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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:COBL-SEPT14 (FusionGDB2 ID:17986)

Fusion Gene Summary for COBL-SEPT14

check button Fusion gene summary
Fusion gene informationFusion gene name: COBL-SEPT14
Fusion gene ID: 17986
HgeneTgene
Gene symbol

COBL

SEPT14

Gene ID

23242

346288

Gene namecordon-bleu WH2 repeat proteinseptin 14
Synonyms-SEPT14
Cytomap

7p12.1

7p11.2

Type of geneprotein-codingprotein-coding
Descriptionprotein cordon-bleuseptin-14
Modification date2020031320200313
UniProtAcc

O75128

.
Ensembl transtripts involved in fusion geneENST00000265136, ENST00000395540, 
ENST00000395542, ENST00000441453, 
ENST00000477628, ENST00000388975, 
Fusion gene scores* DoF score5 X 7 X 5=1756 X 5 X 5=150
# samples 713
** MAII scorelog2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/150*10)=-0.206450877467426
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: COBL [Title/Abstract] AND SEPT14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCOBL(51203855)-SEPT14(55886916), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across COBL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SEPT14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-CU-A0YN-01ACOBLchr7

51150755

-SEPT14chr7

55874951

-
ChimerDB4GBMTCGA-28-5208-01ACOBLchr7

51203855

-SEPT14chr7

55886916

-
ChimerDB4GBMTCGA-28-5208COBLchr7

51203854

-SEPT14chr7

55886916

-


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Fusion Gene ORF analysis for COBL-SEPT14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265136ENST00000477628COBLchr7

51203855

-SEPT14chr7

55886916

-
5CDS-intronENST00000265136ENST00000477628COBLchr7

51203854

-SEPT14chr7

55886916

-
5CDS-intronENST00000395540ENST00000477628COBLchr7

51203855

-SEPT14chr7

55886916

-
5CDS-intronENST00000395540ENST00000477628COBLchr7

51203854

-SEPT14chr7

55886916

-
5CDS-intronENST00000395542ENST00000477628COBLchr7

51150755

-SEPT14chr7

55874951

-
5CDS-intronENST00000395542ENST00000477628COBLchr7

51203855

-SEPT14chr7

55886916

-
5CDS-intronENST00000395542ENST00000477628COBLchr7

51203854

-SEPT14chr7

55886916

-
5CDS-intronENST00000441453ENST00000477628COBLchr7

51203855

-SEPT14chr7

55886916

-
5CDS-intronENST00000441453ENST00000477628COBLchr7

51203854

-SEPT14chr7

55886916

-
In-frameENST00000265136ENST00000388975COBLchr7

51203855

-SEPT14chr7

55886916

-
In-frameENST00000265136ENST00000388975COBLchr7

51203854

-SEPT14chr7

55886916

-
In-frameENST00000395540ENST00000388975COBLchr7

51203855

-SEPT14chr7

55886916

-
In-frameENST00000395540ENST00000388975COBLchr7

51203854

-SEPT14chr7

55886916

-
In-frameENST00000395542ENST00000388975COBLchr7

51150755

-SEPT14chr7

55874951

-
In-frameENST00000395542ENST00000388975COBLchr7

51203855

-SEPT14chr7

55886916

-
In-frameENST00000395542ENST00000388975COBLchr7

51203854

-SEPT14chr7

55886916

-
In-frameENST00000441453ENST00000388975COBLchr7

51203855

-SEPT14chr7

55886916

-
In-frameENST00000441453ENST00000388975COBLchr7

51203854

-SEPT14chr7

55886916

-
intron-3CDSENST00000265136ENST00000388975COBLchr7

51150755

-SEPT14chr7

55874951

-
intron-3CDSENST00000395540ENST00000388975COBLchr7

51150755

-SEPT14chr7

55874951

-
intron-3CDSENST00000441453ENST00000388975COBLchr7

51150755

-SEPT14chr7

55874951

-
intron-intronENST00000265136ENST00000477628COBLchr7

51150755

-SEPT14chr7

55874951

-
intron-intronENST00000395540ENST00000477628COBLchr7

51150755

-SEPT14chr7

55874951

-
intron-intronENST00000441453ENST00000477628COBLchr7

51150755

-SEPT14chr7

55874951

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000395542COBLchr751150755-ENST00000388975SEPT14chr755874951-437815271372008623
ENST00000265136COBLchr751203855-ENST00000388975SEPT14chr755886916-407111231181701527
ENST00000395542COBLchr751203855-ENST00000388975SEPT14chr755886916-416512171371795552
ENST00000395540COBLchr751203855-ENST00000388975SEPT14chr755886916-409011421371720527
ENST00000441453COBLchr751203855-ENST00000388975SEPT14chr755886916-40361088831666527
ENST00000265136COBLchr751203854-ENST00000388975SEPT14chr755886916-407111231181701527
ENST00000395542COBLchr751203854-ENST00000388975SEPT14chr755886916-416512171371795552
ENST00000395540COBLchr751203854-ENST00000388975SEPT14chr755886916-409011421371720527
ENST00000441453COBLchr751203854-ENST00000388975SEPT14chr755886916-40361088831666527

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000395542ENST00000388975COBLchr751150755-SEPT14chr755874951-0.000343150.9996568
ENST00000265136ENST00000388975COBLchr751203855-SEPT14chr755886916-0.0003017150.9996983
ENST00000395542ENST00000388975COBLchr751203855-SEPT14chr755886916-0.0003252890.9996747
ENST00000395540ENST00000388975COBLchr751203855-SEPT14chr755886916-0.000304570.9996954
ENST00000441453ENST00000388975COBLchr751203855-SEPT14chr755886916-0.0002973940.99970263
ENST00000265136ENST00000388975COBLchr751203854-SEPT14chr755886916-0.0003017150.9996983
ENST00000395542ENST00000388975COBLchr751203854-SEPT14chr755886916-0.0003252890.9996747
ENST00000395540ENST00000388975COBLchr751203854-SEPT14chr755886916-0.000304570.9996954
ENST00000441453ENST00000388975COBLchr751203854-SEPT14chr755886916-0.0002973940.99970263

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Fusion Genomic Features for COBL-SEPT14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for COBL-SEPT14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:51203855/chr7:55886916)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
COBL

O75128

.
FUNCTION: Plays an important role in the reorganization of the actin cytoskeleton. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells (By similarity). Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. {ECO:0000250, ECO:0000269|PubMed:21816349}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-91522_254471344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-915303_3514471344.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-61322_253191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-6822_25319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-71522_253441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-6822_25319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-61322_253191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-6822_25319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-71522_253441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-6822_25319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-915298_3034471344.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-915331_3364471344.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-613298_3033191262.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-68298_303319470.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-715298_3033441344.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-715331_3363441344.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-68298_303319380.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-613298_3033191262.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-68298_303319470.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-715298_3033441344.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-715331_3363441344.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-68298_303319380.0MotifNote=KKRRAP 1
TgeneSEPT14chr7:51150755chr7:55874951ENST00000388975610332_412272433.0Coiled coilOntology_term=ECO:0000255
TgeneSEPT14chr7:51203854chr7:55886916ENST00000388975510332_412240433.0Coiled coilOntology_term=ECO:0000255
TgeneSEPT14chr7:51203855chr7:55886916ENST00000388975510332_412240433.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-1131021_102401262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-1131207_121301262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-11322_2501262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-113303_35101262.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-181021_10240470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-181207_12130470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-1822_250470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-18303_3510470.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-9151021_10244471344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-9151207_12134471344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-181021_10240380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-181207_12130380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-1822_250380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-18303_3510380.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-6131021_10243191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-6131207_12133191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-613303_3513191262.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-681021_1024319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-681207_1213319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-68303_351319470.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-7151021_10243441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-7151207_12133441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-715303_3513441344.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-681021_1024319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-681207_1213319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-68303_351319380.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-6131021_10243191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-6131207_12133191262.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-613303_3513191262.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-681021_1024319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-681207_1213319470.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-68303_351319470.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-7151021_10243441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-7151207_12133441344.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-715303_3513441344.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-681021_1024319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-681207_1213319380.0Compositional biasNote=Poly-Pro
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-68303_351319380.0Compositional biasNote=Pro-rich
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-1131109_112901262.0DomainWH2 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-1131149_116901262.0DomainWH2 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-1131237_125701262.0DomainWH2 3
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-181109_11290470.0DomainWH2 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-181149_11690470.0DomainWH2 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-181237_12570470.0DomainWH2 3
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-9151109_11294471344.0DomainWH2 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-9151149_11694471344.0DomainWH2 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000395542-9151237_12574471344.0DomainWH2 3
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-181109_11290380.0DomainWH2 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-181149_11690380.0DomainWH2 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-181237_12570380.0DomainWH2 3
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-6131109_11293191262.0DomainWH2 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-6131149_11693191262.0DomainWH2 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-6131237_12573191262.0DomainWH2 3
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-681109_1129319470.0DomainWH2 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-681149_1169319470.0DomainWH2 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-681237_1257319470.0DomainWH2 3
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-7151109_11293441344.0DomainWH2 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-7151149_11693441344.0DomainWH2 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000395542-7151237_12573441344.0DomainWH2 3
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-681109_1129319380.0DomainWH2 1
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-681149_1169319380.0DomainWH2 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-681237_1257319380.0DomainWH2 3
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-6131109_11293191262.0DomainWH2 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-6131149_11693191262.0DomainWH2 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-6131237_12573191262.0DomainWH2 3
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-681109_1129319470.0DomainWH2 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-681149_1169319470.0DomainWH2 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-681237_1257319470.0DomainWH2 3
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-7151109_11293441344.0DomainWH2 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-7151149_11693441344.0DomainWH2 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000395542-7151237_12573441344.0DomainWH2 3
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-681109_1129319380.0DomainWH2 1
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-681149_1169319380.0DomainWH2 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-681237_1257319380.0DomainWH2 3
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-113298_30301262.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000265136-113331_33601262.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-18298_3030470.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000395540-18331_3360470.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-18298_3030380.0MotifNote=KKRRAP 1
HgeneCOBLchr7:51150755chr7:55874951ENST00000441453-18331_3360380.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000265136-613331_3363191262.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000395540-68331_336319470.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203854chr7:55886916ENST00000441453-68331_336319380.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000265136-613331_3363191262.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000395540-68331_336319470.0MotifNote=KKRRAP 2
HgeneCOBLchr7:51203855chr7:55886916ENST00000441453-68331_336319380.0MotifNote=KKRRAP 2
TgeneSEPT14chr7:51150755chr7:55874951ENST0000038897561049_315272433.0DomainSeptin-type G
TgeneSEPT14chr7:51203854chr7:55886916ENST0000038897551049_315240433.0DomainSeptin-type G
TgeneSEPT14chr7:51203855chr7:55886916ENST0000038897551049_315240433.0DomainSeptin-type G
TgeneSEPT14chr7:51150755chr7:55874951ENST00000388975610195_203272433.0Nucleotide bindingGTP
TgeneSEPT14chr7:51203854chr7:55886916ENST00000388975510195_203240433.0Nucleotide bindingGTP
TgeneSEPT14chr7:51203855chr7:55886916ENST00000388975510195_203240433.0Nucleotide bindingGTP
TgeneSEPT14chr7:51150755chr7:55874951ENST00000388975610111_114272433.0RegionG3 motif
TgeneSEPT14chr7:51150755chr7:55874951ENST00000388975610194_197272433.0RegionG4 motif
TgeneSEPT14chr7:51150755chr7:55874951ENST0000038897561059_66272433.0RegionG1 motif
TgeneSEPT14chr7:51203854chr7:55886916ENST00000388975510111_114240433.0RegionG3 motif
TgeneSEPT14chr7:51203854chr7:55886916ENST00000388975510194_197240433.0RegionG4 motif
TgeneSEPT14chr7:51203854chr7:55886916ENST0000038897551059_66240433.0RegionG1 motif
TgeneSEPT14chr7:51203855chr7:55886916ENST00000388975510111_114240433.0RegionG3 motif
TgeneSEPT14chr7:51203855chr7:55886916ENST00000388975510194_197240433.0RegionG4 motif
TgeneSEPT14chr7:51203855chr7:55886916ENST0000038897551059_66240433.0RegionG1 motif


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Fusion Gene Sequence for COBL-SEPT14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17986_17986_1_COBL-SEPT14_COBL_chr7_51150755_ENST00000395542_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=4378nt_BP=1527nt
CCGCCCGCTAGAGACGATTCCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCG
CGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCG
GCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTG
CCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGA
GGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTAC
TGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTA
AGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTA
AGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGA
ATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGC
TGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATG
ATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGCTGAGCAGCTCGTGCTGTCGG
GTGCAGACAGCGATGAGGACACCTCCAGGGCTGCCCCAGGAAGGGGTTTGAACGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACT
CACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTC
CTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGTATCTCTTGGGTCACAGATTGATTTACAGAAGAAGAAGCGGC
GAGCGCCAGCTCCCCCTCCACCACAGCCACCACCACCGAGTCCCCTGATCCCCAACCGCACTGAGGATAAGGAGGAGAACAGGAAGAGCA
CGATGGGTGGTGGACGGCAGGTGCCACAAAAGCCTCCCAGAGGCACTGCTCGGGGTCCACCCCAGTTAGTGCTTCCCCCACCCCCGCCCT
ACCCTCCTCCCGACACAGACGTGGTGGAGCCTCTCAGCTTTCCCGGGGAAGGCGCTGGTTCCGAGGCCTCAGACCCGATACCCAAACTGG
AAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGC
ACTATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCT
TTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAG
AAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGG
AAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATA
CAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGT
CTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGG
GTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCA
AAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAG
GCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACT
CCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTT
AGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCT
GGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTT
TGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTC
TTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTC
AAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATA
AGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGC
CCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAA
AGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGC
GCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATT
TGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCT
AGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACA
TTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGAC
CTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCT
ACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAG
GATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTC
CATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCA
TGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACT
TCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTT
TGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAAT
TCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATT

>17986_17986_1_COBL-SEPT14_COBL_chr7_51150755_ENST00000395542_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=623AA_BP=464
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKAEQLVLSGADSDEDTSRAAPGRGLNGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEK
VSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMGGGRQVPQKPPRGTARGPPQLVLPPPPPYPPPDTDVVEPLSFPG
EGAGSEASDPIPKLENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREE

--------------------------------------------------------------
>17986_17986_2_COBL-SEPT14_COBL_chr7_51203854_ENST00000265136_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4071nt_BP=1123nt
CCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCGCGGAAAAAGTGAATGAGGG
CGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCGGCACCATGGACGCGCCGCG
CGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTGCCACTCTGCATGTGCACAG
TGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGAGGGCCAGCACCATGGACGT
CACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTACTGGTTGAACTTTGCCTTCA
GAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTAAGCCAAATACTTTGATTGG
GACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTAAGGTGCCTGAGAAATCTGT
GCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGAATATTCTCCCAGTCATTTG
TGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGCTGTCCAAGTCCCTGAACGA
GCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATGATGAGACAGATAAAGAGAA
GAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACTCACG
TTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTCCTCC
TCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGT
TGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGA
TATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAAT
GGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCA
GAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGA
CAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTT
TTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCT
CTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAA
ATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGG
AGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAA
TTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGC
AGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAAC
TCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAAT
ATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTT
TTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATAC
AAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAA
GAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATAT
TATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAAT
ACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAG
AGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTG
ACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATG
GAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTAT
TCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTA
ATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTA
TTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAAT
AGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCC
AAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCC
ATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAA
GTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAG
TTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTT
ATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTG
ATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAAATCCTGTAGAAAA

>17986_17986_2_COBL-SEPT14_COBL_chr7_51203854_ENST00000265136_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------
>17986_17986_3_COBL-SEPT14_COBL_chr7_51203854_ENST00000395540_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4090nt_BP=1142nt
CCGCCCGCTAGAGACGATTCCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCG
CGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCG
GCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTG
CCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGA
GGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTAC
TGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTA
AGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTA
AGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGA
ATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGC
TGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATG
ATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACT
CCCCATCCATGCACTCACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGA
AGCGCCGAGCCCCTCCTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGA
GTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTG
ACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGT
ACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAG
AGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAG
CTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGG
AAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATC
GTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTC
TGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCT
GTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCC
TCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAA
CCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAA
AAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACA
AATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTT
ATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGC
ATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATA
AAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGT
TGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCT
CACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAA
CCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATC
GCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTG
GTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTT
ACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCT
GACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATT
GACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTT
TCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCA
TTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAAC
ATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAA
AAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCA
GATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGA
TTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTA
CATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTC
TACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTC

>17986_17986_3_COBL-SEPT14_COBL_chr7_51203854_ENST00000395540_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------
>17986_17986_4_COBL-SEPT14_COBL_chr7_51203854_ENST00000395542_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4165nt_BP=1217nt
CCGCCCGCTAGAGACGATTCCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCG
CGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCG
GCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTG
CCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGA
GGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTAC
TGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTA
AGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTA
AGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGA
ATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGC
TGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATG
ATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGCTGAGCAGCTCGTGCTGTCGG
GTGCAGACAGCGATGAGGACACCTCCAGGGCTGCCCCAGGAAGGGGTTTGAACGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACT
CACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTC
CTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGA
AAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCC
GAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGA
AAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAAT
GTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGC
AGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAG
ATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGT
TTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTT
AAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTT
TGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACA
AAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGG
TTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTAT
GAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAAT
CAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCT
GCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTT
ATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTG
ATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATA
ATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCC
AGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAA
TAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAG
GCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTG
CCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTT
AATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAA
TTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATA
ATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAAT
GTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGA
GAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATT
TTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTT
TTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATG
GAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGA
CAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGG
AGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTT
ATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAAATCCTGTAG

>17986_17986_4_COBL-SEPT14_COBL_chr7_51203854_ENST00000395542_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=552AA_BP=360
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKAEQLVLSGADSDEDTSRAAPGRGLNGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEK
GLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSF
QEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQL

--------------------------------------------------------------
>17986_17986_5_COBL-SEPT14_COBL_chr7_51203854_ENST00000441453_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4036nt_BP=1088nt
CTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCGCGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTC
GGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCGGCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGA
TGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTGCCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGT
CGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGAGGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGA
GCGTGCTCAATGGGAGCCATGCGATGATGGACCTACTGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAA
TTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTAAGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAA
AAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTAAGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAG
CTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGAATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTC
TCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGCTGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACA
GAAGAGAAACCTTTAGGAAATCATCACTTGGCAATGATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAA
GAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACTCACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCA
GCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTCCTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCAT
CGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTT
GGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAG
AAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAG
TTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGC
AGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGG
AGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGA
CTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGC
AACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAA
GTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGT
TCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCA
GCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTG
GGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGA
TTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAG
CATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCA
AATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGT
TCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGA
TATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTA
TCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGT
CAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGT
AGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTC
CAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCAT
CTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTC
ACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAG
CTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGA
GTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCA
TATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGG
TTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATA
AGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCT
CTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCA
TTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATT
CTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACT
TCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCA

>17986_17986_5_COBL-SEPT14_COBL_chr7_51203854_ENST00000441453_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------
>17986_17986_6_COBL-SEPT14_COBL_chr7_51203855_ENST00000265136_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4071nt_BP=1123nt
CCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCGCGGAAAAAGTGAATGAGGG
CGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCGGCACCATGGACGCGCCGCG
CGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTGCCACTCTGCATGTGCACAG
TGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGAGGGCCAGCACCATGGACGT
CACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTACTGGTTGAACTTTGCCTTCA
GAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTAAGCCAAATACTTTGATTGG
GACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTAAGGTGCCTGAGAAATCTGT
GCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGAATATTCTCCCAGTCATTTG
TGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGCTGTCCAAGTCCCTGAACGA
GCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATGATGAGACAGATAAAGAGAA
GAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACTCACG
TTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTCCTCC
TCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGT
TGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGA
TATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAAT
GGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCA
GAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGA
CAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTT
TTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCT
CTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAA
ATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGG
AGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAA
TTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGC
AGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAAC
TCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAAT
ATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTT
TTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATAC
AAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAA
GAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATAT
TATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAAT
ACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAG
AGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTG
ACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATG
GAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTAT
TCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTA
ATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTA
TTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAAT
AGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCC
AAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCC
ATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAA
GTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAG
TTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTT
ATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTG
ATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAAATCCTGTAGAAAA

>17986_17986_6_COBL-SEPT14_COBL_chr7_51203855_ENST00000265136_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------
>17986_17986_7_COBL-SEPT14_COBL_chr7_51203855_ENST00000395540_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4090nt_BP=1142nt
CCGCCCGCTAGAGACGATTCCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCG
CGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCG
GCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTG
CCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGA
GGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTAC
TGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTA
AGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTA
AGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGA
ATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGC
TGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATG
ATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACT
CCCCATCCATGCACTCACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGA
AGCGCCGAGCCCCTCCTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGA
GTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTG
ACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGT
ACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAG
AGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAG
CTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGG
AAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATC
GTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTC
TGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCT
GTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCC
TCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAA
CCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAA
AAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACA
AATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTT
ATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGC
ATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATA
AAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGT
TGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCT
CACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAA
CCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATC
GCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTG
GTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTT
ACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCT
GACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATT
GACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTT
TCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCA
TTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAAC
ATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAA
AAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCA
GATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGA
TTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTA
CATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTC
TACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTC

>17986_17986_7_COBL-SEPT14_COBL_chr7_51203855_ENST00000395540_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------
>17986_17986_8_COBL-SEPT14_COBL_chr7_51203855_ENST00000395542_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4165nt_BP=1217nt
CCGCCCGCTAGAGACGATTCCAGCCCCTTCCGTCCGCCGCGCTCCGCCGCTGTCCTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCG
CGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTCGGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCG
GCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGATGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTG
CCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGTCGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGA
GGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGAGCGTGCTCAATGGGAGCCATGCGATGATGGACCTAC
TGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAATTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTA
AGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAAAAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTA
AGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAGCTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGA
ATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTCTCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGC
TGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACAGAAGAGAAACCTTTAGGAAATCATCACTTGGCAATG
ATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAAGAAGCAATAGTAAGGCTGAGCAGCTCGTGCTGTCGG
GTGCAGACAGCGATGAGGACACCTCCAGGGCTGCCCCAGGAAGGGGTTTGAACGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACT
CACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCAGCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTC
CTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCATCGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGA
AAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCC
GAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGA
AAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAAT
GTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGC
AGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAG
ATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGT
TTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTT
AAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTT
TGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACA
AAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGG
TTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTAT
GAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAAT
CAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCT
GCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTT
ATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTG
ATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATA
ATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCC
AGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAA
TAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAG
GCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTG
CCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTT
AATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAA
TTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATA
ATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAAT
GTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGA
GAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATT
TTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTT
TTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATG
GAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGA
CAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGG
AGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTT
ATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAAATCCTGTAG

>17986_17986_8_COBL-SEPT14_COBL_chr7_51203855_ENST00000395542_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=552AA_BP=360
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKAEQLVLSGADSDEDTSRAAPGRGLNGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEK
GLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSF
QEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQL

--------------------------------------------------------------
>17986_17986_9_COBL-SEPT14_COBL_chr7_51203855_ENST00000441453_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=4036nt_BP=1088nt
CTCCGCCGGCCCGCGTGGGAGGACGATGGGTCAGCGCGGAAAAAGTGAATGAGGGCGGCAGCGGTGGCGGCGGTAGCCAGCGCCTGACTC
GGCGGGCCCGGAGCACCGCCCGCGTCCCGGCCCCCGGCACCATGGACGCGCCGCGCGCCTCGGCGGCCAAGCCCCCGACCGGGAGGAAGA
TGAAGGCTCGTGCTCCCCCACCTCCTGGAAAGGCTGCCACTCTGCATGTGCACAGTGACCAGAAGCCCCCCCACGATGGGGCCCTCGGGT
CGCAGCAGAACTTGGTTCGCATGAAGGAGGCGCTGAGGGCCAGCACCATGGACGTCACCGTGGTCCTGCCTAGTGGGCTGGAGAAGAGGA
GCGTGCTCAATGGGAGCCATGCGATGATGGACCTACTGGTTGAACTTTGCCTTCAGAACCACCTGAATCCATCCCACCATGCCCTTGAAA
TTCGGTCTTCAGAAACCCAACAACCTTTGAGTTTTAAGCCAAATACTTTGATTGGGACCCTGAATGTGCATACTGTGTTTCTGAAAGAAA
AAGTTCCTGAAGAGAAGGTTAAGCCTGGTCCCCCTAAGGTGCCTGAGAAATCTGTGCGTTTGGTCGTGAATTACCTGCGGACACAAAAAG
CTGTTGTGCGTGTGAGCCCTGAGGTTCCTCTCCAGAATATTCTCCCAGTCATTTGTGCAAAGTGTGAGGTCAGCCCAGAGCACGTGGTTC
TCCTCAGGGACAACATTGCCGGAGAGGAGCTGGAGCTGTCCAAGTCCCTGAACGAGCTCGGGATAAAGGAGCTCTACGCGTGGGACAACA
GAAGAGAAACCTTTAGGAAATCATCACTTGGCAATGATGAGACAGATAAAGAGAAGAAAAAATTTCTGGGATTTTTCAAAGTTAATAAAA
GAAGCAATAGTAAGGGCTGTTTAACGACCCCCAACTCCCCATCCATGCACTCACGTTCTCTTACGCTGGGTCCATCCCTCTCGCTGGGCA
GCATCTCAGGGGTGTCCGTGAAGTCGGAGATGAAGAAGCGCCGAGCCCCTCCTCCTCCAGGTTCAGGGCCACCTGTGCAAGACAAGGCAT
CGGAAAAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTT
GGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAG
AAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAG
TTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGC
AGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGG
AGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGA
CTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGC
AACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAA
GTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGT
TCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCA
GCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTG
GGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGA
TTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAG
CATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCA
AATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGT
TCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGA
TATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTA
TCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGT
CAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGT
AGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTC
CAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCAT
CTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTC
ACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAG
CTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGA
GTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCA
TATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGG
TTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATA
AGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCT
CTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCA
TTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATT
CTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACT
TCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCA

>17986_17986_9_COBL-SEPT14_COBL_chr7_51203855_ENST00000441453_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=527AA_BP=335
MTRRARSTARVPAPGTMDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLE
KRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRT
QKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKV
NKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKGLLPFAVVGSTDEVKVGKRMVRGRH
YPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for COBL-SEPT14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for COBL-SEPT14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for COBL-SEPT14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource