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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CPS1-MAP2 (FusionGDB2 ID:19092)

Fusion Gene Summary for CPS1-MAP2

check button Fusion gene summary
Fusion gene informationFusion gene name: CPS1-MAP2
Fusion gene ID: 19092
HgeneTgene
Gene symbol

CPS1

MAP2

Gene ID

1589

10988

Gene namecytochrome P450 family 21 subfamily A member 2methionyl aminopeptidase 2
SynonymsCA21H|CAH1|CPS1|CYP21|CYP21B|P450c21BMAP2|MNPEP|p67eIF2
Cytomap

6p21.33

12q22

Type of geneprotein-codingprotein-coding
Descriptionsteroid 21-hydroxylase21-OHasecytochrome P450 XXIcytochrome P450, family 21, subfamily A, polypeptide 2cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2cytochrome P450-C21Bsteroid 21 hydroxylasemethionine aminopeptidase 2eIF-2-associated p67 homologinitiation factor 2-associated 67 kDa glycoproteinpeptidase M 2testicular tissue protein Li 17
Modification date2020032020200313
UniProtAcc.

O14733

Ensembl transtripts involved in fusion geneENST00000233072, ENST00000430249, 
ENST00000451903, ENST00000497121, 
ENST00000475600, ENST00000360351, 
ENST00000361559, ENST00000392194, 
ENST00000447185, ENST00000199940, 
Fusion gene scores* DoF score10 X 11 X 4=4407 X 8 X 4=224
# samples 118
** MAII scorelog2(11/440*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/224*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CPS1 [Title/Abstract] AND MAP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCPS1(211454958)-MAP2(210588319), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCPS1

GO:0006694

steroid biosynthetic process

25855791

TgeneMAP2

GO:0016485

protein processing

8858118

TgeneMAP2

GO:0018206

peptidyl-methionine modification

8858118

TgeneMAP2

GO:0031365

N-terminal protein amino acid modification

8858118


check buttonFusion gene breakpoints across CPS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MAP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-2Y-A9H6-01ACPS1chr2

211447433

+MAP2chr2

210570304

+
ChimerDB4LIHCTCGA-MR-A8JO-01ACPS1chr2

211454958

+MAP2chr2

210588319

+


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Fusion Gene ORF analysis for CPS1-MAP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000233072ENST00000475600CPS1chr2

211447433

+MAP2chr2

210570304

+
5CDS-3UTRENST00000233072ENST00000475600CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-3UTRENST00000430249ENST00000475600CPS1chr2

211447433

+MAP2chr2

210570304

+
5CDS-3UTRENST00000430249ENST00000475600CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000233072ENST00000360351CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000233072ENST00000361559CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000233072ENST00000392194CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000233072ENST00000447185CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000430249ENST00000360351CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000430249ENST00000361559CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000430249ENST00000392194CPS1chr2

211454958

+MAP2chr2

210588319

+
5CDS-intronENST00000430249ENST00000447185CPS1chr2

211454958

+MAP2chr2

210588319

+
In-frameENST00000233072ENST00000199940CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000233072ENST00000199940CPS1chr2

211454958

+MAP2chr2

210588319

+
In-frameENST00000233072ENST00000360351CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000233072ENST00000361559CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000233072ENST00000392194CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000233072ENST00000447185CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000430249ENST00000199940CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000430249ENST00000199940CPS1chr2

211454958

+MAP2chr2

210588319

+
In-frameENST00000430249ENST00000360351CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000430249ENST00000361559CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000430249ENST00000392194CPS1chr2

211447433

+MAP2chr2

210570304

+
In-frameENST00000430249ENST00000447185CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000451903ENST00000199940CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000451903ENST00000199940CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-3CDSENST00000451903ENST00000360351CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000451903ENST00000361559CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000451903ENST00000392194CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000451903ENST00000447185CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000497121ENST00000199940CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000497121ENST00000199940CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-3CDSENST00000497121ENST00000360351CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000497121ENST00000361559CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000497121ENST00000392194CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3CDSENST00000497121ENST00000447185CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3UTRENST00000451903ENST00000475600CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3UTRENST00000451903ENST00000475600CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-3UTRENST00000497121ENST00000475600CPS1chr2

211447433

+MAP2chr2

210570304

+
intron-3UTRENST00000497121ENST00000475600CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000451903ENST00000360351CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000451903ENST00000361559CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000451903ENST00000392194CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000451903ENST00000447185CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000497121ENST00000360351CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000497121ENST00000361559CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000497121ENST00000392194CPS1chr2

211454958

+MAP2chr2

210588319

+
intron-intronENST00000497121ENST00000447185CPS1chr2

211454958

+MAP2chr2

210588319

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000430249CPS1chr2211447433+ENST00000199940MAP2chr2210570304+1808694551686543
ENST00000430249CPS1chr2211447433+ENST00000360351MAP2chr2210570304+5315694551593512
ENST00000430249CPS1chr2211447433+ENST00000361559MAP2chr2210570304+1720694551593512
ENST00000430249CPS1chr2211447433+ENST00000392194MAP2chr2210570304+5315694551593512
ENST00000430249CPS1chr2211447433+ENST00000447185MAP2chr2210570304+1594694551593513
ENST00000233072CPS1chr2211447433+ENST00000199940MAP2chr2210570304+19318171961809537
ENST00000233072CPS1chr2211447433+ENST00000360351MAP2chr2210570304+54388171961716506
ENST00000233072CPS1chr2211447433+ENST00000361559MAP2chr2210570304+18438171961716506
ENST00000233072CPS1chr2211447433+ENST00000392194MAP2chr2210570304+54388171961716506
ENST00000233072CPS1chr2211447433+ENST00000447185MAP2chr2210570304+17178171961716507
ENST00000430249CPS1chr2211454958+ENST00000199940MAP2chr2210588319+1538913551416453
ENST00000233072CPS1chr2211454958+ENST00000199940MAP2chr2210588319+166110361961539447

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000430249ENST00000199940CPS1chr2211447433+MAP2chr2210570304+0.0017415470.9982584
ENST00000430249ENST00000360351CPS1chr2211447433+MAP2chr2210570304+0.0002739160.9997261
ENST00000430249ENST00000361559CPS1chr2211447433+MAP2chr2210570304+0.0021573460.99784267
ENST00000430249ENST00000392194CPS1chr2211447433+MAP2chr2210570304+0.0002739160.9997261
ENST00000430249ENST00000447185CPS1chr2211447433+MAP2chr2210570304+0.00282630.99717367
ENST00000233072ENST00000199940CPS1chr2211447433+MAP2chr2210570304+0.0013974610.99860257
ENST00000233072ENST00000360351CPS1chr2211447433+MAP2chr2210570304+0.0002944390.9997055
ENST00000233072ENST00000361559CPS1chr2211447433+MAP2chr2210570304+0.0016591180.99834085
ENST00000233072ENST00000392194CPS1chr2211447433+MAP2chr2210570304+0.0002944390.9997055
ENST00000233072ENST00000447185CPS1chr2211447433+MAP2chr2210570304+0.0019559060.99804413
ENST00000430249ENST00000199940CPS1chr2211454958+MAP2chr2210588319+0.0008708980.9991291
ENST00000233072ENST00000199940CPS1chr2211454958+MAP2chr2210588319+0.0006177960.99938214

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Fusion Genomic Features for CPS1-MAP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CPS1chr2211454958+MAP2chr2210588318+0.037214850.9627851
CPS1chr2211447433+MAP2chr2210570303+0.0033014240.99669856
CPS1chr2211454958+MAP2chr2210588318+0.037214850.9627851
CPS1chr2211447433+MAP2chr2210570303+0.0033014240.99669856

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CPS1-MAP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:211454958/chr2:210588319)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MAP2

O14733

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Part of a non-canonical MAPK signaling pathway, composed of the upstream MAP3K12 kinase and downstream MAP kinases MAPK1/ERK2 and MAPK3/ERK1, that enhances the AP-1-mediated transcription of APP in response to APOE (PubMed:28111074). {ECO:0000269|PubMed:28111074, ECO:0000269|PubMed:9312068, ECO:0000269|PubMed:9372971, ECO:0000269|PubMed:9535930, ECO:0000269|Ref.5}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPS1chr2:211454958chr2:210588319ENST00000233072+83839_2182801501.0RegionNote=Anthranilate phosphoribosyltransferase homolog
HgeneCPS1chr2:211454958chr2:210588319ENST00000430249+93939_2182861507.0RegionNote=Anthranilate phosphoribosyltransferase homolog
TgeneMAP2chr2:211447433chr2:210570304ENST000001999408151447_1467229560.0RegionCalmodulin-binding
TgeneMAP2chr2:211447433chr2:210570304ENST000003615596121447_1467172472.0RegionCalmodulin-binding
TgeneMAP2chr2:211447433chr2:210570304ENST000003921945111447_1467172472.0RegionCalmodulin-binding
TgeneMAP2chr2:211454958chr2:210588319ENST0000019994010151447_1467392560.0RegionCalmodulin-binding
TgeneMAP2chr2:211454958chr2:210588319ENST000003603510151447_146701828.0RegionCalmodulin-binding
TgeneMAP2chr2:211454958chr2:210588319ENST000003615590121447_14670472.0RegionCalmodulin-binding
TgeneMAP2chr2:211454958chr2:210588319ENST000003921940111447_14670472.0RegionCalmodulin-binding
TgeneMAP2chr2:211454958chr2:210588319ENST000004471850121447_146701824.0RegionCalmodulin-binding
TgeneMAP2chr2:211447433chr2:210570304ENST000001999408151661_1691229560.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211447433chr2:210570304ENST000001999408151692_1722229560.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211447433chr2:210570304ENST000001999408151723_1754229560.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211447433chr2:210570304ENST000003603519151661_169115281828.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211447433chr2:210570304ENST000003603519151692_172215281828.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211447433chr2:210570304ENST000003603519151723_175415281828.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211447433chr2:210570304ENST000003615596121661_1691172472.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211447433chr2:210570304ENST000003615596121692_1722172472.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211447433chr2:210570304ENST000003615596121723_1754172472.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211447433chr2:210570304ENST000003921945111661_1691172472.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211447433chr2:210570304ENST000003921945111692_1722172472.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211447433chr2:210570304ENST000003921945111723_1754172472.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211447433chr2:210570304ENST000004471856121661_169115241824.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211447433chr2:210570304ENST000004471856121692_172215241824.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211447433chr2:210570304ENST000004471856121723_175415241824.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211454958chr2:210588319ENST0000019994010151661_1691392560.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211454958chr2:210588319ENST0000019994010151692_1722392560.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211454958chr2:210588319ENST0000019994010151723_1754392560.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211454958chr2:210588319ENST000003603510151661_169101828.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211454958chr2:210588319ENST000003603510151692_172201828.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211454958chr2:210588319ENST000003603510151723_175401828.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211454958chr2:210588319ENST000003615590121661_16910472.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211454958chr2:210588319ENST000003615590121692_17220472.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211454958chr2:210588319ENST000003615590121723_17540472.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211454958chr2:210588319ENST000003921940111661_16910472.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211454958chr2:210588319ENST000003921940111692_17220472.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211454958chr2:210588319ENST000003921940111723_17540472.0RepeatNote=Tau/MAP 3
TgeneMAP2chr2:211454958chr2:210588319ENST000004471850121661_169101824.0RepeatNote=Tau/MAP 1
TgeneMAP2chr2:211454958chr2:210588319ENST000004471850121692_172201824.0RepeatNote=Tau/MAP 2
TgeneMAP2chr2:211454958chr2:210588319ENST000004471850121723_175401824.0RepeatNote=Tau/MAP 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPS1chr2:211447433chr2:210570304ENST00000233072+6381093_12842071501.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211447433chr2:210570304ENST00000233072+6381355_15002071501.0DomainMGS-like
HgeneCPS1chr2:211447433chr2:210570304ENST00000233072+638219_4042071501.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211447433chr2:210570304ENST00000233072+638551_7432071501.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211447433chr2:210570304ENST00000430249+7391093_12842131507.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211447433chr2:210570304ENST00000430249+7391355_15002131507.0DomainMGS-like
HgeneCPS1chr2:211447433chr2:210570304ENST00000430249+739219_4042131507.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211447433chr2:210570304ENST00000430249+739551_7432131507.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211447433chr2:210570304ENST00000451903+1281093_128401050.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211447433chr2:210570304ENST00000451903+1281355_150001050.0DomainMGS-like
HgeneCPS1chr2:211447433chr2:210570304ENST00000451903+128219_40401050.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211447433chr2:210570304ENST00000451903+128551_74301050.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211454958chr2:210588319ENST00000233072+8381093_12842801501.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211454958chr2:210588319ENST00000233072+8381355_15002801501.0DomainMGS-like
HgeneCPS1chr2:211454958chr2:210588319ENST00000233072+838219_4042801501.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211454958chr2:210588319ENST00000233072+838551_7432801501.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211454958chr2:210588319ENST00000430249+9391093_12842861507.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211454958chr2:210588319ENST00000430249+9391355_15002861507.0DomainMGS-like
HgeneCPS1chr2:211454958chr2:210588319ENST00000430249+939219_4042861507.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211454958chr2:210588319ENST00000430249+939551_7432861507.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211454958chr2:210588319ENST00000451903+1281093_128401050.0DomainNote=ATP-grasp 2
HgeneCPS1chr2:211454958chr2:210588319ENST00000451903+1281355_150001050.0DomainMGS-like
HgeneCPS1chr2:211454958chr2:210588319ENST00000451903+128219_40401050.0DomainNote=Glutamine amidotransferase type-1
HgeneCPS1chr2:211454958chr2:210588319ENST00000451903+128551_74301050.0DomainNote=ATP-grasp 1
HgeneCPS1chr2:211447433chr2:210570304ENST00000233072+63839_2182071501.0RegionNote=Anthranilate phosphoribosyltransferase homolog
HgeneCPS1chr2:211447433chr2:210570304ENST00000430249+73939_2182131507.0RegionNote=Anthranilate phosphoribosyltransferase homolog
HgeneCPS1chr2:211447433chr2:210570304ENST00000451903+12839_21801050.0RegionNote=Anthranilate phosphoribosyltransferase homolog
HgeneCPS1chr2:211454958chr2:210588319ENST00000451903+12839_21801050.0RegionNote=Anthranilate phosphoribosyltransferase homolog
TgeneMAP2chr2:211447433chr2:210570304ENST000003603519151447_146715281828.0RegionCalmodulin-binding
TgeneMAP2chr2:211447433chr2:210570304ENST000004471856121447_146715241824.0RegionCalmodulin-binding


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Fusion Gene Sequence for CPS1-MAP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19092_19092_1_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000199940_length(transcript)=1931nt_BP=817nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGG
AGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGG
GAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCAC
TCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCAT
CATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAA
AATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTC
CAGATGTGGTTCCAAGGATAACATCAAACATTCGGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGAC
ATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAA
GGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAG
AGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAG
CAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCA
GGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATT

>19092_19092_1_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000199940_length(amino acids)=537AA_BP=207
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTS
TPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTD
NIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKV

--------------------------------------------------------------
>19092_19092_2_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000360351_length(transcript)=5438nt_BP=817nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGG
AGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGG
GAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCAC
TCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCAT
CATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAA
AATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATC
CAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGC
CCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGA
GCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAA
TGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGG
CTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCAT
TCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATGCAGAA
ATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGG
AGTATTATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTG
CTCATTTCACTATTCTGTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGC
AGGAAGGGAAGAGCATGTAAGAAATAAGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTG
GGACCTGGATAATTATATCAGAGTATGTCAGTCCAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAG
GAAGTGGTGTAAAAGTGCATCCATTAGGAATGATGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGAT
TTGTGTCCACACTACCAGTTTCACACCCCCTTTCCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCAT
TTGTGATACTTCCTCATATACTTGAATATTATACTTCTTTATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATA
TGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGT
AACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTTCACCA
ACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCA
CAGGATAGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAG
TTGAAAGTTGAAACTAACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATG
TTTGTCTTTCTTACCCAAAGTAAAGATCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACA
CAGATATCTAAATCAGTTTTTTTCCAAGACTCCAACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAA
TACTGTTCTGACTGTATATACAGTCTAGAACTCACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATG
AAATAGTCAATGGCCTGATTAAGGCAAAGAGCTACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGC
TGGTAGGTTGGATCTGAACCATTAAAATCAAATGGTCCACTAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGA
AATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTT
TGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAGAGATT
TTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTA
TTTTCTGCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAA
GAAAGGTGTGTGGAGACTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTC
ATTAGAAAAGTTTTAACCTGTGAAATAAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCAT
ACTAGAAGTCAGTTTATTACAAATACATGTCAAAAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTA
TTTCTAATCACAACAAAATTATAATGAATAAATGTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGAT
CGTTTGTACCAGTAAAAGAGAGAAACACACAGGTTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGA
TAACGACTCAAATTAAGCTTTTTGAGCACCACTCTTGTGGGGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTA
GATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGG
CCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTCATGAT
GAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTA
CAAGTATGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAG
TGACCTTCTCCACACACACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATT
CCATCAGTATTTTATTAAGGAAATAACCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAAT
AAGGAAAATAAACTACTCATGGTCTAAATACTAGAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTG
ACGTGCTAAAATAAGCATTGATGTTTTGAGTTTTTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAG
GAAAAAGCTTATTTTCAAACTCAGAAAATAAAATGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAA
GTATACTCTGTATGCTGGGATTCCGAGGTTCCAACACACTGTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTT
ACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGAT

>19092_19092_2_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000360351_length(amino acids)=506AA_BP=207
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTS
TPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTD
NIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKAR

--------------------------------------------------------------
>19092_19092_3_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000361559_length(transcript)=1843nt_BP=817nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGG
AGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGG
GAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCAC
TCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCAT
CATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAA
AATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATC
CAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGC
CCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGA
GCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAA
TGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGG
CTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCAT

>19092_19092_3_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000361559_length(amino acids)=506AA_BP=207
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTS
TPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTD
NIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKAR

--------------------------------------------------------------
>19092_19092_4_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000392194_length(transcript)=5438nt_BP=817nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGG
AGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGG
GAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCAC
TCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCAT
CATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAA
AATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATC
CAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGC
CCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGA
GCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAA
TGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGG
CTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCAT
TCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATGCAGAA
ATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGG
AGTATTATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTG
CTCATTTCACTATTCTGTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGC
AGGAAGGGAAGAGCATGTAAGAAATAAGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTG
GGACCTGGATAATTATATCAGAGTATGTCAGTCCAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAG
GAAGTGGTGTAAAAGTGCATCCATTAGGAATGATGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGAT
TTGTGTCCACACTACCAGTTTCACACCCCCTTTCCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCAT
TTGTGATACTTCCTCATATACTTGAATATTATACTTCTTTATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATA
TGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGT
AACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTTCACCA
ACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCA
CAGGATAGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAG
TTGAAAGTTGAAACTAACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATG
TTTGTCTTTCTTACCCAAAGTAAAGATCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACA
CAGATATCTAAATCAGTTTTTTTCCAAGACTCCAACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAA
TACTGTTCTGACTGTATATACAGTCTAGAACTCACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATG
AAATAGTCAATGGCCTGATTAAGGCAAAGAGCTACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGC
TGGTAGGTTGGATCTGAACCATTAAAATCAAATGGTCCACTAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGA
AATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTT
TGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAGAGATT
TTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTA
TTTTCTGCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAA
GAAAGGTGTGTGGAGACTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTC
ATTAGAAAAGTTTTAACCTGTGAAATAAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCAT
ACTAGAAGTCAGTTTATTACAAATACATGTCAAAAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTA
TTTCTAATCACAACAAAATTATAATGAATAAATGTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGAT
CGTTTGTACCAGTAAAAGAGAGAAACACACAGGTTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGA
TAACGACTCAAATTAAGCTTTTTGAGCACCACTCTTGTGGGGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTA
GATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGG
CCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTCATGAT
GAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTA
CAAGTATGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAG
TGACCTTCTCCACACACACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATT
CCATCAGTATTTTATTAAGGAAATAACCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAAT
AAGGAAAATAAACTACTCATGGTCTAAATACTAGAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTG
ACGTGCTAAAATAAGCATTGATGTTTTGAGTTTTTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAG
GAAAAAGCTTATTTTCAAACTCAGAAAATAAAATGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAA
GTATACTCTGTATGCTGGGATTCCGAGGTTCCAACACACTGTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTT
ACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGAT

>19092_19092_4_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000392194_length(amino acids)=506AA_BP=207
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTS
TPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTD
NIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKAR

--------------------------------------------------------------
>19092_19092_5_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000447185_length(transcript)=1717nt_BP=817nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGG
AGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGG
GAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCAC
TCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCAT
CATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAA
AATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATC
CAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGC
CCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGA
GCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAA
TGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGG

>19092_19092_5_CPS1-MAP2_CPS1_chr2_211447433_ENST00000233072_MAP2_chr2_210570304_ENST00000447185_length(amino acids)=507AA_BP=207
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTS
TPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTD
NIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKAR

--------------------------------------------------------------
>19092_19092_6_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000199940_length(transcript)=1808nt_BP=694nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGACGGAGTAACCAAGAGCCCAGAAAA
GCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAG
TTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGG
GTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCA
CACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCC
CAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAATACCAGCC
TAAAGGGGGGCAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTCCAGATGTGGTTCCAAGGATAACATCAAACATTC
GGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCA
CAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGC
TCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGC
TGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCT
CGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAA
TAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCA

>19092_19092_6_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000199940_length(amino acids)=543AA_BP=213
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA
GKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS
KIGSTDNIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKE
KAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAK

--------------------------------------------------------------
>19092_19092_7_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000360351_length(transcript)=5315nt_BP=694nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGACGGAGTAACCAAGAGCCCAGAAAA
GCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAG
TTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGG
GTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCA
CACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCC
CAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAATACCAGCC
TAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAG
GCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCA
TCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGA
GATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGA
ATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAA
TAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCC
CCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATGCAGAAATTGACCTGATTTCCATTTGCAACAGGAAGACA
CTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGGAGTATTATTATTTTAAAAATTGCATTTTTACCT
TTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTGCTCATTTCACTATTCTGTTTCTGAGTGAGAAGA
TAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGCAGGAAGGGAAGAGCATGTAAGAAATAAGTTTTT
TTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGACCTGGATAATTATATCAGAGTATGTCAGTC
CAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAAAGTGCATCCATTAGGAATGA
TGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCACACCCCCTTT
CCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATA
CTTCTTTATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCT
ATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCC
AGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTTCACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATAC
ATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCACAGGATAGTTTGGGGTTTATTCCTATTATTATT
CATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAGTTGAAAGTTGAAACTAACTATAATAGTTTGAAA
CATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATGTTTGTCTTTCTTACCCAAAGTAAAGATCCCCTG
ATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAGATATCTAAATCAGTTTTTTTCCAAGACTCC
AACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACTGTATATACAGTCTAGAACTC
ACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAGGCAAAGAGCT
ACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAAT
GGTCCACTAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGT
ATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAAC
TGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAGAGATTTTACACAGGCAAACGTGTCTTAAACCATCTATA
AATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTATTTTCTGCCTATTAATTGCTGTGAGGTTTGATT
TGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAAGAAAGGTGTGTGGAGACTTAGGGTATTTTATTA
CATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTCATTAGAAAAGTTTTAACCTGTGAAATAAGTATT
TTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACTAGAAGTCAGTTTATTACAAATACATGTCAA
AAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAACAAAATTATAATGAATAAAT
GTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGAAACACACAGG
TTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACT
CTTGTGGGGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGC
CTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCA
CTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTCATGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAA
CTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTACAAGTATGACACCTGTGTAACACCAGCTAGGTA
CGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAGTGACCTTCTCCACACACACACACACACACACAC
ACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATTCCATCAGTATTTTATTAAGGAAATAACCTGAAT
GTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAGGAAAATAAACTACTCATGGTCTAAATACTA
GAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATAAGCATTGATGTTTTGAGTTT
TTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCAGAAAATAAAA
TGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCA
ACACACTGTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTG
TAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCTAAC

>19092_19092_7_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000360351_length(amino acids)=512AA_BP=213
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA
GKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS
KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFR

--------------------------------------------------------------
>19092_19092_8_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000361559_length(transcript)=1720nt_BP=694nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGACGGAGTAACCAAGAGCCCAGAAAA
GCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAG
TTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGG
GTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCA
CACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCC
CAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAATACCAGCC
TAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAG
GCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCA
TCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGA
GATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGA
ATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAA
TAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCC

>19092_19092_8_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000361559_length(amino acids)=512AA_BP=213
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA
GKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS
KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFR

--------------------------------------------------------------
>19092_19092_9_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000392194_length(transcript)=5315nt_BP=694nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGACGGAGTAACCAAGAGCCCAGAAAA
GCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAG
TTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGG
GTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCA
CACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCC
CAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAATACCAGCC
TAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAG
GCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCA
TCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGA
GATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGA
ATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAA
TAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCC
CCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATGCAGAAATTGACCTGATTTCCATTTGCAACAGGAAGACA
CTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGGAGTATTATTATTTTAAAAATTGCATTTTTACCT
TTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTGCTCATTTCACTATTCTGTTTCTGAGTGAGAAGA
TAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGCAGGAAGGGAAGAGCATGTAAGAAATAAGTTTTT
TTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGACCTGGATAATTATATCAGAGTATGTCAGTC
CAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAAAGTGCATCCATTAGGAATGA
TGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCACACCCCCTTT
CCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATA
CTTCTTTATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCT
ATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCC
AGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTTCACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATAC
ATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCACAGGATAGTTTGGGGTTTATTCCTATTATTATT
CATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAGTTGAAAGTTGAAACTAACTATAATAGTTTGAAA
CATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATGTTTGTCTTTCTTACCCAAAGTAAAGATCCCCTG
ATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAGATATCTAAATCAGTTTTTTTCCAAGACTCC
AACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACTGTATATACAGTCTAGAACTC
ACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAGGCAAAGAGCT
ACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAAT
GGTCCACTAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGT
ATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAAC
TGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAGAGATTTTACACAGGCAAACGTGTCTTAAACCATCTATA
AATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTATTTTCTGCCTATTAATTGCTGTGAGGTTTGATT
TGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAAGAAAGGTGTGTGGAGACTTAGGGTATTTTATTA
CATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTCATTAGAAAAGTTTTAACCTGTGAAATAAGTATT
TTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACTAGAAGTCAGTTTATTACAAATACATGTCAA
AAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAACAAAATTATAATGAATAAAT
GTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGAAACACACAGG
TTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACT
CTTGTGGGGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGC
CTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCA
CTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTCATGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAA
CTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTACAAGTATGACACCTGTGTAACACCAGCTAGGTA
CGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAGTGACCTTCTCCACACACACACACACACACACAC
ACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATTCCATCAGTATTTTATTAAGGAAATAACCTGAAT
GTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAGGAAAATAAACTACTCATGGTCTAAATACTA
GAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATAAGCATTGATGTTTTGAGTTT
TTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCAGAAAATAAAA
TGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCA
ACACACTGTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTG
TAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCTAAC

>19092_19092_9_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000392194_length(amino acids)=512AA_BP=213
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA
GKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS
KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFR

--------------------------------------------------------------
>19092_19092_10_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000447185_length(transcript)=1594nt_BP=694nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGACGGAGTAACCAAGAGCCCAGAAAA
GCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAG
TTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGG
GTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCA
CACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCC
CAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAATACCAGCC
TAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAG
GCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCA
TCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGA
GATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGA

>19092_19092_10_CPS1-MAP2_CPS1_chr2_211447433_ENST00000430249_MAP2_chr2_210570304_ENST00000447185_length(amino acids)=513AA_BP=213
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA
GKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS
KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFR

--------------------------------------------------------------
>19092_19092_11_CPS1-MAP2_CPS1_chr2_211454958_ENST00000233072_MAP2_chr2_210588319_ENST00000199940_length(transcript)=1661nt_BP=1036nt
GGGGTTAAGAGAAGGAGGAGCTGTGGCTGAAGACATTTAATGGCAGAATGAATGGAAATTCAAAGATCGCTGTGCAGTCAGCCTTAAACA
CTGACTGCACCCCTCCCAGATTTCTTTTACATTAACTAAAAAGTCTTATCACACAATCTCATAAAATTTATGTAATTTCATTTAATTTTA
GCCACAAATCATCAAAATGACGAGGATTTTGACAGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGC
ACACCAAAAATGGAAATTTTCAAGACCTGGCATCAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAA
GATGAAAGGTTACTCCTTTGGCCATCCATCCTCTGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTAC
TGACCCTGCCTACAAAGGACAGATTCTCACAATGGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACT
GGGACTTAGCAAATATTTGGAGTCTAATGGAATCAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGC
TACCAAGAGTTTAGGGCAATGGCTACAGGAAGAAAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGA
TAAGGGTACCATGCTTGGGAAGATTGAATTTGAAGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTC
AACCAAGGATGTCAAAGTGTACGGCAAAGGAAACCCCACAAAAGTGGTAGCTGTAGACTGTGGGATTAAAAACAATGTAATCCGCCTGCT
AGTAAAGCGAGGAGCTGAAGTGCACTTAGTTCCCTGGAACCATGATTTCACCAAGATGGAGTATGATGGGATTTTGATCGCGGGAGGACC
GGGGAACCCAGCTCTTGCAGAACCACTAATTCAGAATGTCAGAAAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTC
CAGATGTGGTTCCAAGGATAACATCAAACATTCGGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGAC
ATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAA
GGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAG
AGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAG
CAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCA
GGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATT

>19092_19092_11_CPS1-MAP2_CPS1_chr2_211454958_ENST00000233072_MAP2_chr2_210588319_ENST00000199940_length(amino acids)=447AA_BP=280
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYK
GQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTML
GKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPAL
AEPLIQNVRKVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKV

--------------------------------------------------------------
>19092_19092_12_CPS1-MAP2_CPS1_chr2_211454958_ENST00000430249_MAP2_chr2_210588319_ENST00000199940_length(transcript)=1538nt_BP=913nt
GAAATGTAGTTGCTTTCTTAACCTCATCAAATTCATGAAGATTTAGCCGAGGCCCATGCCACAAATCATCAAAATGACGAGGATTTTGAC
AGCTTTCAAAGTGGTGAGGACACTGAAGACTGGTTTTGGCTTTACCAATGTGACTGCACACCAAAAATGGAAATTTTCAAGACCTGGCAT
CAGGCTCCTTTCTGTCAAGGCACAGACAGCACACATTGTCCTGGAAGATGGAACTAAGATGAAAGGTTACTCCTTTGGCCATCCATCCTC
TGTTGCTGGTGAAGTGGTTTTTAATACTGGCCTGGGAGGGTACCCAGAAGCTATTACTGACCCTGCCTACAAAGGACAGATTCTCACAAT
GGCCAACCCTATTATTGGGAATGGTGGAGCTCCTGATACTACTGCTCTGGATGAACTGGGACTTAGCAAATATTTGGAGTCTAATGGAAT
CAAGGTTTCAGGTTTGCTGGTGCTGGATTATAGTAAAGACTACAACCACTGGCTGGCTACCAAGAGTTTAGGGCAATGGCTACAGGAAGA
AAAGGTTCCTGCAATTTATGGAGTGGACACAAGAATGCTGACTAAAATAATTCGGGATAAGGGTACCATGCTTGGGAAGATTGAATTTGA
AGGTCAGCCTGTGGATTTTGTGGATCCAAATAAACAGAATTTGATTGCTGAGGTTTCAACCAAGGATGTCAAAGTGTACGGCAAAGGAAA
CCCCACAAAAGTGGTAGCTGTAGACTGTGGGATTAAAAACAATGTAATCCGCCTGCTAGTAAAGCGAGGAGCTGAAGTGCACTTAGTTCC
CTGGAACCATGATTTCACCAAGATGGAGTATGATGGGATTTTGATCGCGGGAGGACCGGGGAACCCAGCTCTTGCAGAACCACTAATTCA
GAATGTCAGAAAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTCCAGATGTGGTTCCAAGGATAACATCAAACATTC
GGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCA
CAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGC
TCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGC
TGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCT
CGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAA
TAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCA

>19092_19092_12_CPS1-MAP2_CPS1_chr2_211454958_ENST00000430249_MAP2_chr2_210588319_ENST00000199940_length(amino acids)=453AA_BP=286
MPQIIKMTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAI
TDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIR
DKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGG
PGNPALAEPLIQNVRKVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKE
KAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CPS1-MAP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMAP2chr2:211447433chr2:210570304ENST00000199940815701_744229.0560.0KNDC1
TgeneMAP2chr2:211447433chr2:210570304ENST00000361559612701_744172.0472.0KNDC1
TgeneMAP2chr2:211447433chr2:210570304ENST00000392194511701_744172.0472.0KNDC1
TgeneMAP2chr2:211454958chr2:210588319ENST000001999401015701_744392.0560.0KNDC1
TgeneMAP2chr2:211454958chr2:210588319ENST00000360351015701_74401828.0KNDC1
TgeneMAP2chr2:211454958chr2:210588319ENST00000361559012701_7440472.0KNDC1
TgeneMAP2chr2:211454958chr2:210588319ENST00000392194011701_7440472.0KNDC1
TgeneMAP2chr2:211454958chr2:210588319ENST00000447185012701_7440.01824.0KNDC1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneMAP2chr2:211447433chr2:210570304ENST00000360351915701_7441528.01828.0KNDC1
TgeneMAP2chr2:211447433chr2:210570304ENST00000447185612701_7441524.01824.0KNDC1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CPS1-MAP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CPS1-MAP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource