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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:COL27A1-ZNF618 (FusionGDB2 ID:18271)

Fusion Gene Summary for COL27A1-ZNF618

check button Fusion gene summary
Fusion gene informationFusion gene name: COL27A1-ZNF618
Fusion gene ID: 18271
HgeneTgene
Gene symbol

COL27A1

ZNF618

Gene ID

85301

114991

Gene namecollagen type XXVII alpha 1 chainzinc finger protein 618
SynonymsSTLSFP13169|NEDD10
Cytomap

9q32

9q32

Type of geneprotein-codingprotein-coding
Descriptioncollagen alpha-1(XXVII) chaincollagen, type XXVII, alpha 1zinc finger protein 618neural precursor cell expressed, developmentally down-regulated 10
Modification date2020031320200313
UniProtAcc

Q8IZC6

.
Ensembl transtripts involved in fusion geneENST00000356083, ENST00000477421, 
ENST00000470105, ENST00000288466, 
ENST00000374126, 
Fusion gene scores* DoF score12 X 10 X 7=8404 X 5 X 3=60
# samples 126
** MAII scorelog2(12/840*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/60*10)=0
Context

PubMed: COL27A1 [Title/Abstract] AND ZNF618 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCOL27A1(116999995)-ZNF618(116750601), # samples:3
Anticipated loss of major functional domain due to fusion event.COL27A1-ZNF618 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
COL27A1-ZNF618 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
COL27A1-ZNF618 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across COL27A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF618 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OQ-01ACOL27A1chr9

117054490

+ZNF618chr9

116731397

+
ChimerDB4ESCATCGA-L5-A4OQCOL27A1chr9

117054490

+ZNF618chr9

116731396

+
ChimerDB4ESCATCGA-L5-A4OS-01ACOL27A1chr9

116999995

-ZNF618chr9

116750601

+
ChimerDB4ESCATCGA-L5-A4OS-01ACOL27A1chr9

116999995

+ZNF618chr9

116750601

+
ChimerDB4ESCATCGA-L5-A4OSCOL27A1chr9

116999995

+ZNF618chr9

116750600

+
ChimerDB4ESCATCGA-L5-A4OSCOL27A1chr9

116999995

+ZNF618chr9

116750601

+


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Fusion Gene ORF analysis for COL27A1-ZNF618

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000356083ENST00000470105COL27A1chr9

117054490

+ZNF618chr9

116731397

+
5CDS-intronENST00000356083ENST00000470105COL27A1chr9

117054490

+ZNF618chr9

116731396

+
5CDS-intronENST00000356083ENST00000470105COL27A1chr9

116999995

+ZNF618chr9

116750601

+
5CDS-intronENST00000356083ENST00000470105COL27A1chr9

116999995

+ZNF618chr9

116750600

+
Frame-shiftENST00000356083ENST00000288466COL27A1chr9

116999995

+ZNF618chr9

116750601

+
Frame-shiftENST00000356083ENST00000288466COL27A1chr9

116999995

+ZNF618chr9

116750600

+
Frame-shiftENST00000356083ENST00000374126COL27A1chr9

116999995

+ZNF618chr9

116750601

+
Frame-shiftENST00000356083ENST00000374126COL27A1chr9

116999995

+ZNF618chr9

116750600

+
In-frameENST00000356083ENST00000288466COL27A1chr9

117054490

+ZNF618chr9

116731397

+
In-frameENST00000356083ENST00000288466COL27A1chr9

117054490

+ZNF618chr9

116731396

+
In-frameENST00000356083ENST00000374126COL27A1chr9

117054490

+ZNF618chr9

116731397

+
In-frameENST00000356083ENST00000374126COL27A1chr9

117054490

+ZNF618chr9

116731396

+
intron-3CDSENST00000477421ENST00000288466COL27A1chr9

117054490

+ZNF618chr9

116731397

+
intron-3CDSENST00000477421ENST00000288466COL27A1chr9

117054490

+ZNF618chr9

116731396

+
intron-3CDSENST00000477421ENST00000288466COL27A1chr9

116999995

+ZNF618chr9

116750601

+
intron-3CDSENST00000477421ENST00000288466COL27A1chr9

116999995

+ZNF618chr9

116750600

+
intron-3CDSENST00000477421ENST00000374126COL27A1chr9

117054490

+ZNF618chr9

116731397

+
intron-3CDSENST00000477421ENST00000374126COL27A1chr9

117054490

+ZNF618chr9

116731396

+
intron-3CDSENST00000477421ENST00000374126COL27A1chr9

116999995

+ZNF618chr9

116750601

+
intron-3CDSENST00000477421ENST00000374126COL27A1chr9

116999995

+ZNF618chr9

116750600

+
intron-intronENST00000477421ENST00000470105COL27A1chr9

117054490

+ZNF618chr9

116731397

+
intron-intronENST00000477421ENST00000470105COL27A1chr9

117054490

+ZNF618chr9

116731396

+
intron-intronENST00000477421ENST00000470105COL27A1chr9

116999995

+ZNF618chr9

116750601

+
intron-intronENST00000477421ENST00000470105COL27A1chr9

116999995

+ZNF618chr9

116750600

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356083COL27A1chr9117054490+ENST00000374126ZNF618chr9116731397+7861497539178062471
ENST00000356083COL27A1chr9117054490+ENST00000288466ZNF618chr9116731397+13952497539175272378
ENST00000356083COL27A1chr9117054490+ENST00000374126ZNF618chr9116731396+7861497539178062471
ENST00000356083COL27A1chr9117054490+ENST00000288466ZNF618chr9116731396+13952497539175272378

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356083ENST00000374126COL27A1chr9117054490+ZNF618chr9116731397+0.0031280370.996872
ENST00000356083ENST00000288466COL27A1chr9117054490+ZNF618chr9116731397+0.0010148570.9989851
ENST00000356083ENST00000374126COL27A1chr9117054490+ZNF618chr9116731396+0.0031280370.996872
ENST00000356083ENST00000288466COL27A1chr9117054490+ZNF618chr9116731396+0.0010148570.9989851

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Fusion Genomic Features for COL27A1-ZNF618


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
COL27A1chr9117054490+ZNF618chr9116731396+0.918589830.08141022
COL27A1chr9117054490+ZNF618chr9116731396+0.918589830.08141022
COL27A1chr9116999995+ZNF618chr9116750600+0.0002406310.9997594
COL27A1chr9116999995+ZNF618chr9116750600+0.0002406310.9997594
COL27A1chr9117054490+ZNF618chr9116731396+0.918589830.08141022
COL27A1chr9117054490+ZNF618chr9116731396+0.918589830.08141022
COL27A1chr9116999995+ZNF618chr9116750600+0.0002406310.9997594
COL27A1chr9116999995+ZNF618chr9116750600+0.0002406310.9997594

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for COL27A1-ZNF618


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:116999995/chr9:116750601)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
COL27A1

Q8IZC6

.
FUNCTION: Plays a role during the calcification of cartilage and the transition of cartilage to bone. {ECO:0000269|PubMed:17693149}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611003_106215281861.0DomainNote=Collagen-like 7
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611066_112515281861.0DomainNote=Collagen-like 8
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611126_118515281861.0DomainNote=Collagen-like 9
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611192_125115281861.0DomainNote=Collagen-like 10
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611258_131715281861.0DomainNote=Collagen-like 11
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611318_137815281861.0DomainNote=Collagen-like 12
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611382_144115281861.0DomainNote=Collagen-like 13
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611442_150115281861.0DomainNote=Collagen-like 14
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961625_67915281861.0DomainNote=Collagen-like 1
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961688_74715281861.0DomainNote=Collagen-like 2
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+496171_23615281861.0DomainNote=Laminin G-like
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961748_80715281861.0DomainNote=Collagen-like 3
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961808_86715281861.0DomainNote=Collagen-like 4
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961871_93015281861.0DomainNote=Collagen-like 5
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961931_99015281861.0DomainNote=Collagen-like 6
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611003_106215281861.0DomainNote=Collagen-like 7
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611066_112515281861.0DomainNote=Collagen-like 8
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611126_118515281861.0DomainNote=Collagen-like 9
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611192_125115281861.0DomainNote=Collagen-like 10
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611258_131715281861.0DomainNote=Collagen-like 11
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611318_137815281861.0DomainNote=Collagen-like 12
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611382_144115281861.0DomainNote=Collagen-like 13
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611442_150115281861.0DomainNote=Collagen-like 14
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961625_67915281861.0DomainNote=Collagen-like 1
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961688_74715281861.0DomainNote=Collagen-like 2
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+496171_23615281861.0DomainNote=Laminin G-like
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961748_80715281861.0DomainNote=Collagen-like 3
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961808_86715281861.0DomainNote=Collagen-like 4
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961871_93015281861.0DomainNote=Collagen-like 5
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961931_99015281861.0DomainNote=Collagen-like 6
TgeneZNF618chr9:117054490chr9:116731396ENST00000288466014147_16911862.0Zinc fingerC2H2-type 1
TgeneZNF618chr9:117054490chr9:116731396ENST00000288466014188_21011862.0Zinc fingerC2H2-type 2
TgeneZNF618chr9:117054490chr9:116731396ENST00000288466014256_27811862.0Zinc fingerC2H2-type 3
TgeneZNF618chr9:117054490chr9:116731396ENST00000288466014392_41411862.0Zinc fingerC2H2-type 4
TgeneZNF618chr9:117054490chr9:116731396ENST00000374126015147_16911955.0Zinc fingerC2H2-type 1
TgeneZNF618chr9:117054490chr9:116731396ENST00000374126015188_21011955.0Zinc fingerC2H2-type 2
TgeneZNF618chr9:117054490chr9:116731396ENST00000374126015256_27811955.0Zinc fingerC2H2-type 3
TgeneZNF618chr9:117054490chr9:116731396ENST00000374126015392_41411955.0Zinc fingerC2H2-type 4
TgeneZNF618chr9:117054490chr9:116731397ENST00000288466014147_16911862.0Zinc fingerC2H2-type 1
TgeneZNF618chr9:117054490chr9:116731397ENST00000288466014188_21011862.0Zinc fingerC2H2-type 2
TgeneZNF618chr9:117054490chr9:116731397ENST00000288466014256_27811862.0Zinc fingerC2H2-type 3
TgeneZNF618chr9:117054490chr9:116731397ENST00000288466014392_41411862.0Zinc fingerC2H2-type 4
TgeneZNF618chr9:117054490chr9:116731397ENST00000374126015147_16911955.0Zinc fingerC2H2-type 1
TgeneZNF618chr9:117054490chr9:116731397ENST00000374126015188_21011955.0Zinc fingerC2H2-type 2
TgeneZNF618chr9:117054490chr9:116731397ENST00000374126015256_27811955.0Zinc fingerC2H2-type 3
TgeneZNF618chr9:117054490chr9:116731397ENST00000374126015392_41411955.0Zinc fingerC2H2-type 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961283_162115281861.0Compositional biasNote=Pro-rich
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961283_162115281861.0Compositional biasNote=Pro-rich
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611502_156115281861.0DomainNote=Collagen-like 15
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611562_162115281861.0DomainNote=Collagen-like 16
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+49611660_186015281861.0DomainFibrillar collagen NC1
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611502_156115281861.0DomainNote=Collagen-like 15
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611562_162115281861.0DomainNote=Collagen-like 16
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+49611660_186015281861.0DomainFibrillar collagen NC1
HgeneCOL27A1chr9:117054490chr9:116731396ENST00000356083+4961625_161815281861.0RegionNote=Triple-helical region
HgeneCOL27A1chr9:117054490chr9:116731397ENST00000356083+4961625_161815281861.0RegionNote=Triple-helical region


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Fusion Gene Sequence for COL27A1-ZNF618


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>18271_18271_1_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731396_ENST00000288466_length(transcript)=13952nt_BP=4975nt
CGGCGGGGAGGCAGCTTCCACCGCCCTCCGCGCGCCCTCACCCGGCCTTGCTCTGCCTCCGGGGACCGCCAGCAGCCCGCCTCCAAAAGT
TTGATCATCTCTCTCTCTCTTTTTCTTGCTTCTTCTTCCTTTTTGGTGGAAGCAGAAAAGGACCGAGGCAGGGGCGAGCGCGGCGCCCGG
ACTCCTGGGACCATGGGCCTGGCGCGGGCGCCCGCGGGGCCCCAGCCGCGCTGCCTGCCTGCTCGGGCGCCCCTGGGCGCGGGGCTGCGC
TGGGGGCGCGGGGGCCGCGCGCTCTAAGCCGGCCTGGCGCGGCGGGGCGGGGGGCTGGCGGCCCCATGGGGCGCGCCCACACTTGCCCCC
CGGGCTCGGGAGCATGAAGTAGGGGCCTGCCATGGGAGCGGGATCGGCGCGGGGGGCCCGAGGCACAGCGGCGGCGGCGGCGGCGCGCGG
GGGGGGGTTTCTCTTCTCCTGGATCTTAGTCTCGTTTGCCTGTCACCTGGCCTCCACCCAAGGAGCTCCTGAAGATGTGGACATCCTCCA
GCGGCTGGGCCTCAGCTGGACGAAGGCCGGGAGCCCTGCACCCCCGGGAGTCATTCCTTTCCAGTCGGGCTTCATCTTTACGCAGCGGGC
CCGGCTCCAGGCTCCCACGGGCACCGTCATTCCTGCCGCCTTGGGCACAGAGCTGGCACTGGTGCTGAGCCTCTGCTCCCACCGGGTGAA
CCATGCCTTCCTCTTCGCTGTCCGCAGCCAGAAACGCAAGCTGCAGCTGGGCCTGCAGTTCCTCCCCGGCAAGACGGTCGTCCACCTCGG
GTCCCGGCGCTCAGTGGCCTTCGACCTCGACATGCACGACGGGCGCTGGCACCACCTGGCCCTCGAGCTCCGAGGCCGCACAGTCACTCT
GGTGACTGCCTGCGGGCAGCGCCGGGTGCCTGTCCTGCTGCCTTTCCACAGGGACCCTGCACTCGACCCTGGGGGCTCCTTCCTCTTTGG
GAAGATGAACCCGCATGCAGTCCAGTTTGAAGGTGCTCTCTGCCAGTTCAGTATCTACCCTGTGACGCAGGTCGCTCACAATTACTGTAC
CCACCTGAGGAAGCAGTGTGGACAGGCTGACACGTACCAGTCCCCACTGGGACCTCTCTTCTCCCAAGACTCTGGCAGACCTTTTACCTT
CCAGTCCGACCTCGCCCTGCTAGGCCTGGAGAACTTGACCACTGCCACACCAGCCCTGGGGTCACTGCCAGCAGGCAGGGGACCCAGGGG
GACTGTGGCACCCGCCACGCCCACCAAGCCCCAAAGGACTAGCCCCACAAACCCTCACCAGCATATGGCGGTGGGAGGCCCAGCCCAAAC
CCCGCTGCTACCTGCCAAGCTGTCAGCCAGTAACGCACTTGATCCCATGCTCCCAGCCTCTGTTGGCGGCTCTACCAGAACGCCTCGCCC
TGCGGCCGCTCAACCATCACAGAAGATCACAGCCACCAAAATCCCCAAAAGCCTCCCTACCAAGCCTTCGGCCCCTTCTACTTCAATTGT
GCCCATCAAAAGCCCCCATCCTACCCAGAAAACAGCTCCATCTTCATTTACAAAGTCAGCCCTACCCACTCAGAAGCAAGTGCCACCTAC
TTCCCGTCCAGTTCCTGCCAGAGTCTCCCGTCCCGCAGAGAAGCCCATCCAGAGGAACCCGGGAATGCCCAGGCCCCCACCGCCCAGCAC
CCGGCCCCTACCTCCTACCACCAGCTCCTCTAAAAAACCCATTCCCACACTAGCTCGGACTGAGGCCAAGATAACCAGCCATGCCAGTAA
GCCGGCCTCTGCCCGCACCAGCACCCACAAACCTCCCCCATTTACTGCTTTATCCTCATCTCCTGCCCCTACTCCTGGTTCTACCAGGAG
TACTCGGCCACCAGCCACGATGGTACCTCCAACTTCGGGCACCAGCACTCCCAGAACAGCACCTGCCGTCCCCACTCCTGGCTCAGCTCC
CACTGGAAGCAAGAAGCCCATTGGATCGGAAGCCTCAAAGAAAGCCGGACCCAAGAGCAGCCCCCGGAAGCCTGTCCCCCTCAGACCTGG
GAAGGCAGCCAGGGATGTCCCCTTGAGCGATCTGACAACCAGGCCTAGCCCCAGACAGCCCCAGCCCAGTCAGCAGACCACCCCGGCCCT
GGTATTGGCCCCGGCGCAATTCCTGTCCTCCAGCCCCCGGCCCACGAGCAGTGGCTATTCGATCTTCCACCTGGCAGGATCTACGCCTTT
CCCTCTGCTGATGGGGCCTCCGGGACCCAAGGGAGACTGTGGCTTGCCGGGTCCCCCTGGGCTACCTGGGCTACCTGGAATCCCTGGTGC
ACGTGGGCCTCGGGGTCCTCCTGGGCCTTATGGAAATCCAGGTCTCCCCGGCCCTCCTGGAGCCAAAGGACAGAAAGGGGACCCAGGGCT
CTCACCAGGAAAGGCCCACGATGGGGCAAAGGGTGACATGGGCTTGCCTGGGCTCTCCGGGAATCCAGGACCTCCGGGACGAAAGGGACA
CAAGGGCTATCCTGGACCGGCAGGGCACCCCGGAGAACAGGGGCAGCCAGGACCTGAGGGCAGCCCAGGGGCCAAAGGTTACCCTGGCAG
GCAGGGGTTACCTGGACCGGTAGGAGATCCCGGCCCCAAAGGCAGCAGGGGCTACATTGGGCTCCCAGGGCTCTTCGGCCTGCCAGGGTC
TGATGGAGAACGAGGCCTGCCTGGCGTTCCTGGCAAGAGGGGCAAGATGGGTATGCCGGGGTTTCCTGGAGTCTTTGGGGAAAGAGGCCC
TCCTGGACTGGATGGAAATCCTGGAGAACTGGGCCTGCCAGGCCCCCCTGGAGTCCCCGGCCTCATTGGTGACTTAGGAGTGTTGGGTCC
GATTGGCTACCCGGGACCCAAGGGCATGAAGGGACTGATGGGCAGCGTGGGGGAGCCCGGACTGAAAGGTGATAAGGGTGAACAAGGGGT
TCCAGGTGTGTCAGGAGATCCCGGATTCCAAGGAGACAAGGGGAGCCAGGGGTTGCCAGGGTTCCCCGGTGCACGGGGGAAGCCAGGGCC
TCTGGGCAAAGTCGGAGACAAAGGATCCATTGGGTTTCCCGGGCCCCCTGGACCCGAGGGATTCCCAGGAGACATCGGCCCCCCTGGCGA
CAATGGCCCAGAAGGCATGAAGGGTAAGCCTGGAGCCCGAGGCCTGCCGGGACCCCGTGGGCAGCTGGGGCCCGAGGGAGATGAGGGACC
CATGGGGCCGCCAGGGGCCCCTGGCTTGGAGGGTCAGCCTGGCAGGAAGGGGTTTCCTGGGAGGCCCGGCCTGGATGGCGTGAAGGGGGA
ACCAGGGGATCCTGGTCGGCCGGGGCCTGTGGGAGAGCAGGGATTTATGGGATTCATTGGTCTGGTCGGGGAGCCAGGAATCGTGGGAGA
AAAGGGTGATCGTGGCATGATGGGACCCCCAGGCGTGCCTGGACCCAAGGGGTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGAC
CCCTGGAGAGCCTGGACCCCAGGGTCCTCCAGGATCTCGAGGCCCACCAGGCATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACC
GGACGGACCAGCTGGGGAGCAAGGGTCCAGGGGCCTGAAGGGCCCTCCAGGACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGT
GGCTGGTGAGCGAGGCCACTTGGGCTCGAGAGGCTTTCCTGGCATCCCGGGTCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGA
ACCGGGCCCTCAGGGACCCCAGGGGCCAATTGGGCCTCCAGGAGAGATGGGACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCT
TCCTGGGGAAGCCGGGATGAAGGGTGACCTTGGACCCCTGGGCACTCCTGGGGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCT
TGAGGGTGACAGTGGCCCCATGGGACCTGATGGGCTGAAGGGGGACAGGGGAGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCA
GGAAGGGCTGATGGGTGAGGACGGGCCCCCCGGCCCCCCTGGCGTCACTGGTGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGA
GAAGGGCCGCACTGGAGCCAAGGGTGCCAAGGGCTATCAAGGACAGCTGGGTGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCAC
TCCAGGCCCTAAAGGGTCCCGGGGCAGCCTGGGACCAACGGGTGCTCCGGGACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTA
TGATGGACACAAAGGCATTGTGGGACCCCTTGGACCTCCTGGACCAAAAGGCGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGG
GCCCCCTGGGCCACCTGGAGATCGGGGCCCTGTGGGTGATCGAGGAGACCGCGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGG
TGTGCAAGGCCTCCGTGGAAAGCCAGGCCAGCAGGGCCAACCCGGGCATCCGGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGG
CGCAGAGGGACCAAAGGGAAAGCAAGGCAAGGCAGGGGCCCCAGGCCGGAGGGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGG
CGTGGTGGGGAGACAGGGCCTCGAGGGCATCGCTGGACCAGATGGGCTTCCTGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGG
AGACGATGGGGACCCTGGCCCCATGGGCCCTGCTGGGAAGAGAGGAAATCCAGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGG
ATTCAAGGGTGAGAGTGGGTTACCCGGACAGCTGGGTCCCCCTGGCAAGCGAGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGG
GGAGCCTGGGTCCAAAGGCCAGCCGGCTGACGGAGCCAGTGCAGCCGGAAGGAAAAGCACTGCGAGCAGGGAGCGCTTGAAGCGCAGCCA
GAAGAGCACCAAGGTGGAGGGCCCAGAGCCAGTGCCAGCCGAGGCCTCGCTGAGTGCCGAGCAAGGAACGATGACGGAGGTGAAGGTGAA
GACAGAGCTGCCCGATGACTACATCCAGGAGGTGATCTGGCAGGGCGAGGCCAAGGAGGAGAAGAAGGCGGTCAGCAAGGATGGGACCAG
CGACGTGCCTGCCGAGATCTGCGTGGTGATCGGCGGCGTCCGCAACCAGCAGACCCTTGGGTCTTACGAATGCGGAATCTGTGGCAAGAA
GTACAAGTATTACAACTGCTTCCAGACCCACGTGCGGGCGCACCGAGACACCGAAGCCACCTCAGGGGAGGGAGCCTCCCAAAGCAACAA
TTTCAGGTACACATGTGATATCTGCGGGAAGAAGTACAAATACTACAGCTGTTTCCAAGAGCACCGAGACCTGCACGCAGTGGATGTGTT
TAGTGTGGAAGGGGCCCCTGAGAACCGGGCAGACCCCTTCGACCAAGGTGTCGTGGCCACGGACGAGGTGAAGGAGGAGCCCCCGGAGCC
ATTCCAGAAAATCGGGCCAATGAACAATATTACATCAGACATTTTTAAGAAGAAAGAAGTTAGGCAGTGCCAAAAGAGAGAAACTGGCAA
TTACACCTGTGAATTCTGCGGCAAACAGTACAAGTACTACACTCCCTACCAGGAGCATGTGGCCTTACACGCCCCCATCAAAAGCGCTTT
CAGTCGGAGAGTAGAAGGCAAAGCACAAAACCACTTTGAAGAGACGAACAGCAGTTCGCAGAACTCCAGCGAACCCTACACCTGCGGCGC
CTGTGGGATCCAGTTCCAGTTCTACAACAACCTGTTGGAGCACATGCAGTCCCATGCAGCTGACAATGAAAACAACATTGCCTCCAACCA
GTCCCGATCGCCACCTGCTGTTGTAGAAGAGAAGTGGAAACCTCAGGCCCAGAGGAACAGTGCCAATAACACCACTACCAGTGGTTTAAC
ACCCAACAGCATGATCCCCGAAAAGGAGCGGCAGAACATCGCAGAGCGGCTGTTGAGGGTCATGTGTGCCGACCTGGGTGCACTGAGCGT
GGTCAGCGGGAAGGAGTTCCTGAAGTTGGCCCAGACCTTAGTAGACAGTGGTGCCCGCTATGGGGCCTTCTCGGTCACTGAAATCCTGGG
CAACTTCAACACGCTGGCGCTGAAGCACCTGCCACGCATGTACAACCAGGTGAAGGTGAAAGTGACCTGTGCCTTGGGCAGCAATGCCTG
CCTAGGCATCGGTGTCACCTGCCACTCCCAGAGTGTTGGCCCTGACTCCTGCTACATCCTCACAGCCTACCAGGCCGAGGGCAACCACAT
CAAGAGCTATGTGCTTGGTGTGAAGGGTGCGGACATTCGCGACAGCGGTGACCTTGTGCACCACTGGGTGCAGAACGTGCTGTCGGAGTT
CGTGATGTCGGAGATCAGGACAGTGTACGTGACGGATTGCCGGGTGAGCACGTCCGCCTTCTCCAAGGCCGGCATGTGCCTTCGCTGCTC
AGCCTGTGCCTTGAACTCGGTGGTGCAGAGCGTGCTGAGCAAGCGGACACTGCAGGCCCGCAGCATGCACGAGGTCATCGAGCTGCTCAA
CGTGTGCGAGGACCTGGCGGGCTCCACGGGCCTGGCCAAGGAGACCTTCGGGTCGCTGGAGGAGACGTCTCCACCACCCTGCTGGAACTC
GGTGACGGACTCACTGTTGCTGGTGCATGAGCGCTATGAGCAGATCTGCGAGTTCTACAGCCGGGCCAAGAAGATGAACCTCATCCAGAG
CCTCAACAAGCACCTGCTCAGCAACCTGGCGGCCATCCTGACGCCGGTGAAGCAGGCAGTCATCGAGCTGAGCAACGAGAGCCAGCCCAC
CCTGCAGCTGGTGCTGCCCACCTACGTCAGGCTGGAGAAGCTGTTCACGGCCAAGGCCAACGACGCAGGCACTGTCAGCAAGCTCTGCCA
CCTCTTCCTGGAGGCGCTCAAGGAGAACTTCAAGGTGCACCCGGCCCACAAGGTGGCCATGATCCTGGACCCGCAGCAGAAGCTGCGGCC
TGTGCCACCCTACCAGCACGAGGAGATCATCGGCAAGGTCTGTGAGCTCATCAACGAGGTGAAGGAGTCCTGGGCCGAGGAGGCCGACTT
CGAGCCCGCTGCCAAGAAGCCCCGCTCTGCTGCCGTCGAGAACCCCGCAGCTCAGGAAGATGATCGGCTAGGCAAAAATGAAGTGTACGA
TTACCTGCAGGAGCCCCTCTTCCAGGCTACCCCTGATCTCTTCCAGTACTGGTCGTGCGTTACCCAAAAGCACACAAAACTCGCCAAGCT
CGCCTTCTGGCTCCTGGCGGTTCCGGCCGTGGGCGCCAGAAGCGGGTGTGTAAATATGTGTGAACAAGCGCTTCTAATCAAACGGAGGCG
GCTGCTCAGTCCAGAAGATATGAATAAACTCATGTTTCTGAAATCCAACATGCTTTAAGACTTGACTTCGGGGGAAAAAAAAAGAAAAAG
AGAAGATAACATTAGAAAAAAACCACACAACACTGTCACAAAGAAAAGGAATTTAAGTTCTAAACACTGTGGACCTCATTATAAATGCCC
CCTGGAAACTTAAGTGCTTTTTTTATATGTGTGTGTGTGCGTGTATGTACACAGCCACACGTGTGTGCACGTGTCTGAACACGTGCTGTG
GTTGTGGGGGTGTGGGGGGGTCTCTGTGCTCATCTCCATGGCCAGAGAAACTTTGCACACACGCACACACACACACACACACACACACAC
ACACACGACCCTGGTGCGTGTACATACGCCTGTGCTTGGACGGGTGTGCATTGAACTGGGCGTGTCAGGAAAGCTGAGCGATTGGGAAAG
AGGGAGATGTTTCACCTCCTTTTCTCAGTAAGGGGGCTTTAGAAGACTCCGCTTTCAGGTGTGCAGATTGGCAGAAAGCTGATGTTGTGA
AATGTTCAGGCAGCTGAGATCTGAAGTGACTTGACGCTCTCTGTCCTTCACCCCGGTCCTCCTTTTCCCTCTTTGACCCTCTTCCAGCCC
TCCTACCCTCCTGATCCCATTGTGCACCCCCCCACACACTCGGCTGCTCTGCTGTGGACTCTCCACACTGCATCAGATGGACGGTTTCTG
CACTGGACTTTGTTTCTTGTTCACCTTCAGGGCATTGAGCTGCTGCCTTTGAGATACCCCTTGGGTGTCCCGGGGCAGCCGCCTTAGAAA
CACACCTATCTATCTCCCCAAATCAGGAAAGGAGACTTAAAGAGTATAAAGCTGACATTTTGCTTTTTAATATAAGAGAGGAGAAAAAGA
CATTTTTCAGAGAAGTATAGATACTGTCTCCACTCCCTAATAATTTCTCTCCCTAACATTTTAGCAATTTTTACCTTGTTTGGGGGTTCA
TTTTGTTTCTTCAGATTTGATTTAGACTCTGCTAGGAGGCACTGAATGTCTATAACTTATGTTTTGGAGTTTTGTTTTTTTACTTGCCCC
TTTTGTTCCTCAAGTCACACTGTAAACTAGCTCATCTCTGTGGTGTACTCAGTATCCTACAGTCTTTCTTGGCCTTCCCTGTACAGTTCA
GTTTTCACATATTCGAACGGCCAAGACCAGGTTCTTGGCTGTGCTATTTGGAGACCAGGCGTTGGGGAGGATTCACGGGTTCCACAGCTG
CGGGGTTTGGTGGCCGTAGGGGAAGCAGTGGTTTGGGAGTTCTGAATGTAAGCGCCAGAGCTGCCCTCCTGGTCCGCTGTGCGTGGTACC
CAGTGTGCATCACACTACTCACCCCCTCCCGGACCCTGGCAGTCCACAGCGACTCCGAAGTCAGCCCATAGTCACATCCACCACACCTCA
GACCTGCCACAGCCTCTCCTCACTTCCCAGGACCCTGAGGCTTCCAGGAGCTCTGCTGCCCACAGCCCTCGGGGTCCTCACTCACACCTC
CGACTTCCAGGACGGCAGTGAGCATGGTGCCTTGTGGCCCCAACAGTTGATGTTCCGAGGGTGGGATGGTGTTTGGCCATGTTCGACTCG
ATGCTGTGAAAGATGTCTTCAGGCTTTTCTCTCCTGTTCCCCCAGCTGTGAGCAAATTAGGTTCTACACACACAGTTCGGATGCCAAGGG
TGACACCCCATTCCCTTCACAAGAGGCGGTTCTGTCACAAATCAGCACTCCACCCCCACCACACCTCTCAGTGAATGAAGTGCTGGTGGT
CTCACTCCCCTGGTGACCCTTAGCCGTGGGATGGGGTGGTTACACTAAGGCTTCAAGCTGAGAATGGCCATCATGGCGGGAGGCTGTTTG
CAAAGGCACCTTCTGTCATCCTGGGGTTGGCTAAGTCAACTCCACCCCTTCCCAATAATAAAGCATCACTCAACTGTGAGATACCTCGAC
TACAAAAAGCACTGTACCACAGCCCTCTCCCCCTGGGTCCATGACAGGAGCAGGGAGTAAAGTTGATTGCAAACCTCATGAAGGCTTAGG
ATCATGGACCTGGAACATAGTGTTTGGGGGCCAAGCCTGCACACTTTGCCTCATGAGAACTCACCCAGCTCTCCCCTTGAAACTTGGACA
CACTGAAATGGATCAAAGTGGGCCATTTCCACATTTGCTCCAGCAAACTGTGGTCTCAGGAACTACCATGCCATTTCCTCTCCTGGAGAA
GTTCTAGGTATTACCTCCACAACATTTCCAACTGGGGGACTGAGCCCACTTATCAGAGAAGAGCCGCCATCCACACTGGAGCAGGAACAG
GGAGAAATCCAGACAGGAACCTCATGTCACTTCCTAGGGAATATGGGAAGAAACATCAGCAGACTTTATGATGTCAGTTGGGCCTTTGGA
GGCATTCTGGAAGGTGGCCTCAGCATCACTGATGATTGACAGATGCTACAGCAAAAGGTCCCTCTAGCGTTGCTTGACTGCTGGGGAAGG
GACAGTGACCGGCACTTTGACCCACACAAGGATAGGAGCTGCCTACTTTGTGTGGTAGGTGAGAGCAGAGCCTGGGAGCCCATCCTCCCT
CTACTTGGAGCAAAGTTGTGCTGGTGATGCCCCATTATTGGGCCAGTTGATTAGAAAATAGGCATTTCACTTTCTTGGAAAGCCATCGGA
CTAAGCCCAGATGTGCATTTAGAGCACTCAGCATTCTTCTCTTTGAAGCATGGGATGTCTGTCCTCCAGGAAGAGATTTGATCTTAGGTT
GTTACCTCCCTTTCACTTCTTTTCCACCTCAATTCAATACTTAGGGGTTGGCTTGCCTCTGCAGGTTTGATGTGAATGCCACTGGGTACT
CAGAAAGCTGTCCTCTGGGGCTGCCTTGTCCAGTTAGATAACAAGATAGCAGATGATTGTTTCTTGCAACCTCTGGTTCCCTCCGGAAAC
TGGTGTCACCAACAGGAAAGGCTGTACCAAGGTGCCCTCTTCTCAGACAGGCTGTTCTCAGAGTGCAAATCCTGCTGCAACTAACAGCTT
AATAAAACCCAAAGATCTCACAGGTCCAGCCACTGGCCCCTTTATCTCCAACAATATCCACCTCACCAAATTCTAGTTCAGCCAAAGGAT
TGAGACAGGCTCTTCCAGTTCATCTCCTGGTGTCCAGCCTGACCTTCACATCTGGAAGGATTTTGTCGTCTGCCTCCCAGTTCTGGGTCC
ACTGTAGGTCTTTCCATCACAAGCCTTTGGGGGATCTGGGACCAGGAATTTGGGCCGTTTCTACCATATTCTCAGCAGCCTAAGGTGGTG
GCCTGCTGATGTGGAGACTACTCACCTTGAGCCATGTGGTCCCCAGGACAGAAATGGCCTTTGTTTTGACATACATGGACCCAAAAGGGG
AGGTGAAGAAAACACACCTCCACCTGGCAAGTTTTTCTCCCTCATCTGAGGTCAGTTGCTTCACCAACAAAGCCCAAGCCAAGAACTGCA
GCGTTGAGGGTTGTCCCTCGGAGTGGAGTAGCCCAAGGAATCTCAGGTCCACCAAGAGCATTGGTACCATCTGGGCCACGGGTGGATGCC
TTTGTTCTGGCACAGTTCTCCACTTCCCGATTCCTGGCTCAGCCAGCCAGGCCTCCCTCTAATGGCATTTAGTAACCAGGAAACAAAACA
CATGCCACCTGAGCAAAACTGCCTGCACTTCATCTCTGGAGGTTCGCTGCACAGAGGCCACCTGCCGCATCACCAGTGAGGAAGCTTTGC
CACCATCCTGCTTGGCAGCTTCACACTTGACATCTGAGGATTGGTTTTTGGCTGGAAAAAGGGTACCAGGGTTTCCTGGCAAGGACAGGA
GAGCAGTGCAGTGACACAGATGAGAAGCTGTGAGTCTCCAGGATTCAAGGAAGCCACCAGGTGTGCAGGCTGGGAAGAGACATCTCTTTC
AGTTTGACCCTTTATCTCCTGCACTTTTAAAGAAACACCAGAGAAAAAATCTACAAGGCGTGTTTCCACTGAAGCTGAACCTCTGCCTTT
AGGAGTCCCCTATATTTGAGCAAGGCCACCTGCTTCCCCTGGACTTGAGCTGGACTCCTTGAAGAGTGGGCTTCTGGAGAGATGTTAGGA
ATATAGCACATGCTCTCTGGGGGCCACAGGGTCATTGGGAAGGTTTGAAATGAAGATGGGATGTGGCTGGAACAGCCTGTGAGATGGCTC
CATTGGGGACACTCCCCTCATCTTGTCATCACGATGGATATGCTGGAAGAGGAGGTGTCCCAGTGAGCCGCCCGAAGTTCATAGCTTTGC
CCTCGCCTTGGCAACAGCGGCAATGCCTCTATCTCTGGGATGCATCTTAAGGAGGGCTCCTAACAAGGCCGATGATTTAGACAGAACAAG
AGACTAAGTAAGGTCCGGCTATCCCGTGGAGCCAGTAGTAGGTGGGAGCTCCTGTCCCCGCCAGCCCTGCTCCAGCCCCCGTGTCCAGCT
GGGCCAGTGGAAGAACTGGGAAGGAGGAAGCCCCTCCCTTTCACTGTGGCTAATGTTTGCTAGGCCAGTTATGGTGAACCAATGATACAG
TGTTTTCCCTCTTAACGTTCCCCTCCTGGTTTTGCCTTTTCAGGGTTTTCTGGGGGATTTTGTTGTAGTAGTTGCTTTTCTTCCTCTCTC
ATTTGGGTTTGAGGATTGTGGTCGGGGGAGCCCTGGCTTTCACCAAAGGAGCCCAGTGGTTTCTGTGGAAGAGGCGCCCACTCCCACTTT
AATGAGGGTGAAGATTGTCAGGTCACTGTTTGACATATTCATGCCCCGTCCCTTCCCCCCCCACCCCCCCGCCCACCCACCACGGGTGTC
GCTTTAAAGAGTCAATTCTTGTACAGAGAAGGATTTGCTAGGTTTGCATTTGGGTGTTAGCATCACGACCCACGAGGGCCCTGCCCAACC
GTGCGTCCCATGGGGCACCTTGACTCTTCAAACCAAAATTCCTTAAAGGGGCACAGCCCAGCCTTGTCCGCAACCTCAGGGGCCTGGGAT
TCCTGTGGCGCTTCCTGAATTCCAGGTTGGCACAGATGATGAGGTCTGAGACCAGCCGGAAGGAGGGGCTCCTGCCATAACCCAGGTGCC
AGCCGGTCTCCGCCTAGGACCTTCCCTCCCGCCCAGCCAGGGTGGGCGGCATCCTACGCGGTGAAACGAGCTCATGGACTGACCCGGGGC
TGGGCCTCGCCAGCCAGGAGAGAGCGAGGGCCGCACGGCAGGGCTGGCCCAGGCAGCTCGTCCAGGGCCATTCAGATCCCAAGCATCAGG
AAATCATTTTGTACAACCACCCGAAGCAGAGATATTTTTTAAGAAGCGTAAATTATTTTCAGTTGTTTTCTGATCCTGCCTTTTTCTTTT
CCCCACAACTTCACGCCAGTGAGTCGTTCACATCAGGTAAATCTTGAGAAAGCCTTGGTGCCCTCCTCCCCACCCCCCACTCAGTAACCA
CGTGCGTGCACCCCCGCATCCTTTCTCAGTAGTTAAGACGTTCTAGGCAATACCATAGACACATCTGACTGTGTCTCTCTCTTTGAGTGC
AAGAAACTCAAGTCATCTTAAAAAAAAAAAAATACAAAAAAAATTTACAAAAAAACAAACACAAAAAAAATATCTTTTTTAGGCCAGAGT
TTTCTACAGGTATTAATGAATATTTTTCTTAATCCTTATAAGTTTTATGTGTTTAATATTTCTTAATACCGGTAGCATTAATTTATACTT
TTGTAGCAACACAATATTTTTATAAACAGCCGGTGCTTGGCTCAAGTCTTCACGAGGGGTTTAGGCAGGGCCATCTTGGGGACCCTGTGT
ACCATGTACTGTATTTAAAAAAAAAAAAAGTTACCTATTGTCACACTTGCTGTGTTAATTAACAAAAGATGTTGTGTGCGGTCTCCTGTA
TCGGTGTGGATCCAACAGCTCTCCAGGGAGTCACATTGCATGGGGGTTGAGTTGACGGTTCTTGTGATATGTAAACCCCCGAGACCAAAC
TTGAGGGTTTATTTAGGGTTTTCTGTTTGTCCTTTGGGTTTTTGTTTCACTTTGTTTTGGTGCCGTTTCTCCATTTACAGCCAAATCAGT
TTCATGATGTTCAAAACATTTACTGATGTCAAATGGAGGAAAGGAACAGAAAAAAAGATTTTTACAAAGTAATAAAATTTAAAACTGAGC
TGTTTAATGTTGCTGTTTTTACCTGTCTGTTCTTGTCCAAAAGTGGAACATTCCCAGGGAGAAGAGGAAGGTTCCACTCGGTTCTTTAAG
TCGCCAAAAGCCCCAGCCCGGGATTCAGTACCTCCCCTGCCCCCCGAATTCTTGCAGCACTATTTCCCAGTTGGTTGATGCCAAGGCAAA
AAGATAACTTTTAACAGTTAGAGAGGATCAGTTGCTTAAATGATTTCATGTCAGTGTTGTATTTATGGTTTTACAATAAAACAACCTTTA

>18271_18271_1_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731396_ENST00000288466_length(amino acids)=2378AA_BP=635
MGAGSARGARGTAAAAAARGGGFLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVI
PAALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVP
VLLPFHRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLE
NLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKIT
ATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSS
KKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSE
ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPK
GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP
GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL
GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI
GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPV
GEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSR
GLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDL
GPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAK
GYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP
VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI
AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPAD
GASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVI
GGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEATSGEGASQSNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVEGAPENRA
DPFDQGVVATDEVKEEPPEPFQKIGPMNNITSDIFKKKEVRQCQKRETGNYTCEFCGKQYKYYTPYQEHVALHAPIKSAFSRRVEGKAQN
HFEETNSSSQNSSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNTTTSGLTPNSMIPEKER
QNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQ
SVGPDSCYILTAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFSKAGMCLRCSACALNSVVQS
VLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLSNLA
AILTPVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKVHPAHKVAMILDPQQKLRPVPPYQHEEII
GKVCELINEVKESWAEEADFEPAAKKPRSAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAV

--------------------------------------------------------------
>18271_18271_2_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731396_ENST00000374126_length(transcript)=7861nt_BP=4975nt
CGGCGGGGAGGCAGCTTCCACCGCCCTCCGCGCGCCCTCACCCGGCCTTGCTCTGCCTCCGGGGACCGCCAGCAGCCCGCCTCCAAAAGT
TTGATCATCTCTCTCTCTCTTTTTCTTGCTTCTTCTTCCTTTTTGGTGGAAGCAGAAAAGGACCGAGGCAGGGGCGAGCGCGGCGCCCGG
ACTCCTGGGACCATGGGCCTGGCGCGGGCGCCCGCGGGGCCCCAGCCGCGCTGCCTGCCTGCTCGGGCGCCCCTGGGCGCGGGGCTGCGC
TGGGGGCGCGGGGGCCGCGCGCTCTAAGCCGGCCTGGCGCGGCGGGGCGGGGGGCTGGCGGCCCCATGGGGCGCGCCCACACTTGCCCCC
CGGGCTCGGGAGCATGAAGTAGGGGCCTGCCATGGGAGCGGGATCGGCGCGGGGGGCCCGAGGCACAGCGGCGGCGGCGGCGGCGCGCGG
GGGGGGGTTTCTCTTCTCCTGGATCTTAGTCTCGTTTGCCTGTCACCTGGCCTCCACCCAAGGAGCTCCTGAAGATGTGGACATCCTCCA
GCGGCTGGGCCTCAGCTGGACGAAGGCCGGGAGCCCTGCACCCCCGGGAGTCATTCCTTTCCAGTCGGGCTTCATCTTTACGCAGCGGGC
CCGGCTCCAGGCTCCCACGGGCACCGTCATTCCTGCCGCCTTGGGCACAGAGCTGGCACTGGTGCTGAGCCTCTGCTCCCACCGGGTGAA
CCATGCCTTCCTCTTCGCTGTCCGCAGCCAGAAACGCAAGCTGCAGCTGGGCCTGCAGTTCCTCCCCGGCAAGACGGTCGTCCACCTCGG
GTCCCGGCGCTCAGTGGCCTTCGACCTCGACATGCACGACGGGCGCTGGCACCACCTGGCCCTCGAGCTCCGAGGCCGCACAGTCACTCT
GGTGACTGCCTGCGGGCAGCGCCGGGTGCCTGTCCTGCTGCCTTTCCACAGGGACCCTGCACTCGACCCTGGGGGCTCCTTCCTCTTTGG
GAAGATGAACCCGCATGCAGTCCAGTTTGAAGGTGCTCTCTGCCAGTTCAGTATCTACCCTGTGACGCAGGTCGCTCACAATTACTGTAC
CCACCTGAGGAAGCAGTGTGGACAGGCTGACACGTACCAGTCCCCACTGGGACCTCTCTTCTCCCAAGACTCTGGCAGACCTTTTACCTT
CCAGTCCGACCTCGCCCTGCTAGGCCTGGAGAACTTGACCACTGCCACACCAGCCCTGGGGTCACTGCCAGCAGGCAGGGGACCCAGGGG
GACTGTGGCACCCGCCACGCCCACCAAGCCCCAAAGGACTAGCCCCACAAACCCTCACCAGCATATGGCGGTGGGAGGCCCAGCCCAAAC
CCCGCTGCTACCTGCCAAGCTGTCAGCCAGTAACGCACTTGATCCCATGCTCCCAGCCTCTGTTGGCGGCTCTACCAGAACGCCTCGCCC
TGCGGCCGCTCAACCATCACAGAAGATCACAGCCACCAAAATCCCCAAAAGCCTCCCTACCAAGCCTTCGGCCCCTTCTACTTCAATTGT
GCCCATCAAAAGCCCCCATCCTACCCAGAAAACAGCTCCATCTTCATTTACAAAGTCAGCCCTACCCACTCAGAAGCAAGTGCCACCTAC
TTCCCGTCCAGTTCCTGCCAGAGTCTCCCGTCCCGCAGAGAAGCCCATCCAGAGGAACCCGGGAATGCCCAGGCCCCCACCGCCCAGCAC
CCGGCCCCTACCTCCTACCACCAGCTCCTCTAAAAAACCCATTCCCACACTAGCTCGGACTGAGGCCAAGATAACCAGCCATGCCAGTAA
GCCGGCCTCTGCCCGCACCAGCACCCACAAACCTCCCCCATTTACTGCTTTATCCTCATCTCCTGCCCCTACTCCTGGTTCTACCAGGAG
TACTCGGCCACCAGCCACGATGGTACCTCCAACTTCGGGCACCAGCACTCCCAGAACAGCACCTGCCGTCCCCACTCCTGGCTCAGCTCC
CACTGGAAGCAAGAAGCCCATTGGATCGGAAGCCTCAAAGAAAGCCGGACCCAAGAGCAGCCCCCGGAAGCCTGTCCCCCTCAGACCTGG
GAAGGCAGCCAGGGATGTCCCCTTGAGCGATCTGACAACCAGGCCTAGCCCCAGACAGCCCCAGCCCAGTCAGCAGACCACCCCGGCCCT
GGTATTGGCCCCGGCGCAATTCCTGTCCTCCAGCCCCCGGCCCACGAGCAGTGGCTATTCGATCTTCCACCTGGCAGGATCTACGCCTTT
CCCTCTGCTGATGGGGCCTCCGGGACCCAAGGGAGACTGTGGCTTGCCGGGTCCCCCTGGGCTACCTGGGCTACCTGGAATCCCTGGTGC
ACGTGGGCCTCGGGGTCCTCCTGGGCCTTATGGAAATCCAGGTCTCCCCGGCCCTCCTGGAGCCAAAGGACAGAAAGGGGACCCAGGGCT
CTCACCAGGAAAGGCCCACGATGGGGCAAAGGGTGACATGGGCTTGCCTGGGCTCTCCGGGAATCCAGGACCTCCGGGACGAAAGGGACA
CAAGGGCTATCCTGGACCGGCAGGGCACCCCGGAGAACAGGGGCAGCCAGGACCTGAGGGCAGCCCAGGGGCCAAAGGTTACCCTGGCAG
GCAGGGGTTACCTGGACCGGTAGGAGATCCCGGCCCCAAAGGCAGCAGGGGCTACATTGGGCTCCCAGGGCTCTTCGGCCTGCCAGGGTC
TGATGGAGAACGAGGCCTGCCTGGCGTTCCTGGCAAGAGGGGCAAGATGGGTATGCCGGGGTTTCCTGGAGTCTTTGGGGAAAGAGGCCC
TCCTGGACTGGATGGAAATCCTGGAGAACTGGGCCTGCCAGGCCCCCCTGGAGTCCCCGGCCTCATTGGTGACTTAGGAGTGTTGGGTCC
GATTGGCTACCCGGGACCCAAGGGCATGAAGGGACTGATGGGCAGCGTGGGGGAGCCCGGACTGAAAGGTGATAAGGGTGAACAAGGGGT
TCCAGGTGTGTCAGGAGATCCCGGATTCCAAGGAGACAAGGGGAGCCAGGGGTTGCCAGGGTTCCCCGGTGCACGGGGGAAGCCAGGGCC
TCTGGGCAAAGTCGGAGACAAAGGATCCATTGGGTTTCCCGGGCCCCCTGGACCCGAGGGATTCCCAGGAGACATCGGCCCCCCTGGCGA
CAATGGCCCAGAAGGCATGAAGGGTAAGCCTGGAGCCCGAGGCCTGCCGGGACCCCGTGGGCAGCTGGGGCCCGAGGGAGATGAGGGACC
CATGGGGCCGCCAGGGGCCCCTGGCTTGGAGGGTCAGCCTGGCAGGAAGGGGTTTCCTGGGAGGCCCGGCCTGGATGGCGTGAAGGGGGA
ACCAGGGGATCCTGGTCGGCCGGGGCCTGTGGGAGAGCAGGGATTTATGGGATTCATTGGTCTGGTCGGGGAGCCAGGAATCGTGGGAGA
AAAGGGTGATCGTGGCATGATGGGACCCCCAGGCGTGCCTGGACCCAAGGGGTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGAC
CCCTGGAGAGCCTGGACCCCAGGGTCCTCCAGGATCTCGAGGCCCACCAGGCATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACC
GGACGGACCAGCTGGGGAGCAAGGGTCCAGGGGCCTGAAGGGCCCTCCAGGACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGT
GGCTGGTGAGCGAGGCCACTTGGGCTCGAGAGGCTTTCCTGGCATCCCGGGTCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGA
ACCGGGCCCTCAGGGACCCCAGGGGCCAATTGGGCCTCCAGGAGAGATGGGACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCT
TCCTGGGGAAGCCGGGATGAAGGGTGACCTTGGACCCCTGGGCACTCCTGGGGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCT
TGAGGGTGACAGTGGCCCCATGGGACCTGATGGGCTGAAGGGGGACAGGGGAGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCA
GGAAGGGCTGATGGGTGAGGACGGGCCCCCCGGCCCCCCTGGCGTCACTGGTGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGA
GAAGGGCCGCACTGGAGCCAAGGGTGCCAAGGGCTATCAAGGACAGCTGGGTGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCAC
TCCAGGCCCTAAAGGGTCCCGGGGCAGCCTGGGACCAACGGGTGCTCCGGGACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTA
TGATGGACACAAAGGCATTGTGGGACCCCTTGGACCTCCTGGACCAAAAGGCGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGG
GCCCCCTGGGCCACCTGGAGATCGGGGCCCTGTGGGTGATCGAGGAGACCGCGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGG
TGTGCAAGGCCTCCGTGGAAAGCCAGGCCAGCAGGGCCAACCCGGGCATCCGGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGG
CGCAGAGGGACCAAAGGGAAAGCAAGGCAAGGCAGGGGCCCCAGGCCGGAGGGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGG
CGTGGTGGGGAGACAGGGCCTCGAGGGCATCGCTGGACCAGATGGGCTTCCTGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGG
AGACGATGGGGACCCTGGCCCCATGGGCCCTGCTGGGAAGAGAGGAAATCCAGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGG
ATTCAAGGGTGAGAGTGGGTTACCCGGACAGCTGGGTCCCCCTGGCAAGCGAGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGG
GGAGCCTGGGTCCAAAGGCCAGCCGGCTGACGGAGCCAGTGCAGCCGGAAGGAAAAGCACTGCGAGCAGGGAGCGCTTGAAGCGCAGCCA
GAAGAGCACCAAGGTGGAGGGCCCAGAGCCAGTGCCAGCCGAGGCCTCGCTGAGTGCCGAGCAAGGAACGATGACGGAGGTGAAGGTGAA
GACAGAGCTGCCCGATGACTACATCCAGGAGGTGATCTGGCAGGGCGAGGCCAAGGAGGAGAAGAAGGCGGTCAGCAAGGATGGGACCAG
CGACGTGCCTGCCGAGATCTGCGTGGTGATCGGCGGCGTCCGCAACCAGCAGACCCTTGATGGAAAAGCGCCCGAAGGCAGCCCCCACGG
TGGATCTGTGCGAAGCCGGTATTCAGGGACCTGGATTTTTGACCAAGCATTGAGATATGCATCTGGGTCTTACGAATGCGGAATCTGTGG
CAAGAAGTACAAGTATTACAACTGCTTCCAGACCCACGTGCGGGCGCACCGAGACACCGAAGCCACCTCAGGGGAGGGAGCCTCCCAAAG
CAACAATTTCAGGTACACATGTGATATCTGCGGGAAGAAGTACAAATACTACAGCTGTTTCCAAGAGCACCGAGACCTGCACGCAGTGGA
TGTGTTTAGTGTGGAAGGGGCCCCTGAGAACCGGGCAGACCCCTTCGACCAAGGTGTCGTGGCCACGGACGAGGTGAAGGAGGAGCCCCC
GGAGCCATTCCAGAAAATCGGGCCAAAAACTGGCAATTACACCTGTGAATTCTGCGGCAAACAGTACAAGTACTACACTCCCTACCAGGA
GCATGTGGCCTTACACGCCCCCATCAGTACTGCCCCCGGGTGGGAGCCACCGGATGATCCAGACACGGGCTCTGAGTGTTCACATCCAGA
GGTCTCCCCATCTCCACGCTTCGTGGCAGCGAAGACCCAGACGAACCAGTCGGGGAAAAAAGCTCCGGCCTCCGTGGTCCGATGTGCCAC
CCTCTTACACCGCACCCCTCCAGCCACCCAAACCCAGACGTTCCGCACTCCAAATTCGGGATCTCCGGCGAGCAAGGCAACCGCAGCAGA
AAGCGCTTTCAGTCGGAGAGTAGAAGGCAAAGCACAAAACCACTTTGAAGAGACGAACAGCAGTTCGCAGAACTCCAGCGAACCCTACAC
CTGCGGCGCCTGTGGGATCCAGTTCCAGTTCTACAACAACCTGTTGGAGCACATGCAGTCCCATGCAGCTGACAATGAAAACAACATTGC
CTCCAACCAGTCCCGATCGCCACCTGCTGTTGTAGAAGAGAAGTGGAAACCTCAGGCCCAGAGGAACAGTGCCAATAACACCACTACCAG
TGGTTTAACACCCAACAGCATGATCCCCGAAAAGGAGCGGCAGAACATCGCAGAGCGGCTGTTGAGGGTCATGTGTGCCGACCTGGGTGC
ACTGAGCGTGGTCAGCGGGAAGGAGTTCCTGAAGTTGGCCCAGACCTTAGTAGACAGTGGTGCCCGCTATGGGGCCTTCTCGGTCACTGA
AATCCTGGGCAACTTCAACACGCTGGCGCTGAAGCACCTGCCACGCATGTACAACCAGGTGAAGGTGAAAGTGACCTGTGCCTTGGGCAG
CAATGCCTGCCTAGGCATCGGTGTCACCTGCCACTCCCAGAGTGTTGGCCCTGACTCCTGCTACATCCTCACAGCCTACCAGGCCGAGGG
CAACCACATCAAGAGCTATGTGCTTGGTGTGAAGGGTGCGGACATTCGCGACAGCGGTGACCTTGTGCACCACTGGGTGCAGAACGTGCT
GTCGGAGTTCGTGATGTCGGAGATCAGGACAGTGTACGTGACGGATTGCCGGGTGAGCACGTCCGCCTTCTCCAAGGCCGGCATGTGCCT
TCGCTGCTCAGCCTGTGCCTTGAACTCGGTGGTGCAGAGCGTGCTGAGCAAGCGGACACTGCAGGCCCGCAGCATGCACGAGGTCATCGA
GCTGCTCAACGTGTGCGAGGACCTGGCGGGCTCCACGGGCCTGGCCAAGGAGACCTTCGGGTCGCTGGAGGAGACGTCTCCACCACCCTG
CTGGAACTCGGTGACGGACTCACTGTTGCTGGTGCATGAGCGCTATGAGCAGATCTGCGAGTTCTACAGCCGGGCCAAGAAGATGAACCT
CATCCAGAGCCTCAACAAGCACCTGCTCAGCAACCTGGCGGCCATCCTGACGCCGGTGAAGCAGGCAGTCATCGAGCTGAGCAACGAGAG
CCAGCCCACCCTGCAGCTGGTGCTGCCCACCTACGTCAGGCTGGAGAAGCTGTTCACGGCCAAGGCCAACGACGCAGGCACTGTCAGCAA
GCTCTGCCACCTCTTCCTGGAGGCGCTCAAGGAGAACTTCAAGGTGCACCCGGCCCACAAGGTGGCCATGATCCTGGACCCGCAGCAGAA
GCTGCGGCCTGTGCCACCCTACCAGCACGAGGAGATCATCGGCAAGGTCTGTGAGCTCATCAACGAGGTGAAGGAGTCCTGGGCCGAGGA
GGCCGACTTCGAGCCCGCTGCCAAGAAGCCCCGCTCTGCTGCCGTCGAGAACCCCGCAGCTCAGGAAGATGATCGGCTAGGCAAAAATGA
AGTGTACGATTACCTGCAGGAGCCCCTCTTCCAGGCTACCCCTGATCTCTTCCAGTACTGGTCGTGCGTTACCCAAAAGCACACAAAACT
CGCCAAGCTCGCCTTCTGGCTCCTGGCGGTTCCGGCCGTGGGCGCCAGAAGCGGGTGTGTAAATATGTGTGAACAAGCGCTTCTAATCAA
ACGGAGGCGGCTGCTCAGTCCAGAAGATATGAATAAACTCATGTTTCTGAAATCCAACATGCTTTAAGACTTGACTTCGGGGGAAAAAAA

>18271_18271_2_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731396_ENST00000374126_length(amino acids)=2471AA_BP=635
MGAGSARGARGTAAAAAARGGGFLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVI
PAALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVP
VLLPFHRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLE
NLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKIT
ATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSS
KKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSE
ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPK
GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP
GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL
GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI
GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPV
GEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSR
GLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDL
GPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAK
GYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP
VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI
AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPAD
GASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVI
GGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATSGEGASQSNNFRYTCDIC
GKKYKYYSCFQEHRDLHAVDVFSVEGAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIST
APGWEPPDDPDTGSECSHPEVSPSPRFVAAKTQTNQSGKKAPASVVRCATLLHRTPPATQTQTFRTPNSGSPASKATAAESAFSRRVEGK
AQNHFEETNSSSQNSSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNTTTSGLTPNSMIPE
KERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTC
HSQSVGPDSCYILTAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFSKAGMCLRCSACALNSV
VQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLS
NLAAILTPVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKVHPAHKVAMILDPQQKLRPVPPYQHE
EIIGKVCELINEVKESWAEEADFEPAAKKPRSAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAV

--------------------------------------------------------------
>18271_18271_3_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731397_ENST00000288466_length(transcript)=13952nt_BP=4975nt
CGGCGGGGAGGCAGCTTCCACCGCCCTCCGCGCGCCCTCACCCGGCCTTGCTCTGCCTCCGGGGACCGCCAGCAGCCCGCCTCCAAAAGT
TTGATCATCTCTCTCTCTCTTTTTCTTGCTTCTTCTTCCTTTTTGGTGGAAGCAGAAAAGGACCGAGGCAGGGGCGAGCGCGGCGCCCGG
ACTCCTGGGACCATGGGCCTGGCGCGGGCGCCCGCGGGGCCCCAGCCGCGCTGCCTGCCTGCTCGGGCGCCCCTGGGCGCGGGGCTGCGC
TGGGGGCGCGGGGGCCGCGCGCTCTAAGCCGGCCTGGCGCGGCGGGGCGGGGGGCTGGCGGCCCCATGGGGCGCGCCCACACTTGCCCCC
CGGGCTCGGGAGCATGAAGTAGGGGCCTGCCATGGGAGCGGGATCGGCGCGGGGGGCCCGAGGCACAGCGGCGGCGGCGGCGGCGCGCGG
GGGGGGGTTTCTCTTCTCCTGGATCTTAGTCTCGTTTGCCTGTCACCTGGCCTCCACCCAAGGAGCTCCTGAAGATGTGGACATCCTCCA
GCGGCTGGGCCTCAGCTGGACGAAGGCCGGGAGCCCTGCACCCCCGGGAGTCATTCCTTTCCAGTCGGGCTTCATCTTTACGCAGCGGGC
CCGGCTCCAGGCTCCCACGGGCACCGTCATTCCTGCCGCCTTGGGCACAGAGCTGGCACTGGTGCTGAGCCTCTGCTCCCACCGGGTGAA
CCATGCCTTCCTCTTCGCTGTCCGCAGCCAGAAACGCAAGCTGCAGCTGGGCCTGCAGTTCCTCCCCGGCAAGACGGTCGTCCACCTCGG
GTCCCGGCGCTCAGTGGCCTTCGACCTCGACATGCACGACGGGCGCTGGCACCACCTGGCCCTCGAGCTCCGAGGCCGCACAGTCACTCT
GGTGACTGCCTGCGGGCAGCGCCGGGTGCCTGTCCTGCTGCCTTTCCACAGGGACCCTGCACTCGACCCTGGGGGCTCCTTCCTCTTTGG
GAAGATGAACCCGCATGCAGTCCAGTTTGAAGGTGCTCTCTGCCAGTTCAGTATCTACCCTGTGACGCAGGTCGCTCACAATTACTGTAC
CCACCTGAGGAAGCAGTGTGGACAGGCTGACACGTACCAGTCCCCACTGGGACCTCTCTTCTCCCAAGACTCTGGCAGACCTTTTACCTT
CCAGTCCGACCTCGCCCTGCTAGGCCTGGAGAACTTGACCACTGCCACACCAGCCCTGGGGTCACTGCCAGCAGGCAGGGGACCCAGGGG
GACTGTGGCACCCGCCACGCCCACCAAGCCCCAAAGGACTAGCCCCACAAACCCTCACCAGCATATGGCGGTGGGAGGCCCAGCCCAAAC
CCCGCTGCTACCTGCCAAGCTGTCAGCCAGTAACGCACTTGATCCCATGCTCCCAGCCTCTGTTGGCGGCTCTACCAGAACGCCTCGCCC
TGCGGCCGCTCAACCATCACAGAAGATCACAGCCACCAAAATCCCCAAAAGCCTCCCTACCAAGCCTTCGGCCCCTTCTACTTCAATTGT
GCCCATCAAAAGCCCCCATCCTACCCAGAAAACAGCTCCATCTTCATTTACAAAGTCAGCCCTACCCACTCAGAAGCAAGTGCCACCTAC
TTCCCGTCCAGTTCCTGCCAGAGTCTCCCGTCCCGCAGAGAAGCCCATCCAGAGGAACCCGGGAATGCCCAGGCCCCCACCGCCCAGCAC
CCGGCCCCTACCTCCTACCACCAGCTCCTCTAAAAAACCCATTCCCACACTAGCTCGGACTGAGGCCAAGATAACCAGCCATGCCAGTAA
GCCGGCCTCTGCCCGCACCAGCACCCACAAACCTCCCCCATTTACTGCTTTATCCTCATCTCCTGCCCCTACTCCTGGTTCTACCAGGAG
TACTCGGCCACCAGCCACGATGGTACCTCCAACTTCGGGCACCAGCACTCCCAGAACAGCACCTGCCGTCCCCACTCCTGGCTCAGCTCC
CACTGGAAGCAAGAAGCCCATTGGATCGGAAGCCTCAAAGAAAGCCGGACCCAAGAGCAGCCCCCGGAAGCCTGTCCCCCTCAGACCTGG
GAAGGCAGCCAGGGATGTCCCCTTGAGCGATCTGACAACCAGGCCTAGCCCCAGACAGCCCCAGCCCAGTCAGCAGACCACCCCGGCCCT
GGTATTGGCCCCGGCGCAATTCCTGTCCTCCAGCCCCCGGCCCACGAGCAGTGGCTATTCGATCTTCCACCTGGCAGGATCTACGCCTTT
CCCTCTGCTGATGGGGCCTCCGGGACCCAAGGGAGACTGTGGCTTGCCGGGTCCCCCTGGGCTACCTGGGCTACCTGGAATCCCTGGTGC
ACGTGGGCCTCGGGGTCCTCCTGGGCCTTATGGAAATCCAGGTCTCCCCGGCCCTCCTGGAGCCAAAGGACAGAAAGGGGACCCAGGGCT
CTCACCAGGAAAGGCCCACGATGGGGCAAAGGGTGACATGGGCTTGCCTGGGCTCTCCGGGAATCCAGGACCTCCGGGACGAAAGGGACA
CAAGGGCTATCCTGGACCGGCAGGGCACCCCGGAGAACAGGGGCAGCCAGGACCTGAGGGCAGCCCAGGGGCCAAAGGTTACCCTGGCAG
GCAGGGGTTACCTGGACCGGTAGGAGATCCCGGCCCCAAAGGCAGCAGGGGCTACATTGGGCTCCCAGGGCTCTTCGGCCTGCCAGGGTC
TGATGGAGAACGAGGCCTGCCTGGCGTTCCTGGCAAGAGGGGCAAGATGGGTATGCCGGGGTTTCCTGGAGTCTTTGGGGAAAGAGGCCC
TCCTGGACTGGATGGAAATCCTGGAGAACTGGGCCTGCCAGGCCCCCCTGGAGTCCCCGGCCTCATTGGTGACTTAGGAGTGTTGGGTCC
GATTGGCTACCCGGGACCCAAGGGCATGAAGGGACTGATGGGCAGCGTGGGGGAGCCCGGACTGAAAGGTGATAAGGGTGAACAAGGGGT
TCCAGGTGTGTCAGGAGATCCCGGATTCCAAGGAGACAAGGGGAGCCAGGGGTTGCCAGGGTTCCCCGGTGCACGGGGGAAGCCAGGGCC
TCTGGGCAAAGTCGGAGACAAAGGATCCATTGGGTTTCCCGGGCCCCCTGGACCCGAGGGATTCCCAGGAGACATCGGCCCCCCTGGCGA
CAATGGCCCAGAAGGCATGAAGGGTAAGCCTGGAGCCCGAGGCCTGCCGGGACCCCGTGGGCAGCTGGGGCCCGAGGGAGATGAGGGACC
CATGGGGCCGCCAGGGGCCCCTGGCTTGGAGGGTCAGCCTGGCAGGAAGGGGTTTCCTGGGAGGCCCGGCCTGGATGGCGTGAAGGGGGA
ACCAGGGGATCCTGGTCGGCCGGGGCCTGTGGGAGAGCAGGGATTTATGGGATTCATTGGTCTGGTCGGGGAGCCAGGAATCGTGGGAGA
AAAGGGTGATCGTGGCATGATGGGACCCCCAGGCGTGCCTGGACCCAAGGGGTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGAC
CCCTGGAGAGCCTGGACCCCAGGGTCCTCCAGGATCTCGAGGCCCACCAGGCATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACC
GGACGGACCAGCTGGGGAGCAAGGGTCCAGGGGCCTGAAGGGCCCTCCAGGACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGT
GGCTGGTGAGCGAGGCCACTTGGGCTCGAGAGGCTTTCCTGGCATCCCGGGTCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGA
ACCGGGCCCTCAGGGACCCCAGGGGCCAATTGGGCCTCCAGGAGAGATGGGACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCT
TCCTGGGGAAGCCGGGATGAAGGGTGACCTTGGACCCCTGGGCACTCCTGGGGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCT
TGAGGGTGACAGTGGCCCCATGGGACCTGATGGGCTGAAGGGGGACAGGGGAGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCA
GGAAGGGCTGATGGGTGAGGACGGGCCCCCCGGCCCCCCTGGCGTCACTGGTGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGA
GAAGGGCCGCACTGGAGCCAAGGGTGCCAAGGGCTATCAAGGACAGCTGGGTGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCAC
TCCAGGCCCTAAAGGGTCCCGGGGCAGCCTGGGACCAACGGGTGCTCCGGGACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTA
TGATGGACACAAAGGCATTGTGGGACCCCTTGGACCTCCTGGACCAAAAGGCGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGG
GCCCCCTGGGCCACCTGGAGATCGGGGCCCTGTGGGTGATCGAGGAGACCGCGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGG
TGTGCAAGGCCTCCGTGGAAAGCCAGGCCAGCAGGGCCAACCCGGGCATCCGGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGG
CGCAGAGGGACCAAAGGGAAAGCAAGGCAAGGCAGGGGCCCCAGGCCGGAGGGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGG
CGTGGTGGGGAGACAGGGCCTCGAGGGCATCGCTGGACCAGATGGGCTTCCTGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGG
AGACGATGGGGACCCTGGCCCCATGGGCCCTGCTGGGAAGAGAGGAAATCCAGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGG
ATTCAAGGGTGAGAGTGGGTTACCCGGACAGCTGGGTCCCCCTGGCAAGCGAGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGG
GGAGCCTGGGTCCAAAGGCCAGCCGGCTGACGGAGCCAGTGCAGCCGGAAGGAAAAGCACTGCGAGCAGGGAGCGCTTGAAGCGCAGCCA
GAAGAGCACCAAGGTGGAGGGCCCAGAGCCAGTGCCAGCCGAGGCCTCGCTGAGTGCCGAGCAAGGAACGATGACGGAGGTGAAGGTGAA
GACAGAGCTGCCCGATGACTACATCCAGGAGGTGATCTGGCAGGGCGAGGCCAAGGAGGAGAAGAAGGCGGTCAGCAAGGATGGGACCAG
CGACGTGCCTGCCGAGATCTGCGTGGTGATCGGCGGCGTCCGCAACCAGCAGACCCTTGGGTCTTACGAATGCGGAATCTGTGGCAAGAA
GTACAAGTATTACAACTGCTTCCAGACCCACGTGCGGGCGCACCGAGACACCGAAGCCACCTCAGGGGAGGGAGCCTCCCAAAGCAACAA
TTTCAGGTACACATGTGATATCTGCGGGAAGAAGTACAAATACTACAGCTGTTTCCAAGAGCACCGAGACCTGCACGCAGTGGATGTGTT
TAGTGTGGAAGGGGCCCCTGAGAACCGGGCAGACCCCTTCGACCAAGGTGTCGTGGCCACGGACGAGGTGAAGGAGGAGCCCCCGGAGCC
ATTCCAGAAAATCGGGCCAATGAACAATATTACATCAGACATTTTTAAGAAGAAAGAAGTTAGGCAGTGCCAAAAGAGAGAAACTGGCAA
TTACACCTGTGAATTCTGCGGCAAACAGTACAAGTACTACACTCCCTACCAGGAGCATGTGGCCTTACACGCCCCCATCAAAAGCGCTTT
CAGTCGGAGAGTAGAAGGCAAAGCACAAAACCACTTTGAAGAGACGAACAGCAGTTCGCAGAACTCCAGCGAACCCTACACCTGCGGCGC
CTGTGGGATCCAGTTCCAGTTCTACAACAACCTGTTGGAGCACATGCAGTCCCATGCAGCTGACAATGAAAACAACATTGCCTCCAACCA
GTCCCGATCGCCACCTGCTGTTGTAGAAGAGAAGTGGAAACCTCAGGCCCAGAGGAACAGTGCCAATAACACCACTACCAGTGGTTTAAC
ACCCAACAGCATGATCCCCGAAAAGGAGCGGCAGAACATCGCAGAGCGGCTGTTGAGGGTCATGTGTGCCGACCTGGGTGCACTGAGCGT
GGTCAGCGGGAAGGAGTTCCTGAAGTTGGCCCAGACCTTAGTAGACAGTGGTGCCCGCTATGGGGCCTTCTCGGTCACTGAAATCCTGGG
CAACTTCAACACGCTGGCGCTGAAGCACCTGCCACGCATGTACAACCAGGTGAAGGTGAAAGTGACCTGTGCCTTGGGCAGCAATGCCTG
CCTAGGCATCGGTGTCACCTGCCACTCCCAGAGTGTTGGCCCTGACTCCTGCTACATCCTCACAGCCTACCAGGCCGAGGGCAACCACAT
CAAGAGCTATGTGCTTGGTGTGAAGGGTGCGGACATTCGCGACAGCGGTGACCTTGTGCACCACTGGGTGCAGAACGTGCTGTCGGAGTT
CGTGATGTCGGAGATCAGGACAGTGTACGTGACGGATTGCCGGGTGAGCACGTCCGCCTTCTCCAAGGCCGGCATGTGCCTTCGCTGCTC
AGCCTGTGCCTTGAACTCGGTGGTGCAGAGCGTGCTGAGCAAGCGGACACTGCAGGCCCGCAGCATGCACGAGGTCATCGAGCTGCTCAA
CGTGTGCGAGGACCTGGCGGGCTCCACGGGCCTGGCCAAGGAGACCTTCGGGTCGCTGGAGGAGACGTCTCCACCACCCTGCTGGAACTC
GGTGACGGACTCACTGTTGCTGGTGCATGAGCGCTATGAGCAGATCTGCGAGTTCTACAGCCGGGCCAAGAAGATGAACCTCATCCAGAG
CCTCAACAAGCACCTGCTCAGCAACCTGGCGGCCATCCTGACGCCGGTGAAGCAGGCAGTCATCGAGCTGAGCAACGAGAGCCAGCCCAC
CCTGCAGCTGGTGCTGCCCACCTACGTCAGGCTGGAGAAGCTGTTCACGGCCAAGGCCAACGACGCAGGCACTGTCAGCAAGCTCTGCCA
CCTCTTCCTGGAGGCGCTCAAGGAGAACTTCAAGGTGCACCCGGCCCACAAGGTGGCCATGATCCTGGACCCGCAGCAGAAGCTGCGGCC
TGTGCCACCCTACCAGCACGAGGAGATCATCGGCAAGGTCTGTGAGCTCATCAACGAGGTGAAGGAGTCCTGGGCCGAGGAGGCCGACTT
CGAGCCCGCTGCCAAGAAGCCCCGCTCTGCTGCCGTCGAGAACCCCGCAGCTCAGGAAGATGATCGGCTAGGCAAAAATGAAGTGTACGA
TTACCTGCAGGAGCCCCTCTTCCAGGCTACCCCTGATCTCTTCCAGTACTGGTCGTGCGTTACCCAAAAGCACACAAAACTCGCCAAGCT
CGCCTTCTGGCTCCTGGCGGTTCCGGCCGTGGGCGCCAGAAGCGGGTGTGTAAATATGTGTGAACAAGCGCTTCTAATCAAACGGAGGCG
GCTGCTCAGTCCAGAAGATATGAATAAACTCATGTTTCTGAAATCCAACATGCTTTAAGACTTGACTTCGGGGGAAAAAAAAAGAAAAAG
AGAAGATAACATTAGAAAAAAACCACACAACACTGTCACAAAGAAAAGGAATTTAAGTTCTAAACACTGTGGACCTCATTATAAATGCCC
CCTGGAAACTTAAGTGCTTTTTTTATATGTGTGTGTGTGCGTGTATGTACACAGCCACACGTGTGTGCACGTGTCTGAACACGTGCTGTG
GTTGTGGGGGTGTGGGGGGGTCTCTGTGCTCATCTCCATGGCCAGAGAAACTTTGCACACACGCACACACACACACACACACACACACAC
ACACACGACCCTGGTGCGTGTACATACGCCTGTGCTTGGACGGGTGTGCATTGAACTGGGCGTGTCAGGAAAGCTGAGCGATTGGGAAAG
AGGGAGATGTTTCACCTCCTTTTCTCAGTAAGGGGGCTTTAGAAGACTCCGCTTTCAGGTGTGCAGATTGGCAGAAAGCTGATGTTGTGA
AATGTTCAGGCAGCTGAGATCTGAAGTGACTTGACGCTCTCTGTCCTTCACCCCGGTCCTCCTTTTCCCTCTTTGACCCTCTTCCAGCCC
TCCTACCCTCCTGATCCCATTGTGCACCCCCCCACACACTCGGCTGCTCTGCTGTGGACTCTCCACACTGCATCAGATGGACGGTTTCTG
CACTGGACTTTGTTTCTTGTTCACCTTCAGGGCATTGAGCTGCTGCCTTTGAGATACCCCTTGGGTGTCCCGGGGCAGCCGCCTTAGAAA
CACACCTATCTATCTCCCCAAATCAGGAAAGGAGACTTAAAGAGTATAAAGCTGACATTTTGCTTTTTAATATAAGAGAGGAGAAAAAGA
CATTTTTCAGAGAAGTATAGATACTGTCTCCACTCCCTAATAATTTCTCTCCCTAACATTTTAGCAATTTTTACCTTGTTTGGGGGTTCA
TTTTGTTTCTTCAGATTTGATTTAGACTCTGCTAGGAGGCACTGAATGTCTATAACTTATGTTTTGGAGTTTTGTTTTTTTACTTGCCCC
TTTTGTTCCTCAAGTCACACTGTAAACTAGCTCATCTCTGTGGTGTACTCAGTATCCTACAGTCTTTCTTGGCCTTCCCTGTACAGTTCA
GTTTTCACATATTCGAACGGCCAAGACCAGGTTCTTGGCTGTGCTATTTGGAGACCAGGCGTTGGGGAGGATTCACGGGTTCCACAGCTG
CGGGGTTTGGTGGCCGTAGGGGAAGCAGTGGTTTGGGAGTTCTGAATGTAAGCGCCAGAGCTGCCCTCCTGGTCCGCTGTGCGTGGTACC
CAGTGTGCATCACACTACTCACCCCCTCCCGGACCCTGGCAGTCCACAGCGACTCCGAAGTCAGCCCATAGTCACATCCACCACACCTCA
GACCTGCCACAGCCTCTCCTCACTTCCCAGGACCCTGAGGCTTCCAGGAGCTCTGCTGCCCACAGCCCTCGGGGTCCTCACTCACACCTC
CGACTTCCAGGACGGCAGTGAGCATGGTGCCTTGTGGCCCCAACAGTTGATGTTCCGAGGGTGGGATGGTGTTTGGCCATGTTCGACTCG
ATGCTGTGAAAGATGTCTTCAGGCTTTTCTCTCCTGTTCCCCCAGCTGTGAGCAAATTAGGTTCTACACACACAGTTCGGATGCCAAGGG
TGACACCCCATTCCCTTCACAAGAGGCGGTTCTGTCACAAATCAGCACTCCACCCCCACCACACCTCTCAGTGAATGAAGTGCTGGTGGT
CTCACTCCCCTGGTGACCCTTAGCCGTGGGATGGGGTGGTTACACTAAGGCTTCAAGCTGAGAATGGCCATCATGGCGGGAGGCTGTTTG
CAAAGGCACCTTCTGTCATCCTGGGGTTGGCTAAGTCAACTCCACCCCTTCCCAATAATAAAGCATCACTCAACTGTGAGATACCTCGAC
TACAAAAAGCACTGTACCACAGCCCTCTCCCCCTGGGTCCATGACAGGAGCAGGGAGTAAAGTTGATTGCAAACCTCATGAAGGCTTAGG
ATCATGGACCTGGAACATAGTGTTTGGGGGCCAAGCCTGCACACTTTGCCTCATGAGAACTCACCCAGCTCTCCCCTTGAAACTTGGACA
CACTGAAATGGATCAAAGTGGGCCATTTCCACATTTGCTCCAGCAAACTGTGGTCTCAGGAACTACCATGCCATTTCCTCTCCTGGAGAA
GTTCTAGGTATTACCTCCACAACATTTCCAACTGGGGGACTGAGCCCACTTATCAGAGAAGAGCCGCCATCCACACTGGAGCAGGAACAG
GGAGAAATCCAGACAGGAACCTCATGTCACTTCCTAGGGAATATGGGAAGAAACATCAGCAGACTTTATGATGTCAGTTGGGCCTTTGGA
GGCATTCTGGAAGGTGGCCTCAGCATCACTGATGATTGACAGATGCTACAGCAAAAGGTCCCTCTAGCGTTGCTTGACTGCTGGGGAAGG
GACAGTGACCGGCACTTTGACCCACACAAGGATAGGAGCTGCCTACTTTGTGTGGTAGGTGAGAGCAGAGCCTGGGAGCCCATCCTCCCT
CTACTTGGAGCAAAGTTGTGCTGGTGATGCCCCATTATTGGGCCAGTTGATTAGAAAATAGGCATTTCACTTTCTTGGAAAGCCATCGGA
CTAAGCCCAGATGTGCATTTAGAGCACTCAGCATTCTTCTCTTTGAAGCATGGGATGTCTGTCCTCCAGGAAGAGATTTGATCTTAGGTT
GTTACCTCCCTTTCACTTCTTTTCCACCTCAATTCAATACTTAGGGGTTGGCTTGCCTCTGCAGGTTTGATGTGAATGCCACTGGGTACT
CAGAAAGCTGTCCTCTGGGGCTGCCTTGTCCAGTTAGATAACAAGATAGCAGATGATTGTTTCTTGCAACCTCTGGTTCCCTCCGGAAAC
TGGTGTCACCAACAGGAAAGGCTGTACCAAGGTGCCCTCTTCTCAGACAGGCTGTTCTCAGAGTGCAAATCCTGCTGCAACTAACAGCTT
AATAAAACCCAAAGATCTCACAGGTCCAGCCACTGGCCCCTTTATCTCCAACAATATCCACCTCACCAAATTCTAGTTCAGCCAAAGGAT
TGAGACAGGCTCTTCCAGTTCATCTCCTGGTGTCCAGCCTGACCTTCACATCTGGAAGGATTTTGTCGTCTGCCTCCCAGTTCTGGGTCC
ACTGTAGGTCTTTCCATCACAAGCCTTTGGGGGATCTGGGACCAGGAATTTGGGCCGTTTCTACCATATTCTCAGCAGCCTAAGGTGGTG
GCCTGCTGATGTGGAGACTACTCACCTTGAGCCATGTGGTCCCCAGGACAGAAATGGCCTTTGTTTTGACATACATGGACCCAAAAGGGG
AGGTGAAGAAAACACACCTCCACCTGGCAAGTTTTTCTCCCTCATCTGAGGTCAGTTGCTTCACCAACAAAGCCCAAGCCAAGAACTGCA
GCGTTGAGGGTTGTCCCTCGGAGTGGAGTAGCCCAAGGAATCTCAGGTCCACCAAGAGCATTGGTACCATCTGGGCCACGGGTGGATGCC
TTTGTTCTGGCACAGTTCTCCACTTCCCGATTCCTGGCTCAGCCAGCCAGGCCTCCCTCTAATGGCATTTAGTAACCAGGAAACAAAACA
CATGCCACCTGAGCAAAACTGCCTGCACTTCATCTCTGGAGGTTCGCTGCACAGAGGCCACCTGCCGCATCACCAGTGAGGAAGCTTTGC
CACCATCCTGCTTGGCAGCTTCACACTTGACATCTGAGGATTGGTTTTTGGCTGGAAAAAGGGTACCAGGGTTTCCTGGCAAGGACAGGA
GAGCAGTGCAGTGACACAGATGAGAAGCTGTGAGTCTCCAGGATTCAAGGAAGCCACCAGGTGTGCAGGCTGGGAAGAGACATCTCTTTC
AGTTTGACCCTTTATCTCCTGCACTTTTAAAGAAACACCAGAGAAAAAATCTACAAGGCGTGTTTCCACTGAAGCTGAACCTCTGCCTTT
AGGAGTCCCCTATATTTGAGCAAGGCCACCTGCTTCCCCTGGACTTGAGCTGGACTCCTTGAAGAGTGGGCTTCTGGAGAGATGTTAGGA
ATATAGCACATGCTCTCTGGGGGCCACAGGGTCATTGGGAAGGTTTGAAATGAAGATGGGATGTGGCTGGAACAGCCTGTGAGATGGCTC
CATTGGGGACACTCCCCTCATCTTGTCATCACGATGGATATGCTGGAAGAGGAGGTGTCCCAGTGAGCCGCCCGAAGTTCATAGCTTTGC
CCTCGCCTTGGCAACAGCGGCAATGCCTCTATCTCTGGGATGCATCTTAAGGAGGGCTCCTAACAAGGCCGATGATTTAGACAGAACAAG
AGACTAAGTAAGGTCCGGCTATCCCGTGGAGCCAGTAGTAGGTGGGAGCTCCTGTCCCCGCCAGCCCTGCTCCAGCCCCCGTGTCCAGCT
GGGCCAGTGGAAGAACTGGGAAGGAGGAAGCCCCTCCCTTTCACTGTGGCTAATGTTTGCTAGGCCAGTTATGGTGAACCAATGATACAG
TGTTTTCCCTCTTAACGTTCCCCTCCTGGTTTTGCCTTTTCAGGGTTTTCTGGGGGATTTTGTTGTAGTAGTTGCTTTTCTTCCTCTCTC
ATTTGGGTTTGAGGATTGTGGTCGGGGGAGCCCTGGCTTTCACCAAAGGAGCCCAGTGGTTTCTGTGGAAGAGGCGCCCACTCCCACTTT
AATGAGGGTGAAGATTGTCAGGTCACTGTTTGACATATTCATGCCCCGTCCCTTCCCCCCCCACCCCCCCGCCCACCCACCACGGGTGTC
GCTTTAAAGAGTCAATTCTTGTACAGAGAAGGATTTGCTAGGTTTGCATTTGGGTGTTAGCATCACGACCCACGAGGGCCCTGCCCAACC
GTGCGTCCCATGGGGCACCTTGACTCTTCAAACCAAAATTCCTTAAAGGGGCACAGCCCAGCCTTGTCCGCAACCTCAGGGGCCTGGGAT
TCCTGTGGCGCTTCCTGAATTCCAGGTTGGCACAGATGATGAGGTCTGAGACCAGCCGGAAGGAGGGGCTCCTGCCATAACCCAGGTGCC
AGCCGGTCTCCGCCTAGGACCTTCCCTCCCGCCCAGCCAGGGTGGGCGGCATCCTACGCGGTGAAACGAGCTCATGGACTGACCCGGGGC
TGGGCCTCGCCAGCCAGGAGAGAGCGAGGGCCGCACGGCAGGGCTGGCCCAGGCAGCTCGTCCAGGGCCATTCAGATCCCAAGCATCAGG
AAATCATTTTGTACAACCACCCGAAGCAGAGATATTTTTTAAGAAGCGTAAATTATTTTCAGTTGTTTTCTGATCCTGCCTTTTTCTTTT
CCCCACAACTTCACGCCAGTGAGTCGTTCACATCAGGTAAATCTTGAGAAAGCCTTGGTGCCCTCCTCCCCACCCCCCACTCAGTAACCA
CGTGCGTGCACCCCCGCATCCTTTCTCAGTAGTTAAGACGTTCTAGGCAATACCATAGACACATCTGACTGTGTCTCTCTCTTTGAGTGC
AAGAAACTCAAGTCATCTTAAAAAAAAAAAAATACAAAAAAAATTTACAAAAAAACAAACACAAAAAAAATATCTTTTTTAGGCCAGAGT
TTTCTACAGGTATTAATGAATATTTTTCTTAATCCTTATAAGTTTTATGTGTTTAATATTTCTTAATACCGGTAGCATTAATTTATACTT
TTGTAGCAACACAATATTTTTATAAACAGCCGGTGCTTGGCTCAAGTCTTCACGAGGGGTTTAGGCAGGGCCATCTTGGGGACCCTGTGT
ACCATGTACTGTATTTAAAAAAAAAAAAAGTTACCTATTGTCACACTTGCTGTGTTAATTAACAAAAGATGTTGTGTGCGGTCTCCTGTA
TCGGTGTGGATCCAACAGCTCTCCAGGGAGTCACATTGCATGGGGGTTGAGTTGACGGTTCTTGTGATATGTAAACCCCCGAGACCAAAC
TTGAGGGTTTATTTAGGGTTTTCTGTTTGTCCTTTGGGTTTTTGTTTCACTTTGTTTTGGTGCCGTTTCTCCATTTACAGCCAAATCAGT
TTCATGATGTTCAAAACATTTACTGATGTCAAATGGAGGAAAGGAACAGAAAAAAAGATTTTTACAAAGTAATAAAATTTAAAACTGAGC
TGTTTAATGTTGCTGTTTTTACCTGTCTGTTCTTGTCCAAAAGTGGAACATTCCCAGGGAGAAGAGGAAGGTTCCACTCGGTTCTTTAAG
TCGCCAAAAGCCCCAGCCCGGGATTCAGTACCTCCCCTGCCCCCCGAATTCTTGCAGCACTATTTCCCAGTTGGTTGATGCCAAGGCAAA
AAGATAACTTTTAACAGTTAGAGAGGATCAGTTGCTTAAATGATTTCATGTCAGTGTTGTATTTATGGTTTTACAATAAAACAACCTTTA

>18271_18271_3_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731397_ENST00000288466_length(amino acids)=2378AA_BP=635
MGAGSARGARGTAAAAAARGGGFLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVI
PAALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVP
VLLPFHRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLE
NLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKIT
ATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSS
KKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSE
ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPK
GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP
GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL
GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI
GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPV
GEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSR
GLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDL
GPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAK
GYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP
VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI
AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPAD
GASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVI
GGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEATSGEGASQSNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVEGAPENRA
DPFDQGVVATDEVKEEPPEPFQKIGPMNNITSDIFKKKEVRQCQKRETGNYTCEFCGKQYKYYTPYQEHVALHAPIKSAFSRRVEGKAQN
HFEETNSSSQNSSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNTTTSGLTPNSMIPEKER
QNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQ
SVGPDSCYILTAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFSKAGMCLRCSACALNSVVQS
VLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLSNLA
AILTPVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKVHPAHKVAMILDPQQKLRPVPPYQHEEII
GKVCELINEVKESWAEEADFEPAAKKPRSAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAV

--------------------------------------------------------------
>18271_18271_4_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731397_ENST00000374126_length(transcript)=7861nt_BP=4975nt
CGGCGGGGAGGCAGCTTCCACCGCCCTCCGCGCGCCCTCACCCGGCCTTGCTCTGCCTCCGGGGACCGCCAGCAGCCCGCCTCCAAAAGT
TTGATCATCTCTCTCTCTCTTTTTCTTGCTTCTTCTTCCTTTTTGGTGGAAGCAGAAAAGGACCGAGGCAGGGGCGAGCGCGGCGCCCGG
ACTCCTGGGACCATGGGCCTGGCGCGGGCGCCCGCGGGGCCCCAGCCGCGCTGCCTGCCTGCTCGGGCGCCCCTGGGCGCGGGGCTGCGC
TGGGGGCGCGGGGGCCGCGCGCTCTAAGCCGGCCTGGCGCGGCGGGGCGGGGGGCTGGCGGCCCCATGGGGCGCGCCCACACTTGCCCCC
CGGGCTCGGGAGCATGAAGTAGGGGCCTGCCATGGGAGCGGGATCGGCGCGGGGGGCCCGAGGCACAGCGGCGGCGGCGGCGGCGCGCGG
GGGGGGGTTTCTCTTCTCCTGGATCTTAGTCTCGTTTGCCTGTCACCTGGCCTCCACCCAAGGAGCTCCTGAAGATGTGGACATCCTCCA
GCGGCTGGGCCTCAGCTGGACGAAGGCCGGGAGCCCTGCACCCCCGGGAGTCATTCCTTTCCAGTCGGGCTTCATCTTTACGCAGCGGGC
CCGGCTCCAGGCTCCCACGGGCACCGTCATTCCTGCCGCCTTGGGCACAGAGCTGGCACTGGTGCTGAGCCTCTGCTCCCACCGGGTGAA
CCATGCCTTCCTCTTCGCTGTCCGCAGCCAGAAACGCAAGCTGCAGCTGGGCCTGCAGTTCCTCCCCGGCAAGACGGTCGTCCACCTCGG
GTCCCGGCGCTCAGTGGCCTTCGACCTCGACATGCACGACGGGCGCTGGCACCACCTGGCCCTCGAGCTCCGAGGCCGCACAGTCACTCT
GGTGACTGCCTGCGGGCAGCGCCGGGTGCCTGTCCTGCTGCCTTTCCACAGGGACCCTGCACTCGACCCTGGGGGCTCCTTCCTCTTTGG
GAAGATGAACCCGCATGCAGTCCAGTTTGAAGGTGCTCTCTGCCAGTTCAGTATCTACCCTGTGACGCAGGTCGCTCACAATTACTGTAC
CCACCTGAGGAAGCAGTGTGGACAGGCTGACACGTACCAGTCCCCACTGGGACCTCTCTTCTCCCAAGACTCTGGCAGACCTTTTACCTT
CCAGTCCGACCTCGCCCTGCTAGGCCTGGAGAACTTGACCACTGCCACACCAGCCCTGGGGTCACTGCCAGCAGGCAGGGGACCCAGGGG
GACTGTGGCACCCGCCACGCCCACCAAGCCCCAAAGGACTAGCCCCACAAACCCTCACCAGCATATGGCGGTGGGAGGCCCAGCCCAAAC
CCCGCTGCTACCTGCCAAGCTGTCAGCCAGTAACGCACTTGATCCCATGCTCCCAGCCTCTGTTGGCGGCTCTACCAGAACGCCTCGCCC
TGCGGCCGCTCAACCATCACAGAAGATCACAGCCACCAAAATCCCCAAAAGCCTCCCTACCAAGCCTTCGGCCCCTTCTACTTCAATTGT
GCCCATCAAAAGCCCCCATCCTACCCAGAAAACAGCTCCATCTTCATTTACAAAGTCAGCCCTACCCACTCAGAAGCAAGTGCCACCTAC
TTCCCGTCCAGTTCCTGCCAGAGTCTCCCGTCCCGCAGAGAAGCCCATCCAGAGGAACCCGGGAATGCCCAGGCCCCCACCGCCCAGCAC
CCGGCCCCTACCTCCTACCACCAGCTCCTCTAAAAAACCCATTCCCACACTAGCTCGGACTGAGGCCAAGATAACCAGCCATGCCAGTAA
GCCGGCCTCTGCCCGCACCAGCACCCACAAACCTCCCCCATTTACTGCTTTATCCTCATCTCCTGCCCCTACTCCTGGTTCTACCAGGAG
TACTCGGCCACCAGCCACGATGGTACCTCCAACTTCGGGCACCAGCACTCCCAGAACAGCACCTGCCGTCCCCACTCCTGGCTCAGCTCC
CACTGGAAGCAAGAAGCCCATTGGATCGGAAGCCTCAAAGAAAGCCGGACCCAAGAGCAGCCCCCGGAAGCCTGTCCCCCTCAGACCTGG
GAAGGCAGCCAGGGATGTCCCCTTGAGCGATCTGACAACCAGGCCTAGCCCCAGACAGCCCCAGCCCAGTCAGCAGACCACCCCGGCCCT
GGTATTGGCCCCGGCGCAATTCCTGTCCTCCAGCCCCCGGCCCACGAGCAGTGGCTATTCGATCTTCCACCTGGCAGGATCTACGCCTTT
CCCTCTGCTGATGGGGCCTCCGGGACCCAAGGGAGACTGTGGCTTGCCGGGTCCCCCTGGGCTACCTGGGCTACCTGGAATCCCTGGTGC
ACGTGGGCCTCGGGGTCCTCCTGGGCCTTATGGAAATCCAGGTCTCCCCGGCCCTCCTGGAGCCAAAGGACAGAAAGGGGACCCAGGGCT
CTCACCAGGAAAGGCCCACGATGGGGCAAAGGGTGACATGGGCTTGCCTGGGCTCTCCGGGAATCCAGGACCTCCGGGACGAAAGGGACA
CAAGGGCTATCCTGGACCGGCAGGGCACCCCGGAGAACAGGGGCAGCCAGGACCTGAGGGCAGCCCAGGGGCCAAAGGTTACCCTGGCAG
GCAGGGGTTACCTGGACCGGTAGGAGATCCCGGCCCCAAAGGCAGCAGGGGCTACATTGGGCTCCCAGGGCTCTTCGGCCTGCCAGGGTC
TGATGGAGAACGAGGCCTGCCTGGCGTTCCTGGCAAGAGGGGCAAGATGGGTATGCCGGGGTTTCCTGGAGTCTTTGGGGAAAGAGGCCC
TCCTGGACTGGATGGAAATCCTGGAGAACTGGGCCTGCCAGGCCCCCCTGGAGTCCCCGGCCTCATTGGTGACTTAGGAGTGTTGGGTCC
GATTGGCTACCCGGGACCCAAGGGCATGAAGGGACTGATGGGCAGCGTGGGGGAGCCCGGACTGAAAGGTGATAAGGGTGAACAAGGGGT
TCCAGGTGTGTCAGGAGATCCCGGATTCCAAGGAGACAAGGGGAGCCAGGGGTTGCCAGGGTTCCCCGGTGCACGGGGGAAGCCAGGGCC
TCTGGGCAAAGTCGGAGACAAAGGATCCATTGGGTTTCCCGGGCCCCCTGGACCCGAGGGATTCCCAGGAGACATCGGCCCCCCTGGCGA
CAATGGCCCAGAAGGCATGAAGGGTAAGCCTGGAGCCCGAGGCCTGCCGGGACCCCGTGGGCAGCTGGGGCCCGAGGGAGATGAGGGACC
CATGGGGCCGCCAGGGGCCCCTGGCTTGGAGGGTCAGCCTGGCAGGAAGGGGTTTCCTGGGAGGCCCGGCCTGGATGGCGTGAAGGGGGA
ACCAGGGGATCCTGGTCGGCCGGGGCCTGTGGGAGAGCAGGGATTTATGGGATTCATTGGTCTGGTCGGGGAGCCAGGAATCGTGGGAGA
AAAGGGTGATCGTGGCATGATGGGACCCCCAGGCGTGCCTGGACCCAAGGGGTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGAC
CCCTGGAGAGCCTGGACCCCAGGGTCCTCCAGGATCTCGAGGCCCACCAGGCATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACC
GGACGGACCAGCTGGGGAGCAAGGGTCCAGGGGCCTGAAGGGCCCTCCAGGACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGT
GGCTGGTGAGCGAGGCCACTTGGGCTCGAGAGGCTTTCCTGGCATCCCGGGTCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGA
ACCGGGCCCTCAGGGACCCCAGGGGCCAATTGGGCCTCCAGGAGAGATGGGACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCT
TCCTGGGGAAGCCGGGATGAAGGGTGACCTTGGACCCCTGGGCACTCCTGGGGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCT
TGAGGGTGACAGTGGCCCCATGGGACCTGATGGGCTGAAGGGGGACAGGGGAGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCA
GGAAGGGCTGATGGGTGAGGACGGGCCCCCCGGCCCCCCTGGCGTCACTGGTGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGA
GAAGGGCCGCACTGGAGCCAAGGGTGCCAAGGGCTATCAAGGACAGCTGGGTGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCAC
TCCAGGCCCTAAAGGGTCCCGGGGCAGCCTGGGACCAACGGGTGCTCCGGGACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTA
TGATGGACACAAAGGCATTGTGGGACCCCTTGGACCTCCTGGACCAAAAGGCGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGG
GCCCCCTGGGCCACCTGGAGATCGGGGCCCTGTGGGTGATCGAGGAGACCGCGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGG
TGTGCAAGGCCTCCGTGGAAAGCCAGGCCAGCAGGGCCAACCCGGGCATCCGGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGG
CGCAGAGGGACCAAAGGGAAAGCAAGGCAAGGCAGGGGCCCCAGGCCGGAGGGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGG
CGTGGTGGGGAGACAGGGCCTCGAGGGCATCGCTGGACCAGATGGGCTTCCTGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGG
AGACGATGGGGACCCTGGCCCCATGGGCCCTGCTGGGAAGAGAGGAAATCCAGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGG
ATTCAAGGGTGAGAGTGGGTTACCCGGACAGCTGGGTCCCCCTGGCAAGCGAGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGG
GGAGCCTGGGTCCAAAGGCCAGCCGGCTGACGGAGCCAGTGCAGCCGGAAGGAAAAGCACTGCGAGCAGGGAGCGCTTGAAGCGCAGCCA
GAAGAGCACCAAGGTGGAGGGCCCAGAGCCAGTGCCAGCCGAGGCCTCGCTGAGTGCCGAGCAAGGAACGATGACGGAGGTGAAGGTGAA
GACAGAGCTGCCCGATGACTACATCCAGGAGGTGATCTGGCAGGGCGAGGCCAAGGAGGAGAAGAAGGCGGTCAGCAAGGATGGGACCAG
CGACGTGCCTGCCGAGATCTGCGTGGTGATCGGCGGCGTCCGCAACCAGCAGACCCTTGATGGAAAAGCGCCCGAAGGCAGCCCCCACGG
TGGATCTGTGCGAAGCCGGTATTCAGGGACCTGGATTTTTGACCAAGCATTGAGATATGCATCTGGGTCTTACGAATGCGGAATCTGTGG
CAAGAAGTACAAGTATTACAACTGCTTCCAGACCCACGTGCGGGCGCACCGAGACACCGAAGCCACCTCAGGGGAGGGAGCCTCCCAAAG
CAACAATTTCAGGTACACATGTGATATCTGCGGGAAGAAGTACAAATACTACAGCTGTTTCCAAGAGCACCGAGACCTGCACGCAGTGGA
TGTGTTTAGTGTGGAAGGGGCCCCTGAGAACCGGGCAGACCCCTTCGACCAAGGTGTCGTGGCCACGGACGAGGTGAAGGAGGAGCCCCC
GGAGCCATTCCAGAAAATCGGGCCAAAAACTGGCAATTACACCTGTGAATTCTGCGGCAAACAGTACAAGTACTACACTCCCTACCAGGA
GCATGTGGCCTTACACGCCCCCATCAGTACTGCCCCCGGGTGGGAGCCACCGGATGATCCAGACACGGGCTCTGAGTGTTCACATCCAGA
GGTCTCCCCATCTCCACGCTTCGTGGCAGCGAAGACCCAGACGAACCAGTCGGGGAAAAAAGCTCCGGCCTCCGTGGTCCGATGTGCCAC
CCTCTTACACCGCACCCCTCCAGCCACCCAAACCCAGACGTTCCGCACTCCAAATTCGGGATCTCCGGCGAGCAAGGCAACCGCAGCAGA
AAGCGCTTTCAGTCGGAGAGTAGAAGGCAAAGCACAAAACCACTTTGAAGAGACGAACAGCAGTTCGCAGAACTCCAGCGAACCCTACAC
CTGCGGCGCCTGTGGGATCCAGTTCCAGTTCTACAACAACCTGTTGGAGCACATGCAGTCCCATGCAGCTGACAATGAAAACAACATTGC
CTCCAACCAGTCCCGATCGCCACCTGCTGTTGTAGAAGAGAAGTGGAAACCTCAGGCCCAGAGGAACAGTGCCAATAACACCACTACCAG
TGGTTTAACACCCAACAGCATGATCCCCGAAAAGGAGCGGCAGAACATCGCAGAGCGGCTGTTGAGGGTCATGTGTGCCGACCTGGGTGC
ACTGAGCGTGGTCAGCGGGAAGGAGTTCCTGAAGTTGGCCCAGACCTTAGTAGACAGTGGTGCCCGCTATGGGGCCTTCTCGGTCACTGA
AATCCTGGGCAACTTCAACACGCTGGCGCTGAAGCACCTGCCACGCATGTACAACCAGGTGAAGGTGAAAGTGACCTGTGCCTTGGGCAG
CAATGCCTGCCTAGGCATCGGTGTCACCTGCCACTCCCAGAGTGTTGGCCCTGACTCCTGCTACATCCTCACAGCCTACCAGGCCGAGGG
CAACCACATCAAGAGCTATGTGCTTGGTGTGAAGGGTGCGGACATTCGCGACAGCGGTGACCTTGTGCACCACTGGGTGCAGAACGTGCT
GTCGGAGTTCGTGATGTCGGAGATCAGGACAGTGTACGTGACGGATTGCCGGGTGAGCACGTCCGCCTTCTCCAAGGCCGGCATGTGCCT
TCGCTGCTCAGCCTGTGCCTTGAACTCGGTGGTGCAGAGCGTGCTGAGCAAGCGGACACTGCAGGCCCGCAGCATGCACGAGGTCATCGA
GCTGCTCAACGTGTGCGAGGACCTGGCGGGCTCCACGGGCCTGGCCAAGGAGACCTTCGGGTCGCTGGAGGAGACGTCTCCACCACCCTG
CTGGAACTCGGTGACGGACTCACTGTTGCTGGTGCATGAGCGCTATGAGCAGATCTGCGAGTTCTACAGCCGGGCCAAGAAGATGAACCT
CATCCAGAGCCTCAACAAGCACCTGCTCAGCAACCTGGCGGCCATCCTGACGCCGGTGAAGCAGGCAGTCATCGAGCTGAGCAACGAGAG
CCAGCCCACCCTGCAGCTGGTGCTGCCCACCTACGTCAGGCTGGAGAAGCTGTTCACGGCCAAGGCCAACGACGCAGGCACTGTCAGCAA
GCTCTGCCACCTCTTCCTGGAGGCGCTCAAGGAGAACTTCAAGGTGCACCCGGCCCACAAGGTGGCCATGATCCTGGACCCGCAGCAGAA
GCTGCGGCCTGTGCCACCCTACCAGCACGAGGAGATCATCGGCAAGGTCTGTGAGCTCATCAACGAGGTGAAGGAGTCCTGGGCCGAGGA
GGCCGACTTCGAGCCCGCTGCCAAGAAGCCCCGCTCTGCTGCCGTCGAGAACCCCGCAGCTCAGGAAGATGATCGGCTAGGCAAAAATGA
AGTGTACGATTACCTGCAGGAGCCCCTCTTCCAGGCTACCCCTGATCTCTTCCAGTACTGGTCGTGCGTTACCCAAAAGCACACAAAACT
CGCCAAGCTCGCCTTCTGGCTCCTGGCGGTTCCGGCCGTGGGCGCCAGAAGCGGGTGTGTAAATATGTGTGAACAAGCGCTTCTAATCAA
ACGGAGGCGGCTGCTCAGTCCAGAAGATATGAATAAACTCATGTTTCTGAAATCCAACATGCTTTAAGACTTGACTTCGGGGGAAAAAAA

>18271_18271_4_COL27A1-ZNF618_COL27A1_chr9_117054490_ENST00000356083_ZNF618_chr9_116731397_ENST00000374126_length(amino acids)=2471AA_BP=635
MGAGSARGARGTAAAAAARGGGFLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQSGFIFTQRARLQAPTGTVI
PAALGTELALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVP
VLLPFHRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLFSQDSGRPFTFQSDLALLGLE
NLTTATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKIT
ATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSS
KKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSE
ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPK
GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP
GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL
GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI
GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPV
GEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSR
GLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDL
GPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAK
GYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGP
VGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI
AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPAD
GASAAGRKSTASRERLKRSQKSTKVEGPEPVPAEASLSAEQGTMTEVKVKTELPDDYIQEVIWQGEAKEEKKAVSKDGTSDVPAEICVVI
GGVRNQQTLDGKAPEGSPHGGSVRSRYSGTWIFDQALRYASGSYECGICGKKYKYYNCFQTHVRAHRDTEATSGEGASQSNNFRYTCDIC
GKKYKYYSCFQEHRDLHAVDVFSVEGAPENRADPFDQGVVATDEVKEEPPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIST
APGWEPPDDPDTGSECSHPEVSPSPRFVAAKTQTNQSGKKAPASVVRCATLLHRTPPATQTQTFRTPNSGSPASKATAAESAFSRRVEGK
AQNHFEETNSSSQNSSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASNQSRSPPAVVEEKWKPQAQRNSANNTTTSGLTPNSMIPE
KERQNIAERLLRVMCADLGALSVVSGKEFLKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTC
HSQSVGPDSCYILTAYQAEGNHIKSYVLGVKGADIRDSGDLVHHWVQNVLSEFVMSEIRTVYVTDCRVSTSAFSKAGMCLRCSACALNSV
VQSVLSKRTLQARSMHEVIELLNVCEDLAGSTGLAKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQSLNKHLLS
NLAAILTPVKQAVIELSNESQPTLQLVLPTYVRLEKLFTAKANDAGTVSKLCHLFLEALKENFKVHPAHKVAMILDPQQKLRPVPPYQHE
EIIGKVCELINEVKESWAEEADFEPAAKKPRSAAVENPAAQEDDRLGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAV

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Fusion Gene PPI Analysis for COL27A1-ZNF618


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for COL27A1-ZNF618


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for COL27A1-ZNF618


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource