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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLDN18-ARHGAP6 (FusionGDB2 ID:17035)

Fusion Gene Summary for CLDN18-ARHGAP6

check button Fusion gene summary
Fusion gene informationFusion gene name: CLDN18-ARHGAP6
Fusion gene ID: 17035
HgeneTgene
Gene symbol

CLDN18

ARHGAP6

Gene ID

51208

395

Gene nameclaudin 18Rho GTPase activating protein 6
SynonymsSFTA5|SFTPJRHOGAP6|RHOGAPX-1
Cytomap

3q22.3

Xp22.2

Type of geneprotein-codingprotein-coding
Descriptionclaudin-18surfactant associated 5surfactant associated protein Jsurfactant, pulmonary associated protein Jrho GTPase-activating protein 6Rho-type GTPase-activating protein RhoGAPX-1rho-type GTPase-activating protein 6
Modification date2020031320200313
UniProtAcc

P56856

O43182

Ensembl transtripts involved in fusion geneENST00000183605, ENST00000343735, 
ENST00000303025, ENST00000380736, 
ENST00000413512, ENST00000491514, 
ENST00000337414, ENST00000380718, 
ENST00000380732, ENST00000534860, 
Fusion gene scores* DoF score8 X 11 X 5=4408 X 5 X 6=240
# samples 139
** MAII scorelog2(13/440*10)=-1.7589919004962
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/240*10)=-1.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CLDN18 [Title/Abstract] AND ARHGAP6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLDN18(137749947)-ARHGAP6(11272827), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CLDN18 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGAP6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-A4Z0-01ACLDN18chr3

137749947

+ARHGAP6chrX

11272827

-


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Fusion Gene ORF analysis for CLDN18-ARHGAP6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000183605ENST00000303025CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-5UTRENST00000183605ENST00000380736CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-5UTRENST00000183605ENST00000413512CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-5UTRENST00000343735ENST00000303025CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-5UTRENST00000343735ENST00000380736CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-5UTRENST00000343735ENST00000413512CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-intronENST00000183605ENST00000491514CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
5CDS-intronENST00000343735ENST00000491514CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000183605ENST00000337414CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000183605ENST00000380718CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000183605ENST00000380732CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000183605ENST00000534860CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000343735ENST00000337414CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000343735ENST00000380718CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000343735ENST00000380732CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-
In-frameENST00000343735ENST00000534860CLDN18chr3

137749947

+ARHGAP6chrX

11272827

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343735CLDN18chr3137749947+ENST00000337414ARHGAP6chrX11272827-6951329533165631771
ENST00000343735CLDN18chr3137749947+ENST00000380718ARHGAP6chrX11272827-5466329533165004562
ENST00000343735CLDN18chr3137749947+ENST00000380732ARHGAP6chrX11272827-4684329533164683456
ENST00000343735CLDN18chr3137749947+ENST00000534860ARHGAP6chrX11272827-5256329533165046576
ENST00000183605CLDN18chr3137749947+ENST00000337414ARHGAP6chrX11272827-7040338434055720771
ENST00000183605CLDN18chr3137749947+ENST00000380718ARHGAP6chrX11272827-5555338434055093562
ENST00000183605CLDN18chr3137749947+ENST00000380732ARHGAP6chrX11272827-4773338434054772455
ENST00000183605CLDN18chr3137749947+ENST00000534860ARHGAP6chrX11272827-5345338434055135576

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343735ENST00000337414CLDN18chr3137749947+ARHGAP6chrX11272827-0.0017075040.9982925
ENST00000343735ENST00000380718CLDN18chr3137749947+ARHGAP6chrX11272827-0.0008436270.99915636
ENST00000343735ENST00000380732CLDN18chr3137749947+ARHGAP6chrX11272827-0.0006868050.99931324
ENST00000343735ENST00000534860CLDN18chr3137749947+ARHGAP6chrX11272827-0.0005722150.99942774
ENST00000183605ENST00000337414CLDN18chr3137749947+ARHGAP6chrX11272827-0.002307950.9976921
ENST00000183605ENST00000380718CLDN18chr3137749947+ARHGAP6chrX11272827-0.001163660.99883634
ENST00000183605ENST00000380732CLDN18chr3137749947+ARHGAP6chrX11272827-0.0009482130.99905175
ENST00000183605ENST00000534860CLDN18chr3137749947+ARHGAP6chrX11272827-0.0007807330.9992193

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Fusion Genomic Features for CLDN18-ARHGAP6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CLDN18-ARHGAP6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:137749947/chrX:11272827)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CLDN18

P56856

ARHGAP6

O43182

FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. {ECO:0000250}.FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology. {ECO:0000269|PubMed:10699171}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000303025013401_6020772.0DomainRho-GAP
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000337414013401_602196975.0DomainRho-GAP
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380718011401_602196766.0DomainRho-GAP
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380732112401_602228691.0DomainRho-GAP
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380736013401_6020772.0DomainRho-GAP
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000303025013342_3520772.0MotifNote=SH3-binding
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000337414013342_352196975.0MotifNote=SH3-binding
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380718011342_352196766.0MotifNote=SH3-binding
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380732112342_352228691.0MotifNote=SH3-binding
TgeneARHGAP6chr3:137749947chrX:11272827ENST00000380736013342_3520772.0MotifNote=SH3-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+15102_1220262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+15144_1740262.0Topological domainExtracellular
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+15196_2610262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+151_60262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+1528_800262.0Topological domainExtracellular
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+15102_1220262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+15144_1740262.0Topological domainExtracellular
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+15196_2610262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+151_60262.0Topological domainCytoplasmic
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+1528_800262.0Topological domainExtracellular
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+15123_1430262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+15175_1950262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+157_270262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000183605+1581_1010262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+15123_1430262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+15175_1950262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+157_270262.0TransmembraneHelical
HgeneCLDN18chr3:137749947chrX:11272827ENST00000343735+1581_1010262.0TransmembraneHelical


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Fusion Gene Sequence for CLDN18-ARHGAP6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17035_17035_1_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000337414_length(transcript)=7040nt_BP=3384nt
GAGCAGACAAGTGCCTCTTGGGCCCGCTTCTCTAACAAATGTAAAAATAATGCCCTTGAACCAGGAGCGAAACTGAGCTATCTAAGGAAA
ACACTGTGAGCAAATACTGAGAGCCTAGGGAAACCATCTGATTAGAAGAGCTCCCCTCAGGAGCGCGTTAGCTTCACACCTTCGGCAGCA
GGAGGGCGGCAGCTTCTCGCAGGCGGCAGGGCGGGCGGCCAGGATCATGTCCACCACCACATGCCAAGTGGTGGCGTTCCTCCTGTCCAT
CCTGGGGCTGGCCGGCTGCATCGCGGCCACCGGGATGGACATGTGGAGCACCCAGGACCTGTACGACAACCCCGTCACCTCCGTGTTCCA
GTACGAAGGGCTCTGGAGGAGCTGCGTGAGGCAGAGTTCAGGCTTCACCGAATGCAGGCCCTATTTCACCATCCTGGGACTTCCAGCCAT
GCTGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCG
CATTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGG
AGTGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGT
TCAGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGC
CTGCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGG
CGGAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAA
AGCCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTAT
GAATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCT
CTCTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAA
GAAAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAA
ACACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGT
TACCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGT
TTCCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTC
CTAAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAAT
GAAAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATT
CTTTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTC
ACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGC
CCTGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAG
GATCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAA
AAAAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAAT
TAAATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGT
CGGTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCT
GGCCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGA
ATTCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCC
CTTTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAA
GAGCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAAT
AGTACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATT
ATGCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACC
AGAGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGG
GTTGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAAT
GAGCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTA
TCCAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTG
AGTATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAGT
GTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGAC
TGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGAG
AAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCAG
GACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTCA
AGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAGG
AGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGAG
GCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTGT
CAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATTT
GACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGAC
CCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCATA
TACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAGC
AAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTCA
TCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTAT
GAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACTC
AGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTCC
AACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGCG
GCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTCT
CCTGGACCAAGGCTTGGGAAAGATCTGTCAGAGGAGCCTTTCGATATCTGGGGAACTTGGCATTCAACATTAAAAAGCGGATCCAAAGAC
CCAGGAATGACAGGTTCCTCTGGAGACATTTTTGAAAGCAGCTCCCTAAGAGCGGGGCCCTGCTCCCTTTCTCAAGGGAACCTGTCCCCA
AATTGGCCTCGGTGGCAGGGGAGCCCCGCAGAGCTGGACAGCGACACGCAGGGGGCTCGGAGGACTCAGGCCGCAGCCCCCGCGACGGAG
GGCAGGGCCCACCCTGCGGTGTCGCGCGCCTGCAGCACGCCCCACGTCCAGGTGGCAGGGAAAGCCGAGCGGCCCACGGCCAGGTCGGAG
CAGTACTTGACCCTGAGCGGCGCCCACGACCTCAGCGAGAGTGAGCTGGATGTGGCCGGGCTGCAGAGCCGGGCCACACCTCAGTGCCAA
AGACCCCATGGGAGTGGGAGGGATGACAAGCGGCCCCCGCCTCCATACCCGGGCCCAGGGAAGCCCGCGGCAGCGGCAGCCTGGATCCAG
GGGCCCCCGGAAGGCGTGGAGACACCCACGGACCAGGGAGGCCAAGCAGCCGAGCGAGAGCAGCAGGTCACGCAGAAAAAACTGAGCAGC
GCCAACTCCCTGCCAGCGGGCGAGCAGGACAGTCCGCGCCTGGGGGACGCTGGCTGGCTCGACTGGCAGAGAGAGCGCTGGCAGATCTGG
GAGCTCCTGTCGACCGACAACCCCGATGCCCTGCCCGAGACGCTGGTCTGAGCCCGCACCCAGCCGAGCCCCCCCTGCCCCGAGCCCCCC
GCCCTCCAGCCCAGGGGGGACCGTGGGTGGTGGCCACTGGCACACTTAGTGTTCTTCTTTCACACTTCTCAAAAGTGACACAAGAGAAAT
CCAGTTCACCTACAGAGGTAGAGCACTCACGCCCCCGCCATTGAGAATAAGGTTCCATTGCGTAGCCAGCCTTAGGAAAAACAAACAGAA
CCCAAACCAGATGGCAATGTCCAATCTAAAAACGTCCCTCTTGGCTCTATAATATAAGATACAACTCTTGCTTGGTATAGCCTAACCGTA
TTTATGTGTCTTCGGTTTTGACTATTGTGTATTCTGTAACAGATTATGTATAATCATATATGATATATTCACAAAGAGAAAACAAAAGGA
ACTTTTAAAAAAAAAATCACTTCACTTATATTAAGCAATGAGATATACTAAACAATGAGATTCTATAGAATGTTCTAGAATGTGCACAAG
CGGGTTTCTGTGCTTTTGCCATAGCTTTATAACTGGGGATAACCCTTCCTTCGATACCAAACACTAACAAGAGGAAGCAGAATATGAGAA
GCCATATTTTTACATAGGAGTCAGATACAAAAAGAAAAATCACTGAATGCTTTTAGATATTGAATACGTTTTCAGGAAAATGCTAAATCT
GATAGATTACGAAATATATTTTTAGAACTTGTTTAGAAAGGATTCAGTTAACCAAACAAGAAAAAGGCAGTGCCTCACAAAGAAATTAAG
AAGTTGTCCGTCCCACGTTACATCAAATTCAGTTTTATATAGGCCATATATAATATATATTTATAATGTATAATTTTTATGTATTTTTCA
AAACTACAAACTGGAATCCAACTATAAAGTGTTTAAGAATCTACACAGAATATTCAAATTATAGAACATGTTTTTTCCCTTTGCCCCATA
ATCAGTATTTGCCAAATTACATGCAATTCCTTAAAAACTAAATCACATTTGGTAAAAGGCCTACAGCTTTGTACTTACATTGTGCCAAAG
GCTGAGGAAATGTTTTCTTTCGTAATTTTATGTGTATTGTAAAATGTTCTACCGTACTTTAGTAGTTTGAAGTTTTTCAAGTGCATAACT
ATTTTTGACCAGCAGATGGCGATACGCTTCAGTATTTTATGCAATTTTTTTTCACTTCTGAAGGGAAAGTGTATTATAAAAAAAGATTTT
TTTTTTTTTTATAAAACATGCTACTCTTAATTTTCATGTTGGTGATGAAATTCCCAGTGGTGTTTCTTAAGGTTCTATCTTGTGCCATGA

>17035_17035_1_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000337414_length(amino acids)=771AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTLK
SGSKDPGMTGSSGDIFESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERP
TARSEQYLTLSGAHDLSESELDVAGLQSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGPPEGVETPTDQGGQAAEREQQVTQ

--------------------------------------------------------------
>17035_17035_2_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000380718_length(transcript)=5555nt_BP=3384nt
GAGCAGACAAGTGCCTCTTGGGCCCGCTTCTCTAACAAATGTAAAAATAATGCCCTTGAACCAGGAGCGAAACTGAGCTATCTAAGGAAA
ACACTGTGAGCAAATACTGAGAGCCTAGGGAAACCATCTGATTAGAAGAGCTCCCCTCAGGAGCGCGTTAGCTTCACACCTTCGGCAGCA
GGAGGGCGGCAGCTTCTCGCAGGCGGCAGGGCGGGCGGCCAGGATCATGTCCACCACCACATGCCAAGTGGTGGCGTTCCTCCTGTCCAT
CCTGGGGCTGGCCGGCTGCATCGCGGCCACCGGGATGGACATGTGGAGCACCCAGGACCTGTACGACAACCCCGTCACCTCCGTGTTCCA
GTACGAAGGGCTCTGGAGGAGCTGCGTGAGGCAGAGTTCAGGCTTCACCGAATGCAGGCCCTATTTCACCATCCTGGGACTTCCAGCCAT
GCTGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCG
CATTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGG
AGTGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGT
TCAGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGC
CTGCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGG
CGGAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAA
AGCCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTAT
GAATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCT
CTCTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAA
GAAAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAA
ACACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGT
TACCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGT
TTCCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTC
CTAAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAAT
GAAAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATT
CTTTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTC
ACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGC
CCTGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAG
GATCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAA
AAAAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAAT
TAAATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGT
CGGTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCT
GGCCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGA
ATTCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCC
CTTTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAA
GAGCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAAT
AGTACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATT
ATGCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACC
AGAGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGG
GTTGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAAT
GAGCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTA
TCCAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTG
AGTATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAGT
GTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGAC
TGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGAG
AAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCAG
GACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTCA
AGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAGG
AGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGAG
GCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTGT
CAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATTT
GACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGAC
CCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCATA
TACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAGC
AAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTCA
TCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTAT
GAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACTC
AGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTCC
AACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGCG
GCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTCT
CCTGGACCAAGGCTTGGGAAAGGTAACTGGAGCCTGGCCAGCAGGCGCTGGCCAAAACAAGCGACCCTCCTCTTGTTGCATGTGGCATGG
TGTGGGGCTCTTCGGACCTTCTCTTCGTCTCTCCCTTATTTGATGTTTCTGTAATTCAACCTGCATTTACCGAGTACCTGCTGAACGCCT
ACTCTAGGAAGAGGAAGGTATGGCGAGCCCAGTCGTTGGCTGGGAGGGTCCCTGCAGGCCACACTCCAAGTCTCAGATATCTGGGAAATA
AACGCATGCCCAGAGGAGCCACTCCTATTCCCAGCTGATTCTTTTTCCCTCCAGCATCCTAGGAACTTTATGTATACTGGATTTGGGTTG
CATATTTGCTAGTCTGAGGTGCCACCCAATTACTGCTGTTACATTTCTAAAGAAAACAAGCTGAACCTACTATATGTATGAAGACAACCT
TCCAGAACCAAATAGTGTTAGTATCCAATGACAAGAGAGCACTATACTGGGAGTCACAAACCTGCTCTGCCACTTTCAACCTGCAGGATC

>17035_17035_2_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000380718_length(amino acids)=562AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKGNWSLASRRWPKQATLLL

--------------------------------------------------------------
>17035_17035_3_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000380732_length(transcript)=4773nt_BP=3384nt
GAGCAGACAAGTGCCTCTTGGGCCCGCTTCTCTAACAAATGTAAAAATAATGCCCTTGAACCAGGAGCGAAACTGAGCTATCTAAGGAAA
ACACTGTGAGCAAATACTGAGAGCCTAGGGAAACCATCTGATTAGAAGAGCTCCCCTCAGGAGCGCGTTAGCTTCACACCTTCGGCAGCA
GGAGGGCGGCAGCTTCTCGCAGGCGGCAGGGCGGGCGGCCAGGATCATGTCCACCACCACATGCCAAGTGGTGGCGTTCCTCCTGTCCAT
CCTGGGGCTGGCCGGCTGCATCGCGGCCACCGGGATGGACATGTGGAGCACCCAGGACCTGTACGACAACCCCGTCACCTCCGTGTTCCA
GTACGAAGGGCTCTGGAGGAGCTGCGTGAGGCAGAGTTCAGGCTTCACCGAATGCAGGCCCTATTTCACCATCCTGGGACTTCCAGCCAT
GCTGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCG
CATTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGG
AGTGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGT
TCAGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGC
CTGCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGG
CGGAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAA
AGCCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTAT
GAATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCT
CTCTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAA
GAAAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAA
ACACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGT
TACCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGT
TTCCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTC
CTAAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAAT
GAAAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATT
CTTTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTC
ACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGC
CCTGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAG
GATCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAA
AAAAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAAT
TAAATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGT
CGGTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCT
GGCCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGA
ATTCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCC
CTTTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAA
GAGCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAAT
AGTACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATT
ATGCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACC
AGAGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGG
GTTGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAAT
GAGCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTA
TCCAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTG
AGTATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAGT
GTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGAC
TGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGAG
AAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCAG
GACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTCA
AGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAGG
AGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGAG
GCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTGT
CAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATTT
GACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGAC
CCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCATA
TACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAGC
AAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTCA
TCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTAT
GAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACTC
AGAAGAAAGGCTTCCCAATCATCAACAAGTTCTGTGCTTCCGGCTGCAGTGCAGGCCTGCCCACAGTACCCTGCCAGCATGTTTACGCCC

>17035_17035_3_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000380732_length(amino acids)=455AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSTSSVLPAAVQACPQYPA

--------------------------------------------------------------
>17035_17035_4_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000534860_length(transcript)=5345nt_BP=3384nt
GAGCAGACAAGTGCCTCTTGGGCCCGCTTCTCTAACAAATGTAAAAATAATGCCCTTGAACCAGGAGCGAAACTGAGCTATCTAAGGAAA
ACACTGTGAGCAAATACTGAGAGCCTAGGGAAACCATCTGATTAGAAGAGCTCCCCTCAGGAGCGCGTTAGCTTCACACCTTCGGCAGCA
GGAGGGCGGCAGCTTCTCGCAGGCGGCAGGGCGGGCGGCCAGGATCATGTCCACCACCACATGCCAAGTGGTGGCGTTCCTCCTGTCCAT
CCTGGGGCTGGCCGGCTGCATCGCGGCCACCGGGATGGACATGTGGAGCACCCAGGACCTGTACGACAACCCCGTCACCTCCGTGTTCCA
GTACGAAGGGCTCTGGAGGAGCTGCGTGAGGCAGAGTTCAGGCTTCACCGAATGCAGGCCCTATTTCACCATCCTGGGACTTCCAGCCAT
GCTGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCG
CATTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGG
AGTGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGT
TCAGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGC
CTGCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGG
CGGAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAA
AGCCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTAT
GAATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCT
CTCTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAA
GAAAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAA
ACACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGT
TACCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGT
TTCCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTC
CTAAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAAT
GAAAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATT
CTTTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTC
ACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGC
CCTGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAG
GATCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAA
AAAAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAAT
TAAATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGT
CGGTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCT
GGCCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGA
ATTCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCC
CTTTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAA
GAGCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAAT
AGTACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATT
ATGCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACC
AGAGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGG
GTTGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAAT
GAGCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTA
TCCAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTG
AGTATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAGT
GTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGAC
TGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGAG
AAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCAG
GACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTCA
AGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAGG
AGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGAG
GCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTGT
CAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATTT
GACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGAC
CCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCATA
TACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAGC
AAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTCA
TCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTAT
GAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACTC
AGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTCC
AACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGCG
GCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTCT
CCTGGACCAAGGCTTGGGAAAGATCTGTCAGAGGAGCCTTTCGATATCTGGGGAACTTGGCATTCAACATTAAAAAGCGGATCCAAAGAC
CCAGGAATGACAGGAACTACTCCTCTCCTTAACATCTCTTCTCAAGAGGATCACAGGCAAAAAGATCTAAGGCTCATTTTCAAGATTTAC
CCATGATCATGGAGCAGCACTATAAATCCAAAGCTACTATAGAAGCATTGAAAACAAATATAAAAGGTTCACCTTAGTCTCATTTTACTG
AGTCACAGTAAACCAGACTTACAGAATCATCTATTTTTAAGGTGACAATTGTTCAGATAGTACCACTGATCAATGATCCCCTAACTTTTT

>17035_17035_4_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000183605_ARHGAP6_chrX_11272827_ENST00000534860_length(amino acids)=576AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTLK

--------------------------------------------------------------
>17035_17035_5_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000337414_length(transcript)=6951nt_BP=3295nt
AACCGCCTCCATTACATGGTCCGTTCCTGACGTGTACACCAGCCTCTCAGAGAAAACTCCATCCCTACACTCGGTAGTCTCAGAATTGCG
CTGTCCACTTGTCGTGTGGCTCTGTGTCGACACTGTGCGCCACCATGGCCGTGACTGCCTGTCAGGGCTTGGGGTTCGTGGTTTCACTGA
TTGGGATTGCGGGCATCATTGCTGCCACCTGCATGGACCAGTGGAGCACCCAAGACTTGTACAACAACCCCGTAACAGCTGTTTTCAACT
ACCAGGGGCTGTGGCGCTCCTGTGTCCGAGAGAGCTCTGGCTTCACCGAGTGCCGGGGCTACTTCACCCTGCTGGGGCTGCCAGCCATGC
TGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCGCA
TTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGGAG
TGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGTTC
AGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGCCT
GCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGGCG
GAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAAAG
CCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTATGA
ATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCTCT
CTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAAGA
AAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAAAC
ACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGTTA
CCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGTTT
CCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTCCT
AAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAATGA
AAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATTCT
TTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTCAC
GCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGCCC
TGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAGGA
TCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAAAA
AAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAATTA
AATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGTCG
GTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCTGG
CCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGAAT
TCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCCCT
TTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAAGA
GCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAATAG
TACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATTAT
GCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACCAG
AGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGGGT
TGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAATGA
GCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTATC
CAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTGAG
TATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGTTGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAG
TGTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGA
CTGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGA
GAAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCA
GGACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTC
AAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAG
GAGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGA
GGCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTG
TCAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATT
TGACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGA
CCCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCAT
ATACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAG
CAAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTC
ATCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTA
TGAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACT
CAGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTC
CAACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGC
GGCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTC
TCCTGGACCAAGGCTTGGGAAAGATCTGTCAGAGGAGCCTTTCGATATCTGGGGAACTTGGCATTCAACATTAAAAAGCGGATCCAAAGA
CCCAGGAATGACAGGTTCCTCTGGAGACATTTTTGAAAGCAGCTCCCTAAGAGCGGGGCCCTGCTCCCTTTCTCAAGGGAACCTGTCCCC
AAATTGGCCTCGGTGGCAGGGGAGCCCCGCAGAGCTGGACAGCGACACGCAGGGGGCTCGGAGGACTCAGGCCGCAGCCCCCGCGACGGA
GGGCAGGGCCCACCCTGCGGTGTCGCGCGCCTGCAGCACGCCCCACGTCCAGGTGGCAGGGAAAGCCGAGCGGCCCACGGCCAGGTCGGA
GCAGTACTTGACCCTGAGCGGCGCCCACGACCTCAGCGAGAGTGAGCTGGATGTGGCCGGGCTGCAGAGCCGGGCCACACCTCAGTGCCA
AAGACCCCATGGGAGTGGGAGGGATGACAAGCGGCCCCCGCCTCCATACCCGGGCCCAGGGAAGCCCGCGGCAGCGGCAGCCTGGATCCA
GGGGCCCCCGGAAGGCGTGGAGACACCCACGGACCAGGGAGGCCAAGCAGCCGAGCGAGAGCAGCAGGTCACGCAGAAAAAACTGAGCAG
CGCCAACTCCCTGCCAGCGGGCGAGCAGGACAGTCCGCGCCTGGGGGACGCTGGCTGGCTCGACTGGCAGAGAGAGCGCTGGCAGATCTG
GGAGCTCCTGTCGACCGACAACCCCGATGCCCTGCCCGAGACGCTGGTCTGAGCCCGCACCCAGCCGAGCCCCCCCTGCCCCGAGCCCCC
CGCCCTCCAGCCCAGGGGGGACCGTGGGTGGTGGCCACTGGCACACTTAGTGTTCTTCTTTCACACTTCTCAAAAGTGACACAAGAGAAA
TCCAGTTCACCTACAGAGGTAGAGCACTCACGCCCCCGCCATTGAGAATAAGGTTCCATTGCGTAGCCAGCCTTAGGAAAAACAAACAGA
ACCCAAACCAGATGGCAATGTCCAATCTAAAAACGTCCCTCTTGGCTCTATAATATAAGATACAACTCTTGCTTGGTATAGCCTAACCGT
ATTTATGTGTCTTCGGTTTTGACTATTGTGTATTCTGTAACAGATTATGTATAATCATATATGATATATTCACAAAGAGAAAACAAAAGG
AACTTTTAAAAAAAAAATCACTTCACTTATATTAAGCAATGAGATATACTAAACAATGAGATTCTATAGAATGTTCTAGAATGTGCACAA
GCGGGTTTCTGTGCTTTTGCCATAGCTTTATAACTGGGGATAACCCTTCCTTCGATACCAAACACTAACAAGAGGAAGCAGAATATGAGA
AGCCATATTTTTACATAGGAGTCAGATACAAAAAGAAAAATCACTGAATGCTTTTAGATATTGAATACGTTTTCAGGAAAATGCTAAATC
TGATAGATTACGAAATATATTTTTAGAACTTGTTTAGAAAGGATTCAGTTAACCAAACAAGAAAAAGGCAGTGCCTCACAAAGAAATTAA
GAAGTTGTCCGTCCCACGTTACATCAAATTCAGTTTTATATAGGCCATATATAATATATATTTATAATGTATAATTTTTATGTATTTTTC
AAAACTACAAACTGGAATCCAACTATAAAGTGTTTAAGAATCTACACAGAATATTCAAATTATAGAACATGTTTTTTCCCTTTGCCCCAT
AATCAGTATTTGCCAAATTACATGCAATTCCTTAAAAACTAAATCACATTTGGTAAAAGGCCTACAGCTTTGTACTTACATTGTGCCAAA
GGCTGAGGAAATGTTTTCTTTCGTAATTTTATGTGTATTGTAAAATGTTCTACCGTACTTTAGTAGTTTGAAGTTTTTCAAGTGCATAAC
TATTTTTGACCAGCAGATGGCGATACGCTTCAGTATTTTATGCAATTTTTTTTCACTTCTGAAGGGAAAGTGTATTATAAAAAAAGATTT
TTTTTTTTTTTATAAAACATGCTACTCTTAATTTTCATGTTGGTGATGAAATTCCCAGTGGTGTTTCTTAAGGTTCTATCTTGTGCCATG

>17035_17035_5_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000337414_length(amino acids)=771AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTLK
SGSKDPGMTGSSGDIFESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERP
TARSEQYLTLSGAHDLSESELDVAGLQSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGPPEGVETPTDQGGQAAEREQQVTQ

--------------------------------------------------------------
>17035_17035_6_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000380718_length(transcript)=5466nt_BP=3295nt
AACCGCCTCCATTACATGGTCCGTTCCTGACGTGTACACCAGCCTCTCAGAGAAAACTCCATCCCTACACTCGGTAGTCTCAGAATTGCG
CTGTCCACTTGTCGTGTGGCTCTGTGTCGACACTGTGCGCCACCATGGCCGTGACTGCCTGTCAGGGCTTGGGGTTCGTGGTTTCACTGA
TTGGGATTGCGGGCATCATTGCTGCCACCTGCATGGACCAGTGGAGCACCCAAGACTTGTACAACAACCCCGTAACAGCTGTTTTCAACT
ACCAGGGGCTGTGGCGCTCCTGTGTCCGAGAGAGCTCTGGCTTCACCGAGTGCCGGGGCTACTTCACCCTGCTGGGGCTGCCAGCCATGC
TGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCGCA
TTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGGAG
TGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGTTC
AGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGCCT
GCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGGCG
GAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAAAG
CCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTATGA
ATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCTCT
CTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAAGA
AAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAAAC
ACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGTTA
CCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGTTT
CCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTCCT
AAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAATGA
AAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATTCT
TTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTCAC
GCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGCCC
TGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAGGA
TCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAAAA
AAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAATTA
AATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGTCG
GTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCTGG
CCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGAAT
TCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCCCT
TTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAAGA
GCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAATAG
TACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATTAT
GCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACCAG
AGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGGGT
TGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAATGA
GCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTATC
CAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTGAG
TATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGTTGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAG
TGTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGA
CTGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGA
GAAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCA
GGACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTC
AAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAG
GAGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGA
GGCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTG
TCAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATT
TGACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGA
CCCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCAT
ATACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAG
CAAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTC
ATCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTA
TGAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACT
CAGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTC
CAACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGC
GGCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTC
TCCTGGACCAAGGCTTGGGAAAGGTAACTGGAGCCTGGCCAGCAGGCGCTGGCCAAAACAAGCGACCCTCCTCTTGTTGCATGTGGCATG
GTGTGGGGCTCTTCGGACCTTCTCTTCGTCTCTCCCTTATTTGATGTTTCTGTAATTCAACCTGCATTTACCGAGTACCTGCTGAACGCC
TACTCTAGGAAGAGGAAGGTATGGCGAGCCCAGTCGTTGGCTGGGAGGGTCCCTGCAGGCCACACTCCAAGTCTCAGATATCTGGGAAAT
AAACGCATGCCCAGAGGAGCCACTCCTATTCCCAGCTGATTCTTTTTCCCTCCAGCATCCTAGGAACTTTATGTATACTGGATTTGGGTT
GCATATTTGCTAGTCTGAGGTGCCACCCAATTACTGCTGTTACATTTCTAAAGAAAACAAGCTGAACCTACTATATGTATGAAGACAACC
TTCCAGAACCAAATAGTGTTAGTATCCAATGACAAGAGAGCACTATACTGGGAGTCACAAACCTGCTCTGCCACTTTCAACCTGCAGGAT

>17035_17035_6_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000380718_length(amino acids)=562AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKGNWSLASRRWPKQATLLL

--------------------------------------------------------------
>17035_17035_7_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000380732_length(transcript)=4684nt_BP=3295nt
AACCGCCTCCATTACATGGTCCGTTCCTGACGTGTACACCAGCCTCTCAGAGAAAACTCCATCCCTACACTCGGTAGTCTCAGAATTGCG
CTGTCCACTTGTCGTGTGGCTCTGTGTCGACACTGTGCGCCACCATGGCCGTGACTGCCTGTCAGGGCTTGGGGTTCGTGGTTTCACTGA
TTGGGATTGCGGGCATCATTGCTGCCACCTGCATGGACCAGTGGAGCACCCAAGACTTGTACAACAACCCCGTAACAGCTGTTTTCAACT
ACCAGGGGCTGTGGCGCTCCTGTGTCCGAGAGAGCTCTGGCTTCACCGAGTGCCGGGGCTACTTCACCCTGCTGGGGCTGCCAGCCATGC
TGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCGCA
TTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGGAG
TGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGTTC
AGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGCCT
GCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGGCG
GAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAAAG
CCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTATGA
ATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCTCT
CTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAAGA
AAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAAAC
ACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGTTA
CCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGTTT
CCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTCCT
AAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAATGA
AAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATTCT
TTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTCAC
GCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGCCC
TGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAGGA
TCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAAAA
AAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAATTA
AATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGTCG
GTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCTGG
CCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGAAT
TCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCCCT
TTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAAGA
GCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAATAG
TACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATTAT
GCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACCAG
AGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGGGT
TGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAATGA
GCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTATC
CAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTGAG
TATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGTTGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAG
TGTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGA
CTGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGA
GAAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCA
GGACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTC
AAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAG
GAGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGA
GGCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTG
TCAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATT
TGACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGA
CCCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCAT
ATACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAG
CAAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTC
ATCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTA
TGAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACT
CAGAAGAAAGGCTTCCCAATCATCAACAAGTTCTGTGCTTCCGGCTGCAGTGCAGGCCTGCCCACAGTACCCTGCCAGCATGTTTACGCC

>17035_17035_7_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000380732_length(amino acids)=456AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSTSSVLPAAVQACPQYPA

--------------------------------------------------------------
>17035_17035_8_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000534860_length(transcript)=5256nt_BP=3295nt
AACCGCCTCCATTACATGGTCCGTTCCTGACGTGTACACCAGCCTCTCAGAGAAAACTCCATCCCTACACTCGGTAGTCTCAGAATTGCG
CTGTCCACTTGTCGTGTGGCTCTGTGTCGACACTGTGCGCCACCATGGCCGTGACTGCCTGTCAGGGCTTGGGGTTCGTGGTTTCACTGA
TTGGGATTGCGGGCATCATTGCTGCCACCTGCATGGACCAGTGGAGCACCCAAGACTTGTACAACAACCCCGTAACAGCTGTTTTCAACT
ACCAGGGGCTGTGGCGCTCCTGTGTCCGAGAGAGCTCTGGCTTCACCGAGTGCCGGGGCTACTTCACCCTGCTGGGGCTGCCAGCCATGC
TGCAGGCAGTGCGAGCCCTGATGATCGTAGGCATCGTCCTGGGTGCCATTGGCCTCCTGGTATCCATCTTTGCCCTGAAATGCATCCGCA
TTGGCAGCATGGAGGACTCTGCCAAAGCCAACATGACACTGACCTCCGGGATCATGTTCATTGTCTCAGGTCTTTGTGCAATTGCTGGAG
TGTCTGTGTTTGCCAACATGCTGGTGACTAACTTCTGGATGTCCACAGCTAACATGTACACCGGCATGGGTGGGATGGTGCAGACTGTTC
AGACCAGGTACACATTTGGTGCGGCTCTGTTCGTGGGCTGGGTCGCTGGAGGCCTCACACTAATTGGGGGTGTGATGATGTGCATCGCCT
GCCGGGGCCTGGCACCAGAAGAAACCAAGTACAATCTTATCCTTCCAAGCACGACTATGTGTAATGCTCTAAGACCTCTCAGCACGGGCG
GAAGAAACTCCCGGAGAGCTCACCCAAAAAACAAGGAGATCCCATCTAGATTTCTTCTTGCTTTTGACTCACAGCTGGAAGTTAGAAAAG
CCTCGATTTCATCTTTGGAGAGGCCAAATGGTCTTAGCCTCAGTCTCTGTCTCTAAATATTCCACCATAAAACAGCTGAGTTATTTATGA
ATTAGAGGCTATAGCTCACATTTTCAATCCTCTATTTCTTTTTTTAAATATAACTTTCTACTCTGATGAGAGAATGTGGTTTTAATCTCT
CTCTCACATTTTGATGATTTAGACAGACTCCCCCTCTTCCTCCTAGTCAATAAACCCATTGATGATCTATTTCCCAGCTTATCCCCAAGA
AAACTTTTGAAAGGAAAGAGTAGACCCAAAGATGTTATTTTCTGCTGTTTGAATTTTGTCTCCCCACCCCCAACTTGGCTAGTAATAAAC
ACTTACTGAAGAAGAAGCAATAAGAGAAAGATATTTGTAATCTCTCCAGCCCATGATCTCGGTTTTCTTACACTGTGATCTTAAAAGTTA
CCAAACCAAAGTCATTTTCAGTTTGAGGCAACCAAACCTTTCTACTGCTGTTGACATCTTCTTATTACAGCAACACCATTCTAGGAGTTT
CCTGAGCTCTCCACTGGAGTCCTCTTTCTGTCGCGGGTCAGAAATTGTCCCTAGATGAATGAGAAAATTATTTTTTTTAATTTAAGTCCT
AAATATAGTTAAAATAAATAATGTTTTAGTAAAATGATACACTATCTCTGTGAAATAGCCTCACCCCTACATGTGGATAGAAGGAAATGA
AAAAATAATTGCTTTGACATTGTCTATATGGTACTTTGTAAAGTCATGCTTAAGTACAAATTCCATGAAAAGCTCACTGATCCTAATTCT
TTCCCTTTGAGGTCTCTATGGCTCTGATTGTACATGATAGTAAGTGTAAGCCATGTAAAAAGTAAATAATGTCTGGGCACAGTGGCTCAC
GCCTGTAATCCTAGCACTTTGGGAGGCTGAGGAGGAAGGATCACTTGAGCCCAGAAGTTCGAGACTAGCCTGGGCAACATGGAGAAGCCC
TGTCTCTACAAAATACAGAGAGAAAAAATCAGCCAGTCATGGTGGCCTACACCTGTAGTCCCAGCATTCCGGGAGGCTGAGGTGGGAGGA
TCACTTGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCAGGTGACATAGCGAGATCCTGTCTAAAA
AAATAAAAAATAAATAATGGAACACAGCAAGTCCTAGGAAGTAGGTTAAAACTAATTCTTTAAAAAAAAAAAAAAGTTGAGCCTGAATTA
AATGTAATGTTTCCAAGTGACAGGTATCCACATTTGCATGGTTACAAGCCACTGCCAGTTAGCAGTAGCACTTTCCTGGCACTGTGGTCG
GTTTTGTTTTGTTTTGCTTTGTTTAGAGACGGGGTCTCACTTTCCAGGCTGGCCTCAAACTCCTGCACTCAAGCAATTCTTCTACCCTGG
CCTCCCAAGTAGCTGGAATTACAGGTGTGCGCCATCACAACTAGCTGGTGGTCAGTTTTGTTACTCTGAGAGCTGTTCACTTCTCTGAAT
TCACCTAGAGTGGTTGGACCATCAGATGTTTGGGCAAAACTGAAAGCTCTTTGCAACCACACACCTTCCCTGAGCTTACATCACTGCCCT
TTTGAGCAGAAAGTCTAAATTCCTTCCAAGACAGTAGAATTCCATCCCAGTACCAAAGCCAGATAGGCCCCCTAGGAAACTGAGGTAAGA
GCAGTCTCTAAAAACTACCCACAGCAGCATTGGTGCAGGGGAACTTGGCCATTAGGTTATTATTTGAGAGGAAAGTCCTCACATCAATAG
TACATATGAAAGTGACCTCCAAGGGGATTGGTGAATACTCATAAGGATCTTCAGGCTGAACAGACTATGTCTGGGGAAAGAACGGATTAT
GCCCCATTAAATAACAAGTTGTGTTCAAGAGTCAGAGCAGTGAGCTCAGAGGCCCTTCTCACTGAGACAGCAACATTTAAACCAAACCAG
AGGAAGTATTTGTGGAACTCACTGCCTCAGTTTGGGTAAAGGATGAGCAGACAAGTCAACTAAAGAAAAAAGAAAAGCAAGGAGGAGGGT
TGAGCAATCTAGAGCATGGAGTTTGTTAAGTGCTCTCTGGATTTGAGTTGAAGAGCATCCATTTGAGTTGAAGGCCACAGGGCACAATGA
GCTCTCCCTTCTACCACCAGAAAGTCCCTGGTCAGGTCTCAGGTAGTGCGGTGTGGCTCAGCTGGGTTTTTAATTAGCGCATTCTCTATC
CAACATTTAATTGTTTGAAAGCCTCCATATAGTTAGATTGTGCTTTGTAATTTTGTTGTTGTTGCTCTATCTTATTGTATATGCATTGAG
TATTAACCTGAATGTTTTGTTACTTAAATATTAAAAACACTGTTATCCTACAGTTGGTGATTTCACCTGGAACAGCATGTCAGGCCGCAG
TGTACGGCTGAGGTCAGTCCCCATCCAGAGTCTCTCAGAGCTGGAGAGGGCCCGGCTGCAGGAAGTGGCTTTTTATCAGTTGCAACAGGA
CTGTGACCTGAGCTGTCAGATCACCATTCCCAAAGATGGACAAAAGAGAAAGAAATCTTTAAGAAAGAAACTGGATTCACTAGGAAAGGA
GAAAAACAAAGACAAAGAATTCATCCCACAGGCATTTGGAATGCCCTTATCCCAAGTCATTGCGAATGACAGGGCCTATAAACTCAAGCA
GGACTTGCAGAGGGACGAGCAGAAAGATGCATCTGACTTTGTGGCTTCCCTCCTCCCATTTGGAAATAAAAGACAAAACAAAGAACTCTC
AAGCAGTAACTCATCTCTCAGCTCAACCTCAGAAACACCGAATGAGTCAACGTCCCCAAACACCCCGGAACCGGCTCCTCGGGCTAGGAG
GAGGGGTGCCATGTCAGTGGATTCTATCACCGATCTTGATGACAATCAGTCTCGACTACTAGAAGCTTTACAACTTTCCTTGCCTGCTGA
GGCTCAAAGTAAAAAGGAAAAAGCCAGAGATAAGAAACTCAGTCTGAATCCTATTTACAGACAGGTCCCTAGGCTGGTGGACAGCTGCTG
TCAGCACCTAGAAAAACATGGCCTCCAGACAGTGGGGATATTCCGAGTTGGAAGCTCAAAAAAGAGAGTGAGACAATTACGTGAGGAATT
TGACCGTGGGATTGATGTCTCTCTGGAGGAGGAGCACAGTGTTCATGATGTGGCAGCCTTGCTGAAAGAGTTCCTGAGGGACATGCCAGA
CCCCCTTCTCACCAGGGAGCTGTACACAGCTTTCATCAACACTCTCTTGTTGGAGCCGGAGGAACAGCTGGGCACCTTGCAGCTCCTCAT
ATACCTTCTACCTCCCTGCAACTGCGACACCCTCCACCGCCTGCTACAGTTCCTCTCCATCGTGGCCAGGCATGCCGATGACAACATCAG
CAAAGATGGGCAAGAGGTCACTGGGAATAAAATGACATCTCTAAACTTAGCCACCATATTTGGACCCAACCTGCTGCACAAGCAGAAGTC
ATCAGACAAAGAATTCTCAGTTCAGAGTTCAGCCCGGGCTGAGGAGAGCACGGCCATCATCGCTGTTGTGCAAAAGATGATTGAAAATTA
TGAAGCCCTGTTCATGGTTCCCCCAGATCTCCAGAACGAAGTGCTGATCAGCCTGTTAGAGACCGATCCTGATGTCGTGGACTATTTACT
CAGAAGAAAGGCTTCCCAATCATCAAGCCCTGACATGCTGCAGTCGGAAGTTTCCTTTTCCGTGGGAGGGAGGCATTCATCTACAGACTC
CAACAAGGCCTCCAGCGGAGACATCTCCCCTTATGACAACAACTCCCCAGTGCTGTCTGAGCGCTCCCTGCTGGCTATGCAAGAGGACGC
GGCCCCGGGGGGCTCGGAGAAGCTTTACAGAGTGCCAGGGCAGTTTATGCTGGTGGGCCACTTGTCGTCGTCAAAGTCAAGGGAAAGTTC
TCCTGGACCAAGGCTTGGGAAAGATCTGTCAGAGGAGCCTTTCGATATCTGGGGAACTTGGCATTCAACATTAAAAAGCGGATCCAAAGA
CCCAGGAATGACAGGAACTACTCCTCTCCTTAACATCTCTTCTCAAGAGGATCACAGGCAAAAAGATCTAAGGCTCATTTTCAAGATTTA
CCCATGATCATGGAGCAGCACTATAAATCCAAAGCTACTATAGAAGCATTGAAAACAAATATAAAAGGTTCACCTTAGTCTCATTTTACT
GAGTCACAGTAAACCAGACTTACAGAATCATCTATTTTTAAGGTGACAATTGTTCAGATAGTACCACTGATCAATGATCCCCTAACTTTT

>17035_17035_8_CLDN18-ARHGAP6_CLDN18_chr3_137749947_ENST00000343735_ARHGAP6_chrX_11272827_ENST00000534860_length(amino acids)=576AA_BP=
MSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
YKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQL
SLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFL
RDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLL
HKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRH
SSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTLK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CLDN18-ARHGAP6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLDN18-ARHGAP6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLDN18-ARHGAP6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource