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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:COPZ1-ONECUT2 (FusionGDB2 ID:18676)

Fusion Gene Summary for COPZ1-ONECUT2

check button Fusion gene summary
Fusion gene informationFusion gene name: COPZ1-ONECUT2
Fusion gene ID: 18676
HgeneTgene
Gene symbol

COPZ1

ONECUT2

Gene ID

22818

9480

Gene nameCOPI coat complex subunit zeta 1one cut homeobox 2
SynonymsCGI-120|COPZ|HSPC181|zeta-COP|zeta1-COPOC-2|OC2
Cytomap

12q13.13

18q21.31

Type of geneprotein-codingprotein-coding
Descriptioncoatomer subunit zeta-1coatomer protein complex subunit zeta 1coatomer protein complex, subunit zetazeta-1 COPzeta-1-coat proteinone cut domain family member 2HNF-6-betaONECUT-2 homeodomain transcription factorhepatocyte nuclear factor 6-betaonecut 2transcription factor ONECUT-2
Modification date2020031320200313
UniProtAcc

P61923

.
Ensembl transtripts involved in fusion geneENST00000416254, ENST00000549043, 
ENST00000262061, ENST00000455864, 
ENST00000549116, ENST00000551779, 
ENST00000552218, ENST00000552362, 
ENST00000553231, ENST00000548281, 
ENST00000548753, 		ENST00000491143, 
Fusion gene scores* DoF score12 X 4 X 10=4801 X 1 X 1=1
# samples 131
** MAII scorelog2(13/480*10)=-1.88452278258006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: COPZ1 [Title/Abstract] AND ONECUT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCOPZ1(54718965)-ONECUT2(55143669), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCOPZ1

GO:0006891

intra-Golgi vesicle-mediated transport

11056392

TgeneONECUT2

GO:0045944

positive regulation of transcription by RNA polymerase II

11478782


check buttonFusion gene breakpoints across COPZ1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ONECUT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-CW-5581-01ACOPZ1chr12

54718965

+ONECUT2chr18

55143669

+


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Fusion Gene ORF analysis for COPZ1-ONECUT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000416254ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
5UTR-3CDSENST00000549043ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000262061ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000455864ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000549116ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000551779ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000552218ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000552362ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
In-frameENST00000553231ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
intron-3CDSENST00000548281ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+
intron-3CDSENST00000548753ENST00000491143COPZ1chr12

54718965

+ONECUT2chr18

55143669

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262061COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14916551305413497147
ENST00000552218COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14912511305013493147
ENST00000553231COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14904431304213485147
ENST00000552362COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14904431304213485147
ENST00000455864COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14904431304213485147
ENST00000549116COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14899381303713480147
ENST00000551779COPZ1chr1254718965+ENST00000491143ONECUT2chr1855143669+14892311303013473147

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262061ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.77487930.22512077
ENST00000552218ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.77519410.22480585
ENST00000553231ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.775685370.22431463
ENST00000552362ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.775685370.22431463
ENST00000455864ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.775685370.22431463
ENST00000549116ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.77600450.22399549
ENST00000551779ENST00000491143COPZ1chr1254718965+ONECUT2chr1855143669+0.77593350.22406644

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Fusion Genomic Features for COPZ1-ONECUT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
COPZ1chr1254718965+ONECUT2chr1855143668+7.14E-121
COPZ1chr1254718965+ONECUT2chr1855143668+7.14E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for COPZ1-ONECUT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:54718965/chr18:55143669)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
COPZ1

P61923

.
FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity). {ECO:0000250|UniProtKB:P53600}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneONECUT2chr12:54718965chr18:55143669ENST0000049114302426_485409505.0DNA bindingHomeobox

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneONECUT2chr12:54718965chr18:55143669ENST0000049114302168_184409505.0Compositional biasNote=Poly-His
TgeneONECUT2chr12:54718965chr18:55143669ENST0000049114302317_322409505.0Compositional biasNote=Poly-Ser
TgeneONECUT2chr12:54718965chr18:55143669ENST000004911430237_56409505.0Compositional biasNote=Poly-Gly
TgeneONECUT2chr12:54718965chr18:55143669ENST000004911430281_85409505.0Compositional biasNote=Poly-Pro
TgeneONECUT2chr12:54718965chr18:55143669ENST000004911430294_101409505.0Compositional biasNote=Poly-Ala
TgeneONECUT2chr12:54718965chr18:55143669ENST0000049114302324_410409505.0DNA bindingCUT


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Fusion Gene Sequence for COPZ1-ONECUT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>18676_18676_1_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000262061_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14916nt_BP=55nt
TTTTGCGGCTCCACGTCGGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGAC
AGGAACAATTCCCAGAAGAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCG
TCAAAGGAGATGCAGATCACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGC
CTGGAGAAGTGGCAAGACGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTG
GGCACAAGTCACCTCCAAATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGT
GATTTGAAAGCACAATTCTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGG
AGTCCAAGTGCAAGCTGAAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTT
CCTGGAGCGAGTTAATTCCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTT
GCAGTCAGAGTTCCTATGAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAA
TCTAGCAACGAGAATGACCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAAT
GGTAATTACTGAGCACAAGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAAT
GATTTAGAAAGCTTTAAGTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAA
CCAGTCAGTTCACTTGCGCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCA
AGACACCTATTGTGAAGTCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATG
CAGACGCACACTCAGGAGGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTA
ATGTGTCCTTGGTTGATCAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTT
TTTCCTCATCCATCCCATTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTC
ATGACTGTCATCTAGTCCTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAA
GAAGCAGAATACTGCAAACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTC
TGCAACTCCGAATGGCATTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCA
GAGGGGTGGCTTTGCCACACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATG
TGCATATTTACCAGTGAATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTG
AGACTGACTTTTTTATGAATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAAT
GAATAAATAAATCCGTAAATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACA
CTGTGTTCAAACAGACCTCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAG
TGGCTGCTGCTTCATTTGACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACAC
GGAACAGAGCAACAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCT
GGCTAAAATACTAATAGCGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATT
TTATTGTTTCATTTCAATTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTG
GGATATTGAACAGTTCTCTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCT
TCTATGTTCAGAGTCTCATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAG
AACCAAAGAGTTTATAGAGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACAT
GTAAAAATAATTGCCAGTTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATA
TAAAATACATATATAGATCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATT
TGCTAAGTATTCGGTTCAGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTC
TATGGAAGTTTCTGGGACAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTT
TATTTGTATTCGGAGTCATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGG
GTCCTGACAGTGGGGTGCTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGA
AATCTGTTCTCCAGGAGCTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAA
GCCCAACTCCTGTTGCAATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTG
GCACTGGGGTGGGCAGTGGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCT
GGAGTCCTGCCCCTAGAGAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGA
GAATGTGACTCTCCACAATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATA
CTCCATGTTTCCTTTGTCAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTC
TAAAAGAGTCCTTGTGACATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTG
ATTCTTTGACATACTAATCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATT
ACAACATTGGTCAAACCAGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGG
AGCTTTAATAAATGTCTCATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATAT
ATGTGTATCTATACAGTTATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGA
AAGGTAATAGAATTTAACCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTT
ATAGTTTAGTATCCATTACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCA
GCCAAATTTCACATTCTTGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATA
GGCTTGCATTGTTTTTGTTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCC
AATACATTTCTTTTTTTAAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTT
TAGCTTGCACCATGCATAAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGC
TCCCTTTTCCCCCTGCAGGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTG
GAATGTAAATCTGATACACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTT
CTTTGTCTATACTGGGCACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAA
CTTCCCCACTTTTGAAAATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTG
AACTCGGATTTTCAGGAGTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACT
CTATTAAAAAGTGGAGAAAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATT
CGTAACAGGTTAGAGCTGACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAA
ATGGTAGATGAAGAAGGGGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTT
TAGCTAAGATCAAGTCACCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCC
CAGTTGGTTGTATAAGTCTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTT
CCAAGGTCGGGGAGGGAAAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATA
TAGGACCTCACATAGGTAGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTAT
TCTCACACACCAAAATGACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGA
AGTAACCAGCTAATACCTTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTT
AGCAGCAAGCATTTCATGTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAG
ATACATATTTTAACATGTGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTAC
AGACAAGCTTCATACGTATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTA
CATTGTTTTCATTATTTATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATT
AATTTCATTTGGGCATATCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATT
GATGACTTCGGTTGAATAGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAA
AAGAAAAAACAAAGAAAAAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACA
ATGGTACTGCGGTCTTGGGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGA
GAAAGTTTTAGAGGTTATAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACAC
CCTCTGCCCCACCCCACAGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTT
AAATTAGTTCCTAGTACATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTAT
CAAAACCTAGACCAATGGTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCT
GTTACAGACAGGGAAGAAATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACA
ATTTTTAAATTATTTAACTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATA
TTGTAACTTATTTATTTAACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCA
GTTTGTTTGCTGTCAGAACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGA
GACCCTGCTTCACCAGCCTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAAC
CCTTACACTAGCTGCTTCCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAA
AAAAAAATGAAAAACTTTCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGA
CACCAAAGATACCAAAGATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGT
ATGTACAGCCACAGCTCAGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTC
TTATATGTTTGCTGTCTGCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGG
AAGGAAACTGGTTGGAAATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAAC
CACAGAAGCTCTGACCATTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAG
TTATCCAAATCAAATAACTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCT
CTGCATGAGAGCGGTCCCACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCA
GCTGTAAAATTAGTCACAAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAA
TACTAGGGCTCATACGGGATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATT
GTATAGATAACTTTTTAATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTT
ATCAAGAAAGGGAACTTGACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCAT
TTCTAAGCCAACTCTGTATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCC
AAAATTACAGAGGAATATGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCT
TCAAGTTTCTTTAGATTCCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTC
AGCTTTTGACCAAATGGGTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACA
TAATGTAGTTATTTTGAGCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATC
AACAAAGCATAGCTAGTAGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCA
TCCTATGTGAAAGTTCCCTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGA
GTACATTGCTTTGGTTTTCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATT
GAGCAGCAGAGCTCCCTATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGG
CAGCCTGAACACAGAAAACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAAC
CACGGGACGAGTGCCTTGCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTC
AGCTTCAACTGGGCCTCCATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTAC
TAATACCAAAGGTTCTTTCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTA
TGAACCTGGGCATGTTGGCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATG
TTATTATAGCGTATGTAATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTT
TAGGTTGTGCTTTTGTAATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGAT
TGGGGAAAGTTGCAGAATGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATA
ATTATTTTCTACATTTGTGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTG
CTATAATTTTATGCATGAGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCC
CTTTGGTTCAATGGACTTTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATG
TACACAGTTCAGCCTCAGACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAA
AATGAGTCACATTGAATTGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGG
ATCCTCATAACCCAAATATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAA
AAGGAGTTATTTTGGCTTTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTG
ATCTCTGCTTGGGAATGGCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGC
ATCAATATTACTAACTCTTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAAT
ACGCAGCCATTTCCCAAAACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGC
CCAACAATGTTCCATCTACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAA
TTATCTGAGGCCTCTATATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCA
TTCTCCAGTTTCATATTTCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAG
CCTAGGGAACCTTGGTTGAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAG
GGTATATTGGGAACGTGCTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGA
TATATAGTCTTTTTATTTTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGA
TGATTGTAATAGTGTTTAATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACT
CACAAACCCACAAACTGTTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTA
TTTGAGACATGAGTGTACCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTAT
GAAACCCAAGGTATATTTTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGT
TTTCCAGACAACTGAAGTAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTT
CCTTGGAGACACATAACTACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAA
GGCAGGTCATGGGCTGGAAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTA
ACCTCACTCTCTCTGGACTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGA
AAGGCAAGAAAAAGAAAATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGC
TATTGCAGCCCATCTGGTGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCAT
CCAGTGGGGCTCTTCCACATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTA
TTTAGAAAACAAAGAAAGGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAAT
ACAAGAGGGAAAAGGAGACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATC
TGTCTTGGGCGACAGGCTGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTAT
TCAAAAAGTTGTAGAGTTTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTC
TAGGAAAGTTTTTTCAGATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCAT
TAACAGATACTTCCTTGAAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTAC
CGTGAAATGTTGTAAAACACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAG
TTTAGATGCAGGGACTGAGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAAT
CCAAGAGCAGTTCAGTCTTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATT
AGTTCTCTTCTTCATCTTTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCA
AATTTTTCCACCCAGACAATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCA
CCAAAGTGAGTGAAAACAAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTT
AGACCCTGGCCTCAGATGTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCT
ATACTGTTGACTGCTTGATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGT
TTAAAGTTTCAAAATTTAAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACC
GTACTCTGCCACCTGCCTTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATT
CCAAAAGGACAAGAGATCAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGG
AAAAACTTTAAACTTTTCTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTC
TCTTCCGTTTTGAAAAAGAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCC
AGATATTGCCCCATCTCAAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCC
TGAAATCCTGGTGGGGATGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTT
GAATGTTAATTGCATTTTCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATT

>18676_18676_1_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000262061_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_2_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000455864_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14904nt_BP=43nt
ACGTCGGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAATTCC
CAGAAGAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAAAGGAGATG
CAGATCACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGGAGAAGTGG
CAAGACGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCACAAGTCAC
CTCCAAATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATTTGAAAGCA
CAATTCTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTCCAAGTGCA
AGCTGAAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTGGAGCGAGT
TAATTCCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAGTCAGAGTT
CCTATGAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTAGCAACGAG
AATGACCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTAATTACTGA
GCACAAGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATTTAGAAAGC
TTTAAGTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAGTCAGTTCA
CTTGCGCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGACACCTATTG
TGAAGTCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGACGCACACT
CAGGAGGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGTGTCCTTGG
TTGATCAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTCCTCATCCA
TCCCATTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGACTGTCATC
TAGTCCTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAGCAGAATAC
TGCAAACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCAACTCCGAA
TGGCATTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGGGGTGGCTT
TGCCACACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCATATTTACC
AGTGAATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGACTGACTTTT
TTATGAATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAATAAATAAAT
CCGTAAATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGTGTTCAAAC
AGACCTCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGCTGCTGCTT
CATTTGACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAACAGAGCAA
CAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCTAAAATACT
AATAGCGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTATTGTTTCAT
TTCAATTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGATATTGAACA
GTTCTCTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTATGTTCAGA
GTCTCATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACCAAAGAGTT
TATAGAGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAAAAATAATT
GCCAGTTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAAATACATAT
ATAGATCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCTAAGTATTC
GGTTCAGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATGGAAGTTTC
TGGGACAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATTTGTATTCG
GAGTCATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCCTGACAGTG
GGGTGCTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATCTGTTCTCC
AGGAGCTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCCAACTCCTG
TTGCAATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCACTGGGGTGG
GCAGTGGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAGTCCTGCCC
CTAGAGAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAATGTGACTCT
CCACAATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCCATGTTTCC
TTTGTCAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAAAGAGTCCT
TGTGACATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTCTTTGACAT
ACTAATCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAACATTGGTC
AAACCAGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCTTTAATAAA
TGTCTCATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGTGTATCTAT
ACAGTTATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGGTAATAGAA
TTTAACCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAGTTTAGTAT
CCATTACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCAAATTTCAC
ATTCTTGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCTTGCATTGT
TTTTGTTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATACATTTCTT
TTTTTAAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGCTTGCACCA
TGCATAAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCCTTTTCCCC
CTGCAGGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAATGTAAATCT
GATACACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTTGTCTATAC
TGGGCACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTCCCCACTTT
TGAAAATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACTCGGATTTT
CAGGAGTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTATTAAAAAGT
GGAGAAAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTAACAGGTTA
GAGCTGACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGGTAGATGAA
GAAGGGGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGCTAAGATCA
AGTCACCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGTTGGTTGTA
TAAGTCTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAAGGTCGGGG
AGGGAAAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGGACCTCACA
TAGGTAGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTCACACACCA
AAATGACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTAACCAGCTA
ATACCTTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCAGCAAGCAT
TTCATGTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATACATATTTTA
ACATGTGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGACAAGCTTCA
TACGTATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATTGTTTTCAT
TATTTATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATTTCATTTGG
GCATATCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATGACTTCGGT
TGAATAGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGAAAAAACAA
AGAAAAAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGGTACTGCGG
TCTTGGGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAAGTTTTAGA
GGTTATAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTCTGCCCCAC
CCCACAGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAATTAGTTCCT
AGTACATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAAACCTAGAC
CAATGGTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTACAGACAGG
GAAGAAATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTTTTAAATTA
TTTAACTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGTAACTTATT
TATTTAACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTTGTTTGCTG
TCAGAACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACCCTGCTTCA
CCAGCCTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTTACACTAGC
TGCTTCCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAAAAATGAAA
AACTTTCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACCAAAGATAC
CAAAGATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGTACAGCCAC
AGCTCAGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTATATGTTTGC
TGTCTGCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGGAAACTGGT
TGGAAATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACAGAAGCTCT
GACCATTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTATCCAAATCA
AATAACTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGCATGAGAGC
GGTCCCACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTGTAAAATTA
GTCACAAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACTAGGGCTCA
TACGGGATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTATAGATAACT
TTTTAATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCAAGAAAGGG
AACTTGACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCTAAGCCAAC
TCTGTATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAATTACAGAG
GAATATGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAAGTTTCTTT
AGATTCCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCTTTTGACCA
AATGGGTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAATGTAGTTAT
TTTGAGCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACAAAGCATAG
CTAGTAGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCTATGTGAAA
GTTCCCTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTACATTGCTTT
GGTTTTCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGCAGCAGAGC
TCCCTATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGCCTGAACAC
AGAAAACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACGGGACGAGT
GCCTTGCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCTTCAACTGG
GCCTCCATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAATACCAAAGG
TTCTTTCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAACCTGGGCA
TGTTGGCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTATTATAGCGT
ATGTAATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGGTTGTGCTT
TTGTAATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGGGAAAGTTG
CAGAATGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTATTTTCTAC
ATTTGTGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTATAATTTTAT
GCATGAGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTTGGTTCAAT
GGACTTTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACACAGTTCAG
CCTCAGACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATGAGTCACAT
TGAATTGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCCTCATAACC
CAAATATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGGAGTTATTT
TGGCTTTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCTCTGCTTGG
GAATGGCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCAATATTACT
AACTCTTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGCAGCCATTT
CCCAAAACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAACAATGTTC
CATCTACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTATCTGAGGCC
TCTATATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCTCCAGTTTC
ATATTTCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTAGGGAACCT
TGGTTGAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTATATTGGGA
ACGTGCTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATATAGTCTTT
TTATTTTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGATTGTAATAG
TGTTTAATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACAAACCCACA
AACTGTTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTGAGACATGA
GTGTACCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAACCCAAGGT
ATATTTTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTCCAGACAAC
TGAAGTAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTTGGAGACAC
ATAACTACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCAGGTCATGG
GCTGGAAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCTCACTCTCT
CTGGACTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGGCAAGAAAA
AGAAAATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATTGCAGCCCA
TCTGGTGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAGTGGGGCTC
TTCCACATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTAGAAAACAA
AGAAAGGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAAGAGGGAAA
AGGAGACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTCTTGGGCGA
CAGGCTGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAAAAAGTTGT
AGAGTTTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGGAAAGTTTT
TTCAGATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAACAGATACTT
CCTTGAAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTGAAATGTTG
TAAAACACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTAGATGCAGG
GACTGAGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAAGAGCAGTT
CAGTCTTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTTCTCTTCTT
CATCTTTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATTTTTCCACC
CAGACAATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAAAGTGAGTG
AAAACAAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGACCCTGGCCT
CAGATGTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATACTGTTGACT
GCTTGATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAAAGTTTCAA
AATTTAAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTACTCTGCCAC
CTGCCTTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAAAAGGACAA
GAGATCAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAAACTTTAAA
CTTTTCTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTTCCGTTTTG
AAAAAGAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGATATTGCCCC
ATCTCAAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAAATCCTGGT
GGGGATGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAATGTTAATTG
CATTTTCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTATCATTAAA

>18676_18676_2_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000455864_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_3_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000549116_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14899nt_BP=38nt
GGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAATTCCCAGAA
GAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAAAGGAGATGCAGAT
CACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGGAGAAGTGGCAAGA
CGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCACAAGTCACCTCCA
AATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATTTGAAAGCACAATT
CTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTCCAAGTGCAAGCTG
AAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTGGAGCGAGTTAATT
CCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAGTCAGAGTTCCTAT
GAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTAGCAACGAGAATGA
CCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTAATTACTGAGCACA
AGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATTTAGAAAGCTTTAA
GTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAGTCAGTTCACTTGC
GCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGACACCTATTGTGAAG
TCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGACGCACACTCAGGA
GGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGTGTCCTTGGTTGAT
CAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTCCTCATCCATCCCA
TTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGACTGTCATCTAGTC
CTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAGCAGAATACTGCAA
ACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCAACTCCGAATGGCA
TTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGGGGTGGCTTTGCCA
CACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCATATTTACCAGTGA
ATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGACTGACTTTTTTATG
AATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAATAAATAAATCCGTA
AATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGTGTTCAAACAGACC
TCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGCTGCTGCTTCATTT
GACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAACAGAGCAACAGAA
ACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCTAAAATACTAATAG
CGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTATTGTTTCATTTCAA
TTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGATATTGAACAGTTCT
CTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTATGTTCAGAGTCTC
ATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACCAAAGAGTTTATAG
AGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAAAAATAATTGCCAG
TTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAAATACATATATAGA
TCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCTAAGTATTCGGTTC
AGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATGGAAGTTTCTGGGA
CAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATTTGTATTCGGAGTC
ATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCCTGACAGTGGGGTG
CTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATCTGTTCTCCAGGAG
CTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCCAACTCCTGTTGCA
ATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCACTGGGGTGGGCAGT
GGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAGTCCTGCCCCTAGA
GAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAATGTGACTCTCCACA
ATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCCATGTTTCCTTTGT
CAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAAAGAGTCCTTGTGA
CATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTCTTTGACATACTAA
TCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAACATTGGTCAAACC
AGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCTTTAATAAATGTCT
CATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGTGTATCTATACAGT
TATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGGTAATAGAATTTAA
CCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAGTTTAGTATCCATT
ACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCAAATTTCACATTCT
TGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCTTGCATTGTTTTTG
TTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATACATTTCTTTTTTT
AAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGCTTGCACCATGCAT
AAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCCTTTTCCCCCTGCA
GGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAATGTAAATCTGATAC
ACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTTGTCTATACTGGGC
ACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTCCCCACTTTTGAAA
ATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACTCGGATTTTCAGGA
GTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTATTAAAAAGTGGAGA
AAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTAACAGGTTAGAGCT
GACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGGTAGATGAAGAAGG
GGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGCTAAGATCAAGTCA
CCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGTTGGTTGTATAAGT
CTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAAGGTCGGGGAGGGA
AAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGGACCTCACATAGGT
AGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTCACACACCAAAATG
ACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTAACCAGCTAATACC
TTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCAGCAAGCATTTCAT
GTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATACATATTTTAACATG
TGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGACAAGCTTCATACGT
ATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATTGTTTTCATTATTT
ATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATTTCATTTGGGCATA
TCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATGACTTCGGTTGAAT
AGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGAAAAAACAAAGAAA
AAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGGTACTGCGGTCTTG
GGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAAGTTTTAGAGGTTA
TAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTCTGCCCCACCCCAC
AGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAATTAGTTCCTAGTAC
ATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAAACCTAGACCAATG
GTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTACAGACAGGGAAGA
AATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTTTTAAATTATTTAA
CTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGTAACTTATTTATTT
AACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTTGTTTGCTGTCAGA
ACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACCCTGCTTCACCAGC
CTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTTACACTAGCTGCTT
CCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAAAAATGAAAAACTT
TCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACCAAAGATACCAAAG
ATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGTACAGCCACAGCTC
AGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTATATGTTTGCTGTCT
GCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGGAAACTGGTTGGAA
ATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACAGAAGCTCTGACCA
TTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTATCCAAATCAAATAA
CTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGCATGAGAGCGGTCC
CACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTGTAAAATTAGTCAC
AAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACTAGGGCTCATACGG
GATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTATAGATAACTTTTTA
ATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCAAGAAAGGGAACTT
GACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCTAAGCCAACTCTGT
ATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAATTACAGAGGAATA
TGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAAGTTTCTTTAGATT
CCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCTTTTGACCAAATGG
GTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAATGTAGTTATTTTGA
GCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACAAAGCATAGCTAGT
AGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCTATGTGAAAGTTCC
CTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTACATTGCTTTGGTTT
TCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGCAGCAGAGCTCCCT
ATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGCCTGAACACAGAAA
ACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACGGGACGAGTGCCTT
GCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCTTCAACTGGGCCTC
CATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAATACCAAAGGTTCTT
TCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAACCTGGGCATGTTG
GCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTATTATAGCGTATGTA
ATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGGTTGTGCTTTTGTA
ATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGGGAAAGTTGCAGAA
TGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTATTTTCTACATTTG
TGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTATAATTTTATGCATG
AGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTTGGTTCAATGGACT
TTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACACAGTTCAGCCTCA
GACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATGAGTCACATTGAAT
TGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCCTCATAACCCAAAT
ATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGGAGTTATTTTGGCT
TTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCTCTGCTTGGGAATG
GCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCAATATTACTAACTC
TTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGCAGCCATTTCCCAA
AACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAACAATGTTCCATCT
ACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTATCTGAGGCCTCTAT
ATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCTCCAGTTTCATATT
TCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTAGGGAACCTTGGTT
GAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTATATTGGGAACGTG
CTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATATAGTCTTTTTATT
TTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGATTGTAATAGTGTTT
AATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACAAACCCACAAACTG
TTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTGAGACATGAGTGTA
CCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAACCCAAGGTATATT
TTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTCCAGACAACTGAAG
TAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTTGGAGACACATAAC
TACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCAGGTCATGGGCTGG
AAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCTCACTCTCTCTGGA
CTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGGCAAGAAAAAGAAA
ATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATTGCAGCCCATCTGG
TGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAGTGGGGCTCTTCCA
CATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTAGAAAACAAAGAAA
GGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAAGAGGGAAAAGGAG
ACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTCTTGGGCGACAGGC
TGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAAAAAGTTGTAGAGT
TTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGGAAAGTTTTTTCAG
ATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAACAGATACTTCCTTG
AAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTGAAATGTTGTAAAA
CACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTAGATGCAGGGACTG
AGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAAGAGCAGTTCAGTC
TTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTTCTCTTCTTCATCT
TTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATTTTTCCACCCAGAC
AATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAAAGTGAGTGAAAAC
AAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGACCCTGGCCTCAGAT
GTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATACTGTTGACTGCTTG
ATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAAAGTTTCAAAATTT
AAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTACTCTGCCACCTGCC
TTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAAAAGGACAAGAGAT
CAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAAACTTTAAACTTTT
CTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTTCCGTTTTGAAAAA
GAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGATATTGCCCCATCTC
AAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAAATCCTGGTGGGGA
TGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAATGTTAATTGCATTT
TCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTATCATTAAATGGTA

>18676_18676_3_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000549116_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_4_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000551779_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14892nt_BP=31nt
GCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAATTCCCAGAAGAAGTCC
CGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAAAGGAGATGCAGATCACCATT
TCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGGAGAAGTGGCAAGACGATCTG
AGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCACAAGTCACCTCCAAATGAGG
ACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATTTGAAAGCACAATTCTCTTGC
AAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTCCAAGTGCAAGCTGAAAAATT
AATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTGGAGCGAGTTAATTCCAGTAT
GGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAGTCAGAGTTCCTATGAGTAAC
AATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTAGCAACGAGAATGACCTCATT
TGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTAATTACTGAGCACAAGTTTTA
AATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATTTAGAAAGCTTTAAGTTGATC
CAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAGTCAGTTCACTTGCGCTCAAA
GTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGACACCTATTGTGAAGTCATTAG
GGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGACGCACACTCAGGAGGCCAAT
TTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGTGTCCTTGGTTGATCAGTCAT
CTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTCCTCATCCATCCCATTAGTAG
GGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGACTGTCATCTAGTCCTAAATC
TCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAGCAGAATACTGCAAACCAAAG
ACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCAACTCCGAATGGCATTCAGCT
CTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGGGGTGGCTTTGCCACACCAGT
TGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCATATTTACCAGTGAATGGCCC
CGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGACTGACTTTTTTATGAATTACT
TAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAATAAATAAATCCGTAAATCAAT
GGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGTGTTCAAACAGACCTCTTGGG
ACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGCTGCTGCTTCATTTGACAACT
CACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAACAGAGCAACAGAAACCTCAA
CAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCTAAAATACTAATAGCGCCATT
GAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTATTGTTTCATTTCAATTTTGTC
TTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGATATTGAACAGTTCTCTCTGCT
CAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTATGTTCAGAGTCTCATCATCA
GGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACCAAAGAGTTTATAGAGGAATT
TACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAAAAATAATTGCCAGTTTCTAC
TTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAAATACATATATAGATCAACTT
GACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCTAAGTATTCGGTTCAGAATTT
TTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATGGAAGTTTCTGGGACAGGTTT
AAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATTTGTATTCGGAGTCATCTCTA
TTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCCTGACAGTGGGGTGCTCATCT
TCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATCTGTTCTCCAGGAGCTGCCCT
GTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCCAACTCCTGTTGCAATGGGTT
GATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCACTGGGGTGGGCAGTGGTGTTG
GGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAGTCCTGCCCCTAGAGAGCCCC
ATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAATGTGACTCTCCACAATTTTTA
TAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCCATGTTTCCTTTGTCAAAGGA
CTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAAAGAGTCCTTGTGACATGTGT
CCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTCTTTGACATACTAATCTCAGC
GTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAACATTGGTCAAACCAGTCCTC
TGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCTTTAATAAATGTCTCATTCCA
GATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGTGTATCTATACAGTTATGTAT
CAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGGTAATAGAATTTAACCCAGTG
AGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAGTTTAGTATCCATTACCTCAA
TCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCAAATTTCACATTCTTGAGGCA
ACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCTTGCATTGTTTTTGTTTTAAT
GTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATACATTTCTTTTTTTAAAGGAA
ACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGCTTGCACCATGCATAAAGGTG
CAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCCTTTTCCCCCTGCAGGCTCTT
GGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAATGTAAATCTGATACACACACA
CTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTTGTCTATACTGGGCACCCACC
TACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTCCCCACTTTTGAAAATGTTGG
TAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACTCGGATTTTCAGGAGTTTGAA
TAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTATTAAAAAGTGGAGAAAAAGAT
AATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTAACAGGTTAGAGCTGACTTTT
TGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGGTAGATGAAGAAGGGGTAGAG
CTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGCTAAGATCAAGTCACCCCTGA
AACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGTTGGTTGTATAAGTCTCATAA
GATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAAGGTCGGGGAGGGAAAGAGGG
GAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGGACCTCACATAGGTAGATACA
GAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTCACACACCAAAATGACTCTGA
CAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTAACCAGCTAATACCTTTTCTA
GTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCAGCAAGCATTTCATGTAGCAT
AAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATACATATTTTAACATGTGTTCTC
ATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGACAAGCTTCATACGTATATACT
GTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATTGTTTTCATTATTTATTGTAA
CATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATTTCATTTGGGCATATCCAAGA
TAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATGACTTCGGTTGAATAGCTTTA
TTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGAAAAAACAAAGAAAAAGAAGA
AAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGGTACTGCGGTCTTGGGGAGAC
TGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAAGTTTTAGAGGTTATAATTTC
CTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTCTGCCCCACCCCACAGAATGC
TTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAATTAGTTCCTAGTACATAAATG
TATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAAACCTAGACCAATGGTGCATC
AGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTACAGACAGGGAAGAAATACAG
GTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTTTTAAATTATTTAACTTAAGT
TCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGTAACTTATTTATTTAACTTAT
TCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTTGTTTGCTGTCAGAACAACAG
AGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACCCTGCTTCACCAGCCTGGATT
TCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTTACACTAGCTGCTTCCAAGAA
TGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAAAAATGAAAAACTTTCTATTT
CTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACCAAAGATACCAAAGATTTCTT
TCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGTACAGCCACAGCTCAGATACC
CCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTATATGTTTGCTGTCTGCTCGAC
ATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGGAAACTGGTTGGAAATGGCCT
TCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACAGAAGCTCTGACCATTGAGTA
GTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTATCCAAATCAAATAACTCTTGA
GAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGCATGAGAGCGGTCCCACATTG
ACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTGTAAAATTAGTCACAAGCATT
TTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACTAGGGCTCATACGGGATTTTT
GCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTATAGATAACTTTTTAATTCAGT
AGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCAAGAAAGGGAACTTGACCACC
ATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCTAAGCCAACTCTGTATTTATG
AGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAATTACAGAGGAATATGCCAGT
TTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAAGTTTCTTTAGATTCCATTAA
ATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCTTTTGACCAAATGGGTTTTAG
ACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAATGTAGTTATTTTGAGCTTTTA
AAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACAAAGCATAGCTAGTAGAGGAA
TATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCTATGTGAAAGTTCCCTCCTGT
CCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTACATTGCTTTGGTTTTCTTCCT
AAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGCAGCAGAGCTCCCTATAAGTG
AACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGCCTGAACACAGAAAACATCCC
CACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACGGGACGAGTGCCTTGCTTGAA
CCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCTTCAACTGGGCCTCCATACAG
TCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAATACCAAAGGTTCTTTCTCTAT
GTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAACCTGGGCATGTTGGCAATGC
AGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTATTATAGCGTATGTAATAAATT
ATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGGTTGTGCTTTTGTAATAGATG
AAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGGGAAAGTTGCAGAATGAGCCC
AAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTATTTTCTACATTTGTGCCACT
TGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTATAATTTTATGCATGAGGCTAA
AAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTTGGTTCAATGGACTTTATTTA
TGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACACAGTTCAGCCTCAGACGGTG
GTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATGAGTCACATTGAATTGGGTTC
CAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCCTCATAACCCAAATATATCAC
CGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGGAGTTATTTTGGCTTTATGCT
CATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCTCTGCTTGGGAATGGCTATTT
TTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCAATATTACTAACTCTTCTCTG
CCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGCAGCCATTTCCCAAAACTTCA
CATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAACAATGTTCCATCTACCATCT
AAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTATCTGAGGCCTCTATATGTCAA
AACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCTCCAGTTTCATATTTCCCAAA
CCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTAGGGAACCTTGGTTGAAAAGC
AGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTATATTGGGAACGTGCTCTCGT
GAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATATAGTCTTTTTATTTTTCTCT
TATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGATTGTAATAGTGTTTAATCTTC
CAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACAAACCCACAAACTGTTCCTCT
TAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTGAGACATGAGTGTACCCAGCC
CTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAACCCAAGGTATATTTTGTTAT
GCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTCCAGACAACTGAAGTAGCTAC
ATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTTGGAGACACATAACTACAAAA
TTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCAGGTCATGGGCTGGAAGGTAG
GTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCTCACTCTCTCTGGACTCCAAC
ACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGGCAAGAAAAAGAAAATAGTAA
CCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATTGCAGCCCATCTGGTGGCTTT
ACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAGTGGGGCTCTTCCACATCAGA
AGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTAGAAAACAAAGAAAGGTATGG
AATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAAGAGGGAAAAGGAGACCCCAC
TATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTCTTGGGCGACAGGCTGAATCA
CAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAAAAAGTTGTAGAGTTTGAGGT
TTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGGAAAGTTTTTTCAGATTATGA
CAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAACAGATACTTCCTTGAAGGTAG
AATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTGAAATGTTGTAAAACACCTGG
CATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTAGATGCAGGGACTGAGATGAT
ACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAAGAGCAGTTCAGTCTTTTCTC
CCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTTCTCTTCTTCATCTTTGCATT
TCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATTTTTCCACCCAGACAATACTT
TATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAAAGTGAGTGAAAACAAGTTCC
AGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGACCCTGGCCTCAGATGTGTTTA
TTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATACTGTTGACTGCTTGATGGTAT
TGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAAAGTTTCAAAATTTAAAAAGG
GACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTACTCTGCCACCTGCCTTCCAGG
TAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAAAAGGACAAGAGATCAGAGAG
TCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAAACTTTAAACTTTTCTTTTCA
GTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTTCCGTTTTGAAAAAGAAAACC
CACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGATATTGCCCCATCTCAAACATG
TTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAAATCCTGGTGGGGATGAGGAT
CACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAATGTTAATTGCATTTTCAGTTT
TGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTATCATTAAATGGTAGTGCTGT

>18676_18676_4_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000551779_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_5_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000552218_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14912nt_BP=51nt
GCGGCTCCACGTCGGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGA
ACAATTCCCAGAAGAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAA
AGGAGATGCAGATCACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGG
AGAAGTGGCAAGACGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCA
CAAGTCACCTCCAAATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATT
TGAAAGCACAATTCTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTC
CAAGTGCAAGCTGAAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTG
GAGCGAGTTAATTCCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAG
TCAGAGTTCCTATGAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTA
GCAACGAGAATGACCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTA
ATTACTGAGCACAAGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATT
TAGAAAGCTTTAAGTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAG
TCAGTTCACTTGCGCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGAC
ACCTATTGTGAAGTCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGA
CGCACACTCAGGAGGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGT
GTCCTTGGTTGATCAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTC
CTCATCCATCCCATTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGA
CTGTCATCTAGTCCTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAG
CAGAATACTGCAAACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCA
ACTCCGAATGGCATTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGG
GGTGGCTTTGCCACACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCA
TATTTACCAGTGAATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGAC
TGACTTTTTTATGAATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAAT
AAATAAATCCGTAAATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGT
GTTCAAACAGACCTCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGC
TGCTGCTTCATTTGACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAA
CAGAGCAACAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCT
AAAATACTAATAGCGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTAT
TGTTTCATTTCAATTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGAT
ATTGAACAGTTCTCTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTA
TGTTCAGAGTCTCATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACC
AAAGAGTTTATAGAGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAA
AAATAATTGCCAGTTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAA
ATACATATATAGATCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCT
AAGTATTCGGTTCAGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATG
GAAGTTTCTGGGACAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATT
TGTATTCGGAGTCATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCC
TGACAGTGGGGTGCTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATC
TGTTCTCCAGGAGCTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCC
AACTCCTGTTGCAATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCAC
TGGGGTGGGCAGTGGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAG
TCCTGCCCCTAGAGAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAAT
GTGACTCTCCACAATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCC
ATGTTTCCTTTGTCAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAA
AGAGTCCTTGTGACATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTC
TTTGACATACTAATCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAA
CATTGGTCAAACCAGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCT
TTAATAAATGTCTCATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGT
GTATCTATACAGTTATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGG
TAATAGAATTTAACCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAG
TTTAGTATCCATTACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCA
AATTTCACATTCTTGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCT
TGCATTGTTTTTGTTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATA
CATTTCTTTTTTTAAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGC
TTGCACCATGCATAAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCC
TTTTCCCCCTGCAGGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAAT
GTAAATCTGATACACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTT
GTCTATACTGGGCACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTC
CCCACTTTTGAAAATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACT
CGGATTTTCAGGAGTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTAT
TAAAAAGTGGAGAAAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTA
ACAGGTTAGAGCTGACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGG
TAGATGAAGAAGGGGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGC
TAAGATCAAGTCACCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGT
TGGTTGTATAAGTCTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAA
GGTCGGGGAGGGAAAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGG
ACCTCACATAGGTAGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTC
ACACACCAAAATGACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTA
ACCAGCTAATACCTTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCA
GCAAGCATTTCATGTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATAC
ATATTTTAACATGTGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGAC
AAGCTTCATACGTATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATT
GTTTTCATTATTTATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATT
TCATTTGGGCATATCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATG
ACTTCGGTTGAATAGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGA
AAAAACAAAGAAAAAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGG
TACTGCGGTCTTGGGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAA
GTTTTAGAGGTTATAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTC
TGCCCCACCCCACAGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAAT
TAGTTCCTAGTACATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAA
ACCTAGACCAATGGTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTA
CAGACAGGGAAGAAATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTT
TTAAATTATTTAACTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGT
AACTTATTTATTTAACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTT
GTTTGCTGTCAGAACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACC
CTGCTTCACCAGCCTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTT
ACACTAGCTGCTTCCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAA
AAATGAAAAACTTTCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACC
AAAGATACCAAAGATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGT
ACAGCCACAGCTCAGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTAT
ATGTTTGCTGTCTGCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGG
AAACTGGTTGGAAATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACA
GAAGCTCTGACCATTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTAT
CCAAATCAAATAACTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGC
ATGAGAGCGGTCCCACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTG
TAAAATTAGTCACAAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACT
AGGGCTCATACGGGATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTAT
AGATAACTTTTTAATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCA
AGAAAGGGAACTTGACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCT
AAGCCAACTCTGTATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAA
TTACAGAGGAATATGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAA
GTTTCTTTAGATTCCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCT
TTTGACCAAATGGGTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAAT
GTAGTTATTTTGAGCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACA
AAGCATAGCTAGTAGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCT
ATGTGAAAGTTCCCTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTAC
ATTGCTTTGGTTTTCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGC
AGCAGAGCTCCCTATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGC
CTGAACACAGAAAACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACG
GGACGAGTGCCTTGCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCT
TCAACTGGGCCTCCATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAAT
ACCAAAGGTTCTTTCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAA
CCTGGGCATGTTGGCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTAT
TATAGCGTATGTAATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGG
TTGTGCTTTTGTAATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGG
GAAAGTTGCAGAATGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTA
TTTTCTACATTTGTGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTAT
AATTTTATGCATGAGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTT
GGTTCAATGGACTTTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACA
CAGTTCAGCCTCAGACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATG
AGTCACATTGAATTGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCC
TCATAACCCAAATATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGG
AGTTATTTTGGCTTTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCT
CTGCTTGGGAATGGCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCA
ATATTACTAACTCTTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGC
AGCCATTTCCCAAAACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAA
CAATGTTCCATCTACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTAT
CTGAGGCCTCTATATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCT
CCAGTTTCATATTTCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTA
GGGAACCTTGGTTGAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTA
TATTGGGAACGTGCTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATA
TAGTCTTTTTATTTTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGAT
TGTAATAGTGTTTAATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACA
AACCCACAAACTGTTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTG
AGACATGAGTGTACCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAA
CCCAAGGTATATTTTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTC
CAGACAACTGAAGTAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTT
GGAGACACATAACTACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCA
GGTCATGGGCTGGAAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCT
CACTCTCTCTGGACTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGG
CAAGAAAAAGAAAATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATT
GCAGCCCATCTGGTGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAG
TGGGGCTCTTCCACATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTA
GAAAACAAAGAAAGGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAA
GAGGGAAAAGGAGACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTC
TTGGGCGACAGGCTGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAA
AAAGTTGTAGAGTTTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGG
AAAGTTTTTTCAGATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAAC
AGATACTTCCTTGAAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTG
AAATGTTGTAAAACACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTA
GATGCAGGGACTGAGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAA
GAGCAGTTCAGTCTTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTT
CTCTTCTTCATCTTTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATT
TTTCCACCCAGACAATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAA
AGTGAGTGAAAACAAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGAC
CCTGGCCTCAGATGTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATAC
TGTTGACTGCTTGATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAA
AGTTTCAAAATTTAAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTAC
TCTGCCACCTGCCTTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAA
AAGGACAAGAGATCAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAA
ACTTTAAACTTTTCTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTT
CCGTTTTGAAAAAGAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGAT
ATTGCCCCATCTCAAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAA
ATCCTGGTGGGGATGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAAT
GTTAATTGCATTTTCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTA

>18676_18676_5_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000552218_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_6_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000552362_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14904nt_BP=43nt
ACGTCGGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAATTCC
CAGAAGAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAAAGGAGATG
CAGATCACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGGAGAAGTGG
CAAGACGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCACAAGTCAC
CTCCAAATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATTTGAAAGCA
CAATTCTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTCCAAGTGCA
AGCTGAAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTGGAGCGAGT
TAATTCCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAGTCAGAGTT
CCTATGAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTAGCAACGAG
AATGACCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTAATTACTGA
GCACAAGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATTTAGAAAGC
TTTAAGTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAGTCAGTTCA
CTTGCGCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGACACCTATTG
TGAAGTCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGACGCACACT
CAGGAGGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGTGTCCTTGG
TTGATCAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTCCTCATCCA
TCCCATTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGACTGTCATC
TAGTCCTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAGCAGAATAC
TGCAAACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCAACTCCGAA
TGGCATTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGGGGTGGCTT
TGCCACACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCATATTTACC
AGTGAATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGACTGACTTTT
TTATGAATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAATAAATAAAT
CCGTAAATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGTGTTCAAAC
AGACCTCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGCTGCTGCTT
CATTTGACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAACAGAGCAA
CAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCTAAAATACT
AATAGCGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTATTGTTTCAT
TTCAATTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGATATTGAACA
GTTCTCTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTATGTTCAGA
GTCTCATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACCAAAGAGTT
TATAGAGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAAAAATAATT
GCCAGTTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAAATACATAT
ATAGATCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCTAAGTATTC
GGTTCAGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATGGAAGTTTC
TGGGACAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATTTGTATTCG
GAGTCATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCCTGACAGTG
GGGTGCTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATCTGTTCTCC
AGGAGCTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCCAACTCCTG
TTGCAATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCACTGGGGTGG
GCAGTGGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAGTCCTGCCC
CTAGAGAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAATGTGACTCT
CCACAATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCCATGTTTCC
TTTGTCAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAAAGAGTCCT
TGTGACATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTCTTTGACAT
ACTAATCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAACATTGGTC
AAACCAGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCTTTAATAAA
TGTCTCATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGTGTATCTAT
ACAGTTATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGGTAATAGAA
TTTAACCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAGTTTAGTAT
CCATTACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCAAATTTCAC
ATTCTTGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCTTGCATTGT
TTTTGTTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATACATTTCTT
TTTTTAAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGCTTGCACCA
TGCATAAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCCTTTTCCCC
CTGCAGGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAATGTAAATCT
GATACACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTTGTCTATAC
TGGGCACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTCCCCACTTT
TGAAAATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACTCGGATTTT
CAGGAGTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTATTAAAAAGT
GGAGAAAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTAACAGGTTA
GAGCTGACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGGTAGATGAA
GAAGGGGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGCTAAGATCA
AGTCACCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGTTGGTTGTA
TAAGTCTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAAGGTCGGGG
AGGGAAAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGGACCTCACA
TAGGTAGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTCACACACCA
AAATGACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTAACCAGCTA
ATACCTTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCAGCAAGCAT
TTCATGTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATACATATTTTA
ACATGTGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGACAAGCTTCA
TACGTATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATTGTTTTCAT
TATTTATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATTTCATTTGG
GCATATCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATGACTTCGGT
TGAATAGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGAAAAAACAA
AGAAAAAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGGTACTGCGG
TCTTGGGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAAGTTTTAGA
GGTTATAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTCTGCCCCAC
CCCACAGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAATTAGTTCCT
AGTACATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAAACCTAGAC
CAATGGTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTACAGACAGG
GAAGAAATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTTTTAAATTA
TTTAACTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGTAACTTATT
TATTTAACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTTGTTTGCTG
TCAGAACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACCCTGCTTCA
CCAGCCTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTTACACTAGC
TGCTTCCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAAAAATGAAA
AACTTTCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACCAAAGATAC
CAAAGATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGTACAGCCAC
AGCTCAGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTATATGTTTGC
TGTCTGCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGGAAACTGGT
TGGAAATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACAGAAGCTCT
GACCATTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTATCCAAATCA
AATAACTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGCATGAGAGC
GGTCCCACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTGTAAAATTA
GTCACAAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACTAGGGCTCA
TACGGGATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTATAGATAACT
TTTTAATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCAAGAAAGGG
AACTTGACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCTAAGCCAAC
TCTGTATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAATTACAGAG
GAATATGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAAGTTTCTTT
AGATTCCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCTTTTGACCA
AATGGGTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAATGTAGTTAT
TTTGAGCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACAAAGCATAG
CTAGTAGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCTATGTGAAA
GTTCCCTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTACATTGCTTT
GGTTTTCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGCAGCAGAGC
TCCCTATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGCCTGAACAC
AGAAAACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACGGGACGAGT
GCCTTGCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCTTCAACTGG
GCCTCCATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAATACCAAAGG
TTCTTTCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAACCTGGGCA
TGTTGGCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTATTATAGCGT
ATGTAATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGGTTGTGCTT
TTGTAATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGGGAAAGTTG
CAGAATGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTATTTTCTAC
ATTTGTGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTATAATTTTAT
GCATGAGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTTGGTTCAAT
GGACTTTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACACAGTTCAG
CCTCAGACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATGAGTCACAT
TGAATTGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCCTCATAACC
CAAATATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGGAGTTATTT
TGGCTTTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCTCTGCTTGG
GAATGGCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCAATATTACT
AACTCTTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGCAGCCATTT
CCCAAAACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAACAATGTTC
CATCTACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTATCTGAGGCC
TCTATATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCTCCAGTTTC
ATATTTCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTAGGGAACCT
TGGTTGAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTATATTGGGA
ACGTGCTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATATAGTCTTT
TTATTTTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGATTGTAATAG
TGTTTAATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACAAACCCACA
AACTGTTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTGAGACATGA
GTGTACCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAACCCAAGGT
ATATTTTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTCCAGACAAC
TGAAGTAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTTGGAGACAC
ATAACTACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCAGGTCATGG
GCTGGAAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCTCACTCTCT
CTGGACTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGGCAAGAAAA
AGAAAATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATTGCAGCCCA
TCTGGTGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAGTGGGGCTC
TTCCACATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTAGAAAACAA
AGAAAGGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAAGAGGGAAA
AGGAGACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTCTTGGGCGA
CAGGCTGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAAAAAGTTGT
AGAGTTTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGGAAAGTTTT
TTCAGATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAACAGATACTT
CCTTGAAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTGAAATGTTG
TAAAACACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTAGATGCAGG
GACTGAGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAAGAGCAGTT
CAGTCTTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTTCTCTTCTT
CATCTTTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATTTTTCCACC
CAGACAATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAAAGTGAGTG
AAAACAAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGACCCTGGCCT
CAGATGTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATACTGTTGACT
GCTTGATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAAAGTTTCAA
AATTTAAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTACTCTGCCAC
CTGCCTTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAAAAGGACAA
GAGATCAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAAACTTTAAA
CTTTTCTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTTCCGTTTTG
AAAAAGAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGATATTGCCCC
ATCTCAAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAAATCCTGGT
GGGGATGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAATGTTAATTG
CATTTTCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTATCATTAAA

>18676_18676_6_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000552362_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------
>18676_18676_7_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000553231_ONECUT2_chr18_55143669_ENST00000491143_length(transcript)=14904nt_BP=43nt
ACGTCGGCACCAGCTGCGGGGCAAGATGGAGGCGCTGATTTTGCGTGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAATTCC
CAGAAGAAGTCCCGCCTGGTGTTCACTGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAGAACAAACGCCCGTCAAAGGAGATG
CAGATCACCATTTCCCAGCAGCTGGGCCTGGAGCTCACAACCGTCAGCAACTTCTTCATGAACGCCCGGCGCCGCAGCCTGGAGAAGTGG
CAAGACGATCTGAGCACAGGGGGCTCCTCGTCCACCTCCAGCACGTGTACCAAAGCATGATGGAAGGACTCTCACTTGGGCACAAGTCAC
CTCCAAATGAGGACAACAGATACCAAAAGAAAACAAAGGAAAAAGACACCGGATTCCTAGCTGGGGCCCTTCACTGGTGATTTGAAAGCA
CAATTCTCTTGCAAAGAAACTTATATTCTAGCTGTAATCATAGGCCAGGTGTTCTTCTTTTGTTTTTAATGGCTATGGAGTCCAAGTGCA
AGCTGAAAAATTAATCTCTTAGAACCAGACACTGTTCTCTGAGCATGCTAAGCATCCCAGAAACCCAAATGGGGCCTTCCTGGAGCGAGT
TAATTCCAGTATGGTGTCAACCAAGCTCGGGATTGCTTAAAATATCATCCATCCCACTTCAGGTCCTGTCAGCTTCTTGCAGTCAGAGTT
CCTATGAGTAACAATAGGAGTTTGGCCTATGTAAGGACTCTGAGTTTAGGCTTCCAAGATACAACAATAAGAGAAGAATCTAGCAACGAG
AATGACCTCATTTGCTTTCCACATGCTTAGCCTCATTATACCATGTTATGTCCAAGTTCACAGCCACAACATCAGAATGGTAATTACTGA
GCACAAGTTTTAAATATGGACGTTAAAAAAAAAAATCCAAGGACCTGTTTTTCCAACCCAGACATCTTTTCATTGAATGATTTAGAAAGC
TTTAAGTTGATCCAGCTTACAATTTTTTTTTTCTTTACCTCCTGGAAATCTCATATGGTCTTGGATCCGTCAAAAAAACCAGTCAGTTCA
CTTGCGCTCAAAGTATCAAGCACAACAAAGATAAACAGAAGTGAGGAAGGTTCTGGGTTCACTACATCTGGATTTTCAAGACACCTATTG
TGAAGTCATTAGGGAATTGATGAGAATATGGCTTCAAGCACATTTTGCAGTTTGCTACAAATTCTGTTGTACATAATGCAGACGCACACT
CAGGAGGCCAATTTAACTGTTAACAGTGCATGGAGCGAATGCAGCATTTTAAAAGATCTAGGTTTTTTTAGGTCATTAATGTGTCCTTGG
TTGATCAGTCATCTGGTCCCTCCTACTGTGTGTTATGACCACCACGTAATCCATTCTCGCTCTTTCTGATTTGGGGTTTTTCCTCATCCA
TCCCATTAGTAGGGATGTTTTCTGTGTTTTCTAGCAAGAAAAAAAAATCAATCAATCAAACCTGCATACATGTTACTCATGACTGTCATC
TAGTCCTAAATCTCTTCTGTTGTTGAATCATCCTTGCAAAACAGCTGAATACATCTGGAGAAAACACAGCACACCAAAGAAGCAGAATAC
TGCAAACCAAAGACATTTATGACTTGTCATTTTCTAGCCTAAAAATACTGTGATTACTTTTAGAAATCAGAAAACCTCTGCAACTCCGAA
TGGCATTCAGCTCTTGCATTTGGCGCATCATCGGGCTGAGCGGACCAGCTACACCAAGGACATTAGCCAAGCCACCCAGAGGGGTGGCTT
TGCCACACCAGTTGTCACCTTCCCATAGCAAGTGGAAGAGCGCCCACAGAACTCTGGGAGATTGCAAAGGTCACAATGTGCATATTTACC
AGTGAATGGCCCCGGGTGGGGCCACGTGGGGGTGTTCAAAGCAAGCCAAACGCTGCAATCATTCTTTACAGACACTTGAGACTGACTTTT
TTATGAATTACTTAGTCGAAACCAAAGAAACTTTTTCTGCACCTACTTCTGCAACAAACAAAACTGTCCCATTAAAATGAATAAATAAAT
CCGTAAATCAATGGAAATCACCACCAATAAGAAGGAAGCACGCCAGAAAATAAACGAAAACAAAAACAGGGAGACACACTGTGTTCAAAC
AGACCTCTTGGGACATTTTTTGGAAGCAGATTTTAAAGAAAGGGTTGAGACAAAGATAGAAATAAGGAAGAGCCTCAGTGGCTGCTGCTT
CATTTGACAACTCACACGGTAATCTTAAAGCTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACACGGAACAGAGCAA
CAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTTCTCACACCTTTTGTTTCAGTTCATTATCTCCTCTTGCCTGGCTAAAATACT
AATAGCGCCATTGAACTGTATAAAGGTAATCAATTATGTTTCTCTGAGCAACAAAAGGAAAGGGCCATTTATTTGATTTTATTGTTTCAT
TTCAATTTTGTCTTATGGTTTTTTGCCCCAACATGGAATCTCTCAAAAGTTTCCATGGACTCCAAGTTTAAGATGTTGGGATATTGAACA
GTTCTCTCTGCTCAGCAGAGGGTAGGGAATAACATTATCACTTGAATGTTCTTTGCTTAACCCTTAGACTTGGTTCCTTCTATGTTCAGA
GTCTCATCATCAGGGGAAGGAAAGGGAGTGAGGGTCAGGGATAGGGGTCTTGGTGATGCATCCTCTCCCGAGCCACAGAACCAAAGAGTT
TATAGAGGAATTTACAGCCTCGTTTTCATGTGATTGCTACATCCTAACAGGGCTTCATTTGGGGGTGGGGGGAAACATGTAAAAATAATT
GCCAGTTTCTACTTTTCTATTAGCTTTTTAAAAATCAGCTGTAAAGTTGCATTTCTAAAGAAAGATATATATAATATATAAAATACATAT
ATAGATCAACTTGACATTGGTGATAACCAAAATTATTGCTGTCCAAATTCATGTCTTGTTTTGGTCCAGTGCTTCATTTGCTAAGTATTC
GGTTCAGAATTTTTCTCATTTCTCATGCCATTCCAGAGTTAATTTGCCACTGTGGATGATTTGAAGTATTCAGATCTCTATGGAAGTTTC
TGGGACAGGTTTAAAGTCAAGATCAAGCATTTTAGCATTTAACCTGTTGATAAATGGATCCATGGTGTACATGAGTTTTATTTGTATTCG
GAGTCATCTCTATTCTATCCCTCAGCCTCGATTAAGGTGGTGAGTGAAGTGCATCCAACAGACTCGGCCCAGAACTGGGTCCTGACAGTG
GGGTGCTCATCTTCTGTAACTGTTGGGAAGGCTCGGTGGTCCATTTTCACCAGTTAAAGAATATGAGGCCAGCCCAGAAATCTGTTCTCC
AGGAGCTGCCCTGTCCCATCTGGGTGTGCCAGACCCCCTCAGTGAGCAGGTCCACCAAAGGGACTTCTCACAGGGGAAGCCCAACTCCTG
TTGCAATGGGTTGATAGATTTCCTCAGGGTGGTAATTACCAATTCGTATTTTGACAAGCCTATGTGCAACCACAGCTGGCACTGGGGTGG
GCAGTGGTGTTGGGTGGGATGGGGGAGAGTGTCTCAATCCTGAAGAGAAAATATAAAGCAGGTTTTGGGGAGACTTCTGGAGTCCTGCCC
CTAGAGAGCCCCATTGTTGTTCTTTGTGCCCCCTCCTCATTCCCCCTATGTGGGTCTCCCTATGCAGGAGCTGTGAGAGAATGTGACTCT
CCACAATTTTTATAATTCATCCTTCCTAGGAGATTGTTCATTGGCTCTTCCCTTGTGTCCCTTTGTCCCTTGCTCATACTCCATGTTTCC
TTTGTCAAAGGACTAAGAAAAGAGCATATTTCAGCAGAGGAGTGTTCCCATGTGGGTTGATTTCAACTTGGGTATTTCTAAAAGAGTCCT
TGTGACATGTGTCCAGTGGAAATGGTTGCTCTTTTCCAGACTGGATTGAGGAATGGAGCCTGTTTGATTTGGTTAGTGATTCTTTGACAT
ACTAATCTCAGCGTTTGGGTCTCCAGCATCCTCTGAAGATGTCTAGACTAGTAGAGGCTGCCTTTGTGACCTGACATTACAACATTGGTC
AAACCAGTCCTCTGATAATCAGAAGAACATGTCATAATTGTTTAAAAAAAAAAAAAAGGCAAGAATTTCTCTCCAAGGAGCTTTAATAAA
TGTCTCATTCCAGATAATGTCATACCAGAGAAAAGTGCTTGCTTTTAGAAAATTATTTACATACATATATAAATATATATGTGTATCTAT
ACAGTTATGTATCAAAATTTTAAGCCCTGCAGAATTTCAATTTGTTAGAAATCTAACAGAAAAAAATTTCTATATTGAAAGGTAATAGAA
TTTAACCCAGTGAGTTTACTCAAGGATTTTTAAATTTAAGTTAATAATTTCAGAGAAAATAACCATTTGGGTGTGGTTATAGTTTAGTAT
CCATTACCTCAATCCAAGGAAAATTCCAGGCATTCCTCAACCATCAGGAAAAGGTACAGTGTGAAGGAACAGTTCTCAGCCAAATTTCAC
ATTCTTGAGGCAACAGAAATCAAAACACTCAGAGCCATTGAGTGGAAAAACAATTTACTTTATTCCTTTACACAAATAGGCTTGCATTGT
TTTTGTTTTAATGTGATTTTGGTACTAGGGATATAATTATTTCATTCCAGGAAATAATAAAAAAAAACAGACAGAGCCAATACATTTCTT
TTTTTAAAGGAAACAGCAACAACAATAAAAACTCAGCACCAATATTTAAAAGCTTTTCCAAAATGTAAAAGAAGTGTTTAGCTTGCACCA
TGCATAAAGGTGCAGGCTAGTTGAACCAGGAAGCATGGCACTTCCTCTGGAGAAATCCAGAAAGAGTTGCTTCTAAGCTCCCTTTTCCCC
CTGCAGGCTCTTGGCAATTGTAGGCTTTAGCAAATCCAGAATAATTTTCAATTCAAGCTAAAATAAAATCAACATTTGGAATGTAAATCT
GATACACACACACTTTTCTAAGTCAAACAACATATTTCAAAACCAAAAATAAATACCTTTTAGATAATCAGTTATTTTCTTTGTCTATAC
TGGGCACCCACCTACTAGTGCCAGTAAATTCAAGTTGAACAGATTTTTAAAATCACTATTATCTGGGTATGGGGGAAACTTCCCCACTTT
TGAAAATGTTGGTAGAATTATAGGAATGTCTGTTTGATTATCATTACCAAAGTGTCATGACAGTATGCCTTTGTAGTGAACTCGGATTTT
CAGGAGTTTGAATAGTTGGATATTTTAAAATCTAAGAAGAAAAGGCCTGTTTCCAATGTTGTTGAAGAATAATGAACTCTATTAAAAAGT
GGAGAAAAAGATAATACATGTGGTCAAGGTTGACCACAAGGCCCAGGCACAACTACCTTGGCGATAATCTTCTAGATTCGTAACAGGTTA
GAGCTGACTTTTTGTTTTTGTTGTTGCTGATGCTGTGTGATTCAGACTTCTCAGCCTAACCAGGAAGAGTAAGTGGAAATGGTAGATGAA
GAAGGGGTAGAGCTGGTGTATCTATAACTTTCTGATATTTGTCTGCCAAACTTGATATATTAGTAATTTTTTTATCTTTAGCTAAGATCA
AGTCACCCCTGAAACAACAGGAGATTCTAGTTTTAAAATAAGGCCACAAAAATCCTTACGGAATGAAGAATGGCACCCCAGTTGGTTGTA
TAAGTCTCATAAGATAATGATGTTGATTTTAAATATGGATGTCTCAATGCCTGTTTTCTATCAATGATTTGTTTGTTTCCAAGGTCGGGG
AGGGAAAGAGGGGAGGGTTTATCTGTTTTAGAAAGTCTCAGAATACTTATAAAATACAGAAGTAGTTATTAAAATATATAGGACCTCACA
TAGGTAGATACAGAACTTACCATTGAGGCTGATGGGCTGTTGTGTGAATCACACAGGACCTTAAATGAGGCTCATTATTCTCACACACCA
AAATGACTCTGACAGCCTGAAGCAGTTATTGCTAGAGCCCAAGCTTTCCTTGGAGGTTTTGGAGTTAGGTTGATTGGAAGTAACCAGCTA
ATACCTTTTCTAGTGGAGAAAAAGACATTGCTACCAGCTTGTTCATCCCATAGAAGTCTTCCACTCTGCTCCATTTTTAGCAGCAAGCAT
TTCATGTAGCATAAACCTTGGCAGATAAGTGTGCCTAAGGTTTATACAGTCTGTCCGCTTGGATGTATACAAATTTAGATACATATTTTA
ACATGTGTTCTCATAGATGACTTTATAACAACACACATTACCTATAGGTGTCTAGACTGTGTACATACAAGTGTGTACAGACAAGCTTCA
TACGTATATACTGTAATCCGTTACAACAAATAAATTTTAAATCATCGTTTAACATGTATGTGGTACTTCTACAGTGTACATTGTTTTCAT
TATTTATTGTAACATTGAAAACCACAGTGCAGGGAAAACAAAAGTATCCCAGCATCTTCATCCTGTACACTTGGAATTAATTTCATTTGG
GCATATCCAAGATAAACTCAACTTTCAAGAAATCTTGTATATTATTTAATCATCTGTGTTAGGATGACACCTATGATTGATGACTTCGGT
TGAATAGCTTTATTCTGGATTTTTCATAACTAAAGCTAAATCCAAAGACCTGAAAAAGGACAAAAAGAAAAAAAAAAAAAGAAAAAACAA
AGAAAAAGAAGAAAAAATAATAAAGTCAAGCGCAAACTGATGGGGAGACAGTGGGCTCTGGTTTCCAGGATTGAGACAATGGTACTGCGG
TCTTGGGGAGACTGCGTTAGCTAGTGGGGAGTGGTGATTTTTTTCATGCTTGTCACATCTAAATGGTCTTTAACATGAGAAAGTTTTAGA
GGTTATAATTTCCTGCTTTGTTTTTATTTAGACTATCAAATGAAGTTATACATGTTGTCAGTCAAAAAATGAAGACACCCTCTGCCCCAC
CCCACAGAATGCTTTTTATCTTGTCTCTTTGGGTTATGACCCAACAAGCTAAGTACCATTAATGTAATTAACTTATTTAAATTAGTTCCT
AGTACATAAATGTATAGGATTTGGGTAATTATTTAATCATCCTTCCTTAGTTTGATTCTACTCCTTGTACTTATTTATCAAAACCTAGAC
CAATGGTGCATCAGAGATGCAAAATTCTACTTGGAATACTCTTGAAGTTTAGTTTGCTTTATAAAGCAGTGAAATTCTGTTACAGACAGG
GAAGAAATACAGGTTACAAAAAGAGAATTTGGGATATTCTTCCCTCTTAAATTAACTTTTAAAATAGTCTAAGTAACAATTTTTAAATTA
TTTAACTTAAGTTCGCAGCCCCACCTGGTACCAGGCGAACTTCACCTCTTAATTATTGTGGCCCTCGGAGCCTTCATATTGTAACTTATT
TATTTAACTTATTCAGCATCTGTGAAAGGTGCACTGTATAGTTTATATTTTTAATTTAAAACAACAGAGAGCACTGCAGTTTGTTTGCTG
TCAGAACAACAGAGCAAATTTTGTGGACAAGCAATGACTATTCAGCCTGAACCTGTGCATTCAGAAAACATAAGCTGAGACCCTGCTTCA
CCAGCCTGGATTTCGGGGCTTCTATACAGAAACTGGAAAAATAAATTTTAAAAAAATCGTAAACAAAAAGAGAGAAACCCTTACACTAGC
TGCTTCCAAGAATGAACTCTGTGTGTATGTAAAGCAACAAAACAAAAAAGGAAAAAAACAAAAAGCAGAAAAAAGAAAAAAAAAATGAAA
AACTTTCTATTTCTAGTGAGAACCAAAGAAGGCTACCTCACTGACTTTTTCCATTTGTAATTTTAATCGTGTTGATGACACCAAAGATAC
CAAAGATTTCTTTCTCTGTGCGGTCTGCATTTTGCTTGTGCTCTTTTATAATTTGAACGATTTTCTCTGACATATGGTATGTACAGCCAC
AGCTCAGATACCCCAAAGAAATAATTATCTATGCGACGGCGGCTGCTAATTTGGAAAGGGATATTTTCTGTGTTTCTCTTATATGTTTGC
TGTCTGCTCGACATGTTCAAGATGCGAGTTCAGATGCTGCTGTAATTGGATTCCTTAAATTCTGATTACAAATTGAGGAAGGAAACTGGT
TGGAAATGGCCTTCAGTCCTAGCCATGGCCTCTATCCCCGCTGGGACCTGTCACAGTAAAGACTGCCAATTACTGAACCACAGAAGCTCT
GACCATTGAGTAGTTGAGCTGGAAGAGACCTTAGGAATCATTTAGTCCAAGCCCCGGTGGCCCAGAGGAATGAAATAGTTATCCAAATCA
AATAACTCTTGAGAGTGAAAGCCCACACATGCCTCCTGGTTCCTGCCCCAGTGCTCCGCTTATTGTACAGTGCTACCTCTGCATGAGAGC
GGTCCCACATTGACAAATAGGATGGTGGCAATCCTTTAGCAATGAGCAGGGACTGGGGTTTATCTCTTAACATTTTCAGCTGTAAAATTA
GTCACAAGCATTTTCAGTGTCCCATTAGTACATAGTCACATATGGTCGGTTGCTTCGTGAAGGTGGCCTGTCTTGAAATACTAGGGCTCA
TACGGGATTTTTGCCCTAGGAAAAACATGTTGATCCCAATGATGTGATCACTTTTGAACCTTTCCATTACAAAGCATTGTATAGATAACT
TTTTAATTCAGTAGGAGGAGAAAGTTCATTCTTGGCCTGTTGGCTTTGATTATTATGGGTACTTTAAAGTCAGTATTTATCAAGAAAGGG
AACTTGACCACCATTGGCACATGTGACATTTAAGCTCTTCAGCCTTTTCCTTTTTAGTTGTAGGTGTTTACATTTCATTTCTAAGCCAAC
TCTGTATTTATGAGAGAAGTTTAAGCCTTACATCATTTGATACTAAAGGGTTATTTGTGGTAAATGAAAAATGACCCCAAAATTACAGAG
GAATATGCCAGTTTAAGAAATGGCTACTTAAAGTTGCTTCTCTCTTTCCTTCTTACTCATGAAATTAATTGGTCTTCTTCAAGTTTCTTT
AGATTCCATTAAATGATTAAATCACTATTAAGAGCCATTCATCAACGTGATTTGTGTGTTAGCCAATGAATCTGTCTCAGCTTTTGACCA
AATGGGTTTTAGACAAATGCAAAGATCTGCCTCTAGTCCATATGGCTCTTTTTGAGTGCTAGTATTTTGCATTTCACATAATGTAGTTAT
TTTGAGCTTTTAAAGAGAGCATTTAGACAAAGAAGCAAAGAGAGGAAGGGACCAATCAACTCATCAGTTCCATGCATCAACAAAGCATAG
CTAGTAGAGGAATATAAATGACAGATTGACAAACTGTAGGAAACACTGTTACTCTCTTTCTGAAGTTTTCAAGCACCATCCTATGTGAAA
GTTCCCTCCTGTCCAAACAAGCTCAAGGCCCATCTTCTCCCTATACAAGGCAAACCTGTAAGGCCTTCCTTCCAAAGAGTACATTGCTTT
GGTTTTCTTCCTAAATTCCTATTGGAATTAGAACTCTCAGAATCCCTGGGAGACAGAGCAAAGATGACTTAATTCATTGAGCAGCAGAGC
TCCCTATAAGTGAACATCACCTTCCCCATCTTTCCTACTGCCACACCCATACGAGAGAGGATCTAGAAAGAGCGATGGCAGCCTGAACAC
AGAAAACATCCCCACTTGGCAGACCTCTCCTCAGCAATCCCCCCAGCCTCATGCTTCACTTGCAAAGTGTGACATAACCACGGGACGAGT
GCCTTGCTTGAACCAAAGCAACGATTTAGCCAGTCTGGACCTCTCTGTGCTTTTTTTAATTCTTCCTGTGAATACCTCAGCTTCAACTGG
GCCTCCATACAGTCAGTTGGTGGGCTTATTGTACTGTGGTGCTTTGCAATGCAACCCTGCAAAGAACAAGATTTGTACTAATACCAAAGG
TTCTTTCTCTATGTCTCCTCCTCTGCCTCCCTCGTTCTTCCCTTTTTTCTAGTTCTTCACGGTTCCAAAGCTTTACTATGAACCTGGGCA
TGTTGGCAATGCAGACCGCGCAATTCCTTACCGAATTTTCTCAGATATACCTCATAGACAATAGTGTTTAGAGTAATGTTATTATAGCGT
ATGTAATAAATTATTCACTGTTTCTTTTGGTAACTGTGATTTAAAAAAAGAAAAAAGAAAAAAAAGCTTTATACGTTTTAGGTTGTGCTT
TTGTAATAGATGAAAAAAGGTGCGCTTAAAAAGAAAATGTATGTTTTTTTCCCCCTTTGGATTTTATTTATGCTGGATTGGGGAAAGTTG
CAGAATGAGCCCAAAGTTTACAGTTTCATATTTTGCTGAAGAAACAATCTGTGTTCATTTGCTCTGTTGAAAAGAATAATTATTTTCTAC
ATTTGTGCCACTTGGTCTGAACAATTAATTGTTCCGTGTTAACAGTGTAGTATTATGATTAGCAACTGCCAATCAGTGCTATAATTTTAT
GCATGAGGCTAAAAATTTAGCAGTGTGATGCATTGTGGTCTTAATAGCAACATTTTTCATTTTGAACTAGATCTTCCCCTTTGGTTCAAT
GGACTTTATTTATGCATGGGCGCCTATTGTTTGTTAGCAGTTGTGGAACAGTTGTGTATACATTAAACTGTGAAAATGTACACAGTTCAG
CCTCAGACGGTGGTAATATTGGTTTTATTGGGAGATGTGTCACCTCGAAAATACCCTTTACATCTGTTGGGATCTGAAAATGAGTCACAT
TGAATTGGGTTCCAGCTTTATAATGAGAAACGTTATTCCTAATTTTTGAGTTAGCCAATTTGCATTCCACAAATTGGGATCCTCATAACC
CAAATATATCACCGTATGTGAGAGGGATTTGAAAGCGAGTATTGAAAAACTCACCTTTGCATATTTAATTTCCACCAAAAGGAGTTATTT
TGGCTTTATGCTCATGAACTTAGACCTAACTGGCCATGTATATGTAGATGCAAATTCATCTAGCTGTGGCCCTCTTTGATCTCTGCTTGG
GAATGGCTATTTTTGACTATGCGTGGTTTCTTCTCGTATTTTGTGATCAGGTCAGCTCCCAGTAGAAACTCAAATGGCATCAATATTACT
AACTCTTCTCTGCCCACTTCTCTTTTGTCCACTCTCCTAGACATTCCCACCAACTGTTCCAGTGATTTGGGCAAAAATACGCAGCCATTT
CCCAAAACTTCACATGTGCAGCTATCATGGCTGTCCCTCCCTAGACTTGGAGGTGACTCTCACTTAATTTTTACCTGCCCAACAATGTTC
CATCTACCATCTAAAAGGTAATATAAGAAGAAGTTTTGAAACCCACTTTAGGAAAACCATCTTCTTTAAATCCTTCAATTATCTGAGGCC
TCTATATGTCAAAACTATTTTTCAGTTGCAGGGGATTGGGCAAACTTGTTCTTTCTTATACTTGGGTTCAAAGACCCATTCTCCAGTTTC
ATATTTCCCAAACCAAAATGCTTGACATAAAGCCAAATCAACTGCCAAGCACACTTTATTTTGCATAGGAGTATGCAGCCTAGGGAACCT
TGGTTGAAAAGCAGCAGTCTGCTATGCAAAATATTGGAAATCACTGACAGTGTAGCATTCATATTATCTGTCAATGAGGGTATATTGGGA
ACGTGCTCTCGTGAATAATAAAAAGCAACATATTTTTATTTGGCCTTATAAATTAGGTTGTGGTAATGTAAACTTTGATATATAGTCTTT
TTATTTTTCTCTTATTAATCTGCCAAAGATGGGAACAGATACAAGAATTTTTCAAATTGGCTTTTGTAAGACAATTGATGATTGTAATAG
TGTTTAATCTTCCAGAAAGCTTTATATGTTGTTCCACAATAAAATTGATATTTGTTTCAGCAAAGTTTTCCTGACACTCACAAACCCACA
AACTGTTCCTCTTAATGCAGATATTGTAGAATCTACAAAGTTCAAATCCATTTTTGATCCAAAGAAAGTAGAGGAGTATTTGAGACATGA
GTGTACCCAGCCCTTTTTTTAATCACAGGCAATGCATGGGTCTGGCTGGTTACACTTTGCCAAGAAGACTTGTCTTATGAAACCCAAGGT
ATATTTTGTTATGCCATTTTATGTCCTTTTCTTTTAACATTGTGGAAAGTGGTATGTTGAATCAAGTGTAAGCTGAGTTTTCCAGACAAC
TGAAGTAGCTACATCATGAATGTTATTTTGTTATTAAAGGGTTTTTACTCAGTGCTTTGTGCCAATGGATGTCCTTTTCCTTGGAGACAC
ATAACTACAAAATTACCTCAGCTTGGCCTGGTTTTCTCTCCTGCCCTCTTGGGGAAACATGGGCCTGGCCTGGGAAAAGGCAGGTCATGG
GCTGGAAGGTAGGTTTTGGTACTAGGAAGAAATCTCTGTATCTGTCAGCTTTAAAGAGAACTGGGCCAAAAATCTCTAACCTCACTCTCT
CTGGACTCCAACACTTCCCTGCAATCCTTTGGTCTTGAGCATGTGCCAGCATGAAGGCAGACTCCAGTTCATACATGAAAGGCAAGAAAA
AGAAAATAGTAACCTTGAATCTTCTGTGGGCCACCAGGCACTCACCTTTCCCCACCTTGCACACTATCCAGTCAAGGCTATTGCAGCCCA
TCTGGTGGCTTTACATGGGACATTACCAAAGGCTTCTTCCTCCATCCTGGGGTTGCAAAGGATCCAGGTCCCCTCCATCCAGTGGGGCTC
TTCCACATCAGAAGTCCCCCTCCCACCATCCTCTGCATCCTGTTTAGCTATCCCATCTATACCTTTTGGAGATGATTATTTAGAAAACAA
AGAAAGGTATGGAATGGGGTTTCCTATTGTTTGCTAGGTTATATTTTAGCAATTCTCAATTCTTTGATCTGGAAAAATACAAGAGGGAAA
AGGAGACCCCACTATCTCCCTGTGCTTTGCTCCCATCTCAGGGGGCAGGGGCAGTGCACATTGCCTATGCTGTTGATCTGTCTTGGGCGA
CAGGCTGAATCACAGCTATTGCCCCAGCCAAAAACATGGCCCATCAATGCCTACTTTATCTCTGCTTGAAAATCCTATTCAAAAAGTTGT
AGAGTTTGAGGTTTTTATCCCCCCATATCCTTTGCTTTGGTCCAGTTTGGCCTTTAGCATAAGAGTCAGCTTTATCTCTAGGAAAGTTTT
TTCAGATTATGACAAGGAACCTGCCACCTGGGAAGAAAAGAGTCCGAAGACTAGCAATCGGATAGGTAGTCATACCATTAACAGATACTT
CCTTGAAGGTAGAATATTATTTCCTTTCTTTACAGTTTTGTGTTACACAAGTCCAAGTGGTGCCAGCAAACTTCTTACCGTGAAATGTTG
TAAAACACCTGGCATACTGAAATTTCTGAAACAAAAACACAAGCTCCACATTGATAACTTGATAAATAACCACTAAAGTTTAGATGCAGG
GACTGAGATGATACAGGCAAAATCTTGGTGTTGGTTTCTCTTTTAATTCGTATCTTCGATCACCTAACCTTTCTCAATCCAAGAGCAGTT
CAGTCTTTTCTCCCCAAGTCTAGGATGCCAAAGAGCATCATAGGAAAAGATAATTAGGGATTGACCAGCATTTCAATTAGTTCTCTTCTT
CATCTTTGCATTTCTCAAAAGTGTTCTCCTGGACCAGAGGGAAAGAGCTGGTCCATTTTTTTTCATTCTTTCTATTCAAATTTTTCCACC
CAGACAATACTTTATTAACACAGATACTGTAGATCCTTCCTTGGTCAGTGAATTATTACAAGAGGAGCTATCCTTCCACCAAAGTGAGTG
AAAACAAGTTCCAGTATCTTTTCTTCCATCCAGTTTTGTTCTCAGAATCCAAGTCAGTCCTGGGTCTTTTCTCACTTTAGACCCTGGCCT
CAGATGTGTTTATTCTTGCTATTTAAAAATACCTTTAAATTTCACATGCTGGCCTGCAGAACTTGCATCCTTTGTTCTATACTGTTGACT
GCTTGATGGTATTGAAAGGTGACTATAATGAGGGAAGAAAGGAGGAGGTAAAGAGAGAAGAATTTGTCCCAGATCTGTTTAAAGTTTCAA
AATTTAAAAAGGGACCCATTAAATTATGGGAAAATGGCTATAGAGTGTGAGCCTCCGTTGACCATATGCTCAAAGACCGTACTCTGCCAC
CTGCCTTCCAGGTAGCTATTCTAGAAACTCAGTCCTTTGTGGAAACCCAACTACCTTTTAAAAGTCTCTTTCCAGATTCCAAAAGGACAA
GAGATCAGAGAGTCACATATACGCCTCTTGTTTTATTTTCTTGCTTTCACGGGTATTATTGCCAAGAAAATCGTAGGGAAAAACTTTAAA
CTTTTCTTTTCAGTTGATCCCTTTGACATCACCTCTCATGTTTAAAATCAGGAAAACACACCCCTAAAATTTGCACTCTCTTCCGTTTTG
AAAAAGAAAACCCACACACAAATGCACACTATTACCGTCTTTCACCCTGCGCTATATTTCCAAAGTGTATTATAATCCAGATATTGCCCC
ATCTCAAACATGTTAAGTCAGACTGTGCTGAAAGACTTTCCAGGGACGGTCAACAGGGTATATGTTCAGTGGCTGCCCTGAAATCCTGGT
GGGGATGAGGATCACGCTTCATCATCAAGGGGATGCCCATCCCCTGATAAGCTCCCAGTCCTTTTGGAAGATTTCTTTGAATGTTAATTG
CATTTTCAGTTTTGCTCATTTCCCACCCCAATGTTTTGTCTGCAACATCGCTTACACTGGATTCTTTCTATTTTTATTCCTATCATTAAA

>18676_18676_7_COPZ1-ONECUT2_COPZ1_chr12_54718965_ENST00000553231_ONECUT2_chr18_55143669_ENST00000491143_length(amino acids)=147AA_BP=
MGDRLNHSYCPSQKHGPSMPTLSLLENPIQKVVEFEVFIPPYPLLWSSLAFSIRVSFISRKVFSDYDKEPATWEEKSPKTSNRIGSHTIN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for COPZ1-ONECUT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for COPZ1-ONECUT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for COPZ1-ONECUT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource