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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACTN4-FTO (FusionGDB2 ID:1777)

Fusion Gene Summary for ACTN4-FTO

check button Fusion gene summary
Fusion gene informationFusion gene name: ACTN4-FTO
Fusion gene ID: 1777
HgeneTgene
Gene symbol

ACTN4

FTO

Gene ID

81

79068

Gene nameactinin alpha 4FTO alpha-ketoglutarate dependent dioxygenase
SynonymsACTININ-4|FSGS|FSGS1ALKBH9|BMIQ14|GDFD
Cytomap

19q13.2

16q12.2

Type of geneprotein-codingprotein-coding
Descriptionalpha-actinin-4focal segmental glomerulosclerosis 1non-muscle alpha-actinin 4alpha-ketoglutarate-dependent dioxygenase FTOAlkB homolog 9U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTOU6 small nuclear RNA N(6)-methyladenosine-demethylase FTOfat mass and obesity associatedfat mass and obesity-associated protei
Modification date2020032720200329
UniProtAcc.

Q9C0B1

Ensembl transtripts involved in fusion geneENST00000252699, ENST00000390009, 
ENST00000424234, ENST00000497637, 
ENST00000394647, ENST00000431610, 
ENST00000460382, ENST00000463855, 
ENST00000472835, ENST00000471389, 
Fusion gene scores* DoF score42 X 60 X 18=4536012 X 10 X 7=840
# samples 7715
** MAII scorelog2(77/45360*10)=-5.88041838424733
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/840*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACTN4 [Title/Abstract] AND FTO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACTN4(39138547)-FTO(53844052), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACTN4

GO:0033209

tumor necrosis factor-mediated signaling pathway

25411248

HgeneACTN4

GO:0035357

peroxisome proliferator activated receptor signaling pathway

22351778

HgeneACTN4

GO:0048384

retinoic acid receptor signaling pathway

22351778

HgeneACTN4

GO:0051272

positive regulation of cellular component movement

9508771

TgeneFTO

GO:0006307

DNA dealkylation involved in DNA repair

18775698|20376003

TgeneFTO

GO:0035552

oxidative single-stranded DNA demethylation

18775698|20376003

TgeneFTO

GO:0035553

oxidative single-stranded RNA demethylation

18775698|22002720|25452335|26457839|28002401|30197295

TgeneFTO

GO:0042245

RNA repair

18775698

TgeneFTO

GO:0061157

mRNA destabilization

28002401|30197295

TgeneFTO

GO:0070989

oxidative demethylation

18775698

TgeneFTO

GO:0080111

DNA demethylation

18775698


check buttonFusion gene breakpoints across ACTN4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FTO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A150-01AACTN4chr19

39138546

+FTOchr16

53844051

+
ChimerDB4BRCATCGA-E2-A150-01AACTN4chr19

39138547

-FTOchr16

53844052

+
ChimerDB4BRCATCGA-E2-A150-01AACTN4chr19

39138547

+FTOchr16

53844052

+
ChimerDB4BRCATCGA-E2-A150ACTN4chr19

39138547

+FTOchr16

53844051

+


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Fusion Gene ORF analysis for ACTN4-FTO

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000252699ENST00000394647ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-5UTRENST00000252699ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-5UTRENST00000252699ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-5UTRENST00000390009ENST00000394647ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-5UTRENST00000390009ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-5UTRENST00000390009ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-5UTRENST00000424234ENST00000394647ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-5UTRENST00000424234ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-5UTRENST00000424234ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000431610ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000252699ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000460382ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000252699ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000463855ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000252699ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000472835ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000252699ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000252699ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000431610ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000390009ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000460382ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000390009ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000463855ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000390009ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000472835ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000390009ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000390009ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000431610ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000424234ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000460382ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000424234ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000463855ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000424234ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000472835ACTN4chr19

39138546

+FTOchr16

53844051

+
5CDS-intronENST00000424234ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844052

+
5CDS-intronENST00000424234ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844051

+
In-frameENST00000252699ENST00000471389ACTN4chr19

39138546

+FTOchr16

53844051

+
In-frameENST00000252699ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844052

+
In-frameENST00000252699ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844051

+
In-frameENST00000390009ENST00000471389ACTN4chr19

39138546

+FTOchr16

53844051

+
In-frameENST00000390009ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844052

+
In-frameENST00000390009ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844051

+
In-frameENST00000424234ENST00000471389ACTN4chr19

39138546

+FTOchr16

53844051

+
In-frameENST00000424234ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844052

+
In-frameENST00000424234ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-3CDSENST00000497637ENST00000471389ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-3CDSENST00000497637ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-3CDSENST00000497637ENST00000471389ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-5UTRENST00000497637ENST00000394647ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-5UTRENST00000497637ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-5UTRENST00000497637ENST00000394647ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000431610ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-intronENST00000497637ENST00000431610ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000460382ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-intronENST00000497637ENST00000460382ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000463855ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-intronENST00000497637ENST00000463855ACTN4chr19

39138547

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000472835ACTN4chr19

39138546

+FTOchr16

53844051

+
intron-intronENST00000497637ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844052

+
intron-intronENST00000497637ENST00000472835ACTN4chr19

39138547

+FTOchr16

53844051

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000252699ACTN4chr1939138547+ENST00000471389FTOchr1653844052+11737238761710544
ENST00000424234ACTN4chr1939138547+ENST00000471389FTOchr1653844052+11720221591693544
ENST00000390009ACTN4chr1939138547+ENST00000471389FTOchr1653844052+1166917081642544
ENST00000252699ACTN4chr1939138547+ENST00000471389FTOchr1653844051+11737238761710544
ENST00000424234ACTN4chr1939138547+ENST00000471389FTOchr1653844051+11720221591693544
ENST00000390009ACTN4chr1939138547+ENST00000471389FTOchr1653844051+1166917081642544
ENST00000252699ACTN4chr1939138546+ENST00000471389FTOchr1653844051+11737238761710544
ENST00000424234ACTN4chr1939138546+ENST00000471389FTOchr1653844051+11720221591693544
ENST00000390009ACTN4chr1939138546+ENST00000471389FTOchr1653844051+1166917081642544

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000252699ENST00000471389ACTN4chr1939138547+FTOchr1653844052+0.0018028720.99819714
ENST00000424234ENST00000471389ACTN4chr1939138547+FTOchr1653844052+0.0017746020.9982254
ENST00000390009ENST00000471389ACTN4chr1939138547+FTOchr1653844052+0.0017703550.9982297
ENST00000252699ENST00000471389ACTN4chr1939138547+FTOchr1653844051+0.0018028720.99819714
ENST00000424234ENST00000471389ACTN4chr1939138547+FTOchr1653844051+0.0017746020.9982254
ENST00000390009ENST00000471389ACTN4chr1939138547+FTOchr1653844051+0.0017703550.9982297
ENST00000252699ENST00000471389ACTN4chr1939138546+FTOchr1653844051+0.0018028720.99819714
ENST00000424234ENST00000471389ACTN4chr1939138546+FTOchr1653844051+0.0017746020.9982254
ENST00000390009ENST00000471389ACTN4chr1939138546+FTOchr1653844051+0.0017703550.9982297

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Fusion Genomic Features for ACTN4-FTO


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ACTN4chr1939138547+FTOchr1653844051+1.06E-121
ACTN4chr1939138547+FTOchr1653844051+1.06E-121
ACTN4chr1939138547+FTOchr1653844051+1.06E-121
ACTN4chr1939138547+FTOchr1653844051+1.06E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ACTN4-FTO


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39138547/chr16:53844052)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.FTO

Q9C0B1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis (PubMed:22002720, PubMed:26458103, PubMed:28002401, PubMed:30197295, PubMed:26457839, PubMed:25452335). Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103, PubMed:30197295, PubMed:26457839, PubMed:25452335). M6A demethylation by FTO affects mRNA expression and stability (PubMed:30197295). Also able to demethylate m6A in U6 small nuclear RNA (snRNA) (PubMed:30197295). Mediates demethylation of N(6),2'-O-dimethyladenosine cap (m6A(m)), by demethylating the N(6)-methyladenosine at the second transcribed position of mRNAs and U6 snRNA (PubMed:28002401, PubMed:30197295). Demethylation of m6A(m) in the 5'-cap by FTO affects mRNA stability by promoting susceptibility to decapping (PubMed:28002401). Also acts as a tRNA demethylase by removing N(1)-methyladenine from various tRNAs (PubMed:30197295). Has no activity towards 1-methylguanine (PubMed:20376003). Has no detectable activity towards double-stranded DNA (PubMed:20376003). Also able to repair alkylated DNA and RNA by oxidative demethylation: demethylates single-stranded RNA containing 3-methyluracil, single-stranded DNA containing 3-methylthymine and has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine (PubMed:18775698, PubMed:20376003). Ability to repair alkylated DNA and RNA is however unsure in vivo (PubMed:18775698, PubMed:20376003). Involved in the regulation of fat mass, adipogenesis and body weight, thereby contributing to the regulation of body size and body fat accumulation (PubMed:18775698, PubMed:20376003). Involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (PubMed:26287746). Regulates activity of the dopaminergic midbrain circuitry via its ability to demethylate m6A in mRNAs (By similarity). Plays an oncogenic role in a number of acute myeloid leukemias by enhancing leukemic oncogene-mediated cell transformation: acts by mediating m6A demethylation of target transcripts such as MYC, CEBPA, ASB2 and RARA, leading to promote their expression (PubMed:28017614, PubMed:29249359). {ECO:0000250|UniProtKB:Q8BGW1, ECO:0000269|PubMed:18775698, ECO:0000269|PubMed:20376003, ECO:0000269|PubMed:22002720, ECO:0000269|PubMed:25452335, ECO:0000269|PubMed:26287746, ECO:0000269|PubMed:26457839, ECO:0000269|PubMed:26458103, ECO:0000269|PubMed:28002401, ECO:0000269|PubMed:28017614, ECO:0000269|PubMed:29249359, ECO:0000269|PubMed:30197295}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+11419_2654693.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+11419_2654693.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+11419_2654693.0Compositional biasPoly-Gly
TgeneFTOchr19:39138546chr16:53844051ENST0000043161005213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138546chr16:53844051ENST0000043161005231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138546chr16:53844051ENST0000043161005316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138546chr16:53844051ENST000004316100532_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138546chr16:53844051ENST0000046038204213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138546chr16:53844051ENST0000046038204231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138546chr16:53844051ENST0000046038204316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138546chr16:53844051ENST000004603820432_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138546chr16:53844051ENST0000046385503213_2240128.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138546chr16:53844051ENST0000046385503231_2340128.0RegionSubstrate binding
TgeneFTOchr19:39138546chr16:53844051ENST0000046385503316_3180128.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138546chr16:53844051ENST000004638550332_3270128.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138546chr16:53844051ENST0000047138909213_22415506.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138546chr16:53844051ENST0000047138909231_23415506.0RegionSubstrate binding
TgeneFTOchr19:39138546chr16:53844051ENST0000047138909316_31815506.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138546chr16:53844051ENST000004713890932_32715506.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844051ENST0000043161005213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844051ENST0000043161005231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844051ENST0000043161005316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844051ENST000004316100532_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844051ENST0000046038204213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844051ENST0000046038204231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844051ENST0000046038204316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844051ENST000004603820432_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844051ENST0000046385503213_2240128.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844051ENST0000046385503231_2340128.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844051ENST0000046385503316_3180128.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844051ENST000004638550332_3270128.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844051ENST0000047138909213_22415506.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844051ENST0000047138909231_23415506.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844051ENST0000047138909316_31815506.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844051ENST000004713890932_32715506.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844052ENST0000043161005213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844052ENST0000043161005231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844052ENST0000043161005316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844052ENST000004316100532_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844052ENST0000046038204213_2240107.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844052ENST0000046038204231_2340107.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844052ENST0000046038204316_3180107.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844052ENST000004603820432_3270107.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844052ENST0000046385503213_2240128.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844052ENST0000046385503231_2340128.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844052ENST0000046385503316_3180128.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844052ENST000004638550332_3270128.0RegionFe2OG dioxygenase domain
TgeneFTOchr19:39138547chr16:53844052ENST0000047138909213_22415506.0RegionLoop L1%3B predicted to block binding of double-stranded DNA or RNA
TgeneFTOchr19:39138547chr16:53844052ENST0000047138909231_23415506.0RegionSubstrate binding
TgeneFTOchr19:39138547chr16:53844052ENST0000047138909316_31815506.0RegionAlpha-ketoglutarate binding
TgeneFTOchr19:39138547chr16:53844052ENST000004713890932_32715506.0RegionFe2OG dioxygenase domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114649_75254693.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114649_75254693.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114649_75254693.0RepeatSpectrin 4


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Fusion Gene Sequence for ACTN4-FTO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1777_1777_1_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000252699_FTO_chr16_53844051_ENST00000471389_length(transcript)=11737nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACAC
TTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAG
TGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCA
AGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGT
CCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCT
GCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTT
CCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTT
CATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCT
GGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGA
TCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTT
CATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTG
CTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTT
GAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGG
CAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGC
TGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCA
GAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTG
GGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTA
GAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACT
TCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACC
CTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGT
CCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGA
CCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGC
TGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCC
TCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAA
AAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGA
TTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAAT
TAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACC
AGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGA
TGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTA
ACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAG
ACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTC
CTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTC
CCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGC
TTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCA
GTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCC
TGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATG
AAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTAT
GATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTT
TCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTG
CCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATT
TTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGG
ATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCA
TGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTT
TCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGT
GCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAA
TAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTG
GGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCC
GAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGA
GACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTA
CTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCA
CGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAA
GGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTG
CTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCA
GCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGG
TGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACC
CAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACA
GTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGA
CTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGA
GCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAG
CAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGA
TATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAAC
TGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCT
CCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCA
TGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGA
CCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTT
TCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCT
GTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGG
ATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGG
AGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGA
AAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCAC
TGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAA
ACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGA
CCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTC
CCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTC
TGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGAT
TCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGT
TGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTA
TTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATG
GGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAA
TCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTT
GTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACT
TTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCT
TAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCT
ATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTT
ACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGT
TTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCT
AGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTG
CCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAAT
TCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCC
TGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCT
AAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAA
ACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCC
TTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCC
TCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAAC
ATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTT
TGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCT
TAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAG
GTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGA
CACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAAT
TCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGT
GGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGA
TTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCT
GAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGT
AGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCT
AAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAAC
TAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTT
TTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCT
TTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTG
AAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATG
TGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCC
ACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGA
ATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAA
TACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAA
TATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTT
TCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGG
AAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAAC
AGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGA
TGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGG
AGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATG
TATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCT
GACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTC
ATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATC
TCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGA
GGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTT
GTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCA
GCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTT
TTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACAC
AGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTAT

>1777_1777_1_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000252699_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_2_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000390009_FTO_chr16_53844051_ENST00000471389_length(transcript)=11669nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGC
TTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAAC
TAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTAT
TTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACC
TGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCT
TCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGC
CATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCAT
ACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGA
GCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATG
ACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCC
TTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTT
CCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATG
TGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGC
TGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGA
AGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCC
TTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGA
AGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTC
AGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGC
TTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAG
TTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATG
TGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCT
TTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCC
AATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCC
ACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCC
TATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAA
AAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCAC
ACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTT
ACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAA
GAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAG
CTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTA
AGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGC
TGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGAC
CTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCAC
AGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCC
TGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCT
CTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTA
CAGAGATTAAATGAAATAAATGAAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCC
CAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATT
AAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGA
TCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACC
ACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCAC
CTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATA
GTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATA
CTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCAC
CCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGC
ATCATAAAATATTCATATCCAATAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGA
GCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGA
AATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGA
TCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGG
TGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGC
CACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCA
GGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGG
GTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGC
GGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCT
AAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAG
CAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTA
CCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGA
GAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGG
GACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGA
GAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGG
GCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAA
TCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACA
GAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTC
TAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATG
CCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCA
AATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAA
AAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATT
CAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTA
TTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTT
GTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGAC
AGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGA
GACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCC
CCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCAT
GCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGA
AACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGG
TTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTA
GTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTC
AGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGC
TCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCA
TATCATGTCTGGTACTTAAAAATCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAG
GGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTC
GCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCAC
CCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAAT
GTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCA
GTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGG
ATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCA
CCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGT
GCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCA
GATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTT
TTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGC
GATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACC
ACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACT
ACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGG
CACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGT
GCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTC
GTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACA
GGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATG
AATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATA
AAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTG
ATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAG
TTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCT
GCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTC
TGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCT
CAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCAT
TAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTG
AGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGA
CCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTT
CCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAA
GGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGT
ACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCA
GATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACAC
ACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAAT
TTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACA
TACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAAT
TATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAAC
ATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAG
AACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTA
TTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCA
CCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACG
CAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCA
AAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCG
TGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAA
CCAAAATACTCATGCCAACATCTCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCT
AAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCC
GGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCA
ACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGA
TAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCC
TATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCT

>1777_1777_2_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000390009_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_3_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000424234_FTO_chr16_53844051_ENST00000471389_length(transcript)=11720nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGA
CCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCC
ATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCA
CTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAG
GGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCC
AGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGG
GTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAA
TGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGG
TGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATG
TTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCA
ATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGG
ATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTG
CAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGT
GCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTA
AAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAAT
GGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTT
CGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTC
AGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGAT
TGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGAT
TTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGG
AACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAA
AGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTT
AAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACT
GCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAA
TTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTC
TCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATAT
CCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTT
TTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAA
AGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCT
CATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCA
GCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCC
CTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAA
TAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGT
GCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAA
TGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTC
AGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATGAAATAACATAGACCAGG
AGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTT
ATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTT
TTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTA
ATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGT
TTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCA
CCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATA
AGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCT
GACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATG
TGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAATAAACATATTAAAAGGA
TGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTA
GTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACAT
TTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACA
CGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCA
GGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAA
GAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCC
AATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGG
ACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTG
CTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTA
CCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCC
TCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAAT
AACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTT
GATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGC
CCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCG
GGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGA
TCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGG
CTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGC
AGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACA
CAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCC
ACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGG
CTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACAT
GGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAG
TGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGG
TGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCA
GAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGC
AGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCT
GAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACC
CCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTT
GTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGC
TGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCA
CTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAG
TTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGT
GGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCC
TAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAATCACGCCACGCATGTAC
ATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTG
TGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATAT
TATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCA
TCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAA
GCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTG
AAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTG
CCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCC
TTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCA
AAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTA
GTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAG
TGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATA
GGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTG
ATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGA
TTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGA
GGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTT
GTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAG
AATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCT
GCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATG
CACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGC
ATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGG
AACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCA
ACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAG
TCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGA
ACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATA
CATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTT
AAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAA
GGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGAC
CCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGA
GCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGC
TGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGG
CATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGAC
TGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAG
CAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATA
GGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATT
TTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAAT
TTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCA
CTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGT
TTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTC
AAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGC
CCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTT
TCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAA
TTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTA
ATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATCTCTCTGTACAGAAACAT
GGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGT
GAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAG
ATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTC
GGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGG
TGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTG
TGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTATGTACCCACAAAAATTAA

>1777_1777_3_ACTN4-FTO_ACTN4_chr19_39138546_ENST00000424234_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_4_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000252699_FTO_chr16_53844051_ENST00000471389_length(transcript)=11737nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACAC
TTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAG
TGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCA
AGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGT
CCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCT
GCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTT
CCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTT
CATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCT
GGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGA
TCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTT
CATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTG
CTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTT
GAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGG
CAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGC
TGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCA
GAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTG
GGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTA
GAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACT
TCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACC
CTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGT
CCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGA
CCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGC
TGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCC
TCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAA
AAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGA
TTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAAT
TAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACC
AGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGA
TGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTA
ACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAG
ACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTC
CTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTC
CCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGC
TTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCA
GTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCC
TGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATG
AAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTAT
GATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTT
TCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTG
CCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATT
TTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGG
ATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCA
TGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTT
TCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGT
GCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAA
TAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTG
GGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCC
GAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGA
GACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTA
CTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCA
CGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAA
GGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTG
CTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCA
GCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGG
TGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACC
CAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACA
GTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGA
CTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGA
GCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAG
CAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGA
TATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAAC
TGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCT
CCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCA
TGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGA
CCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTT
TCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCT
GTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGG
ATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGG
AGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGA
AAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCAC
TGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAA
ACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGA
CCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTC
CCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTC
TGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGAT
TCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGT
TGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTA
TTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATG
GGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAA
TCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTT
GTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACT
TTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCT
TAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCT
ATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTT
ACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGT
TTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCT
AGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTG
CCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAAT
TCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCC
TGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCT
AAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAA
ACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCC
TTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCC
TCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAAC
ATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTT
TGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCT
TAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAG
GTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGA
CACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAAT
TCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGT
GGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGA
TTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCT
GAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGT
AGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCT
AAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAAC
TAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTT
TTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCT
TTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTG
AAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATG
TGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCC
ACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGA
ATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAA
TACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAA
TATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTT
TCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGG
AAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAAC
AGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGA
TGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGG
AGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATG
TATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCT
GACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTC
ATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATC
TCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGA
GGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTT
GTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCA
GCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTT
TTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACAC
AGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTAT

>1777_1777_4_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000252699_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_5_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000252699_FTO_chr16_53844052_ENST00000471389_length(transcript)=11737nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACAC
TTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAG
TGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCA
AGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGT
CCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCT
GCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTT
CCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTT
CATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCT
GGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGA
TCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTT
CATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTG
CTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTT
GAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGG
CAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGC
TGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCA
GAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTG
GGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTA
GAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACT
TCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACC
CTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGT
CCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGA
CCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGC
TGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCC
TCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAA
AAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGA
TTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAAT
TAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACC
AGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGA
TGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTA
ACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAG
ACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTC
CTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTC
CCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGC
TTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCA
GTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCC
TGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATG
AAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTAT
GATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTT
TCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTG
CCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATT
TTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGG
ATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCA
TGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTT
TCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGT
GCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAA
TAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTG
GGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCC
GAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGA
GACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTA
CTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCA
CGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAA
GGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTG
CTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCA
GCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGG
TGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACC
CAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACA
GTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGA
CTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGA
GCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAG
CAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGA
TATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAAC
TGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCT
CCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCA
TGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGA
CCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTT
TCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCT
GTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGG
ATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGG
AGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGA
AAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCAC
TGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAA
ACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGA
CCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTC
CCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTC
TGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGAT
TCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGT
TGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTA
TTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATG
GGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAA
TCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTT
GTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACT
TTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCT
TAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCT
ATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTT
ACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGT
TTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCT
AGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTG
CCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAAT
TCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCC
TGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCT
AAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAA
ACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCC
TTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCC
TCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAAC
ATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTT
TGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCT
TAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAG
GTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGA
CACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAAT
TCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGT
GGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGA
TTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCT
GAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGT
AGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCT
AAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAAC
TAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTT
TTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCT
TTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTG
AAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATG
TGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCC
ACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGA
ATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAA
TACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAA
TATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTT
TCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGG
AAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAAC
AGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGA
TGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGG
AGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATG
TATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCT
GACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTC
ATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATC
TCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGA
GGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTT
GTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCA
GCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTT
TTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACAC
AGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTAT

>1777_1777_5_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000252699_FTO_chr16_53844052_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_6_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000390009_FTO_chr16_53844051_ENST00000471389_length(transcript)=11669nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGC
TTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAAC
TAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTAT
TTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACC
TGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCT
TCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGC
CATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCAT
ACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGA
GCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATG
ACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCC
TTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTT
CCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATG
TGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGC
TGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGA
AGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCC
TTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGA
AGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTC
AGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGC
TTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAG
TTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATG
TGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCT
TTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCC
AATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCC
ACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCC
TATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAA
AAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCAC
ACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTT
ACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAA
GAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAG
CTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTA
AGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGC
TGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGAC
CTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCAC
AGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCC
TGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCT
CTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTA
CAGAGATTAAATGAAATAAATGAAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCC
CAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATT
AAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGA
TCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACC
ACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCAC
CTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATA
GTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATA
CTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCAC
CCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGC
ATCATAAAATATTCATATCCAATAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGA
GCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGA
AATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGA
TCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGG
TGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGC
CACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCA
GGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGG
GTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGC
GGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCT
AAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAG
CAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTA
CCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGA
GAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGG
GACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGA
GAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGG
GCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAA
TCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACA
GAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTC
TAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATG
CCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCA
AATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAA
AAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATT
CAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTA
TTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTT
GTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGAC
AGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGA
GACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCC
CCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCAT
GCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGA
AACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGG
TTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTA
GTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTC
AGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGC
TCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCA
TATCATGTCTGGTACTTAAAAATCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAG
GGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTC
GCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCAC
CCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAAT
GTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCA
GTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGG
ATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCA
CCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGT
GCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCA
GATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTT
TTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGC
GATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACC
ACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACT
ACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGG
CACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGT
GCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTC
GTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACA
GGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATG
AATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATA
AAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTG
ATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAG
TTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCT
GCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTC
TGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCT
CAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCAT
TAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTG
AGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGA
CCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTT
CCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAA
GGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGT
ACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCA
GATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACAC
ACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAAT
TTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACA
TACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAAT
TATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAAC
ATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAG
AACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTA
TTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCA
CCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACG
CAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCA
AAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCG
TGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAA
CCAAAATACTCATGCCAACATCTCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCT
AAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCC
GGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCA
ACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGA
TAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCC
TATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCT

>1777_1777_6_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000390009_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_7_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000390009_FTO_chr16_53844052_ENST00000471389_length(transcript)=11669nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGC
TTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGACCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAAC
TAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCCATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTAT
TTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCACTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACC
TGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAGGGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCT
TCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCCAGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGC
CATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGGGTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCAT
ACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAATGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGA
GCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGGTGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATG
ACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATGTTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCC
TTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCAATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTT
CCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGGATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATG
TGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTGCAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGC
TGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGTGCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGA
AGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTAAAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCC
TTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAATGGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGA
AGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTTCGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTC
AGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTCAGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGC
TTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGATTGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAG
TTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGATTTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATG
TGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGGAACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCT
TTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAAAGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCC
AATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTTAAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCC
ACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACTGCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCC
TATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAATTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAA
AAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTCTCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCAC
ACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATATCCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTT
ACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTTTTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAA
GAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAAAGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAG
CTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCTCATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTA
AGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCAGCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGC
TGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCCCTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGAC
CTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAATAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCAC
AGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGTGCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCC
TGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAATGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCT
CTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTCAGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTA
CAGAGATTAAATGAAATAAATGAAATAACATAGACCAGGAGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCC
CAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTTATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATT
AAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGA
TCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACC
ACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGTTTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCAC
CTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCACCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATA
GTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATAAGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATA
CTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCTGACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCAC
CCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATGTGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGC
ATCATAAAATATTCATATCCAATAAACATATTAAAAGGATGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGA
GCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTAGTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGA
AATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACATTTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGA
TCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGG
TGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGC
CACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAAGAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCA
GGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCCAATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGG
GTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGGACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGC
GGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTGCTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCT
AAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTACCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAG
CAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCCTCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTA
CCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAATAACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGA
GAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTTGATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGG
GACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGCCCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGA
GAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCGGGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGG
GCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGATCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAA
TCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGGCTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACA
GAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGCAGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTC
TAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACACAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATG
CCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCCACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCA
AATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGGCTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAA
AAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACATGGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATT
CAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAGTGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTA
TTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGGTGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTT
GTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCAGAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGAC
AGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGCAGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGA
GACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCTGAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCC
CCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACCCCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCAT
GCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTTGTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGA
AACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGCTGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGG
TTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCACTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTA
GTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAGTTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTC
AGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGTGGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGC
TCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCCTAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCA
TATCATGTCTGGTACTTAAAAATCACGCCACGCATGTACATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAG
GGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTGTGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTC
GCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATATTATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCAC
CCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCATCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAAT
GTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAAGCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCA
GTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTGAAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGG
ATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTGCCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCA
CCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCCTTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGT
GCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCAAAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCA
GATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTAGTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTT
TTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAGTGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGC
GATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATAGGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACC
ACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTGATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACT
ACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGATTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGG
CACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGAGGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGT
GCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTTGTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTC
GTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAGAATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACA
GGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCTGCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATG
AATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATGCACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATA
AAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGCATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTG
ATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGGAACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAG
TTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCAACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCT
GCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAGTCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTC
TGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGAACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCT
CAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATACATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCAT
TAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTTAAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTG
AGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAAGGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGA
CCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGACCCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTT
CCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGAGCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAA
GGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGCTGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGT
ACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGGCATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCA
GATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGACTGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACAC
ACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAGCAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAAT
TTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATAGGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACA
TACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATTTTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAAT
TATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAATTTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAAC
ATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCACTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAG
AACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGTTTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTA
TTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTCAAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCA
CCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGCCCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACG
CAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTTTCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCA
AAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAATTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCG
TGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTAATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAA
CCAAAATACTCATGCCAACATCTCTCTGTACAGAAACATGGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCT
AAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGTGAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCC
GGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAGATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCA
ACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTCGGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGA
TAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGGTGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCC
TATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTGTGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCT

>1777_1777_7_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000390009_FTO_chr16_53844052_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_8_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000424234_FTO_chr16_53844051_ENST00000471389_length(transcript)=11720nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGA
CCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCC
ATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCA
CTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAG
GGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCC
AGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGG
GTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAA
TGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGG
TGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATG
TTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCA
ATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGG
ATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTG
CAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGT
GCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTA
AAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAAT
GGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTT
CGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTC
AGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGAT
TGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGAT
TTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGG
AACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAA
AGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTT
AAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACT
GCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAA
TTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTC
TCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATAT
CCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTT
TTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAA
AGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCT
CATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCA
GCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCC
CTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAA
TAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGT
GCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAA
TGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTC
AGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATGAAATAACATAGACCAGG
AGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTT
ATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTT
TTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTA
ATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGT
TTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCA
CCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATA
AGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCT
GACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATG
TGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAATAAACATATTAAAAGGA
TGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTA
GTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACAT
TTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACA
CGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCA
GGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAA
GAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCC
AATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGG
ACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTG
CTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTA
CCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCC
TCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAAT
AACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTT
GATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGC
CCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCG
GGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGA
TCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGG
CTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGC
AGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACA
CAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCC
ACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGG
CTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACAT
GGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAG
TGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGG
TGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCA
GAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGC
AGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCT
GAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACC
CCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTT
GTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGC
TGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCA
CTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAG
TTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGT
GGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCC
TAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAATCACGCCACGCATGTAC
ATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTG
TGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATAT
TATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCA
TCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAA
GCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTG
AAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTG
CCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCC
TTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCA
AAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTA
GTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAG
TGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATA
GGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTG
ATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGA
TTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGA
GGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTT
GTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAG
AATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCT
GCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATG
CACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGC
ATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGG
AACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCA
ACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAG
TCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGA
ACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATA
CATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTT
AAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAA
GGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGAC
CCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGA
GCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGC
TGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGG
CATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGAC
TGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAG
CAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATA
GGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATT
TTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAAT
TTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCA
CTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGT
TTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTC
AAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGC
CCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTT
TCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAA
TTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTA
ATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATCTCTCTGTACAGAAACAT
GGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGT
GAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAG
ATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTC
GGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGG
TGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTG
TGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTATGTACCCACAAAAATTAA

>1777_1777_8_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000424234_FTO_chr16_53844051_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------
>1777_1777_9_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000424234_FTO_chr16_53844052_ENST00000471389_length(transcript)=11720nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAACTGAGGCTTCTTGAAGAGCTTGAAGACACTTGGCTCCCTTATCTGA
CCCCCAAAGATGATGAATTCTATCAGCAGTGGCAGCTGAAATATCCTAAACTAATTCTCCGAGAAGCCAGCAGTGTATCTGAGGAGCTCC
ATAAAGAGGTTCAAGAAGCCTTTCTCACACTGCACAAGCATGGCTGCTTATTTCGGGACCTGGTTAGGATCCAAGGCAAAGATCTGCTCA
CTCCGGTATCTCGCATCCTCATTGGTAATCCAGGCTGCACCTACAAGTACCTGAACACCAGGCTCTTTACGGTCCCCTGGCCAGTGAAAG
GGTCTAATATAAAACACACCGAGGCTGAAATAGCCGCTGCTTGTGAGACCTTCCTCAAGCTCAATGACTACCTGCAGATAGAAACCATCC
AGGCTTTGGAAGAACTTGCTGCCAAAGAGAAGGCTAATGAGGATGCTGTGCCATTGTGTATGTCTGCAGATTTCCCCAGGGTTGGGATGG
GTTCATCCTACAACGGACAAGATGAAGTGGACATTAAGAGCAGAGCAGCATACAACGTAACTTTGCTGAATTTCATGGATCCTCAGAAAA
TGCCATACCTGAAAGAGGAACCTTATTTTGGCATGGGGAAAATGGCAGTGAGCTGGCATCATGATGAAAATCTGGTGGACAGGTCAGCGG
TGGCAGTGTACAGTTATAGCTGTGAAGGCCCTGAAGAGGAAAGTGAGGATGACTCTCATCTCGAAGGCAGGGATCCTGATATTTGGCATG
TTGGTTTTAAGATCTCATGGGACATAGAGACACCTGGTTTGGCGATACCCCTTCACCAAGGAGACTGCTATTTCATGCTTGATGATCTCA
ATGCCACCCACCAACACTGTGTTTTGGCCGGTTCACAACCTCGGTTTAGTTCCACCCACCGAGTGGCAGAGTGCTCAACAGGAACCTTGG
ATTATATTTTACAACGCTGTCAGTTGGCTCTGCAGAATGTCTGTGACGATGTGGACAATGATGATGTCTCTTTGAAATCCTTTGAGCCTG
CAGTTTTGAAACAAGGAGAAGAAATTCATAATGAGGTCGAGTTTGAGTGGCTGAGGCAGTTTTGGTTTCAAGGCAATCGATACAGAAAGT
GCACTGACTGGTGGTGTCAACCCATGGCTCAACTGGAAGCACTGTGGAAGAAGATGGAGGGTGTGACAAATGCTGTGCTTCATGAAGTTA
AAAGAGAGGGGCTCCCCGTGGAACAAAGGAATGAAATCTTGACTGCCATCCTTGCCTCGCTCACTGCACGCCAGAACCTGAGGAGAGAAT
GGCATGCCAGGTGCCAGTCACGAATTGCCCGAACATTACCTGCTGATCAGAAGCCAGAATGTCGGCCATACTGGGAAAAGGATGATGCTT
CGATGCCTCTGCCGTTTGACCTCACAGACATCGTTTCAGAACTCAGAGGTCAGCTTCTGGAAGCAAAACCCTAGAAGGAGCACAAGTCTC
AGGCGGAGGAGAAAAAGAGATCGGCTTTTCTCCTCCAACGTTGTCATGGGCTTAAGCAAGAGCAGTGGAGACTTCTCTTGGCCCCTAGAT
TGTAGCACCCGGGTCCCAATCCAAAACAGCTAGGAAATGGTGCCCATGAAGTTTTAAATGTTTTAAAATGACCCTGTGTTATAGTCTGAT
TTGGTGTTAAACAGGACCTTCTTCCCCCAAAATTGTTCAGATTATAAAATGTGAGCCATTCAGCCCCCAAGGTCCAGGGCAGGCGACAGG
AACGAGCCCAGCGTGTGACAAAGCCTAACCTACTTTCCTCTTTCCCAAGCTTTTTCAGAGACTCTGGAGTGGACCCAGCCCTCTGGGGAA
AGACAGAACTTAGAGACATCCCAGTTACTCACCACACCCATAGTGCTGTCCAATATGGTAGCCACTAGCTAGCTGTGGCTACTTCAATTT
AAATTCAGTTTTAATTTTAATTAAAAATGCAGCTCTTCAGTCGCCCTGGCCACATTTCAAGTGCTTAACAGCCTCATGTGGCTAGTGACT
GCTGTATTGGACGGTACAGATATGGAACATTTTCATCATCGAAGAAAGTCCTATTGGACAACACTTCTATAAAAAGTTTGAGAGCAGGAA
TTCTCATTTCCATTCGTCTGTAGCTTCTATCCCCAAAGGCAAAGAAACTAAAAGAGAAATGACTCATTGAAGATTGGCCTCTTTCCTTTC
TCTAAGACAAACCTAAGTAAAAGCCTGAGCTTTGAGTCCTATGCTCAGCACACGGGAAGGAGATGTTAATAATTAAAATAAAGTTGATAT
CCTGTCTTTAGGGAGTTCCCTTGATCTCTTGAAAGAGACACAGCCCCATTTACATTATTTCGTGGATTTCACCAGCATAGTATAGTTTTT
TTCTGTAAGTCCCTCATTCTTATGTAATAACAGGTGGAACTGAGGTTTGAAGAACCTCAGTGGCCCATCCTGATGACATTGGAGACTCAA
AGAGACAAGAGAGAGTAGGGTTTAAAACCTGAGCTTTAAGACTCCCACTAGCTTCGTGTCCTTTGGCATGTTAACGTGCCTCAGTTTCCT
CATCTGTATAATGGGGATATATGAAAGGCACCAGTCCTAAGGTGAACATTAAGTGAGATGATTCTAGTTACAGACTTAGAACAATTTCCA
GCACATAGTTAAATATCCAGGAAATTCTGGTACTGTTATGTGTGGGTGAGCTGACCTGGATGTAGATGTTTTCCTCTCTCTTGCTGACCC
CTCCGCCAGTTTTGTCTTGTGATGCCATTAACACATCTCTCCCTTTCTGACCTGGCTCCTGCCCATTGGTGTCCCAAGAAATCGTGAGAA
TAGTTAGCCCCCCGTCTCCCCAGCCTGTTGCTTTCTCGTGTAGTTGTTCACAGTAGTTGAGAAGTTGAAGAGCTTTTGCCTATTGAAGGT
GCACTGAGAATAAACTCTTTCCTGCCACCAGAATTGCAGTGGTTCACGGCCTGCACTCATTCCCATGAATGCAGTTAATAGCCACAGAAA
TGTCACATTAAGCAAAGCAGCCAGGGTCTCATCGTGTTGAGACTCGAGTCTCTCAGACCTTGGATTCATTCCCTGGTGTCTTTGAGCCTC
AGTTTCCTCATTGGTAAAAGAGAAGTGAAGCAGTGTCTCACAGGGTCATTACAGAGATTAAATGAAATAAATGAAATAACATAGACCAGG
AGGGCGTGGTGTTTAAAAGTCACAGATGGGGCACCCTCGGGCCATCCAGCCCAGTGTTTTCTTTAGCCCCTATGATGTTCATTTTTTGTT
ATATCCCATTAGGTGCCCATATTTAAAAATTGGGAGATTTCACATAAAATTAAAAGGTCTGCATTTTCTTTTTTCTTTTCTTTTTTTTTT
TTTTTGAGACACAGTCTCACTCTGTCACCAGGCTAGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTA
ATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGCAGAGATGGGGT
TTCACCACATTGGCCAGGATGGTCTCGATCTCAACCTCGTGATCCACCCACCTCGGTCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCA
CCGCGCCAAGCCAAGGTCTGCATTTTTCTTTAGAACTCAGAACACCCAATAGTCCTAGGCCCCCATCCTCGCATGGCAGCAAGCTAAATA
AGCATCTTCCCACTGCGAGTTGGGGCATGACCCAGCCTATGGTTTGCCATACTCCCTCTTTTTCTCCGTTTTTTCATTAATTGTGAACCT
GACCTGCATCACCCTTTCATGTCAGTGCTCTCCAAACCTGCTTGCTTGCACCCCTCTAGTCGAAATATTTTGTGCTTACCCCAATATATG
TGTGTGACTATTGAACTCTATTCGTAGACTGCTTGTACTAATGTCATTTGCATCATAAAATATTCATATCCAATAAACATATTAAAAGGA
TGAGATAAGAAACCGAGAGATTTTGCTGTTTTTTTCCTTTTGCATGGATGAGCCAGCTTCACTGTCCTGGGTGGGGCCCAGGTGGAATTA
GTTCTCAAAGTCCTCCAGGTGGAGTCAGGGAATGTGCAACAGGGTTGGAGAAATCACTACTTTAAGTGAATCCGAAAGGTGAGATCACAT
TTGCTCTAAAGAAATGGTGATCCCAGCACTTTGGGAGGCTGAGGCAGCAGATCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACA
CGGTGAAACCCCGTCTCTACTGAAAACACAAAAATTAGCTGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCA
GGCAAATCGCTTGGCCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCCACGGAGCGAGAGAAGAAA
GAAATGGTGACTTTCATTGATCATGTGTTTGAGGATTTCATGTGCTCTCCAGGGAGGTTTCAGGTGGGTAGAAGGAGGTGGGCAAGACCC
AATAAAAAAGCAGCTGGTGCGGGCAATGACAATGAACTCGTATCCTGCAGGGTCAAAGGAAGGCTTGCTTCTGCTGTGAATTGGAGAAGG
ACTTTCCTGGAAGCACAGGCCCAGAAATCGCACCCTTCTCCCCATGTGTGCGGATAAGGGACCACTTCCATCAGCAGCAGCCCCCTCCTG
CTTTCCTGCCAGTCCTCCCTGTGGTCCCAGGTCTCTTGAGAAAAGTGATCTAAGAGATCCCTTTGCAATGAGGTGCTACTGACTGCCCTA
CCTCCCTCCCTTCCTCCCATGAATGTTTCTTGGTGCTGACCACAGCCTCAGCAATGAGGCAAGCCTGGGGACCCAAGACAGATCTCTGCC
TCCCAGGCTAGTGGATGCCCTGGGATATGTAGTCACCAAAATAGGAACTTACCCCATAGTGGGGAAATAGACAGTAAGCAGCAAATCAAT
AACAAGAGTGTTCCAGATGGTTGTAAGTGCCAGGAAGGGAACCAACTGGGAGAGGGACAAGAGGAGATGGTGACTGACCAAGGGGACCTT
GATCAGGCTGTGGGGAAGGGAGGTGGTTGGGAAGAGCTTCCCAGGAAAGGGGACGGCGGGCCCAGGCAGGAGAGCCTTGGGAGGGGGTGC
CCAAGGAAGGAAAAGGGCCCTGAGCCTGAAGCCGAGAAGACCAGGAGGGGAGAAGGGGAGATGTAGGGCAGAGCAGACGGGAGCCGCTCG
GGTTTTATTCCACACACCCCAGGAAGCATGAGAGGGTTTCAAGCAGCAAGGGCATGGAAGTAACTTGGTGAGATATTTTTATGCATTAGA
TCATCGCTCTATCTGGATTCCAGAGGGTCTCTGAGAGAGCAAACAGCTTAATCCAAAGGAGCGGCTTTCCAACTGGGAATGTCCCCCTGG
CTGGGTGAGATCTCAAGATGGCCTGCGGCCCCTCTAGATTGCCTGCCTACAGAGTTCACTCTAAACAGCCCCTCCCCTCCACACCCCAGC
AGATCCATTCCTGACGCCCTCACTGGCAGGCTCCAGCCCCACAGAGCTTTCTAGACATAAAAGAGCAGGGTCATGGCATCATTGGTGACA
CAATTTTAGTAATAAGCTTCAAAACCCATCACTCCACTGAATCCAGGGATGCCAGAATTGAGAGTCCATAGGACCCGTTTAACGGATCCC
ACATTCAGTAGACGGTTTTTTGTATGCTTCGAGGGAAGGAAGGTATTTTCAAATGCAACTTCTTTTTTTTTTTTCTTGCTCTAGTTAGGG
CTGATTTTACCACTGGGCAAATTGCATACATTTGGATCCATGCCACGCTAAAAACTGTTTATTTTGGAGATCTGTCAGAGGCAAGCACAT
GGAAGACAAGGGGATTCTGGTTTGAAAAGGCAATTCTCATCCAGACAGATTCAGATGGAGAGGAGCGGTGTGGATTAAAATGCGCCGAAG
TGGTAATGCCGTTTATCCCGTTTGCCTTTGTTACTCTGTGATTAAATGGTATTTTTAATTAAGTTTCATTGGGAGCCATAGGTATCGCGG
TGGTGAAATCAATTTGACAACCATAAAGGGGAGAGACGGCACAGGCGTGTTGTGATGATTGCGGCTGTAGGGAAAGCCGGGCAGCTTGCA
GAGGATGGGTGGGAGGAGGGGAAGCCGGCTAAGAATGACTTCCTGCAAGACAGCAAGGGCACCCCTGGGCCACTGCTGTGTTTGGGAGGC
AGGTTTTGGGGGTTGTCAGAAGGCATTCACCTGGTTCTCTCGCTCACCTGAGACACCCGATAGATTCCTGGAAACTCCAGGAAAGTATCT
GAAGATCTGGTTCTCCATTCTCTCTTATTAACAAGGAGAACCACAAGTGCCCCCCAGATCCCGGCTAGAAGGACCAGACAGCTTTCCACC
CCGGTTCCCAGGCAGCCCTGCTCCCATAGTCCTGTGTCCCATCGGCCCCATGCTCCCAGGACAGTCCTAATTCCCACCTCTCAGAACCTT
GTCAGCCAAGTTCTTCCTGCTCTCTGGCCCAAATCCTCCTCCTACATTGGAAACTGAGCCTCTCTGCATCCTCTGCTCTTTCTATCCCGC
TGTCATTCATCAGATTTTCCAAATCTTTGGATTCCTGAGTGGCAGAAGAGGTTTTCTGAGTTTAAGTTCTGATTCTGTGTGTGATTCTCA
CTCTACCACCTCTTCAAACCTTTGTTGTCTTATCTACAAAATAGAATAGTAGTAATCCATCACCTAAGGTTGTTGTGAAGGTTCAATAAG
TTAATGCGTATTTAAAATGCCTCCCACAGTACCTGACATATACTGGGCTTCAGTGAGGTACTAGCTATTATTATTAACCAAGTTTCCTGT
GGTAACAGTTGTAGCTTTGTGACTGGGCCAAATCACTTAACCCCTCTGCGCTCCAGTCTTTGTTTCTATAATGGGGATGATGATAATGCC
TAGCTCATTGGATTGTTCTGTCCCCTACGATCAGCCATGTTAAGTGATTCATATCATGTCTGGTACTTAAAAATCACGCCACGCATGTAC
ATTATTATGATGAAAAATATGATCCGTGATATCCTGACCAAAATATTAAAGGGACTAAAGATAGCTGTGGCTTGTTCAAGAAGAATATTG
TGTCACTATCCCATATATTATCCCATTTGCTCTTCACAGCTTCCATTTTTCGCTAGGCGGATGGCATGGAACTTTTTATAAATGAGATAT
TATGAAAAATGATGTTTTAGGACTCTCATTTCTACAGTGGGAGTAGGTCACCCATTGCAATTTTGGATTTGCTTAAAAAAATTCTTGCCA
TCACCTTCTAATGGATGATCTGTGTACAACAATTGTTTATTGACTCTGAATGTCTAAGTACCAGGGTCAGTCTATTTCAAGGGGAGGGAA
GCATTAATTAACCTCCAGCATTAGATTCAGTGATTCTTTTCCAATGATGCAGTTCATGACTTTGCTCGCATTTACTTTTCATCAATCCTG
AAAGAATTGAGGTAAAATAGTTCCTCTGCACATGTGTGTCAAGCTAAATGGATAACAGCAGATACAGATCTGTTTGCCTGTCTGCACTTG
CCTTTAGACAAAATTCATCAATTTTACAAAAGCCACTGACTAAACATGGCACCAATACAAATGAAGCACTTCTAGCAGGCGGAGATTCCC
TTTGTTTCTGATCTGGTAAATGCGGTAGTTTCCTGCTGAGAGATGGGAAGTGCTGGCCTAGGACAGCAAGGTGCCCTACAGGTGGGGCCA
AAAGGGTCAAGACCGTTCTACAGGAAGTTTAGGAGAAGTTCAATGGTTCCAGATCCTGTGTGCTTCGGGTAATTCTGACCCTCTTCATTA
GTGATAATGGCATGAAGCTCTTTCACACAGTCTTTTTTTTTTTTCTTTTTTTTTTTCAGACAGGGTCTCACCCTGTCACGTAGGCTGGAG
TGCAGTGGTGAGATCACGGCTCACTGCAGCCTCGACTTCATGGGCTCAAGCGATTCTCCTGCCTCAGCCTCCTAAGTAGTCGGGATCATA
GGCACTTGCCACCACATCCGGCTAATTTTTTTGTAGAGACAGGATTTCACCACATTACACAGGCTGGTTTCAAACTCCGAGGCTCAAGTG
ATCTGCCTGCATCGGCCTCCCAAAGCGCTGAGATTACAAGCGTGAGCCACTACGCCTTGCCCTCCACACAGCCTTGCTTGGTGTTAAAGA
TTAAACAAAGACCACAGGTGATCACTGTCTTCGTGGTGCCAGTTTCAAGGGCACCCTTCTTCCCTTCCCAGCCTCCGAGAGAAGGAGAGA
GGGTCCACAAGCCAGATCCATCCCCATCCACACAGGTAAAACCACGACTGTGCAGCTAGCAGGTGGAGATAACATTTGGAAAAAGGCTTT
GTAAATGCTAAAGTCCTACTCAAGTCCAAGGGAGAGAAATTATTATTATTCGTTTTGTGAAACCAATTTAGTTTGGCTGGGTAATGGAAG
AATTTCTACATACATTCATTACTTCTGATCAGGCAAGACCAGTCTGACACAGGAACAGTCTATGGCTCACTCTTAAAGCCACAGCAGGCT
GCCAGGGCTTGGAGAAATAGAAACCTCTCTTGCACAAGAATAGTCTCAATGAATCATGTTAAGGCCTCTTTAGGTTTTTCAGACTCCATG
CACCCTGTGGAAACTGCCTTTCTTGAGTAGAGGTACGTTCAGCACTTCATAAAATAATCTTGGAGCCTCCAGACACACGGATGGAGGAGC
ATGATTTCATTTGTTTCTTTGCAAAACTGCTGTCCCCAACTGAAAAACCTGATTATCCTTTCAAATAGGGAATTCGGCTTTCCACGTTGG
AACCAGAACAGTTAACCTTCAAACCCCCAAGGCTTGCAAGAGATGAATCAGTTTCTCAGACAGCCAAAGCCGTGGCTTATAACTCATCCA
ACCCAGAAAACTGGACCGCTGGTCACCTTCCTTCCCCCTGCCCCCAACTCTGCAGACAGAGGTTTCCCGTTGATTATGCCTTGATTAGAG
TCAGGAGAGAAGCAAACCAGGTATATAGGATTCCATTATCCTTCCCTCCTCTGCTCCCAACCAGGGTCACGCTGAGAGGGATCTCGGTGA
ACATGTGAACAATCAAGCCATGTTTACCATGGACGTTTAGTTTTCTTTTCTCAAAATCAAAACAGAGTTTAGTAGGCAGCGTATTTCATA
CATGCCCCTTGATCAATGGAATGATCTGTCAGAAGCCATTAAAGCCCCCATTAGCTTGAATGCATTCAAAGCTAAACTATTGGATCATTT
AAGGGCTGCAGTGATTGTTTTTAATATACCGTACATTGATTTCTCCCTGTGAGCAGCAACATAAGTTTGAAACTAACTGTGTATGACTAA
GGCTCCATTTGCTGTCTCCAACCCTCTGTGAGAAGCATGGTTTCACTTCGACCAGAAATGTCTGTGTATAGTTTTCAAAGAGATGCAGAC
CCTGTTCGATTTCCCAAGATTTAGACTGGGTCGGGTTGTTATTTCTTTTTTCCCTGAGCTTTCTCCCATTTCTTTGTGCCCATTAAGTGA
GCTGTGCGTGCAGAATGGGAGAGGCATCCCTGCCAAGGACTTCAAGTGAAAGGCGGTGGGAGAAATTGTTCTGAAAGCATGAAGCCCAGC
TGAGGCCAAAATCAAAGTGAATTTGACAGCCTTGGGCCAGCAAAACTCTGTACCCAGCAGAAAACAATAGATGTGTGGCTGTGTCAGGGG
CATCCTCACTGGGACATAGCTTGGGGAGCTGAAGGTACCTTGGAAGGGCCAGATGAGGAAGCTAGCCAAGGCCACAGGCCTTCCTTTGAC
TGCCATATTGCCAGCTCTTCATAGTATTGACTCTTCAGTCTTAGCCAACACACACTTGTTGATTCCTTCCGGAATGTCAGACTCTGCTAG
CAACACAAGGTCCCTGTCCTCAAAATCCTATTCTTAATCAGCATTTCTAATTTCTGCCCTTTGCTCATTTTAATACAGAGCCTGAGGATA
GGAGAGCAGCGTGGTGAAAGAAGCAATAGTTACCACATTTGCAAAGGCACATACCCCAAAGAGAAGTTTTTAATATGTCACACCCATATT
TTATAGATGGGGCAATGGAAGTCCAGATGGGAGAAGTTATTTCAGGTGAATTATAGAAACTGGATTTCAAGTTTCTGATAAGTATTGAAT
TTGGGAAGGCTGTGAACATTCTTGAGCCCCCCTCCCAAGTTCACCTTCAACATCCTAAAGCAGGTTGAAGAGGAAGATGGTTCCAGGTCA
CTTACAAGAACAGGAACAGCCCCTCCCTCCAAATTTGAGCCCAGAAAGGAGAACCTTTGTTACTCTAGAAAACAGTGTGTGTGCTATTGT
TTTCTCCATAGGTCACAAACATCCACAAGATATTGGTGATTTTACATATTATTAGAGCCACTGAAATTTATGATGCAGGATATTAACGTC
AAAGAGGCCAAGATGCATCATTCAGAACACTGGCAGGTCAAGCAGAAACCACCGTAGTAAAATTGAAAGCTGGAGTCAGCAAAGTATAGC
CCACAGCCAAATCTGGCCCATCCCCTGTTCTTATAAAGTTTTATTGGAACGCAGCCATGCTCATCGGTTTATGTATTATCTATGGCTGTT
TCCAACTACAGTGGCAGAGCTGAATAGTTGCAAAGGACCATAGGGCTATCAAAGCCCCAAATAGTCATTGTCTGACCCTTCATAGAAAAA
TTTTGCTGAACTGTAGTCTAGCTCCAAGGATTGTTGTATCACCTGTGATCGTGCCTATTAAGCAATTAACGTCATGTCTAGTACTTAGTA
ATGACTCAGCATGTATCAATTACGATGATAAATATTATCATGGCATCCAAACCAAAATACTCATGCCAACATCTCTCTGTACAGAAACAT
GGAAAAAGAGCGATGCTATTAAGGAGGAAAATGGAGCCAGGAGCAAAACCTAAGGCTATTTCTGAACTAAAGAGGCCTGAATAAGGTAGT
GAAAGGACCAGGGAAAGCCTTCCCACGGGGATGGAGAGCCACCTCCTCCCCGGCTTTCTGGTTCAGATGTCTTGTCTCAACAGACGGCAG
ATTCGCAGGGAAGCAGGCCGAGCCTGATCTTTTCTCCGCTAGAACTGCTCAACAGGTGAAGAATCTTTTTCCAGCACTCCTGAGCCCTTC
GGGTCGCGGAACAGTGCGAAGATTATTCCAATGCCTCATTCGGAGAGGTGATAATCTGGTCTGTGGTTTCTTTTTCGGTGGGGCATGGGG
TGGGGGTGAGTGTCATGCTTTCTAAGGCACAGGGCTGACTAAAGGGTGTCCTATTTATAAGTCAGTAAAACACAGCGGCTTCATACTCTG
TGCTTATTACCCAGAAGCCCCGGCTCTTAGAGTTTCTATTAAGATGTACCTCATAAATATATACGCCTCCTATGTACCCACAAAAATTAA

>1777_1777_9_ACTN4-FTO_ACTN4_chr19_39138547_ENST00000424234_FTO_chr16_53844052_ENST00000471389_length(amino acids)=544AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLIL
REASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLK
LNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWH
HDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTH
RVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME
GVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACTN4-FTO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+11412_2654.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+11412_2654.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+11412_2654.0693.0VCL


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138546chr16:53844051ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138546chr16:53844051ENST00000390009+11440_6154.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844051ENST00000390009+11440_6154.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138547chr16:53844052ENST00000390009+11440_6154.0693.0VCL


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACTN4-FTO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACTN4-FTO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource