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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CLDN4-GLT8D1 (FusionGDB2 ID:17050) |
Fusion Gene Summary for CLDN4-GLT8D1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CLDN4-GLT8D1 | Fusion gene ID: 17050 | Hgene | Tgene | Gene symbol | CLDN4 | GLT8D1 | Gene ID | 1364 | 55830 |
| Gene name | claudin 4 | glycosyltransferase 8 domain containing 1 | |
| Synonyms | CPE-R|CPER|CPETR|CPETR1|WBSCR8|hCPE-R | AD-017|MSTP139 | |
| Cytomap | 7q11.23 | 3p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | claudin-4CPE-receptorClostridium perfringens enterotoxin receptor 1Williams-Beuren syndrome chromosomal region 8 protein | glycosyltransferase 8 domain-containing protein 1glycosyltransferase AD-017 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | O14493 | Q68CQ7 | |
| Ensembl transtripts involved in fusion gene | ENST00000340958, ENST00000431918, ENST00000435050, ENST00000466411, | ENST00000463827, ENST00000266014, ENST00000394783, ENST00000407584, ENST00000478968, ENST00000491606, | |
| Fusion gene scores | * DoF score | 5 X 5 X 3=75 | 7 X 6 X 6=252 |
| # samples | 5 | 9 | |
| ** MAII score | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/252*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CLDN4 [Title/Abstract] AND GLT8D1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CLDN4(73245883)-GLT8D1(52734352), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | CLDN4-GLT8D1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across CLDN4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GLT8D1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS5.0 | N/A | BF757832 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
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Fusion Gene ORF analysis for CLDN4-GLT8D1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000340958 | ENST00000463827 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| 5CDS-intron | ENST00000431918 | ENST00000463827 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| 5CDS-intron | ENST00000435050 | ENST00000463827 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| Frame-shift | ENST00000431918 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| Frame-shift | ENST00000431918 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| Frame-shift | ENST00000431918 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| Frame-shift | ENST00000431918 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| Frame-shift | ENST00000431918 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000340958 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000340958 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000340958 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000340958 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000340958 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000435050 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000435050 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000435050 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000435050 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| In-frame | ENST00000435050 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-3CDS | ENST00000466411 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-3CDS | ENST00000466411 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-3CDS | ENST00000466411 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-3CDS | ENST00000466411 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-3CDS | ENST00000466411 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| intron-intron | ENST00000466411 | ENST00000463827 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000435050 | CLDN4 | chr7 | 73245883 | + | ENST00000478968 | GLT8D1 | chr3 | 52734352 | + | 2641 | 1209 | 16 | 486 | 156 |
| ENST00000435050 | CLDN4 | chr7 | 73245883 | + | ENST00000394783 | GLT8D1 | chr3 | 52734352 | + | 2638 | 1209 | 16 | 486 | 156 |
| ENST00000435050 | CLDN4 | chr7 | 73245883 | + | ENST00000407584 | GLT8D1 | chr3 | 52734352 | + | 2638 | 1209 | 16 | 486 | 156 |
| ENST00000435050 | CLDN4 | chr7 | 73245883 | + | ENST00000266014 | GLT8D1 | chr3 | 52734352 | + | 2638 | 1209 | 16 | 486 | 156 |
| ENST00000435050 | CLDN4 | chr7 | 73245883 | + | ENST00000491606 | GLT8D1 | chr3 | 52734352 | + | 2627 | 1209 | 853 | 68 | 261 |
| ENST00000340958 | CLDN4 | chr7 | 73245883 | + | ENST00000478968 | GLT8D1 | chr3 | 52734352 | + | 2563 | 1131 | 174 | 530 | 118 |
| ENST00000340958 | CLDN4 | chr7 | 73245883 | + | ENST00000394783 | GLT8D1 | chr3 | 52734352 | + | 2560 | 1131 | 174 | 530 | 118 |
| ENST00000340958 | CLDN4 | chr7 | 73245883 | + | ENST00000407584 | GLT8D1 | chr3 | 52734352 | + | 2560 | 1131 | 174 | 530 | 118 |
| ENST00000340958 | CLDN4 | chr7 | 73245883 | + | ENST00000266014 | GLT8D1 | chr3 | 52734352 | + | 2560 | 1131 | 174 | 530 | 118 |
| ENST00000340958 | CLDN4 | chr7 | 73245883 | + | ENST00000491606 | GLT8D1 | chr3 | 52734352 | + | 2549 | 1131 | 775 | 2 | 258 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000435050 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.48955333 | 0.51044667 |
| ENST00000435050 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.6262834 | 0.37371653 |
| ENST00000435050 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.6262834 | 0.37371653 |
| ENST00000435050 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.6262834 | 0.37371653 |
| ENST00000435050 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.532357 | 0.46764302 |
| ENST00000340958 | ENST00000478968 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.2419032 | 0.7580968 |
| ENST00000340958 | ENST00000394783 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.23163617 | 0.76836383 |
| ENST00000340958 | ENST00000407584 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.23163617 | 0.76836383 |
| ENST00000340958 | ENST00000266014 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.23163617 | 0.76836383 |
| ENST00000340958 | ENST00000491606 | CLDN4 | chr7 | 73245883 | + | GLT8D1 | chr3 | 52734352 | + | 0.15087399 | 0.849126 |
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Fusion Genomic Features for CLDN4-GLT8D1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CLDN4-GLT8D1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:73245883/chr3:52734352) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CLDN4 | GLT8D1 |
| FUNCTION: Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. {ECO:0000250|UniProtKB:O35054}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000266014 | 0 | 10 | 1_7 | 0 | 372.0 | Topological domain | Cytoplasmic | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000266014 | 0 | 10 | 29_371 | 0 | 372.0 | Topological domain | Lumenal | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000394783 | 0 | 10 | 1_7 | 0 | 372.0 | Topological domain | Cytoplasmic | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000394783 | 0 | 10 | 29_371 | 0 | 372.0 | Topological domain | Lumenal | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000407584 | 0 | 11 | 1_7 | 0 | 372.0 | Topological domain | Cytoplasmic | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000407584 | 0 | 11 | 29_371 | 0 | 372.0 | Topological domain | Lumenal | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000478968 | 0 | 11 | 1_7 | 0 | 372.0 | Topological domain | Cytoplasmic | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000478968 | 0 | 11 | 29_371 | 0 | 372.0 | Topological domain | Lumenal | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000491606 | 0 | 10 | 1_7 | 0 | 372.0 | Topological domain | Cytoplasmic | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000491606 | 0 | 10 | 29_371 | 0 | 372.0 | Topological domain | Lumenal | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000266014 | 0 | 10 | 8_28 | 0 | 372.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000394783 | 0 | 10 | 8_28 | 0 | 372.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000407584 | 0 | 11 | 8_28 | 0 | 372.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000478968 | 0 | 11 | 8_28 | 0 | 372.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein | |
| Tgene | GLT8D1 | chr7:73245883 | chr3:52734352 | ENST00000491606 | 0 | 10 | 8_28 | 0 | 372.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 103_117 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 139_160 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 182_209 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 1_7 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 29_81 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 103_117 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 139_160 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 182_209 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 1_7 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 29_81 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 103_117 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 139_160 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 182_209 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 1_7 | 0 | 210.0 | Topological domain | Cytoplasmic |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 29_81 | 0 | 210.0 | Topological domain | Extracellular |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 118_138 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 161_181 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 82_102 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 8_28 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 118_138 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 161_181 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 82_102 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 8_28 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 118_138 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 161_181 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 82_102 | 0 | 210.0 | Transmembrane | Helical |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 8_28 | 0 | 210.0 | Transmembrane | Helical |
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Fusion Gene Sequence for CLDN4-GLT8D1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >17050_17050_1_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000266014_length(transcript)=2560nt_BP=1131nt TGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCT ACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCG GGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACT ACGTGTAAGGTGCCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCC CTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCAC TCGGACAACTTCCCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTG GTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCA TTTACATTTTCCCCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAA CCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAG GTGCTGTAAACAGGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCT CACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAG GGAGGAGGGGACAGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATT CATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAA AGGCTGCCAAGTTACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTC CAGACCCAACAGGCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATT TCTCAGGAAGTCCTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTG TCAGCTAGGTAAAGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACC AAGTGTTTTCTTACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTG TTGGTTTTAATTTTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCA TCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATT GGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAAC CTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATAC AGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTT AACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGG CTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGAC CAGGGGGAATCCATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGA GACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTC GCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAAC >17050_17050_1_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000266014_length(amino acids)=118AA_BP= MAGGCFAATVHPAQTSLTPPSILLPALLLPATTCKVPRLHSVPLCFVLPWTELSAGCDPRRALPRATGCWGLGTGQRLSQAGRQQPSASL -------------------------------------------------------------- >17050_17050_2_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000394783_length(transcript)=2560nt_BP=1131nt TGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCT ACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCG GGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACT ACGTGTAAGGTGCCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCC CTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCAC TCGGACAACTTCCCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTG GTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCA TTTACATTTTCCCCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAA CCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAG GTGCTGTAAACAGGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCT CACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAG GGAGGAGGGGACAGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATT CATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAA AGGCTGCCAAGTTACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTC CAGACCCAACAGGCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATT TCTCAGGAAGTCCTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTG TCAGCTAGGTAAAGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACC AAGTGTTTTCTTACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTG TTGGTTTTAATTTTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCA TCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATT GGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAAC CTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATAC AGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTT AACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGG CTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGAC CAGGGGGAATCCATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGA GACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTC GCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAAC >17050_17050_2_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000394783_length(amino acids)=118AA_BP= MAGGCFAATVHPAQTSLTPPSILLPALLLPATTCKVPRLHSVPLCFVLPWTELSAGCDPRRALPRATGCWGLGTGQRLSQAGRQQPSASL -------------------------------------------------------------- >17050_17050_3_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000407584_length(transcript)=2560nt_BP=1131nt TGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCT ACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCG GGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACT ACGTGTAAGGTGCCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCC CTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCAC TCGGACAACTTCCCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTG GTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCA TTTACATTTTCCCCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAA CCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAG GTGCTGTAAACAGGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCT CACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAG GGAGGAGGGGACAGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATT CATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAA AGGCTGCCAAGTTACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTC CAGACCCAACAGGCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATT TCTCAGGAAGTCCTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTG TCAGCTAGGTAAAGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACC AAGTGTTTTCTTACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTG TTGGTTTTAATTTTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCA TCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATT GGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAAC CTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATAC AGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTT AACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGG CTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGAC CAGGGGGAATCCATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGA GACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTC GCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAAC >17050_17050_3_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000407584_length(amino acids)=118AA_BP= MAGGCFAATVHPAQTSLTPPSILLPALLLPATTCKVPRLHSVPLCFVLPWTELSAGCDPRRALPRATGCWGLGTGQRLSQAGRQQPSASL -------------------------------------------------------------- >17050_17050_4_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000478968_length(transcript)=2563nt_BP=1131nt TGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCT ACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCG GGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACT ACGTGTAAGGTGCCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCC CTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCAC TCGGACAACTTCCCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTG GTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCA TTTACATTTTCCCCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAA CCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAG GTGCTGTAAACAGGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCT CACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAG GGAGGAGGGGACAGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATT CATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAA AGGCTGCCAAGTTACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTC CAGACCCAACAGGCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATT TCTCAGGAAGTCCTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTG TCAGCTAGGTAAAGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACC AAGTGTTTTCTTACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTG TTGGTTTTAATTTTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAATAGAGGGACTGTATAGCAGAACCCTGGCTGGTA GCATCACAACACCTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTAC ATTGGCTATCTTGACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCA AACCTGACGGAATGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAA TACAGCACTGAAGCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCA GTTAACCTTTGCAAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCC TGGCTCAACAGTGATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCT GACCAGGGGGAATCCATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATG GGAGACAAGAGGAGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACA CTCGCTCCAATGTGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCAT >17050_17050_4_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000478968_length(amino acids)=118AA_BP= MAGGCFAATVHPAQTSLTPPSILLPALLLPATTCKVPRLHSVPLCFVLPWTELSAGCDPRRALPRATGCWGLGTGQRLSQAGRQQPSASL -------------------------------------------------------------- >17050_17050_5_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000491606_length(transcript)=2549nt_BP=1131nt TGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCT ACAATCCGCTGGTGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCG GGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACT ACGTGTAAGGTGCCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCC CTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCAC TCGGACAACTTCCCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTG GTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCA TTTACATTTTCCCCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAA CCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAG GTGCTGTAAACAGGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCT CACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAG GGAGGAGGGGACAGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATT CATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAA AGGCTGCCAAGTTACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTC CAGACCCAACAGGCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATT TCTCAGGAAGTCCTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTG TCAGCTAGGTAAAGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACC AAGTGTTTTCTTACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTG TTGGTTTTAATTTTGTAACCTGTGGCCTGATCTGTAAATAAAACAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCT CCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTTGA CTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATG GAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAAGC CAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGCAA GGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGTGA TTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATC CATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAG ATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTG ATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTT >17050_17050_5_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000340958_GLT8D1_chr3_52734352_ENST00000491606_length(amino acids)=258AA_BP= MHFPGRWVGKASAILLGAGFGEQGTVPEVISRPTRNRGDAGRQSGENVNGDSGQRRCRQIPKSGLSYPGQQKPAPHSTTTPCHFRPSPIS RGGWTLFLLAGGGLGKLSEWAREAEGCCLPAWLSLCPVPSPQQPVARGRALLGSQPALSSVQGRTKQRGTEWSRGTLHVVAGSSRAGSRI -------------------------------------------------------------- >17050_17050_6_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000266014_length(transcript)=2638nt_BP=1209nt CACTTGTGCTGAGCTACTGGCTGATCCCCAAGGACATCCTTCTGGCCTCTCCTTCACACCTGGGTCCCCTAGCCCTGCTGATCGTGGCGG GCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGG TGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCGGGGGGCTGCTTT GCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTG CCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCCCTGCCACGGGCC ACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTC CCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTGGTGGTGGAGTGG GGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCATTTACATTTTCC CCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAACCCGCGCCCAGG AGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACA GGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCTCACCCGCTTCAG CCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGAC AGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATTCATCACTGTAAT TATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAAAGGCTGCCAAGT TACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTCCAGACCCAACAG GCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATTTCTCAGGAAGTC CTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTGTCAGCTAGGTAA AGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACCAAGTGTTTTCTT ACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTGTTGGTTTTAATT TTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTC CTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTTGAC TATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGG AAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCC AGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGCAAG GTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGTGAT TCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCC ATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGA TTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGA TTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTG >17050_17050_6_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000266014_length(amino acids)=156AA_BP= MADPQGHPSGLSFTPGSPSPADRGGRGVPVGRPYGDSAGVLDGPQHHPRLLQSAGGLRAEAGDGCLALRRLGRLRPAAPWRGAALLQLST -------------------------------------------------------------- >17050_17050_7_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000394783_length(transcript)=2638nt_BP=1209nt CACTTGTGCTGAGCTACTGGCTGATCCCCAAGGACATCCTTCTGGCCTCTCCTTCACACCTGGGTCCCCTAGCCCTGCTGATCGTGGCGG GCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGG TGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCGGGGGGCTGCTTT GCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTG CCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCCCTGCCACGGGCC ACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTC CCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTGGTGGTGGAGTGG GGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCATTTACATTTTCC CCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAACCCGCGCCCAGG AGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACA GGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCTCACCCGCTTCAG CCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGAC AGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATTCATCACTGTAAT TATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAAAGGCTGCCAAGT TACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTCCAGACCCAACAG GCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATTTCTCAGGAAGTC CTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTGTCAGCTAGGTAA AGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACCAAGTGTTTTCTT ACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTGTTGGTTTTAATT TTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTC CTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTTGAC TATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGG AAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCC AGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGCAAG GTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGTGAT TCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCC ATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGA TTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGA TTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTG >17050_17050_7_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000394783_length(amino acids)=156AA_BP= MADPQGHPSGLSFTPGSPSPADRGGRGVPVGRPYGDSAGVLDGPQHHPRLLQSAGGLRAEAGDGCLALRRLGRLRPAAPWRGAALLQLST -------------------------------------------------------------- >17050_17050_8_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000407584_length(transcript)=2638nt_BP=1209nt CACTTGTGCTGAGCTACTGGCTGATCCCCAAGGACATCCTTCTGGCCTCTCCTTCACACCTGGGTCCCCTAGCCCTGCTGATCGTGGCGG GCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGG TGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCGGGGGGCTGCTTT GCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTG CCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCCCTGCCACGGGCC ACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTC CCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTGGTGGTGGAGTGG GGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCATTTACATTTTCC CCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAACCCGCGCCCAGG AGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACA GGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCTCACCCGCTTCAG CCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGAC AGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATTCATCACTGTAAT TATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAAAGGCTGCCAAGT TACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTCCAGACCCAACAG GCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATTTCTCAGGAAGTC CTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTGTCAGCTAGGTAA AGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACCAAGTGTTTTCTT ACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTGTTGGTTTTAATT TTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTC CTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTTGAC TATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGG AAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCC AGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGCAAG GTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGTGAT TCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCC ATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGA TTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGA TTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTG >17050_17050_8_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000407584_length(amino acids)=156AA_BP= MADPQGHPSGLSFTPGSPSPADRGGRGVPVGRPYGDSAGVLDGPQHHPRLLQSAGGLRAEAGDGCLALRRLGRLRPAAPWRGAALLQLST -------------------------------------------------------------- >17050_17050_9_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000478968_length(transcript)=2641nt_BP=1209nt CACTTGTGCTGAGCTACTGGCTGATCCCCAAGGACATCCTTCTGGCCTCTCCTTCACACCTGGGTCCCCTAGCCCTGCTGATCGTGGCGG GCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGG TGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCGGGGGGCTGCTTT GCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTG CCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCCCTGCCACGGGCC ACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTC CCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTGGTGGTGGAGTGG GGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCATTTACATTTTCC CCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAACCCGCGCCCAGG AGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACA GGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCTCACCCGCTTCAG CCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGAC AGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATTCATCACTGTAAT TATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAAAGGCTGCCAAGT TACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTCCAGACCCAACAG GCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATTTCTCAGGAAGTC CTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTGTCAGCTAGGTAA AGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACCAAGTGTTTTCTT ACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTGTTGGTTTTAATT TTGTAACCTGTGGCCTGATCTGTAAATAAAACTTACATTTTTCAATAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACAC CTCCTCTGCTTATCGTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTT GACTATAAAAAGGAAAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAA TGGAAACGACAGAATATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAA GCCAGGACATGCAGCTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGC AAGGTTCTACTTGCCAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGT GATTCCCTGAAAAGCATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAA TCCATGAAACCTATTCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGG AGATTCCTGTGGTCATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATG TGATTTTCTACATTGTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGC >17050_17050_9_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000478968_length(amino acids)=156AA_BP= MADPQGHPSGLSFTPGSPSPADRGGRGVPVGRPYGDSAGVLDGPQHHPRLLQSAGGLRAEAGDGCLALRRLGRLRPAAPWRGAALLQLST -------------------------------------------------------------- >17050_17050_10_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000491606_length(transcript)=2627nt_BP=1209nt CACTTGTGCTGAGCTACTGGCTGATCCCCAAGGACATCCTTCTGGCCTCTCCTTCACACCTGGGTCCCCTAGCCCTGCTGATCGTGGCGG GCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCCGGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGG TGGCCTCCGGGCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCTCCTTGGCGGGGGGCTGCTTT GCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGCCAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTG CCACGGCTCCACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCAGGAGGGCCCTGCCACGGGCC ACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCCAGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTC CCAAGGCCGCCTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGACAGGGTGTGGTGGTGGAGTGG GGAGCTGGCTTCTGCTGGCCAGGATAGCTTAACCCTGACTTTGGGATCTGCCTGCATCGGCGTTGGCCACTGTCCCCATTTACATTTTCC CCACTCTGTCTGCCTGCATCTCCTCTGTTCCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCTCACCGAAACCCGCGCCCAGG AGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGTGCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACA GGTTTGGGCAGTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACTCTCTGCCTCACCCGCTTCAG CCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGCCCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGAC AGCTTCACCCTTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAAGAGCTATTCATCACTGTAAT TATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGGTTCCAGTGCTGGAAAACGATATTCACCTCAGTTTGTAAAGGCTGCCAAGT TACTCCATTGGAATGGACATTTGAAGCCATGGGGAAGGACTGCTTCATATACTGATGTTTGGGAAAAATGGTATATTCCAGACCCAACAG GCAAATTCAACCTAATCCGAAGATATACCGAGATCTCAAACATAAAGTGAAACAGAATTTGAACTGTAAGCAAGCATTTCTCAGGAAGTC CTGGAAGATAGCATGCGTGGGAAGTAACAGTTGCTAGGCTTCAATGCCTATCGGTAGCAAGCCATGGAAAAAGATGTGTCAGCTAGGTAA AGATGACAAACTGCCCTGTCTGGCAGTCAGCTTCCCAGACAGACTATAGACTATAAATATGTCTCCATCTGCCTTACCAAGTGTTTTCTT ACTACAATGCTGAATGACTGGAAAGAAGAACTGATATGGCTAGTTCAGCTAGCTGGTACAGATAATTCAAAACTGCTGTTGGTTTTAATT TTGTAACCTGTGGCCTGATCTGTAAATAAAACAGAGGGACTGTATAGCAGAACCCTGGCTGGTAGCATCACAACACCTCCTCTGCTTATC GTATTTTATCAACAGCACTCTACCATCGATCCTATGTGGAATGTCCGCCACCTTGTACAATTACATTGGCTATCTTGACTATAAAAAGGA AAGAATTCGTAAGCTTTCCATGAAAGCCAGCACTTGCTCATTTAATCCTGGAGTTTTTGTTGCAAACCTGACGGAATGGAAACGACAGAA TATAACTAACCAACTGGAAAAATGGATGAAACTCAATGTAGAGTGATATTCTTGCCCTTTACAATACAGCACTGAAGCCAGGACATGCAG CTGCATTTTCAGAAGATTGTGATTCAGCCTCTACTAAAGTTGTCATCCGTGGAGCAGGAAACCAGTTAACCTTTGCAAGGTTCTACTTGC CAATTCTGGTTCCCAGCGCAAAGAAGGCCATATACATGGATGATGATGTAATTGTGCAAGGTCCTGGCTCAACAGTGATTCCCTGAAAAG CATCAGATACAAAATTGTCAATTTTGACCCTAAACTTTTGGAAGGAAAAGTAAAGGAGGATCCTGACCAGGGGGAATCCATGAAACCTAT TCAGGAATTGTAGGGCCTCAACCTATAGACTTTGTCCCAAATGCTCTCCGACATGCAGTAGATGGGAGACAAGAGGAGATTCCTGTGGTC ATCGCTGCATCTGAAGACAGGCTTGGGGGGGCCATTGCAGCTATAAACAGCATTCAGCACAACACTCGCTCCAATGTGATTTTCTACATT GTTACTCTCAACAATACAGCAGACCATCTCCGCTGTTGCTCTCTTCTTACTGGTTTTGCACCATAACTTCCTCAGCTTGAGCAGTTTGTT >17050_17050_10_CLDN4-GLT8D1_CLDN4_chr7_73245883_ENST00000435050_GLT8D1_chr3_52734352_ENST00000491606_length(amino acids)=261AA_BP= MHFPGRWVGKASAILLGAGFGEQGTVPEVISRPTRNRGDAGRQSGENVNGDSGQRRCRQIPKSGLSYPGQQKPAPHSTTTPCHFRPSPIS RGGWTLFLLAGGGLGKLSEWAREAEGCCLPAWLSLCPVPSPQQPVARGRALLGSQPALSSVQGRTKQRGTEWSRGTLHVVAGSSRAGSRI -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CLDN4-GLT8D1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000340958 | + | 1 | 1 | 1_103 | 0 | 210.0 | EPHA2 |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000431918 | + | 1 | 2 | 1_103 | 0 | 210.0 | EPHA2 |
| Hgene | CLDN4 | chr7:73245883 | chr3:52734352 | ENST00000435050 | + | 1 | 2 | 1_103 | 0 | 210.0 | EPHA2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CLDN4-GLT8D1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CLDN4-GLT8D1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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