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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:COQ10A-USP5 (FusionGDB2 ID:18682) |
Fusion Gene Summary for COQ10A-USP5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: COQ10A-USP5 | Fusion gene ID: 18682 | Hgene | Tgene | Gene symbol | COQ10A | USP5 | Gene ID | 93058 | 8078 |
| Gene name | coenzyme Q10A | ubiquitin specific peptidase 5 | |
| Synonyms | - | ISOT | |
| Cytomap | 12q13.3 | 12p13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | coenzyme Q-binding protein COQ10 homolog A, mitochondrialcoenzyme Q10 homolog A | ubiquitin carboxyl-terminal hydrolase 5deubiquitinating enzyme 5isopeptidase Ttesticular tissue protein Li 218ubiquitin isopeptidase Tubiquitin specific protease 5 (isopeptidase T)ubiquitin thioesterase 5ubiquitin thiolesterase 5ubiquitin-specific | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q96MF6 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000308197, ENST00000433805, ENST00000546544, | ENST00000541969, ENST00000229268, ENST00000389231, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 5 X 6 X 4=120 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/4*10)=2.90689059560852 | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: COQ10A [Title/Abstract] AND USP5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | COQ10A(56663345)-USP5(6964565), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | USP5 | GO:0016579 | protein deubiquitination | 24424410 |
| Fusion gene breakpoints across COQ10A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across USP5 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-06-0129-01A | COQ10A | chr12 | 56663345 | - | USP5 | chr12 | 6964565 | + |
| ChimerDB4 | GBM | TCGA-06-0129-01A | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| ChimerDB4 | GBM | TCGA-06-0129 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
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Fusion Gene ORF analysis for COQ10A-USP5 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000308197 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| 5CDS-intron | ENST00000308197 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| 5CDS-intron | ENST00000433805 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| 5CDS-intron | ENST00000433805 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| 5CDS-intron | ENST00000546544 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| 5CDS-intron | ENST00000546544 | ENST00000541969 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000308197 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000308197 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000308197 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000308197 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000433805 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000433805 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000433805 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000433805 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000546544 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000546544 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| In-frame | ENST00000546544 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + |
| In-frame | ENST00000546544 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000308197 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964564 | + | 3855 | 837 | 105 | 3302 | 1065 |
| ENST00000308197 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964564 | + | 3777 | 837 | 105 | 3233 | 1042 |
| ENST00000433805 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964564 | + | 3611 | 593 | 8 | 3058 | 1016 |
| ENST00000433805 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964564 | + | 3533 | 593 | 8 | 2989 | 993 |
| ENST00000546544 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964564 | + | 3572 | 554 | 5 | 3019 | 1004 |
| ENST00000546544 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964564 | + | 3494 | 554 | 5 | 2950 | 981 |
| ENST00000308197 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964565 | + | 3855 | 837 | 105 | 3302 | 1065 |
| ENST00000308197 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964565 | + | 3777 | 837 | 105 | 3233 | 1042 |
| ENST00000433805 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964565 | + | 3611 | 593 | 8 | 3058 | 1016 |
| ENST00000433805 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964565 | + | 3533 | 593 | 8 | 2989 | 993 |
| ENST00000546544 | COQ10A | chr12 | 56663345 | + | ENST00000229268 | USP5 | chr12 | 6964565 | + | 3572 | 554 | 5 | 3019 | 1004 |
| ENST00000546544 | COQ10A | chr12 | 56663345 | + | ENST00000389231 | USP5 | chr12 | 6964565 | + | 3494 | 554 | 5 | 2950 | 981 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000308197 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.002428941 | 0.99757105 |
| ENST00000308197 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.001804844 | 0.9981951 |
| ENST00000433805 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.001494028 | 0.99850595 |
| ENST00000433805 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.001416571 | 0.99858344 |
| ENST00000546544 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.001629509 | 0.99837047 |
| ENST00000546544 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.001767996 | 0.99823207 |
| ENST00000308197 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.002428941 | 0.99757105 |
| ENST00000308197 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.001804844 | 0.9981951 |
| ENST00000433805 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.001494028 | 0.99850595 |
| ENST00000433805 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.001416571 | 0.99858344 |
| ENST00000546544 | ENST00000229268 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.001629509 | 0.99837047 |
| ENST00000546544 | ENST00000389231 | COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964565 | + | 0.001767996 | 0.99823207 |
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Fusion Genomic Features for COQ10A-USP5 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.009660038 | 0.99033993 |
| COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.009660038 | 0.99033993 |
| COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.009660038 | 0.99033993 |
| COQ10A | chr12 | 56663345 | + | USP5 | chr12 | 6964564 | + | 0.009660038 | 0.99033993 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for COQ10A-USP5 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56663345/chr12:6964565) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| COQ10A | . |
| FUNCTION: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (Probable). {ECO:0000305}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000229268 | 0 | 20 | 326_856 | 37 | 859.0 | Domain | Note=USP | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000229268 | 0 | 20 | 654_695 | 37 | 859.0 | Domain | UBA 1 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000229268 | 0 | 20 | 722_762 | 37 | 859.0 | Domain | UBA 2 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000389231 | 0 | 20 | 326_856 | 37 | 836.0 | Domain | Note=USP | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000389231 | 0 | 20 | 654_695 | 37 | 836.0 | Domain | UBA 1 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000389231 | 0 | 20 | 722_762 | 37 | 836.0 | Domain | UBA 2 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000229268 | 0 | 20 | 326_856 | 37 | 859.0 | Domain | Note=USP | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000229268 | 0 | 20 | 654_695 | 37 | 859.0 | Domain | UBA 1 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000229268 | 0 | 20 | 722_762 | 37 | 859.0 | Domain | UBA 2 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000389231 | 0 | 20 | 326_856 | 37 | 836.0 | Domain | Note=USP | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000389231 | 0 | 20 | 654_695 | 37 | 836.0 | Domain | UBA 1 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000389231 | 0 | 20 | 722_762 | 37 | 836.0 | Domain | UBA 2 | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000229268 | 0 | 20 | 221_224 | 37 | 859.0 | Region | Note=Substrate binding | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000389231 | 0 | 20 | 221_224 | 37 | 836.0 | Region | Note=Substrate binding | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000229268 | 0 | 20 | 221_224 | 37 | 859.0 | Region | Note=Substrate binding | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000389231 | 0 | 20 | 221_224 | 37 | 836.0 | Region | Note=Substrate binding | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000229268 | 0 | 20 | 197_269 | 37 | 859.0 | Zinc finger | UBP-type | |
| Tgene | USP5 | chr12:56663345 | chr12:6964564 | ENST00000389231 | 0 | 20 | 197_269 | 37 | 836.0 | Zinc finger | UBP-type | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000229268 | 0 | 20 | 197_269 | 37 | 859.0 | Zinc finger | UBP-type | |
| Tgene | USP5 | chr12:56663345 | chr12:6964565 | ENST00000389231 | 0 | 20 | 197_269 | 37 | 836.0 | Zinc finger | UBP-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for COQ10A-USP5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >18682_18682_1_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964564_ENST00000229268_length(transcript)=3855nt_BP=837nt CCTTCCTTCCTCTCCCAGGCCCGAGCCATGGCAACAGCGTGACGTGGGGGTACCGAGATCTGCGGGAGCAGCGGTCCCGGCTTCAGTTCT AGCCTACCCGGCAGCCTGGACGGGAGCAAGGCGAGAGGTGCTGCCGCCTCCCGTCGCCCCTGCGCTCAGAGGTCCCGAACCAGCCCAGCC GCTGCCTCTTGCCGCTCCGCCTTTGGAGTGAGGAGGGCGCAGCCCGCGTCAGAACTTAGAGGGCCAGGCAGGGTCGCGCGCATGGCCTGG GCGGGCTCGCGGCGGGTCCCAGCTGGGACGCGCGCGGCAGCCGAGCGCTGCTGCCGGCTCTCGCTCAGCCCGGGCGCGCAACCGGCCCCG CCCCCAGGCCCTCTGCCACCGCCGCGACCAATGAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCT GAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATG GGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTA TCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAA CCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTAT CCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTG GAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACT GGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAG GATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACC AGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAG CATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTG TGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGA GAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTG GACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATA GACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATC CGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTG GAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAG TATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAG GCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAG AGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAG TACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAG AAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCC CCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTAC CTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGAC ATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAA GGTAGCCTTGGTTTCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTCCGACATCGCCCATGCTGGATGAATCA GTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCC ATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCA GCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACG AACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGC TCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGT CACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGT GCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAG GGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGG CAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACG GGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCC CAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTC CCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTT >18682_18682_1_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964564_ENST00000229268_length(amino acids)=1065AA_BP=244 MDGSKARGAAASRRPCAQRSRTSPAAASCRSAFGVRRAQPASELRGPGRVARMAWAGSRRVPAGTRAAAERCCRLSLSPGAQPAPPPGPL PPPRPMRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKG HLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFN KTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEA LLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYP LAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGN SCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGK GHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAE EEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLR GTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVM SHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADS -------------------------------------------------------------- >18682_18682_2_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964564_ENST00000389231_length(transcript)=3777nt_BP=837nt CCTTCCTTCCTCTCCCAGGCCCGAGCCATGGCAACAGCGTGACGTGGGGGTACCGAGATCTGCGGGAGCAGCGGTCCCGGCTTCAGTTCT AGCCTACCCGGCAGCCTGGACGGGAGCAAGGCGAGAGGTGCTGCCGCCTCCCGTCGCCCCTGCGCTCAGAGGTCCCGAACCAGCCCAGCC GCTGCCTCTTGCCGCTCCGCCTTTGGAGTGAGGAGGGCGCAGCCCGCGTCAGAACTTAGAGGGCCAGGCAGGGTCGCGCGCATGGCCTGG GCGGGCTCGCGGCGGGTCCCAGCTGGGACGCGCGCGGCAGCCGAGCGCTGCTGCCGGCTCTCGCTCAGCCCGGGCGCGCAACCGGCCCCG CCCCCAGGCCCTCTGCCACCGCCGCGACCAATGAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCT GAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATG GGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTA TCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAA CCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTAT CCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTG GAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACT GGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAG GATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACC AGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAG CATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTG TGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGA GAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTG GACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATA GACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATC CGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTG GAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAG TATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAG GCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAG AGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAG TACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAG AAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCC CCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTAC CTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGAC ATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAA GCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGC AACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGT GGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCC TTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCC ATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTAT CAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATC TACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCT GCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTAC CCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGG GGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCT GCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAG TGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGAC >18682_18682_2_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964564_ENST00000389231_length(amino acids)=1042AA_BP=244 MDGSKARGAAASRRPCAQRSRTSPAAASCRSAFGVRRAQPASELRGPGRVARMAWAGSRRVPAGTRAAAERCCRLSLSPGAQPAPPPGPL PPPRPMRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKG HLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFN KTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEA LLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYP LAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGN SCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGK GHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAE EEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLR GTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGST SAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAF -------------------------------------------------------------- >18682_18682_3_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964565_ENST00000229268_length(transcript)=3855nt_BP=837nt CCTTCCTTCCTCTCCCAGGCCCGAGCCATGGCAACAGCGTGACGTGGGGGTACCGAGATCTGCGGGAGCAGCGGTCCCGGCTTCAGTTCT AGCCTACCCGGCAGCCTGGACGGGAGCAAGGCGAGAGGTGCTGCCGCCTCCCGTCGCCCCTGCGCTCAGAGGTCCCGAACCAGCCCAGCC GCTGCCTCTTGCCGCTCCGCCTTTGGAGTGAGGAGGGCGCAGCCCGCGTCAGAACTTAGAGGGCCAGGCAGGGTCGCGCGCATGGCCTGG GCGGGCTCGCGGCGGGTCCCAGCTGGGACGCGCGCGGCAGCCGAGCGCTGCTGCCGGCTCTCGCTCAGCCCGGGCGCGCAACCGGCCCCG CCCCCAGGCCCTCTGCCACCGCCGCGACCAATGAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCT GAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATG GGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTA TCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAA CCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTAT CCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTG GAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACT GGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAG GATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACC AGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAG CATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTG TGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGA GAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTG GACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATA GACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATC CGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTG GAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAG TATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAG GCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAG AGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAG TACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAG AAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCC CCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTAC CTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGAC ATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAA GGTAGCCTTGGTTTCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTCCGACATCGCCCATGCTGGATGAATCA GTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCC ATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCA GCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACG AACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGC TCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGT CACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGT GCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAG GGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGG CAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACG GGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCC CAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTC CCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTT >18682_18682_3_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964565_ENST00000229268_length(amino acids)=1065AA_BP=244 MDGSKARGAAASRRPCAQRSRTSPAAASCRSAFGVRRAQPASELRGPGRVARMAWAGSRRVPAGTRAAAERCCRLSLSPGAQPAPPPGPL PPPRPMRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKG HLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFN KTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEA LLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYP LAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGN SCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGK GHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAE EEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLR GTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVM SHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADS -------------------------------------------------------------- >18682_18682_4_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964565_ENST00000389231_length(transcript)=3777nt_BP=837nt CCTTCCTTCCTCTCCCAGGCCCGAGCCATGGCAACAGCGTGACGTGGGGGTACCGAGATCTGCGGGAGCAGCGGTCCCGGCTTCAGTTCT AGCCTACCCGGCAGCCTGGACGGGAGCAAGGCGAGAGGTGCTGCCGCCTCCCGTCGCCCCTGCGCTCAGAGGTCCCGAACCAGCCCAGCC GCTGCCTCTTGCCGCTCCGCCTTTGGAGTGAGGAGGGCGCAGCCCGCGTCAGAACTTAGAGGGCCAGGCAGGGTCGCGCGCATGGCCTGG GCGGGCTCGCGGCGGGTCCCAGCTGGGACGCGCGCGGCAGCCGAGCGCTGCTGCCGGCTCTCGCTCAGCCCGGGCGCGCAACCGGCCCCG CCCCCAGGCCCTCTGCCACCGCCGCGACCAATGAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCT GAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATG GGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTA TCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAA CCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTAT CCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTG GAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACT GGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAG GATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACC AGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAG CATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTG TGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGA GAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTG GACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATA GACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATC CGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTG GAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAG TATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAG GCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAG AGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAG TACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAG AAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCC CCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTAC CTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGAC ATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAA GCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGC AACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGT GGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCC TTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCC ATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTAT CAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATC TACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCT GCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTAC CCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGG GGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCT GCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAG TGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGAC >18682_18682_4_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000308197_USP5_chr12_6964565_ENST00000389231_length(amino acids)=1042AA_BP=244 MDGSKARGAAASRRPCAQRSRTSPAAASCRSAFGVRRAQPASELRGPGRVARMAWAGSRRVPAGTRAAAERCCRLSLSPGAQPAPPPGPL PPPRPMRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKG HLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFN KTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEA LLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYP LAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGN SCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGK GHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAE EEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLR GTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGST SAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAF -------------------------------------------------------------- >18682_18682_5_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964564_ENST00000229268_length(transcript)=3611nt_BP=593nt GGGGGTCGCTGCGAACCCCGGGGTTCCGCGGTGGAGGGGTGCTATACTGGGATGCAGGCGCGGCGGGGACTGGCAGCAATCATGCCCTGG GAGCTAACGTAGAGCTTTGGATAATGCTTTTGCAAGTTGTACGAGAAGGGAAGTTCTCGGGGTTTCTGACCTCCTGCAGCCTCCTCTTGC CTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAA AGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGC CCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTT ACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGC GATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGT TTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGA AAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTA GCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGC CTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGG ATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCT CCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCA ACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACT CATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAG ACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCC TGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACT TCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGC TGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAG ATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCT TCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCA AGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAG AGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCA GCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCA CACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGT CCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCAC CCCTGGTCACTCCGGATGAGCCCAAAGGTAGCCTTGGTTTCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTC CGACATCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACA CGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCT CTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACC AGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAG CTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAA AGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGG TGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAG AGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTC TGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGAC TCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGT GCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCT CCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCC CCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGTCTCTTCCTTGTCCTTCTCTGGAAAATGCCAAAATACACGATGTGAATAAAA >18682_18682_5_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964564_ENST00000229268_length(amino acids)=1016AA_BP=195 MRTPGFRGGGVLYWDAGAAGTGSNHALGANVELWIMLLQVVREGKFSGFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAY SERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFS PGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEE KFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKC DMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKT MTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGH GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCL ATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRF ASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTS PMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQAL KALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIY -------------------------------------------------------------- >18682_18682_6_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964564_ENST00000389231_length(transcript)=3533nt_BP=593nt GGGGGTCGCTGCGAACCCCGGGGTTCCGCGGTGGAGGGGTGCTATACTGGGATGCAGGCGCGGCGGGGACTGGCAGCAATCATGCCCTGG GAGCTAACGTAGAGCTTTGGATAATGCTTTTGCAAGTTGTACGAGAAGGGAAGTTCTCGGGGTTTCTGACCTCCTGCAGCCTCCTCTTGC CTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAA AGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGC CCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTT ACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGC GATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGT TTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGA AAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTA GCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGC CTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGG ATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCT CCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCA ACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACT CATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAG ACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCC TGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACT TCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGC TGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAG ATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCT TCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCA AGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAG AGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCA GCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCA CACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGT CCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCAC CCCTGGTCACTCCGGATGAGCCCAAAGCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCT GCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAA ACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCT CCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACA TTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTA AAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACA TCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCT ACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGA TGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAG AGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCC CCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGG GTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGA TGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGTCTCTTCCTTGTCCTTCTCTGGAAAATGCCA >18682_18682_6_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964564_ENST00000389231_length(amino acids)=993AA_BP=195 MRTPGFRGGGVLYWDAGAAGTGSNHALGANVELWIMLLQVVREGKFSGFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAY SERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFS PGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEE KFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKC DMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKT MTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGH GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCL ATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRF ASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRK AVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDD LDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYIYFYQR -------------------------------------------------------------- >18682_18682_7_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964565_ENST00000229268_length(transcript)=3611nt_BP=593nt GGGGGTCGCTGCGAACCCCGGGGTTCCGCGGTGGAGGGGTGCTATACTGGGATGCAGGCGCGGCGGGGACTGGCAGCAATCATGCCCTGG GAGCTAACGTAGAGCTTTGGATAATGCTTTTGCAAGTTGTACGAGAAGGGAAGTTCTCGGGGTTTCTGACCTCCTGCAGCCTCCTCTTGC CTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAA AGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGC CCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTT ACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGC GATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGT TTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGA AAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTA GCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGC CTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGG ATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCT CCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCA ACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACT CATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAG ACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCC TGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACT TCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGC TGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAG ATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCT TCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCA AGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAG AGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCA GCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCA CACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGT CCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCAC CCCTGGTCACTCCGGATGAGCCCAAAGGTAGCCTTGGTTTCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTC CGACATCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACA CGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCT CTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACC AGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAG CTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAA AGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGG TGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAG AGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTC TGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGAC TCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGT GCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCT CCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCC CCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGTCTCTTCCTTGTCCTTCTCTGGAAAATGCCAAAATACACGATGTGAATAAAA >18682_18682_7_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964565_ENST00000229268_length(amino acids)=1016AA_BP=195 MRTPGFRGGGVLYWDAGAAGTGSNHALGANVELWIMLLQVVREGKFSGFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAY SERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFS PGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEE KFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKC DMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKT MTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGH GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCL ATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRF ASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTS PMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQAL KALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIY -------------------------------------------------------------- >18682_18682_8_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964565_ENST00000389231_length(transcript)=3533nt_BP=593nt GGGGGTCGCTGCGAACCCCGGGGTTCCGCGGTGGAGGGGTGCTATACTGGGATGCAGGCGCGGCGGGGACTGGCAGCAATCATGCCCTGG GAGCTAACGTAGAGCTTTGGATAATGCTTTTGCAAGTTGTACGAGAAGGGAAGTTCTCGGGGTTTCTGACCTCCTGCAGCCTCCTCTTGC CTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTACCTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAA AGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGCAGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGC CCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGGGTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTT ACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCAAGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGC GATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCACTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGT TTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCAATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGA AAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCCGGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTA GCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTGTCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGC CTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGGCCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGG ATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCCTCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCT CCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGACTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCA ACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACCCGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACT CATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGGCTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAG ACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGCGGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCC TGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTAACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACT TCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCCAGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGC TGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAGTACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAG ATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCAAGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCT TCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGAGCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCA AGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAGTTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAG AGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCGAAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCA GCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCGATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCA CACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGATCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGT CCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGAGGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCAC CCCTGGTCACTCCGGATGAGCCCAAAGCGCCCATGCTGGATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCT GCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAA ACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCT CCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACA TTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTA AAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACA TCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCT ACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGA TGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAG AGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCC CCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGG GTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGA TGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGTCTCTTCCTTGTCCTTCTCTGGAAAATGCCA >18682_18682_8_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000433805_USP5_chr12_6964565_ENST00000389231_length(amino acids)=993AA_BP=195 MRTPGFRGGGVLYWDAGAAGTGSNHALGANVELWIMLLQVVREGKFSGFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAY SERRIMGYSMQEMYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFS PGIPAYPRTCTVDFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEE KFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKC DMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKT MTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGH GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCL ATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRF ASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRK AVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDD LDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYIYFYQR -------------------------------------------------------------- >18682_18682_9_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964564_ENST00000229268_length(transcript)=3572nt_BP=554nt AAAGCTTGTTTGGACGACCTTCGTCTGGGATGCACTCTTCTTCTCCTTCACCTACAAATGATAGAGGATTACGAAGAACTATACGGTTGG CTCCTCTTTCCTTTGGCCTTAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTAC CTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGC AGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGG GTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCA AGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCA CTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCA ATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCC GGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTG TCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGG CCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCC TCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGA CTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACC CGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGG CTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGC GGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTA ACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCC AGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAG TACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCA AGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGA GCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAG TTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCG AAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCG ATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGA TCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGA GGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAAGGTAGCCTTGGTT TCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTCCGACATCGCCCATGCTGGATGAATCAGTCATCATCCAGC TGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCA TGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCC CTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAG AACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACT CCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCT CTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGC CGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGAC CACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAA GCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCC ACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTG TGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTG TTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGT >18682_18682_9_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964564_ENST00000229268_length(amino acids)=1004AA_BP=183 MFGRPSSGMHSSSPSPTNDRGLRRTIRLAPLSFGLRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQE MYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTV DFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVI LPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTD GSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRI GEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVP ESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIK KFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLV EMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLER AVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPP -------------------------------------------------------------- >18682_18682_10_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964564_ENST00000389231_length(transcript)=3494nt_BP=554nt AAAGCTTGTTTGGACGACCTTCGTCTGGGATGCACTCTTCTTCTCCTTCACCTACAAATGATAGAGGATTACGAAGAACTATACGGTTGG CTCCTCTTTCCTTTGGCCTTAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTAC CTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGC AGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGG GTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCA AGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCA CTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCA ATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCC GGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTG TCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGG CCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCC TCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGA CTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACC CGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGG CTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGC GGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTA ACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCC AGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAG TACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCA AGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGA GCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAG TTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCG AAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCG ATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGA TCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGA GGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAAGCGCCCATGCTGG ATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTG AGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCA CAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGC GGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAG AGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCT TCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGA AAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTA CCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTT GTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGA CGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTC GCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACC TGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCC >18682_18682_10_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964564_ENST00000389231_length(amino acids)=981AA_BP=183 MFGRPSSGMHSSSPSPTNDRGLRRTIRLAPLSFGLRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQE MYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTV DFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVI LPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTD GSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRI GEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVP ESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIK KFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEA AMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEG -------------------------------------------------------------- >18682_18682_11_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964565_ENST00000229268_length(transcript)=3572nt_BP=554nt AAAGCTTGTTTGGACGACCTTCGTCTGGGATGCACTCTTCTTCTCCTTCACCTACAAATGATAGAGGATTACGAAGAACTATACGGTTGG CTCCTCTTTCCTTTGGCCTTAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTAC CTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGC AGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGG GTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCA AGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCA CTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCA ATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCC GGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTG TCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGG CCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCC TCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGA CTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACC CGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGG CTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGC GGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTA ACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCC AGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAG TACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCA AGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGA GCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAG TTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCG AAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCG ATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGA TCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGA GGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAAGGTAGCCTTGGTT TCTATGGCAACGAAGACGAAGACTCCTTCTGCTCCCCTCACTTCTCCTCTCCGACATCGCCCATGCTGGATGAATCAGTCATCATCCAGC TGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTGAGGCCGCCATGAACTGGGTCA TGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCACAAGCGCAGCAGCCGACCCCC CTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGCGGGCCACGAACAATAGTTTAG AACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAGAGGGCCGCTCAGCTGCCGACT CCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCTTCATTAGTCACATGGGCACCT CTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGAAAGTGTGTGCCTCCGAGAAGC CGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTACCAATGAGGGCAGGGGAAGAC CACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTTGTCCCCGGCAGCAGGGAAGAA GCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGACGGGGACGGGAGGGGCCGGCC ACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTCGCCCCGCCCAGCCCCCTGGTG TGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACCTGTGCCTCCCCTCCCCCTTTG TTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCCTCAGTCTTTCCCCCACCCTGT >18682_18682_11_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964565_ENST00000229268_length(amino acids)=1004AA_BP=183 MFGRPSSGMHSSSPSPTNDRGLRRTIRLAPLSFGLRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQE MYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTV DFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVI LPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTD GSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRI GEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVP ESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIK KFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLV EMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLER AVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPP -------------------------------------------------------------- >18682_18682_12_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964565_ENST00000389231_length(transcript)=3494nt_BP=554nt AAAGCTTGTTTGGACGACCTTCGTCTGGGATGCACTCTTCTTCTCCTTCACCTACAAATGATAGAGGATTACGAAGAACTATACGGTTGG CTCCTCTTTCCTTTGGCCTTAGGTTTCTGACCTCCTGCAGCCTCCTCTTGCCTCGGGCTGCCCAGATCTTGGCGGCTGAGGCTGGCTTAC CTTCGAGCCGTTCCTTCATGGGATTTGCTGCTCCCTTCACCAACAAGCGAAAGGCTTACTCGGAGCGTAGAATCATGGGGTACTCAATGC AGGAGATGTATGAGGTGGTGTCCAACGTCCAGGAGTATCGTGAGTTTGTGCCCTGGTGTAAGAAGTCTCTGGTGGTATCCAGCCGTAAGG GTCATTTGAAAGCCCAGCTGGAGGTTGGCTTTCCACCTGTCATGGAACGTTACACCTCTGCAGTTTCCATGGTCAAACCTCACATGGTCA AGGCTGTTTGTACTGATGGCAAGCTCTTCAACCACTTAGAGACTATTTGGCGATTCAGCCCTGGTATTCCTGCCTATCCTCGAACCTGCA CTGTGGACTTTTCGGAGTCTGAGGGGGGCCTCTACATCTGTATGAACACGTTTCTGGGCTTTGGGAAACAGTATGTGGAGAGACATTTCA ATAAGACCGGCCAGCGAGTCTACTTGCACCTCCGGCGGACCCGGCGCCCGAAAGAGGAGGACCCTGCTACAGGCACTGGAGACCCACCCC GGAAGAAGCCCACGCGGCTGGCTATTGGTGTTGAAGGCGGATTTGACCTTAGCGAGGAGAAGTTTGAATTAGACGAGGATGTGAAGATTG TCATTTTGCCAGATTACCTGGAGATTGCCCGGGATGGACTGGGGGGACTGCCTGACATTGTCAGAGATCGGGTGACCAGTGCAGTGGAGG CCCTACTGTCGGCCGACTCAGCCTCCCGCAAGCAGGAGGTGCAGGCATGGGATGGGGAAGTACGGCAGGTGTCTAAGCATGCCTTCAGCC TCAAGCAGTTGGACAACCCTGCTCGAATCCCTCCCTGTGGCTGGAAGTGCTCCAAGTGTGACATGAGAGAGAACCTGTGGCTCAACCTGA CTGATGGCTCCATCCTCTGTGGGCGACGCTACTTCGATGGCAGTGGGGGCAACAACCACGCTGTGGAGCACTACCGAGAGACAGGCTACC CGTTAGCTGTCAAGCTGGGCACCATCACCCCTGATGGAGCTGACGTGTACTCATATGATGAGGATGACATGGTCCTGGACCCCAGCCTGG CTGAGCACCTGTCCCACTTCGGCATCGACATGCTGAAGATGCAGAAGACAGACAAGACGATGACTGAGTTGGAGATAGACATGAACCAGC GGATTGGTGAATGGGAGCTGATCCAGGAGTCAGGTGTGCCACTCAAGCCCCTGTTTGGGCCTGGCTACACAGGCATCCGGAACCTGGGTA ACAGCTGCTACCTCAACTCTGTGGTCCAGGTGCTCTTCAGCATCCCTGACTTCCAGAGGAAGTATGTGGATAAGCTGGAGAAGATCTTCC AGAATGCCCCGACGGACCCTACCCAGGATTTCAGCACCCAGGTGGCCAAGCTGGGCCATGGCCTTCTCTCCGGGGAGTATTCCAAGCCAG TACCGGAGTCGGGCGATGGGGAGCGGGTGCCAGAACAGAAGGAAGTTCAAGATGGCATTGCCCCTCGGATGTTCAAGGCCCTCATCGGCA AGGGCCACCCTGAATTCTCCACCAACCGGCAGCAGGATGCCCAGGAGTTCTTCCTTCACCTTATCAACATGGTGGAGAGGAATTGCCGGA GCTCTGAAAATCCTAATGAAGTGTTCCGCTTCTTGGTGGAGGAAAAGATCAAGTGCCTGGCCACAGAGAAGGTGAAGTACACCCAGCGAG TTGACTACATCATGCAGCTGCCTGTGCCCATGGATGCAGCCCTTAACAAAGAGGAGCTTCTGGAGTACGAGGAGAAGAAGCGGCAAGCCG AAGAGGAGAAGATGGCACTGCCAGAACTGGTTCGGGCCCAGGTGCCCTTCAGCTCTTGCCTGGAGGCCTACGGGGCCCCTGAGCAGGTCG ATGACTTCTGGAGCACGGCCCTGCAGGCCAAGTCAGTAGCTGTCAAGACCACACGATTTGCCTCATTCCCTGACTACCTGGTCATCCAGA TCAAGAAGTTCACCTTCGGCTTAGACTGGGTGCCCAAGAAACTGGATGTGTCCATCGAGATGCCAGAGGAGCTCGACATCTCCCAGTTGA GGGGCACAGGGCTGCAGCCCGGAGAGGAGGAGCTGCCAGACATTGCCCCACCCCTGGTCACTCCGGATGAGCCCAAAGCGCCCATGCTGG ATGAATCAGTCATCATCCAGCTGGTGGAGATGGGATTCCCTATGGACGCCTGCCGCAAAGCTGTCTACTACACGGGCAACAGCGGGGCTG AGGCCGCCATGAACTGGGTCATGTCACACATGGATGATCCAGATTTTGCAAACCCCCTCATCCTGCCTGGCTCTAGTGGGCCGGGCTCCA CAAGCGCAGCAGCCGACCCCCCTCCTGAGGACTGTGTGACCACCATTGTCTCCATGGGCTTCTCCCGGGACCAGGCCTTGAAAGCGCTGC GGGCCACGAACAATAGTTTAGAACGGGCTGTGGACTGGATCTTCAGTCACATTGACGACCTGGATGCTGAAGCTGCCATGGACATCTCAG AGGGCCGCTCAGCTGCCGACTCCATCTCTGAGTCTGTGCCAGTGGGACCTAAAGTCCGGGATGGTCCTGGAAAGTATCAGCTCTTTGCCT TCATTAGTCACATGGGCACCTCTACCATGTGTGGTCACTACGTCTGCCACATCAAGAAAGAAGGCAGATGGGTGATCTACAATGACCAGA AAGTGTGTGCCTCCGAGAAGCCGCCCAAGGACCTGGGCTACATCTACTTCTACCAGAGAGTGGCCAGCTAAGAGCCTGCCTCACCCCTTA CCAATGAGGGCAGGGGAAGACCACCTGGCATGAGGGAGAGGGGCTGAGGGATGGACTTCAGCCCCTCTGCTCTGTACCCTTTTTCCTTTT GTCCCCGGCAGCAGGGAAGAAGCTGGAGGCCGTGGGAGAATGGCTGGGCAGAGCAGAGGGGCAGCGATAGACTCTGGGGATGGAGCAGGA CGGGGACGGGAGGGGCCGGCCACCTGTCTGTAAGGAGACTTTGTTGCTTCCCCTGCCCCCGGAATCCACAGTGCTCTGCTTCTCTGTGTC GCCCCGCCCAGCCCCCTGGTGTGGAGGGAGGGGTCTCGTTTGTGCGCGTGGGTGTAGCTTTGTGCATCCTCTCCCAGTGGAGCGATCACC TGTGCCTCCCCTCCCCCTTTGTTTGCCCCTGTGTGGTTGGTCAAGGAGGGATGTGAGGGAAATAGGGACCCCCCGACTTGCCCTCCTGCC >18682_18682_12_COQ10A-USP5_COQ10A_chr12_56663345_ENST00000546544_USP5_chr12_6964565_ENST00000389231_length(amino acids)=981AA_BP=183 MFGRPSSGMHSSSPSPTNDRGLRRTIRLAPLSFGLRFLTSCSLLLPRAAQILAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQE MYEVVSNVQEYREFVPWCKKSLVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGIPAYPRTCTV DFSESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVI LPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTD GSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRI GEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVP ESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIK KFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKAPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEA AMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for COQ10A-USP5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for COQ10A-USP5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for COQ10A-USP5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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