATATG
TATATATGCAATTATAGCTATGCATTGTTTGCCTGCTTTTGTAAACTAATCTGAGATTATCTTTGTATTTCCCCACTTAATAATGAATTT
TGTGCTTAAGTAGAAAGAAAAAGTAATCATATACATAGTCAACTAGAGTTTGGCATCCTATTCATAAGTCCATGGACCAAAATGTAAAAG
ATTACATGACAAACTGCAATTTGCAGGGTCTAACCGTAAAATTGTATTCTGGGTTTCAAGTTTCCAGCAACAGTAAAGGTGGAAAGAACA
GTGCCAAATTGGTTTTTCACAAGTGTGTAATTTTGGTACTGAACATCTATGTATTCTGGCCATTCGGGACCAACAAAGGGCCAGTAAGGG
GGTATGTGGGAATTTGCATCTCCCCATACATCAGATGCCACTCCCAGCACATGATAAGAAGTGGTTCCAGAGGTCCTGGTGGAAGGCCTG
TAGAACCAGCCAGGGATGTGAGCATGAGTTTAGGAAATGGTGTAGCATTTAACGTGGGACCCTTTGAAGACTGAGAAAACAGATAATAAA
AATCTATACTGACACCTGTAATCCCAGCACATTGGGAGGCCAAGGCAGAAGGATCACTTGAGCCCAGGAATTTGAGACCAGCCTGGACAA
CATGGGAAAACCCTGTCTCTATCCCCCTCTCCCCCAACAAAAAAAAATTAGCCAGGCATAATGGCACACACCTGTAGTCCCAGCTACTCG
GGAAGCTAAGGTGGGAGGATCACCTGAGCTCAAGAGGCCGAGGTTGCAGTGAGCCGTGATTGTGCCGCAACCACCTCAGCCTGGATGACG
GAGCACGACTGTGTCCCAAACAAACAAAAAAAACCTATACTGGACACCAGGCACTCCACAGGTGTTTTCTTCTTTGTTTATTCCATGTTT
TACCTATAACAAGTCTAAGAAATAGTTATTTGCATTGTGAAGGGGAGAAAATGGAGGCTCAGAAAGACCAGTCAGTGGCCCCAGGATACT
CTGGCAAGACTTCATGCCGGGTCTTTGGAGTCTGTATCCAGTGCTGCTGGCACAACCCAGGGGGCAGTCTGTGGCCACGGGGACTGCTTC
CCTTGGAAAAGGTCCAGTTCAGATACTTGCTCAGAAAGTGCCGCCATCTTGTACTAATTTACACATGTGTGCTACTTTTGTAAATGGTGA
TTAGGAACAAATCTAGCAAAATAATGTGAAACTAAATAGACACGCCATTCAAAGGGCATGCATCTTCTAAATGTAGCAAATGTGGGGGCA
AATGAAGTATGGCCCAAAGCTCTTGTGTCCTTTGTGATTTTTTGTTAATTGGCTAATTCTTTTCTCCAAACACTTTAGAATCCCAACTTA
TACGAGACCTTTGCCAGCTAGTTATGTTTAGAGAAATGTTATTATATATTCTCAGCCCAGCCCAGAAGCGACTTACTTTGTAACTAAGCA
ACAGCACTGAGATCCGGGGCTTGCGAGTCTCCCACAAATCTTTCCACTAACCAACCTAATGCCGCTGCTAACCCTGCCACTTTAAAATGA
CTTCTTTTAAGACAAGTTAAAGGGTCCACCATAGGCATAGTCCTCTAGAAACAGGAATCAATGACAGCAGAACTCCTCAGCTTCCAGCAG
AAGGAACTGCCACATGAATGCTAACTAAAGCTACCAAAATGTACACATTCATACATATGTGTCCGCAGCCATTCTCAGAAATTGTCATAT
TTCTAACCTGTAATCTTTAGATGGTTAAGATCAGCTCCATCTTCGGAGATACACTGTAGAAGTTGTATGTTACAGTTACTACAGGAGAAT
GTTATTCCAGACATATTTGCTGACCAGCATTTTGCTGATTTTTAGTTAAGAAATGGGTTATTTTCTACCCAAATGCAAATTAGTCCAAAA
TTAAATAGAGACAGTATTCAGATTAGCTGTATCCCTGAGGGTTTTAGCCCTTTTCCTGGGCTGCCTCTGAATCCTTTCTCTAACCAGAGA
GCCACTCTGAGAACCCATTGGCTCCAGCACGACGCCGTCTGGTCAGAGCCTGCTGCAGTGCAGCCCAGGGAGATGCTGGACCCAGCCTTG
CTGTCTGGCTTCCTCAGACTTAAAGCAGCTCAGAGCCAAACACGAGAGGCTCTGTGAGGATGGAAGACAGTTCCAAACCACACACAAAGC
ACAAGTAAAGCCTTGCACAGAAAAGCCTGCTTGTTGGTTTAGTTGGATGGAAATCTAAAGTAGCTATTCAGTTTTCAGATTTTGTATCAT
GCCATCCATCTCCAGATTTTAAGTTACCATCAAGATTCAAAGGAAGATATGAGTAACAAAGAAAAGAAATTAGTAGCAACGGTATGGTCT
GCGGAGAGCCAGAGTTCAGGTTCAGATCTGGGCTTTGCACTTACTAGTTGTGTCACCGCGGGCAGTTACTAACCTCTCAGTGCCTGTTCC
CTCGTTTGCAAAATGAGGATGATACTAGTACCTATCTTGTAGAATTGTGAGCATGTGAATGAGTTAACATACATAAAGCACTTAGAATAA
TGTCTATTATATATAAAATGCTCTGTTACTGATTAGTCTTATCATCCATATCATTATATTAACCTGTGTTGTGATACTGGAATTTTCCAA

>16736_16736_2_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000496714_length(amino acids)=616AA_BP=362
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPE
AAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTA
QKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDK
LEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWS
YELGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLD
LRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGAT

--------------------------------------------------------------
>16736_16736_3_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000542267_length(transcript)=4851nt_BP=1444nt
GGGTGGCAGCCTAGGAGCGGACGCGTTGCCGCCGCCGCTGCTCCTCCTCCTCCTCCTGCAGCTCCTCCAGCTGCCGCTGCTGCCGCCGCT
GCCGCCACCGCCGCCGCCGGGAGAAGTTTCACTCCCGACCCTTGCTCGGAGCCCCGGCCCAGAGCTGAGCGGGAGCCCGGCAGGCAGCTG
CAGCCCGCGGCAGTCGAGGCGTCCGCGGCGCTTCGACCTCCAGCCGGTGTCGGCGCCTAGGCGGCCGGCTGCGGCCGCGGCTGGGGGCGC
AAAGGCGGAGGAGGGGCGGGTGTGAGCCGGGGAAACCGCGTGCCGCGCCGCGACAGCCCAGCGAGCGTCCGCGCCCGGGACAGCCGCGAT
GGCTGTGCGCTCTCGCCGCCCGTGGATGAGCGTGGCATTAGGGCTGGTGCTGGGCTTCACCGCCGCGTCCTGGCTCATCGCCCCCAGGGT
GGCGGAGCTGAGCGAGAGGAAGAGACGTGGCTCCAGCCTCTGCTCCTACTACGGTCGCTCTGCTGCTGGCCCCCGCGCCGGCGCTCAGCA
GCCGCTCCCCCAGCCCCAGTCCCGACCACGGCAGGAGCAGTCGCCGCCCCCCGCGCGCCAGGATCTCCAGGGGCCACCGCTGCCCGAGGC
AGCACCCGGGATCACCAGTTTTCGAAGCAGCCCCTGGCAGCAGCCACCTCCGCTGCAGCAGCGGCGGCGAGGACGCGAGCCTGAGGGCGC
GACGGGGCTTCCCGGTGCTCCAGCGGCCGAGGGGGAGCCCGAGGAGGAGGACGGGGGCGCGGCTGGGCAGCGGAGAGACGGCCGGCCGGG
GAGTAGCCACAACGGCAGCGGGGACGGGGGCGCTGCCGCCCCGAGCGCCCGACCCCGGGACTTCCTGTACGTGGGGGTGATGACCGCGCA
GAAGTACCTGGGCAGCCGCGCGCTGGCCGCGCAGCGGACCTGGGCGCGTTTCATCCCGGGCCGCGTGGAGTTCTTTTCCAGCCAGCAGCC
CCCCAACGCCGGCCAGCCCCCGCCACCCCTGCCTGTCATCGCGCTACCGGGTGTGGACGACTCCTATCCTCCCCAGAAAAAGTCCTTCAT
GATGATCAAGTACATGCACGACCACTACCTGGACAAGTATGAGTGGTTCATGCGCGCCGACGACGATGTCTACATCAAAGGTGATAAATT
AGAAGAGTTTCTTAGATCGCTAAACAGCAGTAAGCCTCTCTACCTGGGACAGACTGGCCTGGGGAATATTGAAGAGCTTGGAAAGCTGGG
ACTGGAGCCTGGGGAAAACTTCTGTATGGGAGGACCTGGCATGATCTTTAGCCGAGAAGTTCTCAGGAGGATGGTGCCACATATTGGTGA
ATGCCTTAGAGAAATGTACACGACTCATGAGGATGTGGAAGTAGGAAGATGCGTTCGCCGTTTTGGTGGGACTCAGTGTGTCTGGTCTTA
CGAGCTGGGCTCAAAATGCAGAGAACTCAAAGATATTCATTTCGGCCAGTGTTACAAGATCTCAGATGAAGGCATGATCGTCATAGCTAA
GGGCTGTCTGAAATTACAAAGGATATACATGCAGGAAAACAAATTAGTGACAGATCAGTCAGTGAAAGCATTTGCTGAACACTGTCCTGA
GCTTCAATATGTAGGCTTCATGGGTTGTTCAGTCACTTCTAAAGGAGTCATTCACCTAACCAAGCTAAGAAACCTTTCCAGCTTGGACCT
ACGTCATATCACTGAACTGGATAATGAAACCGTGATGGAAATTGTCAAGAGGTGCAAAAATCTTAGCTCTCTCAATCTCTGTCTGAACTG
GATCATAAATGACAGGTGTGTGGAGGTCATTGCAAAGGAAGGACAAAACCTGAAAGAGCTATATTTGGTGTCCTGTAAAATCACAGATTA
TGCACTGATAGCCATTGGGCGATACAGCATGACAATAGAGACTGTGGATGTCGGATGGTGTAAAGAAATCACAGACCAAGGAGCCACCCT
GATTGCACAGAGCAGCAAGTCTCTGAGATATTTGGGGCTGATGAGATGTGATAAAGTCAACGAAGTGACGGTGGAACAGCTGGTGCAGCA
GTACCCCCACATCACCTTCAGCACCGTCCTGCAGGACTGCAAGAGGACCTTGGAGAGAGCCTATCAGATGGGCTGGACCCCCAACATGTC
TGCCGCCTCCTCCTAGCGCTCCTGCCTCGCCTAGTCCACTGGGATCATTCAGCAGAGCAGAGGAGAATTGTACATTTGGGGAGCTGATCT
CTCGGAAGGGTTTTAACTGTCACCTGTCTGTGTGTGTTCAAGTATGTGTATTTGTGTCTTGTTTGCATACTGCATACCAAAAGTGCAGTT
GTCATTTGTTCCCAAGTGAGCTGGCTTTTTTTCTTAGAAATTAAAGATTATGAAAGCCACAAACTTTTTAGTTTTTAACTTCAAAGGCTT
CTTTCTCTTTAAAAAAAAATTATTTTTAATATAGAGTCAAAAAATTGGATGTATTATTTTGAGCTTCTAATTGCTGCCACTTGGAGATGT
CCAAGTAAGAAGGCCTTCTTTTTACATGGGATGAATTGTGCACTTCTACTGATGATGACTACAGCAGAAGTGATGTTATACGTACAGGCA
CTTACACTCTCTCACATATTCACACGTGTGCACATCTACACCAGGGCTCTGATCTACTCTAGATCGTTTCCTGACAGAGAAGCCTTCTTC
CAGGCCACTAAGGTAGCATGTTATCCACTGTGGCACTGCCTAACTCCGTGTATCCTCGGGTGGCCAACTTGCTATCTGGTGGGTGACTTG
GGGACTAGAAAGAATAAAGCCTTTTCTAAATTTGTTATATAGAGGCAACAGTCTGAACTCTCCTGGCCAGCTCACGAAAGTTAATTATAC
ATTATTCTACAAATGCATTCTGTTGAGCACTAAATATTTTAGTTGGTTTTATGTTAACATTGTGTTAGCTTTTATTTCCTGGATAGTAAC
TGGTCAGGATATATTTTAATGATATTTGAAACTAATCTTAGCATTGAAGCCACCAATGTAATTAATGGTGTGCAGTTATTTTAAAAACTA
CAGATCATTTCATTATTTTCTTAATTTTGGTAATTATTAAAGTCTATTTCTGAGATACGAGAGGGTAGTCACATTAATAGAAGATTCATG
AGTGAGATATAAGTAGACAATCTTTCTACTGTTGTTGCTCTTTTTGCTTTGCTTTGGGTTCTTGAACAGGTTTTTTGGATATATGCATGT
TGTCATTTTGGACTAGTTCTCATGCTACTGCAAAGATCTATTGCTAGCTAATATATGAGTTAAGAAAGAAAATTAGAAAATCTGTTCATT
GAAATTCTGTTTACACTTGTCAGAAATAAGCATTTCTTTGTTTAATTAAGGATTGCCAGCTTCAGTTAAGACAAGACCTATCAGTAAATG
AATATATGTTTTGATTTAACACATCTTTACAATTAATTCATAATAGGGACTCAGGCTCAAATAACTGTTCCTGTGTCTAGATTTATAATG
AGGACATCAGGGAGCCTTTTTAAGCTAAAGAGTGATTATCTTTCACAGTAGAACTAGAAACAAAACCCTAACTTGTGAAGTTGCTATTTA
TTTTTCCCTGAGTGAATATAACTGTTATTTGGTCTTTAACAGATATACTGAGGTTTGAGTTTCACTTTCTTTAAGTCTCACATTGCTAAC
ATGACATTAGCTGTAAGAAACAAGATAGCTTTACATTTGAATGCCATTTACTGATTTCTAATGATTCTCTTTTTTTGTAAACAACTGTTT
CCTTTGATTATGTCAACATGTTTCTGATGTGGCATTTTTGTTTTAATCCCAATCGGTTAGGAAAATCTAGTCAGTAAGCGCCATGAGTAT
TCTTCCCATAACTAAATGGGTTTCTAATTTAATTTGAAGGGAATAAAATTTGTGTAAGAAAAAAGCTGTTTAACATTAATAAACTATATT
TCTTCTTACACATTGAACTGTATCATTTTCATATCCACTTCCCCACCACTGAAATATCTTATTTCACAATATTTTAACTGATTTTTAATC
CAAAACTAATTTATAAGACAGTATGTATAGTAATAGTAGCTTGAGTGAATATGCAAAAGTTTAATTTTTATATATGTCATACTATATTTT
AAATAGTTAAAAAAGACAAAAGAAGGGAGAGCCATCTATGATATAGATGGTACCATTTCAGTTCAAAGTTGTAATAACCTTTGGAGTGTT
ACAGTTTGGTTGTCAAATGGTTTCAGAATGTATAATTGATTTTTTTAAATGTTGCATTGTTTGAATCTAAAGTACAGCACTATAACATGC
TTTAGCTTGGGGGGGTGGGGGTGGGGTGGGGACTTGCACTTATTCTCTAAAATGTTGACTAATCCAGAAAGCCTGATGCAACATAATCTG
GAAAACTGCTTTGGTACATTTGTAGAAATCCGTAGAAATACCATATCCAGCCTCAAAGCATTAATCTCAAAAAAAAAAAAAAAAAAAAAA
AAAAACAGCCAGAAAAAAGCATCACCTTGAGTGGTCCTGTGATGGTTGTTGAATGTGTTCTCATTAGATGCTTTGAAATGAGGCTTAAAA
TAATTTTTCTGGGCAATATAGAGTTTCTTTTTTTTGCTTAGAATGTCATAAATACATGTGAACACGTTTAATGCAGGGCTTTTTATTCTC
TCCAAAATGTCAACAGTATTTTCAGAATAAAGACTATGAAATATATTGCTGTAGTGGAAAATTCTGGTCCTTTGTCTTTAATGTCTTTTT

>16736_16736_3_CHSY3-FBXL17_CHSY3_chr5_129244053_ENST00000305031_FBXL17_chr5_107684231_ENST00000542267_length(amino acids)=605AA_BP=362
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPE
AAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTA
QKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDK
LEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWS
YELGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLD
LRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGAT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CHSY3-FBXL17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CHSY3-FBXL17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CHSY3-FBXL17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource