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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CPSF6-EZH2 (FusionGDB2 ID:19155)

Fusion Gene Summary for CPSF6-EZH2

check button Fusion gene summary
Fusion gene informationFusion gene name: CPSF6-EZH2
Fusion gene ID: 19155
HgeneTgene
Gene symbol

CPSF6

EZH2

Gene ID

11052

2146

Gene namecleavage and polyadenylation specific factor 6enhancer of zeste 2 polycomb repressive complex 2 subunit
SynonymsCFIM|CFIM68|CFIM72|HPBRII-4|HPBRII-7ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2
Cytomap

12q15

7q36.1

Type of geneprotein-codingprotein-coding
Descriptioncleavage and polyadenylation specificity factor subunit 6CPSF 68 kDa subunitcleavage and polyadenylation specific factor 6, 68kDacleavage and polyadenylation specificity factor 68 kDa subunitcleavage factor Im complex 68 kDa subunitpre-mRNA cleavage histone-lysine N-methyltransferase EZH2enhancer of zeste homolog 2lysine N-methyltransferase 6
Modification date2020031320200329
UniProtAcc

Q16630

Q15910

Ensembl transtripts involved in fusion geneENST00000266679, ENST00000435070, 
ENST00000456847, ENST00000551516, 
ENST00000550987, 		ENST00000320356, 
ENST00000350995, ENST00000460911, 
ENST00000476773, ENST00000478654, 
ENST00000483967, ENST00000541220, 
ENST00000536783, 
Fusion gene scores* DoF score69 X 12 X 19=1573210 X 7 X 5=350
# samples 719
** MAII scorelog2(71/15732*10)=-4.46973925655087
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/350*10)=-1.95935801550265
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CPSF6 [Title/Abstract] AND EZH2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCPSF6(69656342)-EZH2(148512638), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCPSF6

GO:0006397

mRNA processing

14690600

HgeneCPSF6

GO:0051262

protein tetramerization

20695905

HgeneCPSF6

GO:0051290

protein heterotetramerization

23187700

HgeneCPSF6

GO:1990120

messenger ribonucleoprotein complex assembly

29276085

TgeneEZH2

GO:0000122

negative regulation of transcription by RNA polymerase II

20154697

TgeneEZH2

GO:0010718

positive regulation of epithelial to mesenchymal transition

20154697

TgeneEZH2

GO:0043406

positive regulation of MAP kinase activity

20154697

TgeneEZH2

GO:0043547

positive regulation of GTPase activity

20154697

TgeneEZH2

GO:0045814

negative regulation of gene expression, epigenetic

20154697

TgeneEZH2

GO:0070734

histone H3-K27 methylation

24474760

TgeneEZH2

GO:0071902

positive regulation of protein serine/threonine kinase activity

20154697


check buttonFusion gene breakpoints across CPSF6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EZH2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CR-6467CPSF6chr12

69656342

+EZH2chr7

148512638

-


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Fusion Gene ORF analysis for CPSF6-EZH2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000266679ENST00000320356CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000350995CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000460911CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000476773CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000478654CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000483967CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000266679ENST00000541220CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000320356CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000350995CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000460911CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000476773CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000478654CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000483967CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000435070ENST00000541220CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000320356CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000350995CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000460911CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000476773CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000478654CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000483967CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-3CDSENST00000456847ENST00000541220CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-intronENST00000266679ENST00000536783CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-intronENST00000435070ENST00000536783CPSF6chr12

69656342

+EZH2chr7

148512638

-
3UTR-intronENST00000456847ENST00000536783CPSF6chr12

69656342

+EZH2chr7

148512638

-
5CDS-intronENST00000551516ENST00000536783CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000320356CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000350995CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000460911CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000476773CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000478654CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000483967CPSF6chr12

69656342

+EZH2chr7

148512638

-
In-frameENST00000551516ENST00000541220CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000320356CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000350995CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000460911CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000476773CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000478654CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000483967CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-3CDSENST00000550987ENST00000541220CPSF6chr12

69656342

+EZH2chr7

148512638

-
intron-intronENST00000550987ENST00000536783CPSF6chr12

69656342

+EZH2chr7

148512638

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000551516CPSF6chr1269656342+ENST00000478654EZH2chr7148512638-10591725796263
ENST00000551516CPSF6chr1269656342+ENST00000460911EZH2chr7148512638-11841725922305
ENST00000551516CPSF6chr1269656342+ENST00000350995EZH2chr7148512638-11841725922305
ENST00000551516CPSF6chr1269656342+ENST00000320356EZH2chr7148512638-11841725922305
ENST00000551516CPSF6chr1269656342+ENST00000541220EZH2chr7148512638-10581725796263
ENST00000551516CPSF6chr1269656342+ENST00000476773EZH2chr7148512638-9611725796263
ENST00000551516CPSF6chr1269656342+ENST00000483967EZH2chr7148512638-10441725922305

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000551516ENST00000478654CPSF6chr1269656342+EZH2chr7148512638-0.0045348360.9954652
ENST00000551516ENST00000460911CPSF6chr1269656342+EZH2chr7148512638-0.0021382560.9978618
ENST00000551516ENST00000350995CPSF6chr1269656342+EZH2chr7148512638-0.0021382560.9978618
ENST00000551516ENST00000320356CPSF6chr1269656342+EZH2chr7148512638-0.0021382560.9978618
ENST00000551516ENST00000541220CPSF6chr1269656342+EZH2chr7148512638-0.0045608740.9954391
ENST00000551516ENST00000476773CPSF6chr1269656342+EZH2chr7148512638-0.005894750.9941052
ENST00000551516ENST00000483967CPSF6chr1269656342+EZH2chr7148512638-0.0032411270.9967589

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Fusion Genomic Features for CPSF6-EZH2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CPSF6-EZH2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:69656342/chr7:148512638)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CPSF6

Q16630

EZH2

Q15910

FUNCTION: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs (PubMed:9659921, PubMed:8626397, PubMed:14690600, PubMed:29276085). CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals) (PubMed:9659921, PubMed:8626397, PubMed:14690600). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation (PubMed:23187700, PubMed:29276085). The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs (PubMed:20695905, PubMed:29276085). CPSF6 enhances NUDT21/CPSF5 binding to 5'-UGUA-3' elements localized upstream of pA signals and promotes RNA looping, and hence activates directly the mRNA 3'-processing machinery (PubMed:15169763, PubMed:29276085, PubMed:21295486). Plays a role in mRNA export (PubMed:19864460). {ECO:0000269|PubMed:14690600, ECO:0000269|PubMed:15169763, ECO:0000269|PubMed:19864460, ECO:0000269|PubMed:20695905, ECO:0000269|PubMed:21295486, ECO:0000269|PubMed:23187700, ECO:0000269|PubMed:29276085, ECO:0000269|PubMed:8626397, ECO:0000269|PubMed:9659921}.; FUNCTION: (Microbial infection) Binds HIV-1 capsid-nucleocapsid (HIV-1 CA-NC) complexes and might thereby promote the integration of the virus in the nucleus of dividing cells (in vitro). {ECO:0000269|PubMed:24130490}.FUNCTION: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2 (PubMed:22323599, PubMed:30923826). Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. Regulates the circadian clock via histone methylation at the promoter of the circadian genes. Essential for the CRY1/2-mediated repression of the transcriptional activation of PER1/2 by the CLOCK-ARNTL/BMAL1 heterodimer; involved in the di and trimethylation of 'Lys-27' of histone H3 on PER1/2 promoters which is necessary for the CRY1/2 proteins to inhibit transcription. {ECO:0000269|PubMed:14532106, ECO:0000269|PubMed:15225548, ECO:0000269|PubMed:15231737, ECO:0000269|PubMed:15385962, ECO:0000269|PubMed:16179254, ECO:0000269|PubMed:16357870, ECO:0000269|PubMed:16618801, ECO:0000269|PubMed:16717091, ECO:0000269|PubMed:16936726, ECO:0000269|PubMed:17210787, ECO:0000269|PubMed:17344414, ECO:0000269|PubMed:18285464, ECO:0000269|PubMed:19026781, ECO:0000269|PubMed:20935635, ECO:0000269|PubMed:22323599, ECO:0000269|PubMed:23063525, ECO:0000269|PubMed:24474760, ECO:0000269|PubMed:30923826}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011208_398590701.3333333333334Compositional biasNote=Pro-rich
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011490_551590701.3333333333334Compositional biasNote=Arg-rich
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910208_3985532111.0Compositional biasNote=Pro-rich
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910490_5515532111.0Compositional biasNote=Arg-rich
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011202_206590701.3333333333334MotifGAR
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910202_2065532111.0MotifGAR
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011358_551590701.3333333333334Region(Microbial infection) Binds to HIV-1 capsid protein p24 (CA)
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011404_551590701.3333333333334RegionSufficient for nuclear speckle localization
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011405_551590701.3333333333334RegionNecessary for RNA-binding
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+1011510_551590701.3333333333334RegionSufficient for nuclear targeting
HgeneCPSF6chr12:69656342chr7:148512638ENST00000266679+101181_161590701.3333333333334RegionNecessary for nuclear paraspeckles localization
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910358_5515532111.0Region(Microbial infection) Binds to HIV-1 capsid protein p24 (CA)
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910404_5515532111.0RegionSufficient for nuclear speckle localization
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910405_5515532111.0RegionNecessary for RNA-binding
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+910510_5515532111.0RegionSufficient for nuclear targeting
HgeneCPSF6chr12:69656342chr7:148512638ENST00000435070+91081_1615532111.0RegionNecessary for nuclear paraspeckles localization
TgeneEZH2chr12:69656342chr7:148512638ENST000003203561120523_605501752.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000003509951019523_605457708.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000004609111120523_605496747.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000004767731119523_605487696.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000004786541220523_605487696.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000004839671120523_605487738.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000005412201119523_605487696.0Compositional biasNote=Cys-rich
TgeneEZH2chr12:69656342chr7:148512638ENST000003203561120503_605501752.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000003203561120612_727501752.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000003509951019503_605457708.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000003509951019612_727457708.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000004609111120503_605496747.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000004609111120612_727496747.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000004767731119503_605487696.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000004767731119612_727487696.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000004786541220503_605487696.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000004786541220612_727487696.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000004839671120503_605487738.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000004839671120612_727487738.0DomainSET
TgeneEZH2chr12:69656342chr7:148512638ENST000005412201119503_605487696.0DomainCXC
TgeneEZH2chr12:69656342chr7:148512638ENST000005412201119612_727487696.0DomainSET

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for CPSF6-EZH2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19155_19155_1_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000320356_length(transcript)=1184nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGACGGCTCCTCTAACCATGTTTACAACTATCAACCCTGTGATCATCCACGGCAGCCTT
GTGACAGTTCGTGCCCTTGTGTGATAGCACAAAATTTTTGTGAAAAGTTTTGTCAATGTAGTTCAGAGTGTCAAAACCGCTTTCCGGGAT
GCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCCCGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAG
CCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCAAGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTG
ACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTGTGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATG
AAGCTGACAGAAGAGGGAAAGTGTATGATAAATACATGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCA
AGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAAATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTA
TTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGCTGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCG
AAAGAGAAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGG
GCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTGAATTTGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTT
TTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTACCAGTGAATTTTTGCAATAATGCAGTATGGTACATTTTTCAACTTTGAATAAAG

>19155_19155_1_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000320356_length(amino acids)=305AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCD
SSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDV
AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIF

--------------------------------------------------------------
>19155_19155_2_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000350995_length(transcript)=1184nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGACGGCTCCTCTAACCATGTTTACAACTATCAACCCTGTGATCATCCACGGCAGCCTT
GTGACAGTTCGTGCCCTTGTGTGATAGCACAAAATTTTTGTGAAAAGTTTTGTCAATGTAGTTCAGAGTGTCAAAACCGCTTTCCGGGAT
GCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCCCGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAG
CCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCAAGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTG
ACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTGTGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATG
AAGCTGACAGAAGAGGGAAAGTGTATGATAAATACATGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCA
AGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAAATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTA
TTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGCTGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCG
AAAGAGAAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGG
GCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTGAATTTGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTT
TTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTACCAGTGAATTTTTGCAATAATGCAGTATGGTACATTTTTCAACTTTGAATAAAG

>19155_19155_2_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000350995_length(amino acids)=305AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCD
SSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDV
AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIF

--------------------------------------------------------------
>19155_19155_3_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000460911_length(transcript)=1184nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGACGGCTCCTCTAACCATGTTTACAACTATCAACCCTGTGATCATCCACGGCAGCCTT
GTGACAGTTCGTGCCCTTGTGTGATAGCACAAAATTTTTGTGAAAAGTTTTGTCAATGTAGTTCAGAGTGTCAAAACCGCTTTCCGGGAT
GCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCCCGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAG
CCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCAAGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTG
ACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTGTGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATG
AAGCTGACAGAAGAGGGAAAGTGTATGATAAATACATGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCA
AGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAAATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTA
TTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGCTGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCG
AAAGAGAAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGG
GCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTGAATTTGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTT
TTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTACCAGTGAATTTTTGCAATAATGCAGTATGGTACATTTTTCAACTTTGAATAAAG

>19155_19155_3_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000460911_length(amino acids)=305AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCD
SSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDV
AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIF

--------------------------------------------------------------
>19155_19155_4_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000476773_length(transcript)=961nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGGTCAAAACCGCTTTCCGGGATGCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCC
CGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAGCCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCA
AGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTGACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTG
TGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATGAAGCTGACAGAAGAGGGAAAGTGTATGATAAATACA
TGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCAAGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAA
ATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTATTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGC
TGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCGAAAGAGAAATGGAAATCCCTTGACATCTGCTACCTC
CTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGGGCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTG

>19155_19155_4_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000476773_length(amino acids)=263AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKGQNRFPGCRCKAQCNTKQCPC
YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMC

--------------------------------------------------------------
>19155_19155_5_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000478654_length(transcript)=1059nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGGTCAAAACCGCTTTCCGGGATGCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCC
CGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAGCCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCA
AGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTGACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTG
TGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATGAAGCTGACAGAAGAGGGAAAGTGTATGATAAATACA
TGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCAAGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAA
ATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTATTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGC
TGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCGAAAGAGAAATGGAAATCCCTTGACATCTGCTACCTC
CTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGGGCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTG
AATTTGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTTTTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTA

>19155_19155_5_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000478654_length(amino acids)=263AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKGQNRFPGCRCKAQCNTKQCPC
YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMC

--------------------------------------------------------------
>19155_19155_6_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000483967_length(transcript)=1044nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGACGGCTCCTCTAACCATGTTTACAACTATCAACCCTGTGATCATCCACGGCAGCCTT
GTGACAGTTCGTGCCCTTGTGTGATAGCACAAAATTTTTGTGAAAAGTTTTGTCAATGTAGTTCAGAGTGTCAAAACCGCTTTCCGGGAT
GCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCCCGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAG
CCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCAAGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTG
ACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTGTGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATG
AAGCTGACAGAAGAGGGAAAGTGTATGATAAATACATGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCA
AGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAAATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTA
TTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGCTGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCG
AAAGAGAAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGG

>19155_19155_6_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000483967_length(amino acids)=305AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCD
SSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDV
AGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIF

--------------------------------------------------------------
>19155_19155_7_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000541220_length(transcript)=1058nt_BP=172nt
GGAAGATGGCGGACGGCGTGGACCACATAGACATTTACGCGGATGTCGGCGAAGAGTTCAACCAGGAAGCTGAATATGAGAGAGAAGCAG
AGAACGAGAGAGGCACCGGGATCGTGACCGAGACCGTGACCGAGAGCGTGACCGAGAGCGCGAATATCGTCATCGTTAGAAGGTTGTGGG
CTGCACACTGCAGAAAGATACAGCTGAAAAAGGGTCAAAACCGCTTTCCGGGATGCCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCC
CGTGCTACCTGGCTGTCCGAGAGTGTGACCCTGACCTCTGTCTTACTTGTGGAGCCGCTGACCATTGGGACAGTAAAAATGTGTCCTGCA
AGAACTGCAGTATTCAGCGGGGCTCCAAAAAGCATCTATTGCTGGCACCATCTGACGTGGCAGGCTGGGGGATTTTTATCAAAGATCCTG
TGCAGAAAAATGAATTCATCTCAGAATACTGTGGAGAGATTATTTCTCAAGATGAAGCTGACAGAAGAGGGAAAGTGTATGATAAATACA
TGTGCAGCTTTCTGTTCAACTTGAACAATGATTTTGTGGTGGATGCAACCCGCAAGGGTAACAAAATTCGTTTTGCAAATCATTCGGTAA
ATCCAAACTGCTATGCAAAAGTTATGATGGTTAACGGTGATCACAGGATAGGTATTTTTGCCAAGAGAGCCATCCAGACTGGCGAAGAGC
TGTTTTTTGATTACAGATACAGCCAGGCTGATGCCCTGAAGTATGTCGGCATCGAAAGAGAAATGGAAATCCCTTGACATCTGCTACCTC
CTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGGGCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTG
AATTTGCAAAGTACTGTAAGAATAATTTATAGTAATGAGTTTAAAAATCAACTTTTTATTGCCTTCTCACCAGCTGCAAAGTGTTTTGTA

>19155_19155_7_CPSF6-EZH2_CPSF6_chr12_69656342_ENST00000551516_EZH2_chr7_148512638_ENST00000541220_length(amino acids)=263AA_BP=55
MADGVDHIDIYADVGEEFNQEAEYEREAENERGTGIVTETVTESVTESANIVIVRRLWAAHCRKIQLKKGQNRFPGCRCKAQCNTKQCPC
YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CPSF6-EZH2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneEZH2chr12:69656342chr7:148512638ENST000003203561120329_522501.6666666666667752.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000003509951019329_522457.6666666666667708.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000004609111120329_522496.6666666666667747.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000004767731119329_522487.6666666666667696.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000004786541220329_522487.6666666666667696.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000004839671120329_522487.6666666666667738.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST000005412201119329_522487.6666666666667696.0CDYL
TgeneEZH2chr12:69656342chr7:148512638ENST0000032035611201_340501.6666666666667752.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000035099510191_340457.6666666666667708.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000046091111201_340496.6666666666667747.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000047677311191_340487.6666666666667696.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000047865412201_340487.6666666666667696.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000048396711201_340487.6666666666667738.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST0000054122011191_340487.6666666666667696.0DNMT1%2C DNMT3A and DNMT3B
TgeneEZH2chr12:69656342chr7:148512638ENST00000320356112039_68501.6666666666667752.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000350995101939_68457.6666666666667708.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000460911112039_68496.6666666666667747.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000476773111939_68487.6666666666667696.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000478654122039_68487.6666666666667696.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000483967112039_68487.6666666666667738.0EED
TgeneEZH2chr12:69656342chr7:148512638ENST00000541220111939_68487.6666666666667696.0EED


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CPSF6-EZH2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CPSF6-EZH2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource