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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CKAP5-SSB (FusionGDB2 ID:16896)

Fusion Gene Summary for CKAP5-SSB

check button Fusion gene summary
Fusion gene informationFusion gene name: CKAP5-SSB
Fusion gene ID: 16896
HgeneTgene
Gene symbol

CKAP5

SSB

Gene ID

9793

6741

Gene namecytoskeleton associated protein 5small RNA binding exonuclease protection factor La
SynonymsCHTOG|MSPS|TOG|TOGp|ch-TOGLARP3|La|La/SSB
Cytomap

11p11.2

2q31.1

Type of geneprotein-codingprotein-coding
Descriptioncytoskeleton-associated protein 5colonic and hepatic tumor over-expressed gene proteincolonic and hepatic tumor overexpressed gene proteinlupus La proteinLa ribonucleoprotein domain family, member 3SS-BSS-B/La proteinSjogren syndrome antigen Bautoantigen Lala autoantigenlupus La antigensjoegren syndrome type B antigen
Modification date2020031320200313
UniProtAcc

Q14008

P81877

Ensembl transtripts involved in fusion geneENST00000415402, ENST00000529230, 
ENST00000312055, ENST00000354558, 
ENST00000532321, 		ENST00000260956, 
ENST00000409333, 
Fusion gene scores* DoF score9 X 9 X 5=4059 X 12 X 7=756
# samples 915
** MAII scorelog2(9/405*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/756*10)=-2.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CKAP5 [Title/Abstract] AND SSB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCKAP5(46776438)-SSB(170663295), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCKAP5

GO:0090063

positive regulation of microtubule nucleation

26414402

TgeneSSB

GO:0075522

IRES-dependent viral translational initiation

12384597

TgeneSSB

GO:1903608

protein localization to cytoplasmic stress granule

24965446


check buttonFusion gene breakpoints across CKAP5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SSB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A04U-01ACKAP5chr11

46776438

-SSBchr2

170663295

+


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Fusion Gene ORF analysis for CKAP5-SSB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000415402ENST00000260956CKAP5chr11

46776438

-SSBchr2

170663295

+
In-frameENST00000415402ENST00000409333CKAP5chr11

46776438

-SSBchr2

170663295

+
In-frameENST00000529230ENST00000260956CKAP5chr11

46776438

-SSBchr2

170663295

+
In-frameENST00000529230ENST00000409333CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000312055ENST00000260956CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000312055ENST00000409333CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000354558ENST00000260956CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000354558ENST00000409333CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000532321ENST00000260956CKAP5chr11

46776438

-SSBchr2

170663295

+
intron-3CDSENST00000532321ENST00000409333CKAP5chr11

46776438

-SSBchr2

170663295

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000529230CKAP5chr1146776438-ENST00000260956SSBchr2170663295+610649164757971916
ENST00000529230CKAP5chr1146776438-ENST00000409333SSBchr2170663295+610649164757971916
ENST00000415402CKAP5chr1146776438-ENST00000260956SSBchr2170663295+6169497911058601916
ENST00000415402CKAP5chr1146776438-ENST00000409333SSBchr2170663295+6169497911058601916

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000529230ENST00000260956CKAP5chr1146776438-SSBchr2170663295+0.0007385080.99926144
ENST00000529230ENST00000409333CKAP5chr1146776438-SSBchr2170663295+0.0007385080.99926144
ENST00000415402ENST00000260956CKAP5chr1146776438-SSBchr2170663295+0.0007721190.9992279
ENST00000415402ENST00000409333CKAP5chr1146776438-SSBchr2170663295+0.0007721190.9992279

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Fusion Genomic Features for CKAP5-SSB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CKAP5chr1146776437-SSBchr2170663294+6.20E-080.9999999
CKAP5chr1146776437-SSBchr2170663294+6.20E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CKAP5-SSB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:46776438/chr2:170663295)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CKAP5

Q14008

SSB

P81877

FUNCTION: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448). {ECO:0000269|PubMed:12569123, ECO:0000269|PubMed:18809577, ECO:0000269|PubMed:21297582, ECO:0000269|PubMed:21646404, ECO:0000269|PubMed:23532825, ECO:0000269|PubMed:27156448, ECO:0000269|PubMed:9570755}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441193_142816232040.0RegionTOG 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441_22316232040.0RegionTOG 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644268_50216232040.0RegionTOG 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644588_81716232040.0RegionTOG 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644853_108116232040.0RegionTOG 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441193_142816232033.0RegionTOG 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441_22316232033.0RegionTOG 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644268_50216232033.0RegionTOG 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644588_81716232033.0RegionTOG 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644853_108116232033.0RegionTOG 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441013_105116232040.0RepeatNote=HEAT 7
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441284_132216232040.0RepeatNote=HEAT 8
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441324_135716232040.0RepeatNote=HEAT 9
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441361_139916232040.0RepeatNote=HEAT 10
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644159_19716232040.0RepeatNote=HEAT 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644356_39416232040.0RepeatNote=HEAT 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644434_47216232040.0RepeatNote=HEAT 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644750_78816232040.0RepeatNote=HEAT 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644855_89316232040.0RepeatNote=HEAT 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-3644936_97416232040.0RepeatNote=HEAT 6
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441013_105116232033.0RepeatNote=HEAT 7
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441284_132216232033.0RepeatNote=HEAT 8
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441324_135716232033.0RepeatNote=HEAT 9
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441361_139916232033.0RepeatNote=HEAT 10
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644159_19716232033.0RepeatNote=HEAT 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644356_39416232033.0RepeatNote=HEAT 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644434_47216232033.0RepeatNote=HEAT 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644750_78816232033.0RepeatNote=HEAT 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644855_89316232033.0RepeatNote=HEAT 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-3644936_97416232033.0RepeatNote=HEAT 6
TgeneSSBchr11:46776438chr2:170663295ENST00000260956312227_348115409.0DomainxRRM
TgeneSSBchr11:46776438chr2:170663295ENST00000409333312227_348115409.0DomainxRRM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431193_142801973.0RegionTOG 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431_22301973.0RegionTOG 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143268_50201973.0RegionTOG 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143588_81701973.0RegionTOG 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143853_108101973.0RegionTOG 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421193_142801973.0RegionTOG 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421_22301973.0RegionTOG 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142268_50201973.0RegionTOG 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142588_81701973.0RegionTOG 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142853_108101973.0RegionTOG 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431013_105101973.0RepeatNote=HEAT 7
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431284_132201973.0RepeatNote=HEAT 8
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431324_135701973.0RepeatNote=HEAT 9
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431361_139901973.0RepeatNote=HEAT 10
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143159_19701973.0RepeatNote=HEAT 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143356_39401973.0RepeatNote=HEAT 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143434_47201973.0RepeatNote=HEAT 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143750_78801973.0RepeatNote=HEAT 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143855_89301973.0RepeatNote=HEAT 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-143936_97401973.0RepeatNote=HEAT 6
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421013_105101973.0RepeatNote=HEAT 7
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421284_132201973.0RepeatNote=HEAT 8
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421324_135701973.0RepeatNote=HEAT 9
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421361_139901973.0RepeatNote=HEAT 10
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142159_19701973.0RepeatNote=HEAT 1
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142356_39401973.0RepeatNote=HEAT 2
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142434_47201973.0RepeatNote=HEAT 3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142750_78801973.0RepeatNote=HEAT 4
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142855_89301973.0RepeatNote=HEAT 5
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-142936_97401973.0RepeatNote=HEAT 6
TgeneSSBchr11:46776438chr2:170663295ENST00000260956312111_187115409.0DomainRRM
TgeneSSBchr11:46776438chr2:170663295ENST000002609563127_99115409.0DomainHTH La-type RNA-binding
TgeneSSBchr11:46776438chr2:170663295ENST00000409333312111_187115409.0DomainRRM
TgeneSSBchr11:46776438chr2:170663295ENST000004093333127_99115409.0DomainHTH La-type RNA-binding


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Fusion Gene Sequence for CKAP5-SSB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16896_16896_1_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000415402_SSB_chr2_170663295_ENST00000260956_length(transcript)=6169nt_BP=4979nt
ACTGCGGGGTGTGCGGCGGCCCAAGCGGTTTCAAACGGCTTAGAGCAGGCCGCTTGGTTCTGACCCAGCTGAGGAAATACTCTTAATTCT
AAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAA
GGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCA
AAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAA
AAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTC
TTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCT
GTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTG
AGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTAC
AAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTT
CCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCAC
AAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGC
AAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCAT
TAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGA
AATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGG
CAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGC
AGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCAC
TACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAG
CAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGA
AAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGG
ACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAG
GAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAG
AAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCC
AGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTA
ATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAG
ATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCAT
GGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAA
AAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTG
CTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCC
AGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATG
AAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAG
AGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTA
TCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCC
TGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCA
AGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTT
CTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGCTTCTGGGCTGGCTGGCTGAGAAACTACCTACTCTTCGTTCCACCCCTA
CAGACCTTATCCTTTGTGTTCCTCATCTCTACTCCTGCCTAGAAGATCGAAATGGAGATGTGCGAAAGAAGGCCCAAGATGCCTTGCCAT
TCTTCATGATGCATTTAGGATATGAAAAAATGGCCAAGGCTACTGGGAAACTAAAGCCAACTTCTAAAGATCAGGTATTGGCCATGCTAG
AGAAAGCCAAAGTTAACATGCCAGCCAAGCCTGCTCCACCCACTAAAGCAACTTCTAAACCAATGGGAGGGTCCGCTCCAGCCAAATTCC
AGCCTGCATCAGCACCTGCTGAAGATTGTATTTCCAGCAGTACAGAACCCAAACCTGATCCAAAAAAGGCCAAAGCTCCAGGATTATCCT
CTAAAGCAAAGAGTGCACAAGGGAAGAAGATGCCAAGCAAAACCAGCTTAAAGGAGGATGAAGACAAATCCGGGCCTATTTTTATTGTTG
TTCCAAATGGAAAAGAGCAAAGGATGAAAGATGAAAAAGGATTGAAGGTGCTAAAGTGGAATTTTACTACCCCACGGGATGAATACATTG
AGCAACTAAAGACTCAAATGTCTAGCTGTGTGGCTAAATGGTTACAAGATGAGATGTTTCACTCAGACTTTCAGCATCATAACAAAGCCC
TTGCTGTTATGGTTGATCACTTGGAGAGTGAAAAAGAAGGAGTTATTGGTTGCCTGGATCTTATCTTAAAGTGGCTTACCCTGAGGTTTT
TTGACACCAATACAAGCGTCCTGATGAAAGCACTAGAATATTTAAAATTGCTCTTCACCTTGCTAAGTGAAGAAGAATATCATCTTACTG
AGAATGAAGCATCTTCCTTCATCCCCTATCTTGTCGTCAAGGTTGGAGAACCAAAGGATGTCATTCGTAAAGATGTTCGTGCCATCCTGA
ACCGGATGTGCCTTGTCTACCCAGCTAGCAAGATGTTTCCCTTTATCATGGAAGGAACCAAATCCAAAAACTCTAAGCAGAGAGCAGAGT
GCCTGGAAGAGCTGGGATGTCTGGTTGAGTCCTATGGCATGAATGTTTGCCAACCAACCCCAGGAAAAGCCTTAAAGGAAATAGCTGTTC
ACATAGGAGACCGTGACAATGCTGTACGCAATGCTGCACTCAACACCATTGTAACGGTGTACAATGTACATGGGGATCAGGTGTTCAAAC
TGATTGGAAATCTTTCTGAAAAGGATATGAGCATGCTCGAGGAGAGGATTAAGCGGTCAGCAAAGAGACCCTCTGCTGCACCAATAAAAC
AGGTGGAAGAGAAACCTCAGCGTGCACAGAACATAAGCTCCAATGCCAACATGTTACGCAAGGGACCAGCTGAGGACATGTCTTCCAAAC
TCAACCAAGCCCGAAGCATGAGTGGGCATCCTGAGGCAGCCCAGATGGTCCGCCGAGAATTCCAGCTGGATCTAGATGAGATTGAGAATG
ACAATGGTACAGTCCGATGTGAAATGCCAGAACTTGTTCAGCACAAACTGGATGACATTTTTGAGCCAGTCCTTATTCCTGAACCCAAGA
TCCGGGCTGTTTCTCCACACTTCGATGACATGCACAGTAATACAGCATCCACAATCAATTTCATTATCTCCCAAGTAGCCAGTGGTGACA
TCAACACAAGTATCCAAGCTCTGACACAGATCGATGAGGTCCTGAGACAGGAAGACAAAGCTGAAGCCATGTCCGGCCATATTGATCAGT
TTCTGATAGCCACTTTTATGCAGCTAAGACTCATCTACAACACACACATGGCAGATGAGAAATTGGAGAAGGACGAGATCATCAAGTTGT
ATAGCTGTATCATTGGCAACATGATTTCGAAAGGCTTCCCAACTGATGCAACTCTTGATGACATAAAAGAATGGTTAGAAGATAAAGGTC
AAGTACTAAATATTCAGATGAGAAGAACATTGCATAAAGCATTTAAGGGATCAATTTTTGTTGTGTTTGATAGCATTGAATCTGCTAAGA
AATTTGTAGAGACCCCTGGCCAGAAGTACAAAGAAACAGACCTGCTAATACTTTTCAAGGACGATTACTTTGCCAAAAAAAATGAAGAAA
GAAAACAAAATAAAGTGGAAGCTAAATTAAGAGCTAAACAGGAGCAAGAAGCAAAACAAAAGTTAGAAGAAGATGCTGAAATGAAATCTC
TAGAAGAAAAGATTGGATGCTTGCTGAAATTTTCGGGTGATTTAGATGATCAGACCTGTAGAGAAGATTTACACATACTTTTCTCAAATC
ATGGTGAAATAAAATGGATAGACTTCGTCAGAGGAGCAAAAGAGGGGATAATTCTATTTAAAGAAAAAGCCAAGGAAGCATTGGGTAAAG
CCAAAGATGCAAATAATGGTAACCTACAATTAAGGAACAAAGAAGTGACTTGGGAAGTACTAGAAGGAGAGGTGGAAAAAGAAGCACTGA
AGAAAATAATAGAAGACCAACAAGAATCCCTAAACAAATGGAAGTCAAAAGGTCGTAGATTTAAAGGAAAAGGAAAGGGTAATAAAGCTG
CCCAGCCTGGGTCTGGTAAAGGAAAAGTACAGTTTCAGGGCAAGAAAACGAAATTTGCTAGTGATGATGAACATGATGAACATGATGAAA
ATGGTGCAACTGGACCTGTGAAAAGAGCAAGAGAAGAAACAGACAAAGAAGAACCTGCATCCAAACAACAGAAAACAGAAAATGGTGCTG
GAGACCAGTAGTTTAGTAAACCAATTTTTTATTCATTTTAAATAGGTTTTAAACGACTTTTGTTTGCGGGGCTTTTAAAAGGAAAACCGA
ATTAGGTCCACTTCAATGTCCACCTGTGAGAAAGGAAAAATTTTTTTGTTGTTTAACTTGTCTTTTTGTTATGCAAATGAGATTTCTTTG
AATGTATTGTTCTGTTTGTGTTATTTCAGATGATTCAAATATCAAAAGGAAGATTCTTCCATTAAATTGCCTTTGTAATATGAGAATGTA

>16896_16896_1_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000415402_SSB_chr2_170663295_ENST00000260956_length(amino acids)=1916AA_BP=1623
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ
RMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLEELGC
LVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRCEMPELVQHKLDDIFEPVLIPEPKIRAVSPH
FDDMHSNTASTINFIISQVASGDINTSIQALTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGN
MISKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVE
AKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG
NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV

--------------------------------------------------------------
>16896_16896_2_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000415402_SSB_chr2_170663295_ENST00000409333_length(transcript)=6169nt_BP=4979nt
ACTGCGGGGTGTGCGGCGGCCCAAGCGGTTTCAAACGGCTTAGAGCAGGCCGCTTGGTTCTGACCCAGCTGAGGAAATACTCTTAATTCT
AAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAA
GGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCA
AAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAA
AAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTC
TTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCT
GTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTG
AGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTAC
AAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTT
CCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCAC
AAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGC
AAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCAT
TAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGA
AATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGG
CAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGC
AGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCAC
TACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAG
CAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGA
AAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGG
ACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAG
GAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAG
AAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCC
AGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTA
ATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAG
ATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCAT
GGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAA
AAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTG
CTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCC
AGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATG
AAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAG
AGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTA
TCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCC
TGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCA
AGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTT
CTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGCTTCTGGGCTGGCTGGCTGAGAAACTACCTACTCTTCGTTCCACCCCTA
CAGACCTTATCCTTTGTGTTCCTCATCTCTACTCCTGCCTAGAAGATCGAAATGGAGATGTGCGAAAGAAGGCCCAAGATGCCTTGCCAT
TCTTCATGATGCATTTAGGATATGAAAAAATGGCCAAGGCTACTGGGAAACTAAAGCCAACTTCTAAAGATCAGGTATTGGCCATGCTAG
AGAAAGCCAAAGTTAACATGCCAGCCAAGCCTGCTCCACCCACTAAAGCAACTTCTAAACCAATGGGAGGGTCCGCTCCAGCCAAATTCC
AGCCTGCATCAGCACCTGCTGAAGATTGTATTTCCAGCAGTACAGAACCCAAACCTGATCCAAAAAAGGCCAAAGCTCCAGGATTATCCT
CTAAAGCAAAGAGTGCACAAGGGAAGAAGATGCCAAGCAAAACCAGCTTAAAGGAGGATGAAGACAAATCCGGGCCTATTTTTATTGTTG
TTCCAAATGGAAAAGAGCAAAGGATGAAAGATGAAAAAGGATTGAAGGTGCTAAAGTGGAATTTTACTACCCCACGGGATGAATACATTG
AGCAACTAAAGACTCAAATGTCTAGCTGTGTGGCTAAATGGTTACAAGATGAGATGTTTCACTCAGACTTTCAGCATCATAACAAAGCCC
TTGCTGTTATGGTTGATCACTTGGAGAGTGAAAAAGAAGGAGTTATTGGTTGCCTGGATCTTATCTTAAAGTGGCTTACCCTGAGGTTTT
TTGACACCAATACAAGCGTCCTGATGAAAGCACTAGAATATTTAAAATTGCTCTTCACCTTGCTAAGTGAAGAAGAATATCATCTTACTG
AGAATGAAGCATCTTCCTTCATCCCCTATCTTGTCGTCAAGGTTGGAGAACCAAAGGATGTCATTCGTAAAGATGTTCGTGCCATCCTGA
ACCGGATGTGCCTTGTCTACCCAGCTAGCAAGATGTTTCCCTTTATCATGGAAGGAACCAAATCCAAAAACTCTAAGCAGAGAGCAGAGT
GCCTGGAAGAGCTGGGATGTCTGGTTGAGTCCTATGGCATGAATGTTTGCCAACCAACCCCAGGAAAAGCCTTAAAGGAAATAGCTGTTC
ACATAGGAGACCGTGACAATGCTGTACGCAATGCTGCACTCAACACCATTGTAACGGTGTACAATGTACATGGGGATCAGGTGTTCAAAC
TGATTGGAAATCTTTCTGAAAAGGATATGAGCATGCTCGAGGAGAGGATTAAGCGGTCAGCAAAGAGACCCTCTGCTGCACCAATAAAAC
AGGTGGAAGAGAAACCTCAGCGTGCACAGAACATAAGCTCCAATGCCAACATGTTACGCAAGGGACCAGCTGAGGACATGTCTTCCAAAC
TCAACCAAGCCCGAAGCATGAGTGGGCATCCTGAGGCAGCCCAGATGGTCCGCCGAGAATTCCAGCTGGATCTAGATGAGATTGAGAATG
ACAATGGTACAGTCCGATGTGAAATGCCAGAACTTGTTCAGCACAAACTGGATGACATTTTTGAGCCAGTCCTTATTCCTGAACCCAAGA
TCCGGGCTGTTTCTCCACACTTCGATGACATGCACAGTAATACAGCATCCACAATCAATTTCATTATCTCCCAAGTAGCCAGTGGTGACA
TCAACACAAGTATCCAAGCTCTGACACAGATCGATGAGGTCCTGAGACAGGAAGACAAAGCTGAAGCCATGTCCGGCCATATTGATCAGT
TTCTGATAGCCACTTTTATGCAGCTAAGACTCATCTACAACACACACATGGCAGATGAGAAATTGGAGAAGGACGAGATCATCAAGTTGT
ATAGCTGTATCATTGGCAACATGATTTCGAAAGGCTTCCCAACTGATGCAACTCTTGATGACATAAAAGAATGGTTAGAAGATAAAGGTC
AAGTACTAAATATTCAGATGAGAAGAACATTGCATAAAGCATTTAAGGGATCAATTTTTGTTGTGTTTGATAGCATTGAATCTGCTAAGA
AATTTGTAGAGACCCCTGGCCAGAAGTACAAAGAAACAGACCTGCTAATACTTTTCAAGGACGATTACTTTGCCAAAAAAAATGAAGAAA
GAAAACAAAATAAAGTGGAAGCTAAATTAAGAGCTAAACAGGAGCAAGAAGCAAAACAAAAGTTAGAAGAAGATGCTGAAATGAAATCTC
TAGAAGAAAAGATTGGATGCTTGCTGAAATTTTCGGGTGATTTAGATGATCAGACCTGTAGAGAAGATTTACACATACTTTTCTCAAATC
ATGGTGAAATAAAATGGATAGACTTCGTCAGAGGAGCAAAAGAGGGGATAATTCTATTTAAAGAAAAAGCCAAGGAAGCATTGGGTAAAG
CCAAAGATGCAAATAATGGTAACCTACAATTAAGGAACAAAGAAGTGACTTGGGAAGTACTAGAAGGAGAGGTGGAAAAAGAAGCACTGA
AGAAAATAATAGAAGACCAACAAGAATCCCTAAACAAATGGAAGTCAAAAGGTCGTAGATTTAAAGGAAAAGGAAAGGGTAATAAAGCTG
CCCAGCCTGGGTCTGGTAAAGGAAAAGTACAGTTTCAGGGCAAGAAAACGAAATTTGCTAGTGATGATGAACATGATGAACATGATGAAA
ATGGTGCAACTGGACCTGTGAAAAGAGCAAGAGAAGAAACAGACAAAGAAGAACCTGCATCCAAACAACAGAAAACAGAAAATGGTGCTG
GAGACCAGTAGTTTAGTAAACCAATTTTTTATTCATTTTAAATAGGTTTTAAACGACTTTTGTTTGCGGGGCTTTTAAAAGGAAAACCGA
ATTAGGTCCACTTCAATGTCCACCTGTGAGAAAGGAAAAATTTTTTTGTTGTTTAACTTGTCTTTTTGTTATGCAAATGAGATTTCTTTG
AATGTATTGTTCTGTTTGTGTTATTTCAGATGATTCAAATATCAAAAGGAAGATTCTTCCATTAAATTGCCTTTGTAATATGAGAATGTA

>16896_16896_2_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000415402_SSB_chr2_170663295_ENST00000409333_length(amino acids)=1916AA_BP=1623
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ
RMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLEELGC
LVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRCEMPELVQHKLDDIFEPVLIPEPKIRAVSPH
FDDMHSNTASTINFIISQVASGDINTSIQALTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGN
MISKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVE
AKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG
NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV

--------------------------------------------------------------
>16896_16896_3_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000529230_SSB_chr2_170663295_ENST00000260956_length(transcript)=6106nt_BP=4916nt
CCCAGCTGAGGAAATACTCTTAATTCTAAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGA
AATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAG
AGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTT
ATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAG
CCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACA
ATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAA
TTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGA
TTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTG
CTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAG
GTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTT
ATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTG
GCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTA
CTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAAC
CTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAA
TGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGA
GCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTA
CTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAG
AAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAG
GGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCAC
CAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGC
CTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAG
AAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAG
CCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTT
CCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAG
CAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAA
CTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTG
CTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTG
AGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTT
CCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGA
CGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGG
CAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAA
TCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCC
CTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGA
AGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGCTTCTGGGCTGGCTGGCTGAGA
AACTACCTACTCTTCGTTCCACCCCTACAGACCTTATCCTTTGTGTTCCTCATCTCTACTCCTGCCTAGAAGATCGAAATGGAGATGTGC
GAAAGAAGGCCCAAGATGCCTTGCCATTCTTCATGATGCATTTAGGATATGAAAAAATGGCCAAGGCTACTGGGAAACTAAAGCCAACTT
CTAAAGATCAGGTATTGGCCATGCTAGAGAAAGCCAAAGTTAACATGCCAGCCAAGCCTGCTCCACCCACTAAAGCAACTTCTAAACCAA
TGGGAGGGTCCGCTCCAGCCAAATTCCAGCCTGCATCAGCACCTGCTGAAGATTGTATTTCCAGCAGTACAGAACCCAAACCTGATCCAA
AAAAGGCCAAAGCTCCAGGATTATCCTCTAAAGCAAAGAGTGCACAAGGGAAGAAGATGCCAAGCAAAACCAGCTTAAAGGAGGATGAAG
ACAAATCCGGGCCTATTTTTATTGTTGTTCCAAATGGAAAAGAGCAAAGGATGAAAGATGAAAAAGGATTGAAGGTGCTAAAGTGGAATT
TTACTACCCCACGGGATGAATACATTGAGCAACTAAAGACTCAAATGTCTAGCTGTGTGGCTAAATGGTTACAAGATGAGATGTTTCACT
CAGACTTTCAGCATCATAACAAAGCCCTTGCTGTTATGGTTGATCACTTGGAGAGTGAAAAAGAAGGAGTTATTGGTTGCCTGGATCTTA
TCTTAAAGTGGCTTACCCTGAGGTTTTTTGACACCAATACAAGCGTCCTGATGAAAGCACTAGAATATTTAAAATTGCTCTTCACCTTGC
TAAGTGAAGAAGAATATCATCTTACTGAGAATGAAGCATCTTCCTTCATCCCCTATCTTGTCGTCAAGGTTGGAGAACCAAAGGATGTCA
TTCGTAAAGATGTTCGTGCCATCCTGAACCGGATGTGCCTTGTCTACCCAGCTAGCAAGATGTTTCCCTTTATCATGGAAGGAACCAAAT
CCAAAAACTCTAAGCAGAGAGCAGAGTGCCTGGAAGAGCTGGGATGTCTGGTTGAGTCCTATGGCATGAATGTTTGCCAACCAACCCCAG
GAAAAGCCTTAAAGGAAATAGCTGTTCACATAGGAGACCGTGACAATGCTGTACGCAATGCTGCACTCAACACCATTGTAACGGTGTACA
ATGTACATGGGGATCAGGTGTTCAAACTGATTGGAAATCTTTCTGAAAAGGATATGAGCATGCTCGAGGAGAGGATTAAGCGGTCAGCAA
AGAGACCCTCTGCTGCACCAATAAAACAGGTGGAAGAGAAACCTCAGCGTGCACAGAACATAAGCTCCAATGCCAACATGTTACGCAAGG
GACCAGCTGAGGACATGTCTTCCAAACTCAACCAAGCCCGAAGCATGAGTGGGCATCCTGAGGCAGCCCAGATGGTCCGCCGAGAATTCC
AGCTGGATCTAGATGAGATTGAGAATGACAATGGTACAGTCCGATGTGAAATGCCAGAACTTGTTCAGCACAAACTGGATGACATTTTTG
AGCCAGTCCTTATTCCTGAACCCAAGATCCGGGCTGTTTCTCCACACTTCGATGACATGCACAGTAATACAGCATCCACAATCAATTTCA
TTATCTCCCAAGTAGCCAGTGGTGACATCAACACAAGTATCCAAGCTCTGACACAGATCGATGAGGTCCTGAGACAGGAAGACAAAGCTG
AAGCCATGTCCGGCCATATTGATCAGTTTCTGATAGCCACTTTTATGCAGCTAAGACTCATCTACAACACACACATGGCAGATGAGAAAT
TGGAGAAGGACGAGATCATCAAGTTGTATAGCTGTATCATTGGCAACATGATTTCGAAAGGCTTCCCAACTGATGCAACTCTTGATGACA
TAAAAGAATGGTTAGAAGATAAAGGTCAAGTACTAAATATTCAGATGAGAAGAACATTGCATAAAGCATTTAAGGGATCAATTTTTGTTG
TGTTTGATAGCATTGAATCTGCTAAGAAATTTGTAGAGACCCCTGGCCAGAAGTACAAAGAAACAGACCTGCTAATACTTTTCAAGGACG
ATTACTTTGCCAAAAAAAATGAAGAAAGAAAACAAAATAAAGTGGAAGCTAAATTAAGAGCTAAACAGGAGCAAGAAGCAAAACAAAAGT
TAGAAGAAGATGCTGAAATGAAATCTCTAGAAGAAAAGATTGGATGCTTGCTGAAATTTTCGGGTGATTTAGATGATCAGACCTGTAGAG
AAGATTTACACATACTTTTCTCAAATCATGGTGAAATAAAATGGATAGACTTCGTCAGAGGAGCAAAAGAGGGGATAATTCTATTTAAAG
AAAAAGCCAAGGAAGCATTGGGTAAAGCCAAAGATGCAAATAATGGTAACCTACAATTAAGGAACAAAGAAGTGACTTGGGAAGTACTAG
AAGGAGAGGTGGAAAAAGAAGCACTGAAGAAAATAATAGAAGACCAACAAGAATCCCTAAACAAATGGAAGTCAAAAGGTCGTAGATTTA
AAGGAAAAGGAAAGGGTAATAAAGCTGCCCAGCCTGGGTCTGGTAAAGGAAAAGTACAGTTTCAGGGCAAGAAAACGAAATTTGCTAGTG
ATGATGAACATGATGAACATGATGAAAATGGTGCAACTGGACCTGTGAAAAGAGCAAGAGAAGAAACAGACAAAGAAGAACCTGCATCCA
AACAACAGAAAACAGAAAATGGTGCTGGAGACCAGTAGTTTAGTAAACCAATTTTTTATTCATTTTAAATAGGTTTTAAACGACTTTTGT
TTGCGGGGCTTTTAAAAGGAAAACCGAATTAGGTCCACTTCAATGTCCACCTGTGAGAAAGGAAAAATTTTTTTGTTGTTTAACTTGTCT
TTTTGTTATGCAAATGAGATTTCTTTGAATGTATTGTTCTGTTTGTGTTATTTCAGATGATTCAAATATCAAAAGGAAGATTCTTCCATT

>16896_16896_3_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000529230_SSB_chr2_170663295_ENST00000260956_length(amino acids)=1916AA_BP=1623
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ
RMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLEELGC
LVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRCEMPELVQHKLDDIFEPVLIPEPKIRAVSPH
FDDMHSNTASTINFIISQVASGDINTSIQALTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGN
MISKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVE
AKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG
NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV

--------------------------------------------------------------
>16896_16896_4_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000529230_SSB_chr2_170663295_ENST00000409333_length(transcript)=6106nt_BP=4916nt
CCCAGCTGAGGAAATACTCTTAATTCTAAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGA
AATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAG
AGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTT
ATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAG
CCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACA
ATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAA
TTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGA
TTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTG
CTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAG
GTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTT
ATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTG
GCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTA
CTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAAC
CTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAA
TGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGA
GCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTA
CTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAG
AAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAG
GGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCAC
CAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGC
CTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAG
AAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAG
CCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTT
CCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAG
CAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAA
CTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTG
CTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTG
AGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTT
CCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGA
CGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGG
CAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAA
TCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCC
CTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGA
AGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGCTTCTGGGCTGGCTGGCTGAGA
AACTACCTACTCTTCGTTCCACCCCTACAGACCTTATCCTTTGTGTTCCTCATCTCTACTCCTGCCTAGAAGATCGAAATGGAGATGTGC
GAAAGAAGGCCCAAGATGCCTTGCCATTCTTCATGATGCATTTAGGATATGAAAAAATGGCCAAGGCTACTGGGAAACTAAAGCCAACTT
CTAAAGATCAGGTATTGGCCATGCTAGAGAAAGCCAAAGTTAACATGCCAGCCAAGCCTGCTCCACCCACTAAAGCAACTTCTAAACCAA
TGGGAGGGTCCGCTCCAGCCAAATTCCAGCCTGCATCAGCACCTGCTGAAGATTGTATTTCCAGCAGTACAGAACCCAAACCTGATCCAA
AAAAGGCCAAAGCTCCAGGATTATCCTCTAAAGCAAAGAGTGCACAAGGGAAGAAGATGCCAAGCAAAACCAGCTTAAAGGAGGATGAAG
ACAAATCCGGGCCTATTTTTATTGTTGTTCCAAATGGAAAAGAGCAAAGGATGAAAGATGAAAAAGGATTGAAGGTGCTAAAGTGGAATT
TTACTACCCCACGGGATGAATACATTGAGCAACTAAAGACTCAAATGTCTAGCTGTGTGGCTAAATGGTTACAAGATGAGATGTTTCACT
CAGACTTTCAGCATCATAACAAAGCCCTTGCTGTTATGGTTGATCACTTGGAGAGTGAAAAAGAAGGAGTTATTGGTTGCCTGGATCTTA
TCTTAAAGTGGCTTACCCTGAGGTTTTTTGACACCAATACAAGCGTCCTGATGAAAGCACTAGAATATTTAAAATTGCTCTTCACCTTGC
TAAGTGAAGAAGAATATCATCTTACTGAGAATGAAGCATCTTCCTTCATCCCCTATCTTGTCGTCAAGGTTGGAGAACCAAAGGATGTCA
TTCGTAAAGATGTTCGTGCCATCCTGAACCGGATGTGCCTTGTCTACCCAGCTAGCAAGATGTTTCCCTTTATCATGGAAGGAACCAAAT
CCAAAAACTCTAAGCAGAGAGCAGAGTGCCTGGAAGAGCTGGGATGTCTGGTTGAGTCCTATGGCATGAATGTTTGCCAACCAACCCCAG
GAAAAGCCTTAAAGGAAATAGCTGTTCACATAGGAGACCGTGACAATGCTGTACGCAATGCTGCACTCAACACCATTGTAACGGTGTACA
ATGTACATGGGGATCAGGTGTTCAAACTGATTGGAAATCTTTCTGAAAAGGATATGAGCATGCTCGAGGAGAGGATTAAGCGGTCAGCAA
AGAGACCCTCTGCTGCACCAATAAAACAGGTGGAAGAGAAACCTCAGCGTGCACAGAACATAAGCTCCAATGCCAACATGTTACGCAAGG
GACCAGCTGAGGACATGTCTTCCAAACTCAACCAAGCCCGAAGCATGAGTGGGCATCCTGAGGCAGCCCAGATGGTCCGCCGAGAATTCC
AGCTGGATCTAGATGAGATTGAGAATGACAATGGTACAGTCCGATGTGAAATGCCAGAACTTGTTCAGCACAAACTGGATGACATTTTTG
AGCCAGTCCTTATTCCTGAACCCAAGATCCGGGCTGTTTCTCCACACTTCGATGACATGCACAGTAATACAGCATCCACAATCAATTTCA
TTATCTCCCAAGTAGCCAGTGGTGACATCAACACAAGTATCCAAGCTCTGACACAGATCGATGAGGTCCTGAGACAGGAAGACAAAGCTG
AAGCCATGTCCGGCCATATTGATCAGTTTCTGATAGCCACTTTTATGCAGCTAAGACTCATCTACAACACACACATGGCAGATGAGAAAT
TGGAGAAGGACGAGATCATCAAGTTGTATAGCTGTATCATTGGCAACATGATTTCGAAAGGCTTCCCAACTGATGCAACTCTTGATGACA
TAAAAGAATGGTTAGAAGATAAAGGTCAAGTACTAAATATTCAGATGAGAAGAACATTGCATAAAGCATTTAAGGGATCAATTTTTGTTG
TGTTTGATAGCATTGAATCTGCTAAGAAATTTGTAGAGACCCCTGGCCAGAAGTACAAAGAAACAGACCTGCTAATACTTTTCAAGGACG
ATTACTTTGCCAAAAAAAATGAAGAAAGAAAACAAAATAAAGTGGAAGCTAAATTAAGAGCTAAACAGGAGCAAGAAGCAAAACAAAAGT
TAGAAGAAGATGCTGAAATGAAATCTCTAGAAGAAAAGATTGGATGCTTGCTGAAATTTTCGGGTGATTTAGATGATCAGACCTGTAGAG
AAGATTTACACATACTTTTCTCAAATCATGGTGAAATAAAATGGATAGACTTCGTCAGAGGAGCAAAAGAGGGGATAATTCTATTTAAAG
AAAAAGCCAAGGAAGCATTGGGTAAAGCCAAAGATGCAAATAATGGTAACCTACAATTAAGGAACAAAGAAGTGACTTGGGAAGTACTAG
AAGGAGAGGTGGAAAAAGAAGCACTGAAGAAAATAATAGAAGACCAACAAGAATCCCTAAACAAATGGAAGTCAAAAGGTCGTAGATTTA
AAGGAAAAGGAAAGGGTAATAAAGCTGCCCAGCCTGGGTCTGGTAAAGGAAAAGTACAGTTTCAGGGCAAGAAAACGAAATTTGCTAGTG
ATGATGAACATGATGAACATGATGAAAATGGTGCAACTGGACCTGTGAAAAGAGCAAGAGAAGAAACAGACAAAGAAGAACCTGCATCCA
AACAACAGAAAACAGAAAATGGTGCTGGAGACCAGTAGTTTAGTAAACCAATTTTTTATTCATTTTAAATAGGTTTTAAACGACTTTTGT
TTGCGGGGCTTTTAAAAGGAAAACCGAATTAGGTCCACTTCAATGTCCACCTGTGAGAAAGGAAAAATTTTTTTGTTGTTTAACTTGTCT
TTTTGTTATGCAAATGAGATTTCTTTGAATGTATTGTTCTGTTTGTGTTATTTCAGATGATTCAAATATCAAAAGGAAGATTCTTCCATT

>16896_16896_4_CKAP5-SSB_CKAP5_chr11_46776438_ENST00000529230_SSB_chr2_170663295_ENST00000409333_length(amino acids)=1916AA_BP=1623
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ
RMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLEELGC
LVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRCEMPELVQHKLDDIFEPVLIPEPKIRAVSPH
FDDMHSNTASTINFIISQVASGDINTSIQALTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGN
MISKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVE
AKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG
NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CKAP5-SSB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCKAP5chr11:46776438chr2:170663295ENST00000312055-1431932_195701973.0TACC3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000354558-1421932_195701973.0TACC3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000415402-36441932_19571623.02040.0TACC3
HgeneCKAP5chr11:46776438chr2:170663295ENST00000529230-36441932_19571623.02033.0TACC3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CKAP5-SSB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CKAP5-SSB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource