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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ACTN4-TIMM50 (FusionGDB2 ID:1804)

Fusion Gene Summary for ACTN4-TIMM50

Fusion gene summary

Fusion gene information	Fusion gene name: ACTN4-TIMM50
	Fusion gene ID: 1804
		Hgene	Tgene
	Gene symbol	ACTN4	TIMM50
	Gene ID	81	92609
	Gene name	actinin alpha 4	translocase of inner mitochondrial membrane 50
	Synonyms	ACTININ-4\|FSGS\|FSGS1	MGCA9\|TIM50\|TIM50L
	Cytomap	19q13.2	19q13.2
	Type of gene	protein-coding	protein-coding
	Description	alpha-actinin-4focal segmental glomerulosclerosis 1non-muscle alpha-actinin 4	mitochondrial import inner membrane translocase subunit TIM50Tim50-like proteinhomolog of yeast Tim50
	Modification date	20200327	20200327
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000252699, ENST00000390009, ENST00000424234, ENST00000497637,	ENST00000544017, ENST00000599794, ENST00000600878, ENST00000314349, ENST00000607714,
Fusion gene scores	* DoF score	42 X 60 X 18=45360	1 X 4 X 1=4
	# samples	77	1
	** MAII score	log2(77/45360*10)=-5.88041838424733 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(1/4*10)=1.32192809488736
Context	PubMed: ACTN4 [Title/Abstract] AND TIMM50 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ACTN4(39138547)-TIMM50(39976327), # samples:2 ACTN4(39138547)-TIMM50(39978700), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ACTN4	GO:0033209	tumor necrosis factor-mediated signaling pathway	25411248
Hgene	ACTN4	GO:0035357	peroxisome proliferator activated receptor signaling pathway	22351778
Hgene	ACTN4	GO:0048384	retinoic acid receptor signaling pathway	22351778
Hgene	ACTN4	GO:0051272	positive regulation of cellular component movement	9508771
Tgene	TIMM50	GO:0001836	release of cytochrome c from mitochondria	15044455
Tgene	TIMM50	GO:0006470	protein dephosphorylation	15044455

Fusion gene breakpoints across ACTN4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TIMM50 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	PRAD	TCGA-ZG-A9L1	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
ChimerDB4	PRAD	TCGA-ZG-A9L1	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
ChimerDB4	PRAD	TCGA-ZG-A9L1	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
ChimerDB4	PRAD	TCGA-ZG-A9L1	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+

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Fusion Gene ORF analysis for ACTN4-TIMM50

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000252699	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000252699	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000252699	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
5CDS-intron	ENST00000252699	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
5CDS-intron	ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000390009	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000390009	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000390009	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
5CDS-intron	ENST00000390009	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
5CDS-intron	ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000424234	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
5CDS-intron	ENST00000424234	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
5CDS-intron	ENST00000424234	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
5CDS-intron	ENST00000424234	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
In-frame	ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
In-frame	ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
In-frame	ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
In-frame	ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
intron-3CDS	ENST00000497637	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
intron-3CDS	ENST00000497637	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
intron-3CDS	ENST00000497637	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
intron-3CDS	ENST00000497637	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
intron-3CDS	ENST00000497637	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
intron-3CDS	ENST00000497637	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
intron-3CDS	ENST00000497637	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
intron-3CDS	ENST00000497637	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
intron-3CDS	ENST00000497637	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
intron-3CDS	ENST00000497637	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
intron-3CDS	ENST00000497637	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
intron-3CDS	ENST00000497637	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+
intron-intron	ENST00000497637	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
intron-intron	ENST00000497637	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
intron-intron	ENST00000497637	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
intron-intron	ENST00000497637	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
intron-intron	ENST00000497637	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+
intron-intron	ENST00000497637	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+
intron-intron	ENST00000497637	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+
intron-intron	ENST00000497637	ENST00000600878	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976327	+	1036	238	76	927	283
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976327	+	1182	238	76	927	283
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976327	+	1019	221	59	910	283
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976327	+	1165	221	59	910	283
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976327	+	968	170	8	859	283
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976327	+	1114	170	8	859	283
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978700	+	712	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978700	+	858	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978700	+	903	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978700	+	705	238	76	603	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978700	+	695	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978700	+	841	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978700	+	886	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978700	+	688	221	59	586	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978700	+	644	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978700	+	790	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978700	+	835	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978700	+	637	170	8	535	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978701	+	712	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978701	+	858	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978701	+	903	238	76	603	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978701	+	705	238	76	603	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978701	+	695	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978701	+	841	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978701	+	886	221	59	586	175
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978701	+	688	221	59	586	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39978701	+	644	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39978701	+	790	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000599794	TIMM50	chr19	39978701	+	835	170	8	535	175
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000544017	TIMM50	chr19	39978701	+	637	170	8	535	175
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976328	+	1036	238	76	927	283
ENST00000252699	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976328	+	1182	238	76	927	283
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976328	+	1019	221	59	910	283
ENST00000424234	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976328	+	1165	221	59	910	283
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000314349	TIMM50	chr19	39976328	+	968	170	8	859	283
ENST00000390009	ACTN4	chr19	39138547	+	ENST00000607714	TIMM50	chr19	39976328	+	1114	170	8	859	283

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.013782903	0.98621714
ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.01336413	0.98663586
ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.014026379	0.9859736
ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.013430076	0.98656994
ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.011038827	0.98896116
ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	0.011378299	0.98862165
ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006357857	0.99364215
ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006423901	0.9935761
ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.007850413	0.9921496
ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006004199	0.9939958
ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006899681	0.9931003
ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006793747	0.99320626
ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.007775204	0.9922248
ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.006690474	0.9933095
ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.004041911	0.99595803
ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.005097153	0.99490285
ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.007010265	0.99298966
ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	0.003764023	0.996236
ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006357857	0.99364215
ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006423901	0.9935761
ENST00000252699	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.007850413	0.9921496
ENST00000252699	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006004199	0.9939958
ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006899681	0.9931003
ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006793747	0.99320626
ENST00000424234	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.007775204	0.9922248
ENST00000424234	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.006690474	0.9933095
ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.004041911	0.99595803
ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.005097153	0.99490285
ENST00000390009	ENST00000599794	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.007010265	0.99298966
ENST00000390009	ENST00000544017	ACTN4	chr19	39138547	+	TIMM50	chr19	39978701	+	0.003764023	0.996236
ENST00000252699	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.013782903	0.98621714
ENST00000252699	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.01336413	0.98663586
ENST00000424234	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.014026379	0.9859736
ENST00000424234	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.013430076	0.98656994
ENST00000390009	ENST00000314349	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.011038827	0.98896116
ENST00000390009	ENST00000607714	ACTN4	chr19	39138547	+	TIMM50	chr19	39976328	+	0.011378299	0.98862165

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Fusion Genomic Features for ACTN4-TIMM50

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	6.23E-12	1
ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	1.38E-13	1
ACTN4	chr19	39138547	+	TIMM50	chr19	39976327	+	6.23E-12	1
ACTN4	chr19	39138547	+	TIMM50	chr19	39978700	+	1.38E-13	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ACTN4-TIMM50

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39138547/chr19:39976327)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

19_26

912.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

19_26

693.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

19_26

912.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

19_26

693.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

19_26

912.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

19_26

693.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

19_26

912.0

Compositional bias

Poly-Gly

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

19_26

693.0

Compositional bias

Poly-Gly

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000544017

143_286

241.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000607714

143_286

124

354.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000544017

143_286

241.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000607714

143_286

124

354.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000544017

143_286

119

241.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000544017

143_286

119

241.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000544017

45_65

241.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000544017

87_353

241.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000544017

45_65

241.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000544017

87_353

241.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000544017

66_86

241.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000544017

66_86

241.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

778_789

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

819_830

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

778_789

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

819_830

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

778_789

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

819_830

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

778_789

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

819_830

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

778_789

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

819_830

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

778_789

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

819_830

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

778_789

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

819_830

912.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

778_789

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

819_830

693.0

Calcium binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

163_269

912.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

50_154

912.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

765_800

912.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

806_841

912.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

163_269

693.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

50_154

693.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

765_800

693.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

806_841

693.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

163_269

912.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

50_154

912.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

765_800

912.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

806_841

912.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

163_269

693.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

50_154

693.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

765_800

693.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

806_841

693.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

163_269

912.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

50_154

912.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

765_800

912.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

806_841

912.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

163_269

693.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

50_154

693.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

765_800

693.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

806_841

693.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

163_269

912.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

50_154

912.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

765_800

912.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

806_841

912.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

163_269

693.0

Domain

Calponin-homology (CH) 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

50_154

693.0

Domain

Calponin-homology (CH) 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

765_800

693.0

Domain

EF-hand 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

806_841

693.0

Domain

EF-hand 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

84_88

912.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

84_88

693.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

84_88

912.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

84_88

693.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

84_88

912.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

84_88

693.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

84_88

912.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

84_88

693.0

Motif

LXXLL motif

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

177_192

912.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

1_269

912.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

177_192

693.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

1_269

693.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

177_192

912.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

1_269

912.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

177_192

693.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

1_269

693.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

177_192

912.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

1_269

912.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

177_192

693.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

1_269

693.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

177_192

912.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

1_269

912.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

177_192

693.0

Region

Polyphosphoinositide (PIP2)-binding

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

1_269

693.0

Region

Note=Actin-binding

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

293_403

912.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

413_518

912.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

528_639

912.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000252699

649_752

912.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

293_403

693.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

413_518

693.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

528_639

693.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39976327

ENST00000390009

649_752

693.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

293_403

912.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

413_518

912.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

528_639

912.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000252699

649_752

912.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

293_403

693.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

413_518

693.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

528_639

693.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39976328

ENST00000390009

649_752

693.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

293_403

912.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

413_518

912.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

528_639

912.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000252699

649_752

912.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

293_403

693.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

413_518

693.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

528_639

693.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39978700

ENST00000390009

649_752

693.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

293_403

912.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

413_518

912.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

528_639

912.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000252699

649_752

912.0

Repeat

Spectrin 4

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

293_403

693.0

Repeat

Spectrin 1

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

413_518

693.0

Repeat

Spectrin 2

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

528_639

693.0

Repeat

Spectrin 3

Hgene

ACTN4

chr19:39138547

chr19:39978701

ENST00000390009

649_752

693.0

Repeat

Spectrin 4

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000314349

143_286

227

457.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000314349

143_286

227

457.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000314349

143_286

335

457.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000607714

143_286

232

354.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000314349

143_286

335

457.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000607714

143_286

232

354.0

Domain

FCP1 homology

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000314349

45_65

227

457.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000314349

87_353

227

457.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000607714

45_65

124

354.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000607714

87_353

124

354.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000314349

45_65

227

457.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000314349

87_353

227

457.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000607714

45_65

124

354.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000607714

87_353

124

354.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000314349

45_65

335

457.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000314349

87_353

335

457.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000544017

45_65

119

241.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000544017

87_353

119

241.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000607714

45_65

232

354.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000607714

87_353

232

354.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000314349

45_65

335

457.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000314349

87_353

335

457.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000544017

45_65

119

241.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000544017

87_353

119

241.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000607714

45_65

232

354.0

Topological domain

Mitochondrial matrix

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000607714

87_353

232

354.0

Topological domain

Mitochondrial intermembrane

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000314349

66_86

227

457.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39976327

ENST00000607714

66_86

124

354.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000314349

66_86

227

457.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39976328

ENST00000607714

66_86

124

354.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000314349

66_86

335

457.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000544017

66_86

119

241.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978700

ENST00000607714

66_86

232

354.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000314349

66_86

335

457.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000544017

66_86

119

241.0

Transmembrane

Helical

Tgene

TIMM50

chr19:39138547

chr19:39978701

ENST00000607714

66_86

232

354.0

Transmembrane

Helical

Top

Fusion Gene Sequence for ACTN4-TIMM50

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>1804_1804_1_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976327_ENST00000314349_length(transcript)=1036nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCT
CCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCT
GGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTC
AGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATA
CATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCG
CCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGAC
CATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCA
AAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCG
CTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACT

>1804_1804_1_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976327_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_2_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976327_ENST00000607714_length(transcript)=1182nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCT
CCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCT
GGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTC
AGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATA
CATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCG
CCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGAC
CATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCA
AAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCG
CTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACT
TGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCC
GGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTG

>1804_1804_2_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976327_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_3_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976328_ENST00000314349_length(transcript)=1036nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCT
CCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCT
GGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTC
AGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATA
CATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCG
CCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGAC
CATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCA
AAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCG
CTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACT

>1804_1804_3_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976328_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_4_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976328_ENST00000607714_length(transcript)=1182nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCT
CCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCT
GGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTC
AGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATA
CATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCG
CCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGAC
CATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCA
AAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCG
CTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACT
TGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCC
GGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTG

>1804_1804_4_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39976328_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_5_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000314349_length(transcript)=712nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC

>1804_1804_5_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_6_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000544017_length(transcript)=705nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC

>1804_1804_6_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_7_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000599794_length(transcript)=903nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC
CTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCC
CGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGG
GGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTGGTCTCGGAATCTAAAAACCCTCGCTGTGTCTTCCTGTGTGTTGCGTGATCTGTG

>1804_1804_7_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_8_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000607714_length(transcript)=858nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC
CTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCC
CGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGG

>1804_1804_8_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978700_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_9_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000314349_length(transcript)=712nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC

>1804_1804_9_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_10_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000544017_length(transcript)=705nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC

>1804_1804_10_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_11_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000599794_length(transcript)=903nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC
CTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCC
CGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGG
GGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTGGTCTCGGAATCTAAAAACCCTCGCTGTGTCTTCCTGTGTGTTGCGTGATCTGTG

>1804_1804_11_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_12_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000607714_length(transcript)=858nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCG
AGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGA
CCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCT
GGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAA
CAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGC
CTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCC
CGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGG

>1804_1804_12_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000252699_TIMM50_chr19_39978701_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_13_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976327_ENST00000314349_length(transcript)=968nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCG
AGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCC
TCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTAT
ATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCC
TATTCCGGGACGCCACAAGATACATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGG
ACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGG
ATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGC
TGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCT
TCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCC

>1804_1804_13_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976327_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_14_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976327_ENST00000607714_length(transcript)=1114nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCG
AGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCC
TCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTAT
ATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCC
TATTCCGGGACGCCACAAGATACATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGG
ACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGG
ATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGC
TGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCT
TCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCC
CCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGA
TGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGA

>1804_1804_14_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976327_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_15_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976328_ENST00000314349_length(transcript)=968nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCG
AGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCC
TCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTAT
ATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCC
TATTCCGGGACGCCACAAGATACATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGG
ACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGG
ATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGC
TGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCT
TCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCC

>1804_1804_15_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976328_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_16_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976328_ENST00000607714_length(transcript)=1114nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCG
AGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGGAACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCC
TCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGTTTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTAT
ATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTGCGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCC
TATTCCGGGACGCCACAAGATACATGGATGGACACCATGTAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGG
ACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGG
ATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGC
TGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCT
TCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCC
CCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGA
TGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGA

>1804_1804_16_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39976328_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_17_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000314349_length(transcript)=644nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC

>1804_1804_17_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_18_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000544017_length(transcript)=637nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC

>1804_1804_18_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_19_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000599794_length(transcript)=835nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC
AGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTG
ATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTGGTCTCGGAATCTAAAAACCCTCGCTGTGTCTT

>1804_1804_19_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_20_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000607714_length(transcript)=790nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC
AGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTG

>1804_1804_20_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978700_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_21_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000314349_length(transcript)=644nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC

>1804_1804_21_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_22_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000544017_length(transcript)=637nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC

>1804_1804_22_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_23_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000599794_length(transcript)=835nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC
AGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTG
ATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCAGAGCAGATTTTTCACCCTGGTCTCGGAATCTAAAAACCCTCGCTGTGTCTT

>1804_1804_23_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_24_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000607714_length(transcript)=790nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCAT
GTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGC
CCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAA
CCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCC
TGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTC
TGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCC
AGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTG

>1804_1804_24_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000390009_TIMM50_chr19_39978701_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_25_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976327_ENST00000314349_length(transcript)=1019nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGG
AACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGT
TTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTG
CGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATACATGGATGGACACCATG
TAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACG
GCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTG
TGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGG
AGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCA
AACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCC

>1804_1804_25_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976327_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_26_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976327_ENST00000607714_length(transcript)=1165nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGG
AACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGT
TTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTG
CGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATACATGGATGGACACCATG
TAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACG
GCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTG
TGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGG
AGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCA
AACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCC
AATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATC

>1804_1804_26_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976327_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_27_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976328_ENST00000314349_length(transcript)=1019nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGG
AACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGT
TTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTG
CGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATACATGGATGGACACCATG
TAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACG
GCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTG
TGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGG
AGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCA
AACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCC

>1804_1804_27_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976328_ENST00000314349_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_28_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976328_ENST00000607714_length(transcript)=1165nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGATGATCATCGAGCCCACCAGCCCTTGCCTTCTCCCAGACCCTCTGCAGG
AACCGTACTACCAGCCACCCTACACGCTCGTTTTGGAGCTCACCGGCGTCCTCTTGCATCCTGAGTGGTCGCTGGCCACTGGCTGGAGGT
TTAAGAAGCGCCCAGGCATCGAGACCTTGTTCCAGCAGCTTGCCCCTTTATATGAAATTGTCATCTTTACGTCAGAGACTGGCATGACTG
CGTTTCCACTCATTGATAGTGTGGACCCCCATGGCTTCATCTCCTACCGCCTATTCCGGGACGCCACAAGATACATGGATGGACACCATG
TAAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACTGCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACG
GCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATCTGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTG
TGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGGCGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGG
AGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCCTTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCA
AACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCC
AATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATC

>1804_1804_28_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39976328_ENST00000607714_length(amino acids)=283AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLH
PEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDSVDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCK
KEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLAELSKSNKQNLFLG

--------------------------------------------------------------
>1804_1804_29_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000314349_length(transcript)=695nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA

>1804_1804_29_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_30_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000544017_length(transcript)=688nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA

>1804_1804_30_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_31_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000599794_length(transcript)=886nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA
GTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGG
GGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCA

>1804_1804_31_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_32_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000607714_length(transcript)=841nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA
GTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGG
GGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCA

>1804_1804_32_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978700_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_33_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000314349_length(transcript)=695nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA

>1804_1804_33_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000314349_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_34_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000544017_length(transcript)=688nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA

>1804_1804_34_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000544017_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_35_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000599794_length(transcript)=886nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA
GTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGG
GGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCA

>1804_1804_35_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000599794_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------
>1804_1804_36_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000607714_length(transcript)=841nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGGATATTTCATGTCTGAATCGGGACCCAGCTCGAGTAGTAGTTGTGGACT
GCAAGAAGGAAGCCTTCCGCCTGCAGCCCTATAACGGCGTTGCCCTGCGGCCCTGGGACGGCAACTCTGATGACCGGGTCTTGTTGGATC
TGTCTGCCTTCCTCAAGACCATTGCACTGAATGGTGTGGAGGACGTGCGAACCGTGCTGGAGCACTATGCCCTGGAGGATGACCCGCTGG
CGGCTTTCAAACAGCGGCAAAGCCGGCTAGAGCAGGAGGAGCAGCAGCGCCTGGCCGAGCTCTCCAAGTCCAACAAGCAGAACCTCTTCC
TTGGCTCCCTCACCAGCCGCTTGTGGCCTCGCTCCAAACAGCCCTGAACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCA
GTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCAATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGG
GGGCATCAGGGTGAGGTCCGGGACTCTTGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCA

>1804_1804_36_ACTN4-TIMM50_ACTN4_chr19_39138547_ENST00000424234_TIMM50_chr19_39978701_ENST00000607714_length(amino acids)=175AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACTN4-TIMM50

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000252699	+	1	21	12_26	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000390009	+	1	14	12_26	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000252699	+	1	21	12_26	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000390009	+	1	14	12_26	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000252699	+	1	21	12_26	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000390009	+	1	14	12_26	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000252699	+	1	21	12_26	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000390009	+	1	14	12_26	54.0	693.0	VCL

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000252699	+	1	21	108_126	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000252699	+	1	21	40_61	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000390009	+	1	14	108_126	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976327	ENST00000390009	+	1	14	40_61	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000252699	+	1	21	108_126	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000252699	+	1	21	40_61	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000390009	+	1	14	108_126	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39976328	ENST00000390009	+	1	14	40_61	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000252699	+	1	21	108_126	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000252699	+	1	21	40_61	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000390009	+	1	14	108_126	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978700	ENST00000390009	+	1	14	40_61	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000252699	+	1	21	108_126	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000252699	+	1	21	40_61	54.0	912.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000390009	+	1	14	108_126	54.0	693.0	VCL
Hgene	ACTN4	chr19:39138547	chr19:39978701	ENST00000390009	+	1	14	40_61	54.0	693.0	VCL

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for ACTN4-TIMM50

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ACTN4-TIMM50

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source