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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:COG5-DPP6 (FusionGDB2 ID:18020)

Fusion Gene Summary for COG5-DPP6

check button Fusion gene summary
Fusion gene informationFusion gene name: COG5-DPP6
Fusion gene ID: 18020
HgeneTgene
Gene symbol

COG5

DPP6

Gene ID

10466

1804

Gene namecomponent of oligomeric golgi complex 5dipeptidyl peptidase like 6
SynonymsCDG2I|GOLTC1|GTC90DPL1|DPPX|MRD33|VF2
Cytomap

7q22.3

7q36.2

Type of geneprotein-codingprotein-coding
Descriptionconserved oligomeric Golgi complex subunit 513S golgi transport complex 1 90 kDa subunitCOG complex subunit 5conserved oligomeric Golgi complex protein 5dipeptidyl aminopeptidase-like protein 6DPP VIdipeptidyl aminopeptidase IV-related proteindipeptidyl peptidase IV-related proteindipeptidyl peptidase VIdipeptidyl-peptidase 6
Modification date2020031320200313
UniProtAcc

Q9UP83

P42658

Ensembl transtripts involved in fusion geneENST00000297135, ENST00000347053, 
ENST00000393603, ENST00000475638, 
ENST00000332007, ENST00000377770, 
ENST00000406326, ENST00000427557, 
ENST00000496611, ENST00000404039, 
Fusion gene scores* DoF score18 X 12 X 10=216017 X 17 X 7=2023
# samples 1919
** MAII scorelog2(19/2160*10)=-3.50695998871988
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2023*10)=-3.41242499622733
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: COG5 [Title/Abstract] AND DPP6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCOG5(107052947)-DPP6(154519477), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCOG5

GO:0048219

inter-Golgi cisterna vesicle-mediated transport

9792665

TgeneDPP6

GO:1901379

regulation of potassium ion transmembrane transport

18364354


check buttonFusion gene breakpoints across COG5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DPP6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0W7-01ACOG5chr7

107052947

-DPP6chr7

154519477

+


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Fusion Gene ORF analysis for COG5-DPP6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000297135ENST00000332007COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000297135ENST00000377770COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000297135ENST00000406326COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000297135ENST00000427557COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000297135ENST00000496611COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000347053ENST00000332007COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000347053ENST00000377770COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000347053ENST00000406326COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000347053ENST00000427557COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000347053ENST00000496611COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000393603ENST00000332007COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000393603ENST00000377770COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000393603ENST00000406326COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000393603ENST00000427557COG5chr7

107052947

-DPP6chr7

154519477

+
5CDS-intronENST00000393603ENST00000496611COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-3CDSENST00000475638ENST00000404039COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-intronENST00000475638ENST00000332007COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-intronENST00000475638ENST00000377770COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-intronENST00000475638ENST00000406326COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-intronENST00000475638ENST00000427557COG5chr7

107052947

-DPP6chr7

154519477

+
5UTR-intronENST00000475638ENST00000496611COG5chr7

107052947

-DPP6chr7

154519477

+
In-frameENST00000297135ENST00000404039COG5chr7

107052947

-DPP6chr7

154519477

+
In-frameENST00000347053ENST00000404039COG5chr7

107052947

-DPP6chr7

154519477

+
In-frameENST00000393603ENST00000404039COG5chr7

107052947

-DPP6chr7

154519477

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000347053COG5chr7107052947-ENST00000404039DPP6chr7154519477+4454813182648876
ENST00000297135COG5chr7107052947-ENST00000404039DPP6chr7154519477+492812874923122876
ENST00000393603COG5chr7107052947-ENST00000404039DPP6chr7154519477+467510342392869876

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000347053ENST00000404039COG5chr7107052947-DPP6chr7154519477+0.0007053180.99929464
ENST00000297135ENST00000404039COG5chr7107052947-DPP6chr7154519477+0.0007376550.9992624
ENST00000393603ENST00000404039COG5chr7107052947-DPP6chr7154519477+0.0007638690.9992361

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Fusion Genomic Features for COG5-DPP6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
COG5chr7107052946-DPP6chr7154519476+5.05E-081
COG5chr7107052946-DPP6chr7154519476+5.05E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for COG5-DPP6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:107052947/chr7:154519477)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
COG5

Q9UP83

DPP6

P42658

FUNCTION: Required for normal Golgi function. {ECO:0000250}.FUNCTION: Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437, PubMed:19441798). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:18364354). Has no dipeptidyl aminopeptidase activity (PubMed:8103397, PubMed:15476821). {ECO:0000269|PubMed:15454437, ECO:0000269|PubMed:18364354, ECO:0000269|PubMed:8103397, ECO:0000305|PubMed:15476821}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDPP6chr7:107052947chr7:154519477ENST00000332007626117_865192804.0Topological domainExtracellular
TgeneDPP6chr7:107052947chr7:154519477ENST000003320076261_95192804.0Topological domainCytoplasmic
TgeneDPP6chr7:107052947chr7:154519477ENST00000377770626117_865254866.0Topological domainExtracellular
TgeneDPP6chr7:107052947chr7:154519477ENST000003777706261_95254866.0Topological domainCytoplasmic
TgeneDPP6chr7:107052947chr7:154519477ENST0000033200762696_116192804.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneDPP6chr7:107052947chr7:154519477ENST0000037777062696_116254866.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for COG5-DPP6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>18020_18020_1_COG5-DPP6_COG5_chr7_107052947_ENST00000297135_DPP6_chr7_154519477_ENST00000404039_length(transcript)=4928nt_BP=1287nt
ATTGGTCCTTTTATGGTTCAGACTTCCTTCTTCATCGACTCTCCCTAATTCTCTTCACTGTTCATCCCCAGCAACTTTTCTTCCCAAGCA
TTTCCTGCGGGCTTTTATTACCCCAGGAGTGCCAATCAAGGCGTGGAACAGATAAAGCTGTGTAGCAACTAACGCGTGACTCTTGTGAGT
GTGGAGGGCAAACGAAGCTCCCTGAAACCTCCGCTCTGCTCTCCTGCCTTACGCCGCGCGGCCCCTGTTCTGAGGTTTAATACTTGCTTC
ACAGATAAGCGCTGCGGCCACGTTCCGGTGCCCACCTTCTCCTTGGCTAGGGCACGACGCCAGCCCAGGGGGCGCGGCCCTGAGCTGCTG
CGAGAGACAGCTGAAAGCGCCGGCCCGACGGCCTTGGCTCCCTCGGTGCGCTGGGCGCAGAGCACTCGGACCCTGGGCGCCCACTGCTCG
AGTACCTGCGCGGCTCCTAGCCAGGCTTAGCCCAGGCGCGGGCTGAGAGTCAGTTCGCCAGGTGGGCCTGGAGCCATGGGCTGGGTGGGC
GGGCGGCGCCGGGATTCTGCGTCACCACCTGGGCGGAGCCGTTCTGCTGCTGACGACATCAACCCGGCACCTGCCAACATGGAAGGTGGC
GGCGGCAGCGTCGCTGTAGCTGGCCTCGGAGCTCGAGGCTCTGGAGCGGCTGCAGCTACAGTCCGGGAACTTCTGCAGGACGGGTGTTAT
AGTGACTTTTTAAACGAAGACTTTGATGTAAAGACTTATACTTCTCAATCTATTCATCAAGCTGTAATTGCTGAACAACTAGCAAAACTT
GCCCAAGGAATCAGTCAGTTGGACAGAGAACTACACTTACAGGTTGTTGCAAGACATGAAGATTTACTGGCACAAGCAACTGGGATTGAG
TCGTTGGAAGGTGTTCTTCAGATGATGCAGACGAGAATTGGGGCTTTACAGGGAGCTGTTGATAGGATAAAAGCAAAAATTGTTGAACCA
TACAATAAGATAGTTGCCCGGACTGCACAACTAGCAAGACTTCAGGTTGCCTGTGATTTGCTTCGGAGGATTATTCGTATCTTGAATCTC
AGTAAGAGACTCCAAGGACAACTGCAAGGGGGAAGTAGAGAGATAACAAAAGCTGCTCAGAGTCTCAATGAACTTGATTATCTTTCTCAA
GGAATAGATCTTTCTGGAATAGAAGTGATAGAAAATGATCTACTTTTTATTGCAAGAGCCCGACTTGAAGTGGAAAATCAAGCTAAGCGC
CTACTAGAGCAGGGTTTGGAGACTCAGATATTTATTTTTGAAAACAATATCTACTACTGTGCACATGTCGGGAAACAGGCCATCCGTGTG
GTCTCCACTGGCAAGGAAGGTGTGATTTACAATGGCCTCAGTGACTGGCTGTATGAAGAGGAGATTTTGAAGACACACATCGCACACTGG
TGGTCTCCGGATGGCACGAGACTCGCCTACGCCGCCATCAATGATTCCCGTGTCCCCATCATGGAGCTCCCAACTTACACCGGCTCCATC
TACCCCACCGTGAAGCCCTACCACTATCCCAAGGCTGGAAGTGAGAACCCCAGCATTTCCCTACACGTTATTGGCTTAAATGGACCCACC
CATGATCTGGAGATGATGCCGCCTGATGATCCACGGATGAGGGAGTACTACATCACCATGGTGAAGTGGGCCACCAGCACCAAGGTCGCC
GTGACCTGGCTGAACCGGGCGCAGAACGTGTCCATCCTCACCCTCTGCGACGCCACCACGGGGGTCTGCACGAAGAAACACGAGGATGAA
AGTGAGGCCTGGCTCCACAGACAGAATGAAGAACCTGTGTTCTCCAAGGATGGCCGAAAGTTTTTCTTCATCAGAGCCATCCCCCAGGGA
GGACGAGGGAAATTCTATCACATCACGGTGTCCTCGTCCCAGCCCAACAGCAGCAACGACAACATCCAGTCCATCACCTCCGGGGACTGG
GACGTGACCAAGATCCTAGCCTACGATGAGAAGGGGAATAAGATCTACTTCCTGAGCACGGAGGACCTGCCTCGGAGACGACAACTCTAC
AGTGCCAACACGGTGGGCAACTTCAACAGGCAGTGCCTCTCCTGTGACCTGGTTGAGAACTGCACCTACTTCAGCGCTTCCTTCAGCCAT
AGCATGGACTTCTTCCTGCTCAAGTGCGAAGGTCCTGGTGTTCCTATGGTGACGGTGCACAACACAACAGATAAGAAAAAAATGTTTGAC
CTAGAAACAAATGAACATGTCAAGAAGGCCATAAATGACCGACAGATGCCTAAAGTGGAATACAGGGACATTGAGATTGATGATTACAAC
CTGCCCATGCAGATACTGAAGCCAGCAACCTTCACCGACACCACCCACTACCCTCTGCTCCTGGTGGTGGATGGCACCCCAGGCAGCCAG
AGTGTGGCTGAGAAGTTCGAGGTGAGCTGGGAGACGGTGATGGTGAGCAGCCACGGCGCGGTGGTGGTAAAGTGTGACGGCCGTGGCAGC
GGCTTCCAAGGGACCAAGCTCCTGCACGAAGTGAGGCGGCGGCTGGGCTTGCTGGAGGAGAAGGACCAGATGGAGGCCGTGCGGACGATG
CTGAAGGAGCAGTACATTGACAGGACGCGCGTGGCCGTGTTTGGGAAGGATTACGGTGGCTACCTGAGCACCTACATCCTCCCAGCAAAG
GGAGAAAATCAAGGCCAGACATTCACCTGCGGCTCTGCTCTCTCTCCAATAACAGACTTCAAACTCTATGCCTCTGCGTTTTCCGAGAGG
TACTTGGGCCTCCATGGACTTGACAACAGAGCATACGAGATGACCAAGGTAGCCCATCGAGTCTCCGCGCTGGAAGAACAGCAGTTCCTG
ATCATTCATCCCACTGCCGATGAAAAAATTCATTTCCAGCACACAGCAGAACTCATTACACAACTAATTAGGGGAAAGGCTAATTACAGC
TTACAGATTTACCCGGACGAAAGCCATTACTTTACCAGCTCCAGCCTCAAACAGCATCTGTACCGGTCCATCATCAACTTCTTCGTGGAA
TGCTTCAGGATCCAGGACAAACTGCTGACAGTCACAGCGAAAGAGGACGAGGAGGAGGACTAAGCTCAGGTCGCTCTAAGCACAAACGTG
GCTCTTTCTACAACCAGATGCAACCGAGGGATTTCCCTGCCCTCCCTCTTCCCTCGGAGGGGCGGGGCGGGGCGGGGCCGGGTGTTCCAT
AGCATGTGTGTCTCGGATGCGGAAGGCAGTTTTGCTTGGGAAACAAGCTCCTTCCCCGGGGTCATCACTCACGGCCTCCATGGCACCAGG
GACAACGCTGTCCCCGCAGCAGCGCCTCCTCCCGGCGCCCGAGAGACCGGCACGCCACGGCCCCTCCCCCAAGGAACAGAGCAAAGGATG
GTGGCCGCAGGCCCCACGCGAGCCCACAGGACACCGGCCCCTAGATTCCAGCCACCAAGCGGAAGCATGAGACCCGCCCACACTAGCCTC
TGTGTTCCCGTTAGGGACATCACACCCTGTCTCACGTCGCAGTGCCATGGACGCAGCAGTTACAGCACCATTGTTTTAGCAGTGCGTGTT
CATATATGGGCTTGCTACTTCCTGTAATGAGGACGTTCAACATGGTGAGGGGCTACAAGAAAACGCTTTTCTGTACAGAGTCTTACTGTA
GCTACGCTAATGGTTAACCTGATAGAATTAACTCGTATTTTTCTATGGTTTTAACCTGATGCTCCACTGTCTCCGTCATGGGGTTGTTTT
GCTGTTTGGGGTTGGGCCTTGTTTCCCTTTCCTTTCTCCAGTCCACGTGTAGACTTTGCGCTTGATGAAGAAGCAGATCGGAAGTAACTG
CTCCCTCCTCAAGGTTGTCTTCAGACGTCTTGGGGACGTTCCTAAACACTGAGGGGGAAGACAGCCAATAGCACCCATTAAAAGAAATAC
CTAAATAAAACCTCTCTCCCACTCAGCTATGCTAGGGCTTGGCTGTAGGTGTGCACTGTCTATTTACATCCGTCCTTACAACCATCCTTG
TCCTCCTTGGTACCGTATCAAGCTCTTTCCCATGACATTTGGTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGAAAAAAGACAAAGC
GTCAACTCCACCCACAGGCCCGCTGTGTGTGCTCGGGCCACGGGAGTCCTGAGGGTTCTGTGGGCCTGCGCGCATCCCTCTCCCATCGTG
GGGGTGGCTCCGTGACCTTCCTGCCACGAGCAGGAGGTTGATGATGTGCTACGTTAGCCTTGTAAGATACACCCCCACCAAATGTGCAGC
CGGTGTTCCCAGTGTATATTTCATTCTCTTGTATATAAAGGAAGCAATGTGTGTCAGGCCTCTGTGCAGTCAACCCAGCCTCCTCCCGCC
AGTGCTAACCCCGTGTTGAGCCTGCATGCTGACACTGTGGCCGATCTGGACTCTAGAAGTGCTAGTTTGAAATATATCCATTACTGTCAT
TTCCTTTTGAGCTTGTGGACAAGCTGAATGTCAGGACTGACTTCGCCAGCTCCCAGCCCTGCGGGGGTGTCCTTGGCATCCCATCAGCAG
AGGAGATGCGTCCCTGTTGCATTTTGGCGTTTGGGGCTTTGGGTTTATCCACATGAGCTCTGAACGTCCGTTATAGTTAGGGTGATTGGA
AGGTCTCCATCACTGGGTGTTTTAAAGGTGATTCACCACCATTTGTGAAAGGACCAACGTGCTGATAAACAGGACCGATCCGAGTGCTAC
ATGACTGTGCGTTTGCTATTTCAATGGGCCTGAACGACTACAAAGCCAGCTAGGTCTGGAAGGGGAAGCCAGCTCTGGCCACGACATCTG

>18020_18020_1_COG5-DPP6_COG5_chr7_107052947_ENST00000297135_DPP6_chr7_154519477_ENST00000404039_length(amino acids)=876AA_BP=265
MRVSSPGGPGAMGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSGAAAATVRELLQDGCYSDFLNEDFDVKTYT
SQSIHQAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARL
QVACDLLRRIIRILNLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGLETQIFIFE
NNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGS
ENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVF
SKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLS
CDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDT
THYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF
GKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQH

--------------------------------------------------------------
>18020_18020_2_COG5-DPP6_COG5_chr7_107052947_ENST00000347053_DPP6_chr7_154519477_ENST00000404039_length(transcript)=4454nt_BP=813nt
GCTTAGCCCAGGCGCGGGCTGAGAGTCAGTTCGCCAGGTGGGCCTGGAGCCATGGGCTGGGTGGGCGGGCGGCGCCGGGATTCTGCGTCA
CCACCTGGGCGGAGCCGTTCTGCTGCTGACGACATCAACCCGGCACCTGCCAACATGGAAGGTGGCGGCGGCAGCGTCGCTGTAGCTGGC
CTCGGAGCTCGAGGCTCTGGAGCGGCTGCAGCTACAGTCCGGGAACTTCTGCAGGACGGGTGTTATAGTGACTTTTTAAACGAAGACTTT
GATGTAAAGACTTATACTTCTCAATCTATTCATCAAGCTGTAATTGCTGAACAACTAGCAAAACTTGCCCAAGGAATCAGTCAGTTGGAC
AGAGAACTACACTTACAGGTTGTTGCAAGACATGAAGATTTACTGGCACAAGCAACTGGGATTGAGTCGTTGGAAGGTGTTCTTCAGATG
ATGCAGACGAGAATTGGGGCTTTACAGGGAGCTGTTGATAGGATAAAAGCAAAAATTGTTGAACCATACAATAAGATAGTTGCCCGGACT
GCACAACTAGCAAGACTTCAGGTTGCCTGTGATTTGCTTCGGAGGATTATTCGTATCTTGAATCTCAGTAAGAGACTCCAAGGACAACTG
CAAGGGGGAAGTAGAGAGATAACAAAAGCTGCTCAGAGTCTCAATGAACTTGATTATCTTTCTCAAGGAATAGATCTTTCTGGAATAGAA
GTGATAGAAAATGATCTACTTTTTATTGCAAGAGCCCGACTTGAAGTGGAAAATCAAGCTAAGCGCCTACTAGAGCAGGGTTTGGAGACT
CAGATATTTATTTTTGAAAACAATATCTACTACTGTGCACATGTCGGGAAACAGGCCATCCGTGTGGTCTCCACTGGCAAGGAAGGTGTG
ATTTACAATGGCCTCAGTGACTGGCTGTATGAAGAGGAGATTTTGAAGACACACATCGCACACTGGTGGTCTCCGGATGGCACGAGACTC
GCCTACGCCGCCATCAATGATTCCCGTGTCCCCATCATGGAGCTCCCAACTTACACCGGCTCCATCTACCCCACCGTGAAGCCCTACCAC
TATCCCAAGGCTGGAAGTGAGAACCCCAGCATTTCCCTACACGTTATTGGCTTAAATGGACCCACCCATGATCTGGAGATGATGCCGCCT
GATGATCCACGGATGAGGGAGTACTACATCACCATGGTGAAGTGGGCCACCAGCACCAAGGTCGCCGTGACCTGGCTGAACCGGGCGCAG
AACGTGTCCATCCTCACCCTCTGCGACGCCACCACGGGGGTCTGCACGAAGAAACACGAGGATGAAAGTGAGGCCTGGCTCCACAGACAG
AATGAAGAACCTGTGTTCTCCAAGGATGGCCGAAAGTTTTTCTTCATCAGAGCCATCCCCCAGGGAGGACGAGGGAAATTCTATCACATC
ACGGTGTCCTCGTCCCAGCCCAACAGCAGCAACGACAACATCCAGTCCATCACCTCCGGGGACTGGGACGTGACCAAGATCCTAGCCTAC
GATGAGAAGGGGAATAAGATCTACTTCCTGAGCACGGAGGACCTGCCTCGGAGACGACAACTCTACAGTGCCAACACGGTGGGCAACTTC
AACAGGCAGTGCCTCTCCTGTGACCTGGTTGAGAACTGCACCTACTTCAGCGCTTCCTTCAGCCATAGCATGGACTTCTTCCTGCTCAAG
TGCGAAGGTCCTGGTGTTCCTATGGTGACGGTGCACAACACAACAGATAAGAAAAAAATGTTTGACCTAGAAACAAATGAACATGTCAAG
AAGGCCATAAATGACCGACAGATGCCTAAAGTGGAATACAGGGACATTGAGATTGATGATTACAACCTGCCCATGCAGATACTGAAGCCA
GCAACCTTCACCGACACCACCCACTACCCTCTGCTCCTGGTGGTGGATGGCACCCCAGGCAGCCAGAGTGTGGCTGAGAAGTTCGAGGTG
AGCTGGGAGACGGTGATGGTGAGCAGCCACGGCGCGGTGGTGGTAAAGTGTGACGGCCGTGGCAGCGGCTTCCAAGGGACCAAGCTCCTG
CACGAAGTGAGGCGGCGGCTGGGCTTGCTGGAGGAGAAGGACCAGATGGAGGCCGTGCGGACGATGCTGAAGGAGCAGTACATTGACAGG
ACGCGCGTGGCCGTGTTTGGGAAGGATTACGGTGGCTACCTGAGCACCTACATCCTCCCAGCAAAGGGAGAAAATCAAGGCCAGACATTC
ACCTGCGGCTCTGCTCTCTCTCCAATAACAGACTTCAAACTCTATGCCTCTGCGTTTTCCGAGAGGTACTTGGGCCTCCATGGACTTGAC
AACAGAGCATACGAGATGACCAAGGTAGCCCATCGAGTCTCCGCGCTGGAAGAACAGCAGTTCCTGATCATTCATCCCACTGCCGATGAA
AAAATTCATTTCCAGCACACAGCAGAACTCATTACACAACTAATTAGGGGAAAGGCTAATTACAGCTTACAGATTTACCCGGACGAAAGC
CATTACTTTACCAGCTCCAGCCTCAAACAGCATCTGTACCGGTCCATCATCAACTTCTTCGTGGAATGCTTCAGGATCCAGGACAAACTG
CTGACAGTCACAGCGAAAGAGGACGAGGAGGAGGACTAAGCTCAGGTCGCTCTAAGCACAAACGTGGCTCTTTCTACAACCAGATGCAAC
CGAGGGATTTCCCTGCCCTCCCTCTTCCCTCGGAGGGGCGGGGCGGGGCGGGGCCGGGTGTTCCATAGCATGTGTGTCTCGGATGCGGAA
GGCAGTTTTGCTTGGGAAACAAGCTCCTTCCCCGGGGTCATCACTCACGGCCTCCATGGCACCAGGGACAACGCTGTCCCCGCAGCAGCG
CCTCCTCCCGGCGCCCGAGAGACCGGCACGCCACGGCCCCTCCCCCAAGGAACAGAGCAAAGGATGGTGGCCGCAGGCCCCACGCGAGCC
CACAGGACACCGGCCCCTAGATTCCAGCCACCAAGCGGAAGCATGAGACCCGCCCACACTAGCCTCTGTGTTCCCGTTAGGGACATCACA
CCCTGTCTCACGTCGCAGTGCCATGGACGCAGCAGTTACAGCACCATTGTTTTAGCAGTGCGTGTTCATATATGGGCTTGCTACTTCCTG
TAATGAGGACGTTCAACATGGTGAGGGGCTACAAGAAAACGCTTTTCTGTACAGAGTCTTACTGTAGCTACGCTAATGGTTAACCTGATA
GAATTAACTCGTATTTTTCTATGGTTTTAACCTGATGCTCCACTGTCTCCGTCATGGGGTTGTTTTGCTGTTTGGGGTTGGGCCTTGTTT
CCCTTTCCTTTCTCCAGTCCACGTGTAGACTTTGCGCTTGATGAAGAAGCAGATCGGAAGTAACTGCTCCCTCCTCAAGGTTGTCTTCAG
ACGTCTTGGGGACGTTCCTAAACACTGAGGGGGAAGACAGCCAATAGCACCCATTAAAAGAAATACCTAAATAAAACCTCTCTCCCACTC
AGCTATGCTAGGGCTTGGCTGTAGGTGTGCACTGTCTATTTACATCCGTCCTTACAACCATCCTTGTCCTCCTTGGTACCGTATCAAGCT
CTTTCCCATGACATTTGGTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAACAGAAAAAAGACAAAGCGTCAACTCCACCCACAGGCCCGCT
GTGTGTGCTCGGGCCACGGGAGTCCTGAGGGTTCTGTGGGCCTGCGCGCATCCCTCTCCCATCGTGGGGGTGGCTCCGTGACCTTCCTGC
CACGAGCAGGAGGTTGATGATGTGCTACGTTAGCCTTGTAAGATACACCCCCACCAAATGTGCAGCCGGTGTTCCCAGTGTATATTTCAT
TCTCTTGTATATAAAGGAAGCAATGTGTGTCAGGCCTCTGTGCAGTCAACCCAGCCTCCTCCCGCCAGTGCTAACCCCGTGTTGAGCCTG
CATGCTGACACTGTGGCCGATCTGGACTCTAGAAGTGCTAGTTTGAAATATATCCATTACTGTCATTTCCTTTTGAGCTTGTGGACAAGC
TGAATGTCAGGACTGACTTCGCCAGCTCCCAGCCCTGCGGGGGTGTCCTTGGCATCCCATCAGCAGAGGAGATGCGTCCCTGTTGCATTT
TGGCGTTTGGGGCTTTGGGTTTATCCACATGAGCTCTGAACGTCCGTTATAGTTAGGGTGATTGGAAGGTCTCCATCACTGGGTGTTTTA
AAGGTGATTCACCACCATTTGTGAAAGGACCAACGTGCTGATAAACAGGACCGATCCGAGTGCTACATGACTGTGCGTTTGCTATTTCAA
TGGGCCTGAACGACTACAAAGCCAGCTAGGTCTGGAAGGGGAAGCCAGCTCTGGCCACGACATCTGGTCGGAGGGAAGTGGGGATGTGGC

>18020_18020_2_COG5-DPP6_COG5_chr7_107052947_ENST00000347053_DPP6_chr7_154519477_ENST00000404039_length(amino acids)=876AA_BP=265
MRVSSPGGPGAMGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSGAAAATVRELLQDGCYSDFLNEDFDVKTYT
SQSIHQAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARL
QVACDLLRRIIRILNLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGLETQIFIFE
NNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGS
ENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVF
SKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLS
CDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDT
THYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF
GKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQH

--------------------------------------------------------------
>18020_18020_3_COG5-DPP6_COG5_chr7_107052947_ENST00000393603_DPP6_chr7_154519477_ENST00000404039_length(transcript)=4675nt_BP=1034nt
GGTTTAATACTTGCTTCACAGATAAGCGCTGCGGCCACGTTCCGGTGCCCACCTTCTCCTTGGCTAGGGCACGACGCCAGCCCAGGGGGC
GCGGCCCTGAGCTGCTGCGAGAGACAGCTGAAAGCGCCGGCCCGACGGCCTTGGCTCCCTCGGTGCGCTGGGCGCAGAGCACTCGGACCC
TGGGCGCCCACTGCTCGAGTACCTGCGCGGCTCCTAGCCAGGCTTAGCCCAGGCGCGGGCTGAGAGTCAGTTCGCCAGGTGGGCCTGGAG
CCATGGGCTGGGTGGGCGGGCGGCGCCGGGATTCTGCGTCACCACCTGGGCGGAGCCGTTCTGCTGCTGACGACATCAACCCGGCACCTG
CCAACATGGAAGGTGGCGGCGGCAGCGTCGCTGTAGCTGGCCTCGGAGCTCGAGGCTCTGGAGCGGCTGCAGCTACAGTCCGGGAACTTC
TGCAGGACGGGTGTTATAGTGACTTTTTAAACGAAGACTTTGATGTAAAGACTTATACTTCTCAATCTATTCATCAAGCTGTAATTGCTG
AACAACTAGCAAAACTTGCCCAAGGAATCAGTCAGTTGGACAGAGAACTACACTTACAGGTTGTTGCAAGACATGAAGATTTACTGGCAC
AAGCAACTGGGATTGAGTCGTTGGAAGGTGTTCTTCAGATGATGCAGACGAGAATTGGGGCTTTACAGGGAGCTGTTGATAGGATAAAAG
CAAAAATTGTTGAACCATACAATAAGATAGTTGCCCGGACTGCACAACTAGCAAGACTTCAGGTTGCCTGTGATTTGCTTCGGAGGATTA
TTCGTATCTTGAATCTCAGTAAGAGACTCCAAGGACAACTGCAAGGGGGAAGTAGAGAGATAACAAAAGCTGCTCAGAGTCTCAATGAAC
TTGATTATCTTTCTCAAGGAATAGATCTTTCTGGAATAGAAGTGATAGAAAATGATCTACTTTTTATTGCAAGAGCCCGACTTGAAGTGG
AAAATCAAGCTAAGCGCCTACTAGAGCAGGGTTTGGAGACTCAGATATTTATTTTTGAAAACAATATCTACTACTGTGCACATGTCGGGA
AACAGGCCATCCGTGTGGTCTCCACTGGCAAGGAAGGTGTGATTTACAATGGCCTCAGTGACTGGCTGTATGAAGAGGAGATTTTGAAGA
CACACATCGCACACTGGTGGTCTCCGGATGGCACGAGACTCGCCTACGCCGCCATCAATGATTCCCGTGTCCCCATCATGGAGCTCCCAA
CTTACACCGGCTCCATCTACCCCACCGTGAAGCCCTACCACTATCCCAAGGCTGGAAGTGAGAACCCCAGCATTTCCCTACACGTTATTG
GCTTAAATGGACCCACCCATGATCTGGAGATGATGCCGCCTGATGATCCACGGATGAGGGAGTACTACATCACCATGGTGAAGTGGGCCA
CCAGCACCAAGGTCGCCGTGACCTGGCTGAACCGGGCGCAGAACGTGTCCATCCTCACCCTCTGCGACGCCACCACGGGGGTCTGCACGA
AGAAACACGAGGATGAAAGTGAGGCCTGGCTCCACAGACAGAATGAAGAACCTGTGTTCTCCAAGGATGGCCGAAAGTTTTTCTTCATCA
GAGCCATCCCCCAGGGAGGACGAGGGAAATTCTATCACATCACGGTGTCCTCGTCCCAGCCCAACAGCAGCAACGACAACATCCAGTCCA
TCACCTCCGGGGACTGGGACGTGACCAAGATCCTAGCCTACGATGAGAAGGGGAATAAGATCTACTTCCTGAGCACGGAGGACCTGCCTC
GGAGACGACAACTCTACAGTGCCAACACGGTGGGCAACTTCAACAGGCAGTGCCTCTCCTGTGACCTGGTTGAGAACTGCACCTACTTCA
GCGCTTCCTTCAGCCATAGCATGGACTTCTTCCTGCTCAAGTGCGAAGGTCCTGGTGTTCCTATGGTGACGGTGCACAACACAACAGATA
AGAAAAAAATGTTTGACCTAGAAACAAATGAACATGTCAAGAAGGCCATAAATGACCGACAGATGCCTAAAGTGGAATACAGGGACATTG
AGATTGATGATTACAACCTGCCCATGCAGATACTGAAGCCAGCAACCTTCACCGACACCACCCACTACCCTCTGCTCCTGGTGGTGGATG
GCACCCCAGGCAGCCAGAGTGTGGCTGAGAAGTTCGAGGTGAGCTGGGAGACGGTGATGGTGAGCAGCCACGGCGCGGTGGTGGTAAAGT
GTGACGGCCGTGGCAGCGGCTTCCAAGGGACCAAGCTCCTGCACGAAGTGAGGCGGCGGCTGGGCTTGCTGGAGGAGAAGGACCAGATGG
AGGCCGTGCGGACGATGCTGAAGGAGCAGTACATTGACAGGACGCGCGTGGCCGTGTTTGGGAAGGATTACGGTGGCTACCTGAGCACCT
ACATCCTCCCAGCAAAGGGAGAAAATCAAGGCCAGACATTCACCTGCGGCTCTGCTCTCTCTCCAATAACAGACTTCAAACTCTATGCCT
CTGCGTTTTCCGAGAGGTACTTGGGCCTCCATGGACTTGACAACAGAGCATACGAGATGACCAAGGTAGCCCATCGAGTCTCCGCGCTGG
AAGAACAGCAGTTCCTGATCATTCATCCCACTGCCGATGAAAAAATTCATTTCCAGCACACAGCAGAACTCATTACACAACTAATTAGGG
GAAAGGCTAATTACAGCTTACAGATTTACCCGGACGAAAGCCATTACTTTACCAGCTCCAGCCTCAAACAGCATCTGTACCGGTCCATCA
TCAACTTCTTCGTGGAATGCTTCAGGATCCAGGACAAACTGCTGACAGTCACAGCGAAAGAGGACGAGGAGGAGGACTAAGCTCAGGTCG
CTCTAAGCACAAACGTGGCTCTTTCTACAACCAGATGCAACCGAGGGATTTCCCTGCCCTCCCTCTTCCCTCGGAGGGGCGGGGCGGGGC
GGGGCCGGGTGTTCCATAGCATGTGTGTCTCGGATGCGGAAGGCAGTTTTGCTTGGGAAACAAGCTCCTTCCCCGGGGTCATCACTCACG
GCCTCCATGGCACCAGGGACAACGCTGTCCCCGCAGCAGCGCCTCCTCCCGGCGCCCGAGAGACCGGCACGCCACGGCCCCTCCCCCAAG
GAACAGAGCAAAGGATGGTGGCCGCAGGCCCCACGCGAGCCCACAGGACACCGGCCCCTAGATTCCAGCCACCAAGCGGAAGCATGAGAC
CCGCCCACACTAGCCTCTGTGTTCCCGTTAGGGACATCACACCCTGTCTCACGTCGCAGTGCCATGGACGCAGCAGTTACAGCACCATTG
TTTTAGCAGTGCGTGTTCATATATGGGCTTGCTACTTCCTGTAATGAGGACGTTCAACATGGTGAGGGGCTACAAGAAAACGCTTTTCTG
TACAGAGTCTTACTGTAGCTACGCTAATGGTTAACCTGATAGAATTAACTCGTATTTTTCTATGGTTTTAACCTGATGCTCCACTGTCTC
CGTCATGGGGTTGTTTTGCTGTTTGGGGTTGGGCCTTGTTTCCCTTTCCTTTCTCCAGTCCACGTGTAGACTTTGCGCTTGATGAAGAAG
CAGATCGGAAGTAACTGCTCCCTCCTCAAGGTTGTCTTCAGACGTCTTGGGGACGTTCCTAAACACTGAGGGGGAAGACAGCCAATAGCA
CCCATTAAAAGAAATACCTAAATAAAACCTCTCTCCCACTCAGCTATGCTAGGGCTTGGCTGTAGGTGTGCACTGTCTATTTACATCCGT
CCTTACAACCATCCTTGTCCTCCTTGGTACCGTATCAAGCTCTTTCCCATGACATTTGGTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAA
CAGAAAAAAGACAAAGCGTCAACTCCACCCACAGGCCCGCTGTGTGTGCTCGGGCCACGGGAGTCCTGAGGGTTCTGTGGGCCTGCGCGC
ATCCCTCTCCCATCGTGGGGGTGGCTCCGTGACCTTCCTGCCACGAGCAGGAGGTTGATGATGTGCTACGTTAGCCTTGTAAGATACACC
CCCACCAAATGTGCAGCCGGTGTTCCCAGTGTATATTTCATTCTCTTGTATATAAAGGAAGCAATGTGTGTCAGGCCTCTGTGCAGTCAA
CCCAGCCTCCTCCCGCCAGTGCTAACCCCGTGTTGAGCCTGCATGCTGACACTGTGGCCGATCTGGACTCTAGAAGTGCTAGTTTGAAAT
ATATCCATTACTGTCATTTCCTTTTGAGCTTGTGGACAAGCTGAATGTCAGGACTGACTTCGCCAGCTCCCAGCCCTGCGGGGGTGTCCT
TGGCATCCCATCAGCAGAGGAGATGCGTCCCTGTTGCATTTTGGCGTTTGGGGCTTTGGGTTTATCCACATGAGCTCTGAACGTCCGTTA
TAGTTAGGGTGATTGGAAGGTCTCCATCACTGGGTGTTTTAAAGGTGATTCACCACCATTTGTGAAAGGACCAACGTGCTGATAAACAGG
ACCGATCCGAGTGCTACATGACTGTGCGTTTGCTATTTCAATGGGCCTGAACGACTACAAAGCCAGCTAGGTCTGGAAGGGGAAGCCAGC

>18020_18020_3_COG5-DPP6_COG5_chr7_107052947_ENST00000393603_DPP6_chr7_154519477_ENST00000404039_length(amino acids)=876AA_BP=265
MRVSSPGGPGAMGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSGAAAATVRELLQDGCYSDFLNEDFDVKTYT
SQSIHQAVIAEQLAKLAQGISQLDRELHLQVVARHEDLLAQATGIESLEGVLQMMQTRIGALQGAVDRIKAKIVEPYNKIVARTAQLARL
QVACDLLRRIIRILNLSKRLQGQLQGGSREITKAAQSLNELDYLSQGIDLSGIEVIENDLLFIARARLEVENQAKRLLEQGLETQIFIFE
NNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGS
ENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVF
SKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLS
CDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDT
THYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVF
GKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for COG5-DPP6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for COG5-DPP6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for COG5-DPP6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource