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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CIRH1A-ZFPM1 (FusionGDB2 ID:16843)

Fusion Gene Summary for CIRH1A-ZFPM1

Fusion gene summary

Fusion gene information	Fusion gene name: CIRH1A-ZFPM1
	Fusion gene ID: 16843
		Hgene	Tgene
	Gene symbol	CIRH1A	ZFPM1
	Gene ID	84916	161882
	Gene name	UTP4 small subunit processome component	zinc finger protein, FOG family member 1
	Synonyms	CIRH1A\|CIRHIN\|NAIC\|TEX292	FOG\|FOG1\|ZC2HC11A\|ZNF408\|ZNF89A
	Cytomap	16q22.1	16q24.2
	Type of gene	protein-coding	protein-coding
	Description	U3 small nucleolar RNA-associated protein 4 homologUTP4 small subunit (SSU) processome componentUTP4, small subunit (SSU) processome component, homologcirrhosis, autosomal recessive 1A (cirhin)testis expressed gene 292	zinc finger protein ZFPM1FOG-1friend of GATA 1friend of GATA protein 1zinc finger protein 89Azinc finger protein, multitype 1
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000563094, ENST00000314423, ENST00000352319, ENST00000569615,	ENST00000319555, ENST00000569086,
Fusion gene scores	* DoF score	4 X 5 X 3=60	6 X 5 X 3=90
	# samples	5	6
	** MAII score	log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/90*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CIRH1A [Title/Abstract] AND ZFPM1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CIRH1A(69201088)-ZFPM1(88593221), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CIRH1A	GO:0006355	regulation of transcription, DNA-templated	19732766
Tgene	ZFPM1	GO:0010724	regulation of definitive erythrocyte differentiation	15920471
Tgene	ZFPM1	GO:0045078	positive regulation of interferon-gamma biosynthetic process	21646796
Tgene	ZFPM1	GO:0045403	negative regulation of interleukin-4 biosynthetic process	21646796

Fusion gene breakpoints across CIRH1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ZFPM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-BR-8588	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+

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Fusion Gene ORF analysis for CIRH1A-ZFPM1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000563094	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
3UTR-intron	ENST00000563094	ENST00000569086	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
5CDS-intron	ENST00000314423	ENST00000569086	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
5CDS-intron	ENST00000352319	ENST00000569086	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
In-frame	ENST00000314423	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
In-frame	ENST00000352319	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
intron-3CDS	ENST00000569615	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+
intron-intron	ENST00000569615	ENST00000569086	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000314423

CIRH1A

chr16

69201088

ENST00000319555

ZFPM1

chr16

88593221

6777

2121

4739

1561

ENST00000352319

CIRH1A

chr16

69201088

ENST00000319555

ZFPM1

chr16

88593221

6297

1641

4259

1405

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000314423	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+	0.004180356	0.99581957
ENST00000352319	ENST00000319555	CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+	0.003301543	0.99669844

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Fusion Genomic Features for CIRH1A-ZFPM1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+	0.001462965	0.99853706
CIRH1A	chr16	69201088	+	ZFPM1	chr16	88593221	+	0.001462965	0.99853706

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CIRH1A-ZFPM1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:69201088/chr16:88593221)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

136_181

648

687.0

Repeat

Note=WD 4

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

182_226

648

687.0

Repeat

Note=WD 5

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

227_275

648

687.0

Repeat

Note=WD 6

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

276_317

648

687.0

Repeat

Note=WD 7

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

318_377

648

687.0

Repeat

Note=WD 8

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

378_427

648

687.0

Repeat

Note=WD 9

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

428_475

648

687.0

Repeat

Note=WD 10

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

476_516

648

687.0

Repeat

Note=WD 11

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

517_566

648

687.0

Repeat

Note=WD 12

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

51_92

648

687.0

Repeat

Note=WD 2

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

567_627

648

687.0

Repeat

Note=WD 13

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

7_50

648

687.0

Repeat

Note=WD 1

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

93_135

648

687.0

Repeat

Note=WD 3

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

136_181

533

572.0

Repeat

Note=WD 4

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

182_226

533

572.0

Repeat

Note=WD 5

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

227_275

533

572.0

Repeat

Note=WD 6

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

276_317

533

572.0

Repeat

Note=WD 7

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

318_377

533

572.0

Repeat

Note=WD 8

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

378_427

533

572.0

Repeat

Note=WD 9

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

428_475

533

572.0

Repeat

Note=WD 10

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

476_516

533

572.0

Repeat

Note=WD 11

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

51_92

533

572.0

Repeat

Note=WD 2

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

7_50

533

572.0

Repeat

Note=WD 1

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

93_135

533

572.0

Repeat

Note=WD 3

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

235_268

134

1007.0

Zinc finger

CCHC FOG-type 1

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

290_314

134

1007.0

Zinc finger

C2H2-type 1

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

320_342

134

1007.0

Zinc finger

C2H2-type 2

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

348_371

134

1007.0

Zinc finger

C2H2-type 3

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

571_604

134

1007.0

Zinc finger

CCHC FOG-type 2

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

677_710

134

1007.0

Zinc finger

CCHC FOG-type 3

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

811_844

134

1007.0

Zinc finger

CCHC FOG-type 4

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

854_877

134

1007.0

Zinc finger

C2H2-type 4

Tgene

ZFPM1

chr16:69201088

chr16:88593221

ENST00000319555

968_1001

134

1007.0

Zinc finger

CCHC FOG-type 5

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000314423

628_666

648

687.0

Repeat

Note=WD 14

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

517_566

533

572.0

Repeat

Note=WD 12

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

567_627

533

572.0

Repeat

Note=WD 13

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000352319

628_666

533

572.0

Repeat

Note=WD 14

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

136_181

626.0

Repeat

Note=WD 4

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

182_226

626.0

Repeat

Note=WD 5

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

227_275

626.0

Repeat

Note=WD 6

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

276_317

626.0

Repeat

Note=WD 7

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

318_377

626.0

Repeat

Note=WD 8

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

378_427

626.0

Repeat

Note=WD 9

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

428_475

626.0

Repeat

Note=WD 10

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

476_516

626.0

Repeat

Note=WD 11

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

517_566

626.0

Repeat

Note=WD 12

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

51_92

626.0

Repeat

Note=WD 2

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

567_627

626.0

Repeat

Note=WD 13

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

628_666

626.0

Repeat

Note=WD 14

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

7_50

626.0

Repeat

Note=WD 1

Hgene

CIRH1A

chr16:69201088

chr16:88593221

ENST00000563094

93_135

626.0

Repeat

Note=WD 3

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Fusion Gene Sequence for CIRH1A-ZFPM1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>16843_16843_1_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000314423_ZFPM1_chr16_88593221_ENST00000319555_length(transcript)=6777nt_BP=2121nt
GCGGCCAACGGGCGACAACCGAACCTCCCGCCGCCGTCGCCGCCGCCGCGAGCACTGCCTGCGCACTTCCGACTATGCGCCAGGAGCACT
TCCGGGGCAGAGCCTGAGAGCGCGCGCGCACGTGGGGCCGGGGCGGAGAGAGGCGAGCACCGGGAAGGGGAGCGTGGGGCCGCTGGAATG
GGTGAATTTAAGGTCCATCGAGTACGTTTCTTTAATTATGTTCCATCAGGAATCCGCTGTGTGGCTTACAATAACCAGTCAAACAGATTG
GCTGTTTCACGAACAGATGGCACTGTGGAAATTTATAACTTGTCAGCAAACTACTTTCAGGAGAAATTTTTCCCAGGTCATGAGTCTCGG
GCTACAGAAGCTTTGTGCTGGGCAGAAGGACAGCGACTCTTTAGTGCTGGGCTCAATGGCGAGATTATGGAGTATGATTTACAGGCGTTA
AACATCAAGTATGCTATGGATGCCTTTGGAGGACCTATTTGGAGCATGGCTGCCAGCCCCAGTGGCTCTCAACTTTTGGTTGGTTGTGAA
GATGGATCTGTGAAACTATTTCAAATTACCCCAGACAAAATCCAGTTTGAAAGAAATTTTGATCGGCAGAAAAGTCGCATCCTGAGTCTC
AGCTGGCATCCCTCTGGTACCCACATTGCAGCTGGTTCCATAGACTACATTAGTGTGTTTGATGTCAAATCAGGCAGCGCTGTTCATAAG
ATGATTGTGGACAGGCAGTATATGGGCGTGTCTAAGCGGAAGTGCATCGTGTGGGGTGTCGCCTTCTTGTCCGATGGCACTATCATAAGT
GTGGACTCTGCTGGGAAGGTGCAGTTCTGGGACTCAGCCACTGGGACGCTTGTGAAGAGCCATCTCATCGCTAATGCTGACGTGCAGTCC
ATTGCTGTAGCTGACCAAGAAGACAGTTTCGTGGTGGGCACAGCCGAGGGAACAGTCTTCCATTTTCAGCTGGTCCCTGTGACATCTAAC
AGCAGTGAGAAGCAGTGGGTGCGGACAAAACCGTTCCAGCATCACACTCATGACGTGCGCACTGTGGCCCACAGCCCAACAGCGCTGATA
TCTGGAGGCACTGACACCCACTTAGTCTTTCGTCCTCTCATGGAGAAGGTGGAAGTAAAGAATTACGATGCCGCTCTCCGAAAAATCACC
TTTCCCCACCGATGTCTCATCTCCTGTTCTAAAAAGAGGCAGCTTCTCCTCTTCCAGTTTGCTCATCACTTAGAACTTTGGCGACTGGGA
TCCACAGTTGCAACAGGCAAGAATGGGGATACTCTTCCACTCTCTAAAAATGCAGATCATTTACTGCACCTAAAGACAAAGGGTCCTGAG
AACATTATCTGTAGCTGTATCTCCCCATGTGGAAGTTGGATAGCCTATTCTACAGTTTCTCGGTTTTTTCTCTATCGGCTGAATTATGAA
CATGACAACATAAGCCTCAAAAGGGTTTCCAAAATGCCAGCATTCCTTCGCTCTGCCCTTCAGATTTTGTTTTCTGAAGATTCAACAAAG
CTCTTTGTAGCATCAAATCAAGGAGCTCTGCATATTGTTCAGCTGTCAGGAGGAAGCTTCAAGCACCTGCATGCTTTCCAGCCTCAGTCA
GGAACAGTGGAGGCCATGTGTCTTTTGGCAGTCAGTCCAGATGGGAATTGGCTAGCTGCATCAGGTACCAGTGCTGGAGTCCATGTCTAC
AACGTAAAACAGCTAAAGCTTCACTGCACGGTGCCTGCTTACAATTTCCCAGTGACTGCTATGGCTATTGCCCCCAATACCAACAACCTT
GTCATCGCTCATTCGGACCAGCAGGTATTTGAGTACAGCATCCCAGACAAACAGTATACAGATTGGAGCCGGACTGTCCAGAAGCAGGGC
TTTCACCACCTTTGGCTCCAAAGGGATACTCCTATCACACACATCAGTTTTCATCCCAAGAGACCGATGCACATCCTTCTCCATGATGCC
TACATGTTCTGCATCATTGACAAGTCATTGCCCCTTCCAAATGACAAAACCTTACTCTACAATCCATTTCCTCCCACGAATGAATCAGAT
GTCATCCGGAGGCGCACAGCTCATGCTTTTAAAATTTCTAAGATATATAAGAGCCCAGCCCTGACCCTGCTGCTGGTGGACGAGGCCTGC
TGGCTGAGGACGCTGCCCCAGGCCCTGACTGAGGCCGAGGCCAACACAGAGATCCACAGGAAGGATGACGCACTCTGGTGCAGGGTCACC
AAGCCGGTGCCTGCGGGGGGACTCCTGAGCGTGCTCCTCACGGCCGAGCCCCACAGCACCCCCGGCCACCCTGTGAAGAAGGAGCCAGCA
GAGCCCACGTGCCCGGCCCCTGCACACGACCTCCAGCTCCTGCCCCAGCAGGCCGGGATGGCCTCCATCCTTGCCACCGCAGTGATCAAC
AAAGACGTCTTCCCCTGCAAGGACTGTGGCATCTGGTACCGCAGCGAGCGCAACCTGCAGGCGCACCTGCTCTACTACTGCGCCAGCCGC
CAGGGCACCGGCTCCCCGGCCGCAGCCGCCACAGACGAGAAGCCCAAAGAGACCTACCCCAACGAGCGCGTCTGCCCCTTCCCCCAGTGC
CGCAAGAGCTGCCCCAGCGCCAGCTCCCTGGAGATCCACATGCGCAGCCACAGCGGAGAGCGGCCCTTCGTGTGCCTGATCTGCCTGTCG
GCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTCAAGGTGCACACGGACACGCTGAGCGGTGTCTGCCACAGCTGTGGCTTCATCTCC
ACCACAAGGGACATCCTCTACAGCCACTTGGTCACCAACCACATGGTCTGCCAGCCTGGCTCCAAGGGTGAGATCTACTCGCCAGGGGCC
GGACACCCAGCAACCAAGCTGCCCCCAGACAGTCTGGGCAGCTTCCAGCAGCAGCACACGGCCCTGCAAGGCCCCCTGGCCTCCGCGGAC
CTGGGCCTGGCGCCCACCCCATCGCCAGGACTGGACAGAAAGGCCCTGGCCGAGGCCACCAACGGAGAGGCCAGAGCGGAGCCTCTGGCC
CAGAATGGAGGCAGCAGCGAGCCCCCGGCGGCCCCCAGGAGCATCAAGGTGGAGGCGGTGGAGGAGCCGGAGGCGGCCCCCATCCTGGGC
CCCGGAGAGCCTGGGCCCCAGGCCCCGTCGCGGACGCCGTCGCCGCGCAGCCCCGCCCCGGCCAGGGTCAAGGCCGAGCTGTCCAGCCCC
ACGCCGGGCTCCAGCCCGGTGCCCGGCGAGCTGGGCCTGGCCGGGGCCCTGTTCCTTCCGCAGTACGTGTTCGGGCCCGACGCGGCGCCC
CCCGCCTCGGAGATCCTGGCCAAGATGTCCGAGCTGGTGCACAGCCGGCTGCAGCAGGGCGCGGGCGCGGGCGCCGGCGGCGCGCAGACC
GGGCTCTTCCCCGGGGCCCCCAAGGGCGCTACGTGCTTCGAGTGCGAGATCACCTTCAGCAACGTCAACAACTACTACGTGCACAAGCGC
CTCTACTGTTCAGGCCGCCGTGCGCCCGAGGACGCGCCTGCCGCGCGCAGGCCCAAGGCGCCCCCCGGCCCGGCCCGCGCGCCCCCCGGC
CAGCCCGCCGAACCCGACGCGCCGCGCTCGTCCCCGGGCCCCGGAGCGCGCGAGGAGGGGGCTGGGGGCGCGGCCACGCCCGAGGACGGC
GCGGGCGGCCGGGGCAGCGAGGGCAGCCAGAGCCCGGGTAGCTCCGTGGACGACGCGGAGGACGACCCCAGCCGCACGCTGTGCGAGGCC
TGCAACATCCGCTTCAGCCGCCACGAGACCTACACCGTGCACAAGCGGTACTACTGCGCCTCGCGCCACGACCCGCCGCCGCGCCGACCG
GCCGCGCCCCCGGGACCCCCTGGGCCGGCCGCGCCCCCGGCCCCCTCTCCCGCCGCGCCTGTGCGCACGCGCAGACGCCGCAAGCTCTAC
GAGCTGCACGCGGCCGGCGCCCCGCCCCCCCCGCCGCCCGGCCACGCCCCCGCGCCCGAGTCGCCGCGGCCCGGAAGCGGAAGCGGAAGC
GGCCCCGGCCTCGCCCCTGCGCGCTCGCCCGGCCCCGCGGCCGACGGCCCCATCGACCTGAGCAAGAAGCCGCGGCGCCCGCTCCCCGGA
GCCCCGGCACCGGCGCTGGCCGACTACCACGAGTGCACGGCCTGCCGCGTGAGCTTCCACAGCCTCGAGGCCTACCTGGCGCACAAGAAG
TACTCGTGCCCCGCTGCGCCACCGCCCGGCGCGCTCGGCCTGCCCGCCGCCGCCTGCCCCTACTGCCCCCCGAACGGCCCGGTGCGCGGG
GACCTGCTGGAGCATTTCCGCCTGGCGCACGGCCTGCTGCTCGGCGCGCCCCTGGCCGGCCCGGGGGTCGAGGCCCGGACGCCGGCCGAC
CGCGGCCCCTCGCCCGCTCCCGCCCCCGCCGCCTCCCCGCAGCCCGGGTCCCGTGGCCCCCGGGACGGCCTCGGCCCGGAGCCCCAGGAG
CCGCCGCCCGGCCCGCCCCCGTCCCCGGCCGCCGCGCCCGAGGCCGTGCCGCCCCCGCCGGCGCCCCCCTCCTACTCGGACAAGGGCGTC
CAGACTCCCAGCAAGGGCACGCCGGCGCCGCTGCCCAACGGCAACCACCGGTACTGCCGTCTTTGCAACATCAAGTTCAGCAGCCTGTCC
ACCTTCATCGCCCACAAGAAGTATTACTGCTCCTCGCACGCCGCCGAGCACGTGAAGTGAGCGCCCACACTACAGCCGCAGACGCTTTGC
ACGCCCCGCTGCGATGCGGGGAGGGGGCCGCCCCCAGGCCGCACGGACTGCCGCTCCTGGGAACCCCGCCACGCACAGGCCTCGGCGGAG
GGGGCCGCAGGGGGCAGCGCCCGCCTGGACCCTTGGCACTTAATAAAGAAGTTCAGTTTGATGAGCATGGTGGTGGGCCAGCCTAGTTCT
CTGAGCCAGCAGGCACACGCAGCCAGTGTCACATCCAGCCCTGCTGTGTACACAGGCCACTGCGGCCCGGAGTGGCTGGGCCCCTGCCGG
AGTTACACCACTGGGTGCTAAGAGCTAGACCGAGCGTCAGGTCGGAGGCCACAGCACACACTGAACCACTGCAGGGCCAGCCGCTCTGGG
CCTACCCCACCCCAGCCCTGTCCATACCCCCCTAGGGAGAGCAGCCTCCACACTGCTGACCCTCTCCACGGTCTACTTGGCCGCCAGACA
CGGAAGAGAGGGGCACTGACCTGGCTGGCCATCCCCCAACCCTGCATGGTCCTGGGGGTCCGATGTCCCCCATCCAGTCACAGACCACCA
GGGATGGCAGGGGTGGGGGCGCCCTGGGGAGGATGAAGCCCTGTGGTGGCCAAGGCTGGGGGAAGAACAGGCGAGTAGGTGGACAGGAGA
GGGAGACCGAGGCCGAAGCATTCCCTGGCCTCGAGGGGGTCCTGATGCTCACTGGTGGGTGCATCTCTCCCTCAGAGCCAGGGCTGAGGA
CAACCGTGTGGTGGAGTCACCTGTGGTGGCTGAGTCGGTGCAAGGGTCAGGGCACCCCCACCCCCCGTCTTCCCTGCCCTGCTGGGCTGT
ATGGGCCGGCCACACTGAGGGAGTACTTGGCTGACCGCGTTCAGCCACGGTGTCACCGTGCCGTTTGCAGCTGGGTGGCTGTGGGCAGCC
TCCAGCGTGCTTTCTCACTGGAGAACAAAAACACTCTTCTATTCCCAACGTCACTTTATTTTTTTATTTTTGGGTCTCACTCTCTTGCCC
AGGCTGGAGTCCCTGGGATACTCACGGCTCATTGCAGCCTTGACCTCGTGAGCTCAAGTGATCTTCCCACCTCAGTTTCCTCAGTAGCTG
GGGCTACAGGTGTACACCACCATGCCCAGCTAGTTTTTGTGTTTTTTGTAGAAATGGTGTCTCCCTATGTTGCCCAGGCTGGGCAACCCT
ATATTTTTTAGAGCTAAGGTCTTGTTCGGTTCCCCAGGCTGAAGTTCAGTGGCACGATCATAAGTCACTGCAGCCTCAAACTCCTGAGCT
GAAACCATCTTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCTTGACCCACCACACCTGGCTAACTTTTAAAACATTTTTATAGA
GACAGGGTCTTCCTGTGTTGCCCAAGATGGTCTCAAACTCCTGACCTCCAGTGCTCCTGCAGCCTCAGCCTCCCAGAACATTAGGATGAC
AGGCGCGAGCTACCATTCCCAGCCCATTTCCAACTCTACTTGAACTAGCTGCATTTTTTTCAGCTTTGCCCAGCAGCCCTGGTGAGTGCA
GGCAAAGAAGGCAGCGGCCTCTTGCCTCAGAAGCCCGAGGCACTTCCCAGCCAGTCCAGGGCTCGCTCTCCTGCCCGCAGCTCGTGGGCC
TGGGTCTGCAGCGCTTTCAGTGGTCTCTGATGTCTTTGTCCACCTGCCCACTAGGGTCTGGCCAGATGGGGCCCGTAGCCAAGGCCAATG
GACAGACATGGCTTCCACCCCCTCCCAGGGACCTGAGCTCCAGGGAAGGCAAGCAGCCTTTTCCTCACAGACACCCCTTCTGTTGAAGAC
CAGGTGATAGCGGGGACGGGAGGCACGGACCCCTCAAGTCTGCTCATCATTTGCATTGTTGTGCATGAATTTGCGTGGAGGGTTCAGGAG
GCTCTGCCCCCAAGTCCTCCCCAGGTGCGGGCGCAGGGTACAAGATGTTCTAAAAAATAGAAACCTGGTGGGGGGTTGTCACTGTGTGTA

>16843_16843_1_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000314423_ZFPM1_chr16_88593221_ENST00000319555_length(amino acids)=1561AA_BP=1191
MPAHFRLCARSTSGAEPESARARGAGAERGEHREGERGAAGMGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANY
FQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFER
NFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLV
KSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVE
VKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYST
VSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWL
AASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFH
PKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKSPALTLLLVDEACWLRTLPQALTEAEANTEI
HRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERN
LQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDT
LSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE
ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALF
LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP
KAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYY
CASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPI
DLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPL
AGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHRY

--------------------------------------------------------------
>16843_16843_2_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000352319_ZFPM1_chr16_88593221_ENST00000319555_length(transcript)=6297nt_BP=1641nt
GAGAGAGGCGAGCACCGGGAAGGGGAGCGTGGGGCCGCTGGAATGGGTGAATTTAAGGTCCATCGAGTACGTTTCTTTAATTATGTTCCA
TCAGGAATCCGCTGTGTGGCTTACAATAACCAGTCAAACAGATTGGCTGTTTCACGAACAGATGGCACTGTGGAAATTTATAACTTGTCA
GCAAACTACTTTCAGGAGAAATTTTTCCCAGGTCATGAGTCTCGGGCTACAGAAGCTTTGTGCTGGGCAGAAGGACAGCGACTCTTTAGT
GCTGGGCTCAATGGCGAGATTATGGAGTATGATTTACAGGCGTTAAACATCAAGTATGCTATGGATGCCTTTGGAGGACCTATTTGGAGC
ATGGCTGCCAGCCCCAGTGGCTCTCAACTTTTGGTTGGTTGTGAAGATGGATCTGTGAAACTATTTCAAATTACCCCAGACAAAATCCAG
TTTGAAAGAAATTTTGATCGGCAGAAAAGTCGCATCCTGAGTCTCAGCTGGCATCCCTCTGGTACCCACATTGCAGCTGGTTCCATAGAC
TACATTAGTGTGTTTGATGTCAAATCAGGCAGCGCTGTTCATAAGATGATTGTGGACAGGCAGTATATGGGCGTGTCTAAGCGGAAGTGC
ATCGTGTGGGGTGTCGCCTTCTTGTCCGATGGCACTATCATAAGTGTGGACTCTGCTGGGAAGGTGCAGTTCTGGGACTCAGCCACTGGG
ACGCTTGTGAAGAGCCATCTCATCGCTAATGCTGACGTGCAGTCCATTGCTGTAGCTGACCAAGAAGACAGTTTCGTGGTGGGCACAGCC
GAGGGAACAGTCTTCCATTTTCAGCTGGTCCCTGTGACATCTAACAGCAGTGAGAAGCAGTGGGTGCGGACAAAACCGTTCCAGCATCAC
ACTCATGACGTGCGCACTGTGGCCCACAGCCCAACAGCGCTGATATCTGGAGGCACTGACACCCACTTAGTCTTTCGTCCTCTCATGGAG
AAGGTGGAAGTAAAGAATTACGATGCCGCTCTCCGAAAAATCACCTTTCCCCACCGATGTCTCATCTCCTGTTCTAAAAAGAGGCAGCTT
CTCCTCTTCCAGTTTGCTCATCACTTAGAACTTTGGCGACTGGGATCCACAGTTGCAACAGGAACAGTGGAGGCCATGTGTCTTTTGGCA
GTCAGTCCAGATGGGAATTGGCTAGCTGCATCAGGTACCAGTGCTGGAGTCCATGTCTACAACGTAAAACAGCTAAAGCTTCACTGCACG
GTGCCTGCTTACAATTTCCCAGTGACTGCTATGGCTATTGCCCCCAATACCAACAACCTTGTCATCGCTCATTCGGACCAGCAGGTATTT
GAGTACAGCATCCCAGACAAACAGTATACAGATTGGAGCCGGACTGTCCAGAAGCAGGGCTTTCACCACCTTTGGCTCCAAAGGGATACT
CCTATCACACACATCAGTTTTCATCCCAAGAGACCGATGCACATCCTTCTCCATGATGCCTACATGTTCTGCATCATTGACAAGTCATTG
CCCCTTCCAAATGACAAAACCTTACTCTACAATCCATTTCCTCCCACGAATGAATCAGATGTCATCCGGAGGCGCACAGCTCATGCTTTT
AAAATTTCTAAGATATATAAGAGCCCAGCCCTGACCCTGCTGCTGGTGGACGAGGCCTGCTGGCTGAGGACGCTGCCCCAGGCCCTGACT
GAGGCCGAGGCCAACACAGAGATCCACAGGAAGGATGACGCACTCTGGTGCAGGGTCACCAAGCCGGTGCCTGCGGGGGGACTCCTGAGC
GTGCTCCTCACGGCCGAGCCCCACAGCACCCCCGGCCACCCTGTGAAGAAGGAGCCAGCAGAGCCCACGTGCCCGGCCCCTGCACACGAC
CTCCAGCTCCTGCCCCAGCAGGCCGGGATGGCCTCCATCCTTGCCACCGCAGTGATCAACAAAGACGTCTTCCCCTGCAAGGACTGTGGC
ATCTGGTACCGCAGCGAGCGCAACCTGCAGGCGCACCTGCTCTACTACTGCGCCAGCCGCCAGGGCACCGGCTCCCCGGCCGCAGCCGCC
ACAGACGAGAAGCCCAAAGAGACCTACCCCAACGAGCGCGTCTGCCCCTTCCCCCAGTGCCGCAAGAGCTGCCCCAGCGCCAGCTCCCTG
GAGATCCACATGCGCAGCCACAGCGGAGAGCGGCCCTTCGTGTGCCTGATCTGCCTGTCGGCCTTCACCACCAAGGCCAACTGCGAGCGG
CACCTCAAGGTGCACACGGACACGCTGAGCGGTGTCTGCCACAGCTGTGGCTTCATCTCCACCACAAGGGACATCCTCTACAGCCACTTG
GTCACCAACCACATGGTCTGCCAGCCTGGCTCCAAGGGTGAGATCTACTCGCCAGGGGCCGGACACCCAGCAACCAAGCTGCCCCCAGAC
AGTCTGGGCAGCTTCCAGCAGCAGCACACGGCCCTGCAAGGCCCCCTGGCCTCCGCGGACCTGGGCCTGGCGCCCACCCCATCGCCAGGA
CTGGACAGAAAGGCCCTGGCCGAGGCCACCAACGGAGAGGCCAGAGCGGAGCCTCTGGCCCAGAATGGAGGCAGCAGCGAGCCCCCGGCG
GCCCCCAGGAGCATCAAGGTGGAGGCGGTGGAGGAGCCGGAGGCGGCCCCCATCCTGGGCCCCGGAGAGCCTGGGCCCCAGGCCCCGTCG
CGGACGCCGTCGCCGCGCAGCCCCGCCCCGGCCAGGGTCAAGGCCGAGCTGTCCAGCCCCACGCCGGGCTCCAGCCCGGTGCCCGGCGAG
CTGGGCCTGGCCGGGGCCCTGTTCCTTCCGCAGTACGTGTTCGGGCCCGACGCGGCGCCCCCCGCCTCGGAGATCCTGGCCAAGATGTCC
GAGCTGGTGCACAGCCGGCTGCAGCAGGGCGCGGGCGCGGGCGCCGGCGGCGCGCAGACCGGGCTCTTCCCCGGGGCCCCCAAGGGCGCT
ACGTGCTTCGAGTGCGAGATCACCTTCAGCAACGTCAACAACTACTACGTGCACAAGCGCCTCTACTGTTCAGGCCGCCGTGCGCCCGAG
GACGCGCCTGCCGCGCGCAGGCCCAAGGCGCCCCCCGGCCCGGCCCGCGCGCCCCCCGGCCAGCCCGCCGAACCCGACGCGCCGCGCTCG
TCCCCGGGCCCCGGAGCGCGCGAGGAGGGGGCTGGGGGCGCGGCCACGCCCGAGGACGGCGCGGGCGGCCGGGGCAGCGAGGGCAGCCAG
AGCCCGGGTAGCTCCGTGGACGACGCGGAGGACGACCCCAGCCGCACGCTGTGCGAGGCCTGCAACATCCGCTTCAGCCGCCACGAGACC
TACACCGTGCACAAGCGGTACTACTGCGCCTCGCGCCACGACCCGCCGCCGCGCCGACCGGCCGCGCCCCCGGGACCCCCTGGGCCGGCC
GCGCCCCCGGCCCCCTCTCCCGCCGCGCCTGTGCGCACGCGCAGACGCCGCAAGCTCTACGAGCTGCACGCGGCCGGCGCCCCGCCCCCC
CCGCCGCCCGGCCACGCCCCCGCGCCCGAGTCGCCGCGGCCCGGAAGCGGAAGCGGAAGCGGCCCCGGCCTCGCCCCTGCGCGCTCGCCC
GGCCCCGCGGCCGACGGCCCCATCGACCTGAGCAAGAAGCCGCGGCGCCCGCTCCCCGGAGCCCCGGCACCGGCGCTGGCCGACTACCAC
GAGTGCACGGCCTGCCGCGTGAGCTTCCACAGCCTCGAGGCCTACCTGGCGCACAAGAAGTACTCGTGCCCCGCTGCGCCACCGCCCGGC
GCGCTCGGCCTGCCCGCCGCCGCCTGCCCCTACTGCCCCCCGAACGGCCCGGTGCGCGGGGACCTGCTGGAGCATTTCCGCCTGGCGCAC
GGCCTGCTGCTCGGCGCGCCCCTGGCCGGCCCGGGGGTCGAGGCCCGGACGCCGGCCGACCGCGGCCCCTCGCCCGCTCCCGCCCCCGCC
GCCTCCCCGCAGCCCGGGTCCCGTGGCCCCCGGGACGGCCTCGGCCCGGAGCCCCAGGAGCCGCCGCCCGGCCCGCCCCCGTCCCCGGCC
GCCGCGCCCGAGGCCGTGCCGCCCCCGCCGGCGCCCCCCTCCTACTCGGACAAGGGCGTCCAGACTCCCAGCAAGGGCACGCCGGCGCCG
CTGCCCAACGGCAACCACCGGTACTGCCGTCTTTGCAACATCAAGTTCAGCAGCCTGTCCACCTTCATCGCCCACAAGAAGTATTACTGC
TCCTCGCACGCCGCCGAGCACGTGAAGTGAGCGCCCACACTACAGCCGCAGACGCTTTGCACGCCCCGCTGCGATGCGGGGAGGGGGCCG
CCCCCAGGCCGCACGGACTGCCGCTCCTGGGAACCCCGCCACGCACAGGCCTCGGCGGAGGGGGCCGCAGGGGGCAGCGCCCGCCTGGAC
CCTTGGCACTTAATAAAGAAGTTCAGTTTGATGAGCATGGTGGTGGGCCAGCCTAGTTCTCTGAGCCAGCAGGCACACGCAGCCAGTGTC
ACATCCAGCCCTGCTGTGTACACAGGCCACTGCGGCCCGGAGTGGCTGGGCCCCTGCCGGAGTTACACCACTGGGTGCTAAGAGCTAGAC
CGAGCGTCAGGTCGGAGGCCACAGCACACACTGAACCACTGCAGGGCCAGCCGCTCTGGGCCTACCCCACCCCAGCCCTGTCCATACCCC
CCTAGGGAGAGCAGCCTCCACACTGCTGACCCTCTCCACGGTCTACTTGGCCGCCAGACACGGAAGAGAGGGGCACTGACCTGGCTGGCC
ATCCCCCAACCCTGCATGGTCCTGGGGGTCCGATGTCCCCCATCCAGTCACAGACCACCAGGGATGGCAGGGGTGGGGGCGCCCTGGGGA
GGATGAAGCCCTGTGGTGGCCAAGGCTGGGGGAAGAACAGGCGAGTAGGTGGACAGGAGAGGGAGACCGAGGCCGAAGCATTCCCTGGCC
TCGAGGGGGTCCTGATGCTCACTGGTGGGTGCATCTCTCCCTCAGAGCCAGGGCTGAGGACAACCGTGTGGTGGAGTCACCTGTGGTGGC
TGAGTCGGTGCAAGGGTCAGGGCACCCCCACCCCCCGTCTTCCCTGCCCTGCTGGGCTGTATGGGCCGGCCACACTGAGGGAGTACTTGG
CTGACCGCGTTCAGCCACGGTGTCACCGTGCCGTTTGCAGCTGGGTGGCTGTGGGCAGCCTCCAGCGTGCTTTCTCACTGGAGAACAAAA
ACACTCTTCTATTCCCAACGTCACTTTATTTTTTTATTTTTGGGTCTCACTCTCTTGCCCAGGCTGGAGTCCCTGGGATACTCACGGCTC
ATTGCAGCCTTGACCTCGTGAGCTCAAGTGATCTTCCCACCTCAGTTTCCTCAGTAGCTGGGGCTACAGGTGTACACCACCATGCCCAGC
TAGTTTTTGTGTTTTTTGTAGAAATGGTGTCTCCCTATGTTGCCCAGGCTGGGCAACCCTATATTTTTTAGAGCTAAGGTCTTGTTCGGT
TCCCCAGGCTGAAGTTCAGTGGCACGATCATAAGTCACTGCAGCCTCAAACTCCTGAGCTGAAACCATCTTCCTGCCTCAGCCTCCCAAG
TAGCTGGGACTACAGGCTTGACCCACCACACCTGGCTAACTTTTAAAACATTTTTATAGAGACAGGGTCTTCCTGTGTTGCCCAAGATGG
TCTCAAACTCCTGACCTCCAGTGCTCCTGCAGCCTCAGCCTCCCAGAACATTAGGATGACAGGCGCGAGCTACCATTCCCAGCCCATTTC
CAACTCTACTTGAACTAGCTGCATTTTTTTCAGCTTTGCCCAGCAGCCCTGGTGAGTGCAGGCAAAGAAGGCAGCGGCCTCTTGCCTCAG
AAGCCCGAGGCACTTCCCAGCCAGTCCAGGGCTCGCTCTCCTGCCCGCAGCTCGTGGGCCTGGGTCTGCAGCGCTTTCAGTGGTCTCTGA
TGTCTTTGTCCACCTGCCCACTAGGGTCTGGCCAGATGGGGCCCGTAGCCAAGGCCAATGGACAGACATGGCTTCCACCCCCTCCCAGGG
ACCTGAGCTCCAGGGAAGGCAAGCAGCCTTTTCCTCACAGACACCCCTTCTGTTGAAGACCAGGTGATAGCGGGGACGGGAGGCACGGAC
CCCTCAAGTCTGCTCATCATTTGCATTGTTGTGCATGAATTTGCGTGGAGGGTTCAGGAGGCTCTGCCCCCAAGTCCTCCCCAGGTGCGG

>16843_16843_2_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000352319_ZFPM1_chr16_88593221_ENST00000319555_length(amino acids)=1405AA_BP=1035
MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQA
LNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVH
KMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTS
NSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRL
GSTVATGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSR
TVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKSPALTLL
LVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASIL
ATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFV
CLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQG
PLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVK
AELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNN
YYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPS
RTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRP
GSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPP
NGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CIRH1A-ZFPM1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	ZFPM1	chr16:69201088	chr16:88593221	ENST00000319555		3	10	794_800	134.0	1007.0	CTBP2
Tgene	ZFPM1	chr16:69201088	chr16:88593221	ENST00000319555		3	10	330_341	134.0	1007.0	TACC3

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CIRH1A-ZFPM1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CIRH1A-ZFPM1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source