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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLK2-CD244 (FusionGDB2 ID:17203)

Fusion Gene Summary for CLK2-CD244

check button Fusion gene summary
Fusion gene informationFusion gene name: CLK2-CD244
Fusion gene ID: 17203
HgeneTgene
Gene symbol

CLK2

CD244

Gene ID

9894

51744

Gene nametelomere maintenance 2CD244 molecule
SynonymsCLK2|TEL2|YHFS2B4|NAIL|NKR2B4|Nmrk|SLAMF4
Cytomap

16p13.3

1q23.3

Type of geneprotein-codingprotein-coding
Descriptiontelomere length regulation protein TEL2 homologTEL2, telomere maintenance 2, homologprotein clk-2 homolognatural killer cell receptor 2B4CD244 molecule, natural killer cell receptor 2B4NK cell activation inducing ligand NAILNK cell activation-inducing ligandNK cell type I receptor protein 2B4SLAM family member 4h2B4signaling lymphocytic activation mol
Modification date2020031320200313
UniProtAcc.

Q9BZW8

Ensembl transtripts involved in fusion geneENST00000355560, ENST00000361168, 
ENST00000368361, ENST00000536801, 
ENST00000497188, 		ENST00000481677, 
ENST00000322302, ENST00000368032, 
ENST00000368033, ENST00000368034, 
Fusion gene scores* DoF score5 X 6 X 5=1503 X 2 X 3=18
# samples 64
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CLK2 [Title/Abstract] AND CD244 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLK2(155239279)-CD244(160808839), # samples:3
Anticipated loss of major functional domain due to fusion event.CLK2-CD244 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CLK2-CD244 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CLK2-CD244 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCD244

GO:0002323

natural killer cell activation involved in immune response

11714776

TgeneCD244

GO:0060732

positive regulation of inositol phosphate biosynthetic process

8376943

TgeneCD244

GO:0071663

positive regulation of granzyme B production

11714776

TgeneCD244

GO:1902715

positive regulation of interferon-gamma secretion

11714776

TgeneCD244

GO:2000484

positive regulation of interleukin-8 secretion

8376943


check buttonFusion gene breakpoints across CLK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CD244 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A62V-01ACLK2chr1

155239279

-CD244chr1

160808839

-
ChimerDB4BRCATCGA-AC-A62VCLK2chr1

155239278

-CD244chr1

160808839

-


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Fusion Gene ORF analysis for CLK2-CD244

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000355560ENST00000481677CLK2chr1

155239279

-CD244chr1

160808839

-
5CDS-5UTRENST00000355560ENST00000481677CLK2chr1

155239278

-CD244chr1

160808839

-
5CDS-5UTRENST00000361168ENST00000481677CLK2chr1

155239279

-CD244chr1

160808839

-
5CDS-5UTRENST00000361168ENST00000481677CLK2chr1

155239278

-CD244chr1

160808839

-
5CDS-5UTRENST00000368361ENST00000481677CLK2chr1

155239279

-CD244chr1

160808839

-
5CDS-5UTRENST00000368361ENST00000481677CLK2chr1

155239278

-CD244chr1

160808839

-
5CDS-5UTRENST00000536801ENST00000481677CLK2chr1

155239279

-CD244chr1

160808839

-
5CDS-5UTRENST00000536801ENST00000481677CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000322302CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000322302CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368032CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368032CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368033CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368033CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368034CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000355560ENST00000368034CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000322302CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000322302CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368032CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368032CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368033CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368033CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368034CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000361168ENST00000368034CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000322302CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000322302CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368032CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368032CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368033CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368033CLK2chr1

155239278

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368034CLK2chr1

155239279

-CD244chr1

160808839

-
Frame-shiftENST00000368361ENST00000368034CLK2chr1

155239278

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000322302CLK2chr1

155239279

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000322302CLK2chr1

155239278

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368032CLK2chr1

155239279

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368032CLK2chr1

155239278

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368033CLK2chr1

155239279

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368033CLK2chr1

155239278

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368034CLK2chr1

155239279

-CD244chr1

160808839

-
In-frameENST00000536801ENST00000368034CLK2chr1

155239278

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000322302CLK2chr1

155239279

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000322302CLK2chr1

155239278

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368032CLK2chr1

155239279

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368032CLK2chr1

155239278

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368033CLK2chr1

155239279

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368033CLK2chr1

155239278

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368034CLK2chr1

155239279

-CD244chr1

160808839

-
intron-3CDSENST00000497188ENST00000368034CLK2chr1

155239278

-CD244chr1

160808839

-
intron-5UTRENST00000497188ENST00000481677CLK2chr1

155239279

-CD244chr1

160808839

-
intron-5UTRENST00000497188ENST00000481677CLK2chr1

155239278

-CD244chr1

160808839

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000536801CLK2chr1155239279-ENST00000368034CD244chr1160808839-2202572105917270
ENST00000536801CLK2chr1155239279-ENST00000368033CD244chr1160808839-1179572105917270
ENST00000536801CLK2chr1155239279-ENST00000322302CD244chr1160808839-1091572105917270
ENST00000536801CLK2chr1155239279-ENST00000368032CD244chr1160808839-907572105881258
ENST00000536801CLK2chr1155239278-ENST00000368034CD244chr1160808839-2202572105917270
ENST00000536801CLK2chr1155239278-ENST00000368033CD244chr1160808839-1179572105917270
ENST00000536801CLK2chr1155239278-ENST00000322302CD244chr1160808839-1091572105917270
ENST00000536801CLK2chr1155239278-ENST00000368032CD244chr1160808839-907572105881258

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000536801ENST00000368034CLK2chr1155239279-CD244chr1160808839-0.0072367570.9927632
ENST00000536801ENST00000368033CLK2chr1155239279-CD244chr1160808839-0.0021770890.9978229
ENST00000536801ENST00000322302CLK2chr1155239279-CD244chr1160808839-0.0018468060.99815315
ENST00000536801ENST00000368032CLK2chr1155239279-CD244chr1160808839-0.0015785510.99842143
ENST00000536801ENST00000368034CLK2chr1155239278-CD244chr1160808839-0.0072367570.9927632
ENST00000536801ENST00000368033CLK2chr1155239278-CD244chr1160808839-0.0021770890.9978229
ENST00000536801ENST00000322302CLK2chr1155239278-CD244chr1160808839-0.0018468060.99815315
ENST00000536801ENST00000368032CLK2chr1155239278-CD244chr1160808839-0.0015785510.99842143

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Fusion Genomic Features for CLK2-CD244


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CLK2-CD244


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:155239279/chr1:160808839)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CD244

Q9BZW8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor (PubMed:10359122, PubMed:8376943, PubMed:11714776). Activating function implicates association with SH2D1A and FYN (PubMed:15713798). Downstreaming signaling involves predominantly VAV1, and, to a lesser degree, INPP5D/SHIP1 and CBL. Signal attenuation in the absence of SH2D1A is proposed to be dependent on INPP5D and to a lesser extent PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:10934222, PubMed:15713798). Stimulates NK cell cytotoxicity, production of IFN-gamma and granule exocytosis (PubMed:8376943, PubMed:11714776). Optimal expansion and activation of NK cells seems to be dependent on the engagement of CD244 with CD48 expressed on neighboring NK cells (By similarity). Acts as costimulator in NK activation by enhancing signals by other NK receptors such as NCR3 and NCR1 (PubMed:10741393). At early stages of NK cell differentiation may function as an inhibitory receptor possibly ensuring the self-tolerance of developing NK cells (PubMed:11917118). Involved in the regulation of CD8(+) T-cell proliferation; expression on activated T-cells and binding to CD488 provides costimulatory-like function for neighboring T-cells (By similarity). Inhibits inflammatory responses in dendritic cells (DCs) (By similarity). {ECO:0000250|UniProtKB:Q07763, ECO:0000269|PubMed:10359122, ECO:0000269|PubMed:10741393, ECO:0000269|PubMed:10934222, ECO:0000269|PubMed:11714776, ECO:0000269|PubMed:11917118, ECO:0000269|PubMed:8376943, ECO:0000305|PubMed:15713798}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218131_215126274.0DomainNote=Ig-like 2
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218131_215126274.0DomainNote=Ig-like 2
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218269_274126274.0MotifITSM 1
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218295_300126274.0MotifITSM 2
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218315_320126274.0MotifITSM 3
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218340_345126274.0MotifITSM 4
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228269_274218330.0MotifITSM 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228295_300218330.0MotifITSM 2
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228315_320218330.0MotifITSM 3
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228340_345218330.0MotifITSM 4
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329269_274223371.0MotifITSM 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329295_300223371.0MotifITSM 2
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329315_320223371.0MotifITSM 3
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329340_345223371.0MotifITSM 4
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429269_274218366.0MotifITSM 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429295_300218366.0MotifITSM 2
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429315_320218366.0MotifITSM 3
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429340_345218366.0MotifITSM 4
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218269_274126274.0MotifITSM 1
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218295_300126274.0MotifITSM 2
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218315_320126274.0MotifITSM 3
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218340_345126274.0MotifITSM 4
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228269_274218330.0MotifITSM 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228295_300218330.0MotifITSM 2
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228315_320218330.0MotifITSM 3
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228340_345218330.0MotifITSM 4
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329269_274223371.0MotifITSM 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329295_300223371.0MotifITSM 2
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329315_320223371.0MotifITSM 3
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329340_345223371.0MotifITSM 4
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429269_274218366.0MotifITSM 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429295_300218366.0MotifITSM 2
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429315_320218366.0MotifITSM 3
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429340_345218366.0MotifITSM 4
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218251_370126274.0Topological domainCytoplasmic
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228251_370218330.0Topological domainCytoplasmic
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329251_370223371.0Topological domainCytoplasmic
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429251_370218366.0Topological domainCytoplasmic
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218251_370126274.0Topological domainCytoplasmic
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228251_370218330.0Topological domainCytoplasmic
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329251_370223371.0Topological domainCytoplasmic
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429251_370218366.0Topological domainCytoplasmic
TgeneCD244chr1:155239278chr1:160808839ENST0000032230218230_250126274.0TransmembraneHelical
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228230_250218330.0TransmembraneHelical
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329230_250223371.0TransmembraneHelical
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429230_250218366.0TransmembraneHelical
TgeneCD244chr1:155239279chr1:160808839ENST0000032230218230_250126274.0TransmembraneHelical
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228230_250218330.0TransmembraneHelical
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329230_250223371.0TransmembraneHelical
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429230_250218366.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLK2chr1:155239278chr1:160808839ENST00000361168-313163_479133499.0DomainProtein kinase
HgeneCLK2chr1:155239278chr1:160808839ENST00000368361-313163_479133500.0DomainProtein kinase
HgeneCLK2chr1:155239278chr1:160808839ENST00000536801-313163_479133500.0DomainProtein kinase
HgeneCLK2chr1:155239279chr1:160808839ENST00000361168-313163_479133499.0DomainProtein kinase
HgeneCLK2chr1:155239279chr1:160808839ENST00000368361-313163_479133500.0DomainProtein kinase
HgeneCLK2chr1:155239279chr1:160808839ENST00000536801-313163_479133500.0DomainProtein kinase
HgeneCLK2chr1:155239278chr1:160808839ENST00000361168-313169_177133499.0Nucleotide bindingATP
HgeneCLK2chr1:155239278chr1:160808839ENST00000368361-313169_177133500.0Nucleotide bindingATP
HgeneCLK2chr1:155239278chr1:160808839ENST00000536801-313169_177133500.0Nucleotide bindingATP
HgeneCLK2chr1:155239279chr1:160808839ENST00000361168-313169_177133499.0Nucleotide bindingATP
HgeneCLK2chr1:155239279chr1:160808839ENST00000368361-313169_177133500.0Nucleotide bindingATP
HgeneCLK2chr1:155239279chr1:160808839ENST00000536801-313169_177133500.0Nucleotide bindingATP
TgeneCD244chr1:155239278chr1:160808839ENST000003223021822_127126274.0DomainNote=Ig-like 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803228131_215218330.0DomainNote=Ig-like 2
TgeneCD244chr1:155239278chr1:160808839ENST000003680322822_127218330.0DomainNote=Ig-like 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803329131_215223371.0DomainNote=Ig-like 2
TgeneCD244chr1:155239278chr1:160808839ENST000003680332922_127223371.0DomainNote=Ig-like 1
TgeneCD244chr1:155239278chr1:160808839ENST0000036803429131_215218366.0DomainNote=Ig-like 2
TgeneCD244chr1:155239278chr1:160808839ENST000003680342922_127218366.0DomainNote=Ig-like 1
TgeneCD244chr1:155239279chr1:160808839ENST000003223021822_127126274.0DomainNote=Ig-like 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803228131_215218330.0DomainNote=Ig-like 2
TgeneCD244chr1:155239279chr1:160808839ENST000003680322822_127218330.0DomainNote=Ig-like 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803329131_215223371.0DomainNote=Ig-like 2
TgeneCD244chr1:155239279chr1:160808839ENST000003680332922_127223371.0DomainNote=Ig-like 1
TgeneCD244chr1:155239279chr1:160808839ENST0000036803429131_215218366.0DomainNote=Ig-like 2
TgeneCD244chr1:155239279chr1:160808839ENST000003680342922_127218366.0DomainNote=Ig-like 1
TgeneCD244chr1:155239278chr1:160808839ENST000003223021822_229126274.0Topological domainExtracellular
TgeneCD244chr1:155239278chr1:160808839ENST000003680322822_229218330.0Topological domainExtracellular
TgeneCD244chr1:155239278chr1:160808839ENST000003680332922_229223371.0Topological domainExtracellular
TgeneCD244chr1:155239278chr1:160808839ENST000003680342922_229218366.0Topological domainExtracellular
TgeneCD244chr1:155239279chr1:160808839ENST000003223021822_229126274.0Topological domainExtracellular
TgeneCD244chr1:155239279chr1:160808839ENST000003680322822_229218330.0Topological domainExtracellular
TgeneCD244chr1:155239279chr1:160808839ENST000003680332922_229223371.0Topological domainExtracellular
TgeneCD244chr1:155239279chr1:160808839ENST000003680342922_229218366.0Topological domainExtracellular


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Fusion Gene Sequence for CLK2-CD244


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17203_17203_1_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000322302_length(transcript)=1091nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG

>17203_17203_1_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000322302_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

--------------------------------------------------------------
>17203_17203_2_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368032_length(transcript)=907nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGGGTGACAGATTCTATTCATTTTC

>17203_17203_2_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368032_length(amino acids)=258AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL

--------------------------------------------------------------
>17203_17203_3_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368033_length(transcript)=1179nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG
ACGGCACAGGAGTCTCTATAGAACAGTTCCTAGTCTGGAGAGGATATGGAAATTTGTTCTTGTTCTATATTTTGTTTTGAAAATGATGTC

>17203_17203_3_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368033_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

--------------------------------------------------------------
>17203_17203_4_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368034_length(transcript)=2202nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG
ACGGCACAGGAGTCTCTATAGAACAGTTCCTAGTCTGGAGAGGATATGGAAATTTGTTCTTGTTCTATATTTTGTTTTGAAAATGATGTC
TAACAACCATGATAAGAGCAAGGCTGTTAAATAATATCTTCCAATTTACAGATCAGACATGAATGGGTGGAGGGGTTAGGTTGTTCACAA
AAGGCCACATTCCAAGTATTTGTAATCTAGAAAGTGTTATGTAAGTGATGTTATTAGCATCGAGATTCCCTCCACCTGATTTTCAAGCTG
TCACTTGTTTCCTTTTCTCCCCTCTCTGGGTTGACTGCATTTCTAGACTCTCGCCGGCCCAGGCCCATCTTCCAAAGCAAGAGGAAGGAA
TGATAATGGTGACTCAGGGGAAGAAGAAACAGCCCTCCTCTGAAAGCCTGGACTGTCCGGCTGTGAACTGGCTGGCAGGTTCTGCACGTG
GGTGGGGGCCAGGGCCTGGGCTTTACTCAATTGCAGAGAAAAAACTTTCTCCCTGCATCTCATACCTTTACCTCTGGCCAGTTGGCCACC
AGGGGGAGTGGGCTGAAGGGAGAGTAGATGGTGCAAAGCAAGCCCATCTCTAAGTAGAAAAATCACCCAGAGCACATGCTGACCTGATAA
CTGGGGTGTTGAGACCAGCTTTGTCCATGGTATGATGTTTGATTTATGAAGACGCATTGTTAGAAATCCATTTGGCTTCTTCATAGAAGT
GGCTTCCCAGAGGAAGAGGCCTCTCAGAAACCATGTTCTATTTAAGTTCTGAGTCCTGATGAGTGTTCCCCAGGATGCACATTGAAGGGA
GGGCTCAGGCAGCTGAGGGCTGAGAATGAGGCAGTTGGAATCTAGACACTATGCTGGGTTCCCTGAGTCGTCAGGCCAGACATTTCAACA
AGGCTGTGGGGAGCAGGGCTGTGACTCTGGCTGAGCCCAGGAAAGCGACAAGGGTGAACTGGGAGAGGACTTACTCAGAGACCCCAACAG
GTGATACTGCACAAAGCCTGGTTCTTCAATTTTCCTACCCTGTATCTAACATAGGAGTTTCATATAAAACGGTGATATCATGCAGATGCA

>17203_17203_4_CLK2-CD244_CLK2_chr1_155239278_ENST00000536801_CD244_chr1_160808839_ENST00000368034_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

--------------------------------------------------------------
>17203_17203_5_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000322302_length(transcript)=1091nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG

>17203_17203_5_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000322302_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

--------------------------------------------------------------
>17203_17203_6_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368032_length(transcript)=907nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGGGTGACAGATTCTATTCATTTTC

>17203_17203_6_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368032_length(amino acids)=258AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL

--------------------------------------------------------------
>17203_17203_7_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368033_length(transcript)=1179nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG
ACGGCACAGGAGTCTCTATAGAACAGTTCCTAGTCTGGAGAGGATATGGAAATTTGTTCTTGTTCTATATTTTGTTTTGAAAATGATGTC

>17203_17203_7_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368033_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

--------------------------------------------------------------
>17203_17203_8_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368034_length(transcript)=2202nt_BP=572nt
AGATTTGGGGATCGGACCTGAGGCCGCGGTCGCAGGCGGGGGAGCAACGGGAGGCACCGCCTCCAGTCCAGGGGTCGCCCCTTCGCTGGC
CCCCGCCGCCGGCCGCTGCTCTGCCTCCATGGCGCCCACCCCGCTTACACGCTCGGCCTCCTAGAGCCCTCTGTGGCCATCAGATGCCGC
ATCCTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTC
GCTCCTGGTCAAGTAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTT
CGTCCGACCGGAGGGTGTATGACCGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACA
CAGACTATCGGCATTCCTATGAATATCAGCGGGAGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGA
GGCGCAGCCGGACATTTAGCCGCTCATCTTCGAATTCAGATTTTGGCCGTTTTTGGTGATCATCGTGATTCTAAGCGCACTGTTCCTTGG
CACCCTTGCCTGCTTCTGTGTGTGGAGGAGAAAGAGGAAGGAGAAGCAGTCAGAGACCAGTCCCAAGGAATTTTTGACAATTTACGAAGA
TGTCAAGGATCTGAAAACCAGGAGAAATCACGAGCAGGAGCAGACTTTTCCTGGAGGGGGGAGCACCATCTACTCTATGATCCAGTCCCA
GTCTTCTGCTCCCACGTCACAAGAACCTGCATATACATTATATTCATTAATTCAGCCTTCCAGGAAGTCTGGATCCAGGAAGAGGAACCA
CAGCCCTTCCTTCAATAGCACTATCTATGAAGTGATTGGAAAGAGTCAACCTAAAGCCCAGAACCCTGCTCGATTGAGCCGCAAAGAGCT
GGAGAACTTTGATGTTTATTCCTAGTTGCTGCAGCAATTCTCACCTTTCTTGCACATCAGCATCTGCTTTGGGAATTGGCACAGTGGATG
ACGGCACAGGAGTCTCTATAGAACAGTTCCTAGTCTGGAGAGGATATGGAAATTTGTTCTTGTTCTATATTTTGTTTTGAAAATGATGTC
TAACAACCATGATAAGAGCAAGGCTGTTAAATAATATCTTCCAATTTACAGATCAGACATGAATGGGTGGAGGGGTTAGGTTGTTCACAA
AAGGCCACATTCCAAGTATTTGTAATCTAGAAAGTGTTATGTAAGTGATGTTATTAGCATCGAGATTCCCTCCACCTGATTTTCAAGCTG
TCACTTGTTTCCTTTTCTCCCCTCTCTGGGTTGACTGCATTTCTAGACTCTCGCCGGCCCAGGCCCATCTTCCAAAGCAAGAGGAAGGAA
TGATAATGGTGACTCAGGGGAAGAAGAAACAGCCCTCCTCTGAAAGCCTGGACTGTCCGGCTGTGAACTGGCTGGCAGGTTCTGCACGTG
GGTGGGGGCCAGGGCCTGGGCTTTACTCAATTGCAGAGAAAAAACTTTCTCCCTGCATCTCATACCTTTACCTCTGGCCAGTTGGCCACC
AGGGGGAGTGGGCTGAAGGGAGAGTAGATGGTGCAAAGCAAGCCCATCTCTAAGTAGAAAAATCACCCAGAGCACATGCTGACCTGATAA
CTGGGGTGTTGAGACCAGCTTTGTCCATGGTATGATGTTTGATTTATGAAGACGCATTGTTAGAAATCCATTTGGCTTCTTCATAGAAGT
GGCTTCCCAGAGGAAGAGGCCTCTCAGAAACCATGTTCTATTTAAGTTCTGAGTCCTGATGAGTGTTCCCCAGGATGCACATTGAAGGGA
GGGCTCAGGCAGCTGAGGGCTGAGAATGAGGCAGTTGGAATCTAGACACTATGCTGGGTTCCCTGAGTCGTCAGGCCAGACATTTCAACA
AGGCTGTGGGGAGCAGGGCTGTGACTCTGGCTGAGCCCAGGAAAGCGACAAGGGTGAACTGGGAGAGGACTTACTCAGAGACCCCAACAG
GTGATACTGCACAAAGCCTGGTTCTTCAATTTTCCTACCCTGTATCTAACATAGGAGTTTCATATAAAACGGTGATATCATGCAGATGCA

>17203_17203_8_CLK2-CD244_CLK2_chr1_155239279_ENST00000536801_CD244_chr1_160808839_ENST00000368034_length(amino acids)=270AA_BP=154
MLCLHGAHPAYTLGLLEPSVAIRCRILEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQVVVTGHDGVGERTATMSVLEAVMMIVRPTGG
CMTGDTVAATDATIIAGIGEMPTMTQTIGIPMNISGRTAVTAASAAAGGSTDGGGGAAGHLAAHLRIQILAVFGDHRDSKRTVPWHPCLL
LCVEEKEEGEAVRDQSQGIFDNLRRCQGSENQEKSRAGADFSWRGEHHLLYDPVPVFCSHVTRTCIYIIFINSAFQEVWIQEEEPQPFLQ

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Fusion Gene PPI Analysis for CLK2-CD244


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLK2-CD244


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLK2-CD244


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource